v2.0.19

rxode2parse 2.0.19

• Added a evid suffix of 60 for cases where evid=2 adds an on event
  (fixes tad() calculation in certain edge cases)

• Initialize all variables to NA

What's Changed

• Fix zero dose + evid=2 to not be counted as dose by @mattfidler in #88
• doubles are declared as NA_REAL by @mattfidler in #92

Full Changelog: v2.0.18...v2.0.19

v2.0.18

• Removed linear compartment solutions with gradients from rxode2parse
  (and rxode2) when compiled with intel c++ compiler (since it crashes
  while compiling).

• Fixed m1mac string issues as requested by CRAN

What's Changed

• Change to literal format for m1mac compiler by @mattfidler in #83
• 84 remove lincmt solved + grad for intel compiler by @mattfidler in #85

Full Changelog: v2.0.17...v2.0.18

v2.0.17

• Added ability to query R user functions in a rxode2 model (will
  force single threaded solve)

• Moved core rxFunParse and rxRmFunParse here so that C and R user
  function clashes can be handled

• Model variables now tracks which compartments have a lag-time
  defined

• For compartment with steady state doses (NONMEM equivalent SS=1,
  SS=2), an additional tracking time-point is added at to track the
  time when the lagged dose is given. As an upshot, the lagged dose
  will start at the steady state concentration shifted by + ii - lag
  in rxode2 (currently for ode systems only)

• This release calculates non bio-availability adjusted duration for
  all rates instead of trying to figure the rate duration during
  solving.

• Make double assignment an error, ie a <- b <-

• NA times are ignored (with warning)

• Steady state bolus doses with addl are treated as non steady state
  events (like what is observed in NONMEM)

• Timsort was upgraded; drop radix support in rxode2 structure

• etTrans now supports keeping logical vectors (with the appropriate
  version of rxode2).

• Security fixes were applied as requested by CRAN

What's Changed

• Add failing tests (and 2 passing tests) by @mattfidler in #45
• Fix warning that does not make sense by @mattfidler in #47
• Test and fix for single subject warning by @mattfidler in #52
• Try to be a bit more careful for windows (and mac?) by @mattfidler in #56
• Add etTrans test and fixes by @mattfidler in #58
• 54 r crashes with na id for all observation rows by @mattfidler in #59
• Add fix and tests by @mattfidler in #60
• 61 back door for exiting with na time by @mattfidler in #62
• Ettrans na time by @mattfidler in #63
• Ss lag by @mattfidler in #42
• 65 ettrans for ss=1ss=2 with addl downgrades to non steady state items by @mattfidler in #66
• 71 feature request r based user defined functions by @mattfidler in #72
• 73 cran by @mattfidler in #74
• 76 cannot keep a logical column by @mattfidler in #77
• Clone to take care of changing source data by @mattfidler in #79
• 80 mem issues by @mattfidler in #81

Full Changelog: v2.0.16...v2.0.17

v2.0.16

• This will remove the CRAN note about not using the imported package data.table. While this is a false positive since it is used in the C code, simply adding it to a dummy fixes this for CRAN.

v2.0.14

rxode2parse 2.0.14

• 'linCmt()' translations of 'alpha', 'beta', 'gamma', 'k21', 'k31',
  'vc' now error instead of ignoring 'gamma' and 'k31' to give 2 cmt
  solution

• transit compartment internal code now changes dose to 0.0 when no
  dose has been administered to the depot compartment. This way dosing
  to the central compartment (without dosing to the transit
  compartment) will not give a NA for the depot compartment (and
  consequently for the central compartment)

• Moved rxDerived here and added tests for it here as well.

• Moved etTransParse here and added tests for it here as well (makes
  up most of etTrans). In addition the following changes were made
  to etTransParse()/etTrans():

  • The internal translation (etTrans()) will not drop times when
    infusions stop. Before, if the infusion stopped after the last
    observation the time when the infusion stopped would be dropped.
    This interferes with linCmt() models.

  • Breaking change/bug fix evid=2 are considered observations when
    translating data to internal rxode2 event structure

  • Fix edge case to find infusion duration when it is the first item
    of the dosing record at time 0.

• Fixed a bug for certain infusions where the rate, ii and/or
  ss data items were dropped from the output when addDosing=TRUE

• Also have internal functions to convert between classic NONMEM
  events and rxode2 events

• Have an internal function that gives information on the linear
  compartmental model translation type, which could be useful for
  babelmixr2

• 'time' in model is now case insensitive

• Use function declaration in rxode2parseGetTranslation() to
  determine thread safety of functions available to rxode2

• Add check for correct number of function arguments to parser.

• Like R, known functions can be assigned as a variable and the
  function can still be called (while not changing the variable
  value). For example you can have a variable gamma as well as a
  function gamma().

• Fix garbled error messages that occur with certain messages.

• Fixed errors that occurred when using capitalized AMT variables in
  the model.

What's Changed

• Parse line syntax err first, only use after w/~ by @mattfidler in #12
• Use number of arguments from rxode2 translations by @mattfidler in #13
• expand rxode2parse to allow testing of #14 by @mattfidler in #15
• Make rxode2parse closer to rxModelVars; Test #17 by @mattfidler in #18
• Add failing test for #19 by @mattfidler in #20
• 21 time column is duplicated in rxsolve output by @mattfidler in #22
• Overly protective (likely fix gctorture/valgrind) by @mattfidler in #25
• 23 pow by @mattfidler in #26
• Commit things taken from the multiexp by @mattfidler in #32
• Et trans by @mattfidler in #35
• Version bump by @mattfidler in #37
• Add error for unsuppored trans by @mattfidler in #40

Full Changelog: v2.0.13...v2.0.14

What's Changed

• Parse line syntax err first, only use after w/~ by @mattfidler in #12
• Use number of arguments from rxode2 translations by @mattfidler in #13
• expand rxode2parse to allow testing of #14 by @mattfidler in #15
• Make rxode2parse closer to rxModelVars; Test #17 by @mattfidler in #18
• Add failing test for #19 by @mattfidler in #20
• 21 time column is duplicated in rxsolve output by @mattfidler in #22
• Overly protective (likely fix gctorture/valgrind) by @mattfidler in #25
• 23 pow by @mattfidler in #26
• Commit things taken from the multiexp by @mattfidler in #32
• Et trans by @mattfidler in #35
• Version bump by @mattfidler in #37
• Add error for unsuppored trans by @mattfidler in #40

Full Changelog: v2.0.13...v2.0.14

v2.0.13

• Change version number for binaries in CRAN.

v2.0.12

rxode2parse 2.0.12

• Bug fix for strict prototypes

• Removed sprintf as noted by CRAN

• Made rxode2parse dll binary independent of rxode2()

What's Changed

• Update DESCRIPTION by @mattfidler in #6
• fix badge by @billdenney in #9
• Remove snprintf by @mattfidler in #10

New Contributors

• @billdenney made their first contribution in #9

Full Changelog: v2.0.11...v2.0.12

v2.0.11

rxode2parse 2.0.11

• Bug fix for strict aliasing as requested by CRAN

Full Changelog: v2.0.10...v2.0.11

v2.0.10

• Use strict aliasing as requested by CRAN

What's Changed

• 1 if cran requests more split before rxode2 admission the code is currently brittle by @mattfidler in #2

New Contributors

• @mattfidler made their first contribution in #2

Full Changelog: https://github.com/nlmixr2/rxode2parse/commits/v2.0.10

v2.0.9

• Initial release to split of rxode2parse from rxode2 to reduce
  compilation time of 'rxode2'

• Added a NEWS.md file to track changes to the package.