how should the relationship between a lymph node and the tissues they drain be represented?

[cmungall]

Related to

• Import and use relations from RO (blood vessels) #3221

we have:

id: UBERON:8480056
name: left supraclavicular lymph node
def: "Supraclavicular lymph node located on the left side of a entire appendicular skeleton. The left supraclavicular lymph node drains the kidney, cervix, testis, and pancreas into the thoracic duct." [PMID:31335020]
is_a: UBERON:0035279 ! supraclavicular lymph node

[Term]
id: UBERON:8480057
name: right supraclavicular lymph node
def: "Supraclavicular lymph node located on the right side of a entire appendicular skeleton. The right supraclavicular lymph node drains the breast, lung and upper esophagus into the right lymphatic duct." [PMID:31335020]
is_a: UBERON:0035279 ! supraclavicular lymph node

aside: these need logical defs following the laterality patterns

The textual gloss is biologically correct, but the drains relations we decided on connect a vessel to the drained tissue/organ.

See

• NTR: supplies blood to; drains blood from oborel/obo-relations#699

So following this schema we might have something like

left supraclavicular lymph node CONTINUOUS_WITH left supraclavicular lymphatic vessel [new term] VESSEL_DRAINS_LYMPH_FROM [new relation] lung etc

We would need a new relation here, as it's not blood that is drained, and it doesn't make sense to use the generic drains for lymph and the specific ones for blood

[cmungall]

FWIW FMA has a direct connection on the node, eg

FMA:9579	Perineum	<http://purl.org/sig/ont/fma/lymphatic_drainage>	lymphatic drainage	FMA:5036	Superficial inguinal lymph node
FMA:9600	Prostate	<http://purl.org/sig/ont/fma/lymphatic_drainage>	lymphatic drainage	FMA:229179	Right external iliac lymphatic chain
FMA:9600	Prostate	<http://purl.org/sig/ont/fma/lymphatic_drainage>	lymphatic drainage	FMA:229181	Left external iliac lymphatic chain
FMA:9600	Prostate	<http://purl.org/sig/ont/fma/lymphatic_drainage>	lymphatic drainage	FMA:234280	Sacral lymphatic chain
FMA:9600	Prostate	<http://purl.org/sig/ont/fma/lymphatic_drainage>	lymphatic drainage	FMA:84594	Prostatic lymphatic tree
FMA:9601	Breast	<http://purl.org/sig/ont/fma/lymphatic_drainage>	lymphatic drainage	FMA:236343	Lymphatic tree of breast
FMA:9601	Breast	<http://purl.org/sig/ont/fma/lymphatic_drainage>	lymphatic drainage	FMA:66137	Subclavian lymphatic tree
FMA:9603	Thyroid gland	<http://purl.org/sig/ont/fma/lymphatic_drainage>	lymphatic drainage	FMA:229074	Anterior mediastinal lymphatic chain
FMA:9603	Thyroid gland	<http://purl.org/sig/ont/fma/lymphatic_drainage>	lymphatic drainage	FMA:61235	Thyroid lymph node
FMA:9603	Thyroid gland	<http://purl.org/sig/ont/fma/lymphatic_drainage>	lymphatic drainage	FMA:75631	Brachiocephalic lymphatic chain
FMA:9607	Thymus	<http://purl.org/sig/ont/fma/lymphatic_drainage>	lymphatic drainage	FMA:229074	Anterior mediastinal lymphatic chain
FMA:9607	Thymus	<http://purl.org/sig/ont/fma/lymphatic_drainage>	lymphatic drainage	FMA:5933	Right parasternal lymph node
FMA:9607	Thymus	<http://purl.org/sig/ont/fma/lymphatic_drainage>	lymphatic drainage	FMA:5934	Left parasternal lymph node
FMA:9607	Thymus	<http://purl.org/sig/ont/fma/lymphatic_drainage>	lymphatic drainage	FMA:5951	Right tracheobronchial lymph node
FMA:9607	Thymus	<http://purl.org/sig/ont/fma/lymphatic_drainage>	lymphatic drainage	FMA:5952	Left tracheobronchial lymph node
FMA:9607	Thymus	<http://purl.org/sig/ont/fma/lymphatic_drainage>	lymphatic drainage	FMA:75631	Brachiocephalic lymphatic chain
FMA:9610	Palatine tonsil	<http://purl.org/sig/ont/fma/lymphatic_drainage>	lymphatic drainage	FMA:223860	Superior lateral deep cervical lymphatic chain
FMA:9663	Forearm	<http://purl.org/sig/ont/fma/lymphatic_drainage>	lymphatic drainage	FMA:235642	Superficial lymphatic tree of forearm
F