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QC for LogNormalDFE (HomSap) #1484

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RyanGutenkunst opened this issue May 18, 2023 · 0 comments
Open

QC for LogNormalDFE (HomSap) #1484

RyanGutenkunst opened this issue May 18, 2023 · 0 comments
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Model QC Quality control process for model addition
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@RyanGutenkunst
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PR for new model: PR
Original paper: paper
Parameter values: DFE parameters are based off the Full model in Table S3, using recent mutation rate estimates
Population indices: N/A

Potential issues that might lead to differences between the model implementations:
SLiM and dadi use different conventions for selection coefficients. In SLiM, the homozygote has fitness 1+s; in dadi it is 1+2s. Since this model was inferred using dadi, to map it to SLiM we need to double the selection coefficient, by shifting the center of the lognormal distribution.

QC'er requests: @petrelharp

@RyanGutenkunst RyanGutenkunst added the Model QC Quality control process for model addition label May 18, 2023
@petrelharp petrelharp changed the title QC for {model_id} ({species}) QC for LogNormalDFE (HomSap) May 19, 2023
@nspope nspope added this to the Version 0.2.1 milestone Jul 6, 2024
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