new release

cl-basic.obo

@@ -3065,7 +3065,7 @@ namespace: cell
 def: "A cell derived from the specialized ectoderm flanking each side of the embryonic neural plate, which after the closure of the neural tube, forms masses of cells that migrate out from the dorsal aspect of the neural tube to spread throughout the body." [MESH:A16.254.600]
 xref: FMA:86667
 is_a: CL:0000219 ! motile cell
-is_a: CL:0002321 ! embryonic cell
+is_a: CL:0011012 ! neural crest cell
 
 [Term]
 id: CL:0000334
@@ -5071,7 +5071,7 @@ xref: BTO:0000876
 xref: CALOHA:TS-0638
 xref: FMA:62864
 is_a: CL:0000766 ! myeloid leukocyte
-is_a: CL:0002087 ! nongranular leukocyte
+is_a: CL:0000842 ! mononuclear cell
 is_a: CL:0011115 ! precursor cell
 
 [Term]
@@ -7234,6 +7234,7 @@ synonym: "DN3 alpha-beta immature T-lymphocyte" EXACT []
 synonym: "DN3 cell" EXACT []
 synonym: "DN3 immature T cell" EXACT []
 synonym: "double negative 3" EXACT []
+synonym: "early cortical thymocyte" BROAD []
 synonym: "preT.DN3.Th" EXACT []
 synonym: "TN3 cell" EXACT []
 synonym: "TN3 thymocyte" EXACT []
@@ -7251,6 +7252,7 @@ synonym: "DN4 cell" EXACT []
 synonym: "DN4 immature T cell" EXACT []
 synonym: "DN4 immature T-cell" EXACT []
 synonym: "double negative 4" EXACT []
+synonym: "early cortical thymocyte" BROAD []
 synonym: "T.DN4.th" EXACT []
 is_a: CL:0002489 ! double negative thymocyte
 
@@ -7263,6 +7265,7 @@ comment: Thymocytes of this stage are undergoing positive and negative selection
 synonym: "double-positive, alpha-beta immature T lymphocyte" EXACT []
 synonym: "DP cell" EXACT []
 synonym: "DP thymocyte" EXACT []
+synonym: "late cortical thymocyte" BROAD []
 is_a: CL:0000790 ! immature alpha-beta T cell
 is_a: CL:0000893 ! thymocyte
 
@@ -7649,6 +7652,7 @@ id: CL:0000842
 name: mononuclear cell
 namespace: cell
 def: "A leukocyte with a single non-segmented nucleus in the mature form." [GOC:add]
+synonym: "mononuclear leukocyte" EXACT []
 synonym: "peripheral blood mononuclear cell" NARROW []
 xref: BTO:0000878
 xref: CALOHA:TS-0768
@@ -9909,7 +9913,7 @@ is_a: CL:0000038 ! erythroid progenitor cell
 id: CL:0001070
 name: beige adipocyte
 namespace: cell
-def: "A fat cell that is beige in color, thermogenic, and which differentiates in white fat tissue from a Myf5-negative progenitor." [] {comment="GOC:add", comment="GOC:cvs", comment="GOC:ymb", comment="PMID:22796012", comment="PMID:25851693"}
+def: "A fat cell that is beige in color, thermogenic, and which differentiates in white fat tissue from a Myf5-negative progenitor." [] {comment="PMID:22796012", comment="GOC:ymb", comment="GOC:add", comment="GOC:cvs", comment="PMID:25851693"}
 synonym: "beige brown adipocyte" EXACT []
 synonym: "beige fat cell" EXACT []
 synonym: "beige/brite adipocyte" EXACT []
@@ -17438,7 +17442,7 @@ id: CL:0007004
 name: premigratory neural crest cell
 namespace: cell
 def: "Cell that is part of the neural crest region of the neuroepithelium, prior to migration. Note that not all premigratory neural crest cells may become migratory neural crest cells." [UBERONREF:0000002]
-is_a: CL:0000003 ! native cell
+is_a: CL:0011012 ! neural crest cell
 created_by: haendel
 creation_date: 2012-06-27T08:27:35Z
 
@@ -17795,6 +17799,13 @@ def: "A neuron that release noradrenaline (noriphinephrine) as a neurotransmitte
 is_a: CL:0000381 ! neurosecretory neuron
 is_a: CL:0000459 ! noradrenergic cell
 
+[Term]
+id: CL:0008026
+name: open tracheal system tracheocyte
+namespace: cell
+def: "An epithelial cell that is part of the epithelium of a tracheal tube in an open tracheal system, such as that found in insects." [GOC:dos]
+is_a: CL:0000066 ! epithelial cell
+
 [Term]
 id: CL:0009000
 name: sensory neuron of spinal nerve
@@ -17843,6 +17854,12 @@ xref: GOC:pr
 xref: http://en.wikipedia.org/wiki/Salivary_gland
 is_a: CL:0002371 ! somatic cell
 
+[Term]
+id: CL:0010000
+name: keratinized cell of hair follicle
+def: "A hair follicle matrix region cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the hair bulb to become the hair medulla cortex and hair root sheath." [https://github.com/obophenotype/cell-ontology/issues/417]
+is_a: CL:2000092 ! hair follicular keratinocyte
+
 [Term]
 id: CL:0010001
 name: stromal cell of bone marrow
@@ -18058,6 +18075,14 @@ name: intermediate mesodermal cell
 def: "A cell derived from the mesoderm that is located between the paraxial mesoderm and the lateral plate." [GOC:NV, ISBN:978-0-87969-707-5]
 is_a: CL:0000222 ! mesodermal cell
 
+[Term]
+id: CL:0011012
+name: neural crest cell
+namespace: cell
+def: "A cell of the neural crest. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesynchymal transition and delamination to form migratory neural crest cells." [0000-0002-9900-7880, orcid.org/0000-0001-5208-3432]
+is_a: CL:0000048 ! multi fate stem cell
+is_a: CL:0002321 ! embryonic cell
+
 [Term]
 id: CL:0011100
 name: galanergic neuron