Human blastoid

Human blastoids provide a readily accessible, scalable, versatile and perturbable alternative to blastocysts for studying early human development, understanding early pregnancy loss and gaining insights into early developmental defects.

Schematic Summary

Code

To reproduce results:

• https://jlduan.github.io/Human_blastoid

Citation

Leqian Yu#, Yulei Wei#, Jialei Duan#, Daniel A. Schmitz, Masahiro Sakurai, Lei Wang, Kunhua Wang, Shuhua Zhao, Gary C. Hon* & Jun Wu* (2021). Blastocyst-like structures generated from human pluripotent stem cells. Nature 591, 620–626.
DOI: https://doi.org/10.1038/s41586-021-03356-y