From 1abc0eb5b21479529a40da6f6f564bec7c332c4f Mon Sep 17 00:00:00 2001 From: dosumis Date: Tue, 30 Apr 2019 13:06:50 +0100 Subject: [PATCH] Adding candidate release artefacts (src/ontology) --- src/ontology/cl-basic.obo | 674 +- src/ontology/cl-basic.owl | 29666 +----------------------------------- src/ontology/cl.owl | 224 +- 3 files changed, 1314 insertions(+), 29250 deletions(-) diff --git a/src/ontology/cl-basic.obo b/src/ontology/cl-basic.obo index 06337e554..b20dcabb7 100644 --- a/src/ontology/cl-basic.obo +++ b/src/ontology/cl-basic.obo @@ -1,8 +1,6 @@ format-version: 1.2 -subsetdef: ubprop:upper_level "abstract upper-level terms not directly useful for analysis" -synonymtypedef: HUMAN_PREFERRED "preferred term when talking about an instance of this class in Homo sapiens" -synonymtypedef: LATIN "latin term" -synonymtypedef: PLURAL "plural term" +data-version: cl/releases/2019-04-26/cl-basic.owl +remark: See PMID:15693950, PMID:12799354, PMID:20123131, PMID:21208450; Contact Alexander Diehl, addiehl@buffalo.edu, University at Buffalo. ontology: cl/cl-basic property_value: http://purl.org/dc/elements/1.1/contributor "Alexander Diehl" xsd:string property_value: http://purl.org/dc/elements/1.1/contributor "Ceri van Slyke" xsd:string @@ -14,7 +12,8 @@ property_value: http://purl.org/dc/elements/1.1/contributor "Nicole Vasilevsky" property_value: http://purl.org/dc/elements/1.1/contributor "Terry Meehan" xsd:string property_value: http://purl.org/dc/elements/1.1/contributor "Yvonne Bradford" xsd:string property_value: http://purl.org/dc/elements/1.1/license http://creativecommons.org/licenses/by/4.0/ -property_value: seeAlso http://obofoundry.org/ontology/cl.html +subsetdef: ro-eco +subsetdef: ubprop:upper_level [Term] id: CL:0000000 @@ -30,6 +29,7 @@ xref: KUPO:0000002 xref: VHOG:0001533 xref: WBbt:0004017 xref: XAO:0003012 +property_value: IAO:0000412 http://purl.obolibrary.org/obo/cl.owl [Term] id: CL:0000001 @@ -81,6 +81,7 @@ id: CL:0000005 name: fibroblast neural crest derived namespace: cell is_a: CL:0000057 ! fibroblast +relationship: RO:0002202 CL:0000008 ! develops from migratory cranial neural crest cell [Term] id: CL:0000006 @@ -119,7 +120,7 @@ id: CL:0000010 name: cultured cell namespace: cell def: "A cell in vitro that is or has been maintained or propagated as part of a cell culture." [ReO:mhb] -comment: Note that this class was re-labeled to 'cultured cell' instead of 'cell line cell', as it intent was clarified to cover any cultured cells of multicellular and unicellular organisms. This includes cells actively being cultured, or cells that have been cultured but are stored in a quiescent state for future use. In having been cultured, cells must establish homeostasis and often replicate in a foreign environment. Accomodation of this stress initiates a selection of cells fit for such challenges, wherein necessary adaptive biochemical and.or genetic changes can occur. These changes can set them apart from the in vivo cells from which they derive, and such changes will typically accumulate and change over increasing time in culture. +comment: Note that this class was re-labeled to 'cultured cell' instead of 'cell line cell', as it intent was clarified to cover any cultured cells of multicellular and unicellular organisms. This includes cells actively being cultured, or cells that have been cultured but are stored in a quiescent state for future use. In having been cultured, cells must establish homeostasis and often replicate in a foreign environment. Accomodation of this stress initiates a selection of cells fit for such challenges, wherein necessary adaptive biochemical and.or genetic changes can occur. These changes can set them apart from the in vivo cells from which they derive, and such changes will typically accumulate and change over increasing time in culture. is_a: CL:0000578 ! experimentally modified cell in vitro [Term] @@ -182,6 +183,7 @@ xref: FBbt:00004936 xref: FMA:84049 xref: WBbt:0006799 is_a: CL:0000015 ! male germ cell +relationship: RO:0002202 CL:0000020 ! develops from spermatogonium [Term] id: CL:0000018 @@ -197,6 +199,7 @@ xref: FMA:72294 xref: WBbt:0006800 is_a: CL:0000015 ! male germ cell is_a: CL:0000413 ! haploid cell +relationship: RO:0002202 CL:0000657 ! develops from secondary spermatocyte [Term] id: CL:0000019 @@ -215,6 +218,7 @@ xref: WBbt:0006798 is_a: CL:0000064 ! ciliated cell is_a: CL:0000219 ! motile cell is_a: CL:0000408 ! male gamete +relationship: RO:0002202 CL:0000018 ! develops from spermatid [Term] id: CL:0000020 @@ -265,6 +269,7 @@ namespace: cell def: "An undifferentiated germ cell that proliferates rapidly and gives rise to oocytes." [GOC:tfm, ISBN:0721662544] xref: FMA:83673 is_a: CL:0000021 ! female germ cell +relationship: RO:0002202 CL:0000670 ! develops from primordial germ cell [Term] id: CL:0000025 @@ -280,6 +285,7 @@ xref: FBbt:00057012 xref: FMA:67343 xref: MA:0000388 is_a: CL:0000675 ! female gamete +relationship: RO:0002202 CL:0000023 ! develops from oocyte [Term] id: CL:0000026 @@ -291,24 +297,28 @@ xref: BTO:0000953 xref: FBbt:00004878 is_a: CL:0000039 ! germ line cell is_a: CL:0000412 ! polyploid cell +relationship: RO:0002202 CL:0000722 ! develops from cystoblast [Term] id: CL:0000027 name: smooth muscle cell neural crest derived namespace: cell is_a: CL:0000192 ! smooth muscle cell +relationship: RO:0002202 CL:0000008 ! develops from migratory cranial neural crest cell [Term] id: CL:0000028 name: CNS neuron (sensu Nematoda and Protostomia) namespace: cell is_a: CL:2000029 ! central nervous system neuron +relationship: RO:0002202 CL:0000338 ! develops from neuroblast (sensu Nematoda and Protostomia) [Term] id: CL:0000029 name: neuron neural crest derived namespace: cell is_a: CL:0000540 ! neuron +relationship: RO:0002202 CL:0002676 ! develops from neural crest derived neuroblast [Term] id: CL:0000030 @@ -316,6 +326,7 @@ name: glioblast namespace: cell xref: FBbt:00005145 is_a: CL:0000055 ! non-terminally differentiated cell +relationship: RO:0002202 CL:0000133 ! develops from neurectodermal cell [Term] id: CL:0000031 @@ -335,6 +346,7 @@ namespace: cell def: "A cell of a platelike structure, especially a thickened plate of ectoderm in the early embryo, from which a sense organ develops." [GOC:tfm, ISBN:0618947256] synonym: "neural placode cell" EXACT [] is_a: CL:0002321 ! embryonic cell +relationship: RO:0002202 CL:0000114 ! develops from surface ectodermal cell [Term] id: CL:0000033 @@ -385,6 +397,7 @@ xref: FMA:86475 xref: VHOG:0001485 is_a: CL:0000723 ! somatic stem cell is_a: CL:0008001 ! hematopoietic precursor cell +relationship: RO:0002202 CL:0000566 ! develops from angioblastic mesenchymal cell [Term] id: CL:0000038 @@ -400,6 +413,7 @@ synonym: "erythroid stem cell" RELATED [] xref: BTO:0004911 is_a: CL:0000764 ! erythroid lineage cell is_a: CL:0000839 ! myeloid lineage restricted progenitor cell +relationship: RO:0002202 CL:0000050 ! develops from megakaryocyte-erythroid progenitor cell [Term] id: CL:0000039 @@ -409,6 +423,7 @@ def: "A cell that is within the developmental lineage of gametes and is able to comment: Originally this term had some plant germ line cell children. subset: ubprop:upper_level is_a: CL:0000548 ! animal cell +disjoint_from: CL:0002371 ! somatic cell [Term] id: CL:0000040 @@ -424,6 +439,7 @@ xref: CALOHA:TS-1195 xref: FMA:83553 is_a: CL:0000763 ! myeloid cell is_a: CL:0002194 ! monopoietic cell +relationship: RO:0002202 CL:0002009 ! develops from macrophage dendritic cell progenitor [Term] id: CL:0000041 @@ -438,6 +454,7 @@ synonym: "polymorphonuclear leucocyte" BROAD [] synonym: "polymorphonuclear leukocyte" BROAD [] is_a: CL:0000771 ! eosinophil is_a: CL:0002242 ! nucleate cell +relationship: RO:0002202 CL:0000774 ! develops from band form eosinophil [Term] id: CL:0000042 @@ -448,6 +465,7 @@ comment: These cells are CD11b-negative, CD15-negative, CD16-negative, CD35-nega synonym: "neutrophilic granuloblast" RELATED [] is_a: CL:0000834 ! neutrophil progenitor cell is_a: CL:0000835 ! myeloblast +relationship: RO:0002202 CL:0000834 ! develops from neutrophil progenitor cell [Term] id: CL:0000043 @@ -465,6 +483,7 @@ xref: CALOHA:TS-0688 is_a: CL:0000767 ! basophil is_a: CL:0002242 ! nucleate cell is_a: CL:0002274 ! histamine secreting cell +relationship: RO:0002202 CL:0000770 ! develops from band form basophil [Term] id: CL:0000045 @@ -493,7 +512,7 @@ xref: BTO:0002881 xref: CALOHA:TS-2360 xref: FMA:86684 is_a: CL:0000048 ! multi fate stem cell -is_a: CL:0002319 ! neural cell +relationship: RO:0002202 CL:0000133 ! develops from neurectodermal cell [Term] id: CL:0000048 @@ -524,6 +543,9 @@ synonym: "myeloid stem cell" RELATED [ISBN:0878932437] synonym: "pluripotent stem cell (bone marrow)" RELATED [ISBN:0878932437] xref: BTO:0004730 is_a: CL:0002032 ! hematopoietic oligopotent progenitor cell +disjoint_from: CL:0000050 ! megakaryocyte-erythroid progenitor cell +disjoint_from: CL:0000051 ! common lymphoid progenitor +disjoint_from: CL:0000557 ! granulocyte monocyte progenitor cell [Term] id: CL:0000050 @@ -541,6 +563,8 @@ synonym: "MEP" EXACT [] is_a: CL:0000763 ! myeloid cell is_a: CL:0002032 ! hematopoietic oligopotent progenitor cell is_a: CL:0011115 ! precursor cell +disjoint_from: CL:0000557 ! granulocyte monocyte progenitor cell +disjoint_from: CL:0002009 ! macrophage dendritic cell progenitor [Term] id: CL:0000051 @@ -610,6 +634,7 @@ xref: CALOHA:TS-0362 xref: FMA:63877 xref: VHOG:0001482 is_a: CL:0002320 ! connective tissue cell +relationship: RO:0002202 CL:0000134 ! develops from mesenchymal stem cell [Term] id: CL:0000058 @@ -621,6 +646,7 @@ xref: BTO:0003607 xref: FMA:66783 is_a: CL:0000055 ! non-terminally differentiated cell is_a: CL:0002320 ! connective tissue cell +relationship: RO:0002202 CL:0007009 ! develops from prechondroblast [Term] id: CL:0000059 @@ -637,6 +663,7 @@ xref: FMA:70576 is_a: CL:0000146 ! simple columnar epithelial cell is_a: CL:0000151 ! secretory cell is_a: CL:0002077 ! ecto-epithelial cell +relationship: RO:0002202 CL:0007000 ! develops from preameloblast [Term] id: CL:0000060 @@ -650,6 +677,7 @@ xref: FMA:62999 is_a: CL:0000055 ! non-terminally differentiated cell is_a: CL:0000710 ! neurecto-epithelial cell is_a: CL:0002159 ! general ecto-epithelial cell +relationship: RO:0002202 CL:0007003 ! develops from preodontoblast [Term] id: CL:0000061 @@ -663,6 +691,7 @@ xref: CALOHA:TS-1164 xref: FMA:63002 is_a: CL:0000062 ! osteoblast is_a: CL:0000151 ! secretory cell +relationship: RO:0002202 CL:0007002 ! develops from precementoblast [Term] id: CL:0000062 @@ -675,6 +704,7 @@ xref: CALOHA:TS-0720 xref: FMA:66780 is_a: CL:0000055 ! non-terminally differentiated cell is_a: CL:0002320 ! connective tissue cell +relationship: RO:0002202 CL:0007010 ! develops from preosteoblast [Term] id: CL:0000063 @@ -720,6 +750,7 @@ xref: FBbt:00000124 xref: FMA:66768 xref: WBbt:0003672 is_a: CL:0000548 ! animal cell +disjoint_from: CL:0000738 ! leukocyte [Term] id: CL:0000067 @@ -757,6 +788,7 @@ def: "An endothelial cell that lines the vasculature." [GOC:tfm] synonym: "cuboidal endothelial cell of vascular tree" EXACT [] is_a: CL:0000076 ! squamous epithelial cell is_a: CL:0002139 ! endothelial cell of vascular tree +relationship: RO:0002202 CL:0002546 ! develops from embryonic blood vessel endothelial progenitor cell [Term] id: CL:0000072 @@ -818,6 +850,7 @@ name: stratified epithelial cell namespace: cell is_a: CL:0000066 ! epithelial cell is_a: CL:0002371 ! somatic cell +relationship: RO:0002202 CL:0000357 ! develops from stratified epithelial stem cell [Term] id: CL:0000080 @@ -852,6 +885,7 @@ synonym: "pancreatic epithelial cell" EXACT [] xref: BTO:0000028 is_a: CL:0000066 ! epithelial cell is_a: CL:0002371 ! somatic cell +relationship: RO:0002202 CL:0000223 ! develops from endodermal cell [Term] id: CL:0000084 @@ -870,6 +904,9 @@ xref: CALOHA:TS-1001 xref: FMA:62870 xref: VHOG:0001479 is_a: CL:0000542 ! lymphocyte +disjoint_from: CL:0000623 ! natural killer cell +disjoint_from: CL:0000945 ! lymphocyte of B lineage +relationship: RO:0002202 CL:0000827 ! develops from pro-T cell [Term] id: CL:0000085 @@ -943,6 +980,7 @@ xref: CALOHA:TS-0721 xref: FMA:66781 is_a: CL:0000766 ! myeloid leukocyte is_a: CL:0001035 ! bone cell +relationship: RO:0002202 CL:0000576 ! develops from monocyte [Term] id: CL:0000093 @@ -972,6 +1010,7 @@ id: CL:0000095 name: neuron associated cell namespace: cell is_a: CL:0002319 ! neural cell +relationship: RO:0002202 CL:0000133 ! develops from neurectodermal cell [Term] id: CL:0000096 @@ -1011,6 +1050,7 @@ xref: CALOHA:TS-0603 xref: FMA:66784 is_a: CL:0000766 ! myeloid leukocyte is_a: CL:0002274 ! histamine secreting cell +relationship: RO:0002202 CL:0000831 ! develops from mast cell progenitor [Term] id: CL:0000098 @@ -1185,6 +1225,7 @@ id: CL:0000117 name: CNS neuron (sensu Vertebrata) namespace: cell is_a: CL:2000029 ! central nervous system neuron +relationship: RO:0002202 CL:0000337 ! develops from neuroblast (sensu Vertebrata) [Term] id: CL:0000118 @@ -1240,6 +1281,7 @@ id: CL:0000123 name: neuron associated cell (sensu Vertebrata) namespace: cell is_a: CL:0000095 ! neuron associated cell +relationship: RO:0002202 CL:0000333 ! develops from migratory neural crest cell [Term] id: CL:0000124 @@ -1247,6 +1289,7 @@ name: glial cell (sensu Nematoda and Protostomia) namespace: cell xref: FBbt:00005144 is_a: CL:0000125 ! glial cell +relationship: RO:0002202 CL:0000340 ! develops from glioblast (sensu Nematoda and Protostomia) [Term] id: CL:0000125 @@ -1259,6 +1302,7 @@ xref: BTO:0002606 xref: CALOHA:TS-0415 xref: FMA:54536 is_a: CL:0000095 ! neuron associated cell +relationship: RO:0002202 CL:0000030 ! develops from glioblast [Term] id: CL:0000126 @@ -1295,6 +1339,7 @@ xref: BTO:0000962 xref: CALOHA:TS-0709 xref: FMA:54540 is_a: CL:0000126 ! macroglial cell +relationship: RO:0002202 CL:0002453 ! develops from oligodendrocyte precursor cell [Term] id: CL:0000129 @@ -1314,6 +1359,7 @@ xref: FMA:54539 xref: FMA:54540 is_a: CL:0000243 ! glial cell (sensu Vertebrata) is_a: CL:0000878 ! central nervous system macrophage +relationship: RO:0002202 CL:0002453 ! develops from oligodendrocyte precursor cell [Term] id: CL:0000130 @@ -1326,6 +1372,7 @@ id: CL:0000131 name: gut endothelial cell namespace: cell is_a: CL:0000115 ! endothelial cell +relationship: RO:0002202 CL:0000223 ! develops from endodermal cell [Term] id: CL:0000132 @@ -1336,6 +1383,7 @@ xref: CALOHA:TS-0172 xref: FMA:70614 is_a: CL:0000076 ! squamous epithelial cell is_a: CL:0000710 ! neurecto-epithelial cell +relationship: RO:0002202 CL:0000008 ! develops from migratory cranial neural crest cell [Term] id: CL:0000133 @@ -1379,6 +1427,7 @@ def: "An inactive fibroblast; cytoplasm is sparse, endoplasmic reticulum is scan comment: Cultured human fibrocytes are MHCI-positive, MHCII-positive, CD1a-negative, CD3-negative, CD4-negative, CD8-negative, CD10-negative, CD11b-positive, CD13-positive, CD14-negative, CD16-negative, CD18-positive, CD19-negative, CD25-negative, CD29-positive, CD32-positive, CD33-negative, CD34-positive, CD38-negative, CD40-positive, CD44-negative, CD45RO-positive, CD49a-positive, CD49b-positive, CD49c-negative, CD49d-negative, CD49e-positive, CD49f-negative, CD56-negative, CD58-positive, CD61-positive, CD64-positive, CD70-negative, CD71-positive, CD80-positive, CD83-negative, CD86-positive, CD103-negative, CD105-positive, CD181-positive, CD182-negative, CD183-positive, CD184-positive, CD185-negative, CD186-negative, CD191-positive, CD192-negative, CD193-positive, CD194-positive, CD195-positive, CD196-negative, CD197-positive, CD199-positive, desmin-negative, F4/80-positive, Gr1-positive, LSP-1-positive, MHCI-positive, MHCII-positive, alpha-SMA-negative, TCRab-negative, TCRgd-negative, and vimentin-positive. Fibrocytes are also capable of secreting angiogenin, bFGF, CCL2, CCL3, CCL4, CCL8, CXCL1, type I collagen, type III collagen, CTGF, fibronectin, GM-CSF, IL-1a, IL-6, IL-8, IL-10, M-CSF, MMP-9, PDGF-A, TGF-alpha, TGF-beta1, TNF-alpha, and VEGF-A. xref: FMA:63879 is_a: CL:0000499 ! stromal cell +relationship: RO:0002202 CL:0000057 ! develops from fibroblast [Term] id: CL:0000136 @@ -1393,6 +1442,7 @@ xref: CALOHA:TS-0012 xref: FMA:63880 is_a: CL:0000325 ! stuff accumulating cell is_a: CL:0002320 ! connective tissue cell +relationship: RO:0002202 CL:0000134 ! develops from mesenchymal stem cell [Term] id: CL:0000137 @@ -1406,6 +1456,7 @@ xref: CALOHA:TS-1167 xref: FMA:66779 xref: VSAO:0000124 is_a: CL:0001035 ! bone cell +relationship: RO:0002202 CL:0001040 ! develops from non-terminally differentiated osteoblast [Term] id: CL:0000138 @@ -1418,6 +1469,7 @@ xref: CALOHA:TS-0138 xref: FMA:66782 is_a: CL:0000153 ! glycosaminoglycan secreting cell is_a: CL:0000667 ! collagen secreting cell +relationship: RO:0002202 CL:0000058 ! develops from chondroblast [Term] id: CL:0000140 @@ -1425,6 +1477,8 @@ name: odontocyte namespace: cell def: "Skeletogenic cell that secretes dentine matrix, is derived from odontogenic papilla. Embedded in dentine tissue, and is the transformation of a non-terminally differentiated odontoblast cell." [GO_REF:0000034] is_a: CL:0002320 ! connective tissue cell +relationship: RO:0002202 CL:0000060 ! develops from odontoblast +relationship: RO:0002202 CL:0000134 ! develops from mesenchymal stem cell [Term] id: CL:0000141 @@ -1434,6 +1488,7 @@ def: "An osteocytelike cell with numerous processes, trapped in a lacuna in the comment: CHECK: wikipedia says that cementocytes no longer produce cementum, but the phenoscape def is: Skeletogenic cell that produces cementum, is part of the odontogenic papilla, and is a transformation of a cementoblast cell (no change to existing def). xref: FMA:63003 is_a: CL:0000137 ! osteocyte +relationship: RO:0002202 CL:0000061 ! develops from cementoblast [Term] id: CL:0000142 @@ -1500,6 +1555,7 @@ xref: FMA:70545 xref: VHOG:0001679 is_a: CL:0000147 ! pigment cell is_a: CL:0002371 ! somatic cell +relationship: RO:0002202 CL:0000541 ! develops from melanoblast [Term] id: CL:0000149 @@ -1667,6 +1723,7 @@ synonym: "phaeochromocyte" EXACT [] xref: BTO:0000259 xref: FMA:69263 is_a: CL:0000568 ! amine precursor uptake and decarboxylation cell +relationship: RO:0002202 CL:0000333 ! develops from migratory neural crest cell [Term] id: CL:0000167 @@ -1707,6 +1764,7 @@ is_a: CL:0000083 ! epithelial cell of pancreas is_a: CL:0000164 ! enteroendocrine cell is_a: CL:0000168 ! insulin secreting cell is_a: CL:0008024 ! pancreatic endocrine cell +relationship: RO:0002202 CL:0002351 ! develops from progenitor cell of endocrine pancreas [Term] id: CL:0000170 @@ -1729,6 +1787,7 @@ xref: FMA:70585 is_a: CL:0000083 ! epithelial cell of pancreas is_a: CL:0002067 ! type A enterocrine cell is_a: CL:0008024 ! pancreatic endocrine cell +relationship: RO:0002202 CL:0002351 ! develops from progenitor cell of endocrine pancreas [Term] id: CL:0000172 @@ -1752,6 +1811,7 @@ xref: FMA:70587 is_a: CL:0000083 ! epithelial cell of pancreas is_a: CL:0000502 ! type D enteroendocrine cell is_a: CL:0008024 ! pancreatic endocrine cell +relationship: RO:0002202 CL:0002351 ! develops from progenitor cell of endocrine pancreas [Term] id: CL:0000174 @@ -1828,6 +1888,7 @@ is_a: CL:0000066 ! epithelial cell is_a: CL:0000181 ! metabolising cell is_a: CL:0000417 ! endopolyploid cell is_a: CL:0002371 ! somatic cell +relationship: RO:0002202 CL:0005026 ! develops from hepatoblast [Term] id: CL:0000183 @@ -1878,6 +1939,7 @@ is_a: CL:0000183 ! contractile cell is_a: CL:0000393 ! electrically responsive cell is_a: CL:0000548 ! animal cell is_a: CL:0002371 ! somatic cell +relationship: RO:0002202 CL:0000056 ! develops from myoblast [Term] id: CL:0000188 @@ -1898,6 +1960,7 @@ def: "A muscle cell that develops tension more slowly than a fast-twitch fiber." synonym: "slow muscle fiber" RELATED [ISBN:0815316208] xref: FMA:84448 is_a: CL:0008002 ! skeletal muscle fiber +relationship: RO:0002202 CL:0000857 ! develops from slow muscle myoblast [Term] id: CL:0000190 @@ -1906,6 +1969,7 @@ namespace: cell def: "A muscle cell that can develop high tension rapidly. It is usually innervated by a single alpha neuron ." [GOC:tfm, ISBN:0323052908] synonym: "glycolytic muscle fiber" EXACT [] is_a: CL:0008002 ! skeletal muscle fiber +relationship: RO:0002202 CL:0000858 ! develops from fast muscle myoblast [Term] id: CL:0000192 @@ -1922,6 +1986,7 @@ xref: CALOHA:TS-2159 xref: FMA:14072 is_a: CL:0008000 ! non-striated muscle cell is_a: CL:0008007 ! visceral muscle cell +relationship: RO:0002202 CL:0000514 ! develops from smooth muscle myoblast [Term] id: CL:0000193 @@ -1930,6 +1995,7 @@ namespace: cell alt_id: CL:0000466 def: "A striated muscle cell of an arthropod heart that participates in heart contraction." [MESH:A11.620.500] is_a: CL:0000746 ! cardiac muscle cell +relationship: RO:0002202 CL:0000465 ! develops from cardioblast (sensu Arthropoda) [Term] id: CL:0000194 @@ -2143,6 +2209,7 @@ xref: FMA:62121 is_a: CL:0000217 ! insulating cell is_a: CL:0000328 ! myelin accumulating cell is_a: CL:0002573 ! Schwann cell +relationship: RO:0002202 CL:0002377 ! develops from immature Schwann cell [Term] id: CL:0000219 @@ -2208,13 +2275,14 @@ def: "A cell that lacks a nucleus." [FB:ma] synonym: "non-nucleated cell" EXACT [] xref: FMA:68647 is_a: CL:0000003 ! native cell +disjoint_from: CL:0002242 ! nucleate cell [Term] id: CL:0000226 name: single nucleate cell namespace: cell def: "A cell with a single nucleus." [FB:ma, GOC:tfm] -is_a: CL:0002242 ! nucleate cell +is_a: CL:0000003 ! native cell [Term] id: CL:0000227 @@ -2232,7 +2300,7 @@ synonym: "syncytial cell" EXACT [] synonym: "syncytium" EXACT [] xref: AEO:0000203 xref: WBbt:0008074 -is_a: CL:0002242 ! nucleate cell +is_a: CL:0000003 ! native cell [Term] id: CL:0000229 @@ -2271,6 +2339,7 @@ xref: FMA:81100 is_a: CL:0000081 ! blood cell is_a: CL:0000329 ! oxygen accumulating cell is_a: CL:0000764 ! erythroid lineage cell +relationship: RO:0002202 CL:0000558 ! develops from reticulocyte [Term] id: CL:0000233 @@ -2288,6 +2357,7 @@ is_a: CL:0000081 ! blood cell is_a: CL:0000225 ! anucleate cell is_a: CL:0000458 ! serotonin secreting cell is_a: CL:0000763 ! myeloid cell +relationship: RO:0002202 CL:0000556 ! develops from megakaryocyte [Term] id: CL:0000234 @@ -2313,6 +2383,7 @@ xref: FMA:63261 xref: FMA:83585 is_a: CL:0000234 ! phagocyte is_a: CL:0000766 ! myeloid leukocyte +relationship: RO:0002202 CL:0000576 ! develops from monocyte [Term] id: CL:0000236 @@ -2335,6 +2406,7 @@ namespace: cell is_a: CL:0000240 ! stratified squamous epithelial cell is_a: CL:0000311 ! keratin accumulating cell is_a: CL:0002077 ! ecto-epithelial cell +relationship: RO:0002202 CL:0000114 ! develops from surface ectodermal cell [Term] id: CL:0000238 @@ -2378,6 +2450,7 @@ name: glial cell (sensu Vertebrata) namespace: cell def: "A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Form the myelin insulation of nervous pathways, guide neuronal migration during development, and exchange metabolites with neurons. Neuroglia have high-affinity transmitter uptake systems, voltage-dependent and transmitter-gated ion channels, and can release transmitters, but their role in signaling (as in many other functions) is unclear." [MESH:A08.637] is_a: CL:0000125 ! glial cell +relationship: RO:0002202 CL:0000339 ! develops from glioblast (sensu Vertebrata) [Term] id: CL:0000244 @@ -2473,6 +2546,7 @@ id: CL:0000255 name: eukaryotic cell namespace: cell is_a: CL:0000003 ! native cell +disjoint_from: CL:0000520 ! prokaryotic cell [Term] id: CL:0000256 @@ -2512,6 +2586,10 @@ is_obsolete: true id: CL:0000261 name: anterior cell namespace: cell +comment: Obsoleted becuase this term has an overly general name, no definition, and by it's classification appears to refer to a very specific cell type in dictystelium. If needed, the term should be in DDANAT - probably as a subclass of http://purl.obolibrary.org/obo/DDANAT_0000002 +is_obsolete: true +consider: false +consider: http://purl.obolibrary.org/obo/DDANAT_0000002 [Term] id: CL:0000262 @@ -2852,6 +2930,7 @@ comment: This class is for the vertebrate tracheal structure. For the analagous synonym: "tracheocyte" EXACT [] xref: FMA:74793 is_a: CL:0002202 ! epithelial cell of tracheobronchial tree +relationship: RO:0002202 CL:0000377 ! develops from tracheoblast [Term] id: CL:0000308 @@ -2987,6 +3066,7 @@ id: CL:0000324 name: metanephric mesenchyme stem cell namespace: cell is_a: CL:0000134 ! mesenchymal stem cell +relationship: RO:0002202 CL:0000222 ! develops from mesodermal cell [Term] id: CL:0000325 @@ -3054,6 +3134,7 @@ def: "A cell derived from the specialized ectoderm flanking each side of the emb xref: FMA:86667 is_a: CL:0000219 ! motile cell is_a: CL:0011012 ! neural crest cell +relationship: RO:0002202 CL:0007004 ! develops from premigratory neural crest cell [Term] id: CL:0000334 @@ -3081,6 +3162,7 @@ synonym: "medullary chromaffin cell of adrenal gland" EXACT [FMA:69262] xref: FMA:69262 is_a: CL:0000457 ! biogenic amine secreting cell is_a: CL:1000426 ! chromaffin cell of adrenal gland +relationship: RO:0002202 CL:0000011 ! develops from migratory trunk neural crest cell [Term] id: CL:0000337 @@ -3148,6 +3230,7 @@ namespace: cell def: "A mesenchymal cell that is part of a small mass of condensed mesenchyme in the enamel organ; it differentiates into the dentin and dental pulp." [GOC:tfm, ISBN:0721662544] comment: Merge with odontoblast? is_a: CL:0008019 ! mesenchymal cell +relationship: RO:0002202 CL:0000008 ! develops from migratory cranial neural crest cell [Term] id: CL:0000346 @@ -3156,6 +3239,7 @@ namespace: cell def: "A specialized mesenchymal cell that resides in the dermal papilla located at the bottom of hair follicles. This cell plays a pivotal roles in hair formation, growth, and cycling." [GOC:tfm, PMID:9893172] comment: Are these really all stem cells? is_a: CL:0000134 ! mesenchymal stem cell +relationship: RO:0002202 CL:0000333 ! develops from migratory neural crest cell [Term] id: CL:0000347 @@ -3163,6 +3247,7 @@ name: scleral cell namespace: cell def: "A cell of the sclera of the eye." [GOC:add] is_a: CL:0000293 ! structural cell +relationship: RO:0002202 CL:0000008 ! develops from migratory cranial neural crest cell [Term] id: CL:0000348 @@ -3170,6 +3255,7 @@ name: choroidal cell of the eye namespace: cell def: "A cell of the choroid of the eye." [GOC:add] is_a: CL:0000293 ! structural cell +relationship: RO:0002202 CL:0000008 ! develops from migratory cranial neural crest cell [Term] id: CL:0000349 @@ -3318,7 +3404,7 @@ def: "Obsolete. Use PO:0000084 from Plant Ontology instead. Male gamete, part of comment: replaced_by: PO:0000084 synonym: "gametophyte sperm cell" RELATED [] synonym: "male gametophyte sperm cell" RELATED [] -synonym: "pollen germ cell " RELATED [] +synonym: "pollen germ cell" RELATED [] is_obsolete: true [Term] @@ -3438,6 +3524,7 @@ id: CL:0000383 name: nephrogenic mesenchyme stem cell namespace: cell is_a: CL:0000134 ! mesenchymal stem cell +relationship: RO:0002202 CL:0000134 ! develops from mesenchymal stem cell [Term] id: CL:0000384 @@ -3464,6 +3551,7 @@ name: hemocyte (sensu Nematoda and Protostomia) namespace: cell xref: FBbt:00005063 is_a: CL:0000519 ! phagocyte (sensu Nematoda and Protostomia) +relationship: RO:0002202 CL:0000385 ! develops from prohemocyte (sensu Nematoda and Protostomia) [Term] id: CL:0000388 @@ -3496,6 +3584,7 @@ namespace: cell def: "An insect immune cell that develops from plasmatocyte." [PMID:12930778] xref: FBbt:00001688 is_a: CL:0000387 ! hemocyte (sensu Nematoda and Protostomia) +relationship: RO:0002202 CL:0000394 ! develops from plasmatocyte [Term] id: CL:0000392 @@ -3775,6 +3864,7 @@ namespace: cell def: "A pigment cell derived from the neural crest. Contains cartenoid pigments in structures called pterinosomes or xanthosomes. This gives an appearance ranging from a golden yellow to orange and red." [SANBI:mhl] synonym: "xanthophore" RELATED [] is_a: CL:0000147 ! pigment cell +relationship: RO:0002202 CL:0005002 ! develops from xanthoblast [Term] id: CL:0000431 @@ -3783,6 +3873,7 @@ namespace: cell def: "A pigment cell derived from the neural crest. The cell contains flat light-reflecting platelets, probably of guanine, in stacks called reflecting platets or iridisomes. The color-generating components produce a silver, gold, or iridescent color." [SANBI:mhl] synonym: "guanophore" RELATED [] is_a: CL:0000147 ! pigment cell +relationship: RO:0002202 CL:0005001 ! develops from iridoblast [Term] id: CL:0000432 @@ -3931,6 +4022,7 @@ synonym: "white fat cell" EXACT [] xref: CALOHA:TS-1119 xref: FMA:83434 is_a: CL:0000136 ! fat cell +relationship: RO:0002202 CL:0002334 ! develops from preadipocyte [Term] id: CL:0000449 @@ -3942,6 +4034,7 @@ synonym: "brown adipose cell" EXACT [] xref: CALOHA:TS-0099 xref: FMA:83435 is_a: CL:0000136 ! fat cell +relationship: RO:0002202 CL:0002335 ! develops from brown preadipocyte [Term] id: CL:0000451 @@ -3954,6 +4047,7 @@ xref: BTO:0002042 xref: CALOHA:TS-0194 xref: FMA:83036 is_a: CL:0000738 ! leukocyte +disjoint_from: CL:0000542 ! lymphocyte [Term] id: CL:0000452 @@ -3974,6 +4068,7 @@ xref: CALOHA:TS-2375 xref: FMA:63072 is_a: CL:0000766 ! myeloid leukocyte is_a: CL:0000990 ! conventional dendritic cell +relationship: RO:0002202 CL:0000763 ! develops from myeloid cell [Term] id: CL:0000454 @@ -4044,6 +4139,7 @@ def: "An epidermal cell that secretes chitinous cuticle from its apical side." [ comment: While insect epidermis is generally columnar/cuboidal, there are certainly well studied cases where it is not (e.g.- Rhodnius prolixus when starved). So it would be safer to add this as a differentium for particular species where this is known. -DSJ. is_a: CL:0000362 ! epidermal cell is_a: CL:0000710 ! neurecto-epithelial cell +relationship: RO:0002202 CL:0000464 ! develops from epidermoblast [Term] id: CL:0000464 @@ -4053,6 +4149,7 @@ def: "An epidermal progenitor cell that arises from neuroectoderm and in turn gi xref: FBbt:00004994 is_a: CL:0000055 ! non-terminally differentiated cell is_a: CL:0000710 ! neurecto-epithelial cell +relationship: RO:0002202 CL:0000114 ! develops from surface ectodermal cell [Term] id: CL:0000465 @@ -4148,6 +4245,7 @@ comment: Editors note: check this. Currently used in goxp synonym: "ovarian follicle cell" EXACT [GO:0007297] xref: FBbt:00004904 is_a: CL:0000075 ! columnar/cuboidal epithelial cell +relationship: RO:0002202 CL:0000441 ! develops from follicle stem cell [Term] id: CL:0000478 @@ -4274,6 +4372,7 @@ xref: CALOHA:TS-1146 xref: FMA:70572 is_a: CL:0000624 ! CD4-positive, alpha-beta T cell is_a: CL:0000912 ! helper T cell +relationship: RO:0002202 CL:0000896 ! develops from activated CD4-positive, alpha-beta T cell [Term] id: CL:0000493 @@ -4327,6 +4426,7 @@ def: "A connective tissue cell of an organ found in the loose connective tissue. xref: BTO:0002064 xref: FMA:83624 is_a: CL:0002320 ! connective tissue cell +relationship: RO:0002202 CL:0000134 ! develops from mesenchymal stem cell [Term] id: CL:0000500 @@ -4404,7 +4504,7 @@ id: CL:0000508 name: type G enteroendocrine cell namespace: cell def: "An endocrine cell found in the pyloric gland mucosa (antral mucosa) of the stomach of mammals and responsible for the secretion of gastrin and enkephalin. Most abundant in pyloric antrum, pyramidal in form with a narrow apex bearing long microvilli." [GOC:tfm, ISBN:0517223651, MESH:A03.492.766.440.300] -synonym: "G cell " EXACT [] +synonym: "G cell" EXACT [] xref: BTO:0004108 xref: FMA:67609 is_a: CL:0000164 ! enteroendocrine cell @@ -4474,6 +4574,7 @@ def: "A myoblast that differentiates into skeletal muscle fibers." [SANBI:mhl] synonym: "skeletal myoblast" EXACT [] xref: FMA:84799 is_a: CL:0000056 ! myoblast +relationship: RO:0002202 CL:0000355 ! develops from multi-potent skeletal muscle stem cell [Term] id: CL:0000516 @@ -4493,6 +4594,7 @@ name: macrophage derived foam cell namespace: cell def: "A type of foam cell derived from a macrophage containing lipids in small vacuoles and typically seen in atherolosclerotic lesions, as well as other conditions." [GOC:add, PMID:20213546] is_a: CL:0000891 ! foam cell +relationship: RO:0002202 CL:0000235 ! develops from macrophage [Term] id: CL:0000518 @@ -4519,6 +4621,7 @@ id: CL:0000521 name: fungal cell namespace: cell is_a: CL:0000255 ! eukaryotic cell +disjoint_from: CL:0000548 ! animal cell [Term] id: CL:0000522 @@ -4674,6 +4777,8 @@ xref: WBbt:0003679 is_a: CL:0000393 ! electrically responsive cell is_a: CL:0000404 ! electrically signaling cell is_a: CL:0002319 ! neural cell +relationship: RO:0002202 CL:0000031 ! develops from neuroblast +property_value: IAO:0000412 http://purl.obolibrary.org/obo/cl.owl [Term] id: CL:0000541 @@ -4685,6 +4790,7 @@ xref: BTO:0003217 xref: FMA:83377 is_a: CL:0000055 ! non-terminally differentiated cell is_a: CL:0002371 ! somatic cell +relationship: RO:0002202 CL:0000333 ! develops from migratory neural crest cell [Term] id: CL:0000542 @@ -4698,6 +4804,8 @@ xref: FMA:62863 xref: VHOG:0001535 is_a: CL:0002087 ! nongranular leukocyte is_a: CL:0002242 ! nucleate cell +disjoint_from: CL:0000766 ! myeloid leukocyte +relationship: RO:0002202 CL:0000051 ! develops from common lymphoid progenitor [Term] id: CL:0000543 @@ -4762,6 +4870,7 @@ synonym: "rubriblast" EXACT [ISBN:0721601464] xref: FMA:83518 is_a: CL:0000764 ! erythroid lineage cell is_a: CL:0002242 ! nucleate cell +relationship: RO:0002202 CL:0000038 ! develops from erythroid progenitor cell [Term] id: CL:0000548 @@ -4795,6 +4904,7 @@ synonym: "polychromatophilic normoblast" EXACT [ISBN:0721601464] synonym: "rubricyte" EXACT [ISBN:0721601464] xref: FMA:83506 is_a: CL:0000765 ! erythroblast +relationship: RO:0002202 CL:0000549 ! develops from basophilic erythroblast [Term] id: CL:0000551 @@ -4814,6 +4924,7 @@ synonym: "orthochromatic normoblast" EXACT [ISBN:0721601464] synonym: "pyknotic eto enrythroblast" EXACT [ISBN:0721601464] xref: FMA:84646 is_a: CL:0000765 ! erythroblast +relationship: RO:0002202 CL:0000550 ! develops from polychromatophilic erythroblast [Term] id: CL:0000553 @@ -4836,6 +4947,7 @@ xref: CALOHA:TS-0610 xref: FMA:84235 is_a: CL:0000763 ! myeloid cell is_a: CL:0000839 ! myeloid lineage restricted progenitor cell +relationship: RO:0002202 CL:0000050 ! develops from megakaryocyte-erythroid progenitor cell [Term] id: CL:0000554 @@ -4864,6 +4976,8 @@ xref: CALOHA:TS-0611 xref: FMA:83555 is_a: CL:0000763 ! myeloid cell is_a: CL:1001610 ! bone marrow hematopoietic cell +disjoint_from: CL:0000764 ! erythroid lineage cell +relationship: RO:0002202 CL:0000553 ! develops from megakaryocyte progenitor cell [Term] id: CL:0000557 @@ -4891,6 +5005,7 @@ def: "An immature erythrocyte that changes the protein composition of its plasma xref: BTO:0001173 xref: CALOHA:TS-0864 is_a: CL:0000764 ! erythroid lineage cell +relationship: RO:0002202 CL:0000552 ! develops from orthochromatic erythroblast [Term] id: CL:0000559 @@ -4902,6 +5017,7 @@ xref: BTO:0004657 xref: FMA:83551 is_a: CL:0000763 ! myeloid cell is_a: CL:0002194 ! monopoietic cell +relationship: RO:0002202 CL:0000040 ! develops from monoblast [Term] id: CL:0000560 @@ -4915,6 +5031,7 @@ synonym: "band form" BROAD [] synonym: "rod neutrophil" EXACT [] synonym: "stab cell" BROAD [] is_a: CL:0000096 ! mature neutrophil +relationship: RO:0002202 CL:0000582 ! develops from neutrophilic metamyelocyte [Term] id: CL:0000561 @@ -4937,6 +5054,7 @@ synonym: "RBC" BROAD [] synonym: "red blood cell" BROAD [] is_a: CL:0000232 ! erythrocyte is_a: CL:0002242 ! nucleate cell +relationship: RO:0002202 CL:0002421 ! develops from nucleated reticulocyte [Term] id: CL:0000563 @@ -4958,6 +5076,7 @@ synonym: "neutrophilic progranulocyte" EXACT [] xref: FMA:84196 is_a: CL:0000834 ! neutrophil progenitor cell is_a: CL:0000836 ! promyelocyte +relationship: RO:0002202 CL:0000042 ! develops from neutrophilic myeloblast [Term] id: CL:0000565 @@ -4975,6 +5094,7 @@ comment: These cells are reportedly CD31-positive, CD34-positive, CD144-positive synonym: "angioblast" EXACT [] synonym: "chondroplast" EXACT [] is_a: CL:0000134 ! mesenchymal stem cell +relationship: RO:0002202 CL:0000134 ! develops from mesenchymal stem cell [Term] id: CL:0000567 @@ -5014,6 +5134,7 @@ xref: SCTID:176770005 is_a: CL:0000443 ! calcitonin secreting cell is_a: CL:0000458 ! serotonin secreting cell is_a: CL:0000710 ! neurecto-epithelial cell +relationship: RO:0002202 CL:0000333 ! develops from migratory neural crest cell [Term] id: CL:0000571 @@ -5021,6 +5142,7 @@ name: leucophore namespace: cell def: "A pigment cell derived from the neural crest. Contains uric acid or other purine crystals deposited in stacks called leucosomes. The crystals reflect light and this gives a white appearance under white light." [SANBI:mhl] is_a: CL:0000147 ! pigment cell +relationship: RO:0002202 CL:0005003 ! develops from leucoblast [Term] id: CL:0000573 @@ -5031,6 +5153,7 @@ xref: BTO:0001036 xref: CALOHA:TS-0866 xref: FMA:67748 is_a: CL:0010009 ! camera-type eye photoreceptor cell +relationship: RO:0002202 CL:0002672 ! develops from retinal progenitor cell [Term] id: CL:0000574 @@ -5038,6 +5161,7 @@ name: erythrophore namespace: cell def: "A pigment cell derived from the neural crest. Contains pteridine and/or carotenoid pigments in structures called pterinosomes or erythrosomes. This gives an orange to red appearance." [SANBI:mhl] is_a: CL:0000147 ! pigment cell +relationship: RO:0002202 CL:0005004 ! develops from pigment erythroblast [Term] id: CL:0000575 @@ -5064,6 +5188,7 @@ xref: FMA:62864 is_a: CL:0000766 ! myeloid leukocyte is_a: CL:0000842 ! mononuclear cell is_a: CL:0011115 ! precursor cell +relationship: RO:0002202 CL:0000559 ! develops from promonocyte [Term] id: CL:0000577 @@ -5129,6 +5254,7 @@ synonym: "juvenile neutrophil" EXACT [] xref: FMA:84197 is_a: CL:0000776 ! immature neutrophil is_a: CL:0002192 ! metamyelocyte +relationship: RO:0002202 CL:0000580 ! develops from neutrophilic myelocyte [Term] id: CL:0000583 @@ -5208,6 +5334,7 @@ synonym: "theca lutein cell" EXACT [] xref: BTO:0002850 xref: FMA:18690 is_a: CL:0000175 ! luteal cell +relationship: RO:0002202 CL:0000503 ! develops from theca cell [Term] id: CL:0000591 @@ -5226,6 +5353,7 @@ synonym: "granulosoluteocytus" RELATED [] xref: FMA:18689 is_a: CL:0000175 ! luteal cell is_a: CL:0000177 ! testosterone secreting cell +relationship: RO:0002202 CL:0000501 ! develops from granulosa cell [Term] id: CL:0000593 @@ -5252,6 +5380,7 @@ synonym: "RBC" BROAD [] synonym: "red blood cell" BROAD [] is_a: CL:0000225 ! anucleate cell is_a: CL:0000232 ! erythrocyte +relationship: RO:0002202 CL:0002422 ! develops from enucleated reticulocyte [Term] id: CL:0000596 @@ -5335,6 +5464,7 @@ xref: BTO:0001024 xref: CALOHA:TS-0870 xref: FMA:67747 is_a: CL:0010009 ! camera-type eye photoreceptor cell +relationship: RO:0002202 CL:0002672 ! develops from retinal progenitor cell [Term] id: CL:0000605 @@ -5397,6 +5527,7 @@ synonym: "EoP" EXACT [PMCID:PMC2212039, PMCID:PMC2626675] synonym: "eosinophil stem cell" RELATED [] is_a: CL:0000763 ! myeloid cell is_a: CL:0002191 ! granulocytopoietic cell +relationship: RO:0002202 CL:0000557 ! develops from granulocyte monocyte progenitor cell [Term] id: CL:0000612 @@ -5421,6 +5552,7 @@ synonym: "CFU-Bas" RELATED [] synonym: "colony forming unit basophil" RELATED [] is_a: CL:0000763 ! myeloid cell is_a: CL:0002191 ! granulocytopoietic cell +relationship: RO:0002202 CL:0002028 ! develops from basophil mast progenitor cell [Term] id: CL:0000614 @@ -5513,6 +5645,7 @@ xref: FMA:63147 xref: FMA:83601 xref: VHOG:0001697 is_a: CL:0001067 ! group 1 innate lymphoid cell +relationship: RO:0002202 CL:0000825 ! develops from pro-NK cell [Term] id: CL:0000624 @@ -5523,6 +5656,7 @@ synonym: "CD4-positive, alpha-beta T lymphocyte" EXACT [] synonym: "CD4-positive, alpha-beta T-cell" EXACT [] synonym: "CD4-positive, alpha-beta T-lymphocyte" EXACT [] is_a: CL:0000791 ! mature alpha-beta T cell +disjoint_from: CL:0000625 ! CD8-positive, alpha-beta T cell [Term] id: CL:0000625 @@ -5646,6 +5780,7 @@ xref: FMA:83089 is_a: CL:0000150 ! glandular epithelial cell is_a: CL:0000166 ! chromaffin cell is_a: CL:0000167 ! peptide hormone secreting cell +is_a: CL:0002319 ! neural cell is_a: CL:2000004 ! pituitary gland cell [Term] @@ -5731,6 +5866,7 @@ xref: BTO:0003107 xref: FMA:83035 is_a: CL:0000228 ! multinucleate cell is_a: CL:0000766 ! myeloid leukocyte +relationship: RO:0002202 CL:0000235 ! develops from macrophage [Term] id: CL:0000648 @@ -5767,6 +5903,7 @@ xref: BTO:0000853 xref: CALOHA:TS-0617 xref: FMA:70972 is_a: CL:0000669 ! pericyte cell +relationship: RO:0002202 CL:0000134 ! develops from mesenchymal stem cell [Term] id: CL:0000651 @@ -5810,6 +5947,7 @@ synonym: "primary oogonium" RELATED [] xref: BTO:0000512 xref: FMA:18645 is_a: CL:0000023 ! oocyte +relationship: RO:0002202 CL:0000024 ! develops from oogonial cell [Term] id: CL:0000655 @@ -5820,6 +5958,7 @@ synonym: "primary oogonium" RELATED [] xref: BTO:0003094 xref: FMA:18646 is_a: CL:0000023 ! oocyte +relationship: RO:0002202 CL:0000654 ! develops from primary oocyte [Term] id: CL:0000656 @@ -5842,6 +5981,7 @@ xref: FBbt:00004941 xref: FMA:72293 is_a: CL:0000017 ! spermatocyte is_a: CL:0000413 ! haploid cell +relationship: RO:0002202 CL:0000656 ! develops from primary spermatocyte [Term] id: CL:0000658 @@ -6024,6 +6164,7 @@ namespace: cell def: "A non-terminally differentiated cell that is capable of developing into a muscle cell." [GOC:add] is_a: CL:0000055 ! non-terminally differentiated cell is_a: CL:0002371 ! somatic cell +relationship: RO:0002202 CL:0000222 ! develops from mesodermal cell [Term] id: CL:0000681 @@ -6033,6 +6174,7 @@ def: "A cell present in the developing CNS. Functions as both a precursor cell a comment: Unlike that of mammals, the brain of adult teleost fish exhibits an intense and widespread neurogenic activity as a result of the persistence of\nradial glial cells acting as neural progenitors throughout life. synonym: "forebrain radial glial cell" NARROW [] is_a: CL:0000243 ! glial cell (sensu Vertebrata) +relationship: RO:0002202 CL:0000710 ! develops from neurecto-epithelial cell [Term] id: CL:0000682 @@ -6078,6 +6220,7 @@ namespace: cell def: "A columnar/cuboidal epithelial cell that secretes cerebrospinal fluid." [GOC:tfm] is_a: CL:0000151 ! secretory cell is_a: CL:0000710 ! neurecto-epithelial cell +relationship: RO:0002202 CL:0000333 ! develops from migratory neural crest cell [Term] id: CL:0000687 @@ -6278,6 +6421,7 @@ xref: BTO:0004301 xref: FMA:70557 is_a: CL:0000075 ! columnar/cuboidal epithelial cell is_a: CL:0002077 ! ecto-epithelial cell +relationship: RO:0002202 CL:0000133 ! develops from neurectodermal cell [Term] id: CL:0000711 @@ -6287,6 +6431,7 @@ def: "Cumulus cell is a specialized granulosa cell that surrounds and nourishes xref: BTO:0002236 is_a: CL:0000154 ! protein secreting cell is_a: CL:0002174 ! follicular cell of ovary +relationship: RO:0002202 CL:0000501 ! develops from granulosa cell [Term] id: CL:0000712 @@ -6366,7 +6511,7 @@ is_a: CL:0002371 ! somatic cell id: CL:0000724 name: heterocyst namespace: cell -def: " A differentiated cell that functions as a site of nitrogen fixation under aerobic conditions." [MA:ma] +def: "A differentiated cell that functions as a site of nitrogen fixation under aerobic conditions." [MA:ma] xref: BTO:0000600 is_a: CL:0000520 ! prokaryotic cell is_a: CL:0000725 ! nitrogen fixing cell @@ -6463,6 +6608,7 @@ xref: BTO:0002916 xref: CALOHA:TS-2157 xref: FMA:86936 is_a: CL:0000187 ! muscle cell +disjoint_from: CL:0008000 ! non-striated muscle cell [Term] id: CL:0000738 @@ -6477,6 +6623,7 @@ xref: CALOHA:TS-0549 xref: FMA:62852 is_a: CL:0000219 ! motile cell is_a: CL:0000988 ! hematopoietic cell +relationship: RO:0002202 CL:0000037 ! develops from hematopoietic stem cell [Term] id: CL:0000740 @@ -6548,6 +6695,7 @@ xref: CALOHA:TS-0115 xref: FMA:14067 is_a: CL:0000737 ! striated muscle cell is_a: CL:0002494 ! cardiocyte +relationship: RO:0002202 CL:0000513 ! develops from cardiac muscle myoblast [Term] id: CL:0000747 @@ -6556,13 +6704,16 @@ namespace: cell def: "A pigment cell derived from the neural crest. Contains blue pigment of unknown chemical composition in fibrous organelles termed cyanosomes. This gives a blue appearance." [SANBI:mhl] synonym: "blue chromatophore" RELATED [] is_a: CL:0000147 ! pigment cell +relationship: RO:0002202 CL:0005005 ! develops from cyanoblast [Term] id: CL:0000748 name: retinal bipolar neuron -namespace: cell def: "A bipolar neuron found in the retina and having connections with photoreceptors cells and neurons in the inner plexiform layer." [PMID:14689473] is_a: CL:0000103 ! bipolar neuron +is_a: CL:0000679 ! glutamatergic neuron +is_a: CL:0008028 ! visual system neuron +is_a: CL:0008030 ! excitatory neuron is_a: CL:0009004 ! retinal cell [Term] @@ -6576,16 +6727,16 @@ is_a: CL:0000748 ! retinal bipolar neuron id: CL:0000750 name: OFF-bipolar cell namespace: cell -def: "A bipolar neuron found in the retina and having connections with photoreceptors cells and neurons in the outer half of the inner plexiform layer. These cells hyperpolarize in response to light stimulation of their corresponding photoreceptors." [PMID:14689473] +def: "A bipolar neuron found in the retina and having connections with photoreceptors cells and neurons in the outer half of the inner plexiform layer. These cells depolatize in response to light to dark transition." [PMID:14689473] is_a: CL:0000748 ! retinal bipolar neuron [Term] id: CL:0000751 name: rod bipolar cell namespace: cell -def: "A bipolar neuron found in the retina and having connections with rod photoreceptor cells and neurons in the inner plexiform layer." [GOC:tfm, PMID:14689473] +def: "A bipolar neuron found in the retina that is synapsed by rod photoreceptor cells but not by cone photoreceptor cells. These neurons depolarize in response to light." [GOC:tfm, PMID:14689473] xref: FMA:67750 -is_a: CL:0000749 ! ON-bipolar cell +is_a: CL:0000748 ! retinal bipolar neuron [Term] id: CL:0000752 @@ -6597,19 +6748,16 @@ is_a: CL:0000748 ! retinal bipolar neuron [Term] id: CL:0000753 name: type 1 cone bipolar cell (sensu Mus) -namespace: cell def: "An OFF-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the outer half of the inner plexiform layer. The cell body of these cells is in the middle of the inner plexiform layer. The dendritic tree is stout and the axon terminates in sublamina 1. The axonal terminal is wide and has only a few varicosities." [PMID:14689473] synonym: "DB1 cone bipolar cell" EXACT [] -is_a: CL:0000750 ! OFF-bipolar cell is_a: CL:0000752 ! cone retinal bipolar cell [Term] id: CL:0000754 name: type 2 cone bipolar cell (sensu Mus) namespace: cell -def: "An OFF-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the outer half of the inner plexiform layer. The dendritic tree is not well filled and the dendrites are more delicate than in type 1 cells. The axon terminal is bushier and exhibits a dense plexus of varicosities in the inner part of sublamina 1." [PMID:14689473] +def: "An OFF-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the outer half of the inner plexiform layer. The dendritic tree is not well filled and the dendrites are more delicate than in type 1 cells. The axon terminal is bushier and exhibits a dense plexus of varicosities in the inner part of sublamina 1 (Ghosh et al., 2004). It can be differentiated from other retinal bipolar neurons by its expression of marker genes: Neto1, Lhx3 and Irx-6 (Shekhar, 2016)." [PMID:14689473, PMID:27565351] synonym: "FMB cone bipolar cell" EXACT [] -is_a: CL:0000750 ! OFF-bipolar cell is_a: CL:0000752 ! cone retinal bipolar cell [Term] @@ -6618,7 +6766,6 @@ name: type 3 cone bipolar cell (sensu Mus) namespace: cell def: "An OFF-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the outer half of the inner plexiform layer. The dendritic tree is delicate and the dendritic tips appear small when compared with type 1 cells. The axon terminal is stratified and restricted to sublamina 2 of the inner plexiform layer." [PMID:14689473] synonym: "DB2 cone bipolar cell" EXACT [] -is_a: CL:0000750 ! OFF-bipolar cell is_a: CL:0000752 ! cone retinal bipolar cell [Term] @@ -6627,7 +6774,6 @@ name: type 4 cone bipolar cell (sensu Mus) namespace: cell def: "An OFF-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the outer half of the inner plexiform layer. The cell has a diffuse axon terminal with varicosities in sublaminae 1 and 2 of the inner plexiform layer." [PMID:14689473] synonym: "DB3 cone bipolar cell" EXACT [] -is_a: CL:0000750 ! OFF-bipolar cell is_a: CL:0000752 ! cone retinal bipolar cell [Term] @@ -6636,7 +6782,6 @@ name: type 5 cone bipolar cell (sensu Mus) namespace: cell def: "An ON-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the inner half of the inner plexiform layer. The axon terminal is restricted to sublamina 3 of the inner plexiform layer. It is narrowly stratified and branched. The dendritic tree has many delicate branches." [PMID:14689473] synonym: "DB4 cone bipolar cell" EXACT [] -is_a: CL:0000749 ! ON-bipolar cell is_a: CL:0000752 ! cone retinal bipolar cell [Term] @@ -6645,7 +6790,6 @@ name: type 6 cone bipolar cell (sensu Mus) namespace: cell def: "An ON-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the inner half of the inner plexiform layer. The cell has a loose, delicate axon terminal that opens in sublamina 3 of the inner plexiform layer and descends into sublamina 4." [PMID:14689473] synonym: "DB5 cone bipolar cell" EXACT [] -is_a: CL:0000749 ! ON-bipolar cell is_a: CL:0000752 ! cone retinal bipolar cell [Term] @@ -6654,7 +6798,6 @@ name: type 7 cone bipolar cell (sensu Mus) namespace: cell def: "An ON-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the inner half of the inner plexiform layer. The axon terminal is narrowly stratified and are found just below a calretinin-expressing band in sublamina 4 of the inner plexiform layer." [PMID:14689473] synonym: "IMB cone bipolar cell" EXACT [] -is_a: CL:0000749 ! ON-bipolar cell is_a: CL:0000752 ! cone retinal bipolar cell [Term] @@ -6663,7 +6806,6 @@ name: type 8 cone bipolar cell (sensu Mus) namespace: cell def: "An ON-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the inner half of the inner plexiform layer. This cell has the widest dendritic field and the widest axon terminal of all retinal bipolar cells. The axon terminal is delicate and stratified through sublaminae 4 and 5 of the inner plexiform layer." [PMID:14689473] synonym: "DB6 cone bipolar cell" EXACT [] -is_a: CL:0000749 ! ON-bipolar cell is_a: CL:0000752 ! cone retinal bipolar cell [Term] @@ -6672,7 +6814,6 @@ name: type 9 cone bipolar cell (sensu Mus) namespace: cell def: "An ON-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the inner half of the inner plexiform layer. The dendritic tree is wide and the dendritic convergence indicates cone selectivity. The axon terminal is sparsely branched and terminates in sublamina 5 of the inner plexiform layer." [PMID:14689473] synonym: "BB cone bipolar cell" EXACT [] -is_a: CL:0000749 ! ON-bipolar cell is_a: CL:0000752 ! cone retinal bipolar cell [Term] @@ -6683,6 +6824,7 @@ def: "A nucleated blood cell involved in coagulation, typically seen in birds an comment: Note that this is a non-mammalian cell type. Use platelet ; CL:0000233 for thrombocytes (platelets) in mammals. is_a: CL:0000226 ! single nucleate cell is_a: CL:0000763 ! myeloid cell +relationship: RO:0002202 CL:0000828 ! develops from thromboblast [Term] id: CL:0000763 @@ -6692,6 +6834,7 @@ def: "A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroi xref: BTO:0001441 xref: CALOHA:TS-0647 is_a: CL:0000988 ! hematopoietic cell +relationship: RO:0002202 CL:0000049 ! develops from common myeloid progenitor [Term] id: CL:0000764 @@ -6718,6 +6861,7 @@ xref: FMA:83504 is_a: CL:0000764 ! erythroid lineage cell is_a: CL:0002242 ! nucleate cell is_a: CL:0011115 ! precursor cell +relationship: RO:0002202 CL:0000547 ! develops from proerythroblast [Term] id: CL:0000766 @@ -6751,6 +6895,7 @@ synonym: "immature basophilic leucocyte" EXACT [] synonym: "immature basophilic leukocyte" EXACT [] is_a: CL:0000767 ! basophil is_a: CL:0002242 ! nucleate cell +relationship: RO:0002202 CL:0000830 ! develops from basophilic promyelocyte [Term] id: CL:0000769 @@ -6760,6 +6905,7 @@ def: "A basophil precursor in the granulocytic series, being a cell intermediate xref: FMA:84198 is_a: CL:0000768 ! immature basophil is_a: CL:0002192 ! metamyelocyte +relationship: RO:0002202 CL:0000614 ! develops from basophilic myelocyte [Term] id: CL:0000770 @@ -6767,6 +6913,7 @@ name: band form basophil namespace: cell def: "A late basophilic metamyelocyte in which the nucleus is in the form of a curved or coiled band, not having acquired the typical multilobar shape of the mature basophil." [GOC:add, http://www.cap.org, ISBN:0721601464, PMID:18466030] is_a: CL:0000768 ! immature basophil +relationship: RO:0002202 CL:0000769 ! develops from basophilic metamyelocyte [Term] id: CL:0000771 @@ -6795,6 +6942,7 @@ synonym: "immature eosinophilic leucocyte" EXACT [] synonym: "immature eosinophilic leukocyte" EXACT [] is_a: CL:0000771 ! eosinophil is_a: CL:0002242 ! nucleate cell +relationship: RO:0002202 CL:0000833 ! develops from eosinophilic promyelocyte [Term] id: CL:0000773 @@ -6803,6 +6951,7 @@ namespace: cell def: "A eosinophil precursor in the granulocytic series, being a cell intermediate in development between a eosinophilic myelocyte and a band form eosinophil. The nucleus becomes indented where the indentation is smaller than half the distance to the farthest nuclear margin; chromatin becomes coarse and clumped; specific granules predominate while primary granules are rare. Markers are integrin alpha-M-positive, fucosyltransferase FUT4-positive, low affinity immunoglobulin gamma Fc region receptor III-positive, CD33-positive, CD24-positive and aminopeptidase N-negative." [GOC:add, GOC:tfm, ISBN:0721601464, PMID:19622087] is_a: CL:0000772 ! immature eosinophil is_a: CL:0002192 ! metamyelocyte +relationship: RO:0002202 CL:0000612 ! develops from eosinophilic myelocyte [Term] id: CL:0000774 @@ -6810,6 +6959,7 @@ name: band form eosinophil namespace: cell def: "A late eosinophilic metamyelocyte in which the nucleus is in the form of a curved or coiled band, not having acquired the typical multilobar shape of the mature basophil." [GOC:add, GOC:tfm, http://www.cap.org, ISBN:0721601464, PMID:19622087] is_a: CL:0000772 ! immature eosinophil +relationship: RO:0002202 CL:0000773 ! develops from eosinophilic metamyelocyte [Term] id: CL:0000775 @@ -6845,6 +6995,7 @@ synonym: "immature neutrophil leukocyte" EXACT [] synonym: "immature neutrophilic leucocyte" EXACT [] is_a: CL:0000775 ! neutrophil is_a: CL:0002242 ! nucleate cell +relationship: RO:0002202 CL:0000564 ! develops from neutrophilic promyelocyte [Term] id: CL:0000777 @@ -6872,6 +7023,7 @@ comment: Morphology: multinucleated, highly vesicular. synonym: "multinucleated osteoclast" EXACT [] is_a: CL:0000092 ! osteoclast is_a: CL:0000228 ! multinucleate cell +relationship: RO:0002202 CL:0000778 ! develops from mononuclear osteoclast [Term] id: CL:0000780 @@ -6882,6 +7034,7 @@ comment: Morphology: multinucleated, highly vesicular; location: roots of decidu synonym: "multinucleated odontoclast" EXACT [] is_a: CL:0000588 ! odontoclast is_a: CL:0000779 ! multinuclear osteoclast +relationship: RO:0002202 CL:0000781 ! develops from mononuclear odontoclast [Term] id: CL:0000781 @@ -6905,6 +7058,7 @@ synonym: "veiled cell" BROAD [] xref: BTO:0004721 is_a: CL:0000766 ! myeloid leukocyte is_a: CL:0000990 ! conventional dendritic cell +relationship: RO:0002202 CL:0000576 ! develops from monocyte [Term] id: CL:0000783 @@ -6941,6 +7095,10 @@ synonym: "mature B lymphocyte" EXACT [] synonym: "mature B-cell" EXACT [] synonym: "mature B-lymphocyte" EXACT [] is_a: CL:0000236 ! B cell +disjoint_from: CL:0000816 ! immature B cell +disjoint_from: CL:0000817 ! precursor B cell +disjoint_from: CL:0000818 ! transitional stage B cell +relationship: RO:0002202 CL:0000818 ! develops from transitional stage B cell [Term] id: CL:0000786 @@ -6957,6 +7115,7 @@ synonym: "plasmocyte" EXACT [] xref: BTO:0000392 xref: FMA:70574 is_a: CL:0000946 ! antibody secreting cell +relationship: RO:0002202 CL:0000980 ! develops from plasmablast [Term] id: CL:0000787 @@ -6989,6 +7148,7 @@ synonym: "alpha-beta T lymphocyte" EXACT [] synonym: "alpha-beta T-cell" EXACT [] synonym: "alpha-beta T-lymphocyte" EXACT [] is_a: CL:0000084 ! T cell +disjoint_from: CL:0000798 ! gamma-delta T cell [Term] id: CL:0000790 @@ -7011,6 +7171,7 @@ synonym: "mature alpha-beta T-cell" EXACT [] synonym: "mature alpha-beta T-lymphocyte" EXACT [] is_a: CL:0000789 ! alpha-beta T cell is_a: CL:0002419 ! mature T cell +relationship: RO:0002202 CL:0000790 ! develops from immature alpha-beta T cell [Term] id: CL:0000792 @@ -7041,6 +7202,7 @@ synonym: "IEL" BROAD [] synonym: "intraepithelial lymphocyte" BROAD [] is_a: CL:0000624 ! CD4-positive, alpha-beta T cell is_a: CL:0000797 ! alpha-beta intraepithelial T cell +relationship: RO:0002202 CL:0000810 ! develops from CD4-positive, alpha-beta thymocyte [Term] id: CL:0000794 @@ -7063,6 +7225,7 @@ xref: CALOHA:TS-0190 xref: FMA:70573 is_a: CL:0000625 ! CD8-positive, alpha-beta T cell is_a: CL:0000910 ! cytotoxic T cell +relationship: RO:0002202 CL:0000906 ! develops from activated CD8-positive, alpha-beta T cell [Term] id: CL:0000795 @@ -7134,6 +7297,7 @@ synonym: "immature gamma-delta T-cell" EXACT [] synonym: "immature gamma-delta T-lymphocyte" EXACT [] is_a: CL:0000798 ! gamma-delta T cell is_a: CL:0002420 ! immature T cell +relationship: RO:0002202 CL:0000807 ! develops from DN3 thymocyte [Term] id: CL:0000800 @@ -7145,6 +7309,7 @@ synonym: "mature gamma-delta T-cell" EXACT [] synonym: "mature gamma-delta T-lymphocyte" EXACT [] is_a: CL:0000798 ! gamma-delta T cell is_a: CL:0002419 ! mature T cell +relationship: RO:0002202 CL:0000799 ! develops from immature gamma-delta T cell [Term] id: CL:0000801 @@ -7195,6 +7360,7 @@ synonym: "immature single positive T-lymphocyte" EXACT [] synonym: "ISP" EXACT [] synonym: "T.ISP.th" EXACT [] is_a: CL:0000893 ! thymocyte +relationship: RO:0002202 CL:0000808 ! develops from DN4 thymocyte [Term] id: CL:0000806 @@ -7212,6 +7378,7 @@ synonym: "preT.DN2.Th" EXACT [] synonym: "TN2 cell" EXACT [] synonym: "TN2 thymocyte" EXACT [] is_a: CL:0002489 ! double negative thymocyte +relationship: RO:0002202 CL:0000894 ! develops from DN1 thymic pro-T cell [Term] id: CL:0000807 @@ -7229,6 +7396,7 @@ synonym: "preT.DN3.Th" EXACT [] synonym: "TN3 cell" EXACT [] synonym: "TN3 thymocyte" EXACT [] is_a: CL:0002489 ! double negative thymocyte +relationship: RO:0002202 CL:0000806 ! develops from DN2 thymocyte [Term] id: CL:0000808 @@ -7245,6 +7413,7 @@ synonym: "double negative 4" EXACT [] synonym: "early cortical thymocyte" BROAD [] synonym: "T.DN4.th" EXACT [] is_a: CL:0002489 ! double negative thymocyte +relationship: RO:0002202 CL:0000807 ! develops from DN3 thymocyte [Term] id: CL:0000809 @@ -7258,6 +7427,7 @@ synonym: "DP thymocyte" EXACT [] synonym: "late cortical thymocyte" BROAD [] is_a: CL:0000790 ! immature alpha-beta T cell is_a: CL:0000893 ! thymocyte +relationship: RO:0002202 CL:0000805 ! develops from immature single positive thymocyte [Term] id: CL:0000810 @@ -7270,6 +7440,7 @@ synonym: "CD4-positive, alpha-beta immature T-lymphocyte" EXACT [] synonym: "SP CD4 cell" EXACT [] is_a: CL:0000790 ! immature alpha-beta T cell is_a: CL:0000893 ! thymocyte +relationship: RO:0002202 CL:0000809 ! develops from double-positive, alpha-beta thymocyte [Term] id: CL:0000811 @@ -7283,6 +7454,7 @@ synonym: "CD8-positive, alpha-beta immature T-lymphocyte" EXACT [] synonym: "SP CD8 cell" EXACT [] is_a: CL:0000790 ! immature alpha-beta T cell is_a: CL:0000893 ! thymocyte +relationship: RO:0002202 CL:0000809 ! develops from double-positive, alpha-beta thymocyte [Term] id: CL:0000813 @@ -7294,6 +7466,7 @@ synonym: "memory T-cell" EXACT [] synonym: "memory T-lymphocyte" EXACT [] xref: BTO:0003435 is_a: CL:0002419 ! mature T cell +disjoint_from: CL:0000898 ! naive T cell [Term] id: CL:0000814 @@ -7310,6 +7483,7 @@ synonym: "mature NK T-lymphocyte" EXACT [] synonym: "mature NKT cell" EXACT [] is_a: CL:0000791 ! mature alpha-beta T cell is_a: CL:0002127 ! innate effector T cell +relationship: RO:0002202 CL:0002042 ! develops from immature NK T cell stage IV [Term] id: CL:0000815 @@ -7339,6 +7513,7 @@ synonym: "immature B-cell" EXACT [] synonym: "immature B-lymphocyte" EXACT [] synonym: "newly formed B cell" EXACT [ISBN:781735149] is_a: CL:0000236 ! B cell +relationship: RO:0002202 CL:0000954 ! develops from small pre-B-II cell [Term] id: CL:0000817 @@ -7349,6 +7524,7 @@ synonym: "pre-B cell" RELATED [] xref: BTO:0001133 xref: CALOHA:TS-0819 is_a: CL:0000236 ! B cell +disjoint_from: CL:0000826 ! pro-B cell [Term] id: CL:0000818 @@ -7364,6 +7540,7 @@ synonym: "transitional stage B lymphocyte" EXACT [] synonym: "transitional stage B-cell" EXACT [] synonym: "transitional stage B-lymphocyte" EXACT [] is_a: CL:0000236 ! B cell +relationship: RO:0002202 CL:0000816 ! develops from immature B cell [Term] id: CL:0000819 @@ -7441,6 +7618,9 @@ comment: In mouse the NKR are Ly49 molecules and in human these cells express KI synonym: "immature NK cell" EXACT [] synonym: "p-NK" RELATED [PMID:12457618] is_a: CL:0000623 ! natural killer cell +disjoint_from: CL:0000824 ! mature natural killer cell +disjoint_from: CL:0000937 ! pre-natural killer cell +relationship: RO:0002202 CL:0000937 ! develops from pre-natural killer cell [Term] id: CL:0000824 @@ -7451,6 +7631,9 @@ synonym: "LAK cell" BROAD [PMID:14685782] synonym: "lymphokine activated killer cell" BROAD [PMID:14685782] synonym: "mature NK cell" EXACT [] is_a: CL:0000623 ! natural killer cell +disjoint_from: CL:0002338 ! CD56-positive, CD161-positive immature natural killer cell +disjoint_from: CL:0002344 ! CD56-negative, CD161-positive immature natural killer cell +relationship: RO:0002202 CL:0000823 ! develops from immature natural killer cell [Term] id: CL:0000825 @@ -7464,6 +7647,7 @@ synonym: "null cell" RELATED [PMID:11532393] synonym: "preNK cell" RELATED [PMID:11532393] synonym: "pro-natural killer cell" EXACT [] is_a: CL:0000838 ! lymphoid lineage restricted progenitor cell +relationship: RO:0002202 CL:0000051 ! develops from common lymphoid progenitor [Term] id: CL:0000826 @@ -7482,6 +7666,7 @@ synonym: "progenitor B-cell" EXACT [] synonym: "progenitor B-lymphocyte" EXACT [] xref: BTO:0003104 is_a: CL:0000838 ! lymphoid lineage restricted progenitor cell +relationship: RO:0002202 CL:0000051 ! develops from common lymphoid progenitor [Term] id: CL:0000827 @@ -7494,6 +7679,7 @@ synonym: "pro-T lymphocyte" EXACT [] synonym: "progenitor T cell" EXACT [] synonym: "TN1 cell" NARROW [] is_a: CL:0000838 ! lymphoid lineage restricted progenitor cell +relationship: RO:0002202 CL:0000051 ! develops from common lymphoid progenitor [Term] id: CL:0000828 @@ -7504,6 +7690,7 @@ comment: Note that this is a non-mammalian cell type. is_a: CL:0000226 ! single nucleate cell is_a: CL:0000763 ! myeloid cell is_a: CL:0000839 ! myeloid lineage restricted progenitor cell +relationship: RO:0002202 CL:0000050 ! develops from megakaryocyte-erythroid progenitor cell [Term] id: CL:0000829 @@ -7511,6 +7698,7 @@ name: basophilic myeloblast namespace: cell def: "A myeloblast committed to the basophil lineage." [GOC:add, ISBN:0721601464] is_a: CL:0000835 ! myeloblast +relationship: RO:0002202 CL:0000613 ! develops from basophil progenitor cell [Term] id: CL:0000830 @@ -7519,6 +7707,7 @@ namespace: cell def: "A promyelocyte committed to the basophil lineage." [GOC:add, ISBN:0721601464] xref: FMA:84208 is_a: CL:0000836 ! promyelocyte +relationship: RO:0002202 CL:0000829 ! develops from basophilic myeloblast [Term] id: CL:0000831 @@ -7526,12 +7715,13 @@ name: mast cell progenitor namespace: cell def: "A progenitor cell of the mast cell lineage. Markers for this cell are FceRIa-low, CD117-positive, CD9-positive, T1/ST2-positive, SCA1-negative, and lineage-negative." [GOC:add, GOC:dsd, http://www.copewithcytokines.de, PMCID:PMC1183570, PMCID:PMC1312421, PMID:8629001, PMID:9354811] comment: MCP are CD16-positive, CD32-positive, CD34-positive, CD45-positive, integrin beta-7-positive, and lin-negative (CD2, CD3e, CD4, CD5, CD8a, CD14, CD19, CD20, CD27, integrin alpha-M, ly6c, ly6g, NCAM-1, and ter119). These cells also express the transcription factors GATA-1, GATA-2, and MITF, but not C/EBPa. -synonym: "CFU-Mast " RELATED [] +synonym: "CFU-Mast" RELATED [] synonym: "CFU-MC" RELATED [] synonym: "colony forming unit mast cell" RELATED [] synonym: "MCP" EXACT [] is_a: CL:0000763 ! myeloid cell is_a: CL:0000839 ! myeloid lineage restricted progenitor cell +relationship: RO:0002202 CL:0002028 ! develops from basophil mast progenitor cell [Term] id: CL:0000832 @@ -7539,6 +7729,7 @@ name: eosinophilic myeloblast namespace: cell def: "A myeloblast committed to the eosinophil lineage." [GOC:add, ISBN:0721601464] is_a: CL:0000835 ! myeloblast +relationship: RO:0002202 CL:0000611 ! develops from eosinophil progenitor cell [Term] id: CL:0000833 @@ -7547,6 +7738,7 @@ namespace: cell def: "A promyelocyte committed to the eosinophil lineage." [GOC:add, ISBN:0721601464] xref: FMA:84199 is_a: CL:0000836 ! promyelocyte +relationship: RO:0002202 CL:0000832 ! develops from eosinophilic myeloblast [Term] id: CL:0000834 @@ -7556,6 +7748,7 @@ def: "A progenitor cell of the neutrophil lineage." [GOC:add, GOC:tfm, ISBN:0721 synonym: "neutrophil stem cell" RELATED [] is_a: CL:0000763 ! myeloid cell is_a: CL:0002191 ! granulocytopoietic cell +relationship: RO:0002202 CL:0000557 ! develops from granulocyte monocyte progenitor cell [Term] id: CL:0000835 @@ -7567,6 +7760,7 @@ xref: FMA:83524 is_a: CL:0000763 ! myeloid cell is_a: CL:0002191 ! granulocytopoietic cell is_a: CL:0002242 ! nucleate cell +relationship: RO:0002202 CL:0000557 ! develops from granulocyte monocyte progenitor cell [Term] id: CL:0000836 @@ -7578,6 +7772,7 @@ xref: FMA:83530 is_a: CL:0000763 ! myeloid cell is_a: CL:0002191 ! granulocytopoietic cell is_a: CL:0002242 ! nucleate cell +relationship: RO:0002202 CL:0000835 ! develops from myeloblast [Term] id: CL:0000837 @@ -7590,6 +7785,8 @@ synonym: "MPP" EXACT [] xref: BTO:0000725 xref: CALOHA:TS-0448 is_a: CL:0008001 ! hematopoietic precursor cell +disjoint_from: CL:0002032 ! hematopoietic oligopotent progenitor cell +relationship: RO:0002202 CL:0000037 ! develops from hematopoietic stem cell [Term] id: CL:0000838 @@ -7603,6 +7800,7 @@ xref: CALOHA:TS-2025 xref: FMA:70338 is_a: CL:0002031 ! hematopoietic lineage restricted progenitor cell is_a: CL:0011115 ! precursor cell +disjoint_from: CL:0000839 ! myeloid lineage restricted progenitor cell [Term] id: CL:0000839 @@ -7625,6 +7823,7 @@ def: "An immature cell of the conventional dendritic cell lineage, characterized synonym: "immature myeloid dendritic cell" NARROW [] is_a: CL:0000766 ! myeloid leukocyte is_a: CL:0000990 ! conventional dendritic cell +relationship: RO:0002202 CL:0001029 ! develops from common dendritic progenitor [Term] id: CL:0000841 @@ -7636,6 +7835,7 @@ synonym: "mature myeloid dendritic cell" NARROW [] xref: FMA:83038 is_a: CL:0000766 ! myeloid leukocyte is_a: CL:0000990 ! conventional dendritic cell +relationship: RO:0002202 CL:0000840 ! develops from immature conventional dendritic cell [Term] id: CL:0000842 @@ -7677,6 +7877,7 @@ synonym: "germinal center B lymphocyte" EXACT [] synonym: "germinal center B-cell" EXACT [] synonym: "germinal center B-lymphocyte" EXACT [] is_a: CL:0000785 ! mature B cell +relationship: RO:0002202 CL:0000843 ! develops from follicular B cell [Term] id: CL:0000845 @@ -7751,6 +7952,7 @@ name: neuromast mantle cell namespace: cell def: "Neuromast mantle cell is a non-sensory cell. Neuromast mantle cells surround the neuromast support cells and neuromast hair cells, separating the neuromast from the epidermis, and secrete cupula in which the ciliary bundles of all the hair cells are embedded." [ISBN:0125296509] is_a: CL:0000151 ! secretory cell +disjoint_from: CL:0000855 ! sensory hair cell [Term] id: CL:0000852 @@ -7758,6 +7960,7 @@ name: neuromast support cell namespace: cell def: "Neuromast support cell is a non-sensory cell of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; neuromast support cells are surrounded by neuromast mantle cells." [ISBN:0125296509] is_a: CL:0000630 ! supportive cell +disjoint_from: CL:0000855 ! sensory hair cell [Term] id: CL:0000853 @@ -7777,6 +7980,7 @@ name: interneuromast cell namespace: cell def: "Interneuromast cell is a neuroectodermal cell deposited by the migrating lateral line primordium between the neuromasts. Interneuromast cells proliferate and migrate to form additional neuromasts." [SANBI:mhl] is_a: CL:0000133 ! neurectodermal cell +relationship: RO:0002202 CL:0000032 ! develops from neuroplacodal cell [Term] id: CL:0000855 @@ -7829,6 +8033,7 @@ synonym: "wandering histiocyte" EXACT [] xref: FMA:84643 xref: FMA:84645 is_a: CL:0000235 ! macrophage +relationship: RO:0002202 CL:0000860 ! develops from classical monocyte [Term] id: CL:0000862 @@ -7947,6 +8152,7 @@ comment: Markers: CCR2-CX3CCR1+ (human, mouse, rat); human: CD16+, CCR5+, CD32/F synonym: "patrolling monocyte" EXACT [] synonym: "resident monocyte" EXACT [] is_a: CL:0000576 ! monocyte +relationship: RO:0002202 CL:0002393 ! develops from intermediate monocyte [Term] id: CL:0000876 @@ -8075,6 +8281,7 @@ name: smooth muscle cell derived foam cell namespace: cell def: "A type of foam cell derived from a smooth muscle cell containing lipids in small vacuoles and typically seen in atherolosclerotic lesions, as well as other conditions." [GOC:add] is_a: CL:0000891 ! foam cell +relationship: RO:0002202 CL:0000192 ! develops from smooth muscle cell [Term] id: CL:0000893 @@ -8105,6 +8312,7 @@ synonym: "DN1 thymocyte" EXACT [] synonym: "double negative 1" EXACT [] synonym: "preT.DN1.Th" EXACT [] is_a: CL:0000827 ! pro-T cell +relationship: RO:0002202 CL:0002425 ! develops from early T lineage precursor [Term] id: CL:0000895 @@ -8120,6 +8328,7 @@ synonym: "T.4Nve.Sp" EXACT [] synonym: "Th0" EXACT [GOC:tfm] is_a: CL:0000624 ! CD4-positive, alpha-beta T cell is_a: CL:0000898 ! naive T cell +relationship: RO:0002202 CL:0002436 ! develops from mature CD4 single-positive thymocyte [Term] id: CL:0000896 @@ -8130,6 +8339,7 @@ synonym: "activated CD4-positive, alpha-beta T lymphocyte" EXACT [] synonym: "activated CD4-positive, alpha-beta T-cell" EXACT [] synonym: "activated CD4-positive, alpha-beta T-lymphocyte" EXACT [] is_a: CL:0000624 ! CD4-positive, alpha-beta T cell +relationship: RO:0002202 CL:0000895 ! develops from naive thymus-derived CD4-positive, alpha-beta T cell [Term] id: CL:0000897 @@ -8142,6 +8352,7 @@ synonym: "CD4-positive, alpha-beta memory T-lymphocyte" EXACT [] synonym: "T4.Mem.Sp" RELATED [] is_a: CL:0000624 ! CD4-positive, alpha-beta T cell is_a: CL:0000813 ! memory T cell +relationship: RO:0002202 CL:0000896 ! develops from activated CD4-positive, alpha-beta T cell [Term] id: CL:0000898 @@ -8184,6 +8395,7 @@ synonym: "naive thymus-dervied CD8-positive, alpha-beta T-lymphocyte" EXACT [] synonym: "T.8Nve.Sp" NARROW [] is_a: CL:0000625 ! CD8-positive, alpha-beta T cell is_a: CL:0000898 ! naive T cell +relationship: RO:0002202 CL:0002437 ! develops from mature CD8 single-positive thymocyte [Term] id: CL:0000901 @@ -8213,6 +8425,7 @@ synonym: "induced regulatory T-lymphocyte" EXACT [] synonym: "induced Treg" EXACT [] synonym: "iTreg" EXACT [] is_a: CL:0000792 ! CD4-positive, CD25-positive, alpha-beta regulatory T cell +relationship: RO:0002202 CL:0000896 ! develops from activated CD4-positive, alpha-beta T cell [Term] id: CL:0000903 @@ -8226,6 +8439,7 @@ synonym: "natural regulatory T-lymphocyte" EXACT [] synonym: "natural Treg" EXACT [] synonym: "nTreg" EXACT [] is_a: CL:0000792 ! CD4-positive, CD25-positive, alpha-beta regulatory T cell +relationship: RO:0002202 CL:0000809 ! develops from double-positive, alpha-beta thymocyte [Term] id: CL:0000904 @@ -8268,6 +8482,7 @@ synonym: "activated CD8-positive, alpha-beta T lymphocyte" EXACT [] synonym: "activated CD8-positive, alpha-beta T-cell" EXACT [] synonym: "activated CD8-positive, alpha-beta T-lymphocyte" EXACT [] is_a: CL:0000625 ! CD8-positive, alpha-beta T cell +relationship: RO:0002202 CL:0000900 ! develops from naive thymus-derived CD8-positive, alpha-beta T cell [Term] id: CL:0000907 @@ -8295,6 +8510,7 @@ synonym: "CD8-positive, alpha-beta cytokine secreting effector T-cell" EXACT [] synonym: "CD8-positive, alpha-beta cytokine secreting effector T-lymphocyte" EXACT [] is_a: CL:0000625 ! CD8-positive, alpha-beta T cell is_a: CL:0000912 ! helper T cell +relationship: RO:0002202 CL:0000906 ! develops from activated CD8-positive, alpha-beta T cell [Term] id: CL:0000909 @@ -8307,6 +8523,7 @@ synonym: "CD8-positive, alpha-beta memory T-lymphocyte" EXACT [] synonym: "T.8Mem.Sp" EXACT [] is_a: CL:0000625 ! CD8-positive, alpha-beta T cell is_a: CL:0000813 ! memory T cell +relationship: RO:0002202 CL:0000906 ! develops from activated CD8-positive, alpha-beta T cell [Term] id: CL:0000910 @@ -8369,6 +8586,7 @@ synonym: "immature NK T-cell" EXACT [] synonym: "immature NK T-lymphocyte" EXACT [] synonym: "immature NKT cell" EXACT [] is_a: CL:0000790 ! immature alpha-beta T cell +relationship: RO:0002202 CL:0000809 ! develops from double-positive, alpha-beta thymocyte [Term] id: CL:0000915 @@ -8379,6 +8597,7 @@ synonym: "CD8-alpha-alpha-positive, alpha-beta intraepithelial T lymphocyte" EXA synonym: "CD8-alpha-alpha-positive, alpha-beta intraepithelial T-cell" EXACT [] synonym: "CD8-alpha-alpha-positive, alpha-beta intraepithelial T-lymphocyte" EXACT [] is_a: CL:0000797 ! alpha-beta intraepithelial T cell +relationship: RO:0002202 CL:0000811 ! develops from CD8-positive, alpha-beta thymocyte [Term] id: CL:0000916 @@ -8391,6 +8610,7 @@ synonym: "dendritic epidermal T-cell" EXACT [] synonym: "dendritic epidermal T-lymphocyte" EXACT [] synonym: "DETC" EXACT [] is_a: CL:0000800 ! mature gamma-delta T cell +relationship: RO:0002202 CL:0002401 ! develops from mature dendritic epithelial T cell precursor [Term] id: CL:0000917 @@ -8434,13 +8654,14 @@ synonym: "CD8+CD25+ T cell" EXACT [] synonym: "CD8+CD25+ T lymphocyte" EXACT [] synonym: "CD8+CD25+ T(reg)" EXACT [] synonym: "CD8+CD25+ T-cell" EXACT [] -synonym: "CD8+CD25+ T-lymphocyte " EXACT [] +synonym: "CD8+CD25+ T-lymphocyte" EXACT [] synonym: "CD8+CD25+ Treg" EXACT [] synonym: "CD8-positive, CD25-positive Treg" EXACT [] synonym: "CD8-positive, CD25-positive, alpha-beta regulatory T lymphocyte" EXACT [] synonym: "CD8-positive, CD25-positive, alpha-beta regulatory T-cell" EXACT [] synonym: "CD8-positive, CD25-positive, alpha-beta regulatory T-lymphocyte" EXACT [] is_a: CL:0000795 ! CD8-positive, alpha-beta regulatory T cell +relationship: RO:0002202 CL:0000906 ! develops from activated CD8-positive, alpha-beta T cell [Term] id: CL:0000920 @@ -8451,7 +8672,7 @@ synonym: "CD8+CD28- T cell" EXACT [] synonym: "CD8+CD28- T lymphocyte" EXACT [] synonym: "CD8+CD28- T(reg)" EXACT [] synonym: "CD8+CD28- T-cell" EXACT [] -synonym: "CD8+CD28- T-lymphocyte " EXACT [] +synonym: "CD8+CD28- T-lymphocyte" EXACT [] synonym: "CD8+CD28- Treg" EXACT [] synonym: "CD8-positive, CD28-negative T(reg)" EXACT [] synonym: "CD8-positive, CD28-negative Treg" EXACT [] @@ -8459,6 +8680,7 @@ synonym: "CD8-positive, CD28-negative, alpha-beta regulatory T lymphocyte" EXACT synonym: "CD8-positive, CD28-negative, alpha-beta regulatory T-cell" EXACT [] synonym: "CD8-positive, CD28-negative, alpha-beta regulatory T-lymphocyte" EXACT [] is_a: CL:0000795 ! CD8-positive, alpha-beta regulatory T cell +relationship: RO:0002202 CL:0000906 ! develops from activated CD8-positive, alpha-beta T cell [Term] id: CL:0000921 @@ -8520,6 +8742,7 @@ synonym: "activated CD4-positive type I NK T-lymphocyte" EXACT [] synonym: "activated CD4-positive type I NKT cell" EXACT [] is_a: CL:0000912 ! helper T cell is_a: CL:0000923 ! CD4-positive type I NK T cell +relationship: RO:0002202 CL:0000923 ! develops from CD4-positive type I NK T cell [Term] id: CL:0000926 @@ -8533,6 +8756,7 @@ synonym: "CD4-positive type I NK T-lymphocyte secreting interferon-gamma" EXACT synonym: "CD4-positive type I NKT cell secreting interferon-gamma" EXACT [] is_a: CL:0000912 ! helper T cell is_a: CL:0000923 ! CD4-positive type I NK T cell +relationship: RO:0002202 CL:0000925 ! develops from activated CD4-positive type I NK T cell [Term] id: CL:0000927 @@ -8546,6 +8770,7 @@ synonym: "CD4-positive type I NK T-lymphocyte secreting interleukin-4" EXACT [] synonym: "CD4-positive type I NKT cell secreting interleukin-4" EXACT [] is_a: CL:0000912 ! helper T cell is_a: CL:0000923 ! CD4-positive type I NK T cell +relationship: RO:0002202 CL:0000925 ! develops from activated CD4-positive type I NK T cell [Term] id: CL:0000928 @@ -8558,6 +8783,7 @@ synonym: "activated CD4-negative, CD8-negative type I NK T-lymphocyte" EXACT [] synonym: "activated CD4-negative, CD8-negative type I NKT cell" EXACT [] is_a: CL:0000912 ! helper T cell is_a: CL:0000924 ! CD4-negative, CD8-negative type I NK T cell +relationship: RO:0002202 CL:0000924 ! develops from CD4-negative, CD8-negative type I NK T cell [Term] id: CL:0000929 @@ -8571,6 +8797,7 @@ synonym: "CD4-negative, CD8-negative type I NK T-lymphocyte secreting interferon synonym: "CD4-negative, CD8-negative type I NKT cell secreting interferon-gamma" EXACT [] is_a: CL:0000912 ! helper T cell is_a: CL:0000924 ! CD4-negative, CD8-negative type I NK T cell +relationship: RO:0002202 CL:0000928 ! develops from activated CD4-negative, CD8-negative type I NK T cell [Term] id: CL:0000930 @@ -8584,6 +8811,7 @@ synonym: "CD4-negative, CD8-negative type I NK T-lymphocyte secreting interleuki synonym: "CD4-negative, CD8-negative type I NKT cell secreting interleukin-4" EXACT [] is_a: CL:0000912 ! helper T cell is_a: CL:0000924 ! CD4-negative, CD8-negative type I NK T cell +relationship: RO:0002202 CL:0000928 ! develops from activated CD4-negative, CD8-negative type I NK T cell [Term] id: CL:0000931 @@ -8609,6 +8837,7 @@ synonym: "type II NK T-lymphocyte secreting interferon-gamma" EXACT [] synonym: "type II NKT cell secreting interferon-gamma" EXACT [] is_a: CL:0000912 ! helper T cell is_a: CL:0000922 ! type II NK T cell +relationship: RO:0002202 CL:0000931 ! develops from activated type II NK T cell [Term] id: CL:0000933 @@ -8622,6 +8851,7 @@ synonym: "type II NK T-lymphocyte secreting interleukin-4" EXACT [] synonym: "type II NKT cell secreting interleukin-4" EXACT [] is_a: CL:0000912 ! helper T cell is_a: CL:0000922 ! type II NK T cell +relationship: RO:0002202 CL:0000931 ! develops from activated type II NK T cell [Term] id: CL:0000934 @@ -8633,6 +8863,7 @@ synonym: "CD4-positive, alpha-beta cytotoxic T-cell" EXACT [] synonym: "CD4-positive, alpha-beta cytotoxic T-lymphocyte" EXACT [] is_a: CL:0000624 ! CD4-positive, alpha-beta T cell is_a: CL:0000910 ! cytotoxic T cell +relationship: RO:0002202 CL:0000896 ! develops from activated CD4-positive, alpha-beta T cell [Term] id: CL:0000935 @@ -8656,6 +8887,7 @@ synonym: "LMPP" EXACT [] synonym: "lymphoid-primed multipotent progenitor" EXACT [] is_a: CL:0000837 ! hematopoietic multipotent progenitor cell is_a: CL:0011115 ! precursor cell +relationship: RO:0002202 CL:0002035 ! develops from Slamf1-negative multipotent progenitor cell [Term] id: CL:0000937 @@ -8665,6 +8897,8 @@ def: "Cell committed to natural killer cell lineage that has the phenotype CD122 comment: These cells are also reportedly CD7-low, CD10-negative, CD45RA-positive, alpha-4-beta-7 integrin-high. synonym: "pre-NK cell" EXACT [] is_a: CL:0000623 ! natural killer cell +disjoint_from: CL:0002338 ! CD56-positive, CD161-positive immature natural killer cell +disjoint_from: CL:0002344 ! CD56-negative, CD161-positive immature natural killer cell [Term] id: CL:0000938 @@ -8677,6 +8911,7 @@ synonym: "CD16-negative, CD56-bright NK cell" EXACT [] synonym: "CD56-bright cytokine secreting natural killer cell" EXACT [] synonym: "CD56-bright cytokine secreting NK cell" EXACT [] is_a: CL:0000824 ! mature natural killer cell +disjoint_from: CL:0000939 ! CD16-positive, CD56-dim natural killer cell [Term] id: CL:0000939 @@ -8712,6 +8947,7 @@ namespace: cell def: "A dendritic cell arising in thymus that has the phenotype CD11c-positive, CD11b-negative, and CD45RA-negative." [GO_REF:0000031, GOC:add, GOC:pam, PMID:19273629] comment: In the mouse this cell expresses CD8-alpha-alpha. is_a: CL:0000990 ! conventional dendritic cell +relationship: RO:0002202 CL:0000894 ! develops from DN1 thymic pro-T cell [Term] id: CL:0000942 @@ -8719,6 +8955,7 @@ name: thymic plasmacytoid dendritic cell namespace: cell def: "A plasmacytoid dendritic cell developing in the thymus with phenotype CD11c-negative or low, CD45RA-positive, CD11b-negative, and CD123-positive." [GO_REF:0000031, GOC:add, GOC:pam, GOC:tfm, PMID:19941119] is_a: CL:0000784 ! plasmacytoid dendritic cell +relationship: RO:0002202 CL:0000894 ! develops from DN1 thymic pro-T cell [Term] id: CL:0000943 @@ -8747,6 +8984,7 @@ namespace: cell def: "A lymphocyte of B lineage is a lymphocyte that expresses CD19 on the cell surface. An additional defining characteristic is the commitment to express an immunoglobulin complex." [GO_REF:0000031, GOC:add, GOC:rhs, GOC:tfm, ISBN:0781735149] comment: Types of B lineage lymphocytes include B cells and antibody secreting cells (plasmablasts and plasma cells). Lymphocytes of B cell lineage can be distinguished from those of T cell lineage by their lack of CD3e (as part of the T cell receptor complex). is_a: CL:0000542 ! lymphocyte +relationship: RO:0002202 CL:0000826 ! develops from pro-B cell [Term] id: CL:0000946 @@ -8831,6 +9069,7 @@ synonym: "pre-BII cell" EXACT [] xref: BTO:0001133 xref: CALOHA:TS-0819 is_a: CL:0000817 ! precursor B cell +disjoint_from: CL:0000956 ! pre-B-I cell [Term] id: CL:0000956 @@ -8875,6 +9114,7 @@ synonym: "T2 B-cell" EXACT [] synonym: "T2 B-lymphocyte" EXACT [] synonym: "transitional stage 2 B cell" EXACT [] is_a: CL:0000818 ! transitional stage B cell +relationship: RO:0002202 CL:0000958 ! develops from T1 B cell [Term] id: CL:0000960 @@ -8887,6 +9127,7 @@ synonym: "T3 B-cell" EXACT [] synonym: "T3 B-lymphocyte" EXACT [] synonym: "transitional stage 3 B cell" EXACT [] is_a: CL:0000818 ! transitional stage B cell +relationship: RO:0002202 CL:0000959 ! develops from T2 B cell [Term] id: CL:0000961 @@ -8910,6 +9151,7 @@ synonym: "Bm2 B lymphocyte" EXACT [] synonym: "Bm2 B-cell" EXACT [] synonym: "Bm2 B-lymphocyte" EXACT [] is_a: CL:0000843 ! follicular B cell +relationship: RO:0002202 CL:0000961 ! develops from Bm1 B cell [Term] id: CL:0000963 @@ -8920,6 +9162,7 @@ synonym: "Bm3-delta B lymphocyte" EXACT [] synonym: "Bm3-delta B-cell" EXACT [] synonym: "Bm3-delta B-lymphocyte" EXACT [] is_a: CL:0000844 ! germinal center B cell +relationship: RO:0002202 CL:0000965 ! develops from Bm3 B cell [Term] id: CL:0000964 @@ -8929,13 +9172,11 @@ def: "A germinal center B cell that founds a germinal center, and has the phenot comment: Bm2' B cells are also reportedly CD10-positive, CD39-negative, CD44-negative, CD71-positive, CD77-negative, IgM-positive, IgG-negative, IgA-negative, and IgE-negative. synonym: "Bm2' B lymphocyte" EXACT [] synonym: "Bm2' B-cell" EXACT [] -synonym: "Bm2' B-lymphocyte" EXACT [] synonym: "Bm2-prime B cell" EXACT [] -synonym: "Bm2-prime B lymphocyte " EXACT [] -synonym: "Bm2-prime B-cell " EXACT [] -synonym: "Bm2-prime B-lymphocyte " EXACT [] +synonym: "Bm2-prime B-lymphocyte" EXACT [] synonym: "germinal center founder cell" RELATED [] is_a: CL:0000844 ! germinal center B cell +relationship: RO:0002202 CL:0000962 ! develops from Bm2 B cell [Term] id: CL:0000965 @@ -8948,6 +9189,7 @@ synonym: "Bm3 B-cell" EXACT [] synonym: "Bm3 B-lymphocyte" EXACT [] synonym: "centroblast" RELATED [PMID:8006591] is_a: CL:0000844 ! germinal center B cell +relationship: RO:0002202 CL:0000964 ! develops from Bm2' B cell [Term] id: CL:0000966 @@ -8960,6 +9202,7 @@ synonym: "Bm4 B-cell" EXACT [] synonym: "Bm4 B-lymphocyte" EXACT [] synonym: "centrocyte" RELATED [PMID:17992590] is_a: CL:0000844 ! germinal center B cell +relationship: RO:0002202 CL:0000963 ! develops from Bm3-delta B cell [Term] id: CL:0000967 @@ -8971,6 +9214,7 @@ synonym: "Bm5 B lymphocyte" EXACT [] synonym: "Bm5 B-cell" EXACT [] synonym: "Bm5 B-lymphocyte" EXACT [] is_a: CL:0001053 ! IgD-negative memory B cell +relationship: RO:0002202 CL:0000966 ! develops from Bm4 B cell [Term] id: CL:0000968 @@ -9009,6 +9253,7 @@ synonym: "unswitched memory B lymphocyte" EXACT [] synonym: "unswitched memory B-cell" EXACT [] synonym: "unswitched memory B-lymphocyte" EXACT [] is_a: CL:0000787 ! memory B cell +relationship: RO:0002202 CL:0000980 ! develops from plasmablast [Term] id: CL:0000971 @@ -9035,6 +9280,7 @@ synonym: "class switched memory B lymphocyte" EXACT [] synonym: "class switched memory B-cell" EXACT [] synonym: "class switched memory B-lymphocyte" EXACT [] is_a: CL:0000787 ! memory B cell +relationship: RO:0002202 CL:0000970 ! develops from unswitched memory B cell [Term] id: CL:0000973 @@ -9057,6 +9303,7 @@ name: long lived plasma cell namespace: cell def: "A fully differentiated plasma cell that lives for years, as opposed to months, secretes immunoglobulin, and has the phenotype weakly CD19-positive, CD20-negative, CD38-negative, strongly CD138-positive, MHC Class II-negative, surface immunoglobulin-negative, IgD-negative, and strongly CXCR4-positive. The majority of these cells of this type reside in the bone marrow." [GO_REF:0000031, GOC:msz, GOC:tfm, ISBN:9780781765190, PMID:16014527] is_a: CL:0000786 ! plasma cell +relationship: RO:0002202 CL:0000975 ! develops from short lived plasma cell [Term] id: CL:0000975 @@ -9109,6 +9356,7 @@ comment: This cell type is compatible with the HIPC Lyoplate markers for 'plasma xref: FMA:84371 is_a: CL:0000785 ! mature B cell is_a: CL:0000946 ! antibody secreting cell +relationship: RO:0002202 CL:0000785 ! develops from mature B cell [Term] id: CL:0000981 @@ -9221,6 +9469,7 @@ def: "Immature CD11c-low plasmacytoid dendritic cell is a CD11c-low plasmacytoid comment: Originally described in the dendritic cell ontology (DC_CL:0000006)(PMID:19243617). is_a: CL:0000766 ! myeloid leukocyte is_a: CL:0000989 ! CD11c-low plasmacytoid dendritic cell +relationship: RO:0002202 CL:0001029 ! develops from common dendritic progenitor [Term] id: CL:0000993 @@ -9230,6 +9479,7 @@ def: "Mature CD11c-low plasmacytoid dendritic cell is a CD11c-low plasmacytoid d comment: Originally described in the dendritic cell ontology (DC_CL:0000007)(PMID:19243617). is_a: CL:0000766 ! myeloid leukocyte is_a: CL:0000989 ! CD11c-low plasmacytoid dendritic cell +relationship: RO:0002202 CL:0000992 ! develops from immature CD11c-low plasmacytoid dendritic cell [Term] id: CL:0000994 @@ -9238,6 +9488,7 @@ namespace: cell def: "Immature CD11c-negative plasmacytoid dendritic cell is a CD11c-negative plasmacytoid dendritic cell is CD80-negative, CD86-low and MHCII-low." [GO_REF:0000031, GOC:amm, PMID:15771572, PMID:17850486] comment: Originally described in the dendritic cell ontology (DC_CL:0000008)(PMID:19243617). is_a: CL:0000991 ! CD11c-negative plasmacytoid dendritic cell +relationship: RO:0002202 CL:0000995 ! develops from CD34-positive, CD38-positive common myeloid progenitor OR CD34-positive, CD38-positive common lymphoid progenitor [Term] id: CL:0000995 @@ -9254,6 +9505,7 @@ namespace: cell def: "Mature CD11c-negative plasmacytoid dendritic cell is a CD11c-negative plasmacytoid dendritic cell is CD80-high, CD86-high, MHCII-high and is CD83-positive." [GO_REF:0000031, GOC:amm, PMID:15771572, PMID:17850486] comment: Originally described in the dendritic cell ontology (DC_CL:0000009)(PMID:19243617). is_a: CL:0000991 ! CD11c-negative plasmacytoid dendritic cell +relationship: RO:0002202 CL:0000994 ! develops from immature CD11c-negative plasmacytoid dendritic cell [Term] id: CL:0000997 @@ -9274,6 +9526,7 @@ synonym: "DC.8-4-11b-" EXACT [] synonym: "triple negative dendritic cell" EXACT [] is_a: CL:0000766 ! myeloid leukocyte is_a: CL:0000990 ! conventional dendritic cell +relationship: RO:0002202 CL:0002010 ! develops from pre-conventional dendritic cell [Term] id: CL:0000999 @@ -9284,6 +9537,7 @@ comment: Defined as having a disposition to secreting anti-inflammatory cytokine synonym: "DC.4+" EXACT [] is_a: CL:0000766 ! myeloid leukocyte is_a: CL:0002465 ! CD11b-positive dendritic cell +relationship: RO:0002202 CL:0002010 ! develops from pre-conventional dendritic cell [Term] id: CL:0001000 @@ -9294,6 +9548,7 @@ comment: Cells are defined as having a disposition to secreting inflammatory cyt synonym: "DC.8+" EXACT [] is_a: CL:0000766 ! myeloid leukocyte is_a: CL:0000990 ! conventional dendritic cell +relationship: RO:0002202 CL:0002010 ! develops from pre-conventional dendritic cell [Term] id: CL:0001001 @@ -9312,6 +9567,7 @@ def: "Mature CD8_alpha-negative CD11b-negative dendritic cell is a CD8_alpha-neg comment: These markers are associated with mouse cells. Defined as having a disposition to secretion of anti-inflammatory cytokines. Originally described in the dendritic cell ontology (DC_CL:0000015)(PMID:19243617). is_a: CL:0000841 ! mature conventional dendritic cell is_a: CL:0000998 ! CD8_alpha-negative CD11b-negative dendritic cell +relationship: RO:0002202 CL:0001001 ! develops from immature CD8_alpha-negative CD11b-negative dendritic cell [Term] id: CL:0001003 @@ -9321,6 +9577,7 @@ def: "Mature CD8_alpha-negative CD11b-positive dendritic cell is a CD8_alpha-neg comment: Originally described in the dendritic cell ontology (DC_CL:0000016)(PMID:19243617). is_a: CL:0000841 ! mature conventional dendritic cell is_a: CL:0000999 ! CD4-positive CD11b-positive dendritic cell +relationship: RO:0002202 CL:0000997 ! develops from immature CD8_alpha-negative CD11b-positive dendritic cell [Term] id: CL:0001004 @@ -9339,6 +9596,7 @@ def: "Mature CD8_alpha-positive CD11b-negative dendritic cell is a CD8_alpha-pos comment: Originally described in the dendritic cell ontology (DC_CL:0000018)(PMID:19243617). is_a: CL:0000841 ! mature conventional dendritic cell is_a: CL:0001000 ! CD8_alpha-positive CD11b-negative dendritic cell +relationship: RO:0002202 CL:0001004 ! develops from immature CD8_alpha-positive CD11b-negative dendritic cell [Term] id: CL:0001006 @@ -9366,6 +9624,7 @@ comment: Cell markers are associated with mouse hematopoietic stem cell. Origina synonym: "LSK stem cell" EXACT [] synonym: "Sca1-positive hematopoietic stem cell" EXACT [] is_a: CL:0000037 ! hematopoietic stem cell +disjoint_from: CL:0001024 ! CD34-positive, CD38-negative hematopoietic stem cell [Term] id: CL:0001009 @@ -9384,6 +9643,7 @@ def: "Mature dermal dendritic cell is a dermal dendritic cell that is CD80-high, comment: Originally described in the dendritic cell ontology (DC_CL:0000023)(PMID:19243617). is_a: CL:0000841 ! mature conventional dendritic cell is_a: CL:0001006 ! dermal dendritic cell +relationship: RO:0002202 CL:0001009 ! develops from immature dermal dendritic cell [Term] id: CL:0001011 @@ -9409,6 +9669,7 @@ def: "Mature interstitial dendritic cell is a interstitial dendritic cell that i comment: Originally described in the dendritic cell ontology (DC_CL:0000025)(PMID:19243617). is_a: CL:0000841 ! mature conventional dendritic cell is_a: CL:0001007 ! interstitial dendritic cell +relationship: RO:0002202 CL:0001011 ! develops from immature interstitial dendritic cell [Term] id: CL:0001014 @@ -9444,6 +9705,7 @@ def: "Mature CD1a-positive Langerhans cell is a CD1a-positive Langerhans cell th comment: Originally described in the dendritic cell ontology (DC_CL:0000029)(PMID:19243617). When activated, these cells produce IL-6, IL-8, and IL-15. is_a: CL:0000841 ! mature conventional dendritic cell is_a: CL:0001014 ! CD1a-positive Langerhans cell +relationship: RO:0002202 CL:0001016 ! develops from immature CD1a-positive Langerhans cell [Term] id: CL:0001018 @@ -9469,6 +9731,7 @@ def: "Mature CD8_alpha-low Langerhans cell is a CD8_alpha-low Langerhans cell th comment: These markers are associated with mouse cells. Originally described in the dendritic cell ontology (DC_CL:0000031)(PMID:19243617). is_a: CL:0000841 ! mature conventional dendritic cell is_a: CL:0001015 ! CD8_alpha-low Langerhans cell +relationship: RO:0002202 CL:0001018 ! develops from immature CD8_alpha-low Langerhans cell [Term] id: CL:0001021 @@ -9481,6 +9744,8 @@ synonym: "CD10-positive common lymphocyte progenitor" EXACT [] synonym: "CD10-positive common lymphoid precursor" EXACT [] is_a: CL:0000051 ! common lymphoid progenitor is_a: CL:0000995 ! CD34-positive, CD38-positive common myeloid progenitor OR CD34-positive, CD38-positive common lymphoid progenitor +disjoint_from: CL:0001025 ! Kit-positive, Sca1-positive common lymphoid progenitor +relationship: RO:0002202 CL:0002043 ! develops from CD34-positive, CD38-negative multipotent progenitor cell [Term] id: CL:0001022 @@ -9491,6 +9756,7 @@ comment: These markers are associated with human cells. Originally described in is_a: CL:0000576 ! monocyte is_a: CL:0000839 ! myeloid lineage restricted progenitor cell is_a: CL:0001019 ! CD115-positive monocyte OR common dendritic progenitor +relationship: RO:0002202 CL:0002001 ! develops from CD34-positive, CD38-positive granulocyte monocyte progenitor [Term] id: CL:0001023 @@ -9501,6 +9767,8 @@ comment: Markers are associated with mouse cells. Originally described in the de synonym: "CD117-positive common myeloid precursor" BROAD [] is_a: CL:0001030 ! CD117-positive common myeloid progenitor OR CD217-positive common lymphoid progenitor is_a: CL:0001059 ! common myeloid progenitor, CD34-positive +disjoint_from: CL:0001026 ! CD34-positive, CD38-positive common myeloid progenitor +relationship: RO:0002202 CL:0002035 ! develops from Slamf1-negative multipotent progenitor cell [Term] id: CL:0001024 @@ -9524,6 +9792,7 @@ synonym: "CD217-positive common lymphocyte progenitor" EXACT [] synonym: "CD217-positive common lymphoid precursor" EXACT [] is_a: CL:0000051 ! common lymphoid progenitor is_a: CL:0001030 ! CD117-positive common myeloid progenitor OR CD217-positive common lymphoid progenitor +relationship: RO:0002202 CL:0000936 ! develops from early lymphoid progenitor [Term] id: CL:0001026 @@ -9534,6 +9803,7 @@ comment: Markers are associated with human cell type. Originally described in th synonym: "CD71-positive common myeloid precursor" NARROW [] is_a: CL:0000995 ! CD34-positive, CD38-positive common myeloid progenitor OR CD34-positive, CD38-positive common lymphoid progenitor is_a: CL:0001059 ! common myeloid progenitor, CD34-positive +relationship: RO:0002202 CL:0002043 ! develops from CD34-positive, CD38-negative multipotent progenitor cell [Term] id: CL:0001027 @@ -9544,6 +9814,7 @@ comment: These markers are associated with human cells. Originally described in synonym: "CD7-negative lymphoid precursor" EXACT [] is_a: CL:0000051 ! common lymphoid progenitor is_a: CL:0001012 ! CD7-negative lymphoid progenitor OR granulocyte monocyte progenitor +relationship: RO:0002202 CL:0001021 ! develops from CD34-positive, CD38-positive common lymphoid progenitor [Term] id: CL:0001028 @@ -9553,6 +9824,7 @@ def: "CD7-positive lymphoid progenitor cell is a lymphoid progenitor cell that i comment: These markers are associated with human cells. Originally described in the dendritic cell ontology (DC_CL:0000040)(PMID:19243617). synonym: "CD7-positive lymphoid precursor" EXACT [] is_a: CL:0000051 ! common lymphoid progenitor +relationship: RO:0002202 CL:0001027 ! develops from CD7-negative lymphoid progenitor cell [Term] id: CL:0001029 @@ -9565,6 +9837,7 @@ synonym: "common dendritic precursor" EXACT [] synonym: "pro-DCs" EXACT [PMID:21219184] is_a: CL:0000763 ! myeloid cell is_a: CL:0001019 ! CD115-positive monocyte OR common dendritic progenitor +relationship: RO:0002202 CL:0002009 ! develops from macrophage dendritic cell progenitor [Term] id: CL:0001030 @@ -9645,7 +9918,6 @@ synonym: "CD8+CXCR3+ T cell" EXACT [] synonym: "CD8+CXCR3+ T lymphocyte" EXACT [] synonym: "CD8+CXCR3+ T(reg)" EXACT [] synonym: "CD8+CXCR3+ T-cell" EXACT [] -synonym: "CD8+CXCR3+ T-lymphocyte " EXACT [] synonym: "CD8+CXCR3+ Treg" EXACT [] synonym: "CD8-positive, CXCR3-positive, alpha-beta regulatory T lymphocyte" EXACT [] synonym: "CD8-positive, CXCR3-positive, alpha-beta regulatory T-cell" EXACT [] @@ -9895,6 +10167,7 @@ def: "A CD8-positive, alpha beta memory T cell with the phenotype CD45RA-positiv comment: This cell type is seen human but not found in the mouse. synonym: "TEMRA" EXACT [PMID:16237082] is_a: CL:0000625 ! CD8-positive, alpha-beta T cell +relationship: RO:0002202 CL:0000913 ! develops from effector memory CD8-positive, alpha-beta T cell [Term] id: CL:0001063 @@ -10012,6 +10285,7 @@ def: "An erythroid progenitor cell is Kit-positive, Ly6A-negative, CD41-negative comment: Markers found on mouse cells. synonym: "c- Kit-positive erythroid progenitor cell" EXACT [] is_a: CL:0001066 ! erythroid progenitor cell, mammalian +relationship: RO:0002202 CL:0002006 ! develops from Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell created_by: tmeehan creation_date: 2010-04-26T10:14:16Z @@ -10022,6 +10296,7 @@ namespace: cell def: "A granulocyte monocyte progenitor is CD34-positive, CD38-positive, IL-3receptor-alpha-positive and is CD45RA-negative." [GOC:tfm, PMID:12615892, PMID:19022770] comment: Markers are for human cells. According to different research groups, CD45RA is present or absent on this cell population. is_a: CL:0000557 ! granulocyte monocyte progenitor cell +relationship: RO:0002202 CL:0001026 ! develops from CD34-positive, CD38-positive common myeloid progenitor created_by: tmeehan creation_date: 2010-01-13T03:19:22Z @@ -10032,6 +10307,7 @@ namespace: cell def: "A granulocyte monocyte progenitor that is Kit-positive, CD34-positive, Fc-gamma receptor II/II-positive, and is Sca-1-negative, Il7ra-negative, Cxc3r1-negative, and CD90-negative." [GOC:tfm, http://www.immgen.org/index_content.html, PMID:12615892, PMID:16322423, PMID:19022770, PMID:19273628] comment: Markers are found on mouse cells. is_a: CL:0000557 ! granulocyte monocyte progenitor cell +relationship: RO:0002202 CL:0001023 ! develops from Kit-positive, CD34-positive common myeloid progenitor created_by: tmeehan creation_date: 2010-01-13T03:19:28Z @@ -10043,6 +10319,7 @@ def: "An erythroid progenitor cell that is CD34-positive and is GlyA-negative." comment: Cell markers associated with human cells. xref: FMA:83517 is_a: CL:0001066 ! erythroid progenitor cell, mammalian +relationship: RO:0002202 CL:0002005 ! develops from CD34-positive, CD38-positive megakaryocyte erythroid progenitor cell created_by: tmeehan creation_date: 2010-04-26T10:14:30Z @@ -10053,6 +10330,7 @@ namespace: cell def: "A proerythoblast that is CD34-negative and GlyA-negative." [GOC:ak, GOC:tfm, PMID:19621348] comment: Cell surface markers are associated with human cells. is_a: CL:0000547 ! proerythroblast +relationship: RO:0002202 CL:0002003 ! develops from CD34-positive, GlyA-negative erythroid progenitor cell created_by: tmeehan creation_date: 2010-04-26T10:31:50Z @@ -10083,6 +10361,7 @@ namespace: cell def: "A lineage marker-negative, CD34-positive, IL5r-alpha-positive, and Sca1-negative eosinophil progenitor cell." [GOC:tfm, PMID:17582345] comment: Markers are found on mouse cells. is_a: CL:0000611 ! eosinophil progenitor cell +relationship: RO:0002202 CL:0002002 ! develops from Kit-positive granulocyte monocyte progenitor created_by: tmeehan creation_date: 2010-01-14T03:25:15Z @@ -10093,6 +10372,7 @@ namespace: cell def: "A lineage marker-negative, CD34-positive, CD38-positive, IL3r-alpha-positive, IL5r-alpha-positive, and CD45RA-negative eosinophil progenitor cell." [GOC:tfm, PMCID:PMC2626675] comment: Markers are associated with human cells. is_a: CL:0000611 ! eosinophil progenitor cell +relationship: RO:0002202 CL:0002001 ! develops from CD34-positive, CD38-positive granulocyte monocyte progenitor created_by: tmeehan creation_date: 2010-01-14T03:25:17Z @@ -10105,6 +10385,7 @@ synonym: "MDP" EXACT [] is_a: CL:0000763 ! myeloid cell is_a: CL:0002032 ! hematopoietic oligopotent progenitor cell is_a: CL:0011115 ! precursor cell +relationship: RO:0002202 CL:0000557 ! develops from granulocyte monocyte progenitor cell created_by: tmeehan creation_date: 2010-01-19T02:51:58Z @@ -10115,6 +10396,7 @@ namespace: cell def: "A lin-negative, MHC-II-negative, CD11c-positive, FLT3-positive cell with intermediate expression of SIRP-alpha." [GOC:tfm] is_a: CL:0000763 ! myeloid cell is_a: CL:0002031 ! hematopoietic lineage restricted progenitor cell +relationship: RO:0002202 CL:0001029 ! develops from common dendritic progenitor created_by: tmeehan creation_date: 2010-01-19T03:39:30Z @@ -10126,6 +10408,7 @@ def: "A progenitor cell that can give rise to plasmacytoid and myeloid dendritic comment: Markers are associated with mouse cells. synonym: "murine MDP" EXACT [] is_a: CL:0002009 ! macrophage dendritic cell progenitor +relationship: RO:0002202 CL:0002002 ! develops from Kit-positive granulocyte monocyte progenitor created_by: tmeehan creation_date: 2010-01-26T02:43:40Z @@ -10136,6 +10419,7 @@ namespace: cell def: "A proerythoblast that is Kit-low, Lyg76-positive, and CD71-positive." [GOC:ak, GOC:tfm, PMID:19805084] comment: Markers are associated with mouse cells. is_a: CL:0000547 ! proerythroblast +relationship: RO:0002202 CL:0002000 ! develops from Kit-positive erythroid progenitor cell created_by: tmeehan creation_date: 2010-04-26T10:31:56Z @@ -10146,6 +10430,7 @@ namespace: cell def: "A basophilic erythroblast that is GlyA-positive." [GOC:ak, GOC:tfm, PMID:1638021] comment: Markers are associated with human cells. is_a: CL:0000549 ! basophilic erythroblast +relationship: RO:0002202 CL:0002004 ! develops from CD34-negative, GlyA-negative proerythroblast created_by: tmeehan creation_date: 2010-04-26T10:41:15Z @@ -10156,6 +10441,7 @@ namespace: cell def: "A basophilic erythroblast that is Lyg 76-high and is Kit-negative." [GOC:ak, GOC:tfm, PMID:19805084] comment: Cell surface markers are associated with mouse cells. is_a: CL:0000549 ! basophilic erythroblast +relationship: RO:0002202 CL:0002012 ! develops from Kit-low proerythroblast created_by: tmeehan creation_date: 2010-04-26T10:41:22Z @@ -10166,6 +10452,7 @@ namespace: cell def: "A polychromatophilic erythroblast that is Lyg 76-high and is Kit-negative." [GOC:ak, GOC:tfm, PMID:19805084] synonym: "late basophilic and polychromatophilic erythroblast" BROAD [] is_a: CL:0000550 ! polychromatophilic erythroblast +relationship: RO:0002202 CL:0002014 ! develops from Kit-negative, Ly-76 high basophilic erythroblast created_by: tmeehan creation_date: 2010-04-26T10:53:11Z @@ -10176,6 +10463,7 @@ namespace: cell def: "A polychromatiic erythroblast that is Gly-A-positive and CD71-low." [GOC:ak, GOC:tfm, PMID:1638021] comment: Cell surface markers are associated with human cells. is_a: CL:0000550 ! polychromatophilic erythroblast +relationship: RO:0002202 CL:0002013 ! develops from GlyA-positive basophillic erythroblast created_by: tmeehan creation_date: 2010-04-26T10:53:16Z @@ -10186,6 +10474,7 @@ namespace: cell def: "An orthochromatophilic erythroblast that is ter119-high, CD71-low, and Kit-negative." [GOC:ak, GOC:tfm, PMID:19805084] comment: Cell surface markers associated with mouse cells. is_a: CL:0000552 ! orthochromatic erythroblast +relationship: RO:0002202 CL:0002015 ! develops from Kit-negative, Ly-76 high polychromatophilic erythroblast created_by: tmeehan creation_date: 2010-04-26T11:04:15Z @@ -10196,6 +10485,7 @@ namespace: cell def: "An erythroblast that is GlyA-positive and CD71-negative." [GOC:ak, GOC:tfm, PMID:1638021] comment: Markers associated with human cells. is_a: CL:0000552 ! orthochromatic erythroblast +relationship: RO:0002202 CL:0002016 ! develops from CD71-low, GlyA-positive polychromatic erythroblast created_by: tmeehan creation_date: 2010-04-26T11:04:21Z @@ -10206,6 +10496,7 @@ namespace: cell def: "A reticulocyte that is Ly76-high and is Kit-negative." [GOC:ak, GOC:tfm, PMID:18539294] comment: Marker associated with mouse cells. is_a: CL:0002422 ! enucleated reticulocyte +relationship: RO:0002202 CL:0002017 ! develops from Kit-negative, Ly-76 high orthochromatophilic erythroblasts created_by: tmeehan creation_date: 2010-04-26T11:37:00Z @@ -10216,6 +10507,7 @@ namespace: cell def: "A reticulocyte that is GlyA-positive." [GOC:ak, GOC:tfm, PMID:1638021] comment: Markers is associated with human cells. is_a: CL:0002422 ! enucleated reticulocyte +relationship: RO:0002202 CL:0002018 ! develops from CD71-negative, GlyA-positive orthochromatic erythroblast created_by: tmeehan creation_date: 2010-04-26T11:48:25Z @@ -10226,6 +10518,7 @@ namespace: cell def: "An enucleate erythrocyte that is GlyA-positive." [GOC:ak, GOC:tfm, PMID:20134094] comment: Marker is associated with human cell types. is_a: CL:0000595 ! enucleate erythrocyte +relationship: RO:0002202 CL:0002020 ! develops from GlyA-positive reticulocytes created_by: tmeehan creation_date: 2010-04-26T11:51:22Z @@ -10236,6 +10529,7 @@ namespace: cell def: "An enucleate erythrocyte that is Lyg-76-high." [GOC:ak, GOC:tfm, PMID:19805084] comment: Marker is associated with mouse cell types. is_a: CL:0000595 ! enucleate erythrocyte +relationship: RO:0002202 CL:0002019 ! develops from Ly-76 high reticulocyte created_by: tmeehan creation_date: 2010-04-26T11:51:27Z @@ -10246,6 +10540,7 @@ namespace: cell def: "A megakaroycotye progenitor cell that is CD34-positive, CD41-positive and CD42-positive on the cell surface." [GOC:ak, GOC:tfm, PMID:15232614] comment: Markers are associated with human cell type. is_a: CL:0000553 ! megakaryocyte progenitor cell +relationship: RO:0002202 CL:0002025 ! develops from CD34-positive, CD41-positive, CD42-negative megakaryocyte progenitor cell created_by: tmeehan creation_date: 2010-04-26T02:39:09Z @@ -10256,6 +10551,7 @@ namespace: cell def: "A megakaryocyte progenitor cell that is Kit-positive, CD41-positive, CD9-positive, Sca-1-negative, IL7ralpha-negative, CD150-negative, and Fcgamma receptor II/III-low." [GOC:ak, GOC:tfm, PMID:16951553] comment: Markers are associated with mouse cells. is_a: CL:0000553 ! megakaryocyte progenitor cell +relationship: RO:0002202 CL:0002006 ! develops from Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell created_by: tmeehan creation_date: 2010-04-26T02:39:15Z @@ -10266,6 +10562,7 @@ namespace: cell def: "A megakaryocyte progenitor cell that is CD34-positive, CD41-positive, and CD42-negative." [GOC:ak, GOC:tfm, PMID:15232614] comment: Markers are commonly associated with human cells. is_a: CL:0000553 ! megakaryocyte progenitor cell +relationship: RO:0002202 CL:0002005 ! develops from CD34-positive, CD38-positive megakaryocyte erythroid progenitor cell created_by: tmeehan creation_date: 2010-04-26T03:52:47Z @@ -10276,6 +10573,7 @@ namespace: cell def: "A megakaryocyte progenitor cell that is CD34-negative, CD41-positive and CD42-positive." [GOC:ak, GOC:tfm, PMID:15232614] comment: Markers are commonly associated with human cells. is_a: CL:0000556 ! megakaryocyte +relationship: RO:0002202 CL:0002023 ! develops from CD34-positive, CD41-positive, CD42-positive megakaryocyte progenitor cell created_by: tmeehan creation_date: 2010-04-26T03:59:22Z @@ -10286,6 +10584,7 @@ namespace: cell def: "A megakaryocyte cell with is CD9-positive and CD41-positive." [GOC:tfm] comment: Markers are commonly associated with mouse cells. is_a: CL:0000556 ! megakaryocyte +relationship: RO:0002202 CL:0002024 ! develops from Kit-positive megakaryocyte progenitor cell created_by: tmeehan creation_date: 2010-04-27T10:39:07Z @@ -10298,6 +10597,7 @@ comment: There may be an intermediate cell type. These cells also CD13-positive, synonym: "BMCP" EXACT [] is_a: CL:0000763 ! myeloid cell is_a: CL:0002191 ! granulocytopoietic cell +relationship: RO:0002202 CL:0000557 ! develops from granulocyte monocyte progenitor cell created_by: tmeehan creation_date: 2010-04-27T12:46:33Z @@ -10307,6 +10607,7 @@ name: Fc-epsilon RIalpha-low mast cell progenitor namespace: cell def: "A lineage-negative, Kit-positive, CD45-positive mast cell progenitor that is Fc-epsilon RIalpha-low." [GOC:tfm, PMCID:PMC1312421] is_a: CL:0000831 ! mast cell progenitor +relationship: RO:0002202 CL:0002044 ! develops from Kit-positive, integrin beta7-high basophil mast progenitor cell created_by: tmeehan creation_date: 2010-04-27T01:22:19Z @@ -10317,6 +10618,7 @@ namespace: cell def: "A lineage negative, Sca1-negative basophil progenitor cell that is Fc epsilon RIalpha-high." [GOC:tfm, PMCID:PMC1312421] comment: Markers are associated with mouse cells. is_a: CL:0000613 ! basophil progenitor cell +relationship: RO:0002202 CL:0002044 ! develops from Kit-positive, integrin beta7-high basophil mast progenitor cell created_by: tmeehan creation_date: 2010-04-27T01:22:32Z @@ -10326,6 +10628,8 @@ name: hematopoietic lineage restricted progenitor cell namespace: cell def: "A hematopoietic progenitor cell that is capable of developing into only one lineage of hematopoietic cells." [GOC:tfm, PMID:19022770] is_a: CL:0008001 ! hematopoietic precursor cell +disjoint_from: CL:0002032 ! hematopoietic oligopotent progenitor cell +relationship: RO:0002202 CL:0002032 ! develops from hematopoietic oligopotent progenitor cell created_by: tmeehan creation_date: 2010-01-06T03:43:20Z @@ -10336,6 +10640,7 @@ namespace: cell def: "A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities. Cell lacks hematopoeitic lineage markers." [GOC:tfm, PMID:19022770] comment: This cell type is intended to be compatible with any vertebrate hematopoietic oligopotent progenitor cell. For mammalian hematopoietic oligopotent progenitor cells known to be lineage-negative, please use the term 'hematopoietic oligopotent progenitor cell' (CL_0001060). is_a: CL:0008001 ! hematopoietic precursor cell +relationship: RO:0002202 CL:0000837 ! develops from hematopoietic multipotent progenitor cell created_by: tmeehan creation_date: 2010-01-06T03:43:27Z @@ -10348,6 +10653,7 @@ comment: Markers are associated with mouse cells. These cells are also reportedl synonym: "ST stem cell" EXACT [] synonym: "ST-HSC" EXACT [] is_a: CL:0001008 ! Kit and Sca1-positive hematopoietic stem cell +relationship: RO:0002202 CL:0002034 ! develops from long term hematopoietic stem cell created_by: tmeehan creation_date: 2010-01-08T09:19:25Z @@ -10370,6 +10676,7 @@ namespace: cell def: "A hematopoietic progenitor that has restricted self-renewal capability. Cell is Kit-positive, Ly6-positive, CD150-negative and Flt3-negative." [GOC:tfm, PMID:19022770] comment: Markers are associated with mouse cells. is_a: CL:0000837 ! hematopoietic multipotent progenitor cell +relationship: RO:0002202 CL:0002036 ! develops from Slamf1-positive multipotent progenitor cell created_by: tmeehan creation_date: 2010-01-08T11:16:33Z @@ -10381,6 +10688,8 @@ def: "A hematopoietic progenitor that has some limited self-renewal capability. comment: Markers are associated with mouse cells. synonym: "KSL cell" EXACT [] is_a: CL:0000837 ! hematopoietic multipotent progenitor cell +disjoint_from: CL:0002043 ! CD34-positive, CD38-negative multipotent progenitor cell +relationship: RO:0002202 CL:0002033 ! develops from short term hematopoietic stem cell created_by: tmeehan creation_date: 2010-01-08T11:16:35Z @@ -10428,6 +10737,7 @@ def: "A CD24-low, CD44-negative, NK1.1-negative NK T cell." [GOC:tfm, http://www comment: NKT.44-NK1.1-.Th was assigned as an exact synonym based on sorting strategy displayed at immgene.org. synonym: "NKT.44-NK1.1-.Th" EXACT [] is_a: CL:0000914 ! immature NK T cell +relationship: RO:0002202 CL:0002039 ! develops from immature NK T cell stage I created_by: tmeehan creation_date: 2009-10-29T04:13:43Z @@ -10438,6 +10748,7 @@ namespace: cell def: "A CD24-low, CD44-positive, DX5-low, NK1.1-negative NK T cell." [PMID:17589542] synonym: "NKT.44+.NK1.1-.Th" BROAD [] is_a: CL:0000914 ! immature NK T cell +relationship: RO:0002202 CL:0002040 ! develops from immature NK T cell stage II created_by: tmeehan creation_date: 2009-10-29T04:14:48Z @@ -10448,6 +10759,7 @@ namespace: cell def: "A CD24-low, CD44-positive, DX5-high, NK1.1-negative NK T cell." [GOC:tfm, http://www.immgen.org/index_content.html, PMID:17589542] synonym: "NKT.44+.NK1.1-.Th" BROAD [] is_a: CL:0000914 ! immature NK T cell +relationship: RO:0002202 CL:0002041 ! develops from immature NK T cell stage III created_by: tmeehan creation_date: 2009-10-29T04:17:38Z @@ -10458,6 +10770,7 @@ namespace: cell def: "A hematopoietic multipotent progenitor cell that is CD34-positive, CD38-negative, CD45RA-negative, and CD90-negative." [GOC:tfm, PMID:18371405, PMID:19022770] comment: Cell markers are associated with human hematopoietic multipotent progenitor cells. is_a: CL:0000837 ! hematopoietic multipotent progenitor cell +relationship: RO:0002202 CL:0001024 ! develops from CD34-positive, CD38-negative hematopoietic stem cell created_by: tmeehan creation_date: 2010-01-12T11:14:15Z @@ -10502,6 +10815,7 @@ comment: Markers are commonly associated with mouse cells. These cells are also synonym: "Fr. B" EXACT [] synonym: "Fraction B" EXACT [] is_a: CL:0002400 ! Fraction B/C precursor B cell +relationship: RO:0002202 CL:0002045 ! develops from Fraction A pre-pro B cell created_by: tmeehan creation_date: 2010-04-28T11:56:21Z @@ -10512,6 +10826,7 @@ namespace: cell def: "A pre-B cell precursor is CD19-low, CD22-positive , CD34-positive, CD38-positive." [GOC:dsd, GOC:tfm, PMID:18432934] comment: Late pro-B cells are also reportedly CD10-positive, CD20-negative, CD21-negative, and TdT-positive. Transcription factors: PU.1-positive, Ikaros-positive, E2A-positive, and PAX5-positive. is_a: CL:0000817 ! precursor B cell +relationship: RO:0002202 CL:0002046 ! develops from early pro-B cell created_by: tmeehan creation_date: 2010-04-28T12:06:06Z @@ -10522,6 +10837,7 @@ namespace: cell def: "A precursor B cell is CD45R-positive, CD43-positive, CD24-positive, and BP-positive. Intracellularly expression of surrogate light chain, Rag1 and Rag2, TdT, occurs while there is no expression of mu heavy chain." [GOC:tfm, PMID:17582343] synonym: "Fraction C" RELATED [] is_a: CL:0002400 ! Fraction B/C precursor B cell +relationship: RO:0002202 CL:0002047 ! develops from Fraction B precursor B cell created_by: tmeehan creation_date: 2010-04-28T02:04:01Z @@ -10533,6 +10849,7 @@ def: "A pre-BCR-positive precursor B cell that is CD24-high, CD25-positive, CD43 synonym: "Fr. C'" EXACT [] synonym: "Fraction C-prime" EXACT [] is_a: CL:0000817 ! precursor B cell +relationship: RO:0002202 CL:0002049 ! develops from Fraction C precursor B cell created_by: tmeehan creation_date: 2010-04-28T02:13:46Z @@ -10544,6 +10861,7 @@ def: "A pre-BCR positive T cell that is CD38-high." [GOC:tfm, PMID:18432934] comment: Markers are associated with human cells. synonym: "large pre-B cell type I" RELATED [] is_a: CL:0000952 ! preBCR-positive large pre-B-II cell +relationship: RO:0002202 CL:0002048 ! develops from late pro-B cell created_by: tmeehan creation_date: 2010-04-28T02:27:47Z @@ -10556,6 +10874,7 @@ comment: Fraction D precursor B cells are also reportedly CD24-positive and sIgD synonym: "Fr. D" EXACT [] synonym: "Fraction D pre-B cell" EXACT [GOC:tfm] is_a: CL:0002400 ! Fraction B/C precursor B cell +relationship: RO:0002202 CL:0002050 ! develops from Fraction C' precursor B cell created_by: tmeehan creation_date: 2010-04-28T02:55:16Z @@ -10567,6 +10886,7 @@ def: "A small pre-B cell that is CD22-positive and CD38-low." [GOC:tfm, PMID:184 comment: Markers are associated with human cell. RAG expression maybe diminishing. synonym: "small pre-B cell" EXACT [] is_a: CL:0000954 ! small pre-B-II cell +relationship: RO:0002202 CL:0002051 ! develops from CD38-high pre-BCR positive cell created_by: tmeehan creation_date: 2010-04-28T03:04:48Z @@ -10577,6 +10897,7 @@ namespace: cell def: "An immature B cell that is IgM-positive, CD45R-positive, CD43-low, CD25-negative, and CD127-negative. This cell type has also been described as being AA4-positive, IgM-positive, CD19-positive, CD43-low/negative, and HSA-positive." [GOC:ak, GOC:dsd, GOC:tfm, PMID:17582343, PMID:18432934] comment: Markers associated with mouse cells. These cells are also reportedly sIgD-negative. is_a: CL:0000816 ! immature B cell +relationship: RO:0002202 CL:0002052 ! develops from Fraction D precursor B cell created_by: tmeehan creation_date: 2010-04-28T03:13:47Z @@ -10587,6 +10908,7 @@ namespace: cell def: "An immature B cell that is CD38-negative, CD10-low, CD21-low, and CD22-high." [GOC:tfm, PMID:18432934] comment: Markers are associated with human cell type. is_a: CL:0000816 ! immature B cell +relationship: RO:0002202 CL:0002053 ! develops from CD22-positive, CD38-low small pre-B cell created_by: tmeehan creation_date: 2010-04-28T03:19:14Z @@ -10596,6 +10918,7 @@ name: Fraction F mature B cell namespace: cell def: "A mature B cell subset originally defined as having being CD45R-positive, IgM-positive, IgD-positive and CD43-negative. Subsequent research demonstrated being CD21-positive and CD23-negative and CD93 negative." [GOC:tfm, PMID:17582343] is_a: CL:0000822 ! B-2 B cell +relationship: RO:0002202 CL:0002054 ! develops from Fraction E immature B cell created_by: tmeehan creation_date: 2010-04-30T03:01:48Z @@ -10620,6 +10943,7 @@ def: "A resident monocyte that is Gr-1 low, CD43-positive, and CX3CR1-positive." comment: Markers are associated with mice. The Gr epitope is used to describe this cell type is found on both Ly6c and Ly6g. However, its the Ly6c that is considered the specific marker, and thus used in the cross-product. Also, this cell-type is sometimes described as being Gr1-negative. is_a: CL:0000875 ! non-classical monocyte is_a: CL:0002398 ! Gr1-positive, CD43-positive monocyte +relationship: RO:0002202 CL:0002398 ! develops from Gr1-positive, CD43-positive monocyte created_by: tmeehan creation_date: 2010-06-05T08:25:44Z @@ -10727,7 +11051,7 @@ def: "A neuroendocrine cell found in the epithelium of the lungs and respiratory synonym: "bronchiolar Kulchitsky cell" EXACT [] synonym: "Kultschitzky cell of bronchiole" EXACT [] synonym: "P cell" BROAD [] -synonym: "respiratory enterochromaffin cell " EXACT [] +synonym: "respiratory enterochromaffin cell" EXACT [] xref: FMA:14118 is_a: CL:0000165 ! neuroendocrine cell created_by: tmeehan @@ -10855,6 +11179,7 @@ def: "An epithelial cell derived from endoderm." [FMA:69075, GOC:tfm] xref: FMA:69075 is_a: CL:0000066 ! epithelial cell is_a: CL:0002371 ! somatic cell +relationship: RO:0002202 CL:0000223 ! develops from endodermal cell created_by: tmeehan creation_date: 2010-06-29T03:38:14Z @@ -10866,6 +11191,7 @@ def: "An epithelial cell derived from ectoderm." [FMA:69074, GOC:tfm] xref: FMA:69074 is_a: CL:0000066 ! epithelial cell is_a: CL:0002371 ! somatic cell +relationship: RO:0002202 CL:0000221 ! develops from ectodermal cell created_by: tmeehan creation_date: 2010-06-29T03:38:22Z @@ -10878,6 +11204,7 @@ synonym: "epithelial mesenchymal cell" EXACT [] xref: FMA:69076 is_a: CL:0000066 ! epithelial cell is_a: CL:0002371 ! somatic cell +relationship: RO:0002202 CL:0000222 ! develops from mesodermal cell created_by: tmeehan creation_date: 2010-06-29T03:49:14Z @@ -11403,6 +11730,7 @@ synonym: "gammadelta27-positive" EXACT [] synonym: "gd27-positive" EXACT [] is_a: CL:0000800 ! mature gamma-delta T cell is_a: CL:0000912 ! helper T cell +relationship: RO:0002202 CL:0002126 ! develops from CD25-positive, CD27-positive immature gamma-delta T cell created_by: tmeehan creation_date: 2010-08-18T09:57:19Z @@ -11414,6 +11742,7 @@ def: "A circulating gamma-delta T cell that expresses RORgamma(t), is CD27-negat synonym: "gammadelta-17 cells" EXACT [PMID:21976777] is_a: CL:0000800 ! mature gamma-delta T cell is_a: CL:0000912 ! helper T cell +relationship: RO:0002202 CL:0002126 ! develops from CD25-positive, CD27-positive immature gamma-delta T cell created_by: tmeehan creation_date: 2010-08-18T09:57:29Z @@ -11562,6 +11891,7 @@ synonym: "lymphatic endothelial cell" EXACT [] xref: BTO:0004167 xref: FMA:68458 is_a: CL:0002139 ! endothelial cell of vascular tree +relationship: RO:0002202 CL:0005022 ! develops from vascular lymphangioblast created_by: tmeehan creation_date: 2010-08-24T02:05:28Z @@ -11648,6 +11978,7 @@ def: "A ciliated columnar cell found in the trachea and bronchus. Vary from low xref: FMA:70542 is_a: CL:0002202 ! epithelial cell of tracheobronchial tree is_a: CL:0005012 ! multi-ciliated epithelial cell +relationship: RO:0002202 CL:0002209 ! develops from intermediate epitheliocyte created_by: tmeehan creation_date: 2010-08-24T03:38:29Z @@ -11708,6 +12039,7 @@ synonym: "epithelioid histocyte" EXACT [MESH:A11.329.372.300, PMID:12673090] synonym: "epitheloid macrophage" EXACT [] xref: FMA:83514 is_a: CL:0000235 ! macrophage +relationship: RO:0002202 CL:0000861 ! develops from elicited macrophage created_by: tmeehan creation_date: 2010-08-24T03:48:30Z @@ -11741,6 +12073,7 @@ xref: BTO:0001943 xref: FMA:68650 is_a: CL:0000225 ! anucleate cell is_a: CL:0000311 ! keratin accumulating cell +relationship: RO:0002202 CL:0000312 ! develops from keratinocyte created_by: tmeehan creation_date: 2010-08-24T10:53:03Z @@ -11860,7 +12193,7 @@ id: CL:0002166 name: epithelial cell of Malassez namespace: cell def: "An epithelial cell that remains from the disintegration of the epithelial root sheath involved in the development of teeth." [GOC:tfm, ISBN:0517223651, ISBN:0815129521] -synonym: "epithelial cell rests of Malassez " EXACT [] +synonym: "epithelial cell rests of Malassez" EXACT [] synonym: "epithelial debris of Malassez" EXACT [] xref: FMA:62987 is_a: CL:0002159 ! general ecto-epithelial cell @@ -11993,6 +12326,7 @@ synonym: "folliculostellate cell of pars anterior of adenohypophysis" EXACT [] xref: FMA:83102 is_a: CL:0000642 ! folliculostellate cell is_a: CL:0000710 ! neurecto-epithelial cell +is_a: CL:0002319 ! neural cell is_a: CL:2000004 ! pituitary gland cell created_by: tmeehan creation_date: 2010-08-25T03:10:10Z @@ -12141,6 +12475,7 @@ def: "A eosinophil precursor in the granulocytic series, being a cell intermedia xref: FMA:83541 is_a: CL:0000763 ! myeloid cell is_a: CL:0002191 ! granulocytopoietic cell +relationship: RO:0002202 CL:0002193 ! develops from myelocyte created_by: tmeehan creation_date: 2010-08-30T01:08:15Z @@ -12153,6 +12488,7 @@ xref: BTO:0000734 xref: FMA:83525 is_a: CL:0000763 ! myeloid cell is_a: CL:0002191 ! granulocytopoietic cell +relationship: RO:0002202 CL:0000836 ! develops from promyelocyte created_by: tmeehan creation_date: 2010-08-30T01:08:19Z @@ -12530,6 +12866,7 @@ namespace: cell def: "A lens fiber cell that develops from primary lens fiber; located towards the center of lens; cell organelles are normally degraded or in the process of being degraded." [GOC:tfm, ISBN:0517223651] synonym: "secondary lens fibre" EXACT [] is_a: CL:0011004 ! lens fiber cell +relationship: RO:0002202 CL:0002228 ! develops from primary lens fiber created_by: tmeehan creation_date: 2010-09-07T10:53:39Z @@ -12541,6 +12878,7 @@ def: "A secondary lens fiber cell that lacks a nucleus." [GOC:tfm] synonym: "non-nucleated secondary lens fibre" EXACT [] xref: FMA:67561 is_a: CL:0002225 ! secondary lens fiber +relationship: RO:0002202 CL:0002227 ! develops from nucleated secondary lens fiber created_by: tmeehan creation_date: 2010-09-07T11:15:23Z @@ -12563,6 +12901,7 @@ def: "An elongating cell that rapidly obliterates the lumen of the lens vesicle. synonym: "primary lens fibre" EXACT [] xref: FMA:70613 is_a: CL:0011004 ! lens fiber cell +relationship: RO:0002202 CL:0002223 ! develops from anterior lens cell created_by: tmeehan creation_date: 2010-09-07T11:19:01Z @@ -12735,6 +13074,7 @@ synonym: "smooth muscle fiber of sphincter of pupil" EXACT [] synonym: "smooth muscle fibre of sphincter of pupil" RELATED [] xref: FMA:70611 is_a: CL:0000358 ! sphincter associated smooth muscle cell +relationship: RO:0002202 CL:0000133 ! develops from neurectodermal cell created_by: tmeehan creation_date: 2010-09-08T08:53:42Z @@ -13624,6 +13964,7 @@ namespace: cell def: "A mesothelial cell capable of circulating in the blood by first losing its squamous character. This cell can incorporate into the regenerating mesothelium." [GOC:tfm, PMID:14592528] xref: FMA:86712 is_a: CL:0000081 ! blood cell +relationship: RO:0002202 CL:0000077 ! develops from mesothelial cell created_by: tmeehan creation_date: 2010-09-15T10:47:11Z @@ -13784,6 +14125,7 @@ name: neural crest derived fat cell namespace: cell def: "A fat cell derived from a neural crest cell." [GOC:tfm, PMID:17507398] is_a: CL:0000136 ! fat cell +relationship: RO:0002202 CL:0000005 ! develops from fibroblast neural crest derived created_by: tmeehan creation_date: 2010-09-20T02:25:25Z @@ -13834,6 +14176,7 @@ def: "A natural killer cell that is developmentally immature, has the phenotype comment: Human markers; killer cell immunoglobulin-like receptor 2DL1 is used as a representative example (PRO at this time lacks a KIR superfamily). synonym: "p-NK" RELATED [PMID:12457618] is_a: CL:0000823 ! immature natural killer cell +relationship: RO:0002202 CL:0002344 ! develops from CD56-negative, CD161-positive immature natural killer cell created_by: tmeehan creation_date: 2010-09-21T10:06:53Z @@ -13905,6 +14248,7 @@ def: "An immature natural killer cell that is NK1.1-positive, DX5-positive, Ly49 comment: Markers are associated with mouse cells. synonym: "preNK.BM" BROAD [] is_a: CL:0000823 ! immature natural killer cell +relationship: RO:0002202 CL:0002346 ! develops from Dx5-negative, NK1.1-positive immature natural killer cell created_by: tmeehan creation_date: 2010-09-20T04:41:01Z @@ -13923,6 +14267,7 @@ name: CD27-high, CD11b-high natural killer cell namespace: cell def: "A mature natural killer cell that is CD27-high and CD11b-high. This cell type is capable of interferon-gamma secretion." [GOC:tfm, PMID:19949422] is_a: CL:0002426 ! CD11b-positive, CD27-positive natural killer cell +relationship: RO:0002202 CL:0002349 ! develops from CD27-high, CD11b-low natural killer cell created_by: tmeehan creation_date: 2010-09-21T10:19:49Z @@ -13932,6 +14277,7 @@ name: CD27-low, CD11b-high natural killer cell namespace: cell def: "A CD27-low, CD11b-high natural killer cell that has a higher threshold of activation due to higher expression of inhibitory receptors." [GOC:tfm, PMID:1994922] is_a: CL:0002426 ! CD11b-positive, CD27-positive natural killer cell +relationship: RO:0002202 CL:0002347 ! develops from CD27-high, CD11b-high natural killer cell created_by: tmeehan creation_date: 2010-09-21T10:19:54Z @@ -13941,6 +14287,7 @@ name: CD27-high, CD11b-low natural killer cell namespace: cell def: "A natural killer cell that is CD27-high and CD11b-low." [GOC:tfm, PMID:1994922] is_a: CL:0002426 ! CD11b-positive, CD27-positive natural killer cell +relationship: RO:0002202 CL:0002345 ! develops from CD27-low, CD11b-low immature natural killer cell created_by: tmeehan creation_date: 2010-09-21T10:20:00Z @@ -14006,6 +14353,7 @@ synonym: "primitive erythroblast" EXACT [] synonym: "primitive erythrocyte" EXACT [] synonym: "primitive erythroid cell" EXACT [] is_a: CL:0002417 ! primitive erythroid lineage cell +relationship: RO:0002202 CL:0002361 ! develops from primitive erythroid progenitor created_by: tmeehan creation_date: 2010-09-22T09:27:05Z @@ -14016,6 +14364,7 @@ namespace: cell def: "A primitive erythrocyte that has undergone enucleation. This cell type is 3-6 fold bigger than the fetal derived erythrocytes that they co-circulate with during fetal development. Expresses epsilon-gamma hemoglobin chains." [doi:10.1097/MOH.0b013e3282f97ae1, GOC:tfm, PMID:11495698] synonym: "megalocyte" EXACT [] is_a: CL:0002417 ! primitive erythroid lineage cell +relationship: RO:0002202 CL:0002355 ! develops from primitive red blood cell created_by: tmeehan creation_date: 2010-09-22T09:35:16Z @@ -14026,6 +14375,7 @@ namespace: cell def: "A fetal liver derived enucleated erythrocyte. This erythrocyte resembles adult erythrocytes in that they are small (3- to 6- times smaller than primitive erythrocytes) and produce adult hemaglobins." [GOC:tfm, PMID:11495698] synonym: "macrocyte" EXACT [] is_a: CL:0000595 ! enucleate erythrocyte +relationship: RO:0002202 CL:0002353 ! develops from fetal liver hematopoietic progenitor cell created_by: tmeehan creation_date: 2010-09-22T09:38:32Z @@ -14035,6 +14385,7 @@ name: pyrenocyte namespace: cell def: "Derived from the Greek word pyren (the pit of a stone fruit), this is a transient nucleated cell type that results from exclusion of the nucleus from the primitive erythrocyte." [GOC:tfm] is_a: CL:0002417 ! primitive erythroid lineage cell +relationship: RO:0002202 CL:0002355 ! develops from primitive red blood cell created_by: tmeehan creation_date: 2010-09-22T10:02:37Z @@ -14064,6 +14415,7 @@ def: "A progenitor cell that is capable of forming colonies of primitive erythro synonym: "EryP-CFC" EXACT [] synonym: "inner blood island hemangioblast" EXACT [] is_a: CL:0002417 ! primitive erythroid lineage cell +relationship: RO:0002202 CL:0002418 ! develops from hemangioblast created_by: tmeehan creation_date: 2010-09-22T10:47:28Z @@ -14214,6 +14566,7 @@ namespace: cell def: "A giioblast cell that develops from a migratory neural crest cell. The SCP is embedded among neurons (axons) with minimal extracellular spaces separating them from nerve cell membranes and has no basal lamina. In rodents SCPs are the only cells in the Schwann cell linage that expresses Cdh19." [GOC:tfm] synonym: "Schwann cell precursor cell" EXACT [] is_a: CL:0000030 ! glioblast +relationship: RO:0002202 CL:0000333 ! develops from migratory neural crest cell created_by: tmeehan creation_date: 2010-09-24T02:06:10Z @@ -14224,6 +14577,7 @@ namespace: cell def: "A glial cell that ensheaths multiple small diameter axons in the peripheral nervous system. The non-myelinating Schwann cell is embedded among neurons (axons) with minimal extracellular spaces separating them from nerve cell membranes and has a basal lamina. Cells can survive without an axon present. These cells can de-differentiate into immature Schwann cells." [GOC:cvs, GOC:tfm, ISBN:0721662544] synonym: "Schwann cell" BROAD [] is_a: CL:0002573 ! Schwann cell +relationship: RO:0002202 CL:0002377 ! develops from immature Schwann cell created_by: tmeehan creation_date: 2010-09-24T02:10:26Z @@ -14235,6 +14589,7 @@ def: "A glial cell that develops from a Schwann cell precursor. The immature Sch synonym: "Schwann cell" BROAD [] xref: ZFA:0001725 is_a: CL:0002573 ! Schwann cell +relationship: RO:0002202 CL:0002375 ! develops from Schwann cell precursor created_by: tmeehan creation_date: 2010-09-24T02:10:31Z @@ -14385,6 +14740,7 @@ name: intermediate monocyte namespace: cell def: "A monocyte that has characteristics of both patrolling and inflammatory monocytes." [GOC:tfm, PMID:20628149, PMID:20870168] is_a: CL:0000576 ! monocyte +relationship: RO:0002202 CL:0000860 ! develops from classical monocyte created_by: tmeehan creation_date: 2010-10-04T10:52:03Z @@ -14419,6 +14775,7 @@ comment: Markers are associated with human monocytes. synonym: "non-classical monocyte, human" EXACT [] is_a: CL:0000875 ! non-classical monocyte is_a: CL:0002397 ! CD14-positive, CD16-positive monocyte +relationship: RO:0002202 CL:0002397 ! develops from CD14-positive, CD16-positive monocyte created_by: tmeehan creation_date: 2010-10-04T12:25:42Z @@ -14440,6 +14797,7 @@ namespace: cell def: "An intermediate monocyte that is Gr1-positive, CD43-positive." [GOC:tfm, PMID:20628149] is_a: CL:0001022 ! CD115-positive monocyte is_a: CL:0002393 ! intermediate monocyte +relationship: RO:0002202 CL:0002395 ! develops from Gr1-high classical monocyte created_by: tmeehan creation_date: 2010-10-04T12:49:49Z @@ -14471,6 +14829,7 @@ comment: NOTE: currently variable immune gene segments are not represented in th synonym: "mature DEC precursor" EXACT [] synonym: "mature DETC precursor" EXACT [] is_a: CL:0002404 ! fetal thymocyte +relationship: RO:0002202 CL:0002218 ! develops from immature dendritic epithelial T cell precursor created_by: tmeehan creation_date: 2010-10-07T02:05:46Z @@ -14492,6 +14851,7 @@ def: "A thymocyte that has a T cell receptor consisting of a gamma chain contain comment: NOTE: currently variable immune gene segments are not represented in the OBO Foundry. Cross-product definitions were not made as a result. Also, there are three different nomenclatures for the variable gamma segments. synonym: "fetal Vgamma2-positive" EXACT [] is_a: CL:0002404 ! fetal thymocyte +relationship: RO:0002202 CL:0002378 ! develops from immature Vgamma2-positive fetal thymocyte created_by: tmeehan creation_date: 2010-10-07T02:24:36Z @@ -14535,6 +14895,7 @@ def: "A thymocyte that has a T cell receptor consisting of a gamma chain contain comment: NOTE: currently variable immune gene segments are not represented in the OBO Foundry. Cross-product definitions were not made as a result. Also, there are three different nomenclatures for the variable gamma segments. synonym: "Vgamma2-positive" EXACT [] is_a: CL:0002405 ! gamma-delta thymocyte +relationship: RO:0002202 CL:0002406 ! develops from immature Vgamma2-positive thymocyte created_by: tmeehan creation_date: 2010-10-07T02:53:48Z @@ -14557,6 +14918,7 @@ def: "A thymocyte that has a T cell receptor consisting of a gamma chain contain comment: NOTE: currently variable immune gene segments are not represented in the OBO Foundry. Cross-product definitions were not made as a result. Also, there are three different nomenclatures for the variable gamma segments. synonym: "Vgamma2-negative" EXACT [] is_a: CL:0002405 ! gamma-delta thymocyte +relationship: RO:0002202 CL:0002408 ! develops from immature Vgamma2-negative thymocyte created_by: tmeehan creation_date: 2010-10-07T02:59:08Z @@ -14646,6 +15008,7 @@ name: hemangioblast namespace: cell def: "A pluripotent cell in the yolk sac that can give rise to mesenchymal cells including erythrocytes and endothelial cells." [GOC:tfm, ISBN:0813817986, PMID:11495698] is_a: CL:0000222 ! mesodermal cell +relationship: RO:0002202 CL:0002354 ! develops from yolk sac hematopoietic stem cell created_by: tmeehan creation_date: 2010-10-12T12:21:16Z @@ -14712,6 +15075,7 @@ namespace: cell def: "A DN2 thymocyte that is Kit-low." [GOC:tfm, PMID:20595614] comment: Observed in mice. is_a: CL:0000806 ! DN2 thymocyte +relationship: RO:0002202 CL:0002423 ! develops from DN2a thymocyte created_by: tmeehan creation_date: 2010-10-21T10:12:08Z @@ -14755,6 +15119,7 @@ def: "A double-positive thymocyte that is large (i.e. has a high forward scatter synonym: "activated double-positive thymocyte" EXACT [] synonym: "T.DPb.Th" EXACT [] is_a: CL:0000809 ! double-positive, alpha-beta thymocyte +relationship: RO:0002202 CL:0002427 ! develops from resting double-positive thymocyte created_by: tmeehan creation_date: 2010-10-21T01:59:11Z @@ -14765,6 +15130,7 @@ namespace: cell def: "A double-positive thymocyte that is CD69-positive and has begun positive selection." [GOC:tfm, http://www.immgen.org/index_content.html] synonym: "T.DP69+.Th" EXACT [] is_a: CL:0000809 ! double-positive, alpha-beta thymocyte +relationship: RO:0002202 CL:0002428 ! develops from double-positive blast created_by: tmeehan creation_date: 2010-10-21T02:11:52Z @@ -14775,6 +15141,7 @@ namespace: cell def: "A double-positive thymocyte that is undergoing positive selection, has high expression of the alpha-beta T cell receptor, is CD69-positive, and is in the process of down regulating the CD4 co-receptor." [GOC:tfm, http://www.immgen.org/index_content.html] synonym: "T.4int8+.Th" EXACT [] is_a: CL:0000809 ! double-positive, alpha-beta thymocyte +relationship: RO:0002202 CL:0002429 ! develops from CD69-positive double-positive thymocyte created_by: tmeehan creation_date: 2010-10-21T02:29:19Z @@ -14785,6 +15152,7 @@ namespace: cell def: "A double-positive thymocyte that is undergoing positive selection, has high expression of the alpha-beta T cell receptor, is CD69-positive, and is in the process of down regulating the CD4 co-receptor." [GOC:tfm, http://www.immgen.org/index_content.html] synonym: "T.4int8+.th" EXACT [] is_a: CL:0000809 ! double-positive, alpha-beta thymocyte +relationship: RO:0002202 CL:0002429 ! develops from CD69-positive double-positive thymocyte created_by: tmeehan creation_date: 2010-10-21T02:29:23Z @@ -14797,6 +15165,7 @@ comment: Described in the immgene database as being CD24-intermediate. synonym: "CD24-positive, CD4 single-positive semimature thymocyte" EXACT [] synonym: "T.4SP24int.Th" EXACT [] is_a: CL:0000810 ! CD4-positive, alpha-beta thymocyte +relationship: RO:0002202 CL:0002433 ! develops from CD69-positive, CD4-positive single-positive thymocyte created_by: tmeehan creation_date: 2010-10-21T02:43:52Z @@ -14808,6 +15177,7 @@ def: "A CD4-positive, CD8-negative thymocyte that expresses high levels of the a synonym: "intermediate CD4-single-positive" EXACT [] synonym: "T.4SP69+.Th" EXACT [] is_a: CL:0000810 ! CD4-positive, alpha-beta thymocyte +relationship: RO:0002202 CL:0002431 ! develops from CD4-positive, CD8-intermediate double-positive thymocyte created_by: tmeehan creation_date: 2010-10-21T02:46:02Z @@ -14820,6 +15190,7 @@ comment: Described in the immgene database as being CD24-intermediate. synonym: "CD24-positive, CD8 single-positive semimature thymocyte" EXACT [] synonym: "T.8SP24int.Th" EXACT [] is_a: CL:0000811 ! CD8-positive, alpha-beta thymocyte +relationship: RO:0002202 CL:0002435 ! develops from CD69-positive, CD8-positive single-positive thymocyte created_by: tmeehan creation_date: 2010-10-21T02:59:10Z @@ -14831,6 +15202,7 @@ def: "A CD4-positive, CD8-negative thymocyte that expresses high levels of the a synonym: "intermediate CD8-single-positive" EXACT [] synonym: "T.8SP69+.Th" EXACT [] is_a: CL:0000811 ! CD8-positive, alpha-beta thymocyte +relationship: RO:0002202 CL:0002430 ! develops from CD4-intermediate, CD8-positive double-positive thymocyte created_by: tmeehan creation_date: 2010-10-21T02:59:14Z @@ -14841,6 +15213,7 @@ namespace: cell def: "A mature CD4-positive, CD8-negative alpha-beta T cell found in the thymus that is CD24-low and has high expression of the T cell receptor." [GOC:tfm, http://www.immgen.org/index_content.html] synonym: "T.4SP24-.Th" RELATED [] is_a: CL:0000624 ! CD4-positive, alpha-beta T cell +relationship: RO:0002202 CL:0002432 ! develops from CD24-positive, CD4 single-positive thymocyte created_by: tmeehan creation_date: 2010-10-21T03:31:19Z @@ -14851,6 +15224,7 @@ namespace: cell def: "A mature CD8-positive, CD4-negative alpha-beta T cell found in the thymus that is CD24-low and has high expression of the T cell receptor." [GOC:tfm, http:www.immgen.org/index_content.html] synonym: "T.8SP24-.Th" EXACT [] is_a: CL:0000625 ! CD8-positive, alpha-beta T cell +relationship: RO:0002202 CL:0002434 ! develops from CD24-positive, CD8 single-positive thymocyte created_by: tmeehan creation_date: 2010-10-21T03:51:50Z @@ -15005,6 +15379,7 @@ name: oligodendrocyte precursor cell namespace: cell def: "The cell type from which oligodendrocytes develop. This cell originates from multiple structures within the developing brain including the medial ganglion eminence and the lateral ganglionic eminence. These cells migrate throughout the central nervous system and persist into adulthood where they play an important role in remyelination of injured neurons." [GOC:tfm, PMID:20142420] is_a: CL:0000123 ! neuron associated cell (sensu Vertebrata) +relationship: RO:0002202 CL:0000339 ! develops from glioblast (sensu Vertebrata) created_by: tmeehan creation_date: 2010-11-10T02:51:34Z @@ -15065,9 +15440,6 @@ name: langerin-negative dermal dendritic cell namespace: cell def: "A dermal dendritic cell that is langerin-negative, CD103-negative, and CD11b-positive." [GOC:tfm, http://www.immgen.org/index_content.html] is_a: CL:0001006 ! dermal dendritic cell -relationship: lacks_plasma_membrane_part CL:0002458 ! langerin-positive dermal dendritic cell -relationship: lacks_plasma_membrane_part CL:0002507 ! langerin-positive lymph node dendritic cell -relationship: lacks_plasma_membrane_part CL:0002508 ! langerin-negative, CD103-negative lymph node dendritic cell created_by: tmeehan creation_date: 2010-11-22T04:09:44Z @@ -15088,6 +15460,7 @@ namespace: cell def: "A conventional dendritic cell that is CD103-positive. This cell type is usually found in non-lymphoid tissue." [GOC:tfm, http://www.immgen.org/index_content.html] is_a: CL:0000766 ! myeloid leukocyte is_a: CL:0000990 ! conventional dendritic cell +relationship: RO:0002202 CL:0002010 ! develops from pre-conventional dendritic cell created_by: tmeehan creation_date: 2010-11-23T01:32:43Z @@ -15099,6 +15472,7 @@ def: "A F4/80-negative dendritic cell located in adipose tissue." [GOC:tfm, http is_a: CL:0000766 ! myeloid leukocyte is_a: CL:0000990 ! conventional dendritic cell is_a: CL:0002320 ! connective tissue cell +relationship: RO:0002202 CL:0002010 ! develops from pre-conventional dendritic cell created_by: tmeehan creation_date: 2010-11-23T01:38:21Z @@ -15315,7 +15689,7 @@ id: CL:0002484 name: epithelial melanocyte namespace: cell def: "A melanocyte that produces pigment in the epithelium." [GOC:tfm, MP:0009388] -comment: The text defintion reference to the MP term appears to reference an epidermal melanocyte term. This term represents any melanocyte in any epithelium. +comment: The text defintion reference to the MP term appears to reference an epidermal melanocyte term. This term represents any melanocyte in any epithelium. is_a: CL:0000148 ! melanocyte created_by: tmeehan creation_date: 2010-12-03T03:17:14Z @@ -15326,7 +15700,6 @@ name: retinal melanocyte namespace: cell def: "A melanocyte of the retina. This cell type is distinct from pigmented retinal epithelium." [GOC:tfm, MP:0010190] is_a: CL:0000148 ! melanocyte -is_a: CL:0009004 ! retinal cell created_by: tmeehan creation_date: 2010-12-03T03:25:32Z @@ -15762,6 +16135,7 @@ namespace: cell def: "A mature CD14-positive dermal dendritic cell is CD80-high, CD86-high, MHCII-high and is CD83-positive." [GOC:dsd] is_a: CL:0001010 ! mature dermal dendritic cell is_a: CL:0002526 ! CD14-positive dermal dendritic cell +relationship: RO:0002202 CL:0002527 ! develops from immature CD14-positive dermal dendritic cell [Term] id: CL:0002529 @@ -15787,6 +16161,7 @@ namespace: cell def: "A mature CD1a-positive dermal dendritic cell is CD80-high, CD83-positive, CD86-high, and MHCII-high." [GOC:dsd] is_a: CL:0001010 ! mature dermal dendritic cell is_a: CL:0002529 ! CD1a-positive dermal dendritic cell +relationship: RO:0002202 CL:0002530 ! develops from immature CD1a-positive dermal dendritic cell [Term] id: CL:0002532 @@ -15813,6 +16188,7 @@ namespace: cell def: "A mature CD16-positive myeloid dendritic cell is CD80-high, CD83-positive, CD86-high, and MHCII-high." [GOC:dsd] is_a: CL:0000841 ! mature conventional dendritic cell is_a: CL:0002532 ! CD16-positive myeloid dendritic cell +relationship: RO:0002202 CL:0002533 ! develops from immature CD16-positive myeloid dendritic cell [Term] id: CL:0002535 @@ -17165,6 +17541,7 @@ name: retinal progenitor cell namespace: cell def: "A multi-fate stem cell that can give rise to different retinal cell types including rod and cone cells." [GOC:tfm, PMID:20959166, PMID:21148186] is_a: CL:0000048 ! multi fate stem cell +relationship: RO:0002202 CL:0000133 ! develops from neurectodermal cell created_by: tmeehan creation_date: 2011-08-16T02:38:01Z @@ -17202,6 +17579,7 @@ name: neural crest derived neuroblast namespace: cell def: "A neuroblast derived from a neural crest cell." [GOC:tfm, PMID:17407019] is_a: CL:0000337 ! neuroblast (sensu Vertebrata) +relationship: RO:0002202 CL:0000333 ! develops from migratory neural crest cell created_by: tmeehan creation_date: 2011-08-22T09:24:15Z @@ -17272,6 +17650,7 @@ namespace: cell def: "A non-terminally differentiated cell that originates from the neural crest and differentiates into an iridophore." [CL:CVS] comment: Derived from UBERON:0002342 neural crest. is_a: CL:0000055 ! non-terminally differentiated cell +relationship: RO:0002202 CL:0000333 ! develops from migratory neural crest cell [Term] id: CL:0005002 @@ -17279,6 +17658,7 @@ name: xanthoblast namespace: cell def: "A non-terminally differentiated cell that differentiates into a xanthophore." [CL:CVS] is_a: CL:0000055 ! non-terminally differentiated cell +relationship: RO:0002202 CL:0000333 ! develops from migratory neural crest cell [Term] id: CL:0005003 @@ -17286,6 +17666,7 @@ name: leucoblast namespace: cell def: "A non-terminally differentiated cell that originates from the neural crest and differentiates into a leucophore." [CL:CVS] is_a: CL:0000055 ! non-terminally differentiated cell +relationship: RO:0002202 CL:0000333 ! develops from migratory neural crest cell [Term] id: CL:0005004 @@ -17293,6 +17674,7 @@ name: pigment erythroblast namespace: cell def: "A non-terminally differentiated cell that originates from the neural crest and differentiates into an erythrophore." [CL:CVS] is_a: CL:0000055 ! non-terminally differentiated cell +relationship: RO:0002202 CL:0000333 ! develops from migratory neural crest cell [Term] id: CL:0005005 @@ -17300,6 +17682,7 @@ name: cyanoblast namespace: cell def: "A non-terminally differentiated cell that originates from the neural crest and differentiates into a cyanophore." [CL:CVS] is_a: CL:0000055 ! non-terminally differentiated cell +relationship: RO:0002202 CL:0000333 ! develops from migratory neural crest cell [Term] id: CL:0005006 @@ -17423,7 +17806,7 @@ is_a: CL:0005018 ! ghrelin secreting cell id: CL:0005020 name: lymphangioblast namespace: cell -def: "Lymphatic progenitor cells. " [CL:CVS] +def: "Lymphatic progenitor cells." [CL:CVS] comment: Usually express Prox1, or prox1b. is_a: CL:0000048 ! multi fate stem cell created_by: Ceri @@ -17453,9 +17836,9 @@ creation_date: 2012-01-12T05:21:09Z id: CL:0005023 name: branchiomotor neuron def: "Cranial motor neuron which innervates muscles derived from the branchial (pharyngeal) arches." [ZFIN:CVS] -synonym: "branchi motor neuron " EXACT [] +synonym: "branchi motor neuron" EXACT [] synonym: "special visceral motor neuron" EXACT [] -xref: PMID:14699587 +xref: PMID:14699587 is_a: CL:0015000 ! cranial motor neuron [Term] @@ -17477,7 +17860,7 @@ is_a: CL:0000100 ! motor neuron [Term] id: CL:0005026 name: hepatoblast -def: "Multi fate stem cell that gives rise to to both hepatocytes and cholangiocytes as descendants." [GOC:CVS, PMID:18356246, PMID:20483998 ] +def: "Multi fate stem cell that gives rise to to both hepatocytes and cholangiocytes as descendants." [GOC:CVS, PMID:18356246, PMID:20483998] is_a: CL:0000048 ! multi fate stem cell [Term] @@ -17487,6 +17870,7 @@ namespace: cell def: "Skeletogenic cell that has the potential to develop into an ameloblast. Located in the inner enamel epithelium, these cells elongate, their nuclei shift distally (away from the dental papilla), and their cytoplasm becomes filled with organelles needed for synthesis and secretion of enamel proteins." [GO_REF:0000034, PMCID:PMC2737325] comment: unsure of neural crest contribution. In VSAO we have develops_from CL:0000008 is_a: CL:0000055 ! non-terminally differentiated cell +relationship: RO:0002202 CL:0002077 ! develops from ecto-epithelial cell created_by: haendel creation_date: 2012-06-15T01:27:01Z @@ -17516,6 +17900,7 @@ name: preodontoblast namespace: cell def: "Skeletogenic cell that has the potential to form an odontoblast, deposits predentine, and arises from a cranial neural crest cell." [GO_REF:0000034] is_a: CL:0000055 ! non-terminally differentiated cell +relationship: RO:0002202 CL:0000008 ! develops from migratory cranial neural crest cell created_by: haendel creation_date: 2012-06-15T05:15:11Z @@ -17525,6 +17910,7 @@ name: premigratory neural crest cell namespace: cell def: "Cell that is part of the neural crest region of the neuroepithelium, prior to migration. Note that not all premigratory neural crest cells may become migratory neural crest cells." [UBERONREF:0000002] is_a: CL:0011012 ! neural crest cell +relationship: RO:0002202 CL:0000133 ! develops from neurectodermal cell created_by: haendel creation_date: 2012-06-27T08:27:35Z @@ -17535,6 +17921,7 @@ namespace: cell def: "Cell that is part of the notochord." [GO_REF:0000034] comment: NOTE: TO DO, notochord development still needs work. is_a: CL:0000003 ! native cell +relationship: RO:0002202 CL:0007006 ! develops from chordamesodermal cell created_by: haendel creation_date: 2012-06-27T08:47:31Z @@ -17584,6 +17971,8 @@ namespace: cell def: "Skeletogenic cell that has the potential to transform into an osteoblast, and develops from neural crest or mesodermal cells." [GO_REF:0000034] synonym: "osteoprogenitor cell" EXACT [] is_a: CL:0000055 ! non-terminally differentiated cell +relationship: RO:0002202 CL:0000222 ! develops from mesodermal cell +relationship: RO:0002202 CL:0000333 ! develops from migratory neural crest cell created_by: haendel creation_date: 2012-06-27T10:57:21Z @@ -17594,6 +17983,7 @@ namespace: cell def: "Neuron that is part of the enteric nervous system." [CL:MAH] is_a: CL:0000029 ! neuron neural crest derived is_a: CL:0000107 ! autonomic neuron +relationship: RO:0002202 CL:0002607 ! develops from migratory enteric neural crest cell created_by: haendel creation_date: 2012-06-28T08:20:31Z @@ -17649,7 +18039,7 @@ creation_date: 2012-12-30T12:43:15Z [Term] id: CL:0007017 name: Stiftchenzellen -def: "An epidermal cell with apical microvilli or a single apical projection have synaptic associations with nerve fibres in the epidermis. " [PMID:1087183] +def: "An epidermal cell with apical microvilli or a single apical projection have synaptic associations with nerve fibres in the epidermis." [PMID:1087183] comment: Taxon specificity not yet fully known, but are known in anuran larvae but not in adults. is_a: CL:0000006 ! neuronal receptor cell is_a: CL:0000098 ! sensory epithelial cell @@ -17694,7 +18084,7 @@ created_by: haendel [Term] id: CL:0007022 name: micropylar cell -def: "A specialized pore forming cell of the follicle, located adjacent to the animal pole of the oocyte. The micropylar cell makes the single micropyle (pore) through the chorion through which the sperm fertilizes the egg." [PMID:18582455 , ZFA:0005239] +def: "A specialized pore forming cell of the follicle, located adjacent to the animal pole of the oocyte. The micropylar cell makes the single micropyle (pore) through the chorion through which the sperm fertilizes the egg." [PMID:18582455, ZFA:0005239] synonym: "plug cell" EXACT [] is_a: CL:0000548 ! animal cell created_by: haendel @@ -17702,7 +18092,7 @@ created_by: haendel [Term] id: CL:0007023 name: flask cell -def: "Epidermal cell rich in mitochondria. In amphibians, appears during metamorphosis. " [DOI:10.1007/BF00717048] +def: "Epidermal cell rich in mitochondria. In amphibians, appears during metamorphosis." [DOI:10.1007/BF00717048] is_a: CL:0000003 ! native cell created_by: haendel @@ -17724,6 +18114,7 @@ name: skeletal muscle fiber def: "A transversely striated, synctial cell of skeletal muscle. It is formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." [GOC:tfm, ISBN:0323052908] is_a: CL:0000188 ! cell of skeletal muscle is_a: CL:0002372 ! myotube +relationship: RO:0002202 CL:0000515 ! develops from skeletal muscle myoblast [Term] id: CL:0008003 @@ -17786,6 +18177,7 @@ namespace: cell def: "A skeletal muscle satellite cell that divides by stem cell division. A proportion of this population undergoes symmetric stem cell division, producing two skeletal muscle satellite stem cells. The rest undergo asymmetric stem cell division - retaining their identity while budding off a daughter cell that differentiates into an adult skeletal muscle myoblast." [PMID:23303905] is_a: CL:0000035 ! single fate stem cell is_a: CL:0000594 ! skeletal muscle satellite cell +disjoint_from: CL:0008020 ! skeletal muscle satellite myogenic cell [Term] id: CL:0008012 @@ -17797,7 +18189,7 @@ is_a: CL:0000594 ! skeletal muscle satellite cell [Term] id: CL:0008013 name: cranial visceromotor neuron -def: " A visceromotor motor neuron whose soma is located in the hindbrain, and which synapses to parasympathetic neurons that innervate tear glands, sweat glands, and the smooth muscles of the head." [PMID:14699587] +def: "A visceromotor motor neuron whose soma is located in the hindbrain, and which synapses to parasympathetic neurons that innervate tear glands, sweat glands, and the smooth muscles of the head." [PMID:14699587] is_a: CL:0005025 ! visceromotor neuron is_a: CL:0015000 ! cranial motor neuron @@ -17821,6 +18213,7 @@ name: activated skeletal muscle satellite cell namespace: cell def: "A skeletal muscle cell that has become mitotically active - typically following muscle damage." [PMID:21849021, PMID:23303905] is_a: CL:0000594 ! skeletal muscle satellite cell +relationship: RO:0002202 CL:0008012 ! develops from quiescent skeletal muscle satellite cell [Term] id: CL:0008017 @@ -17894,6 +18287,47 @@ namespace: cell def: "An epithelial cell that is part of the epithelium of a tracheal tube in an open tracheal system, such as that found in insects." [GOC:dos] is_a: CL:0000066 ! epithelial cell +[Term] +id: CL:0008027 +name: rod bipolar cell (sensu Mus) +def: "A bipolar neuron found in the retina that is synapsed by rod photoreceptor cells. These neurons have axons that arborize and synapse to targets in inner plexiform layers 4 and 5 and depolarize in response to light." [] +is_a: CL:0000751 ! rod bipolar cell +created_by: dos +creation_date: 2017-06-29T11:05:22Z + +[Term] +id: CL:0008028 +name: visual system neuron +is_a: CL:0000540 ! neuron +created_by: dos +creation_date: 2017-07-09T19:12:36Z + +[Term] +id: CL:0008029 +name: inhibitory neuron +is_a: CL:0000151 ! secretory cell +is_a: CL:0000540 ! neuron +created_by: dos +creation_date: 2017-07-12T11:10:52Z + +[Term] +id: CL:0008030 +name: excitatory neuron +is_a: CL:0000151 ! secretory cell +is_a: CL:0000540 ! neuron +created_by: dos +creation_date: 2017-07-12T11:11:06Z + +[Term] +id: CL:0008031 +name: cortical interneuron +is_a: CL:0000099 ! interneuron + +[Term] +id: CL:0008032 +name: rosehip neuron +is_a: CL:0010011 ! cerebral cortex GABAergic interneuron + [Term] id: CL:0009000 name: sensory neuron of spinal nerve @@ -17908,7 +18342,7 @@ name: compound eye retinal cell def: "Any cell in the compound eye, a light sensing organ composed of ommatidia." [] xref: GOC:pr xref: PMID:12021768 -is_a: CL:0009004 ! retinal cell +is_a: CL:0002371 ! somatic cell [Term] id: CL:0009002 @@ -18024,8 +18458,6 @@ is_a: CL:1001611 ! cerebellar neuron id: CL:0010011 name: cerebral cortex GABAergic interneuron def: "a GABAergic interneuron that is part_of a cerebral cortex" [] -is_a: CL:0000402 ! CNS interneuron -is_a: CL:0002609 ! neuron of cerebral cortex is_a: CL:0011005 ! GABAergic interneuron [Term] @@ -18207,7 +18639,7 @@ is_a: CL:0009004 ! retinal cell [Term] id: CL:0011105 name: dopamanergic interplexiform cell -def: "A type of interneuron in the retinal inner nuclear layer which \ncarries information from the inner plexiform layer and the outer \nplexiform layer, using dopamine. " [GOC:NV, PMID:12771169] +def: "A type of interneuron in the retinal inner nuclear layer which \ncarries information from the inner plexiform layer and the outer \nplexiform layer, using dopamine." [GOC:NV, PMID:12771169] comment: This type of cell is found in Danio rerio. is_a: CL:0000700 ! dopaminergic neuron is_a: CL:0011104 ! interplexiform cell @@ -18215,7 +18647,7 @@ is_a: CL:0011104 ! interplexiform cell [Term] id: CL:0011106 name: GABAnergic interplexiform cell -def: "A type of interneuron in the retinal inner nuclear layer which \ncarries information from the inner plexiform layer and the outer \nplexiform layer using GABA. " [GOC:NV, PMID:12771169] +def: "A type of interneuron in the retinal inner nuclear layer which \ncarries information from the inner plexiform layer and the outer \nplexiform layer using GABA." [GOC:NV, PMID:12771169] comment: This type of cell is found in many mammals. is_a: CL:0011005 ! GABAergic interneuron is_a: CL:0011104 ! interplexiform cell @@ -18223,8 +18655,8 @@ is_a: CL:0011104 ! interplexiform cell [Term] id: CL:0011107 name: Muller cell -def: "Astrocyte-like radial glial cell that extends vertically throughout the retina, with the nucleus are usually in the middle of the inner nuclear layer.\n" [GOC:NV, PMID:21911394] -synonym: "Muller glia " EXACT [] +def: "Astrocyte-like radial glial cell that extends vertically throughout the retina, with the nucleus are usually in the middle of the inner nuclear layer." [GOC:NV, PMID:21911394] +synonym: "Muller glia" EXACT [] synonym: "Müller cell" EXACT [] is_a: CL:0000681 ! radial glial cell is_a: CL:0009004 ! retinal cell @@ -18232,7 +18664,7 @@ is_a: CL:0009004 ! retinal cell [Term] id: CL:0011108 name: colon epithelial cell -def: "Epithelial cell that is part of the colon epithelium. " [GOC:NV] +def: "Epithelial cell that is part of the colon epithelium." [GOC:NV] synonym: "colonic epithelial cell" EXACT [] is_a: CL:0002253 ! epithelial cell of large intestine @@ -18284,7 +18716,7 @@ is_a: CL:1001610 ! bone marrow hematopoietic cell id: CL:0011115 name: precursor cell def: "A cell that, by division or terminal differentiation, can give rise to other cell types." [GOC:dos] -comment: Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell. +comment: Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell. is_a: CL:0000003 ! native cell [Term] @@ -18314,9 +18746,9 @@ is_a: CL:0000681 ! radial glial cell [Term] id: CL:0015000 name: cranial motor neuron -def: "Motor neuron that innervate muscles that control eye, jaw, and facial movements of the vertebrate head and parasympathetic neurons that innervate certain glands and organs. " [ZFIN:CVS\n] +def: "Motor neuron that innervate muscles that control eye, jaw, and facial movements of the vertebrate head and parasympathetic neurons that innervate certain glands and organs." [ZFIN:CVS\n] synonym: "cranial motoneuron" EXACT [] -xref: PMID:14699587 \n +xref: PMID:14699587 is_a: CL:0000100 ! motor neuron [Term] @@ -19151,15 +19583,6 @@ def: "A M cell that is part of the epithelium proper of ileum." [GOC:tfm] xref: FMA:263138 is_a: CL:1000353 ! microfold cell of epithelium of small intestine -[Term] -id: CL:1000359 -name: microfold cell of epithelium proper of appendix -namespace: cell -def: "A M cell that is part of the epithelium proper of appendix." [GOC:tfm] -xref: FMA:263140 -is_a: CL:1000360 ! microfold cell of epithelium proper of large intestine -is_a: CL:1000405 ! epithelial cell of appendix - [Term] id: CL:1000360 name: microfold cell of epithelium proper of large intestine @@ -20007,6 +20430,7 @@ def: "An epithelial cell that is part of the bile duct. Cholangiocytes contribut synonym: "epithelial cell of bile duct" EXACT [] xref: FMA:86481 is_a: CL:0000069 ! branched duct epithelial cell +relationship: RO:0002202 CL:0005026 ! develops from hepatoblast [Term] id: CL:1000489 @@ -20103,7 +20527,6 @@ name: kidney pelvis cell namespace: cell xref: KUPO:0001018 is_a: CL:1000497 ! kidney cell -is_a: CL:1000601 ! ureteral cell [Term] id: CL:1000507 @@ -20318,17 +20741,17 @@ id: CL:1000702 name: kidney pelvis smooth muscle cell namespace: cell xref: KUPO:0001113 +is_a: CL:0000192 ! smooth muscle cell is_a: CL:1000505 ! kidney pelvis cell -is_a: CL:1000979 ! ureter smooth muscle cell [Term] id: CL:1000703 name: kidney pelvis urothelial cell namespace: cell xref: KUPO:0001114 +is_a: CL:0000731 ! urothelial cell is_a: CL:0002518 ! kidney epithelial cell is_a: CL:1000505 ! kidney pelvis cell -is_a: CL:1000706 ! ureter urothelial cell [Term] id: CL:1000706 @@ -21231,7 +21654,7 @@ is_a: CL:1001588 ! colon glandular cell [Term] id: CL:1001586 name: mammary gland glandular cell -def: "Glandular cell of mammary epithelium. Example: glandular cells of large and intermediate ducts, glandular cells in terminal ducts." [NPX:PDR;HPA\:HPA] +def: "Glandular cell of mammary epithelium. Example: glandular cells of large and intermediate ducts, glandular cells in terminal ducts." [HPA:HPA, NPX:PDR] synonym: "breast glandular cell" RELATED [CALOHA:TS-1272] synonym: "breast glandular cells" RELATED [CALOHA:TS-1272] synonym: "mammary glandular cell" RELATED [CALOHA:TS-1272] @@ -21281,7 +21704,7 @@ is_a: CL:0000150 ! glandular epithelial cell [Term] id: CL:1001591 name: oviduct glandular cell -def: "Glandular cell of oviduct epithelium. Example: peg cells, ciliated cells." [NPX:PDR;HPA\:HPA] +def: "Glandular cell of oviduct epithelium. Example: peg cells, ciliated cells." [HPA:HPA, NPX:PDR] synonym: "fallopian tube glandular cell" RELATED [CALOHA:TS-1277] synonym: "fallopian tube glandular cells" RELATED [CALOHA:TS-1277] synonym: "uterine tube glandular cell" RELATED [CALOHA:TS-1277] @@ -21302,7 +21725,7 @@ is_a: CL:1000415 ! epithelial cell of gall bladder [Term] id: CL:1001593 name: parathyroid glandular cell -def: "Glandular cell of parathyroid epithelium. Example: Parathyroid chief cell and parathyroid oxyphil cells." [NPX:PDR;HPA\:HPA] +def: "Glandular cell of parathyroid epithelium. Example: Parathyroid chief cell and parathyroid oxyphil cells." [HPA:HPA, NPX:PDR] synonym: "parathyroid gland glandular cell" RELATED [CALOHA:TS-1279] synonym: "parathyroid gland glandular cells" RELATED [CALOHA:TS-1279] xref: CALOHA:TS-1279 @@ -21320,7 +21743,7 @@ is_a: CL:0002658 ! glandular cell of the large intestine [Term] id: CL:1001596 name: salivary gland glandular cell -def: "Glandular cell of salivary gland. Example: Serous cells, mucous cells, cuboidal epithelial cells of the intercalated ducts, simple cuboidal epithelium of the striated ducts, epithelial cells of excretory ducts." [NPX:PDR;HPA\:HPA] +def: "Glandular cell of salivary gland. Example: Serous cells, mucous cells, cuboidal epithelial cells of the intercalated ducts, simple cuboidal epithelium of the striated ducts, epithelial cells of excretory ducts." [HPA:HPA, NPX:PDR] synonym: "salivary gland glandular cells" RELATED [CALOHA:TS-1282] xref: CALOHA:TS-1282 is_a: CL:0000150 ! glandular epithelial cell @@ -21339,7 +21762,7 @@ is_a: CL:0000150 ! glandular epithelial cell [Term] id: CL:1001598 name: small intestine glandular cell -def: "A glandular cell found in the epithelium of the small intestine. Example: Enterocytes, Goblet cells, enteroendocrine cells; Paneth cells; M cells; Somatostatin-secreting Cells (D-cells) ." [NCI_Thesaurus:Small_Intestinal_Glandular_Cell;NPX\:PDR] +def: "A glandular cell found in the epithelium of the small intestine. Example: Enterocytes, Goblet cells, enteroendocrine cells; Paneth cells; M cells; Somatostatin-secreting Cells (D-cells) ." [NCI_Thesaurus:Small_Intestinal_Glandular_Cell, NPX:PDR] synonym: "small bowel glandular cell" RELATED [CALOHA:TS-1286] synonym: "small intestinal glandular cell" RELATED [CALOHA:TS-1286] synonym: "small intestine glandular cells" RELATED [CALOHA:TS-1286] @@ -21351,7 +21774,7 @@ is_a: CL:0002254 ! epithelial cell of small intestine [Term] id: CL:1001599 name: pancreas exocrine glandular cell -def: "Glandular cell of exocrine pancreas epithelium. Example: pancreatic acinar cell, glandular cells in pancreatic canaliculi, glandular cells in pancreatic ducts." [NPX:PDR;HPA\:HPA] +def: "Glandular cell of exocrine pancreas epithelium. Example: pancreatic acinar cell, glandular cells in pancreatic canaliculi, glandular cells in pancreatic ducts." [HPA:HPA, NPX:PDR] synonym: "exocrine pancreas glandular cell" RELATED [CALOHA:TS-1242] synonym: "pancreas exocrine glandular cells" RELATED [CALOHA:TS-1242] xref: BTO:0000028 @@ -21383,7 +21806,7 @@ is_a: CL:0002319 ! neural cell [Term] id: CL:1001603 name: lung macrophage -def: "Circulating macrophages and tissue macrophages (alveolar macrophages) of lung." [NPX:PDR;HPA\:HPA] +def: "Circulating macrophages and tissue macrophages (alveolar macrophages) of lung." [HPA:HPA, NPX:PDR] synonym: "lung macrophages" RELATED [CALOHA:TS-0576] xref: CALOHA:TS-0576 is_a: CL:0000235 ! macrophage @@ -21471,7 +21894,7 @@ id: CL:2000004 name: pituitary gland cell namespace: cell def: "Any cell that is part of a pituitary gland." [GOC:TermGenie] -is_a: CL:0002319 ! neural cell +is_a: CL:0000003 ! native cell created_by: TermGenie creation_date: 2014-03-26T22:14:56Z @@ -21709,7 +22132,7 @@ id: CL:2000030 name: hypothalamus native cell namespace: cell def: "Any native cell that is part of a hypothalamus." [GOC:TermGenie] -is_a: CL:0002319 ! neural cell +is_a: CL:0000003 ! native cell created_by: TermGenie creation_date: 2014-06-25T01:17:50Z @@ -22361,46 +22784,61 @@ created_by: TermGenie creation_date: 2015-12-03T16:42:40Z [Typedef] -id: has_completed -name: has_completed - -[Typedef] -id: has_high_plasma_membrane_amount -name: has_high_plasma_membrane_amount -def: "A relation between a cell and molecule or complex such that every instance of the cell has a high number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617)." [PMID:19243617] - -[Typedef] -id: has_low_plasma_membrane_amount -name: has_low_plasma_membrane_amount -def: "A relation between a cell and molecule or complex such that every instance of the cell has a low number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617)." [PMID:19243617] - -[Typedef] -id: has_not_completed -name: has_not_completed - -[Typedef] -id: has_relational_adjective -name: has_relational_adjective -namespace: uberon -comment: Used to connect a class to an adjectival form of its label. For example, a class with label 'intestine' may have a relational adjective 'intestinal'. -xref: UBPROP:0000007 -is_metadata_tag: true +id: BFO:0000050 +name: part of +def: "a core relation that holds between a part and its whole" [] +property_value: IAO:0000111 "is part of" xsd:string +property_value: IAO:0000112 "my brain is part of my body (continuant parthood, two material entities)" xsd:string +property_value: IAO:0000112 "my stomach cavity is part of my stomach (continuant parthood, immaterial entity is part of material entity)" xsd:string +property_value: IAO:0000112 "this day is part of this year (occurrent parthood)" xsd:string +property_value: IAO:0000116 "Everything is part of itself. Any part of any part of a thing is itself part of that thing. Two distinct things cannot be part of each other." xsd:string +property_value: IAO:0000116 "Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See https://code.google.com/p/obo-relations/wiki/ROAndTime" xsd:string +property_value: IAO:0000116 "Parthood requires the part and the whole to have compatible classes: only an occurrent can be part of an occurrent; only a process can be part of a process; only a continuant can be part of a continuant; only an independent continuant can be part of an independent continuant; only an immaterial entity can be part of an immaterial entity; only a specifically dependent continuant can be part of a specifically dependent continuant; only a generically dependent continuant can be part of a generically dependent continuant. (This list is not exhaustive.)\n\nA continuant cannot be part of an occurrent: use 'participates in'. An occurrent cannot be part of a continuant: use 'has participant'. A material entity cannot be part of an immaterial entity: use 'has location'. A specifically dependent continuant cannot be part of an independent continuant: use 'inheres in'. An independent continuant cannot be part of a specifically dependent continuant: use 'bearer of'." xsd:string +property_value: IAO:0000118 "part_of" xsd:string +property_value: RO:0001900 RO:0001901 +property_value: RO:0040042 BFO:0000002 +property_value: RO:0040042 BFO:0000003 +property_value: RO:0040042 BFO:0000004 +property_value: RO:0040042 BFO:0000017 +property_value: RO:0040042 BFO:0000019 +property_value: RO:0040042 BFO:0000020 +property_value: RO:0040042 BFO:0000031 +property_value: seeAlso http://ontologydesignpatterns.org/wiki/Community:Parts_and_Collections +property_value: seeAlso http://ontologydesignpatterns.org/wiki/Submissions:PartOf +property_value: seeAlso http://www.obofoundry.org/ro/#OBO_REL:part_of xsd:string +is_transitive: true +is_a: RO:0002131 ! overlaps [Typedef] -id: immediate_transformation_of -name: immediate_transformation_of -synonym: "direct_transformation_of" EXACT [https://orcid.org/0000-0002-6601-2165] -synonym: "immediately transforms from" EXACT [SIO:000658] -xref: http://semanticscience.org/resource/SIO_000658 -property_value: IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl +id: RO:0002131 +name: overlaps +def: "x overlaps y if and only if there exists some z such that x has part z and z part of y" [] +subset: ro-eco +property_value: IAO:0000114 IAO:0000125 +property_value: RO:0001900 RO:0001901 +holds_over_chain: BFO:0000050 BFO:0000050 +expand_expression_to: "http://purl.obolibrary.org/obo/BFO_0000051 some (http://purl.obolibrary.org/obo/BFO_0000050 some ?Y)" [] [Typedef] -id: lacks_part -name: lacks_part -expand_expression_to: "http://purl.obolibrary.org/obo/BFO_0000051 exactly 0 ?Y" [] +id: RO:0002202 +name: develops from +def: "x develops from y if and only if either (a) x directly develops from y or (b) there exists some z such that x directly develops from z and z develops from y" [] +comment: This is the transitive form of the develops from relation +property_value: IAO:0000114 IAO:0000125 +property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string +property_value: IAO:0000117 "Melissa Haendel" xsd:string +property_value: IAO:0000117 "Terry Meehan" xsd:string +is_transitive: true +is_a: RO:0002258 ! developmentally preceded by [Typedef] -id: lacks_plasma_membrane_part -name: lacks_plasma_membrane_part -expand_expression_to: "http://purl.obolibrary.org/obo/BFO_0000051 exactly 0 (http://purl.obolibrary.org/obo/GO_0005886 and http://purl.obolibrary.org/obo/BFO_0000051 some ?Y)" [] +id: RO:0002258 +name: developmentally preceded by +def: "Candidate definition: x developmentally related to y if and only if there exists some developmental process (GO:0032502) p such that x and y both participates in p, and x is the output of p and y is the input of p" [] +comment: This relation groups together various other developmental relations. It is fairly generic, encompassing induction, developmental contribution and direct and transitive develops from +property_value: IAO:0000114 IAO:0000125 +property_value: IAO:0000116 "false" xsd:boolean +property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000232 "In general you should not use this relation to make assertions - use one of the more specific relations below this one" xsd:string diff --git a/src/ontology/cl-basic.owl b/src/ontology/cl-basic.owl index eeb6c87ee..a9c2f7503 100644 --- a/src/ontology/cl-basic.owl +++ b/src/ontology/cl-basic.owl @@ -1,438 +1,17 @@ + xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"> - Chris Mungall - - Ceri van Slyke - Melissa Haendel - Terry Meehan - Yvonne Bradford - - David Osumi-Sutherland - Nicole Vasilevsky - Jim Balhoff - Alexander Diehl + - - - - - - - - - definition - - - - - - - - imported from - - - - - - - - expand expression to - - - - - - - - expand assertion to - - - - - - - - term replaced by - - - - - - - - UBPROP:0000007 - uberon - true - has_relational_adjective - Used to connect a class to an adjectival form of its label. For example, a class with label 'intestine' may have a relational adjective 'intestinal'. - has_relational_adjective - - - - - - - - preferred term when talking about an instance of this class in Homo sapiens - - - - - - - - - latin term - - - - - - - - - plural term - - - - - - - - - abstract upper-level terms not directly useful for analysis - - - - - - - - - - - - - - - - - - - - - - - - - - - subset_property - - - - - - - - synonym_type_property - - - - - - - - consider - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - has_alternative_id - - - - - - - - has_broad_synonym - - - - - - - - database_cross_reference - - - - - - - - has_exact_synonym - - - - - - - - has_narrow_synonym - - - - - - - - has_obo_namespace - - - - - - - - has_related_synonym - - - - - - - - has_synonym_type - - - - - - - - - - - - - - in_subset - - - - - - - - - - - - - - - - - - - - - - - - - - shorthand - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - has_completed - - - - - - - - A relation between a cell and molecule or complex such that every instance of the cell has a high number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617). - has_high_plasma_membrane_amount - - - - - A relation between a cell and molecule or complex such that every instance of the cell has a high number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617). - PMID:19243617 - - - - - - - - A relation between a cell and molecule or complex such that every instance of the cell has a low number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617). - has_low_plasma_membrane_amount - - - - - A relation between a cell and molecule or complex such that every instance of the cell has a low number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617). - PMID:19243617 - - - - - - - - has_not_completed - - - - - - - - http://purl.obolibrary.org/obo/BFO_0000051 exactly 0 ?Y - lacks_part - - - - - - - - http://purl.obolibrary.org/obo/BFO_0000051 exactly 0 (http://purl.obolibrary.org/obo/GO_0005886 and http://purl.obolibrary.org/obo/BFO_0000051 some ?Y) - lacks_plasma_membrane_part - - - - - - - - - http://semanticscience.org/resource/SIO_000658 - direct_transformation_of - immediately transforms from - immediate_transformation_of - immediate_transformation_of - - - - - direct_transformation_of - https://orcid.org/0000-0002-6601-2165 - - - - - immediately transforms from - SIO:000658 - - - - - - A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane. - CALOHA:TS-2035 - FMA:68646 - GO:0005623 - KUPO:0000002 - VHOG:0001533 - WBbt:0004017 - XAO:0003012 - cell - - The definition of cell is intended to represent all cells, and thus a cell is defined as a material entity and not an anatomical structure, which implies that it is part of an organism (or the entirety of one). - cell - - - - - A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane. - CARO:mah - + @@ -473,44 +33,13 @@ - A cultured cell that is freshly isolated from a organismal source, or derives in culture from such a cell prior to the culture being passaged. - BTO:0002290 - primary cell culture cell - unpassaged cultured cell - cell - primary cell line cell - Covers cells actively being cultured or stored in a quiescent state for future use. - primary cultured cell - - - - A cultured cell that is freshly isolated from a organismal source, or derives in culture from such a cell prior to the culture being passaged. - ReO:mhb - - - OBSOLETE: A cell line cell that is expected to be capable of an unlimited number of divisions, and is thus able to support indefinite growth/propagation in vitro as part of a immortal cell line. - - continuous cell line cell - permanent cell line cell - cell - Obsoleted in July 2013 and replaced by the CLO 'immortal cell line cell' class, as a result of CLO-OBI-CL alignment efforts. - -Covers cells actively being cultured or stored in a quiescent state for future use. - obsolete immortal cell line cell - true - - - - - OBSOLETE: A cell line cell that is expected to be capable of an unlimited number of divisions, and is thus able to support indefinite growth/propagation in vitro as part of a immortal cell line. - ReO:mhb - + @@ -518,41 +47,13 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell that is found in a natural setting, which includes multicellular organism cells 'in vivo' (i.e. part of an organism), and unicellular organisms 'in environment' (i.e. part of a natural environment). - CARO:0000013 - cell in vivo - cell - - To accommodate unicellular organisms better, 'cell in vivo' has been re-labeled 'native cell' to better represent its intended meaning - that is, that it is a cell in the context of a multicellular organism or in a natural environment. 'Native' is intended to contrast with 'in vitro', which refers to cells or other biological entities that have been intentionally placed in a controlled, non-natural setting for the purpose of study or manipulation. (MAH 1.12.12). - native cell - - - - A cell that is found in a natural setting, which includes multicellular organism cells 'in vivo' (i.e. part of an organism), and unicellular organisms 'in environment' (i.e. part of a natural environment). - CARO:mah - - - OBSOLETE: A classification of cells by the organisms within which they are contained. - CL:0000000 - CL:0000003 - CL:0001034 - cell - This term was made obsolete because there is no difference in meaning between it and 'cell', as any cell can be classified by its species. If you have used this term in annotation, please replace it with cell (CL:0000000), native cell (CL:0000003), or cell in vitro (CL:0001034) as appropriate. - obsolete cell by organism - true - - - - - OBSOLETE: A classification of cells by the organisms within which they are contained. - FB:ma - + @@ -560,8 +61,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - fibroblast neural crest derived @@ -571,9 +70,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - neuronal receptor cell (sensu Animalia) - cell - neuronal receptor cell @@ -582,16 +78,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell found in the embryo before the formation of all the gem layers is complete. - cell - early embryonic cell - - - - A cell found in the embryo before the formation of all the gem layers is complete. - GOC:tfm - @@ -599,30 +86,13 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - migratory cranial neural crest cell - - Obsolete. Use PO:0000079 from Plant Ontology instead. An elongated cell with approximately wedge-shaped ends, found in the vascular cambium, which gives rise to the elements of the axial system in the secondary vascular tissues. - CL:0000274 - cell - xylem initial - xylem mother cell - replaced_by: PO:0000079 - obsolete fusiform initial - true - - - - - Obsolete. Use PO:0000079 from Plant Ontology instead. An elongated cell with approximately wedge-shaped ends, found in the vascular cambium, which gives rise to the elements of the axial system in the secondary vascular tissues. - ISBN:0471245208 - + @@ -630,17 +100,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell in vitro that is or has been maintained or propagated as part of a cell culture. - cell - Note that this class was re-labeled to 'cultured cell' instead of 'cell line cell', as it intent was clarified to cover any cultured cells of multicellular and unicellular organisms. This includes cells actively being cultured, or cells that have been cultured but are stored in a quiescent state for future use. In having been cultured, cells must establish homeostasis and often replicate in a foreign environment. Accomodation of this stress initiates a selection of cells fit for such challenges, wherein necessary adaptive biochemical and.or genetic changes can occur. These changes can set them apart from the in vivo cells from which they derive, and such changes will typically accumulate and change over increasing time in culture. - cultured cell - - - - A cell in vitro that is or has been maintained or propagated as part of a cell culture. - ReO:mhb - @@ -648,34 +108,19 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - migratory trunk neural crest cell - - CL:0000000 - CL:0000003 - CL:0001034 - cell - This term was made obsolete because there is no difference in meaning between it and 'cell', as any cell can be classified. If you have used this term in annotation, please replace it with cell (CL:0000000), native cell (CL:0000003), or cell in vitro (CL:0001034) as appropriate. - obsolete cell by class - true - + - - CL:0000140 - cell - obsolete dentine secreting cell - true - + @@ -684,9 +129,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - germline stem cell - cell - germ line stem cell @@ -695,12 +137,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - FMA:72290 - MA:0002765 - VHOG:0001531 - ncithesaurus:Spermatogenic_Cell - cell - male germ cell @@ -710,8 +146,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - male germ line stem cell @@ -720,23 +154,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A male germ cell that develops from spermatogonia. The euploid primary spermatocytes undergo meiosis and give rise to the haploid secondary spermatocytes which in turn give rise to spermatids. - BTO:0001275 - CALOHA:TS-0951 - EMAPA:31484 - FBbt:00004936 - FMA:84049 - WBbt:0006799 - cell - spermatocyte - - - - - A male germ cell that develops from spermatogonia. The euploid primary spermatocytes undergo meiosis and give rise to the haploid secondary spermatocytes which in turn give rise to spermatids. - GOC:tfm - MESH:A05.360.490.890.880 - + @@ -745,23 +163,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A male germ cell that develops from the haploid secondary spermatocytes. Without further division, spermatids undergo structural changes and give rise to spermatozoa. - BTO:0001274 - CALOHA:TS-0950 - EMAPA:31486 - FBbt:00004942 - FMA:72294 - WBbt:0006800 - nematoblast - cell - spermatid - - - - - A male germ cell that develops from the haploid secondary spermatocytes. Without further division, spermatids undergo structural changes and give rise to spermatozoa. - MESH:A05.360.490.890.860 - + @@ -771,26 +173,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A mature male germ cell that develops from a spermatid. - BTO:0001277 - BTO:0002046 - CALOHA:TS-0949 - FBbt:00004954 - FMA:67338 - WBbt:0006798 - sperm cell - spermatozoid - spermatozoon - cell - sperm - - - - - A mature male germ cell that develops from a spermatid. - GOC:tfm - MESH:A05.360.490.890 - + @@ -798,21 +181,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An euploid male germ cell of an early stage of spermatogenesis. - BTO:0000958 - CALOHA:TS-2193 - EMAPA:31482 - FBbt:00004935 - FMA:72291 - cell - spermatogonium - - - - An euploid male germ cell of an early stage of spermatogenesis. - MESH:A05.360.490.890.900 - @@ -820,21 +189,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Female germ cell is a germ cell that supports female gamete production. - MA:0000388 - VHOG:0001530 - ncithesaurus:Egg - cell - female germ cell - - - - Female germ cell is a germ cell that supports female gamete production. - GOC:tfm - PMID:11023867 - PMID:20454446 - @@ -843,8 +198,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - female germ line stem cell @@ -853,23 +206,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A female germ cell that has entered meiosis. - BTO:0000964 - CALOHA:TS-0711 - FBbt:00004886 - FMA:18644 - WBbt:0006797 - cell - oogonium - oocyte - - - - - A female germ cell that has entered meiosis. - GOC:tfm - ISBN:0721662544 - + @@ -877,18 +214,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An undifferentiated germ cell that proliferates rapidly and gives rise to oocytes. - FMA:83673 - cell - oogonial cell - - - - An undifferentiated germ cell that proliferates rapidly and gives rise to oocytes. - GOC:tfm - ISBN:0721662544 - @@ -896,25 +222,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A female gamete where meiosis has progressed to metaphase II and is able to participate in fertilization. - BTO:0000369 - BTO:0003801 - CALOHA:TS-2191 - FBbt:00057012 - FMA:67343 - MA:0000388 - mature oocyte - ovum - cell - egg cell - - - - - A female gamete where meiosis has progressed to metaphase II and is able to participate in fertilization. - GOC:tfm - ISBN:0721662544 - + @@ -923,20 +231,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A germline cell that contributes to the development of the oocyte by transferring cytoplasm directly to oocyte. - BTO:0000953 - FBbt:00004878 - cell - nurse cell - invertebrate nurse cell - - - - A germline cell that contributes to the development of the oocyte by transferring cytoplasm directly to oocyte. - GOC:tfm - PMID:15848391 - @@ -944,8 +239,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - smooth muscle cell neural crest derived @@ -954,8 +247,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - CNS neuron (sensu Nematoda and Protostomia) @@ -964,8 +255,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - neuron neural crest derived @@ -974,9 +263,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - FBbt:00005145 - cell - glioblast @@ -986,20 +272,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell that will develop into a neuron often after a migration phase. - BTO:0000930 - FBbt:00005146 - FMA:70563 - cell - neuroblast - - - - A cell that will develop into a neuron often after a migration phase. - GOC:NV - http://en.wikipedia.org/wiki/Neuroblast - @@ -1007,18 +280,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell of a platelike structure, especially a thickened plate of ectoderm in the early embryo, from which a sense organ develops. - neural placode cell - cell - neuroplacodal cell - - - - A cell of a platelike structure, especially a thickened plate of ectoderm in the early embryo, from which a sense organ develops. - GOC:tfm - ISBN:0618947256 - @@ -1026,17 +288,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An apocrine cell is a secretory cell characterized loss of part of the cytoplasm during the process of secretion - secretions are budded off through the plasma membrane producing membrane bound vesicles containing the secreted substance. - cell - apocrine cell - - - - An apocrine cell is a secretory cell characterized loss of part of the cytoplasm during the process of secretion - secretions are budded off through the plasma membrane producing membrane bound vesicles containing the secreted substance. - GOC:tfm - ISBN:0721662544 - @@ -1044,19 +296,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. - CALOHA:TS-2086 - FMA:63368 - cell - stem cell - - - - A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. - GOC:tfm - MESH:A11.872 - @@ -1064,19 +304,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A stem cell that self-renews as well as give rise to a single mature cell type. - FMA:70569 - unipotent stem cell - unipotential stem cell - cell - single fate stem cell - - - - A stem cell that self-renews as well as give rise to a single mature cell type. - GOC:tfm - @@ -1084,8 +312,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - epithelial fate stem cell @@ -1095,30 +321,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. Hematopoietic stem cells lack cell markers of effector cells (lin-negative). Lin-negative is defined by lacking one or more of the following cell surface markers: CD2, CD3 epsilon, CD4, CD5 ,CD8 alpha chain, CD11b, CD14, CD19, CD20, CD56, ly6G, ter119. - BTO:0000725 - CALOHA:TS-0448 - FMA:70337 - FMA:86475 - VHOG:0001485 - HSC - blood forming stem cell - hemopoietic stem cell - cell - colony forming unit hematopoietic - Markers differ between species, and two sets of markers have been described for mice. HSCs are reportedly CD34-positive, CD45-positive, CD48-negative, CD150-positive, CD133-positive, and CD244-negative. - hematopoietic stem cell - - - - - A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. Hematopoietic stem cells lack cell markers of effector cells (lin-negative). Lin-negative is defined by lacking one or more of the following cell surface markers: CD2, CD3 epsilon, CD4, CD5 ,CD8 alpha chain, CD11b, CD14, CD19, CD20, CD56, ly6G, ter119. - GOC:add - GOC:dsd - GOC:tfm - PMID:19022770 - http://en.wikipedia.org/wiki/Hematopoietic_stem_cell - + @@ -1127,24 +330,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A progenitor cell committed to the erythroid lineage. - BTO:0004911 - cell - BFU-E - CFU-E - blast forming unit erythroid - burst forming unit erythroid - colony forming unit erythroid - erythroid stem cell - erythroid progenitor cell - - - - - A progenitor cell committed to the erythroid lineage. - GOC:add - ISBN:0721601464 - + @@ -1152,19 +338,8 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell that is within the developmental lineage of gametes and is able to pass along its genetic material to offspring. - cell - - Originally this term had some plant germ line cell children. - germ line cell + - - - - A cell that is within the developmental lineage of gametes and is able to pass along its genetic material to offspring. - GOC:tfm - ISBN:0721662544 - @@ -1173,26 +348,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A myeloid progenitor cell committed to the monocyte lineage. This cell is CD11b-positive, has basophilic cytoplasm, euchromatin, and the presence of a nucleolus. - CALOHA:TS-1195 - FMA:83553 - cell - CFU-M - colony forming unit macrophage - colony forming unit monocyte - monocyte stem cell - Morphology: mononuclear cell, diameter 12-20 _M, non-granular, N/C ratio 3/1 - 4/1; markers: CD11b (shared with many other myeloid cells); location: Adult: bone marrow; fetal: liver, Yolk Sac; role or process: hematopoiesis, monocyte development; lineage: hematopoietic, myeloid. - monoblast - - - - - A myeloid progenitor cell committed to the monocyte lineage. This cell is CD11b-positive, has basophilic cytoplasm, euchromatin, and the presence of a nucleolus. - GOC:add - PMID:1104740 - http://en.wikipedia.org/wiki/Monoblast - http://www.copewithcytokines.de - + @@ -1201,26 +357,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A fully differentiated eosinophil, a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin. Cells are also differentiated from other granulocytes by a small nuclear-to-cytoplasm ratio (1:3). This cell type is CD49d-positive. - polymorphonuclear leucocyte - polymorphonuclear leukocyte - mature eosinocyte - mature eosinophil leucocyte - mature eosinophil leukocyte - cell - Eosinophils are CD125-positive (IL-5R), GM-CSFR-positive, IL-3R-positive, VLA4-positive. They can also express MHC Class I & II, CD4, CD9, CD11a, CD11b, CD11c, CD13, CD15, CD16, CD17, CD18, CD24, CD25,CD28, CD29, CD32, CD33, CD35, CD37, CD39, CD43, CD44, CD45, CD45RB, CD45RO, CD46, CD47, CD48, CD49d, CD49f, CD50, CD52, CD53, CD54, CD55, CD58, CD59, CD62L, CD63, CD65, CD66, CD69, CD71, CD76, CD80, CD81, CD82, CD86, CD87, CD88, CD89, CD92, CD95, CD97, CD98, CD99, CD100, CD101, CD116, CD117, CD119, CD120, CD123, CD124, CD125, CD131, CD137, CD139, CD148, CD149, CD151, CD153, CD156, CD162, CD161, CD162, CD165, CD174, CD182, CD183, CD191, CD192, CD193, CD196, CD213, IL9R, ad integrin, beta-7 integrin, FceRI, IL13Ra1, TGFbR, PAFR, LTB4R, C3aR, CystLT1R, CystLT2R, fMLPR, CRTH2 (PGD2 receptor), histamine 4R, IDO, KYN, PAR-2, Siglec-8, Siglec-10, LIR1, LIR2, LIR3, LIR7, TLR7, TLR8, and VLA-4. Eosinophils can also secrete CXCL1, eotaxin-1, GM-CSF, IL-2, IL-3, IL-4, IL-5, IL-6, IL-8, IL-10, IL-12, IL-13, IL-16, IL-18, IFN-gamma, LTC4, MIP-1alpha, NGF, PAF, RANTES, substance P, TGF-alpha, TGF-beta, TNF-alpha, and VIP. - mature eosinophil - - - - - A fully differentiated eosinophil, a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin. Cells are also differentiated from other granulocytes by a small nuclear-to-cytoplasm ratio (1:3). This cell type is CD49d-positive. - GOC:add - GOC:dsd - GOC:tfm - ISBN:0721601464 - http://www.cap.org - + @@ -1229,21 +366,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A myeloblast committed to the neutrophil lineage. This cell type is GATA-1 positive, C/EBPa-positive, AML-1-positive, c-myb-positive and has low expression of PU.1 transcription factor. - cell - neutrophilic granuloblast - These cells are CD11b-negative, CD15-negative, CD16-negative, CD35-negative, CD49d-positive, CD68-positive, lactotransferrin-negative, and fMLP receptor-negative. They are found in the Band 3 fraction. - neutrophilic myeloblast - - - - A myeloblast committed to the neutrophil lineage. This cell type is GATA-1 positive, C/EBPa-positive, AML-1-positive, c-myb-positive and has low expression of PU.1 transcription factor. - GOC:add - ISBN:0721601464 - PMID:12560239 - PMID:15514007 - @@ -1253,55 +376,19 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A fully differentiated basophil, a granular leukocyte with an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm that contains coarse granules of variable size. Basophils contain vasoactive amines such as histamine and serotonin, which are released on appropriate stimulation. - CL:0000739 - polymorphonuclear leucocyte - polymorphonuclear leukocyte - BTO:0001026 - CALOHA:TS-0688 - mature basophil leucocyte - mature basophil leukocyte - cell - Mature basophils are also capable of producing IL-3, IL-5, IL-6, IL-8, IL-13, IL-25, CCL22, tslp, vegf, and LTC4. - mature basophil - - - - - A fully differentiated basophil, a granular leukocyte with an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm that contains coarse granules of variable size. Basophils contain vasoactive amines such as histamine and serotonin, which are released on appropriate stimulation. - GOC:add - GOC:dsd - GOC:tfm - ISBN:0721601464 - PMID:18466030 - PMID:19231594 - PMID:20837449 - http://www.cap.org - + - - OBSOLETE (was not defined before being made obsolete). - cell - Consider using term 'pro-T cell ; CL:0000827' or the term 'thymocyte ; CL:0000893' or one of its children instead. - obsolete thymus processed stem cell - true - + - - OBSOLETE (was not defined before being made obsolete). - cell - Consider using term 'pro-B cell ; CL:0000826' or the term 'immature B cell ; CL:0000816 or one of its children instead. - obsolete bursa processed stem cell - true - + @@ -1309,25 +396,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - - Neural stem cell is characterized as an undifferentiated cell that originates from the neuroectoderm and has the capacity both to perpetually self-renew without differentiating and to generate multiple types of lineage-restricted progenitors. - BTO:0002881 - CALOHA:TS-2360 - FMA:86684 - NSC - neural stem cell - cell - neuronal stem cell - - - - - Neural stem cell is characterized as an undifferentiated cell that originates from the neuroectoderm and has the capacity both to perpetually self-renew without differentiating and to generate multiple types of lineage-restricted progenitors. - GOC:tfm - MESH:D058953 - PMID:15247488 - http://en.wikipedia.org/wiki/Neural_stem_cell - + @@ -1336,21 +405,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A stem cell that can give rise to multiple lineages of cells. - FMA:84789 - multi-fate stem cell - multifate stem cell - multipotent cell - multipotent stem cell - cell - multi fate stem cell - - - - A stem cell that can give rise to multiple lineages of cells. - GOC:add - @@ -1358,70 +413,10 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages. - BTO:0004730 - CMP - common myeloid precursor - cell - CFU-GEMM - CFU-S - colony forming unit granulocyte, erythrocyte, macrophage, and megakaryocyte - multipotential myeloid stem cell - myeloid stem cell - pluripotent stem cell (bone marrow) - This cell type is intended to be compatible with any vertebrate common myeloid progenitor. For mammalian CMP known to be CD34-positive, please use the term 'common myeloid progenitor, CD34-positive' (CL_0001059). - common myeloid progenitor - - - - - A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages. - GOC:add - ISBN:0878932437 - MESH:D023461 - - - - - CMP - ISBN:0878932437 - - - - - CFU-GEMM - ISBN:0878932437 - - - - - CFU-S - ISBN:0878932437 - - - - - colony forming unit granulocyte, erythrocyte, macrophage, and megakaryocyte - ISBN:0878932437 - - - - - multipotential myeloid stem cell - ISBN:0878932437 - - - - - myeloid stem cell - ISBN:0878932437 - - - - - pluripotent stem cell (bone marrow) - ISBN:0878932437 - + + + + @@ -1431,29 +426,9 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A progenitor cell committed to the megakaryocyte and erythroid lineages. - CFU-EM - CFU-MegE - MEP - Meg/E progenitor - colony forming unit erythroid megakaryocyte - megakaryocyte/erythrocyte progenitor - megakaryocyte/erythroid progenitor cell - cell - MEPs are reportedly CD19-negative, CD34-negative, CD45RA-negative, CD110-positive, CD117-positive, and SCA1-negative and reportedly express the transcription factors GATA-1 and NF-E2. - megakaryocyte-erythroid progenitor cell - - - - - A progenitor cell committed to the megakaryocyte and erythroid lineages. - GOC:add - GOC:dsd - GOC:tfm - MESH:D055015 - PMID:16647566 - http://en.wikipedia.org/wiki/Megakaryocyte-erythroid_progenitor_cell - + + + @@ -1462,31 +437,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A oligopotent progenitor cell committed to the lymphoid lineage. - CL:0000044 - CLP - common lymphocyte precursor - common lymphocyte progenitor - common lymphoid precursor - cell - ELP - committed lymphopoietic stem cell - early lymphocyte progenitor - lymphoid stem cell - lymphopoietic stem cell - CLP are CD7-positive, CD10-positive, CD19-negative, CD34-positive, CD45RA-positive, CD79a-negative, CD127-positive, AA4.1-positive, RAG-negative, Sca-1-low, sIgM-negative, sIgD-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Expression of transcription factors include E2A-positive, EBF-positive, Ikaros-negative, PU.1-negative, and Pax5-negative. - common lymphoid progenitor - - - - - A oligopotent progenitor cell committed to the lymphoid lineage. - GOC:add - GOC:dsd - GOC:tfm - PMID:10407577 - PMID:16551251 - + @@ -1494,19 +445,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A stem cell from which all cells of the body can form. - FMA:84790 - totipotential stem cell - cell - totipotent stem cell - - - - A stem cell from which all cells of the body can form. - GOC:add - GOC:tfm - @@ -1514,8 +453,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - bone matrix secreting cell @@ -1524,20 +461,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A precursor cell with a limited number of potential fates. - BTO:0000125 - FMA:84782 - blast cell - cell - define using PATO mulit-potent or oligopotent? - non-terminally differentiated cell - - - - A precursor cell with a limited number of potential fates. - SANBI:mhl - @@ -1545,23 +469,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell that is commited to differentiating into a muscle cell. Embryonic myoblasts develop from the mesoderm. They undergo proliferation, migrate to their various sites, and then differentiate into the appropriate form of myocytes. Myoblasts also occur as transient populations of cells in muscles undergoing repair. - BTO:0000222 - CALOHA:TS-0650 - FBbt:00005083 - FMA:70335 - VHOG:0001529 - cell - myoblast - - - - - A cell that is commited to differentiating into a muscle cell. Embryonic myoblasts develop from the mesoderm. They undergo proliferation, migrate to their various sites, and then differentiate into the appropriate form of myocytes. Myoblasts also occur as transient populations of cells in muscles undergoing repair. - GOC:tfm - MESH:A11.635 - PMID:21849021 - + @@ -1569,24 +477,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped. - BTO:0000452 - CALOHA:TS-0362 - FMA:63877 - VHOG:0001482 - cell - These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative. - fibroblast - - - - - A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped. - ISBN:0517223651 - MESH:A11.329.228 - MESH:D005347 - http://en.wikipedia.org/wiki/Fibroblast - + @@ -1595,21 +486,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Skeletogenic cell that is typically non-terminally differentiated, secretes an avascular, GAG rich matrix; is not buried in cartilage tissue matrix, retains the ability to divide, located adjacent to cartilage tissue (including within the perichondrium), and develops from prechondroblast (and thus prechondrogenic) cell. - BTO:0003607 - FMA:66783 - chrondoplast - cell - chondroblast - - - - Skeletogenic cell that is typically non-terminally differentiated, secretes an avascular, GAG rich matrix; is not buried in cartilage tissue matrix, retains the ability to divide, located adjacent to cartilage tissue (including within the perichondrium), and develops from prechondroblast (and thus prechondrogenic) cell. - GOC:tfm - GO_REF:0000034 - ISBN:0618947256 - @@ -1619,25 +496,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Skeletogenic cell that produces enamel, overlies the odontogenic papilla, and arises from the differentiation of a preameloblast cell. - CL:0000053 - CL:0000139 - BTO:0001663 - FMA:70576 - amelocyte - enamel secreting cell - cell - non-encoded relationship from VSAO produces VSAO:0000066 - ameloblast - - - - - Skeletogenic cell that produces enamel, overlies the odontogenic papilla, and arises from the differentiation of a preameloblast cell. - GOC:tfm - GO_REF:0000034 - MESH:A11.436.107 - + @@ -1647,21 +506,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Skeletogenic cell that secretes dentine matrix, is derived from the odontogenic papilla, and develops from a preodontoblast cell. - BTO:0001769 - CALOHA:TS-0696 - FMA:62999 - cell - legacy def: One of the cells forming the outer surface of dental pulp that produces tooth dentin. - odontoblast - - - - Skeletogenic cell that secretes dentine matrix, is derived from the odontogenic papilla, and develops from a preodontoblast cell. - GO_REF:0000034 - ISBN:0618947256 - @@ -1670,22 +515,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Skeletogenic cell that produces cementum (a bony substance that covers the root of a tooth), is part of the odontogenic papilla, and develops from a precementoblast cell. - CL:0000859 - CALOHA:TS-1164 - FMA:63002 - cementum secreting cell - cell - Legacy def: A cell of ectomesenchymal origin that aids in the formation the cementum layer on the roots of teeth. - cementoblast - - - - Skeletogenic cell that produces cementum (a bony substance that covers the root of a tooth), is part of the odontogenic papilla, and develops from a precementoblast cell. - GO_REF:0000034 - ISBN:0781733901 - @@ -1694,43 +524,13 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Skeletogenic cell that secretes osteoid, is capable of producing mineralized (hydroxyapatite) matrix, is located adjacent to or within osteoid tissue, and arises from the transformation of a preosteoblast cell. - BTO:0001593 - CALOHA:TS-0720 - FMA:66780 - cell - non-encoded relationships from VSAO - capable_of_producing VSAO:0000020 - osteoblast - - - - Skeletogenic cell that secretes osteoid, is capable of producing mineralized (hydroxyapatite) matrix, is located adjacent to or within osteoid tissue, and arises from the transformation of a preosteoblast cell. - GO_REF:0000034 - MESH:A11.329.629 - - - OBSOLETE: A classification of cells by their microscopic appearance. - CL:0000000 - CL:0000003 - CL:0001034 - cell - This term was made obsolete because there is no difference in meaning between it and 'cell', as any cell can be classified by its microscopic appearance. If you have used this term in annotation, please replace it with cell (CL:0000000), native cell (CL:0000003), or cell in vitro (CL:0001034) as appropriate. - obsolete cell by histology - true - - - - - OBSOLETE: A classification of cells by their microscopic appearance. - FB:ma - GOC:tfm - + @@ -1738,18 +538,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell that has a filiform extrusion of the cell surface. - VHOG:0001532 - XAO:0000031 - cell - ciliated cell - - - - A cell that has a filiform extrusion of the cell surface. - GOC:tfm - @@ -1758,21 +547,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A neurectoderm derived cell that lines the neural lumen. - BTO:0001724 - FMA:70550 - ependymocyte - cell - ependymal cell - - - - A neurectoderm derived cell that lines the neural lumen. - GOC:tfm - JB:jb - PMID:9550134 - @@ -1780,25 +555,8 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina. - BTO:0000414 - CALOHA:TS-2026 - CARO:0000077 - FBbt:00000124 - FMA:66768 - WBbt:0003672 - epitheliocyte - cell - epithelial cell - - - - - A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina. - FB:ma - GOC:tfm - MESH:A11.436 - + + @@ -1807,17 +565,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An epithelial cell that has a cillia. - FMA:70605 - cell - ciliated epithelial cell - - - - An epithelial cell that has a cillia. - GOC:tfm - @@ -1826,8 +574,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - duct epithelial cell @@ -1836,19 +582,13 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - branched duct epithelial cell - - cell - obsolete epithelial cell of gland - true - + @@ -1857,17 +597,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An endothelial cell that lines the vasculature. - cuboidal endothelial cell of vascular tree - cell - blood vessel endothelial cell - - - - An endothelial cell that lines the vasculature. - GOC:tfm - @@ -1876,8 +606,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - non-branched duct epithelial cell @@ -1887,28 +615,13 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - barrier epithelial cell - - Obsolete. Use PO:0000066 from Plant Ontology instead. A cell that constitutes the mesophyll of a hydathode and is located between the xylem endings and the epidermis. Proposed to be involved in the retrieval of solutes from the xylem sap. - cell - replaced_by: PO:0000066 - obsolete epithem cell - true - - - - - Obsolete. Use PO:0000066 from Plant Ontology instead. A cell that constitutes the mesophyll of a hydathode and is located between the xylem endings and the epidermis. Proposed to be involved in the retrieval of solutes from the xylem sap. - ISBN:0471245208 - PMID:12662305 - + @@ -1917,8 +630,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - columnar/cuboidal epithelial cell @@ -1927,9 +638,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - CALOHA:TS-1249 - cell - squamous epithelial cell @@ -1940,19 +648,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A flattened epithelial cell of mesenchymal origin that lines the serous cavity. - FMA:66773 - mesotheliocyte - cell - mesothelial cell - - - - A flattened epithelial cell of mesenchymal origin that lines the serous cavity. - GOC:tfm - ISBN:0721662544 - @@ -1961,8 +657,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - peridermal cell @@ -1972,8 +666,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - stratified epithelial cell @@ -1982,16 +674,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell which moves among different tissues of the body, via blood, lymph, or other medium. - cell - circulating cell - - - - A cell which moves among different tissues of the body, via blood, lymph, or other medium. - GOC:add - @@ -1999,18 +682,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell found predominately in the blood. - FMA:62844 - cell - blood cell - - - - A cell found predominately in the blood. - GOC:add - GOC:tfm - @@ -2018,10 +690,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - BTO:0004299 - lung epithelial cell - cell - epithelial cell of lung @@ -2031,19 +699,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An epithelial cell of the pancreas. - BTO:0000028 - pancreas epithelial cell - pancreatic epithelial cell - cell - epithelial cell of pancreas - - - - An epithelial cell of the pancreas. - GOC:tfm - @@ -2051,29 +707,9 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex. - CL:0000804 - CL:0000812 - BTO:0000782 - CALOHA:TS-1001 - FMA:62870 - VHOG:0001479 - T lymphocyte - T-cell - T-lymphocyte - cell - immature T cell - mature T cell - T cell - - - - - A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex. - GOC:add - GOC:tfm - ISBN:0781735149 - + + + @@ -2081,8 +717,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - germ line stem cell (sensu Vertebrata) @@ -2091,9 +725,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - FBbt:00004861 - cell - germ line stem cell (sensu Nematoda and Protostomia) @@ -2103,9 +734,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - FBbt:00004929 - cell - male germ line stem cell (sensu Nematoda and Protostomia) @@ -2115,9 +743,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - FBbt:00004873 - cell - female germ line stem cell (sensu Nematoda and Protostomia) @@ -2127,16 +752,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - spermatogonial stem cell - cell - male germ line stem cell (sensu Vertebrata) - - - - spermatogonial stem cell - PMID:19948499 - @@ -2145,8 +761,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - female germ line stem cell (sensu Vertebrata) @@ -2155,31 +769,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A tissue-resident macrophage of the reticuloendothelial system found on the luminal surface of the hepatic sinusoids involved in erythrocyte clearance. Markers include F4/80+, CD11b-low, CD68-positive, sialoadhesin-positive, CD163/SRCR-positive. Irregular, with long processes including lamellipodia extending into the sinusoid lumen, have flattened nucleus with cytoplasm containing characteristic invaginations of the plasma membrane (vermiform bodies); lie within the sinusoid lumen attached to the endothelial surface; derived from the bone marrow, form a major part of the body's mononuclear phagocyte system. - BTO:0000685 - FMA:14656 - hepatic macrophage - littoral cell of hepatic sinusoid - liver macrophage - macrophagocytus stellatus - stellate cell of von Kupffer - von Kupffer cell - cell - Markers: Mouse: F4/80+, CD11b-low, CD68+, sialoadhesin+, CD163/SRCR+; role or process: immune, antigen-presentation, clearance of senescent erythrocytes, iron metabolism. Kupffer cells are also reportedly C3aR-positive, CD14-low, CD54-positive, CD88-positive, and CD284-positive. They are also capable of producing IL-1, IL-6, TNF-alpha, nitric oxide, PGD2, PGE2, PGF2alpha, and TXA2. - Kupffer cell - - - - - A tissue-resident macrophage of the reticuloendothelial system found on the luminal surface of the hepatic sinusoids involved in erythrocyte clearance. Markers include F4/80+, CD11b-low, CD68-positive, sialoadhesin-positive, CD163/SRCR-positive. Irregular, with long processes including lamellipodia extending into the sinusoid lumen, have flattened nucleus with cytoplasm containing characteristic invaginations of the plasma membrane (vermiform bodies); lie within the sinusoid lumen attached to the endothelial surface; derived from the bone marrow, form a major part of the body's mononuclear phagocyte system. - GOC:add - GOC:tfm - GO_REF:0000031 - ISBN:0517223651 - MESH:A11.329.372.588 - PMID:15771589 - PMID:17105582 - + @@ -2188,39 +778,13 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, which typically differentiates from monocytes. This cell has the following markers: tartrate-resistant acid phosphatase type 5-positive, PU.1-positive, c-fos-positive, nuclear factor NF-kappa-B p100 subunit-positive, tumor necrosis factor receptor superfamily member 11A-positive and macrophage colony-stimulating factor 1 receptor-positive. - BTO:0000968 - CALOHA:TS-0721 - FMA:66781 - cell - chondroclast - Morphology: Highly vesicular; markers: Surface: RANK, cFMS (MCSF receptor); Secreted: cathepsin K and TRAP (tartate resistant acid phosphatase); transcription factors: PU.1, cFOS, MITF, NFkB (p52); role or process: tissue remodelling: bone resorption; lineage: hematopoietic, myeloid. - osteoclast - - - - - A specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, which typically differentiates from monocytes. This cell has the following markers: tartrate-resistant acid phosphatase type 5-positive, PU.1-positive, c-fos-positive, nuclear factor NF-kappa-B p100 subunit-positive, tumor necrosis factor receptor superfamily member 11A-positive and macrophage colony-stimulating factor 1 receptor-positive. - GOC:add - GOC:tfm - GO_REF:0000031 - ISBN:0781735149 - PMID:10428500 - PMID:15055519 - PMID:17380158 - + - - OBSOLETE (was not defined before being made obsolete). - cell - Consider using 'osteoclast ; CL:0000092' instead. - obsolete osteochondroclast - true - + @@ -2229,27 +793,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A leukocyte with abundant granules in the cytoplasm. - BTO:0000539 - BTO:0001026 - CALOHA:TS-0422 - FMA:62854 - granular leucocyte - granular leukocyte - polymorphonuclear leukocyte - cell - granulocyte - - - - - A leukocyte with abundant granules in the cytoplasm. - GOC:amm - GOC:tfm - MESH:A11.118.637.415 - MESH:D006098 - http://en.wikipedia.org/wiki/Granulocyte - + @@ -2257,8 +801,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - neuron associated cell @@ -2269,38 +811,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A fully differentiated neutrophil, a granular leukocyte having a nucleus with three to five lobes connected by slender threads, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes. They are produced in bone marrow at a rate of 5e10-10e10/day and have a half-life of 6-8 hours. Neutrophils are CD15-positive, CD16-positive, CD32-positive, CD43-positive, CD181-positive, and CD182-positive. - poly - polymorphonuclear leucocyte - polymorphonuclear leukocyte - BTO:0003473 - PMN - mature neutrocyte - mature neutrophil leucocyte - mature neutrophil leukocyte - mature neutrophilic leucocyte - mature neutrophilic leukocyte - polymorphonuclear neutrophil - polynuclear neutrophilic leucocyte - polynuclear neutrophilic leukocyte - cell - Neutrophils are also capable of secreting GRO-alpha, IL-1beta, IL-1ra, IL-3, IL-12, IP-10, MIG, MIP-1alpha, MIP-1beta, TGF-beta, TNF-alpha, VEGF, and anti-microbial peptides. They can positively influence the chemotaxis of basophils, T-cells, monocytes, macrophages, dendritic cells, and other neutrophils. Neutrophils are also CD35-positive, CD64-positive, CD89-positive, CD184-positive, and fMLP receptor-positive Ly-6G-positive (mouse), TLR2-low, TLR4-low, and lineage-negative (CD2, CD3, CD5, CD9, CD19, CD36, CD49d, CD56, CD61, CD235a (glycophorin-A)). - mature neutrophil - - - - - A fully differentiated neutrophil, a granular leukocyte having a nucleus with three to five lobes connected by slender threads, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes. They are produced in bone marrow at a rate of 5e10-10e10/day and have a half-life of 6-8 hours. Neutrophils are CD15-positive, CD16-positive, CD32-positive, CD43-positive, CD181-positive, and CD182-positive. - GOC:add - GOC:tfm - MESH:A11.118.637.415.583 - MESH:D009504 - PMID:11138776 - PMID:12560239 - PMID:15514007 - PMID:7880385 - http://www.cap.org - + @@ -2309,54 +820,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation. Progenitors leave bone marrow and mature in connective and mucosal tissue. Mature mast cells are found in all tissues, except the bloodstream. Their phenotype is CD117-high, CD123-negative, CD193-positive, CD200R3-positive, and FceRI-high. Stem-cell factor (KIT-ligand; SCF) is the main controlling signal of their survival and development. - BTO:0000830 - CALOHA:TS-0603 - FMA:66784 - histaminocyte - labrocyte - mastocyte - cell - tissue basophil - Mast cells are generally integrin beta-7-negative and positive for TLR2, TLR3, TLR4, TLR5, TLR7, TLR9, C3aR, C5aR, CR3, CR4, VEGF, FGF2, and renin. They can express MHC Class I and II on their surface. Activated murine mast cells (IgE+Antigen) were capable of expressing the following co-stimulatory molecules: CD95 (Fas), CD120b, CD137 (4-1BB), CD153 (CD30L), CD154 (CD40L), GITR, ICOSL, OX40L, PD-L1, and PD-L2. Note that there was some mouse strain variation. Mast cells have also been demonstrated to produce bFGF, CCL2, CCL4, CCL5, CCL11, CCL20, CXCL2, CXCL8, CXCL10, GM-CSF, IFN-gamma, IL-1, IL-2, IL-3, IL-8, IL-10, IL-11, IL-12, IL-13, IL-16, IL-25, IL-18, MIP-1, prostaglandin D2, SCF, TGF-beta, TNF-alpha, TSLP, VEGF, and XCL1. They express the transcription factors Transcription factors AP-1, GATA1, MITF, Notch2, PIAS3, PU.1, and STAT5. - mast cell - - - - - A cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation. Progenitors leave bone marrow and mature in connective and mucosal tissue. Mature mast cells are found in all tissues, except the bloodstream. Their phenotype is CD117-high, CD123-negative, CD193-positive, CD200R3-positive, and FceRI-high. Stem-cell factor (KIT-ligand; SCF) is the main controlling signal of their survival and development. - GOC:add - GOC:dsd - GOC:tfm - ISBN:068340007X - MESH:A11.329.427 - MESH:D008407 - PMCID:PMC1312421 - PMCID:PMC2855166 - PMID:15153310 - PMID:16455980 - PMID:19671378 - PMID:212366338 - PMID:9354811 - - - - - labrocyte - ISBN:0721601464 - - - - - mastocyte - ISBN:0721601464 - - - - - tissue basophil - ISBN:068340007X - + @@ -2366,21 +830,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A specialized epithelial cell involved in sensory perception. Restricted to special sense organs of the olfactory, gustatory, and vestibulocochlear receptor systems; contain sensory cells surrounded by supportive, non-receptive cells. - neuroepithelial cell - BTO:0004301 - cell - The term "neuroepithelial cell" is used to describe both this cell type and neurecto-epithelial cell (CL:0000710). - sensory epithelial cell - - - - A specialized epithelial cell involved in sensory perception. Restricted to special sense organs of the olfactory, gustatory, and vestibulocochlear receptor systems; contain sensory cells surrounded by supportive, non-receptive cells. - GOC:tfm - ISBN:0517223651 - ISBN:0721662544 - @@ -2388,21 +838,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Most generally any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions. - BTO:0003811 - FBbt:00005125 - FMA:67313 - WBbt:0005113 - cell - interneuron - - - - Most generally any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions. - GOC:tfm - MESH:A08.663.358 - @@ -2410,22 +846,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes or inhibits movement. - BTO:0000312 - FMA:83617 - WBbt:0005409 - motoneuron - anterior horn cell - cell - motor neuron - - - - An efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes or inhibits movement. - MESH:A08.663.655.500 - PMID:16875686 - @@ -2433,20 +854,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Any neuron having a sensory function; an afferent neuron conveying sensory impulses. - BTO:0001037 - FBbt:00005124 - FMA:84649 - WBbt:0005759 - cell - sensory neuron - - - - Any neuron having a sensory function; an afferent neuron conveying sensory impulses. - ISBN:0721662544 - @@ -2454,8 +862,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - polymodal neuron @@ -2464,18 +870,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A type of interneuron that has two neurites, usually an axon and a dendrite, extending from opposite poles of an ovoid cell body. - FMA:67282 - cell - bipolar neuron - - - - A type of interneuron that has two neurites, usually an axon and a dendrite, extending from opposite poles of an ovoid cell body. - GOC:tfm - ISBN:0444009442 - @@ -2483,18 +878,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Neuron with an axon and two or more dendrites. - FMA:67287 - cell - multipolar neuron - - - - Neuron with an axon and two or more dendrites. - FMA:67287 - GOC:tfm - @@ -2502,18 +886,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Neuron with two neurites that are fused grossly when they protrude from the soma and bifurcate a short distance from the soma. - FMA:67305 - cell - pseudounipolar neuron - - - - Neuron with two neurites that are fused grossly when they protrude from the soma and bifurcate a short distance from the soma. - FMA:67305 - GOC:tfm - @@ -2521,18 +894,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Neuron with one neurite that extends from the cell body. - FMA:67278 - cell - unipolar neuron - - - - Neuron with one neurite that extends from the cell body. - FMA:67278 - GOC:nv - @@ -2540,17 +902,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A neruon whose cell body is within an autonomic ganglion. - FMA:80121 - cell - autonomic neuron - - - - A neruon whose cell body is within an autonomic ganglion. - GOC:tfm - @@ -2558,19 +910,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A neuron that uses acetylcholine as a vesicular neurotransmitter. - BTO:0004902 - FMA:84796 - WBbt:0006840 - cell - cholinergic neuron - - - - A neuron that uses acetylcholine as a vesicular neurotransmitter. - GOC:tfm - @@ -2578,8 +918,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - adrenergic neuron @@ -2588,8 +926,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - peptidergic neuron @@ -2598,17 +934,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A neuron that is part of nerve found outside the central nervous system. - FMA:84664 - cell - peripheral neuron - - - - A neuron that is part of nerve found outside the central nervous system. - ISBN:0721662544 - @@ -2616,9 +942,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - columnar neuron - columnar neuron @@ -2628,19 +951,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A vertebrate phagocyte with a single nucleus. - BTO:0001433 - cell - mononuclear phagocyte - - - - A vertebrate phagocyte with a single nucleus. - GOC:add - GOC:tfm - ISBN:0781735149 - @@ -2648,11 +959,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - FMA:72552 - cell of surface ectoderm - surface ectoderm cell - cell - surface ectodermal cell @@ -2662,25 +968,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm. - BTO:0001176 - CALOHA:TS-0278 - FMA:66772 - endotheliocyte - cell - From FMA: 9.07.2001: Endothelial cell has always been classified as a kind of epithelial cell, specifically a squamous cell but that is not true. First, endothelial cell can either be squamous or cuboidal (e.g. high-endothelial cell) and secondly, it has different embryological derivation (mesodermal) than a true epithelial cell (ectodermal and endodermal). The basis for present classification is the fact that it comprises the outermost layer or lining of anatomical structures (location-based) but a better structural basis for the differentia is the cytoskeleton of the cell. Endothelial cell has vimentin filaments while an epithelial cell has keratin filaments. [Onard]. - endothelial cell - - - - - An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm. - GOC:tfm - MESH:D042783 - PMID:21275341 - http://en.wikipedia.org/wiki/Endothelial_cell - https://sourceforge.net/tracker/?func=detail&atid=440764&aid=3364936&group_id=36855 - + @@ -2688,18 +976,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Pioneer neurons establish a pathway in the developing central nervous system and then undergo programmed cell death once the adult axons, which follow them, have made connections with the target site. Thus, they are a transient cell type involved in axon guidance. - FBbt:00005128 - cell - pioneer neuron - - - - Pioneer neurons establish a pathway in the developing central nervous system and then undergo programmed cell death once the adult axons, which follow them, have made connections with the target site. Thus, they are a transient cell type involved in axon guidance. - GOC:cvs - GOC:tfm - @@ -2707,8 +984,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - CNS neuron (sensu Vertebrata) @@ -2717,8 +992,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - basket cell @@ -2729,20 +1002,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Large intrinsic neuron located in the granule layer of the cerebellar cortex that extends its dendrites into the molecular layer where they receive contact from parallel fibers. The axon of the Golgi cell enters ramifies densely in the granule layer and enters into a complex arrangement with mossy fiber terminals and granule cell dendrites to form the cerebellar glomerulus. Llinas, Walton and Lang. In The Synaptic Organization of the Brain. 5th ed. 2004. - Golgi cell - Golgi neuron - cerebellar Golgi neuron - cerebellum Golgi cell - cell - cerebellar Golgi cell - - - - Large intrinsic neuron located in the granule layer of the cerebellar cortex that extends its dendrites into the molecular layer where they receive contact from parallel fibers. The axon of the Golgi cell enters ramifies densely in the granule layer and enters into a complex arrangement with mossy fiber terminals and granule cell dendrites to form the cerebellar glomerulus. Llinas, Walton and Lang. In The Synaptic Organization of the Brain. 5th ed. 2004. - NIFSTD:sao1415726815 - @@ -2750,9 +1010,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - BTO:0003393 - cell - granule cell @@ -2763,23 +1020,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - The output neuron of the cerebellar cortex. - BTO:0001011 - CALOHA:TS-0845 - FMA:67969 - Purkinje neuron - Purkinje's cell - cerebellar Purkinje cell - cerebellum Purkinje cell - cell - Purkinje cell - - - - - The output neuron of the cerebellar cortex. - MESH:A08.186.211.132.810.428.200.212.600 - + @@ -2787,9 +1028,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - BTO:0002316 - cell - stellate neuron @@ -2798,8 +1036,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - neuron associated cell (sensu Vertebrata) @@ -2808,9 +1044,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - FBbt:00005144 - cell - glial cell (sensu Nematoda and Protostomia) @@ -2819,21 +1052,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Guide neuronal migration during development, and exchange metabolites with neurons. - BTO:0002606 - CALOHA:TS-0415 - FMA:54536 - neuroglial cell - cell - neuroglia - glial cell - - - - A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Guide neuronal migration during development, and exchange metabolites with neurons. - MESH:A08.637 - @@ -2841,21 +1060,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A neuroglial cell of ectodermal origin, i.e., the astrocytes and oligodendrocytes considered together. - BTO:0000771 - CALOHA:TS-2027 - FMA:54538 - macrogliocyte - cell - macroglial cell - - - - A neuroglial cell of ectodermal origin, i.e., the astrocytes and oligodendrocytes considered together. - GOC:tfm - ISBN:0721662544 - @@ -2863,29 +1068,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from 'star' cells) are irregularly shaped with many long processes, including those with 'end feet' which form the glial (limiting) membrane and directly and indirectly contribute to the blood-brain barrier. They regulate the extracellular ionic and chemical environment, and 'reactive astrocytes' (along with microglia) respond to injury. - BTO:0000099 - CALOHA:TS-0060 - FMA:54537 - astrocytic glia - cell - Astrocytes are reportedly CD68-negative, CD121a-positive, CD184-positive, CD192-positive, CRF-positive, EGFR-positive, GFAP-positive, GLUT1-positive, MBP-negative, and NGFR-positive. - astrocyte - - - - - A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from 'star' cells) are irregularly shaped with many long processes, including those with 'end feet' which form the glial (limiting) membrane and directly and indirectly contribute to the blood-brain barrier. They regulate the extracellular ionic and chemical environment, and 'reactive astrocytes' (along with microglia) respond to injury. - GOC:dsd - GOC:tfm - MESH:A08.637.200 - MESH:D001253 - PMID:11746784 - PMID:12162730 - PMID:12898703 - PMID:20942978 - http://en.wikipedia.org/wiki/Astrocyte - + @@ -2893,30 +1076,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A class of large neuroglial (macroglial) cells in the central nervous system. Form the insulating myelin sheath of axons in the central nervous system. - BTO:0000962 - CALOHA:TS-0709 - FMA:54540 - OLs - cell - oligodendroglia - Oligodendrocytes are reportedly MDP-positive and CD4-negative. - oligodendrocyte - - - - - A class of large neuroglial (macroglial) cells in the central nervous system. Form the insulating myelin sheath of axons in the central nervous system. - MESH:A08.637.600 - MESH:D009836 - http://en.wikipedia.org/wiki/Oligodendrocyte - - - - - OLs - PMID:8734446 - + @@ -2925,51 +1085,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A central nervous system macrophage found in the parenchyma of the central nervous system. Marker include CD11b-positive, F4/80-positive, and CD68-positive. - brain macrophage - BTO:0000078 - BTO:0000962 - FMA:54539 - FMA:54540 - brain-resident macrophage - hortega cells - microglia - microgliocyte - cell - MF.microglia.CNS - Markers: Mouse: CD11b+, F4/80+, CD68+. They represent ~12% of the cells in the CNS, but they are not uniformly distributed within the CNS. A normal adult mouse brain has approximately 3.5x10e6 microglia. Microglia are also reportedly CD3-negative, CD4-positive, CD8-negative, CD11b-positive, CD11c-high, CD14-negative, CD19-negative, CD45-low, CD56-negative, CD163-negative, CD200R-positive, CD281-positive, CD282-positive, CD283-positive, CD284-positive, CD285-positive, CD286-positive, CD287-positive, CD288-positive, CD289-positive, Gr1-negative, nestin-positive, and PU.1-positive. - microglial cell - - - - - A central nervous system macrophage found in the parenchyma of the central nervous system. Marker include CD11b-positive, F4/80-positive, and CD68-positive. - GOC:add - GOC:dsd - GOC:tfm - ISBN:0721601464 - MESH:D017628 - PMID:11517395 - PMID:12430718 - PMID:14561199 - PMID:14612429 - PMID:16177057 - PMID:19461673 - PMID:2089275 - http://en.wikipedia.org/wiki/Microglia - - - - - hortega cells - http://www.copewithcytokines.de/ - - - - - microgliocyte - http://www.copewithcytokines.de/ - + @@ -2977,8 +1093,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - neuron associated cell (sensu Nematoda and Protostomia) @@ -2987,8 +1101,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - gut endothelial cell @@ -2998,19 +1110,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Cell of the single layer of large flattened cells covering the surface of the cornea. - CALOHA:TS-0172 - FMA:70614 - cell - corneal endothelial cell - - - - Cell of the single layer of large flattened cells covering the surface of the cornea. - GOC:tfm - MESH:A09.371.060.067.31 - @@ -3018,18 +1118,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Ectoderm destined to be nervous tissue. - neurectoderm cell - cell - neurectodermal cell - - - - Ectoderm destined to be nervous tissue. - GOC:tfm - ISBN:068340007X - @@ -3039,73 +1128,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. This cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs. - CL:0002452 - BTO:0002625 - BTO:0003298 - FMA:70546 - BMSC - bone marrow stromal cells - colony-forming unit-fibroblast - marrow stromal cells - cell - CFU-F - MSC - mesenchymal precursor cell - mesenchymal progenitor cells - mesenchymal stem cell - mesenchymal stromal cell - mesenchymal stromal cells - stem cells, mesenchymal - Many but not all mesenchymal cells derive from the mesoderm. MSCs are reportedly CD3-negative, CD4-negative, CD5-negative, CD8-negative, CD11a-negative, CD11b-negative, CD14-negative, CD19-negative, CD29-positive, CD31-negative, CD34-negative, CD38-negative, CD40-negative, CD44-positive, CD45-negative, CD49-positive, CD54-positive, CD66b-negative, CD79a-negative, CD80-negative, CD102-positive, CD106-positive, CD117-positive, CD121a-positive, CD121b-positive, CD123-positive, CD124-positive, CD133-negative, CD146-positive, CD166-positive, CD271-positive, B220-negative, Gr1-negative, MHCI-positive, MHCII-negative, SSEA4-negative, sca1-positive, Ter119-negative, and glycophorin A-negative. Cultured MSCs are capable of producing stem cell factor, IL7, IL8, IL11, TGF-beta, cofilin, galectin-1, laminin-receptor 1, cyclophilin A, and MMP-2. - mesenchymal stem cell - - - - - A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. This cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs. - FB:ma - GOC:dsd - PMCID:PMC2613570 - PMID:10102814j - PMID:16923606 - PMID:17986482 - PMID:19960544 - http://en.wikipedia.org/wiki/Mesenchymal_stem_cell - http://www.copewithcytokines.de/cope.cgi?key=mesenchymal%20stem%20cells - - - - - marrow stromal cells - PMID:11378515 - - - - - MSC - PMID:11378515 - - - - - mesenchymal progenitor cells - MESH:D044982 - - - - - - mesenchymal stromal cells - - - - - - stem cells, mesenchymal - MESH:D044982 - - + @@ -3113,28 +1136,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An inactive fibroblast; cytoplasm is sparse, endoplasmic reticulum is scanty with flattened nucleus. Term used by some histologists; when fibroblasts become relatively inactive in fiber formation. However, this cell has the potential for fibrogenesis in quiescent connective tissue of the adult, as well as during development, other histologists prefer to use the term fibroblast in all circumstances. These cells represent ~0.5% of peripheral blood leukocytes. - FMA:63879 - cell - Cultured human fibrocytes are MHCI-positive, MHCII-positive, CD1a-negative, CD3-negative, CD4-negative, CD8-negative, CD10-negative, CD11b-positive, CD13-positive, CD14-negative, CD16-negative, CD18-positive, CD19-negative, CD25-negative, CD29-positive, CD32-positive, CD33-negative, CD34-positive, CD38-negative, CD40-positive, CD44-negative, CD45RO-positive, CD49a-positive, CD49b-positive, CD49c-negative, CD49d-negative, CD49e-positive, CD49f-negative, CD56-negative, CD58-positive, CD61-positive, CD64-positive, CD70-negative, CD71-positive, CD80-positive, CD83-negative, CD86-positive, CD103-negative, CD105-positive, CD181-positive, CD182-negative, CD183-positive, CD184-positive, CD185-negative, CD186-negative, CD191-positive, CD192-negative, CD193-positive, CD194-positive, CD195-positive, CD196-negative, CD197-positive, CD199-positive, desmin-negative, F4/80-positive, Gr1-positive, LSP-1-positive, MHCI-positive, MHCII-positive, alpha-SMA-negative, TCRab-negative, TCRgd-negative, and vimentin-positive. Fibrocytes are also capable of secreting angiogenin, bFGF, CCL2, CCL3, CCL4, CCL8, CXCL1, type I collagen, type III collagen, CTGF, fibronectin, GM-CSF, IL-1a, IL-6, IL-8, IL-10, M-CSF, MMP-9, PDGF-A, TGF-alpha, TGF-beta1, TNF-alpha, and VEGF-A. - fibrocyte - - - - - An inactive fibroblast; cytoplasm is sparse, endoplasmic reticulum is scanty with flattened nucleus. Term used by some histologists; when fibroblasts become relatively inactive in fiber formation. However, this cell has the potential for fibrogenesis in quiescent connective tissue of the adult, as well as during development, other histologists prefer to use the term fibroblast in all circumstances. These cells represent ~0.5% of peripheral blood leukocytes. - GOC:dsd - GOC:tfm - ISBN:0412046911 - ISBN:0517223651 - PMID:11641248 - PMID:15010326 - PMID:17607298 - PMID:18222966 - PMID:8790603 - PMID:9551999 - http://en.wikipedia.org/wiki/Fibrocyte - + @@ -3143,22 +1145,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals. Fat is usually stored in the form of triglycerides. - CL:0000450 - BTO:0000443 - CALOHA:TS-0012 - FMA:63880 - adipocyte - adipose cell - cell - fat cell - - - - A fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals. Fat is usually stored in the form of triglycerides. - MESH:A11.329.114 - @@ -3166,23 +1153,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A mature osteoblast that has become embedded in the bone matrix. They occupy a small cavity, called lacuna, in the matrix and are connected to adjacent osteocytes via protoplasmic projections called canaliculi. - bone cell - BTO:0002038 - CALOHA:TS-1167 - FMA:66779 - VSAO:0000124 - cell - VSAO relationship simplified OBO_REL:integral_part_of VSAO:0000118 - osteocyte - - - - - A mature osteoblast that has become embedded in the bone matrix. They occupy a small cavity, called lacuna, in the matrix and are connected to adjacent osteocytes via protoplasmic projections called canaliculi. - GOC:tfm - MESH:A11.329.629.500 - + @@ -3191,21 +1162,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Skeletogenic cell that is terminally differentiated, secretes an avascular, GAG-rich matrix, is embedded in cartilage tissue matrix, retains the ability to divide, and develops from a chondroblast cell. - BTO:0000249 - CALOHA:TS-0138 - FMA:66782 - cartilage cell - cell - chondrocyte - - - - Skeletogenic cell that is terminally differentiated, secretes an avascular, GAG-rich matrix, is embedded in cartilage tissue matrix, retains the ability to divide, and develops from a chondroblast cell. - GO_REF:0000034 - MESH:A11.329.171 - @@ -3213,16 +1170,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Skeletogenic cell that secretes dentine matrix, is derived from odontogenic papilla. Embedded in dentine tissue, and is the transformation of a non-terminally differentiated odontoblast cell. - cell - odontocyte - - - - Skeletogenic cell that secretes dentine matrix, is derived from odontogenic papilla. Embedded in dentine tissue, and is the transformation of a non-terminally differentiated odontoblast cell. - GO_REF:0000034 - @@ -3230,18 +1178,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An osteocytelike cell with numerous processes, trapped in a lacuna in the cement of the tooth. - FMA:63003 - cell - CHECK: wikipedia says that cementocytes no longer produce cementum, but the phenoscape def is: Skeletogenic cell that produces cementum, is part of the odontogenic papilla, and is a transformation of a cementoblast cell (no change to existing def). - cementocyte - - - - An osteocytelike cell with numerous processes, trapped in a lacuna in the cement of the tooth. - ISBN:0781733901 - @@ -3249,20 +1186,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell occurring in the peripheral part of the vitreous body of the eye that may be responsible for production of hyaluronic acid and collagen. - BTO:0004271 - FMA:70620 - cell - vitreous cell - hyalocyte - - - - A cell occurring in the peripheral part of the vitreous body of the eye that may be responsible for production of hyaluronic acid and collagen. - GOC:tfm - PMID:19073178 - @@ -3270,30 +1194,13 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - guidepost cell - - OBSOLETE: A classification of cells by their primary end goal or behavior. - CL:0000000 - CL:0000003 - CL:0001034 - cell - This term was made obsolete because there is no difference in meaning between it and 'cell', as any cell can be classified by its function or behavior. If you have used this term in annotation, please replace it with cell (CL:0000000), native cell (CL:0000003), or cell in vitro (CL:0001034) as appropriate. - obsolete cell by function - true - - - - - OBSOLETE: A classification of cells by their primary end goal or behavior. - FB:ma - + @@ -3301,19 +1208,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response. - APC - cell - Note change of name; nearly all somatic cells can present antigens to T cells via MHC Class I complexes leading to effector responses, but professional antigen presenting cells constitutively express MHC Class II as well as costimulatory molecules, and thus can initiate immune responses via T cells. - professional antigen presenting cell - - - - A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response. - GOC:add - ISBN:0781735149 - @@ -3321,8 +1216,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - simple columnar epithelial cell @@ -3331,19 +1224,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A pigment cell is a cell that contains pigment granules. - VHOG:0001678 - chromatocyte - chromatophore - cell - pigment cell - - - - A pigment cell is a cell that contains pigment granules. - GOC:tfm - @@ -3352,22 +1233,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A pigment cell derived from the neural crest. Contains melanin-filled pigment granules, which gives a brown to black appearance. - CL:0000572 - BTO:0000847 - CALOHA:TS-0613 - FMA:70545 - VHOG:0001679 - melanophore - cell - melanocyte - - - - A pigment cell derived from the neural crest. Contains melanin-filled pigment granules, which gives a brown to black appearance. - SANBI:mhl - @@ -3375,9 +1241,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - pigment cell - cell - visual pigment cell @@ -3388,18 +1251,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A specialized epithelial cell that is capable of synthesizing and secreting certain biomolecules. - CALOHA:TS-2085 - FMA:86494 - cell - glandular epithelial cell - - - - A specialized epithelial cell that is capable of synthesizing and secreting certain biomolecules. - GOC:tfm - @@ -3407,19 +1259,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell that specializes in controlled release of one or more substances. - BTO:0003659 - FMA:86916 - cell - secretory cell - - - - A cell that specializes in controlled release of one or more substances. - GOC:tfm - ISBN:0721662544 - @@ -3427,17 +1267,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell of an exocrine gland; i.e. a gland that discharges its secretion via a duct. - FMA:16014 - cell - exocrine cell - - - - A cell of an exocrine gland; i.e. a gland that discharges its secretion via a duct. - ISBN:0198547684 - @@ -3446,18 +1276,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell that secretes glycosaminoglycans. - GAG secreting cell - hyaluronic acid secreting cell - cell - glycosaminoglycan secreting cell - - - - A cell that secretes glycosaminoglycans. - GOC:tfm - @@ -3465,8 +1284,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - protein secreting cell @@ -3476,33 +1293,13 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell that is usually basal in position, cuboidal with round nucleus, short microvilli, secretes pepsinogen. - FMA:62902 - chief cell of stomach - gastric chief cell - pepsinogen secreting cell - zymogenic cell - cell - peptic cell - - - - A cell that is usually basal in position, cuboidal with round nucleus, short microvilli, secretes pepsinogen. - GOC:tfm - - - OBSOLETE: A cell of the lymphoid series that can react with antigen to produce specific cell products called antibodies. Various cell subpopulations, often B cells, can be defined, based on the different classes of immunoglobulins that they synthesize. - cell - Consider using 'B cell ; CL:0000236' or one of its children instead. - obsolete antibody secreting cell - true - + @@ -3510,17 +1307,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell that specializes in secretion of surfactant in the alveoli of the lung. - cell - surfactant secreting cell - - - - A cell that specializes in secretion of surfactant in the alveoli of the lung. - GOC:tfm - ISBN:0721662544 - @@ -3529,22 +1316,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Epithelial progenitor cell of the lung. Clara cells are dome-shaped with short microvilli but no cilia. They function to protect the bronchiolar epithelium. Clara cells also multiply and differentiate into ciliated cells to regenerate the bronchiolar epithelium. - BTO:0004811 - FMA:14119 - Clara cell of bronchiole - bronchiolar non-ciliated cell - cell - Clara cell - - - - Epithelial progenitor cell of the lung. Clara cells are dome-shaped with short microvilli but no cilia. They function to protect the bronchiolar epithelium. Clara cells also multiply and differentiate into ciliated cells to regenerate the bronchiolar epithelium. - GOC:tfm - PMID:12107102 - PMID:7905712 - @@ -3552,8 +1324,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - seromucus secreting cell @@ -3563,20 +1333,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell of the epithelial lining that produce and secrete mucins. - BTO:0001540 - FMA:13148 - http://en.wikipedia.org/wiki/Goblet_cell - chalice cell - cell - goblet cell - - - - A cell of the epithelial lining that produce and secrete mucins. - MESH:A03.492.411.369.320 - @@ -3584,8 +1341,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - acid secreting cell @@ -3595,20 +1350,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A large, oval stomach epithelial cell with a central nucleus; source of gastric acid. Secretes HCl. - BTO:0001780 - FMA:62901 - oxyntic cell - cell - parietal cell - - - - A large, oval stomach epithelial cell with a central nucleus; source of gastric acid. Secretes HCl. - GOC:tfm - ISBN:0517223651 - @@ -3616,18 +1358,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell of an endocrine gland, ductless glands that secrete substances which are released directly into the circulation and which influence metabolism and other body functions. - FMA:83809 - endocrinocyte - cell - endocrine cell - - - - A cell of an endocrine gland, ductless glands that secrete substances which are released directly into the circulation and which influence metabolism and other body functions. - MESH:A06.407 - @@ -3636,19 +1367,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An endocrine cell that is located in the epithelium of the gastrointestinal tract or in the pancreas. - BTO:0003865 - FMA:62930 - cell - enteroendocrine cell - - - - An endocrine cell that is located in the epithelium of the gastrointestinal tract or in the pancreas. - GOC:tfm - SANBI:mhl - @@ -3658,19 +1377,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An endocrine cell that has the specialized function to produce and secrete hormones in response to neuronal signals. - BTO:0002691 - FMA:83810 - neurosecretory cell - cell - neuroendocrine cell - - - - An endocrine cell that has the specialized function to produce and secrete hormones in response to neuronal signals. - MESH:A06.688 - @@ -3678,19 +1385,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell that stores epinephrine secretory vesicles. During times of stress, the nervous system signals the vesicles to secrete their hormonal content. Their name derives from their ability to stain a brownish color with chromic salts. Characteristically, they are located in the adrenal medulla and paraganglia of the sympathetic nervous system. - BTO:0000259 - FMA:69263 - phaeochromocyte - cell - chromaffin cell - - - - A cell that stores epinephrine secretory vesicles. During times of stress, the nervous system signals the vesicles to secrete their hormonal content. Their name derives from their ability to stain a brownish color with chromic salts. Characteristically, they are located in the adrenal medulla and paraganglia of the sympathetic nervous system. - MESH:A06.224.161 - @@ -3698,8 +1393,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - peptide hormone secreting cell @@ -3709,9 +1402,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - BTO:0000783 - cell - insulin secreting cell @@ -3723,88 +1413,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell that secretes insulin and is located towards the center of the islets of Langerhans. - beta cell - BTO:0000783 - EV:0200009 - FMA:70586 - MA:0002419 - ncithesaurus:Beta_Cell - B-cell of pancreatic islet - beta cell of pancreatic islet - insulin-secreting cell - pancreatic B cell - pancreatic B-cell - pancreatic beta cell - pancreatic islet core - type B enteroendocrine cell - cell - beta cell islet - Pancreatic beta cells are also reportedly CD284-positive. Upon activation, they upregulate their CD14 expression. - type B pancreatic cell - - - - - A cell that secretes insulin and is located towards the center of the islets of Langerhans. - GOC:tfm - ISBN:0517223651 - http://en.wikipedia.org/wiki/Pancreatic_b_cell - - - - - beta cell - ZFA:0009102 - - - - - B-cell of pancreatic islet - FMA:70586 - - - - - beta cell of pancreatic islet - FMA:70586 - - - - - insulin-secreting cell - FMA:70586 - - - - - pancreatic B-cell - FMA:70586 - - - - - pancreatic beta cell - FMA:70586 - - - - - pancreatic islet core - MA:0002419 - - - - - type B enteroendocrine cell - FMA:70586 - - - - - beta cell islet - MA:0002419 - + @@ -3812,18 +1421,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell that secretes glucagon. - FMA:84045 - glucagon-secreting cell - cell - glucagon secreting cell - - - - A cell that secretes glucagon. - GOC:tfm - @@ -3833,21 +1431,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A type of enteocrine cell found in the periphery of the islets of Langerhans that secretes glucagon. - BTO:0000990 - FMA:70585 - alpha cell of iselt of Langerhans - pancreatic alpha cell - cell - pancreatic A cell - - - - A type of enteocrine cell found in the periphery of the islets of Langerhans that secretes glucagon. - GOC:tfm - ISBN:0721662544 - @@ -3855,8 +1439,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - somatostatin secreting cell @@ -3867,25 +1449,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A D cell located in the pancreas. Peripherally placed within the islets like type A cells; contains somatostatin. - BTO:0000803 - FMA:70587 - D-cell of pancreatic islet - delta cell of islet - delta cell of pancreatic islet - pancreatic D-cell - pancreatic delta cell - somatostatin-secreting pancreatic cell - cell - pancreatic D cell - - - - - A D cell located in the pancreas. Peripherally placed within the islets like type A cells; contains somatostatin. - FMA:0517223651 - GOC:tfm - + @@ -3893,8 +1457,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - steroid hormone secreting cell @@ -3904,19 +1466,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A progesterone secreting cell in the corpus luteum. The large luteal cells develop from the granulosa cells. The small luteal cells develop from the theca cells. - BTO:0003939 - FMA:18688 - lutein cell - cell - luteal cell - - - - A progesterone secreting cell in the corpus luteum. The large luteal cells develop from the granulosa cells. The small luteal cells develop from the theca cells. - MESH:A05.360.319.114.630.278.400 - @@ -3924,8 +1474,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - ecdysteroid secreting cell @@ -3934,8 +1482,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - testosterone secreting cell @@ -3944,24 +1490,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis. - interstitial cell - BTO:0000755 - CALOHA:TS-1150 - EMAPA:29655 - FMA:72297 - interstitial cell of Leydig - cell - Note that the Amphibian Anatomy Ontology (AA) has a class 'leydig cells' but this is unrelated - Leydig cell - - - - - A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis. - GOC:tfm - PMID:12050120 - + @@ -3969,8 +1498,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - progesterone secreting cell @@ -3979,8 +1506,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - estradiol secreting cell @@ -3989,16 +1514,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell whose primary function is intermediary metabolism. - cell - metabolising cell - - - - A cell whose primary function is intermediary metabolism. - FB:ma - @@ -4009,24 +1525,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - The main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. Majority of cell population of liver, polygonal in shape, arranged in plates or trabeculae between sinusoids; may have single nucleus or binucleated. - BTO:0000575 - CALOHA:TS-0454 - FMA:14515 - cell - Hepatocytes are reportedly MHC Class I-positive and MHC Class II-positive. - hepatocyte - - - - - The main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. Majority of cell population of liver, polygonal in shape, arranged in plates or trabeculae between sinusoids; may have single nucleus or binucleated. - GOC:tfm - ISBN:0412046911 - MESH:A11.436.348 - PMID:19717280 - http://en.wikipedia.org/wiki/Hepatocyte - + @@ -4034,16 +1533,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell whose primary function is to shorten. - cell - contractile cell - - - - A cell whose primary function is to shorten. - FB:ma - @@ -4053,22 +1543,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Contractile cells resembling smooth muscle cells that are present in glands, notably the mammary gland, and aid in secretion. This cell has long weaving dendritic processes containing myofilament. - BTO:0002309 - CALOHA:TS-2379 - FMA:67799 - basket epithelial cell - myoepitheliocyte - cell - myoepithelial cell - - - - Contractile cells resembling smooth muscle cells that are present in glands, notably the mammary gland, and aid in secretion. This cell has long weaving dendritic processes containing myofilament. - GOC:tfm - ISBN:0721662544 - @@ -4078,28 +1553,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An animal cell that has characteristics of both a fibroblast cell and a smooth muscle cell. - MFB - cell - Myofibroblasts are alpha-SMA-positive, CD34-negative, CD45-negative. They are reportedly capable of secreting IL-1beta, IL-6, and TNF-alpha. - myofibroblast cell - - - - - An animal cell that has characteristics of both a fibroblast cell and a smooth muscle cell. - GOC:dsd - GOC:tfm - MESH:D058628 - PMID:19800625 - PMID:20630469 - - - - - MFB - PMID:8731193 - + @@ -4110,24 +1564,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns. - BTO:0000888 - BTO:0000902 - CALOHA:TS-2032 - FBbt:00005074 - FMA:67328 - WBbt:0003675 - muscle fiber - myocyte - cell - muscle cell - - - - - A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns. - MESH:A11.620 - + @@ -4135,20 +1572,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A somatic cell located in skeletal muscle. - BTO:0004392 - CALOHA:TS-2158 - FMA:9727 - skeletal muscle cell - cell - cell of skeletal muscle - - - - A somatic cell located in skeletal muscle. - GOC:tfm - @@ -4156,25 +1580,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A muscle cell that develops tension more slowly than a fast-twitch fiber. - FMA:84448 - cell - slow muscle fiber - slow muscle cell - - - - - A muscle cell that develops tension more slowly than a fast-twitch fiber. - GOC:tfm - ISBN:0323052908 - - - - - slow muscle fiber - ISBN:0815316208 - + @@ -4182,18 +1588,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A muscle cell that can develop high tension rapidly. It is usually innervated by a single alpha neuron . - glycolytic muscle fiber - cell - fast muscle cell - - - - A muscle cell that can develop high tension rapidly. It is usually innervated by a single alpha neuron . - GOC:tfm - ISBN:0323052908 - @@ -4202,39 +1597,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast). - CL:0000191 - BTO:0004576 - CALOHA:TS-2159 - FMA:14072 - SMCs - myocytes, smooth muscle - smooth muscle fiber - non-striated muscle cell - cell - smooth muscle cell - - - - - A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast). - MESH:A11.620.520 - MESH:D032389 - PMID:9315361 - http://en.wikipedia.org/wiki/Smooth_muscle_cell - - - - - SMCs - PMID:9315361 - - - - - myocytes, smooth muscle - MESH:D032389 - + @@ -4242,38 +1605,19 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A striated muscle cell of an arthropod heart that participates in heart contraction. - CL:0000466 - cell - cardiac muscle cell (sensu Arthopoda) - - - - A striated muscle cell of an arthropod heart that participates in heart contraction. - MESH:A11.620.500 - - - cell - Consider CL:0002072. - obsolete nodal cardiac cell - true - + - - cell - obsolete Purkinje fiber - true - + @@ -4281,8 +1625,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - flight muscle cell @@ -4291,8 +1633,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - receptor cell @@ -4301,19 +1641,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - The peripheral receptor for pain. Includes receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli. All mammalian nociceptors are free nerve endings. - nociceptor - nocireceptor - cell - Editor note: request detection of stimulus involved in sensory perception of pain; add develops_from relationship - pain receptor cell - - - - The peripheral receptor for pain. Includes receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli. All mammalian nociceptors are free nerve endings. - MESH:A08.800.550.700.650 - @@ -4321,23 +1649,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell specialized to transduce mechanical stimuli and relay that information centrally in the nervous system. - cell - mechanoreceptor - mechanoreceptor cell - - - - - A cell specialized to transduce mechanical stimuli and relay that information centrally in the nervous system. - MESH:A08.800.550.700.500 - - - - - mechanoreceptor - MP:0000972 - + @@ -4345,8 +1657,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - touch receptor cell @@ -4358,35 +1668,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A mechanoreceptor cell located in the inner ear that is sensitive to auditory stimuli. The accessory sensory structures are arranged so that appropriate stimuli cause movement of the hair-like projections (stereocilia and kinocilia) which relay the information centrally in the nervous system. - CL:0000201 - FMA:62364 - auditory receptor cell - cochlear hair cell - cell - inner ear hair cell - inner ear receptor cell - In mammals these cells are located in the organ of Corti. - auditory hair cell - - - - - A mechanoreceptor cell located in the inner ear that is sensitive to auditory stimuli. The accessory sensory structures are arranged so that appropriate stimuli cause movement of the hair-like projections (stereocilia and kinocilia) which relay the information centrally in the nervous system. - MESH:A08.663.650.250 - - - - - inner ear hair cell - GO:0060119 - - - - - inner ear receptor cell - GO:0060119 - + @@ -4395,8 +1677,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - gravity sensitive cell @@ -4405,8 +1685,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - acceleration receptive cell @@ -4415,18 +1693,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cellular receptor which mediates the sense of temperature. Thermoreceptor cells in vertebrates are mostly located under the skin. In mammals there are separate types of thermoreceptors for cold and for warmth and pain receptor cells which detect cold or heat extreme enough to cause pain. - cell - thermoreceptor cell - - - - A cellular receptor which mediates the sense of temperature. Thermoreceptor cells in vertebrates are mostly located under the skin. In mammals there are separate types of thermoreceptors for cold and for warmth and pain receptor cells which detect cold or heat extreme enough to cause pain. - GOC:tfm - MESH:A08.800.550.700.840 - MP:0000971 - @@ -4434,16 +1701,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell specialized to detect chemical substances and relay that information centrally in the nervous system. Chemoreceptors may monitor external stimuli, as in taste and olfaction, or internal stimuli, such as the concentrations of oxygen and carbon dioxide in the blood. - cell - chemoreceptor cell - - - - A cell specialized to detect chemical substances and relay that information centrally in the nervous system. Chemoreceptors may monitor external stimuli, as in taste and olfaction, or internal stimuli, such as the concentrations of oxygen and carbon dioxide in the blood. - MESH:A08.800.550.700.120 - @@ -4451,15 +1709,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - BTO:0004185 - FMA:67860 - Wikipedia:Olfactory_receptor_neuron - Schultze's cell - odorant receptor cell - olfactory receptor neuron - olfactory sensory neuron - cell - olfactory receptor cell @@ -4468,8 +1717,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - pH receptor cell @@ -4483,19 +1730,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell type found in the spherical or ovoid clusters of receptor cells found mainly in the epithelium of the tongue and constituting the end organs of the sense of taste. - FMA:67910 - taste bud cell - cell - taste receptor cell - - - - A cell type found in the spherical or ovoid clusters of receptor cells found mainly in the epithelium of the tongue and constituting the end organs of the sense of taste. - GOC:tfm - ISBN:0618947256 - @@ -4503,20 +1738,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell specialized to detect and transduce light. - BTO:0001060 - CALOHA:TS-0868 - FBbt:00004211 - FMA:86740 - cell - photoreceptor cell - - - - A cell specialized to detect and transduce light. - MESH:A08.663.650.650 - @@ -4524,16 +1746,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell whose function is determined by the generation or the reception of an electric signal. - cell - electrically active cell - - - - A cell whose function is determined by the generation or the reception of an electric signal. - FB:ma - @@ -4541,16 +1754,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell that takes up and metabolizes substances. - cell - absorptive cell - - - - A cell that takes up and metabolizes substances. - CL:CVS - @@ -4558,17 +1762,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell within an epithelial cell sheet whose main function is to act as an internal or external covering for a tissue or an organism. - boundary cell - cell - lining cell - - - - A cell within an epithelial cell sheet whose main function is to act as an internal or external covering for a tissue or an organism. - JB:jb - @@ -4578,23 +1772,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A meso-epithelial cell that lies between the cartilaginous fibers in the synovial membrane of a joint and produces hyaluronic acid. - BTO:0003652 - CALOHA:TS-0995 - FMA:66786 - synoviocyte - hyaluronic acid secreting cell - cell - synovial cell - - - - - A meso-epithelial cell that lies between the cartilaginous fibers in the synovial membrane of a joint and produces hyaluronic acid. - GOC:tfm - ISBN:0721662544 - PMID:17942474 - + @@ -4602,16 +1780,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell whose primary function is to prevent the transport of stuff across compartments. - cell - barrier cell - - - - A cell whose primary function is to prevent the transport of stuff across compartments. - JB:jb - @@ -4621,20 +1790,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A supporting cell projecting inward from the basement membrane of seminiferous tubules. They surround and nourish the developing male germ cells and secrete androgen binding protein. Their tight junctions with the spermatogonia and spermatocytes provide a blood-testis barrier. - BTO:0001238 - CALOHA:TS-0922 - FMA:72298 - VHOG:0001348 - cell - Sertoli cell - - - - A supporting cell projecting inward from the basement membrane of seminiferous tubules. They surround and nourish the developing male germ cells and secrete androgen binding protein. Their tight junctions with the spermatogonia and spermatocytes provide a blood-testis barrier. - MESH:A05.360.444.849.789 - @@ -4642,8 +1798,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - insulating cell @@ -4654,23 +1808,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A neuroglial cell of the peripheral nervous system which forms the insulating myelin sheaths of peripheral axons. - Schwann cell - peripheral neuroglial cell - CALOHA:TS-0898 - FMA:62121 - neurilemmal cell - cell - myelinating Schwann cell - - - - - A neuroglial cell of the peripheral nervous system which forms the insulating myelin sheaths of peripheral axons. - GOC:cvs - GOC:tfm - MESH:A08.637.800 - + @@ -4678,30 +1816,13 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell that moves by its own activities. - cell - motile cell - - - - A cell that moves by its own activities. - FB:ma - - - CL:0000000 - CL:0000003 - CL:0001034 - cell - This term was made obsolete because there is no difference in meaning between it and 'cell', as any cell in a multicellular organiam, apart from a zygote, can potentially be classified by its lineage. If you have used this term in annotation, please replace it with cell (CL:0000000), native cell (CL:0000003), or cell in vitro (CL:0001034) as appropriate. - obsolete cell by lineage - true - + @@ -4709,18 +1830,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell of the outer of the three germ layers of the embryo. - FMA:72549 - ectoderm cell - cell - ectodermal cell - - - - A cell of the outer of the three germ layers of the embryo. - MESH:A16.254.425.273 - @@ -4728,19 +1838,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell of the middle germ layer of the embryo. - FMA:72554 - mesoblast - mesoderm cell - cell - mesodermal cell - - - - A cell of the middle germ layer of the embryo. - MESH:A16.254.425.660 - @@ -4748,40 +1846,13 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell of the inner of the three germ layers of the embryo. - FMA:72555 - endoderm cell - cell - endodermal cell - - - - A cell of the inner of the three germ layers of the embryo. - MESH:A16.254.425.407 - - - OBSOLETE: A classification of cells by the number of their nuclei. - CL:0000000 - CL:0000003 - CL:0001034 - cell - This term was made obsolete because there is no difference in meaning between it and 'cell', as any cell can be classified by its nuclear number (note that this term was previously used as a parent class of enucleate cell). If you have used this term in annotation, please replace it with cell (CL:0000000), native cell (CL:0000003), or cell in vitro (CL:0001034) as appropriate. - obsolete cell by nuclear number - true - - - - - OBSOLETE: A classification of cells by the number of their nuclei. - FB:ma - GOC:tfm - + @@ -4789,36 +1860,16 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell that lacks a nucleus. - FMA:68647 - non-nucleated cell - cell - anucleate cell + - - - - A cell that lacks a nucleus. - FB:ma - - - A cell with a single nucleus. - cell - single nucleate cell + - - - - A cell with a single nucleus. - FB:ma - GOC:tfm - @@ -4826,8 +1877,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - binucleate cell @@ -4835,58 +1884,26 @@ Covers cells actively being cultured or stored in a quiescent state for future u - - A cell with more than one nucleus. - AEO:0000203 - WBbt:0008074 - syncitium - syncytial cell - syncytium - cell - multinucleate cell + - - - - A cell with more than one nucleus. - FB:ma - - - OBSOLETE (was not defined before being made obsolete). - cell - Refers to an activated mature lymphocyte phenotype rather than a distinct cell type; consider using 'lymphocyte ; CL:0000542' or one of its children instead. - obsolete lymphoblast - true - + - - OBSOLETE (was not defined before being made obsolete). - cell - Refers to an activated mature T lymphocyte phenotype rather than a distinct cell type; consider using 'T cell ; CL:0000084' or one of its children instead. - obsolete T lymphoblast - true - + - - OBSOLETE (was not defined before being made obsolete). - cell - Refers to an activated mature B lymphocyte phenotype rather than a distinct cell type; consider using 'B cell ; CL:0000236' or one of its children instead. - obsolete B lymphoblast - true - + @@ -4896,22 +1913,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen. - BTO:0000424 - CALOHA:TS-0290 - FMA:81100 - RBC - red blood cell - cell - erythrocyte - - - - A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen. - GOC:tfm - MESH:A11.118.290 - @@ -4922,33 +1924,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation. - BTO:0000132 - CALOHA:TS-0803 - FMA:62851 - anucleate thrombocyte - blood platelet - enucleate thrombocyte - cell - Platelets are reportedly CCR1-positive, CCR2-negative, CCR3-positive, CCR4-positive, CCR5-negative, CCR6-negative, CCR7-negative, CCR8-negative, CCR9-negative, CCR10-negative, CD16-positive, CD23-positive, CD32-positive, CD40-positive, CD41-positive CD42-positive, CD61-positive, CD62P-positive, CD64-positive, CD89-positive, CD102-positive, CD147-positive (activated platelets), CD154-positive (activated platelets), CD162-positive, CD209, CD282-positive, CD284-positive, CD289-positive, CD181-negative, CD182-negative, CD183-negative, CD184-positive, CLEC2-positive, GPVI-positive, JAMC-positive, PAR1-positive, PAR2-negative, PAR3-positive, PAR4-positive, TSP1-positive, and TXA2R-positive. Platelets can reportedly produce CCL2, CCL3, CCL5, CCL7, CCL17, CD40L, CXCL1, CXCL4, CXCL4L1, CXCL5, CXCL7, CXCL8, CXCL12, EGF, factor V, factor VII, factor XI, factor XIII, bFGF, histamine, IGF-1, IL-1beta, PAI-1, PDGF, plasminogen, protein S, serotonin, TGF-beta, TFPI, VEGF, and vWF. - platelet - - - - - A non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation. - GOC:add - GOC:dsd - GOC:tfm - MESH:A11.118.188 - MESH:D001792 - PMID:11110672 - PMID:16987572 - PMID:17204662 - PMID:17479180 - PMID:20414831 - http://en.wikipedia.org/wiki/Platelet - + @@ -4958,19 +1934,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Any cell capable of ingesting particulate matter via phagocytosis. - BTO:0001044 - FMA:83806 - cell - phagocyte - - - - Any cell capable of ingesting particulate matter via phagocytosis. - GOC:add - ISBN:0721601464 - @@ -4979,26 +1943,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells. - BTO:0000801 - CALOHA:TS-0587 - FMA:63261 - FMA:83585 - histiocyte - cell - Morphology: Diameter 30_M-80 _M, abundant cytoplasm, low N/C ratio, eccentric nucleus. Irregular shape with pseudopods, highly adhesive. Contain vacuoles and phagosomes, may contain azurophilic granules; markers: Mouse & Human: CD68, in most cases CD11b. Mouse: in most cases F4/80+; role or process: immune, antigen presentation, & tissue remodelling; lineage: hematopoietic, myeloid. - macrophage - - - - - A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells. - GOC:add - GOC:tfm - GO_REF:0000031 - PMID:16213494 - PMID:1919437 - + @@ -5006,26 +1951,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A lymphocyte of B lineage with the phenotype CD19-positive, CD20-positive, and capable of B cell mediated immunity. - BTO:0000776 - CALOHA:TS-0068 - FMA:62869 - VHOG:0001480 - B lymphocyte - B-cell - B-lymphocyte - cell - B cell - - - - - A lymphocyte of B lineage with the phenotype CD19-positive, CD20-positive, and capable of B cell mediated immunity. - GOC:add - GOC:tfm - GO_REF:0000031 - ISBN:0781735149 - + @@ -5035,8 +1961,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - keratinizing barrier epithelial cell @@ -5045,8 +1969,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - non keratinizing barrier epithelial cell @@ -5055,8 +1977,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - brush border epithelial cell @@ -5066,8 +1986,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - stratified squamous epithelial cell @@ -5076,8 +1994,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - stratified cuboidal epithelial cell @@ -5088,18 +2004,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A modified epidermal cell located in the stratum basale. They are found mostly in areas where sensory perception is acute. Merkel cells are closely associated with an expanded terminal bulb of an afferent myelinated nerve fiber. - FMA:70548 - Merkel's cell - cell - Merkel cell - - - - A modified epidermal cell located in the stratum basale. They are found mostly in areas where sensory perception is acute. Merkel cells are closely associated with an expanded terminal bulb of an afferent myelinated nerve fiber. - MESH:A08.800.550.700.500.425 - @@ -5107,16 +2012,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Form the myelin insulation of nervous pathways, guide neuronal migration during development, and exchange metabolites with neurons. Neuroglia have high-affinity transmitter uptake systems, voltage-dependent and transmitter-gated ion channels, and can release transmitters, but their role in signaling (as in many other functions) is unclear. - cell - glial cell (sensu Vertebrata) - - - - A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Form the myelin insulation of nervous pathways, guide neuronal migration during development, and exchange metabolites with neurons. Neuroglia have high-affinity transmitter uptake systems, voltage-dependent and transmitter-gated ion channels, and can release transmitters, but their role in signaling (as in many other functions) is unclear. - MESH:A08.637 - @@ -5125,36 +2021,13 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell characteristically found lining hollow organs that are subject to great mechanical change due to contraction and distention; originally thought to represent a transition between stratified squamous and columnar epithelium. - FMA:66778 - cell - transitional epithelial cell - - - - A cell characteristically found lining hollow organs that are subject to great mechanical change due to contraction and distention; originally thought to represent a transition between stratified squamous and columnar epithelium. - GOC:tfm - ISBN:0721662544 - - - Obsolete. Use PO:0000353 from Plant Ontology instead. Cell in exodermis or endodermis that remains thin walled when the associated cells develop thick secondary walls. Has casparian strip in endodermis. - cell - replaced_by: PO:0000353 - obsolete passage cell - true - - - - - Obsolete. Use PO:0000353 from Plant Ontology instead. Cell in exodermis or endodermis that remains thin walled when the associated cells develop thick secondary walls. Has casparian strip in endodermis. - ISBN:0471245208 - + @@ -5162,8 +2035,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - Mauthner neuron @@ -5172,54 +2043,13 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Type of neuron that is a primary mechanosensory cell, with peripheral neurites innervating the skin with free nerve endings. - AAO:0010316 - EFO:0003711 - VHOG:0001484 - Rohon Beard cell - Rohon-Beard cell - cell - RB neuron - Rohon-Beard neuron - - - - - Type of neuron that is a primary mechanosensory cell, with peripheral neurites innervating the skin with free nerve endings. - VHOG:0001484 - - - - - Rohon Beard cell - VHOG:0001484 - - - - - RB neuron - VHOG:0001484 - + - - Obsolete. Use PO:0020047 from Plant Ontology instead. A diploid (2n) cell that undergoes meiosis and forms four haploid (1n) microspores; also called microspore mother cell and, in seed plants, pollen mother cell. - pollen mother cell - primary sporogenous cell - cell - replaced_by: PO:0020047 - obsolete microsporocyte - true - - - - - Obsolete. Use PO:0020047 from Plant Ontology instead. A diploid (2n) cell that undergoes meiosis and forms four haploid (1n) microspores; also called microspore mother cell and, in seed plants, pollen mother cell. - ISBN:0471245208 - + @@ -5227,27 +2057,13 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - hatching gland cell - - Obsolete. Use PO:0020019 from Plant Ontology instead. A haploid (1n) spore developing into a female gametophyte in heterosporous plants. - cell - replaced_by: PO:0020019 - obsolete megaspore - true - - - - - Obsolete. Use PO:0020019 from Plant Ontology instead. A haploid (1n) spore developing into a female gametophyte in heterosporous plants. - ISBN:0471245208 - + @@ -5255,27 +2071,13 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - extramedullary cell - - Obsolete. Use PO:0020048 from Plant Ontology instead. A haploid (1n) spore developing into a male gametophyte in heterosporous plants; the uninucleate pollen grain in seed plants. - cell - replaced_by: PO:0020048 - obsolete microspore - true - - - - - Obsolete. Use PO:0020048 from Plant Ontology instead. A haploid (1n) spore developing into a male gametophyte in heterosporous plants; the uninucleate pollen grain in seed plants. - ISBN:0471245208 - + @@ -5283,28 +2085,13 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - eurydendroid cell - - Obsolete. Use PO:0020094 from Plant Ontology instead. The female gamete of plants. - female gametophyte egg cell - cell - replaced_by: PO:0020094 - obsolete egg cell - true - - - - - Obsolete. Use PO:0020094 from Plant Ontology instead. The female gamete of plants. - TAIR:lr - + @@ -5312,8 +2099,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - eukaryotic cell + @@ -5322,8 +2108,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - uric acid accumulating cell @@ -5332,392 +2116,169 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - Mycetozoan cell - - Obsolete. Use PO:0000355 from Plant Ontology instead. A fiber like tracheid in the secondary xylem; commonly thick walled, with pointed ends and bordered pits that have lenticular to slit like apertures. - cell - replaced_by: PO:0000355 - obsolete fiber tracheid - true - - - - - Obsolete. Use PO:0000355 from Plant Ontology instead. A fiber like tracheid in the secondary xylem; commonly thick walled, with pointed ends and bordered pits that have lenticular to slit like apertures. - ISBN:0471245208 - + - - DDANAT:0000403 - obsolete aggregate cell - true - + - - Obsolete. Use PO:0000373 from Plant Ontology instead. Cell containing mucilages or gums or similar carbohydrate material characterized by the property of swelling in water. - cell - replaced_by: PO:0000373 - obsolete mucilage cell - true - - - - - Obsolete. Use PO:0000373 from Plant Ontology instead. Cell containing mucilages or gums or similar carbohydrate material characterized by the property of swelling in water. - ISBN:0471245208 - + - - cell - anterior cell - + - - Obsolete. Use PO:0000351 from Plant Ontology instead. An epidermal cell that divides to produce the guard cells. - cell - replaced_by: PO:0000351 - obsolete guard mother cell - true - - - - - Obsolete. Use PO:0000351 from Plant Ontology instead. An epidermal cell that divides to produce the guard cells. - ISBN:0471245208 - + - - DDANAT:0000002 - obsolete vegetative cell (sensu Mycetozoa) - true - + - - Obsolete. Use PO:0000400 from Plant Ontology instead. A cambial cell on the phloem side of the cambial zone that is the source of one or more cells arising by periclinal divisions and differentiating into phloem elements with or without additional divisions in various planes. - phloem mother cell - cell - replaced_by: PO:0000400 - obsolete phloem initial - true - - - - - Obsolete. Use PO:0000400 from Plant Ontology instead. A cambial cell on the phloem side of the cambial zone that is the source of one or more cells arising by periclinal divisions and differentiating into phloem elements with or without additional divisions in various planes. - ISBN:0471245208 - + - - DDANAT:0000404 - obsolete anterior like cell - true - + - - Obsolete. Use PO:0004011 from Plant Ontology instead. A cell constituting an active locus of meristematic activity in a tissue composed of somewhat older, differentiating cells. - cell - replaced_by: PO:0004011 - obsolete meristemoid - true - - - - - Obsolete. Use PO:0004011 from Plant Ontology instead. A cell constituting an active locus of meristematic activity in a tissue composed of somewhat older, differentiating cells. - ISBN:0471245208 - + - - DDANAT:0000405 - obsolete prespore cell - true - + - - Obsolete. Consult Plant Ontology instead. The cell in the phloem tissue concerned with mainly longitudinal conduction of food materials. Classified into sieve cell and sieve tube member. - cell - obsolete sieve element - true - - - - - Obsolete. Consult Plant Ontology instead. The cell in the phloem tissue concerned with mainly longitudinal conduction of food materials. Classified into sieve cell and sieve tube member. - ISBN:0471245208 - + - - DDANAT:0000406 - obsolete prestalk cell - true - + - - Obsolete. Use PO:0000284 from Plant Ontology instead. An epidermal cell associated with a stoma and at least morphologically distinguishable from the epidermal cells composing the groundmass of the tissue. - cell - replaced_by: PO:0000284 - obsolete subsidiary cell - true - - - - - Obsolete. Use PO:0000284 from Plant Ontology instead. An epidermal cell associated with a stoma and at least morphologically distinguishable from the epidermal cells composing the groundmass of the tissue. - ISBN:047124520 - + - - DDANAT:0000408 - obsolete prestalk A cell - true - + - - OBSOLETE, use term from Plant Ontology. A cell localized in the vascular cambium or phellogen. Its periclinal division can contribute cells either to the outside or to the inside of the axis; in vascular cambium, classified into fusiform initials (source of axial cells of xylem and phloem) and ray initials (source of the ray cells). - cell - replaced_by PO:0000295 - obsolete cambial initial - true - - - - - OBSOLETE, use term from Plant Ontology. A cell localized in the vascular cambium or phellogen. Its periclinal division can contribute cells either to the outside or to the inside of the axis; in vascular cambium, classified into fusiform initials (source of axial cells of xylem and phloem) and ray initials (source of the ray cells). - ISBN:0471245208 - + - - DDANAT:0000410 - obsolete prestalk AB cell - true - + - - DDANAT:0000409 - obsolete prestalk B cell - true - + - - Obsolete. Use PO:0000077 from Plant Ontology instead. Cell variable in form and size, being more or less thick, often lignified, secondary walls. Belongs to the category of subcells and may or may not be devoid of protoplast at maturity. - cell - replaced_by: PO:0000077 - obsolete sclerenchyma cell - true - - - - - Obsolete. Use PO:0000077 from Plant Ontology instead. Cell variable in form and size, being more or less thick, often lignified, secondary walls. Belongs to the category of subcells and may or may not be devoid of protoplast at maturity. - ISBN:0471245208 - + - - OBSOLETE: Initial population of prestalk cells that activate the ecmA promoter at the mound stage and that presumably further differentiate into pstA and pstO cells. - DDANAT:0000406 - cell - This cell type does not exist in Dictyostelium. it has been long deleted in their anatomy ontology. - obsolete prestalk I cell - true - - - - - OBSOLETE: Initial population of prestalk cells that activate the ecmA promoter at the mound stage and that presumably further differentiate into pstA and pstO cells. - DictyBase:DDB - + - - Obsolete. Use PO:0020090 from Plant Ontology instead. OBSOLETED, use term from Plant Ontology. A cell containing the two polar nuclei which, after double fertilization, will develop into the endosperm. - cell - replaced_by: PO:0020090 - obsolete central cell - true - - - - - Obsolete. Use PO:0020090 from Plant Ontology instead. OBSOLETED, use term from Plant Ontology. A cell containing the two polar nuclei which, after double fertilization, will develop into the endosperm. - TAIR:lr - + - - DDANAT:0000407 - obsolete prestalk 0 cell - true - + - - Obsolete. Use PO:0020097 from Plant Ontology instead. The cell that will give rise to the generative nuclei which will participate in fertilization. - cell - replaced_by: PO:0020097 - obsolete generative cell - true - - - - - Obsolete. Use PO:0020097 from Plant Ontology instead. The cell that will give rise to the generative nuclei which will participate in fertilization. - TAIR:lr - + - - DDANAT:0000411 - obsolete pstAB/ALC - true - + - - Obsolete. Use PO:0000282 from Plant Ontology instead. An outgrowth from the epidermis. Trichomes vary in size and complexity and include hairs, scales, and other structures and may be glandular. In Arabidopsis, patterning of trichome development is not random but does not appear to be lineage-based like stomata. - cell - replaced_by: PO:0000282 - obsolete trichome - true - - - - - Obsolete. Use PO:0000282 from Plant Ontology instead. An outgrowth from the epidermis. Trichomes vary in size and complexity and include hairs, scales, and other structures and may be glandular. In Arabidopsis, patterning of trichome development is not random but does not appear to be lineage-based like stomata. - ISBN:0471245208 - PMID:10938806 - + - - DDANAT:0000412 - obsolete pstO/ALC - true - + - - Obsolete. Use PO:0000071 from Plant Ontology instead. A specialized parenchyma cell associated with a sieve-tube member in angiosperm phloem and arising from the same mother cell as the sieve-tube member. - cell - replaced_by: PO:0000071 - obsolete companion cell - true - - - - - Obsolete. Use PO:0000071 from Plant Ontology instead. A specialized parenchyma cell associated with a sieve-tube member in angiosperm phloem and arising from the same mother cell as the sieve-tube member. - ISBN:0879015322 - + - - DDANAT:0000413 - obsolete stalk cell - true - + @@ -5725,16 +2286,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell of a filament of a fungal mycelium. - cell - hyphal cell - - - - A cell of a filament of a fungal mycelium. - ISBN:08199377X - @@ -5742,84 +2294,37 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - eye photoreceptor cell - - Obsolete. Use PO:0000191 from Plant Ontology instead. A cell in the micropylar end of the embryo sac associated with the egg in the egg apparatus of angiosperms. Plays a vital role in fertilization. - cell - replaced_by: PO:0000191 - obsolete synergid - true - - - - - Obsolete. Use PO:0000191 from Plant Ontology instead. A cell in the micropylar end of the embryo sac associated with the egg in the egg apparatus of angiosperms. Plays a vital role in fertilization. - ISBN:047125208 - + - - DDANAT:0000402 - obsolete chemotactic amoeboid cell (sensu Mycetozoa) - true - + - - Obsolete. Use PO:0000274 from Plant Ontology instead. A fiber of the xylem tissue, Two types are recognized in the secondary xylem: fiber tracheids and libriform fibers. - cell - replaced_by: PO:0000274 - obsolete xylem fiber cell - true - - - - - Obsolete. Use PO:0000274 from Plant Ontology instead. A fiber of the xylem tissue, Two types are recognized in the secondary xylem: fiber tracheids and libriform fibers. - ISBN:0471245208 - + - - DDANAT:0000414 - obsolete spore (sensu Mycetozoa) - true - + - - Obsolete. Use PO:0000293 from Plant Ontology instead. One of a pair of cells flanking the stomatal pore and causing the opening and closing of the pore by changes in turgor. - stomatal guard cell - cell - replaced_by: PO:0000293 - obsolete guard cell - true - - - - - Obsolete. Use PO:0000293 from Plant Ontology instead. One of a pair of cells flanking the stomatal pore and causing the opening and closing of the pore by changes in turgor. - ISBN:0471245208 - + @@ -5827,33 +2332,13 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell whose primary function is to provide structural support, to provide strength and physical integrity to the organism. - cell - structural cell - - - - A cell whose primary function is to provide structural support, to provide strength and physical integrity to the organism. - TAIR:sr - - - Obsolete. Consult Plant Ontology instead. A type of sieve element that has relatively undifferentiated sieve areas (with narrow pores), rather uniform in structure on all walls; that is, there are no sieve plates. Typical of gymnosperms and lower vascular plants. - cell - obsolete sieve cell - true - - - - - Obsolete. Consult Plant Ontology instead. A type of sieve element that has relatively undifferentiated sieve areas (with narrow pores), rather uniform in structure on all walls; that is, there are no sieve plates. Typical of gymnosperms and lower vascular plants. - ISBN:0471245208 - + @@ -5861,93 +2346,31 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A peptide hormone secreting cell that produces growth hormone, somatotropin. - CL:0000471 - growth hormone secreting cell - somatotrophin secreting cell - cell - somatotropin secreting cell - - - - A peptide hormone secreting cell that produces growth hormone, somatotropin. - GOC:tfm - SANBI:mhl - - - Obsolete. Use PO:0020099 from Plant Ontology instead. Cell type formed after the first mitotic division of the microgametophye, The nucleus of this cell migrates to the tip of the pollen tube after germination and disintegrates when the pollen tube penetrates the nucellus. - cell - replaced_by: PO:0020099 - obsolete vegetative cell - true - - - - - Obsolete. Use PO:0020099 from Plant Ontology instead. Cell type formed after the first mitotic division of the microgametophye, The nucleus of this cell migrates to the tip of the pollen tube after germination and disintegrates when the pollen tube penetrates the nucellus. - ISBN:0140514031 - TAIR:lr - + - - Obsolete. Use PO:0000115 from Plant Ontology instead. A cell that surrounds a trichome and provides support for the trichome. - cell - replaced_by: PO:0000115 - obsolete socket cell - true - - - - - Obsolete. Use PO:0000115 from Plant Ontology instead. A cell that surrounds a trichome and provides support for the trichome. - PMID:10938806 - + - - Obsolete. Use PO:0000273 from Plant Ontology instead. A cell composing the xylem. - cell - replaced_by: PO:0000273 - obsolete xylem element - true - - - - - Obsolete. Use PO:0000273 from Plant Ontology instead. A cell composing the xylem. - ISBN:0471245208 - + - - OBSOLETED. Commonly used for a cell in root epidermis that gives rise to a root hair. The daughter cell produced by the asymmetric division of a root epidermal cell that gives rise to a root hair. - cell - Obsoleted. Use trichoblast from the plant ontology (PO:0000262). - obsolete trichoblast - true - - - - - OBSOLETED. Commonly used for a cell in root epidermis that gives rise to a root hair. The daughter cell produced by the asymmetric division of a root epidermal cell that gives rise to a root hair. - ISBN:0471245208 - + @@ -5956,22 +2379,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A mature sexual reproductive cell having a single set of unpaired chromosomes. - CALOHA:TS-0395 - FBbt:00005412 - FMA:18649 - haploid nucleated cell - cell - haploid germ cell - gamete - - - - A mature sexual reproductive cell having a single set of unpaired chromosomes. - GOC:tfm - ISBN:0721662544 - @@ -5979,58 +2387,31 @@ Covers cells actively being cultured or stored in a quiescent state for future u - FBbt:00000092 - cell - pole cell - - OBSOLETE (was not defined before being made obsolete). - cell - Not a differentiation state per se; consider using 'B cell ; CL:0000236' or one of its children instead. - obsolete IgM B cell - true - + - - OBSOLETE (was not defined before being made obsolete). - cell - Not a differentiation state per se, and IgG isotypes vary by species; consider using 'B cell ; CL:0000236' or one of its children instead. - obsolete IgG B cell - true - + - - OBSOLETE (was not defined before being made obsolete). - cell - Not a differentiation state per se, and IgA isotypes vary by species. Consider using 'B cell ; CL:0000236' or one of its children instead. - obsolete IgA B cell - true - + - - OBSOLETE (was not defined before being made obsolete). - cell - Not a differentiation state per se; consider using 'B cell ; CL:0000236' or one of its children instead. - obsolete IgE B cell - true - + @@ -6038,10 +2419,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - FBbt:00004193 - lens cell - cell - crystallin accumulating cell @@ -6050,20 +2427,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An epithelial cell found in the trachea. - CL:1000474 - FMA:74793 - tracheocyte - cell - This class is for the vertebrate tracheal structure. For the analagous insect cell type, see 'respiratory tube epithelial cell' - tracheal epithelial cell - - - - An epithelial cell found in the trachea. - GOC:tfm - @@ -6071,8 +2435,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - metal ion accumulating cell @@ -6081,9 +2443,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cuprophilic cell - cell - copper accumulating cell @@ -6092,8 +2451,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - iron accumulating cell @@ -6102,8 +2459,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - keratin accumulating cell @@ -6113,29 +2468,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell. - CL:0002185 - BTO:0000667 - CALOHA:TS-0500 - FMA:62879 - keratinized cell of epidermis - malpighian cell - cell - Keratinocytes are reportedly CDw210a-negative, CDw210b-positive, CD281-positive, CD282-positive, CD285-positive, IL22Ra1-positive, Human keratinocytes are reportedly capable of secreting BD-2, BD-3, hCAP-18, CXCL1, CXCL5, CXCL8, elafin, MMP-3, NGAL, PDGF-A, S100A7, S100A8, and S100A9. Transcription factors: STAT3-positive. - keratinocyte - - - - - An epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell. - GOC:dsd - MESH:A11.436.397 - MESH:D015603 - PMID:15582983 - PMID:15749908 - PMID:19727116 - http://en.wikipedia.org/wiki/Keratinocyte - + @@ -6143,21 +2476,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Columnar glandular cell with irregular nucleus, copious granular endoplasmic reticulum and supranuclear granules. Secretes a watery fluid containing proteins known as serous fluid. - BTO:0003687 - FMA:62511 - serous cell - cell - serous secreting cell - - - - Columnar glandular cell with irregular nucleus, copious granular endoplasmic reticulum and supranuclear granules. Secretes a watery fluid containing proteins known as serous fluid. - GOC:tfm - ISBN:0517223651 - ISBN:0721662544 - @@ -6165,8 +2484,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - milk secreting cell @@ -6175,34 +2492,13 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell secreting tears, the fluid secreted by the lacrimal glands. This fluid moistens the conjunctiva and cornea. - cell - tears secreting cell - - - - A cell secreting tears, the fluid secreted by the lacrimal glands. This fluid moistens the conjunctiva and cornea. - MESH:A12.200.882 - - - Obsolete. Use PO:0000082 from Plant Ontology instead. A meristemic ray cell in the vascular cambium that gives rise to ray cells of the secondary xylem and secondary phloem. - cell - replaced_by: PO:0000082 - obsolete ray initial - true - - - - - Obsolete. Use PO:0000082 from Plant Ontology instead. A meristemic ray cell in the vascular cambium that gives rise to ray cells of the secondary xylem and secondary phloem. - ISBN:0471245208 - + @@ -6211,17 +2507,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell secreting sebun, an oily substance secreted by sebaceous glands, composed of keratin, fat, and cellular debris. - sebocyte - cell - sebum secreting cell - - - - A cell secreting sebun, an oily substance secreted by sebaceous glands, composed of keratin, fat, and cellular debris. - MESH:A12.200.702 - @@ -6229,16 +2515,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell secreting sweat, the fluid excreted by the sweat glands of mammals. It consists of water containing sodium chloride, phosphate, urea, ammonia, and other waste products. - cell - sweat secreting cell - - - - A cell secreting sweat, the fluid excreted by the sweat glands of mammals. It consists of water containing sodium chloride, phosphate, urea, ammonia, and other waste products. - MESH:A12.200.849 - @@ -6246,31 +2523,13 @@ Covers cells actively being cultured or stored in a quiescent state for future u - BTO:0003689 - mucous cell - cell - mucus secreting cell - - Obsolete. Use PO:0000431 from Plant Ontology instead. A diploid (2n) cell that undergoes meiosis and produces four haploid (1n) megaspores; also called megaspore mother cell. - archesporial cell - megaspore mother cell - cell - replaced_by: PO:0000431 - obsolete megasporocyte - true - - - - - Obsolete. Use PO:0000431 from Plant Ontology instead. A diploid (2n) cell that undergoes meiosis and produces four haploid (1n) megaspores; also called megaspore mother cell. - ISBN:0471245208 - + @@ -6278,8 +2537,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - seminal fluid secreting cell @@ -6288,22 +2545,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An epithelial cell that lines the peripheral gas exchange region of the lungs of air-breathing vertebrates. - BTO:0000395 - CALOHA:TS-2168 - FMA:62499 - alveolar epithelial cell - pneumonocyte - cell - pneumocyte - - - - An epithelial cell that lines the peripheral gas exchange region of the lungs of air-breathing vertebrates. - GOC:tfm - PMID:20054144 - @@ -6311,8 +2553,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - lysozyme secreting cell @@ -6321,8 +2561,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - metanephric mesenchyme stem cell @@ -6331,17 +2569,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell that is specialised to accumulate a particular substance(s). - cell - - stuff accumulating cell - - - - A cell that is specialised to accumulate a particular substance(s). - FB:ma - @@ -6349,8 +2577,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - glycogen accumulating cell @@ -6360,8 +2586,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - extracellular matrix secreting cell @@ -6370,8 +2594,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - myelin accumulating cell @@ -6380,64 +2602,25 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - oxygen accumulating cell - - Obsolete. Use PO:0000075 from Plant Ontology instead. An elongated living cell with unevenly thickened nonlignified primary walls. - cell - replaced_by: PO:0000075 - obsolete collenchymal cell - true - - - - - Obsolete. Use PO:0000075 from Plant Ontology instead. An elongated living cell with unevenly thickened nonlignified primary walls. - ISBN:0471245208 - + - - Obsolete. Use PO:0000301 from Plant Ontology instead. A tracheary element of the xylem that has no perforations, as contrasted with a vessel member. May occur in primary and in secondary xylem. May have any kind of secondary wall thickening found in tracheary elements. - cell - replaced_by: PO:0000301 - obsolete tracheid - true - - - - - Obsolete. Use PO:0000301 from Plant Ontology instead. A tracheary element of the xylem that has no perforations, as contrasted with a vessel member. May occur in primary and in secondary xylem. May have any kind of secondary wall thickening found in tracheary elements. - ISBN:0471245208 - + - - OBSOLETE, use term from Plant Ontology. A cell formed after asymmetric division of root epidermal cell that does not give rise to a root hair. - cell - non-hair cell - replaced_by: PO:0020090 - obsolete atrichoblast - true - - - - - OBSOLETE, use term from Plant Ontology. A cell formed after asymmetric division of root epidermal cell that does not give rise to a root hair. - ISBN:0387987819 - + @@ -6446,17 +2629,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell derived from the specialized ectoderm flanking each side of the embryonic neural plate, which after the closure of the neural tube, forms masses of cells that migrate out from the dorsal aspect of the neural tube to spread throughout the body. - FMA:86667 - cell - migratory neural crest cell - - - - A cell derived from the specialized ectoderm flanking each side of the embryonic neural plate, which after the closure of the neural tube, forms masses of cells that migrate out from the dorsal aspect of the neural tube to spread throughout the body. - MESH:A16.254.600 - @@ -6464,11 +2637,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - BTO:0002307 - FAO:0000032 - cell - yeast-form - vegetative cell (sensu Fungi) @@ -6477,17 +2645,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A mesenchymal cell in embryonic development found in a contracting mass and that gives rise to osteoprogenitors. - cell - mesenchyme condensation cell - - - - A mesenchymal cell in embryonic development found in a contracting mass and that gives rise to osteoprogenitors. - GOC:tfm - PMID:5025404 - @@ -6496,26 +2654,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell found within the adrenal medulla that secrete biogenic amine hormones upon stimulation. - CL:1000422 - FMA:69262 - medullary chromaffin cell of adrenal gland - cell - adrenal medulla chromaffin cell - - - - - A cell found within the adrenal medulla that secrete biogenic amine hormones upon stimulation. - GOC:tfm - http://www.britannica.com/EBchecked/topic/6405/adrenal-gland - - - - - medullary chromaffin cell of adrenal gland - FMA:69262 - + @@ -6523,16 +2662,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An embryonic cell that develops into a nerve cell or neuron. - cell - neuroblast (sensu Vertebrata) - - - - An embryonic cell that develops into a nerve cell or neuron. - FMA:70563 - @@ -6540,9 +2670,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - neuroblast - cell - neuroblast (sensu Nematoda and Protostomia) @@ -6552,19 +2679,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An early neural cell developing from the early ependymal cell of the neural tube. - FMA:70564 - spongioblast - cell - glioblast (sensu Vertebrata) - - - - An early neural cell developing from the early ependymal cell of the neural tube. - GOC:tfm - ISBN:0618947256 - @@ -6573,8 +2688,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - glioblast (sensu Nematoda and Protostomia) @@ -6583,8 +2696,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - pigment cell (sensu Nematoda and Protostomia) @@ -6593,17 +2704,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Any animal cell containing pigment granules. - cell - pigment cell (sensu Vertebrata) - - - - Any animal cell containing pigment granules. - GOC:tfm - ISBN:0721662544 - @@ -6612,27 +2713,13 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A pigment cell that is capable of detecting light stimulus that is involved in visual perception. - FMA:63846 - cell - visual pigment cell (sensu Vertebrata) - - - - A pigment cell that is capable of detecting light stimulus that is involved in visual perception. - GOC:tfm - - - cell - obsolete non-visual cell (sensu Vertebrata) - true - + @@ -6640,18 +2727,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A mesenchymal cell that is part of a small mass of condensed mesenchyme in the enamel organ; it differentiates into the dentin and dental pulp. - cell - Merge with odontoblast? - dental papilla cell - - - - A mesenchymal cell that is part of a small mass of condensed mesenchyme in the enamel organ; it differentiates into the dentin and dental pulp. - GOC:tfm - ISBN:0721662544 - @@ -6659,18 +2735,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A specialized mesenchymal cell that resides in the dermal papilla located at the bottom of hair follicles. This cell plays a pivotal roles in hair formation, growth, and cycling. - cell - Are these really all stem cells? - hair follicle dermal papilla cell - - - - A specialized mesenchymal cell that resides in the dermal papilla located at the bottom of hair follicles. This cell plays a pivotal roles in hair formation, growth, and cycling. - GOC:tfm - PMID:9893172 - @@ -6678,16 +2743,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell of the sclera of the eye. - cell - scleral cell - - - - A cell of the sclera of the eye. - GOC:add - @@ -6695,16 +2751,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell of the choroid of the eye. - cell - choroidal cell of the eye - - - - A cell of the choroid of the eye. - GOC:add - @@ -6713,8 +2760,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - extraembryonic cell @@ -6724,8 +2769,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - amnioserosal cell @@ -6734,19 +2777,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell lining the outside of the blastocyst. After binding to the endometrium, trophoblast cells develop into two distinct layers, an inner layer of mononuclear cytotrophoblast cells and an outer layer of continuous multinuclear cytoplasm, the syncytiotrophoblast cells, which form the early fetal-maternal interface. - FMA:83028 - trophoblastic cell - cell - trophoblast cell - - - - A cell lining the outside of the blastocyst. After binding to the endometrium, trophoblast cells develop into two distinct layers, an inner layer of mononuclear cytotrophoblast cells and an outer layer of continuous multinuclear cytoplasm, the syncytiotrophoblast cells, which form the early fetal-maternal interface. - GOC:tfm - MESH:A11.936 - @@ -6754,17 +2785,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell of the outer layer of a blastula that gives rise to the ectoderm after gastrulation. - cell - epiblast cell - - - - A cell of the outer layer of a blastula that gives rise to the ectoderm after gastrulation. - GOC:tfm - ISBN:0618947256 - @@ -6772,19 +2793,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An undifferentiated cell produced by early cleavages of the fertilized egg (zygote). - BTO:0001473 - FMA:72551 - blastomere - cell - blastoderm cell - - - - An undifferentiated cell produced by early cleavages of the fertilized egg (zygote). - MESH:A11.104 - @@ -6792,10 +2801,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - ncithesaurus:Blastemal_Cell - blastema cell - cell - blastemal cell @@ -6805,18 +2810,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A multifate stem cell found in skeletal muscle than can differentiate into many different cell types, including muscle. Distinct cell type from satellite cell. - FMA:86767 - cell - Multi-potency demonstrated ex vivo. At the time of writing, it is unclear whether the endogenous population differentiates into multiple cell types in vivo. - multi-potent skeletal muscle stem cell - - - - A multifate stem cell found in skeletal muscle than can differentiate into many different cell types, including muscle. Distinct cell type from satellite cell. - PMID:18282570 - @@ -6824,8 +2818,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - hair matrix stem cell @@ -6834,8 +2826,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - stratified epithelial stem cell @@ -6844,16 +2834,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A smooth muscle cell that is part of a sphincter. A sphincter is a typically circular muscle that normally maintains constriction of a natural body passage or orifice and which relaxes as required by normal physiological functioning. - cell - sphincter associated smooth muscle cell - - - - A smooth muscle cell that is part of a sphincter. A sphincter is a typically circular muscle that normally maintains constriction of a natural body passage or orifice and which relaxes as required by normal physiological functioning. - GOC:cjm - @@ -6861,19 +2842,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A smooth muscle cell assocatiated with the vasculature. - VSMC - vascular smooth muscle cell - cell - vascular associated smooth muscle cell - - - - A smooth muscle cell assocatiated with the vasculature. - GOC:dsd - GOC:tfm - @@ -6881,16 +2850,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell of the early embryo at the developmental stage in which the blastomeres, resulting from repeated mitotic divisions of the fertilized ovum (zygote), form a compact cell mass. - cell - morula cell - - - - A cell of the early embryo at the developmental stage in which the blastomeres, resulting from repeated mitotic divisions of the fertilized ovum (zygote), form a compact cell mass. - MESH:A16.254.270.550 - @@ -6898,16 +2858,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell of the embryo in the early stage following the blastula, characterized by morphogenetic cell movements, cell differentiation, and the formation of the three germ layers. - cell - gastrula cell - - - - A cell of the embryo in the early stage following the blastula, characterized by morphogenetic cell movements, cell differentiation, and the formation of the three germ layers. - MESH:A16.254.412 - @@ -6915,70 +2866,19 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An epithelial cell of the integument (the outer layer of an organism). - CL:1000396 - BTO:0001470 - CALOHA:TS-0283 - FMA:62411 - cell of epidermis - epithelial cell of skin - cell - epidermal cell - - - - - An epithelial cell of the integument (the outer layer of an organism). - Flybase:dsj - MA:ma - - - - - cell of epidermis - FMA:62411 - - - - - epithelial cell of skin - FMA:62411 - + - - Obsolete. Use PO:0000081 from Plant Ontology instead. OBSOLETE, use term from the Plant Ontology. A secondary vascular cell that develops from the fusiform cambial initials and oriented with their longest diameter parallel with the main axis of stem or root. These cells make up the axial system, also known as vertical or longitudinal system. - cell - replaced_by: PO:0000081 - obsolete axial cell - true - - - - - Obsolete. Use PO:0000081 from Plant Ontology instead. OBSOLETE, use term from the Plant Ontology. A secondary vascular cell that develops from the fusiform cambial initials and oriented with their longest diameter parallel with the main axis of stem or root. These cells make up the axial system, also known as vertical or longitudinal system. - ISBN:0471245208 - + - - Obsolete. Consult Plant Ontology. A cell that develops from the ray initial and composes all rays (panels of tissue variable in height and width, formed by the ray initials in the vascular cambium and extending radially in the secondary xylem and secondary phloem) in the secondary vascular tissues. - cell - obsolete ray cell - true - - - - - Obsolete. Consult Plant Ontology. A cell that develops from the ray initial and composes all rays (panels of tissue variable in height and width, formed by the ray initials in the vascular cambium and extending radially in the secondary xylem and secondary phloem) in the secondary vascular tissues. - ISBN:0471245208 - + @@ -6986,41 +2886,13 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Diploid cell produced by the fusion of sperm cell nucleus and egg cell. - zygote - BTO:0000854 - EHDAA2:0004546 - FMA:72395 - cell - animal zygote - - - - Diploid cell produced by the fusion of sperm cell nucleus and egg cell. - ISBN:0471245208 - - - Obsolete. Use PO:0000084 from Plant Ontology instead. Male gamete, part of male germ unit. - cell - gametophyte sperm cell - male gametophyte sperm cell - pollen germ cell - replaced_by: PO:0000084 - obsolete sperm cell (sensu Viridiplantae) - true - - - - - Obsolete. Use PO:0000084 from Plant Ontology instead. Male gamete, part of male germ unit. - ISBN:0471245208 - + @@ -7028,47 +2900,19 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - glial cell (sensu Nematoda) - sheath cell (sensu Nematoda) - - Obsolete. Use PO:0000352 from Plant Ontology instead. Cell containing glucosinolates ('mustard oil glucosides') and myrosinases, enzymes hydrolyzing the glucosinolates. Occurs in eleven dicotyledon families, the two largest of which are the Brassicaceae and Euphorbiaceae. - cell - replaced_by: PO:0000352 - obsolete myrosin cell - true - - - - - Obsolete. Use PO:0000352 from Plant Ontology instead. Cell containing glucosinolates ('mustard oil glucosides') and myrosinases, enzymes hydrolyzing the glucosinolates. Occurs in eleven dicotyledon families, the two largest of which are the Brassicaceae and Euphorbiaceae. - ISBN:0471245208 - + - - Obsolete. Use PO:0000078 from Plant Ontology instead. Parenchyma cell with the wall ingrowth (or invaginations) that increase the surface of the plasmalemma. Appears to be specialized for short-distance transfer of solutes. - cell - intermediary cell - replaced_by: PO:0000078 - obsolete transfer cell - true - - - - - Obsolete. Use PO:0000078 from Plant Ontology instead. Parenchyma cell with the wall ingrowth (or invaginations) that increase the surface of the plasmalemma. Appears to be specialized for short-distance transfer of solutes. - ISBN:0471245208 - + @@ -7076,16 +2920,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - The cell protoplasm after removal of the cell wall. - cell - protoplast - - - - The cell protoplasm after removal of the cell wall. - ISBN:08199377X - @@ -7093,24 +2928,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An epidermal cell that is part of a cell cluster organ of the insect integument (such as a sensillum) and that secretes a cuticular specialization that forms a socket around the base of a cuticular specialization produced by a trichogen cell. - socket cell - FBbt:00005171 - cell - tormogen cell - - - - - An epidermal cell that is part of a cell cluster organ of the insect integument (such as a sensillum) and that secretes a cuticular specialization that forms a socket around the base of a cuticular specialization produced by a trichogen cell. - ISBN:978-0801481253 - - - - - socket cell - ISBN:978-0801481253 - + @@ -7118,9 +2936,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - FBbt:00001789 - cell - histoblast @@ -7129,31 +2944,13 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An epidermal cell that is part of a cell cluster organ of the insect integument (such as a sensillum) and that secretes a cuticular specialization, often in the form of a hair, bristle, peg or scale. The base of this specialization is often surrounded by a socket produced by a closely associated tormogen cell. - hair cell - BTO:0004744 - FBbt:00005169 - cell - trichogen cell - - - - An epidermal cell that is part of a cell cluster organ of the insect integument (such as a sensillum) and that secretes a cuticular specialization, often in the form of a hair, bristle, peg or scale. The base of this specialization is often surrounded by a socket produced by a closely associated tormogen cell. - ISBN:978-0801481253 - - - CL:0007010 - BTO:0002051 - cell - obsolete osteoprogenitor cell - true - + @@ -7161,8 +2958,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - humidity receptor cell @@ -7171,8 +2966,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - tracheoblast @@ -7181,8 +2974,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - support cell (sensu Nematoda and Protostomia) @@ -7191,8 +2982,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - sensory processing neuron @@ -7201,17 +2990,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - The support cell that makes the thecogen dendritic cap - a cuticle-like matrix around the tip of the eo-dendrite and which encloses the soma of the eo-neuron. - fly sheath cell - cell - thecogen cell - - - - The support cell that makes the thecogen dendritic cap - a cuticle-like matrix around the tip of the eo-dendrite and which encloses the soma of the eo-neuron. - Fbbt:00005173 - @@ -7220,9 +2999,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - FBbt:00005130 - cell - neurosecretory neuron @@ -7231,9 +3007,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - FBbt:00005219 - cell - scolopale cell @@ -7242,8 +3015,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - nephrogenic mesenchyme stem cell @@ -7252,8 +3023,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - ligament cell @@ -7262,9 +3031,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - FBbt:00005062 - cell - prohemocyte (sensu Nematoda and Protostomia) @@ -7273,8 +3039,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - attachment cell @@ -7283,9 +3047,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - FBbt:00005063 - cell - hemocyte (sensu Nematoda and Protostomia) @@ -7295,20 +3056,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An elongated fibrocyte that is part of a tendon. The cytoplasm is stretched between the collagen fibres of the tendon. They have a central cell nucleus with a prominent nucleolus. Tendon cells have a well-developed rough endoplasmic reticulum and they are responsible for synthesis and turnover of tendon fibres and ground substance. - muscle attachment cell - cell - tenocyte - tendon cell - - - - An elongated fibrocyte that is part of a tendon. The cytoplasm is stretched between the collagen fibres of the tendon. They have a central cell nucleus with a prominent nucleolus. Tendon cells have a well-developed rough endoplasmic reticulum and they are responsible for synthesis and turnover of tendon fibres and ground substance. - GOC:NV - GOC:tfm - PMID:957445 - @@ -7318,8 +3066,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - socket cell (sensu Nematoda) @@ -7328,8 +3074,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - blood cell (sensu Nematoda and Protostomia) @@ -7338,17 +3082,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An insect immune cell that develops from plasmatocyte. - FBbt:00001688 - cell - podocyte (sensu Diptera) - - - - An insect immune cell that develops from plasmatocyte. - PMID:12930778 - @@ -7356,9 +3090,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - FMA:63847 - cell - crystal cell @@ -7367,16 +3098,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell whose function is determined by its response to an electric signal. - cell - electrically responsive cell - - - - A cell whose function is determined by its response to an electric signal. - FB:ma - @@ -7384,9 +3106,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - FBbt:00001685 - cell - plasmatocyte @@ -7395,9 +3114,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - FBbt:00001689 - cell - procrystal cell @@ -7406,9 +3122,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - FBbt:00001687 - cell - lamellocyte @@ -7417,8 +3130,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - ganglion interneuron @@ -7427,45 +3138,19 @@ Covers cells actively being cultured or stored in a quiescent state for future u - FBbt:00001691 - cell - polygonal cell - - Obsolete. Consult Plant Ontology instead. OBSOLETED, not defined prior to obsoletion. - cell - obsolete phloem element - true - - - - - Obsolete. Consult Plant Ontology instead. OBSOLETED, not defined prior to obsoletion. - GOC:tfm - + - - Obsolete. Use PO:0000332 from Plant Ontology instead. An epidermal cell with a characteristic convoluted anticlinal cell wall that gives a jigsaw like appearance to the lamina. - cell - replaced_by: PO:0000332 - obsolete pavement cell - true - - - - - Obsolete. Use PO:0000332 from Plant Ontology instead. An epidermal cell with a characteristic convoluted anticlinal cell wall that gives a jigsaw like appearance to the lamina. - ISBN:087694289 - + @@ -7473,9 +3158,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - FBbt:00001686 - cell - macrophage (sensu Diptera) @@ -7485,8 +3167,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - CNS interneuron @@ -7495,16 +3175,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell that initiates an electrical signal and passes that signal to another cell. - cell - electrically signaling cell - - - - A cell that initiates an electrical signal and passes that signal to another cell. - FB:ma - @@ -7512,9 +3183,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - FBbt:00005148 - cell - neuroepidermoblast @@ -7523,8 +3191,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - CNS short range interneuron @@ -7533,9 +3199,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - FBbt:00005221 - cell - scolopidial ligament cell @@ -7545,10 +3208,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - BTO:0001277 - CALOHA:TS-0949 - cell - male gamete @@ -7557,9 +3216,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - FBbt:00005219 - cell - scolopidial sheath cell @@ -7568,8 +3224,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - CNS long range interneuron @@ -7580,18 +3234,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An epithelial cell of the hypodermis of flatworms. - WBbt:0007846 - cell - flatworm hypodermal cell - - - - An epithelial cell of the hypodermis of flatworms. - GOC:tfm - http://www.wormatlas.org/hermaphrodite/hypodermis/mainframe.htm - @@ -7599,16 +3242,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell whose nucleus, or nuclei, each contain more than two haploid genomes. - cell - polyploid cell - - - - A cell whose nucleus, or nuclei, each contain more than two haploid genomes. - FB:ma - @@ -7616,40 +3250,13 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell whose nucleus contains a single haploid genome. - cell - haploid cell - - - - A cell whose nucleus contains a single haploid genome. - FB:ma - GOC:tfm - - - OBSOLETE: A classification of cells by the number of haploid genome equivalents of their nucleus or nuclei. - CL:0000000 - CL:0000003 - CL:0000255 - CL:0001034 - cell - This term was made obsolete because there is no difference in meaning between it and 'cell', as any cell with chromosomes can be classified by its ploidy. If you have used this term in annotation, please replace it with cell (CL:0000000), native cell (CL:0000003), eukaryotic cell (CL:0000255) or cell in vitro (CL:0001034) as appropriate. - obsolete cell by ploidy - true - - - - - OBSOLETE: A classification of cells by the number of haploid genome equivalents of their nucleus or nuclei. - FB:ma - GOC:tfm - + @@ -7657,17 +3264,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell whose nucleus has two haploid genomes. - FMA:72300 - cell - diploid cell - - - - A cell whose nucleus has two haploid genomes. - FB:ma - @@ -7675,8 +3272,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - polytene cell @@ -7685,8 +3280,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - endopolyploid cell @@ -7696,18 +3289,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An epithelial cell found in C. elegans that firmly hold the outer body wall and the lips to the inner cylinder of the pharynx in a manner that keeps these organs from breaking apart, while still giving each organ freedom of movement during feeding. - WBbt:0005793 - cell - arcade cell - - - - An epithelial cell found in C. elegans that firmly hold the outer body wall and the lips to the inner cylinder of the pharynx in a manner that keeps these organs from breaking apart, while still giving each organ freedom of movement during feeding. - GOC:tfm - http://www.wormatlas.org/ver1/handbook/hypodermis/hypsupportother.htm#arcadecells - @@ -7715,18 +3297,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An epithelial fate stem cell found in flatworms. - BTO:0003039 - cell - seam cell - - - - An epithelial fate stem cell found in flatworms. - GOC:tfm - http://www.wormatlas.org/hermaphrodite/seam%20cells/mainframe.htm - @@ -7736,8 +3307,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - syncytial epithelial cell @@ -7747,19 +3316,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A free floating cell, including amebocytes and eleocytes, in the coelom of certain animals, especially annelids. - BTO:0002856 - WBbt:0005751 - cell - coelomocyte - - - - A free floating cell, including amebocytes and eleocytes, in the coelom of certain animals, especially annelids. - GOC:tfm - ISBN:0721662544 - @@ -7767,16 +3324,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell whose primary function is to cause growth by stimulating cell division in its immediate cellular environment. - cell - mitogenic signaling cell - - - - A cell whose primary function is to cause growth by stimulating cell division in its immediate cellular environment. - FB:ma - @@ -7784,8 +3332,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - tip cell @@ -7794,18 +3340,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell involved in the elimination of metabolic and foreign toxins, and in maintaining the ionic, acid-base and water balance of biological fluids. - WBbt:0005812 - cell - excretory cell - - - - A cell involved in the elimination of metabolic and foreign toxins, and in maintaining the ionic, acid-base and water balance of biological fluids. - GOC:tfm - PMID:19783135 - @@ -7813,16 +3348,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Forms the terminal part of the cuticle-lined excretory duct of C. elegans. - cell - pore cell - - - - Forms the terminal part of the cuticle-lined excretory duct of C. elegans. - JB:jb - @@ -7830,8 +3356,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - scaffold cell @@ -7840,17 +3364,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A scaffolding cell type found in C. elegans, this cell plays a supportive role to the muscle arms. May also have an endocrine role. - cell - GLR cell - - - - A scaffolding cell type found in C. elegans, this cell plays a supportive role to the muscle arms. May also have an endocrine role. - GOC:tfm - http://wormatlas.psc.edu/hermaphrodite/muscleGLR/mainframe.htm - @@ -7859,8 +3373,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - yolk cell @@ -7869,8 +3381,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - imaginal disc cell @@ -7879,17 +3389,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A pigment cell derived from the neural crest. Contains cartenoid pigments in structures called pterinosomes or xanthosomes. This gives an appearance ranging from a golden yellow to orange and red. - cell - xanthophore - xanthophore cell - - - - A pigment cell derived from the neural crest. Contains cartenoid pigments in structures called pterinosomes or xanthosomes. This gives an appearance ranging from a golden yellow to orange and red. - SANBI:mhl - @@ -7897,17 +3397,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A pigment cell derived from the neural crest. The cell contains flat light-reflecting platelets, probably of guanine, in stacks called reflecting platets or iridisomes. The color-generating components produce a silver, gold, or iridescent color. - cell - guanophore - iridophore - - - - A pigment cell derived from the neural crest. The cell contains flat light-reflecting platelets, probably of guanine, in stacks called reflecting platets or iridisomes. The color-generating components produce a silver, gold, or iridescent color. - SANBI:mhl - @@ -7915,38 +3405,13 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Large, stellate fibroblast found along the network of collagen fibers of the reticulum of the spleen; synthesize the matrix components of the reticulum. - FMA:62877 - reticulum cell - cell - reticular cell - - - - Large, stellate fibroblast found along the network of collagen fibers of the reticulum of the spleen; synthesize the matrix components of the reticulum. - GOC:tfm - ISBN:0517223651 - http://en.wikipedia.org/wiki/Reticular_cell - - - Obsolete. Use PO:0000244 from Plant Ontology instead. In monosporic and bisporic megasporogenesis: the megaspore(s) that will undergo megagametogenesis. - cell - replaced_by: PO:0000244 - obsolete functional megaspore - true - - - - - Obsolete. Use PO:0000244 from Plant Ontology instead. In monosporic and bisporic megasporogenesis: the megaspore(s) that will undergo megagametogenesis. - TAIR:lr - + @@ -7954,16 +3419,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A secretory cell that discharges its product without loss of cytoplasm. - cell - eccrine cell - - - - A secretory cell that discharges its product without loss of cytoplasm. - ISBN:0198547684 - @@ -7971,8 +3427,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - alkali secreting cell @@ -7981,8 +3435,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - vaginal lubricant secreting cell @@ -7992,27 +3444,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A rounded cell that is usually situated next to sinusoids; secretes follicular stimulating hormone (FSH) and luteinizing hormone (LH). - BTO:0002482 - FMA:83100 - delta basophil - follicle stimulating hormone secreting cell - gonadotrope - gonadotrope cell - gonadotroph - gonadotropic cell - pituitary delta cell - cell - gonadtroph - - - - - A rounded cell that is usually situated next to sinusoids; secretes follicular stimulating hormone (FSH) and luteinizing hormone (LH). - GOC:tfm - ISBN:0517223651 - http://en.wikipedia.org/wiki/Gonadotroph - + @@ -8020,16 +3452,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A peptide hormone secreting cell pituitary that produces luteinizing hormone. - cell - luteinizing hormone secreting cell - - - - A peptide hormone secreting cell pituitary that produces luteinizing hormone. - GOC:tfm - @@ -8038,17 +3461,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A peptide hormone cell that secretes prolactin. - cell - prolactin secreting cell - - - - A peptide hormone cell that secretes prolactin. - GOC:tfm - SANBI:mhl - @@ -8056,19 +3469,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell of the intermediate pituitary that produces melanocyte stimulating hormone. - BTO:0002277 - melanotrope - melanotroph - cell - melanocyte stimulating hormone secreting cell - - - - A cell of the intermediate pituitary that produces melanocyte stimulating hormone. - SANBI:mhl - @@ -8076,9 +3477,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - FBbt:00004903 - cell - follicle stem cell @@ -8087,19 +3485,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell with extensive dendritic processes found in the B cell areas (primary follicles and germinal centers) of lymphoid tissue. They are unrelated to the dendritic cell associated with T cells. Follicular dendritic cells have Fc receptors and C3b receptors, but unlike other dendritic cells, they do not process or present antigen in a way that allows recognition by T cells. Instead, they hold antigen in the form of immune complexes on their surfaces for long periods and can present antigen to B cells during an immune response. - BTO:0004267 - FMA:83037 - cell - Due to its unique lineage and distinct function, this is not a type of dendritic cell; CL:0000451. - follicular dendritic cell - - - - A cell with extensive dendritic processes found in the B cell areas (primary follicles and germinal centers) of lymphoid tissue. They are unrelated to the dendritic cell associated with T cells. Follicular dendritic cells have Fc receptors and C3b receptors, but unlike other dendritic cells, they do not process or present antigen in a way that allows recognition by T cells. Instead, they hold antigen in the form of immune complexes on their surfaces for long periods and can present antigen to B cells during an immune response. - ISBN:127520252 - @@ -8107,8 +3493,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - calcitonin secreting cell @@ -8117,18 +3501,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A muscle cell in which the fibers are organised into sarcomeres but in which adjacent myofibrils are offset from each other, producing an oblique banding pattern. - cell - Examples include the somatic muscles of nemotodes and cephalopods. - obliquely striated muscle cell - - - - A muscle cell in which the fibers are organised into sarcomeres but in which adjacent myofibrils are offset from each other, producing an oblique banding pattern. - GOC:DOS - PMID:8720463 - @@ -8136,8 +3509,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - apoptosis fated cell @@ -8147,25 +3518,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An epithelial cell of the parathyroid gland that is arranged in wide, irregular interconnecting columns; responsible for the synthesis and secretion of parathyroid hormone. - BTO:0004712 - CALOHA:TS-2140 - FMA:69078 - parathyroid chief cell - parathyroid gland chief cell - parathyroid hormone secreting cell - principal cell of parathyroid gland - cell - chief cell of parathyroid gland - - - - - An epithelial cell of the parathyroid gland that is arranged in wide, irregular interconnecting columns; responsible for the synthesis and secretion of parathyroid hormone. - FMA:69078 - GOC:tfm - ISBN:0517223651 - + @@ -8173,8 +3526,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - carbohydrate secreting cell @@ -8183,22 +3534,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Fat cells with light coloration and few mitochondria. They contain a scant ring of cytoplasm surrounding a single large lipid droplet or vacuole. - CALOHA:TS-1119 - FMA:83434 - white adipose cell - white fat cell - cell - white adipocyte - white fat cell - - - - Fat cells with light coloration and few mitochondria. They contain a scant ring of cytoplasm surrounding a single large lipid droplet or vacuole. - GOC:tfm - MESH:A11.329.114.500 - @@ -8206,20 +3542,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell from the thermogenic form of adipose tissue found in many species, particularly in newborns and hibernating mammals, but also in lesser amounts in adults of other mammals including humans. Brown fat is capable of rapid liberation of energy and seems to be important in the maintenance of body temperature immediately after birth and upon waking from hibernation. - CALOHA:TS-0099 - FMA:83435 - brown adipocyte - brown adipose cell - cell - brown fat cell - - - - A cell from the thermogenic form of adipose tissue found in many species, particularly in newborns and hibernating mammals, but also in lesser amounts in adults of other mammals including humans. Brown fat is capable of rapid liberation of energy and seems to be important in the maintenance of body temperature immediately after birth and upon waking from hibernation. - MESH:A10.165.114.322 - @@ -8227,22 +3550,8 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. These cells are lineage negative (CD3-negative, CD19-negative, CD34-negative, and CD56-negative). - BTO:0002042 - CALOHA:TS-0194 - FMA:83036 - cell - interdigitating cell - veiled cell - dendritic cell + - - - - A cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. These cells are lineage negative (CD3-negative, CD19-negative, CD34-negative, and CD56-negative). - GOC:add - ISBN:0781735149 - @@ -8250,8 +3559,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - thyroid hormone secreting cell @@ -8261,28 +3568,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Langerhans cell is a conventional dendritic cell that has plasma membrane part CD207. A Langerhans cell is a stellate dendritic cell of myeloid origin, that appears clear on light microscopy and has a dark-staining, indented nucleus and characteristic inclusions (Birbeck granules) in the cytoplasm; Langerhans cells are found principally in the stratum spinosum of the epidermis, but they also occur in other stratified epithelia and have been identified in the lung, lymph nodes, spleen, and thymus. - BTO:0000705 - CALOHA:TS-2375 - FMA:63072 - LC - Langerhans' cell - cell - Originally described in the dendritic cell ontology (DC_CL:0000021 )(PMID:19243617). These cells are also CD1a-high, CD14-negative, CD207-positive (langerin), CD324-positive (E-cadherin), and DCIR-positive. They reside in the epidermis. - Langerhans cell - - - - - Langerhans cell is a conventional dendritic cell that has plasma membrane part CD207. A Langerhans cell is a stellate dendritic cell of myeloid origin, that appears clear on light microscopy and has a dark-staining, indented nucleus and characteristic inclusions (Birbeck granules) in the cytoplasm; Langerhans cells are found principally in the stratum spinosum of the epidermis, but they also occur in other stratified epithelia and have been identified in the lung, lymph nodes, spleen, and thymus. - GOC:add - GOC:amm - GO_REF:0000031 - ISBN:0721601464 - ISBN:0781735149 - PMCID:PMC2346585 - PMID:17850486 - + @@ -8290,43 +3576,13 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell capable of producing epinephrine. Epiniphrine is synthesized from norepiniphrine by the actions of the phenylethanolamine N-methyltransferase enzyme, which is expressed in the adrenal glands, androgenic neurons, and in other cell types. - adrenaline secreting cell - epinephrin secreting cell - cell - epinephrine secreting cell - - - - - A cell capable of producing epinephrine. Epiniphrine is synthesized from norepiniphrine by the actions of the phenylethanolamine N-methyltransferase enzyme, which is expressed in the adrenal glands, androgenic neurons, and in other cell types. - GOC:tfm - PMID:12438093 - - - - - adrenaline secreting cell - GO:0048242 - + - - Obsolete. Use PO:0004531 from Plant Ontology instead. A cell characterized by conspicuous and rather stable accumulation of starch. - cell - replaced_by: PO:0004531 - obsolete starch sheath cell - true - - - - - Obsolete. Use PO:0004531 from Plant Ontology instead. A cell characterized by conspicuous and rather stable accumulation of starch. - ISBN:044174520 - + @@ -8334,8 +3590,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - mineralocorticoid secreting cell @@ -8344,8 +3598,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - biogenic amine secreting cell @@ -8354,19 +3606,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell type that secretes 5-Hydroxytryptamine (serotonin). - 5-HT secreting cell - 5-Hydroxytryptamine secreting cell - cell - serotonin secreting cell - - - - A cell type that secretes 5-Hydroxytryptamine (serotonin). - GOC:tfm - PMID:19630576 - @@ -8374,20 +3614,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell capable of producting norepiniphrine. Norepiniphrine is a catecholamine with multiple roles including as a hormone and a neurotransmitter. In addition, epiniphrine is synthesized from norepiniphrine by the actions of the phenylethanolamine N-methyltransferase enzyme. - noradrenaline secreting cell - norepinephrin secreting cell - norepinephrine secreting cell - cell - noradrenergic cell - - - - A cell capable of producting norepiniphrine. Norepiniphrine is a catecholamine with multiple roles including as a hormone and a neurotransmitter. In addition, epiniphrine is synthesized from norepiniphrine by the actions of the phenylethanolamine N-methyltransferase enzyme. - GOC:tfm - ISBN:068340007X - @@ -8395,8 +3622,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - glucocorticoid secreting cell @@ -8405,9 +3630,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - FBbt:00003219 - cell - adepithelial cell @@ -8417,18 +3639,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An epidermal cell that secretes chitinous cuticle from its apical side. - cell - While insect epidermis is generally columnar/cuboidal, there are certainly well studied cases where it is not (e.g.- Rhodnius prolixus when starved). So it would be safer to add this as a differentium for particular species where this is known. -DSJ. - epidermal cell (sensu arthropoda) - - - - An epidermal cell that secretes chitinous cuticle from its apical side. - FlyBase:ds - ISBN:ISBN:978-0801481253 - @@ -8437,18 +3648,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An epidermal progenitor cell that arises from neuroectoderm and in turn gives rise to the epidermal sheath of ventral and cephalic regions. - FBbt:00004994 - cell - epidermoblast - - - - An epidermal progenitor cell that arises from neuroectoderm and in turn gives rise to the epidermal sheath of ventral and cephalic regions. - GOC:tfm - PMID:7576311 - @@ -8456,9 +3656,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - FBbt:00001666 - cell - cardioblast (sensu Arthropoda) @@ -8468,35 +3665,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A peptide hormone secreting cell that produces adrenocorticotropin, or corticotropin. - CL:0000640 - ACTH secreting cell - adrenocorticotrophic hormone secreting cell - corticotrophin hormone secreting cell - corticotropin hormone secreting cell - corticotropin secreting cell - cell - adrenocorticotropic hormone secreting cell - - - - - A peptide hormone secreting cell that produces adrenocorticotropin, or corticotropin. - GOC:tfm - SANBI:mhl - - - - - ACTH secreting cell - GO:0051458 - - - - - corticotropin secreting cell - GO:0051458 - + @@ -8505,9 +3674,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - FBbt:00005147 - cell - neuroglioblast @@ -8516,9 +3682,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - FBbt:00005149 - cell - ganglion mother cell @@ -8527,27 +3690,13 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - digestive enzyme secreting cell - - Obsolete. Use PO:0000076 from Plant Ontology instead. OBSOLETE, use term from Plant Ontology. Parenchyma cells containing chloroplasts; a component of leaf mesophyll and other green parenchyma tissue. - cell - replaced_by: PO:0000076 - obsolete chlorenchyma cell - true - - - - - Obsolete. Use PO:0000076 from Plant Ontology instead. OBSOLETE, use term from Plant Ontology. Parenchyma cells containing chloroplasts; a component of leaf mesophyll and other green parenchyma tissue. - ISBN:0471245208 - + @@ -8555,16 +3704,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell whose primary function is to protect the organism. - cell - defensive cell - - - - A cell whose primary function is to protect the organism. - JB:jb - @@ -8573,46 +3713,13 @@ Covers cells actively being cultured or stored in a quiescent state for future u - an insect renal cell that filters hemolymph and is found with other pericardial nephrocytes in two rows flanking the dorsal vessel. - FBbt:00005058 - pericardial cell - cell - pericardial nephrocyte - - - - - an insect renal cell that filters hemolymph and is found with other pericardial nephrocytes in two rows flanking the dorsal vessel. - FBbt:00003184 - GO:0061320 - GOC:tfm - PMID:19783135 - - - - - pericardial cell - FBbt:00005058 - GO:0061320 - + - - Obsolete. Use PO:0000245 from Plant Ontology instead. In monosporic and bisporic megasporogenesis: the megaspore(s) that do not participate in megagametogenesis. - cell - replaced_by: PO:0000245 - obsolete degenerate megaspore - true - - - - - Obsolete. Use PO:0000245 from Plant Ontology instead. In monosporic and bisporic megasporogenesis: the megaspore(s) that do not participate in megagametogenesis. - TAIR:lr - + @@ -8620,21 +3727,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A basophil cell of the anterior pituitary that produces thyroid stimulating hormone, thyrotrophin. This cell type is elongated, polygonal and lie in clusters towards the adenohypophyseal center. - FMA:83099 - beta-basophil - thyroid stimulating hormone secreting cell - thyrotrope - cell - thyrotroph - - - - A basophil cell of the anterior pituitary that produces thyroid stimulating hormone, thyrotrophin. This cell type is elongated, polygonal and lie in clusters towards the adenohypophyseal center. - ISBN:0517223651 - SANBI:mhl - @@ -8642,18 +3735,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - FBbt:00004904 - ovarian follicle cell - cell - Editors note: check this. Currently used in goxp - follicle cell - - - - ovarian follicle cell - GO:0007297 - @@ -8661,16 +3743,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A peptide hormone secreting cell that secretes oxytocin stimulating hormone - cell - oxytocin stimulating hormone secreting cell - - - - A peptide hormone secreting cell that secretes oxytocin stimulating hormone - GO:tfm - @@ -8678,16 +3751,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A peptide hormone secreting cell that secretes vasopressin stimulating hormone - cell - vasopressin stimulating hormone secreting cell - - - - A peptide hormone secreting cell that secretes vasopressin stimulating hormone - GO:tfm - @@ -8695,16 +3759,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A peptide hormone secreting cell that secretes secretin stimulating hormone - cell - secretin stimulating hormone secreting cell - - - - A peptide hormone secreting cell that secretes secretin stimulating hormone - GO:tfm - @@ -8712,16 +3767,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A peptide hormone secreting cell that secretes cholecystokin stimulating hormone - cell - cholecystokin stimulating hormone secreting cell - - - - A peptide hormone secreting cell that secretes cholecystokin stimulating hormone - GO:tfm - @@ -8729,16 +3775,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An endocrine cell that secretes juvenile hormone. - cell - juvenile hormone secreting cell - - - - An endocrine cell that secretes juvenile hormone. - GO:tfm - @@ -8746,16 +3783,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A peptide hormone secreting cell that secretes cholecystokin stimulating hormone - cell - bombesin stimulating hormone secreting cell - - - - A peptide hormone secreting cell that secretes cholecystokin stimulating hormone - GO:tfm - @@ -8764,24 +3792,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Mast cell subtype whose granules contain both the serine proteases tryptase and chymase. These cells are primarily found in connective tissue, such as the peritoneal cavity, skin, and intestinal submucosa. Their development is T-cell independent. - MC(TC) - MCTC - TC mast cells - cell - They are CD88-positive. The cytoplasmic granules contain high levels of histamine and heparin (mouse) or major neutral proteases, tryptase, chymase, carboxypeptidase A, and cathepsin G (humans). Reportedly, they cannot produce leukotrienes (LTC4) and IL-4. They are reportedly very heterogeneous depending upon location and can convert to the MC(T) phenotype. - connective tissue type mast cell - - - - - Mast cell subtype whose granules contain both the serine proteases tryptase and chymase. These cells are primarily found in connective tissue, such as the peritoneal cavity, skin, and intestinal submucosa. Their development is T-cell independent. - GOC:add - GOC:dsd - GOC:tfm - PMID:19923473 - PMID:9354811 - + @@ -8789,23 +3800,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Mast cell subtype that contains only the serine protease trypase in its granules. These cells are primarily found in mucosal tissue, such as intestinal mucosa and alveoli. They depend upon T-cells for development of phenotype. - MC(T) - MCT - T mast cells - cell - They are CD88-negative. The cytoplasmic granules contain low levels of histamine and high levels of chondroitin sulfate (mouse) or major neutral proteases and tryptase (humans). Additionally, they can produce leukotrienes (LTC4), IL-5, IL-6, and low levels of IL-4. They are reportedly very heterogeneous depending upon location and can convert to the MC(T) phenotype. - mucosal type mast cell - - - - - Mast cell subtype that contains only the serine protease trypase in its granules. These cells are primarily found in mucosal tissue, such as intestinal mucosa and alveoli. They depend upon T-cells for development of phenotype. - GOC:add - GOC:dsd - PMID:19923473 - PMID:9354811 - + @@ -8815,27 +3810,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A large binucleate cell that forms a 'garland' around the anterior end of the proventriculus (cardia) at its junction with the esophagus in both adults and larvae flies. Each cell is surrounded by a basement membrane and there are numerous micro-invaginations (lacunae) extending from the surface into the cytoplasm. At the mouth of each lacuna is a doubled filament forming a specialised filtration system (diaphragm). The filtrate is endocytosed from the lacunae. - garland nephrocyte - BTO:0004596 - FBbt:00005059 - cell - garland cell - - - - - A large binucleate cell that forms a 'garland' around the anterior end of the proventriculus (cardia) at its junction with the esophagus in both adults and larvae flies. Each cell is surrounded by a basement membrane and there are numerous micro-invaginations (lacunae) extending from the surface into the cytoplasm. At the mouth of each lacuna is a doubled filament forming a specialised filtration system (diaphragm). The filtrate is endocytosed from the lacunae. - GOC:tfm - PMID:19783135 - fbbt:00005059 - - - - - garland nephrocyte - GO:0061321 - + @@ -8843,18 +3818,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A large secretory cell found in clusters underlying the epidermis of the abdominal segments of larval abdominal segments. - FBbt:00004995 - cell - oenocyte - - - - A large secretory cell found in clusters underlying the epidermis of the abdominal segments of larval abdominal segments. - GOC:bf - PMID:11171397 - @@ -8862,16 +3826,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A photoreceptor cell that detects visible light. - cell - visible light photoreceptor cell - - - - A photoreceptor cell that detects visible light. - GOC:tfm - @@ -8879,8 +3834,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - scotopic photoreceptor cell @@ -8889,21 +3842,13 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - photopic photoreceptor cell - - OBSOLETE: A cell responsible for spontaneous cytotoxicity of a variety of tumor cells without prior immunization. These natural killer cells are found in non-immune humans and experimental animals and are thought by some to be the same as killer cells (killing by antibody-dependent cell cytotoxicity), but they can also kill in the absence of antibody. - cell - This term had an incorrect definition and was overly broad. Consider using 'cytotoxic T cell ; CL:0000910' (in most cases) or another lymphocyte cell type if cytotoxicity is shown to be part of the cell's phenotype in a particular experimental situation. - obsolete cytotoxic T cell - true - + @@ -8912,39 +3857,13 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A CD4-positive, alpha-beta T cell that cooperates with other lymphocytes via direct contact or cytokine release to initiate a variety of immune functions. - CALOHA:TS-1146 - FMA:70572 - CD4-positive T-helper cell - CD4-positive helper T lymphocyte - CD4-positive helper T-cell - CD4-positive helper T-lymphocyte - cell - CD4-positive helper T cell - - - - - A CD4-positive, alpha-beta T cell that cooperates with other lymphocytes via direct contact or cytokine release to initiate a variety of immune functions. - GOC:add - GOC:pam - GOC:tfm - GO_REF:0000031 - ISBN:0781735149 - MESH:A11.118.637.555.567.569.200.400 - + - - OBSOLETE: Subpopulation of CD4+ cells which induce CD8+ suppressor T cells to suppress antibody production by B cells. They also stimulate other cellular immune responses. - cell - This term was defined too narrowly; consider using the term 'regulatory T cell ; CL:0000815' instead. - obsolete regulatory T cell - true - + @@ -8952,16 +3871,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A photoreceptor cell that detects ultraviolet light. - cell - UV sensitive photoreceptor cell - - - - A photoreceptor cell that detects ultraviolet light. - GOC:tfm - @@ -8969,16 +3879,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A photoreceptor cell that is sensitive to blue light. - cell - blue sensitive photoreceptor cell - - - - A photoreceptor cell that is sensitive to blue light. - GO:tfm - @@ -8986,16 +3887,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A photoreceptor cell that is sensitive to green light. - cell - green sensitive photoreceptor cell - - - - A photoreceptor cell that is sensitive to green light. - GO:tfm - @@ -9003,16 +3895,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A photoreceptor cell that is sensitive to red light. - cell - red sensitive photoreceptor cell - - - - A photoreceptor cell that is sensitive to red light. - GO:tfm - @@ -9020,18 +3903,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An interneuron (also called relay neuron, association neuron or local circuit neuron) is a multipolar neuron which connects afferent neurons and efferent neurons in neural pathways. Like motor neurons, interneuron cell bodies are always located in the central nervous system (CNS). - FMA:84776 - cell - inhibitory interneuron - - - - An interneuron (also called relay neuron, association neuron or local circuit neuron) is a multipolar neuron which connects afferent neurons and efferent neurons in neural pathways. Like motor neurons, interneuron cell bodies are always located in the central nervous system (CNS). - GOC:tfm - http://en.wikipedia.org/wiki/Interneuron - @@ -9039,19 +3911,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A connective tissue cell of an organ found in the loose connective tissue. These are most often associated with the uterine mucosa and the ovary as well as the hematopoietic system and elsewhere. - BTO:0002064 - FMA:83624 - cell - stromal cell - - - - A connective tissue cell of an organ found in the loose connective tissue. These are most often associated with the uterine mucosa and the ovary as well as the hematopoietic system and elsewhere. - GOC:tfm - MESH:A11.329.830 - @@ -9060,8 +3920,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - follicular epithelial cell @@ -9071,20 +3929,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A supporting cell for the developing female gamete in the ovary of mammals. They develop from the coelomic epithelial cells of the gonadal ridge. Granulosa cells form a single layer around the mammalian oocyte in the primordial ovarian follicle and advance to form a multilayered cumulus oophorus surrounding the ovum in the Graafian follicle. The major functions of granulosa cells include the production of steroids and LH receptors. - BTO:0000542 - CALOHA:TS-0729 - FMA:18718 - granulosa cell of ovary - cell - granulosa cell - - - - A supporting cell for the developing female gamete in the ovary of mammals. They develop from the coelomic epithelial cells of the gonadal ridge. Granulosa cells form a single layer around the mammalian oocyte in the primordial ovarian follicle and advance to form a multilayered cumulus oophorus surrounding the ovum in the Graafian follicle. The major functions of granulosa cells include the production of steroids and LH receptors. - MESH:A05.360.319.114.630.535.200 - @@ -9093,18 +3938,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell found throughout the gastrointestinal tract and in the pancreas. They secrete somatostatin in both an endocrine and paracrine manner. Somatostatin inhibits gastrin, cholecystokinin, insulin, glucagon, pancreatic enzymes, and gastric hydrochloric acid. A variety of substances which inhibit gastric acid secretion (vasoactive intestinal peptide, calcitonin gene-related peptide, cholecystokinin, beta-adrenergic agonists, and gastric inhibitory peptide) are thought to act by releasing somatostatin. - FMA:62935 - D cell - cell - type D enteroendocrine cell - - - - A cell found throughout the gastrointestinal tract and in the pancreas. They secrete somatostatin in both an endocrine and paracrine manner. Somatostatin inhibits gastrin, cholecystokinin, insulin, glucagon, pancreatic enzymes, and gastric hydrochloric acid. A variety of substances which inhibit gastric acid secretion (vasoactive intestinal peptide, calcitonin gene-related peptide, cholecystokinin, beta-adrenergic agonists, and gastric inhibitory peptide) are thought to act by releasing somatostatin. - MESH:A03.492.766.440.175 - @@ -9113,18 +3947,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A flattened stroma cell forming a sheath or theca outside the basal lamina lining the mature ovarian follicle. Thecal interstitial or stromal cells are steroidogenic, and produce primarily androgens which serve as precusors of estrogens in the granulosa cells. - BTO:0002850 - FMA:18690 - cell - theca cell - - - - A flattened stroma cell forming a sheath or theca outside the basal lamina lining the mature ovarian follicle. Thecal interstitial or stromal cells are steroidogenic, and produce primarily androgens which serve as precusors of estrogens in the granulosa cells. - MESH:A05.360.319.114.630.535.400 - @@ -9133,20 +3956,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A enteroendocrine cell part of the glands of the gastric mucosa. They produce histamine and peptides such as chromogranins. This cell type respond to gastrin by releasing histamine which acts as a paracrine stimulator of the release of hydrochloric acid from the gastric parietal cells. - BTO:0002692 - ECL - cell - Consider enterochromaffin cell (CL:0002065). For several years this cell type was "enterochromaffin cell" despite a MESH dbxref and a free text definition that clearly meant enterochromaffin-like cell. - enterochromaffin-like cell - - - - A enteroendocrine cell part of the glands of the gastric mucosa. They produce histamine and peptides such as chromogranins. This cell type respond to gastrin by releasing histamine which acts as a paracrine stimulator of the release of hydrochloric acid from the gastric parietal cells. - GOC:tfm - MESH:A06.224.365 - @@ -9154,16 +3964,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A peptide hormone secreting cell that secretes substance P. - cell - substance P secreting cell - - - - A peptide hormone secreting cell that secretes substance P. - GO:tfm - @@ -9171,16 +3972,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An endorphine cell that secretes enkephalin. - cell - enkephalin secreting cell - - - - An endorphine cell that secretes enkephalin. - GO:tfm - @@ -9188,16 +3980,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A peptide hormone secreting cell that secretes endorphin. - cell - endorphin secreting cell - - - - A peptide hormone secreting cell that secretes endorphin. - GO:tfm - @@ -9208,21 +3991,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An endocrine cell found in the pyloric gland mucosa (antral mucosa) of the stomach of mammals and responsible for the secretion of gastrin and enkephalin. Most abundant in pyloric antrum, pyramidal in form with a narrow apex bearing long microvilli. - BTO:0004108 - FMA:67609 - G cell - cell - type G enteroendocrine cell - - - - An endocrine cell found in the pyloric gland mucosa (antral mucosa) of the stomach of mammals and responsible for the secretion of gastrin and enkephalin. Most abundant in pyloric antrum, pyramidal in form with a narrow apex bearing long microvilli. - GOC:tfm - ISBN:0517223651 - MESH:A03.492.766.440.300 - @@ -9230,16 +3999,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A peptide hormone secreting cell that secretes gastrin. - cell - gastrin secreting cell - - - - A peptide hormone secreting cell that secretes gastrin. - GO:tfm - @@ -9249,20 +4009,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An epithelial cell found in the basal part of the intestinal glands (crypts of Lieberkuhn) including the appendix. Paneth cells synthesize and secrete lysozyme and cryptdins. Numerous in the deeper parts of the intestinal crypts, particularly in the duodenum, rich in zinc, contain large acidophilic granules, with irregular apical microvilli and prominent membrane-bound vacuoles containing matrix. - BTO:0000993 - FMA:62897 - cell - paneth cell - - - - An epithelial cell found in the basal part of the intestinal glands (crypts of Lieberkuhn) including the appendix. Paneth cells synthesize and secrete lysozyme and cryptdins. Numerous in the deeper parts of the intestinal crypts, particularly in the duodenum, rich in zinc, contain large acidophilic granules, with irregular apical microvilli and prominent membrane-bound vacuoles containing matrix. - GOC:tfm - ISBN:0517223651 - MESH:A03.492.411.369.700 - @@ -9270,16 +4017,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A peptide hormone secreting cell that secretes androgen binding protein. - cell - androgen binding protein secreting cell - - - - A peptide hormone secreting cell that secretes androgen binding protein. - GO:tfm - @@ -9287,17 +4025,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A paracrine cell is a secretory cell that secretes an agonist into intercellular spaces in which it diffuses to a target cell other than that which produced it. - cell - paracrine cell - - - - A paracrine cell is a secretory cell that secretes an agonist into intercellular spaces in which it diffuses to a target cell other than that which produced it. - GOC:tfm - ISBN:0198529171 - @@ -9306,21 +4034,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A precursor cell destined to differentiate into cardiac muscle cell. - CL:0000714 - FMA:84797 - cardiac muscle progenitor cell - cardiomyocyte progenitor cell - cell - cardiac muscle myoblast - - - - A precursor cell destined to differentiate into cardiac muscle cell. - GOC:tfm - MESH:A11.635.470 - @@ -9328,27 +4042,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A precursor cell destined to differentiate into smooth muscle myocytes. - FMA:84798 - myoblast, smooth muscle - cell - satellite cell - smooth muscle myoblast - - - - - A precursor cell destined to differentiate into smooth muscle myocytes. - GOC:tfm - MESH:A11.635.510 - MESH:D032390 - - - - - myoblast, smooth muscle - MESH:D032390 - + @@ -9356,18 +4050,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A myoblast that differentiates into skeletal muscle fibers. - FMA:84799 - skeletal myoblast - cell - skeletal muscle myoblast - - - - A myoblast that differentiates into skeletal muscle fibers. - SANBI:mhl - @@ -9376,21 +4059,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A non-neuronal cell that surrounds the neuronal cell bodies of the ganglia. - FMA:54550 - perineural satellite cell - perineuronal satellite oligodendroglial cell - satellite oligodendrocyte - cell - perineuronal satellite cell - - - - A non-neuronal cell that surrounds the neuronal cell bodies of the ganglia. - GOC:tfm - MESH:A08.340.685 - @@ -9398,17 +4067,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A type of foam cell derived from a macrophage containing lipids in small vacuoles and typically seen in atherolosclerotic lesions, as well as other conditions. - cell - macrophage derived foam cell - - - - A type of foam cell derived from a macrophage containing lipids in small vacuoles and typically seen in atherolosclerotic lesions, as well as other conditions. - GOC:add - PMID:20213546 - @@ -9416,16 +4075,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A phagocyte in vertebrates that is able to phagocytosis. - cell - phagocyte (sensu Vertebrata) - - - - A phagocyte in vertebrates that is able to phagocytosis. - GOC:tfm - @@ -9433,16 +4083,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A phagocyte from organisms in the Nematoda or Protostomia clades. - cell - phagocyte (sensu Nematoda and Protostomia) - - - - A phagocyte from organisms in the Nematoda or Protostomia clades. - GOC:tfm - @@ -9450,8 +4091,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - prokaryotic cell @@ -9460,26 +4099,14 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - fungal cell + - - OBSOLETE: The reproductive structure of bacteria, fungi and cryptograms. - cell - obsolete spore - true - - - - - OBSOLETE: The reproductive structure of bacteria, fungi and cryptograms. - ISBN:08199377X - + @@ -9487,19 +4114,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell from the inner layer of the trophoblast of the early mammalian embryo that gives rise to the outer surface and villi of the chorion. Mononuclear crytoblasts fuse to give rise to a multinuclear cytotrophoblast. - FMA:83042 - Langhans' cell - cell - mononuclear cytotrophoblast cell - - - - A cell from the inner layer of the trophoblast of the early mammalian embryo that gives rise to the outer surface and villi of the chorion. Mononuclear crytoblasts fuse to give rise to a multinuclear cytotrophoblast. - GOC:tfm - ISBN:0323052908 - @@ -9507,17 +4122,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell, usually of bacteria or yeast, which has partially lost its cell wall. - sphaeroplast - cell - spheroplast - - - - A cell, usually of bacteria or yeast, which has partially lost its cell wall. - MESH:A11.868 - @@ -9526,21 +4131,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell from the outer syncytial layer of the trophoblast of an early mammalian embryo. It It secretes hCG in order to maintain progesterone secretion and sustain a pregnancy. - FMA:83043 - plasmidotrophoblast - syncytial trophoblast - syntrophoblast - cell - syncytiotrophoblast cell - - - - A cell from the outer syncytial layer of the trophoblast of an early mammalian embryo. It It secretes hCG in order to maintain progesterone secretion and sustain a pregnancy. - GOC:tfm - ISBN:0323052908 - @@ -9548,19 +4139,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A neuron which conveys sensory information centrally from the periphery. - FMA:87653 - input neuron - cell - afferent neuron - - - - A neuron which conveys sensory information centrally from the periphery. - GOC:tfm - MESH:A08.663.650 - @@ -9568,17 +4147,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A neuron which sends impulses peripherally to activate muscles or secretory cells. - output neuron - cell - efferent neuron - - - - A neuron which sends impulses peripherally to activate muscles or secretory cells. - MESH:A08.663.655 - @@ -9586,17 +4155,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A nerve cell where transmission is mediated by nitric oxide. - FMA:84792 - cell - nitrergic neuron - - - - A nerve cell where transmission is mediated by nitric oxide. - MESH:A08.663.748 - @@ -9604,8 +4163,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - pigmented epithelial cell @@ -9614,8 +4171,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - primary neuron @@ -9625,8 +4180,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - primary sensory neuron @@ -9635,8 +4188,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - CAP motoneuron @@ -9646,9 +4197,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - FMA:83619 - cell - primary motor neuron @@ -9658,8 +4206,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - primary interneuron @@ -9668,8 +4214,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - secondary neuron @@ -9679,63 +4223,25 @@ Covers cells actively being cultured or stored in a quiescent state for future u - FMA:83620 - cell - secondary motor neuron - - Obsolete. Use PO:0020093 from Plant Ontology instead. OBSOLETE, use term from plant ontology. A cell located at the chalazal end of the mature embryo sac in angiosperms. - cell - replaced_by: PO:0020093 - obsolete antipodal cell - true - - - - - Obsolete. Use PO:0020093 from Plant Ontology instead. OBSOLETE, use term from plant ontology. A cell located at the chalazal end of the mature embryo sac in angiosperms. - ISBN:047125208 - + - - Obsolete. Use PO:0000349 from Plant Ontology instead. A relatively unspecialized cell that will give rise to specialized cell types of the epidermis. - cell - replaced_by: PO:0000349 - obsolete epidermal initial - true - - - - - Obsolete. Use PO:0000349 from Plant Ontology instead. A relatively unspecialized cell that will give rise to specialized cell types of the epidermis. - TAIR:lr - + - - OBSOLETE: A cell in a tissue that markedly differs in form, size, or contents from other cells in the same tissue. - cell - obsolete idioblast - true - - - - - OBSOLETE: A cell in a tissue that markedly differs in form, size, or contents from other cells in the same tissue. - ISBN:0471245208 - + @@ -9745,26 +4251,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system. - BTO:0000938 - CALOHA:TS-0683 - FBbt:00005106 - FMA:54527 - VHOG:0001483 - WBbt:0003679 - nerve cell - cell - These cells are also reportedly CD4-negative and CD200-positive. They are also capable of producing CD40L and IFN-gamma. - neuron - - - - - The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system. - MESH:A08.663 - MESH:D009474 - http://en.wikipedia.org/wiki/Neuron - + @@ -9773,20 +4260,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell that originates from the neural crest and differentiates into a pigment cell. - BTO:0003217 - FMA:83377 - cell - Derived from UBERON:0002342 neural crest. - melanoblast - - - - A cell that originates from the neural crest and differentiates into a pigment cell. - GOC:tfm - SANBI:mhl - @@ -9795,42 +4269,14 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin. - BTO:0000775 - CALOHA:TS-0583 - FMA:62863 - VHOG:0001535 - cell - Editors note: consider adding taxon constraint to vertebrata (PMID:18025161) - lymphocyte - - - - - A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin. - GOC:add - ISBN:0683073696 - ISBN:0781735149 - + + - - Obsolete. Use PO:0000289 from Plant Ontology instead. One of the series of cellular components of a sieve tube. It shows a more or less pronounced differentiation between sieve plates (wide pores) and lateral sieve areas (narrow pores). Also sieve tube element and the obsolete sieve tube segment. - sieve tube element - cell - replaced_by: PO:0000289 - obsolete sieve tube member - true - - - - - Obsolete. Use PO:0000289 from Plant Ontology instead. One of the series of cellular components of a sieve tube. It shows a more or less pronounced differentiation between sieve plates (wide pores) and lateral sieve areas (narrow pores). Also sieve tube element and the obsolete sieve tube segment. - ISBN:0471245208 - + @@ -9838,8 +4284,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - slowly adapting mechanoreceptor cell @@ -9848,46 +4292,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive, CXCR3-positive, CCR6-negative, and is capable of producing interferon-gamma. - BTO:0001678 - FMA:84382 - T helper cells type 1 - T(H)-1 cell - Th1 CD4+ T cell - Th1 T cell - Th1 T lymphocyte - Th1 T-cell - Th1 T-lymphocyte - Th1 cell - helper T cell type 1 - cell - This cell type is compatible with the HIPC Lyoplate markers for 'Th1 CD4+ T cell', but its logical definition includes additional known characteristics of T-helper 1 T cells. - T-helper 1 cell - - - - - A CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive, CXCR3-positive, CCR6-negative, and is capable of producing interferon-gamma. - GOC:add - GOC:pam - GOC:tfm - GO_REF:0000031 - PMID:19375293 - PMID:20303875 - PMID:22343568 - - - - - T helper cells type 1 - PMID:9419219 - - - - - Th1 CD4+ T cell - PMID:22343568 - + @@ -9896,39 +4301,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A CD4-positive, alpha-beta T cell that has the phenotype GATA-3-positive, CXCR3-negative, CCR6-negative, and is capable of producing interleukin-4. - BTO:0001679 - FMA:84385 - T helper cells type 2 - T(H)-2 cell - Th2 T cell - Th2 T lymphocyte - Th2 T-cell - Th2 T-lymphocyte - Th2 cell - helper T cell type 2 - cell - This cell type is compatible with the HIPC Lyoplate markers for 'non-Th1/Th17 CD4+ T cell' (see CL:0001051), but includes the additional necessary and sufficient conditions to allow classification as a T-helper 2 T cell. - T-helper 2 cell - - - - - A CD4-positive, alpha-beta T cell that has the phenotype GATA-3-positive, CXCR3-negative, CCR6-negative, and is capable of producing interleukin-4. - GOC:add - GOC:pam - GOC:tfm - GO_REF:0000031 - PMID:19375293 - PMID:20103781 - PMID:22343568 - - - - - T helper cells type 2 - PMID:9419219 - + @@ -9937,27 +4310,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An immature, nucleated erythrocyte occupying the stage of erythropoeisis that follows formation of erythroid progenitor cells. This cell is CD71-positive, has both a nucleus and a nucleolus, and lacks hematopoeitic lineage markers. - FMA:83518 - rubriblast - cell - pronormoblast - proerythroblast - - - - - An immature, nucleated erythrocyte occupying the stage of erythropoeisis that follows formation of erythroid progenitor cells. This cell is CD71-positive, has both a nucleus and a nucleolus, and lacks hematopoeitic lineage markers. - ISBN:0721601464 - MESH:A11.118.290.350.200 - PMID:1638021 - - - - - rubriblast - ISBN:0721601464 - + @@ -9965,9 +4318,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - - animal cell @@ -9976,46 +4326,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A nucleated immature erythrocyte, having cytoplasm generally similar to that of the earlier proerythroblast but sometimes even more basophilic, and usually regular in outline. The nucleus is still relatively large, but the chromatin strands are thicker and more deeply staining, giving a coarser appearance; the nucleoli have disappeared. This cell is CD71-positive and lacks hematopoeitic lineage markers. - FMA:83505 - basophilic normoblast - early erythroblast - early normoblast - prorubricyte - cell - basophilic erythroblast - - - - - A nucleated immature erythrocyte, having cytoplasm generally similar to that of the earlier proerythroblast but sometimes even more basophilic, and usually regular in outline. The nucleus is still relatively large, but the chromatin strands are thicker and more deeply staining, giving a coarser appearance; the nucleoli have disappeared. This cell is CD71-positive and lacks hematopoeitic lineage markers. - GOC:tfm - ISBN:0721601464 - - - - - basophilic normoblast - ISBN:0721601464 - - - - - early erythroblast - ISBN:0721601464 - - - - - early normoblast - ISBN:0721601464 - - - - - prorubricyte - ISBN:0721601464 - + @@ -10023,59 +4334,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A nucleated, immature erythrocyte in which the nucleus occupies a relatively smaller part of the cell than in its precursor, the basophilic erythroblast. The cytoplasm is beginning to acquire hemoglobin and thus is no longer a purely basophilic, but takes on acidophilic aspects, which becomes progressively more marked as the cell matures. The chromatin of the nucleus is arranged in coarse, deeply staining clumps. This cell is CD71-positive and lacks hematopoeitic lineage markers. - FMA:83506 - intermediate erythroblast - intermediate normoblast - polychromatic erythroblast - polychromatic normoblast - polychromatophilic normoblast - rubricyte - cell - polychromatophilic erythroblast - - - - - A nucleated, immature erythrocyte in which the nucleus occupies a relatively smaller part of the cell than in its precursor, the basophilic erythroblast. The cytoplasm is beginning to acquire hemoglobin and thus is no longer a purely basophilic, but takes on acidophilic aspects, which becomes progressively more marked as the cell matures. The chromatin of the nucleus is arranged in coarse, deeply staining clumps. This cell is CD71-positive and lacks hematopoeitic lineage markers. - ISBN:0721601464 - - - - - intermediate erythroblast - ISBN:0721601464 - - - - - intermediate normoblast - ISBN:0721601464 - - - - - polychromatic erythroblast - ISBN:0721601464 - - - - - polychromatic normoblast - ISBN:0721601464 - - - - - polychromatophilic normoblast - ISBN:0721601464 - - - - - rubricyte - ISBN:0721601464 - + @@ -10083,8 +4342,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - unimodal nocireceptor @@ -10093,46 +4350,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - The final stage of the nucleated, immature erythrocyte, before nuclear loss. Typically the cytoplasm is described as acidophilic, but it still shows a faint polychromatic tint. The nucleus is small and initially may still have coarse, clumped chromatin, as in its precursor, the polychromatophilic erythroblast, but ultimately it becomes pyknotic, and appears as a deeply staining, blue-black, homogeneous structureless mass. The nucleus is often eccentric and sometimes lobulated. - FMA:84646 - acidophilic erythroblast - eosinophilic erythroblast - late erythoblast - orthochromatic normoblast - pyknotic eto enrythroblast - cell - orthochromatic erythroblast - - - - - The final stage of the nucleated, immature erythrocyte, before nuclear loss. Typically the cytoplasm is described as acidophilic, but it still shows a faint polychromatic tint. The nucleus is small and initially may still have coarse, clumped chromatin, as in its precursor, the polychromatophilic erythroblast, but ultimately it becomes pyknotic, and appears as a deeply staining, blue-black, homogeneous structureless mass. The nucleus is often eccentric and sometimes lobulated. - ISBN:0721601464 - - - - - acidophilic erythroblast - ISBN:0721601464 - - - - - eosinophilic erythroblast - ISBN:0721601464 - - - - - orthochromatic normoblast - ISBN:0721601464 - - - - - pyknotic eto enrythroblast - ISBN:0721601464 - + @@ -10141,57 +4359,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - The earliest cytologically identifiable precursor in the thrombocytic series. This cell is capable of endomitosis and lacks expression of hematopoieitic lineage markers (lin-negative). - BTO:0001164 - CALOHA:TS-0610 - FMA:84235 - CFU-Meg - Meg-CFC - MkP - colony-forming unit-megakaryocyte - megacaryoblast - megacaryocyte progenitor cell - megakaryoblast - megakaryocytic progenitor cell - cell - promegacaryocyte - promegakaryocyte - Lineage negative is described here as CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD14-negative, CD19-negative, CD20-negative, CD56-negative, Ly6g-negative, and Ter119-negative. - megakaryocyte progenitor cell - - - - - The earliest cytologically identifiable precursor in the thrombocytic series. This cell is capable of endomitosis and lacks expression of hematopoieitic lineage markers (lin-negative). - GOC:dsd - GOC:tfm - ISBN:0721601464 - - - - - CFU-Meg - PMID:11722431 - PMID:12482498 - - - - - Meg-CFC - PMCID:PMC1794060 - - - - - MkP - PMID:21116988 - - - - - megakaryocytic progenitor cell - PMID:12482498 - + @@ -10199,16 +4367,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A peptide hormone secreting cell that secretes gastrin stimulating hormone. - cell - gastrin stimulating hormone secreting cell - - - - A peptide hormone secreting cell that secretes gastrin stimulating hormone. - GOC:tfm - @@ -10216,8 +4375,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - neuronal brush cell @@ -10227,25 +4384,8 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow; mature blood platelets are released from its cytoplasm. - BTO:0000843 - CALOHA:TS-0611 - FMA:83555 - megacaryocyte - megalocaryocyte - megalokaryocyte - cell - Megakaryocytes are reportedly CD181-positive and CD182-positive. - megakaryocyte - - - - - A giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow; mature blood platelets are released from its cytoplasm. - ISBN:0721601464 - MESH:D008533 - http://en.wikipedia.org/wiki/Megakaryocyte - + + @@ -10256,73 +4396,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A hematopoietic progenitor cell that is committed to the granulocyte and monocyte lineages. These cells are CD123-positive, and do not express Gata1 or Gata2 but do express C/EBPa, and Pu.1. - CFU-C , Colony forming unit in culture - CFU-GM - GMP - colony forming unit granulocyte macrophage - granulocyte-macrophage progenitor - granulocyte/monocyte precursor - granulocyte/monocyte progenitor - cell - Originally described in the dendritic cell ontology (DC_CL:0000042)(PMID:19243617). GMPs are reportedly CD16-positive, CD32-positive, CD34-positive, CD38-positive, CD45RA-positive, CD110-negative, CD117-positive, CD123-positive, and SCA1-negative. - granulocyte monocyte progenitor cell - - - - - A hematopoietic progenitor cell that is committed to the granulocyte and monocyte lineages. These cells are CD123-positive, and do not express Gata1 or Gata2 but do express C/EBPa, and Pu.1. - GOC:amm - GOC:dsd - GOC:tfm - GO_REF:0000031 - ISBN:0721601464 - MESH:D055014 - PMCID:PMC2213186 - PMCID:PMC548021 - PMID:16551251 - PMID:16647566 - http://en.wikipedia.org/wiki/CFU-GM - http://www.copewithcytokines.de - - - - - CFU-C , Colony forming unit in culture - http://www.copewithcytokines.de - - - - - CFU-GM - ISBN:0721601464 - PMCID:PMC2213186 - PMCID:PMC548021 - - - - - GMP - ISBN:0721601464 - PMCID:PMC2213186 - PMCID:PMC548021 - - - - - colony forming unit granulocyte macrophage - ISBN:0721601464 - PMCID:PMC2213186 - PMCID:PMC548021 - - - - - granulocyte-macrophage progenitor - ISBN:0721601464 - PMCID:PMC2213186 - PMCID:PMC548021 - + @@ -10330,21 +4404,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds. - BTO:0001173 - CALOHA:TS-0864 - cell - reticulocyte - - - - An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds. - GOC:add - GOC:tfm - PMID:15946868 - PMID:2037622 - @@ -10353,20 +4413,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A precursor in the monocytic series, being a cell intermediate in development between the monoblast and monocyte. This cell is CD11b-positive and has fine azurophil granules. - BTO:0004657 - FMA:83551 - cell - Morphology: Mononuclear cell, diameter 14-18 _M, fine azurophilic granules; markers: CD11b (shared with many other myeloid cells); location: Adult: bone marrow; Fetal: Liver, Yolk Sac; role or process: hematopoiesis, monocyte development; lineage: hematopoietic, myeloid. - promonocyte - - - - A precursor in the monocytic series, being a cell intermediate in development between the monoblast and monocyte. This cell is CD11b-positive and has fine azurophil granules. - GOC:tfm - ISBN:0721601464 - @@ -10374,29 +4421,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A late neutrophilic metamyelocyte in which the nucleus is indented to more than half the distance to the farthest nuclear margin but in no area being condensed to a single filament. The nucleus is in the form of a curved or coiled band, not having acquired the typical multilobar shape of the mature neutrophil. These cells are fMLP receptor-positive, CD11b-positive, CD35-negative, and CD49d-negative. - band - band cell - band form - stab cell - rod neutrophil - cell - Found in the Band 1 fraction. - band form neutrophil - - - - - A late neutrophilic metamyelocyte in which the nucleus is indented to more than half the distance to the farthest nuclear margin but in no area being condensed to a single filament. The nucleus is in the form of a curved or coiled band, not having acquired the typical multilobar shape of the mature neutrophil. These cells are fMLP receptor-positive, CD11b-positive, CD35-negative, and CD49d-negative. - GOC:add - GOC:dsd - GOC:tfm - ISBN:0721601464 - PMID:10618520 - PMID:12560239 - PMID:15514007 - http://www.cap.org - + @@ -10404,22 +4429,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Interneuron of the vertebrate retina. They integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. They lack large axons. - BTO:0004044 - FBbt:00005127 - FMA:67766 - amacrine neuron - cell - Not clear if this term overlaps with retinal bipolar neuron (CL:0000748). - amacrine cell - - - - Interneuron of the vertebrate retina. They integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. They lack large axons. - GOC:tfm - MESH:A08.663.358.050 - @@ -10428,19 +4438,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An erythrocyte having a nucleus. - RBC - red blood cell - cell - nucleate erythrocyte - - - - An erythrocyte having a nucleus. - GOC:add - GOc:tfm - @@ -10448,19 +4446,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A rounded, inactive form that certain bacteria assume under conditions of extreme temperature, dryness, or lack of food. The bacterium develops a waterproof cell wall that protects it from being dried out or damaged. - BTO:0002779 - bacterial spore - cell - endospore - - - - A rounded, inactive form that certain bacteria assume under conditions of extreme temperature, dryness, or lack of food. The bacterium develops a waterproof cell wall that protects it from being dried out or damaged. - GOC:tfm - ISBN:0618947256 - @@ -10469,25 +4455,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A promyelocyte committed to the neutrophil lineage. This cell type is GATA-1-positive, C/EBPa-positive, AML-1-positive, MPO-positive, has low expression of PU.1 transcription factor and lacks lactotransferrin expression. - FMA:84196 - neutrophilic premyelocyte - neutrophilic progranulocyte - cell - These cells are CD11b-negative, CD15-positive, CD16-negative, CD49d-positive, CD68-positive, CD35-negative, and fMLP receptor-negative. They are found in the Band 3 fraction. - neutrophilic promyelocyte - - - - - A promyelocyte committed to the neutrophil lineage. This cell type is GATA-1-positive, C/EBPa-positive, AML-1-positive, MPO-positive, has low expression of PU.1 transcription factor and lacks lactotransferrin expression. - GOC:add - GOC:dsd - GOC:tfm - ISBN:0721601464 - PMID:12560239 - PMID:15514007 - + @@ -10495,16 +4463,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell found in fat bodies whose primary function is intermediary metabolism. - cell - fat body cell - - - - A cell found in fat bodies whose primary function is intermediary metabolism. - FB:ma - @@ -10512,21 +4471,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A mesenchymal stem cell capable of developing into blood vessel endothelium. - angioblast - chondroplast - cell - These cells are reportedly CD31-positive, CD34-positive, CD144-positive, CD309-positive, and TAL1-positive. - angioblastic mesenchymal cell - - - - A mesenchymal stem cell capable of developing into blood vessel endothelium. - GOC:dsd - GOC:tfm - PMID:12768659 - @@ -10534,8 +4479,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - polymodal nocireceptor @@ -10544,21 +4487,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell that originates in the neural crest, that has certain cytochemical and ultrastructural characteristics and is found scattered throughout the body; types include melanocytes, the cells of the chromaffin system, and cells in the hypothalamus, hypophysis, thyroid, parathyroids, lungs, gastrointestinal tract, and pancreas. This cell type concentrates the amino acid precursors of certain amines and decarboxylate them, forming amines that function as regulators and neurotransmitters. This cell type produces substances such as epinephrine, norepinephrine, dopamine, serotonin, enkephalin, somatostatin, neurotensin, and substance P, the actions of which may affect contiguous cells, nearby groups of cells, or distant cells, thus functioning as local or systemic hormones. The name is an acronym for amine precursor uptake and decarboxylation cell. - BTO:0003866 - FMA:83114 - APUD cell - cell - amine precursor uptake and decarboxylation cell - - - - A cell that originates in the neural crest, that has certain cytochemical and ultrastructural characteristics and is found scattered throughout the body; types include melanocytes, the cells of the chromaffin system, and cells in the hypothalamus, hypophysis, thyroid, parathyroids, lungs, gastrointestinal tract, and pancreas. This cell type concentrates the amino acid precursors of certain amines and decarboxylate them, forming amines that function as regulators and neurotransmitters. This cell type produces substances such as epinephrine, norepinephrine, dopamine, serotonin, enkephalin, somatostatin, neurotensin, and substance P, the actions of which may affect contiguous cells, nearby groups of cells, or distant cells, thus functioning as local or systemic hormones. The name is an acronym for amine precursor uptake and decarboxylation cell. - GOC:tfm - ISBN:0721662544 - MESH:A11.070 - @@ -10566,16 +4495,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A mesenchymal cell found in the developing heart and that develops into some part of the heart. These cells derive from intra- and extra-cardiac sources, including the endocardium, epicardium, neural crest, and second heart field. - cell - cardiac mesenchymal cell - - - - A mesenchymal cell found in the developing heart and that develops into some part of the heart. These cells derive from intra- and extra-cardiac sources, including the endocardium, epicardium, neural crest, and second heart field. - PMID:18816864 - @@ -10585,48 +4505,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A neuroepithelial cells that occurs singly or in small groups, close to the outer follicular borders but within the follicular basement membrane of the thyroid. Expresses a form of the neural cell adhesion molecule (N-CAM) on their surface. Secretes calcitonin, 5-hydroxytryptamine and dopamine. - FMA:68653 - SCTID:176770005 - C cell - C cell of thyroid gland - clear cell of thyroid gland - parafollicular cell of thyroid gland - thyroid parafollicular cell - cell - parafollicular cell - - - - - A neuroepithelial cells that occurs singly or in small groups, close to the outer follicular borders but within the follicular basement membrane of the thyroid. Expresses a form of the neural cell adhesion molecule (N-CAM) on their surface. Secretes calcitonin, 5-hydroxytryptamine and dopamine. - GOC:tfm - ISBN:0517223651 - - - - - C cell of thyroid gland - FMA:68653 - - - - - clear cell of thyroid gland - FMA:68653 - - - - - parafollicular cell of thyroid gland - FMA:68653 - - - - - thyroid parafollicular cell - FMA:68653 - + @@ -10634,16 +4513,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A pigment cell derived from the neural crest. Contains uric acid or other purine crystals deposited in stacks called leucosomes. The crystals reflect light and this gives a white appearance under white light. - cell - leucophore - - - - A pigment cell derived from the neural crest. Contains uric acid or other purine crystals deposited in stacks called leucosomes. The crystals reflect light and this gives a white appearance under white light. - SANBI:mhl - @@ -10651,19 +4521,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - One of the two photoreceptor cell types in the vertebrate retina. In cones the photopigment is in invaginations of the cell membrane of the outer segment. Cones are less sensitive to light than rods, but they provide vision with higher spatial and temporal acuity, and the combination of signals from cones with different pigments allows color vision. - BTO:0001036 - CALOHA:TS-0866 - FMA:67748 - cell - retinal cone cell - - - - One of the two photoreceptor cell types in the vertebrate retina. In cones the photopigment is in invaginations of the cell membrane of the outer segment. Cones are less sensitive to light than rods, but they provide vision with higher spatial and temporal acuity, and the combination of signals from cones with different pigments allows color vision. - MESH:A08.663.650.650.670.100 - @@ -10671,16 +4529,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A pigment cell derived from the neural crest. Contains pteridine and/or carotenoid pigments in structures called pterinosomes or erythrosomes. This gives an orange to red appearance. - cell - erythrophore - - - - A pigment cell derived from the neural crest. Contains pteridine and/or carotenoid pigments in structures called pterinosomes or erythrosomes. This gives an orange to red appearance. - SANBI:mhl - @@ -10689,27 +4538,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An epithelial cell of the cornea. - CL:1000431 - BTO:0004298 - CALOHA:TS-0173 - FMA:70551 - epithelial cell of cornea - cell - corneal epithelial cell - - - - - An epithelial cell of the cornea. - GOC:tfm - - - - - epithelial cell of cornea - FMA:70551 - + @@ -10719,21 +4548,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Myeloid mononuclear recirculating leukocyte that can act as a precursor of tissue macrophages, osteoclasts and some populations of tissue dendritic cells. - BTO:0000876 - CALOHA:TS-0638 - FMA:62864 - cell - Morphology: Mononuclear cell, diameter, 14 to 20 _M, N/C ratio 2:1-1:1. Nucleus may appear in variety of shapes: round, kidney, lobulated, or convoluted. Fine azurophilic granules present; markers: CD11b (shared with other myeloid cells), human: CD14, mouse: F4/80-mid,GR1-low; location: Blood, but can be recruited into tissues; role or process: immune & tissue remodelling; lineage: hematopoietic, myeloid. - monocyte - - - - Myeloid mononuclear recirculating leukocyte that can act as a precursor of tissue macrophages, osteoclasts and some populations of tissue dendritic cells. - GO_REF:0000031 - MESH:A11.118.637.555.652 - @@ -10745,23 +4560,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A subtype of enteroendocrine cells found in the gastrointestinal mucosa, particularly in the glands of pyloric antrum; duodenum; and ileum. These cell type secretes serotonin and some neurotransmitters including enkephalins and substance P. Their secretory granules stain readily with silver (argentaffin stain). - CL:0002065 - FMA:62934 - FMA:83132 - Kulchitsky cell - argentaffin cell - enterochromaffin cell - cell - type EC enteroendocrine cell - - - - - A subtype of enteroendocrine cells found in the gastrointestinal mucosa, particularly in the glands of pyloric antrum; duodenum; and ileum. These cell type secretes serotonin and some neurotransmitters including enkephalins and substance P. Their secretory granules stain readily with silver (argentaffin stain). - MESH:A03.492.766.440.250 - PMID:9505449 - + @@ -10769,18 +4568,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell in vitro that has undergone physical changes as a consequence of a deliberate and specific experimental procedure. - cell - This class has been re-labeled to imply reference only to in vitro experimentally modified cells, similarly, the definition has been slightly updated to reflect this. 'experimentally modified cell' refers only to cells in vitro, and not modified in vivo/in environment cells. There is currently no class representing unmodified in vitro cells (other than the parent 'cell in vitro'), or a class representing modified native cells. More granular subclassing of experimentally modified cell can be found in ReO. MHB 1.12.12 - experimentally modified cell in vitro - - - - A cell in vitro that has undergone physical changes as a consequence of a deliberate and specific experimental procedure. - FB:ma - ReO:mhb - @@ -10788,9 +4576,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - FBbt:00004905 - cell - border follicle cell @@ -10801,26 +4586,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A neutrophil precursor in the granulocytic series, being a cell intermediate in development between a promyelocyte and a metamyelocyte; in this stage, production of primary granules is complete and neutrophil-specific granules has started. No nucleolus is present. This cell type is CD13-positive, CD16-negative, integrin alpha-M-positive, CD15-positive, CD33-positive, CD24-positive, C/EBP-a-positive, C/EBPe-positive, PU.1-positive, lactotransferrin-positive, myeloperoxidase-positive and NGAL-positive. - BTO:0003455 - FMA:83540 - cell - These cells are also CD15-positive, CD35-negative, CD49d-positive, and fMLP receptor-negative. They are found in the Band 2 fraction. - neutrophilic myelocyte - - - - - A neutrophil precursor in the granulocytic series, being a cell intermediate in development between a promyelocyte and a metamyelocyte; in this stage, production of primary granules is complete and neutrophil-specific granules has started. No nucleolus is present. This cell type is CD13-positive, CD16-negative, integrin alpha-M-positive, CD15-positive, CD33-positive, CD24-positive, C/EBP-a-positive, C/EBPe-positive, PU.1-positive, lactotransferrin-positive, myeloperoxidase-positive and NGAL-positive. - GOC:add - GOC:dsd - GOC:tfm - ISBN:0721601464 - PMID:10618520 - PMID:12560239 - PMID:15514007 - http://www.cap.org - + @@ -10828,21 +4594,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A macrophage resident in the peritoneum under non-inflammatory conditions. Markers include F4/80-high, CD11b-high, CD68-positive, SIGNR1-positive, CD115-high, MHC-II-negative, and Dectin-1-positive. - BTO:0001034 - FMA:83025 - cell - Markers: Mouse: F4/80-high, CD11b-high, CD68+, SIGNR1+, Dectin-1+. - peritoneal macrophage - - - - A macrophage resident in the peritoneum under non-inflammatory conditions. Markers include F4/80-high, CD11b-high, CD68-positive, SIGNR1-positive, CD115-high, MHC-II-negative, and Dectin-1-positive. - MESH:A11.329.372.630 - PMID:15771589 - PMID:19201820 - @@ -10851,26 +4603,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A neutrophil precursor in the granulocytic series, being a cell intermediate in development between a myelocyte and the band form neutrophil. The protein synthesis seen in earlier stages decreases or stops; the nucleus becomes indented where the indentation is smaller than half the distance to the farthest nuclear margin; chromatin becomes coarse and clumped; specific granules predominate while primary granules are rare; and the cytoplasm becomes amphophilic like that of a mature granulocyte. This cell type is integrin alpha-M-positive, CD13-negative, CD15-positive, CD16-positive, CD33-positive, CD24-positive, fMLP receptor-negative and has expression of C/EBP-a, C/EBP-e, PU.1 transcription factor, lactotransferrin, myeloperoxidase and neutrophil gelatinase associated lipocalin. - FMA:84197 - juvenile neutrophil - cell - These cells are also CD35-negative, CD49d-positive, and fMLP receptor-negative. They are found in the Band 2 fraction. - neutrophilic metamyelocyte - - - - - A neutrophil precursor in the granulocytic series, being a cell intermediate in development between a myelocyte and the band form neutrophil. The protein synthesis seen in earlier stages decreases or stops; the nucleus becomes indented where the indentation is smaller than half the distance to the farthest nuclear margin; chromatin becomes coarse and clumped; specific granules predominate while primary granules are rare; and the cytoplasm becomes amphophilic like that of a mature granulocyte. This cell type is integrin alpha-M-positive, CD13-negative, CD15-positive, CD16-positive, CD33-positive, CD24-positive, fMLP receptor-negative and has expression of C/EBP-a, C/EBP-e, PU.1 transcription factor, lactotransferrin, myeloperoxidase and neutrophil gelatinase associated lipocalin. - GOC:add - GOC:dsd - GOC:tfm - ISBN:0721601464 - PMID:10618520 - PMID:12560239 - PMID:15514007 - http://www.cap.org - + @@ -10878,26 +4611,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A tissue-resident macrophage found in the alveoli of the lungs. Ingests small inhaled particles resulting in degradation and presentation of the antigen to immunocompetent cells. Markers include F4/80-positive, CD11b-/low, CD11c-positive, CD68-positive, sialoadhesin-positive, dectin-1-positive, MR-positive, CX3CR1-negative. - BTO:0000802 - CALOHA:TS-0030 - FMA:83023 - dust cell - cell - MF.Lu - Markers: Mouse: F4/80mid, CD11b-/low, CD11c+, CD68+, sialoadhesin+, dectin-1+, MR+, CX3CR1-. - alveolar macrophage - - - - - A tissue-resident macrophage found in the alveoli of the lungs. Ingests small inhaled particles resulting in degradation and presentation of the antigen to immunocompetent cells. Markers include F4/80-positive, CD11b-/low, CD11c-positive, CD68-positive, sialoadhesin-positive, dectin-1-positive, MR-positive, CX3CR1-negative. - GOC:ana - GOC:dsd - GOC:tfm - GO_REF:0000031 - MESH:A11.329.372.600 - + @@ -10907,30 +4621,13 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An epithelial cell that has its apical plasma membrane folded into microvilli to provide ample surface for the absorption of nutrients from the intestinal lumen. - BTO:0000398 - FMA:62122 - cell - enterocyte - - - - An epithelial cell that has its apical plasma membrane folded into microvilli to provide ample surface for the absorption of nutrients from the intestinal lumen. - SANBI:mhl - - - OBSOLETE: A class of lymphocytes characterized by the lack of surface markers specific for either T or B cells. - cell - This term is rather archaic; consider using 'natural killer cell ; CL:0000623', 'pro-B cell ; CL:0000826', 'pro-T cell ; CL:0000827', or other appropriate lymphocyte-related term depending on the context. - obsolete null cell - true - + @@ -10938,19 +4635,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - The reproductive cell in multicellular organisms. - BTO:0000535 - VHOG:0001534 - WBbt:0006796 - cell - germ cell - - - - The reproductive cell in multicellular organisms. - MESH:A05.360.490 - @@ -10958,16 +4643,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A thermoreceptor cell that detects reduced temperatures. - cell - cold sensing thermoreceptor cell - - - - A thermoreceptor cell that detects reduced temperatures. - GOC:tfm - @@ -10975,19 +4651,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A specialized osteoclast associated with the absorption and removal of cementum. - BTO:0002516 - FMA:83027 - cell - odontoclast - - - - A specialized osteoclast associated with the absorption and removal of cementum. - GOC:add - MESH:A11.329.679 - @@ -10995,19 +4659,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A bulbous cell that is medially placed in one row in the organ of Corti. In contrast to the outer hair cells, the inner hair cells are fewer in number, have fewer sensory hairs, and are less differentiated. - inner hair cell - BTO:0003667 - FMA:62365 - cell - cochlear inner hair cell - - - - A bulbous cell that is medially placed in one row in the organ of Corti. In contrast to the outer hair cells, the inner hair cells are fewer in number, have fewer sensory hairs, and are less differentiated. - MESH:A08.663.650.250.250 - @@ -11015,21 +4667,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A progesterone secreting cell in the corpus luteum that develops from theca cells. - BTO:0002850 - FMA:18690 - small lutein cell - theca lutein cell - cell - small luteal cell - - - - A progesterone secreting cell in the corpus luteum that develops from theca cells. - GOC:tfm - MESH:A05.360.319.114.630.278.400 - @@ -11037,16 +4675,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A thermoreceptor cell that detects reduced temperatures. - cell - warmth sensing thermoreceptor cell - - - - A thermoreceptor cell that detects reduced temperatures. - GOC:tfm - @@ -11055,20 +4684,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A large, progesterone secreting cell in the corpus luteum that develops from the granulosa cells. - FMA:18689 - granulosa lutein cell - cell - granulosoluteocytus - large luteal cell - - - - A large, progesterone secreting cell in the corpus luteum that develops from the granulosa cells. - GOC:tfm - MESH:A05.360.319.114.630.278.400 - @@ -11076,16 +4692,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A steroid hormone secreting cell that secretes androgen. - cell - androgen secreting cell - - - - A steroid hormone secreting cell that secretes androgen. - GOC:tfm - @@ -11094,20 +4701,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An elongated, spindle-shaped, cell that is located between the basal lamina and the plasmalemma of a muscle fiber. These cells are mostly quiescent, but upon activation they divide to produce cells that generate new muscle fibers. - cell - Skeletal muscle satellite cells are not traditionally referred to as myoblasts. They are a heterogeneous population whose division, following activiation, contributes to the formation of skeletal muscle fibers and to maintenance of the skeletal muscle statelite cell population. - skeletal muscle satellite cell - - - - An elongated, spindle-shaped, cell that is located between the basal lamina and the plasmalemma of a muscle fiber. These cells are mostly quiescent, but upon activation they divide to produce cells that generate new muscle fibers. - GOC:tfm - MESH:A11.635.500.700 - PMID:21849021 - PMID:23303905 - @@ -11116,19 +4710,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An erythrocyte lacking a nucleus. - RBC - red blood cell - cell - enucleate erythrocyte - - - - An erythrocyte lacking a nucleus. - GOC:add - GOC:tfm - @@ -11136,20 +4718,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A spore formed following meiosis. Sometimes following meiosis, prospores may undergo one or more rounds of mitosis before they are fully mature. - FAO:0000017 - meiotically-derived spore - cell - sexual spore - - - - A spore formed following meiosis. Sometimes following meiosis, prospores may undergo one or more rounds of mitosis before they are fully mature. - FAO:0000017 - GOC:tfm - SGD:clt - @@ -11157,20 +4726,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - The smaller of two types of asexual spores formed by some fungi. An ovoid to pear-shaped asexual spore that contains very little cytoplasm and organelles, is uninucleate, and forms in vegetative hypae within a mycelium. Micronidia are extruded from the hyphal cell wall. - FAO:0000028 - cell - microconidium - - - - The smaller of two types of asexual spores formed by some fungi. An ovoid to pear-shaped asexual spore that contains very little cytoplasm and organelles, is uninucleate, and forms in vegetative hypae within a mycelium. Micronidia are extruded from the hyphal cell wall. - GOC:tfm - ISBN:0471940526 - PMID:8357339 - SGD:clt - @@ -11178,24 +4734,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Pyramidal neurons have a pyramid-shaped soma with the apex and an apical dendrite pointed toward the pial surface and other dendrites and an axon emerging from the base. The axons may have local collaterals but also project outside their region. Pyramidal neurons are found in the cerebral cortex, the hippocampus, and the amygdala. - BTO:0003102 - FMA:67310 - FMA:86775 - NIFSTD:sao862606388 - projection neuron - pyramidal cell - pyramidal neuron - cell - pyramidal neuron - - - - - Pyramidal neurons have a pyramid-shaped soma with the apex and an apical dendrite pointed toward the pial surface and other dendrites and an axon emerging from the base. The axons may have local collaterals but also project outside their region. Pyramidal neurons are found in the cerebral cortex, the hippocampus, and the amygdala. - GOC:tfm - MESH:A08.186.211.577.405.700 - + @@ -11203,21 +4742,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An asexual, nonmotile spore formed by higher fungi; conidia are usually made from the side or tip of specialized sporogenous cells and do not form by progressive cleavage of the cytoplasm. - BTO:0000283 - FAO:0000024 - cell - conidium - - - - An asexual, nonmotile spore formed by higher fungi; conidia are usually made from the side or tip of specialized sporogenous cells and do not form by progressive cleavage of the cytoplasm. - ISBN:08199377X - PMID:2524423 - PMID:9529886 - SGD:clt - @@ -11226,16 +4751,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A fungal cell with two or more genetically distinct nuclei. - cell - heterokaryon - - - - A fungal cell with two or more genetically distinct nuclei. - ISBN:08199377X - @@ -11243,19 +4759,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A mechanoreceptor in the organ of Corti. In mammals the outer hair cells are arranged in three rows which are further from the modiolus than the single row of inner hair cells. The motile properties of the outer hair cells may contribute actively to tuning the sensitivity and frequency selectivity of the cochlea. - BTO:0003666 - FMA:62366 - cochlear outer hair cell - cell - outer hair cell - - - - A mechanoreceptor in the organ of Corti. In mammals the outer hair cells are arranged in three rows which are further from the modiolus than the single row of inner hair cells. The motile properties of the outer hair cells may contribute actively to tuning the sensitivity and frequency selectivity of the cochlea. - MESH:A08.663.650.250.315 - @@ -11263,16 +4767,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A receptor in the vascular system, particularly the aorta and carotid sinus, which is sensitive to stretch of the vessel walls. - cell - pressoreceptor cell - - - - A receptor in the vascular system, particularly the aorta and carotid sinus, which is sensitive to stretch of the vessel walls. - MESH:A08.800.050.800.900.700 - @@ -11281,16 +4776,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A fungal cell with two genetically distinct haploid nuclei. - cell - dikaryon - - - - A fungal cell with two genetically distinct haploid nuclei. - ISBN:08199377X - @@ -11298,19 +4784,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - One of the two photoreceptor cell types of the vertebrate retina. In rods the photopigment is in stacks of membranous disks separate from the outer cell membrane. Rods are more sensitive to light than cones, but rod mediated vision has less spatial and temporal resolution than cone vision. - BTO:0001024 - CALOHA:TS-0870 - FMA:67747 - cell - retinal rod cell - - - - One of the two photoreceptor cell types of the vertebrate retina. In rods the photopigment is in stacks of membranous disks separate from the outer cell membrane. Rods are more sensitive to light than cones, but rod mediated vision has less spatial and temporal resolution than cone vision. - MESH:A08.663.650.650.670.650 - @@ -11318,20 +4792,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A spore formed following mitosis or mitoses. - FAO:0000023 - cell - fungal asexual spore - - - - A spore formed following mitosis or mitoses. - GOC:tfm - PMID:2524423 - PMID:9529886 - SGD:clt - @@ -11339,19 +4800,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - The larger of two types of asexual spores formed by some fungi; usually round or oblong. - FAO:0000038 - cell - macroconidium - - - - The larger of two types of asexual spores formed by some fungi; usually round or oblong. - GOC:tfm - ISBN:0471940526 - SGD:clt - @@ -11359,20 +4808,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A thick walled spore that stores and protects one or more nuclei following sexual reproduction in an Ascomycete. - BTO:0000097 - FAO:0000020 - cell - ascospore - - - - A thick walled spore that stores and protects one or more nuclei following sexual reproduction in an Ascomycete. - GOC:tfm - ISBN:08199377X - SGD:clt - @@ -11380,19 +4816,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A thick walled, sexual, resting spore formed by Zygomycetes; sometimes refers to the spore and the multi-layered cell wall that encloses the spore, the zygosporangium. - FAO:0000040 - cell - zygospore - - - - A thick walled, sexual, resting spore formed by Zygomycetes; sometimes refers to the spore and the multi-layered cell wall that encloses the spore, the zygosporangium. - ISBN:0471940526 - ISBN:08199377X - SGD:clt - @@ -11400,31 +4824,13 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A mechanoreceptor located in the acoustic maculae and the semicircular canals that mediates the sense of balance, movement, and head position. The vestibular hair cells are connected to accessory structures in such a way that movements of the head displace their stereocilia. This influences the membrane potential of the cells which relay information about movements via the vestibular part of the vestibulocochlear nerve to the brain stem. - FMA:62351 - vestibular receptor cell - cell - vestibular hair cell - - - - A mechanoreceptor located in the acoustic maculae and the semicircular canals that mediates the sense of balance, movement, and head position. The vestibular hair cells are connected to accessory structures in such a way that movements of the head displace their stereocilia. This influences the membrane potential of the cells which relay information about movements via the vestibular part of the vestibulocochlear nerve to the brain stem. - GOC:tfm - MESH:A08.663.650.250.380 - - - PO:0009002 - cell - This term was obsoleted as it is redundant with PO:0009002 in the cell ontology (PO) - obsolete plant cell - true - + @@ -11433,21 +4839,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - EoP - cell - CFU-Eo - colony forming unit eosinophil - eosinophil stem cell - These cells are CD34-positive, CD45RA-negative, CD71-negative, and lineage-negative (CD2, CD3 epsilon, CD4, CD5, CD8a, CD14, CD19, CD20, integrin alpha-M, NCAM-1, SCA-1, Ly6G, Ly76). - eosinophil progenitor cell - - - - EoP - PMCID:PMC2212039 - PMCID:PMC2626675 - @@ -11457,22 +4849,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A eosinophil precursor in the granulocytic series, being a cell intermediate in development between a promyelocyte and a metamyelocyte;in this stage, production of primary granules is complete and eosinophil-specific granules has started. No nucleolus is present. These cells are integrin alpha-M-positive, CD13-positive, CD15-positive, CD16-negative, CD24-positive, and CD33-positive. - BTO:0003454 - FMA:83542 - cell - eosinophilic myelocyte - - - - A eosinophil precursor in the granulocytic series, being a cell intermediate in development between a promyelocyte and a metamyelocyte;in this stage, production of primary granules is complete and eosinophil-specific granules has started. No nucleolus is present. These cells are integrin alpha-M-positive, CD13-positive, CD15-positive, CD16-negative, CD24-positive, and CD33-positive. - GOC:add - GOC:dsd - ISBN:0721601464 - PMID:19622087 - http://www.cap.org - @@ -11481,24 +4858,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A progenitor cell committed to the basophil lineage. This cell lacks hematopoietic lineage markers (lin-negative) and is CD34-positive, T1/ST2-low, CD117-negative, and FceRIa-high. This cell also expresses Gata-1, Gata-2 and C/EBPa. - BaP - cell - CFU-Bas - basophilic stem cell - colony forming unit basophil - BaP are also CD13-low and integrin beta-7-low. They are lin-negative (CD2, CD3e, CD4, CD5, CD8, CD11b, CD14, CD19, CD20, ly6g, ly76, and NCAM-1). They also lack expression of mast cell protease 1 (MCP-1) and microphthalmia-associated transcription factor (mitf). - basophil progenitor cell - - - - - A progenitor cell committed to the basophil lineage. This cell lacks hematopoietic lineage markers (lin-negative) and is CD34-positive, T1/ST2-low, CD117-negative, and FceRIa-high. This cell also expresses Gata-1, Gata-2 and C/EBPa. - GOC:add - GOC:dsd - PMCID:PMC1312421 - http://www.copewithcytokines.de - + @@ -11507,22 +4867,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A basophil precursor in the granulocytic series, being a cell intermediate in development between a promyelocyte and a metamyelocyte; in this stage, production of primary granules is complete and basophil-specific granules has started. No nucleolus is present. Markers are being integrin alpha-M-positive, fucosyltransferase FUT4-positive, CD33-positive, CD24-positive, aminopeptidase N-positive. - BTO:0003456 - FMA:83543 - cell - basophilic myelocyte - - - - A basophil precursor in the granulocytic series, being a cell intermediate in development between a promyelocyte and a metamyelocyte; in this stage, production of primary granules is complete and basophil-specific granules has started. No nucleolus is present. Markers are being integrin alpha-M-positive, fucosyltransferase FUT4-positive, CD33-positive, CD24-positive, aminopeptidase N-positive. - GOC:add - GOC:tfm - ISBN:0721601464 - PMID:18466030 - http://www.cap.org - @@ -11530,37 +4875,13 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A thick walled spore containing one or more haploid nuclei produced by sexual reproduction in an Basidiomycete; formed externally on extrusions of the basidium. - BTO:0002166 - FAO:0000021 - cell - basidiospore - - - - A thick walled spore containing one or more haploid nuclei produced by sexual reproduction in an Basidiomycete; formed externally on extrusions of the basidium. - GOC:clt - ISBN:0471940526 - ISBN:08199377X - - - OBSOLETE: A walled spore produced in a sporangium. - cell - obsolete sporangiospore - true - - - - - OBSOLETE: A walled spore produced in a sporangium. - ISBN:08199377X - + @@ -11569,19 +4890,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A neuron that uses GABA as a vesicular neurotransmitter - FMA:84788 - WBbt:0005190 - GABA-ergic neuron - cell - GABAergic neuron - - - - A neuron that uses GABA as a vesicular neurotransmitter - GOC:tfm - @@ -11589,8 +4898,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - sheath cell @@ -11600,27 +4907,13 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - support cell (sensu Nematoda) - - OBSOLETE: A sporangiospore that is motile, having flagella. - FAO:0000039 - cell - obsolete zoospore - true - - - - - OBSOLETE: A sporangiospore that is motile, having flagella. - ISBN:08199377X - + @@ -11628,16 +4921,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A myoblast that is committed to a myotube-specific program of differentiation but not yet fused. It undergoes very limited additional proliferation. After fusion, it will take on a muscle identity specified by a `muscle founder cell` (CL:0008006). - cell - fusion competent myoblast - - - - A myoblast that is committed to a myotube-specific program of differentiation but not yet fused. It undergoes very limited additional proliferation. After fusion, it will take on a muscle identity specified by a `muscle founder cell` (CL:0008006). - PMID:22274696 - @@ -11646,20 +4930,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A secretory cell that is grouped together with other cells of the same type to form grape shaped clusters known as acini (singular acinus). - FMA:83625 - acinic cell - acinous cell - cell - acinar cell - - - - A secretory cell that is grouped together with other cells of the same type to form grape shaped clusters known as acini (singular acinus). - GOC:tfm - http://www.copewithcytokines.de - @@ -11667,27 +4938,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors and also regulate immune responses via cytokine release and direct contact with other cells. - large granular lymphocyte - null cell - BTO:0000914 - BTO:0004716 - CALOHA:TS-0664 - FMA:63147 - FMA:83601 - VHOG:0001697 - NK cell - cell - natural killer cell - - - - - A lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors and also regulate immune responses via cytokine release and direct contact with other cells. - GOC:add - ISBN:0781735149 - PMID:15771571 - + @@ -11695,20 +4946,8 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A mature alpha-beta T cell that expresses an alpha-beta T cell receptor and the CD4 coreceptor. - CD4-positive, alpha-beta T lymphocyte - CD4-positive, alpha-beta T-cell - CD4-positive, alpha-beta T-lymphocyte - cell - CD4-positive, alpha-beta T cell + - - - - A mature alpha-beta T cell that expresses an alpha-beta T cell receptor and the CD4 coreceptor. - GOC:add - ISBN:0781735149 - @@ -11716,21 +4955,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A T cell expressing an alpha-beta T cell receptor and the CD8 coreceptor. - CD8-positive, alpha-beta T lymphocyte - CD8-positive, alpha-beta T-cell - CD8-positive, alpha-beta T-lymphocyte - cell - CD8-positive, alpha-beta T cell - - - - A T cell expressing an alpha-beta T cell receptor and the CD8 coreceptor. - GOC:add - GOC:tfm - ISBN:0781735149 - @@ -11739,16 +4964,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Granule cell that is part of the olfactory bulb. - cell - olfactory granule cell - - - - Granule cell that is part of the olfactory bulb. - GOC:mah - @@ -11756,16 +4972,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell involved in transporting nutrients, minerals, water, gases and other chemicals between cells for a variety of purposes including conveying nutrition to other tissues, removing waste products from the tissues, conveying gases for respiration, distributing heat and repelling invasion of foreign substances. - cell - transporting cell - - - - A cell involved in transporting nutrients, minerals, water, gases and other chemicals between cells for a variety of purposes including conveying nutrition to other tissues, removing waste products from the tissues, conveying gases for respiration, distributing heat and repelling invasion of foreign substances. - TAIR:sr - @@ -11773,17 +4980,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell that can perform photosynthesis, in which carbohydrates are synthesized from carbon dioxide and water, using light as the energy source. - cell - see PMID:21177950, The making of a photosynthetic animal. - photosynthetic cell - - - - A cell that can perform photosynthesis, in which carbohydrates are synthesized from carbon dioxide and water, using light as the energy source. - TAIR:sr - @@ -11791,16 +4988,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell that is specialized to store a particular substance(s), which is(are) later released from the store for a particular purpose. - cell - storage cell - - - - A cell that is specialized to store a particular substance(s), which is(are) later released from the store for a particular purpose. - FB:ma - @@ -11808,18 +4996,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell whose primary function is to support other cell types. - BTO:0002315 - cell - supportive cell - - - - A cell whose primary function is to support other cell types. - FB:ma - GOC:tfm - @@ -11827,16 +5004,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Cells forming a framework supporting the organ of Corti. Specific cells are those of Claudius, Deiters and Hensen. - cell - labyrinth supporting cell - - - - Cells forming a framework supporting the organ of Corti. Specific cells are those of Claudius, Deiters and Hensen. - MESH:A09.246.631.246.577.543 - @@ -11846,38 +5014,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell that is found in the perisinusoidal space of the liver that is capable of multiple roles including storage of retinol, presentation of antigen to T cells (including CD1d-restricted NKT cells), and upon activation, production of extracellular matrix components that can contribute to liver fibrosis. This activated state has a myofibroblast-like phenotype, though it's not clear in the literature if this is terminally differentiated. This cell type comprises approximately 8-15% of total cells in the liver. - BTO:0002741 - CALOHA:TS-0452 - FMA:67763 - Ito cell - hepatic perisinusoidal cell - perisinusoidal cell - cell - fat-storing cell - lipocyte - vitamin A-storing cells - Hepatic stellate cells are CD271-positive, desmin-positive, DDR-2-positive, GFAP-positive, synamin-positive, synaptophysin-positive, vimentin-positive, They are capable of producing angiotensin II, fibronectin, laminin, MMP-1, MMP-2, MMP-3, MMP-9, MMP-11, TGF-beta1, TIMP-1, TIMP-2, type I collagen, type III collagen, type IV collagen, and type VI collagen. - hepatic stellate cell - - - - - A cell that is found in the perisinusoidal space of the liver that is capable of multiple roles including storage of retinol, presentation of antigen to T cells (including CD1d-restricted NKT cells), and upon activation, production of extracellular matrix components that can contribute to liver fibrosis. This activated state has a myofibroblast-like phenotype, though it's not clear in the literature if this is terminally differentiated. This cell type comprises approximately 8-15% of total cells in the liver. - GOC:dsd - MESH:D055166 - PMID:12808230 - PMID:17239632 - PMID:18222966 - PMID:9302568 - http://en.wikipedia.org/wiki/Hepatic_stellate_cell - - - - - vitamin A-storing cells - PMID:12808230 - + @@ -11885,21 +5022,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A tall supporting cell that is arranged in rows adjacent to the last row of outer phalangeal cells. This cell type constitutes the outer border of the organ of Corti. - FMA:79799 - Hensen's cell - cell of Hensen - external limiting cell of organ of Corti - cell - Hensen cell - - - - A tall supporting cell that is arranged in rows adjacent to the last row of outer phalangeal cells. This cell type constitutes the outer border of the organ of Corti. - GOC:tfm - ISBN:0721662544 - @@ -11907,21 +5030,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cuboidal cell which along with Boettcher's cells form the floor of the external spiral sulcus, external to the organ of Corti. - FMA:79802 - cell of Claudius - external supporting cell of vestibular epithelium - cell - external supporting cell of Claudius - Claudius cell - - - - A cuboidal cell which along with Boettcher's cells form the floor of the external spiral sulcus, external to the organ of Corti. - GOC:tfm - ISBN:0721662544 - @@ -11929,21 +5038,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - The outer phalangeal cells of the organ of Corti. This cell holds the base of the hair cell in a cup-shaped depression. - FMA:75725 - Deiters cell - outer phalangeal cell - cell - Deiter's cell - - - - The outer phalangeal cells of the organ of Corti. This cell holds the base of the hair cell in a cup-shaped depression. - GOC:tfm - ISBN:0721662544 - http://www.britannica.com/EBchecked/topic/156177/Deiters-cell - @@ -11951,9 +5046,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - BTO:0003064 - cell - Mueller cell @@ -11964,19 +5056,9 @@ Covers cells actively being cultured or stored in a quiescent state for future u + - A cell that stains readily in the anterior pituitary gland. - FMA:83089 - cell - chromophil cell of anterior pituitary gland - - - - A cell that stains readily in the anterior pituitary gland. - GOC:tfm - ISBN:0618947256 - @@ -11984,21 +5066,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An acidophilic chromophil cell that of the anterior pituitary gland. - FMA:83093 - acidophil cell of pars anterior of adenohypophysis - acidophil of pars anterior of adenohypophysis - acidophil of pars distalis of adenohypophysis - pituitary alpha cell - cell - acidophil cell of pars distalis of adenohypophysis - - - - An acidophilic chromophil cell that of the anterior pituitary gland. - GOC:tfm - @@ -12006,20 +5074,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A basophillic chromophil cell that of the anterior pituitary gland. - FMA:83094 - basophil cell of anterior lobe of hypophysis - cell - beta cell - pituitary beta cell - basophil cell of pars distalis of adenohypophysis - - - - A basophillic chromophil cell that of the anterior pituitary gland. - GOC:tfm - @@ -12027,18 +5082,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell that is resistant to stains. - FMA:83626 - chromophobic cell - cell - chromophobe cell - - - - A cell that is resistant to stains. - GOC:tfm - @@ -12047,16 +5091,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A supportive cell of the vertebrate pituitary that provides macromolecular transport and secretes hormones. - cell - folliculostellate cell - - - - A supportive cell of the vertebrate pituitary that provides macromolecular transport and secretes hormones. - JB:jb - @@ -12064,20 +5099,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Type of radial astrocyte in the cerebellar cortex that have their cell bodies in the Purkinje cell layer and processes that extend into the molecular layer, terminating with bulbous endfeet at the pial surface. Bergmann glia express high densities of glutamate transporters that limit diffusion of the neurotransmitter glutamate during its release from synaptic terminals. Besides their role in early development of the cerebellum, Bergmann glia are also required for the pruning or addition of synapses. - FMA:54559 - Bergmann astrocyte - Bergmann glial cell of cerebellum - cell - Bergmann glial cell - - - - Type of radial astrocyte in the cerebellar cortex that have their cell bodies in the Purkinje cell layer and processes that extend into the molecular layer, terminating with bulbous endfeet at the pial surface. Bergmann glia express high densities of glutamate transporters that limit diffusion of the neurotransmitter glutamate during its release from synaptic terminals. Besides their role in early development of the cerebellum, Bergmann glia are also required for the pruning or addition of synapses. - GOC:tfm - http://www.neurolex.org/wiki/Category:Bergmann_Glial_Cell - @@ -12085,20 +5107,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell with long processes running parallel to adjacent axons in the proximal infundibulum of the neurohypophysis. These processes form a three-dimensional network among the axons of the hypothalamic neurosecretory cells and are connected by gap junctions which provide for their metabolic coupling. This cell type constitutes most of the nonexcitable tissue in the neurohypophsis; function may include possibly acting as an intermediate in the modulation of oxytocin and vasopressin release. This cell type is highly variable in size and shape and commonly contain lipid droplets and deposits of lipochrome pigment. - BTO:0003793 - FMA:83503 - cell - pituicyte - - - - A cell with long processes running parallel to adjacent axons in the proximal infundibulum of the neurohypophysis. These processes form a three-dimensional network among the axons of the hypothalamic neurosecretory cells and are connected by gap junctions which provide for their metabolic coupling. This cell type constitutes most of the nonexcitable tissue in the neurohypophsis; function may include possibly acting as an intermediate in the modulation of oxytocin and vasopressin release. This cell type is highly variable in size and shape and commonly contain lipid droplets and deposits of lipochrome pigment. - ISBN:0412046911 - ISBN:0517223651 - http://en.wikipedia.org/wiki/Pituicyte - @@ -12106,19 +5115,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Undifferentiated; mitotic stem cell for other epithelial cell types; rounded or elliptical with little cytoplasm and few organelles; contain cytokeratin intermediate filament. - BTO:0000939 - FMA:62516 - cell - basal cell - - - - Undifferentiated; mitotic stem cell for other epithelial cell types; rounded or elliptical with little cytoplasm and few organelles; contain cytokeratin intermediate filament. - GOC:tfm - ISBN:0517223651 - @@ -12127,62 +5124,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A phagocytic cell formed by the fusion of macrophages, occurs in chronic inflammatory responses to persistent microorganism such as M.tuberculosis, component of granulomas. Sometimes used to refer to megakaryocytes. - BTO:0003107 - FMA:83035 - Langerhans giant cell - foreign body giant cell - macrophage polykaryon - multinucleate giant cell - syncytial giant cell - cell - Role or process: Chronic infection, granulomatous inflammation. Consider also megakaryocyte (CL:0000556) as sometimes multinucleated giant cell is used to refer to this. - multinucleated giant cell - - - - - A phagocytic cell formed by the fusion of macrophages, occurs in chronic inflammatory responses to persistent microorganism such as M.tuberculosis, component of granulomas. Sometimes used to refer to megakaryocytes. - GOC:add - GOC:tfm - ISBN:0702022918 - ISBN:0702024783 - - - - - Langerhans giant cell - ISBN:0702022918 - ISBN:0702024783 - - - - - foreign body giant cell - ISBN:0702022918 - ISBN:0702024783 - - - - - macrophage polykaryon - ISBN:0702022918 - ISBN:0702024783 - - - - - multinucleate giant cell - ISBN:0702022918 - ISBN:0702024783 - - - - - syncytial giant cell - ISBN:0702022918 - ISBN:0702024783 - + @@ -12192,23 +5134,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A smooth muscle cell that synthesizes, stores, and secretes the enzyme renin. This cell type are located in the wall of the afferent arteriole at the entrance to the glomerulus. While having a different origin than other kidney smooth muscle cells, this cell type expresses smooth muscle actin upon maturation. - CL:0000461 - juxtaglomerular cell - FMA:84138 - JG cell - renin secreting cell - cell - kidney granular cell - - - - - A smooth muscle cell that synthesizes, stores, and secretes the enzyme renin. This cell type are located in the wall of the afferent arteriole at the entrance to the glomerulus. While having a different origin than other kidney smooth muscle cells, this cell type expresses smooth muscle actin upon maturation. - GOC:cvs - GOC:tfm - PMID:11457727 - + @@ -12216,21 +5142,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell with delicate radiating processes known as desmosomes that form intercellular bridges between other cells of this type. This cell type forms the stratum spinosum (prickle cell layer). A function of this cell is to generate keratin. - CL:0002186 - FMA:69059 - prickle cell of epidermis - cell - prickle cell - - - - A cell with delicate radiating processes known as desmosomes that form intercellular bridges between other cells of this type. This cell type forms the stratum spinosum (prickle cell layer). A function of this cell is to generate keratin. - GOC:tfm - ISBN:0721662544 - ISBN:0815332181 - @@ -12238,22 +5150,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell type that encapsulates the capillaries and venules in the kidney. This cell secretes mesangial matrix that provides the structural support for the capillaries. - BTO:0000853 - CALOHA:TS-0617 - FMA:70972 - kidney mesangial cell - cell - Do all of these cells really develop from some mesenchymal stem cell? - mesangial cell - - - - A cell type that encapsulates the capillaries and venules in the kidney. This cell secretes mesangial matrix that provides the structural support for the capillaries. - GOC:tfm - http://www.copewithcytokines.de/cope.cgi?key=mesangial%20cells - @@ -12262,17 +5159,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A mucus-secreting cell, with numerous apical secretory vesicles containing mucins; nucleus are basally displaced; numerous at the neck of mucus secreting glands - neck cell - cell - mucous neck cell - - - - A mucus-secreting cell, with numerous apical secretory vesicles containing mucins; nucleus are basally displaced; numerous at the neck of mucus secreting glands - GOC:tfm - @@ -12282,21 +5169,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - This cell type produces and secretes melatonin and forms the pineal parenchyma. Extending from each cell body, which has a spherical, oval or lobulated mucleus, are one or more tortuous basophilic processes, containing parallel microtubules known as synaptic ribbons. These processes end in expanded terminal buds near capillaries or less, frequently, ependymal cells of the pineal recess. The terminal buds contain granular endoplasmic reticulum, mitochondria and electron-dense cored vesicles, which store monoamines and polypeptide hormones, release of which appears to require sympathetic innervation. - BTO:0001068 - FMA:83417 - cell - pinealocyte - - - - This cell type produces and secretes melatonin and forms the pineal parenchyma. Extending from each cell body, which has a spherical, oval or lobulated mucleus, are one or more tortuous basophilic processes, containing parallel microtubules known as synaptic ribbons. These processes end in expanded terminal buds near capillaries or less, frequently, ependymal cells of the pineal recess. The terminal buds contain granular endoplasmic reticulum, mitochondria and electron-dense cored vesicles, which store monoamines and polypeptide hormones, release of which appears to require sympathetic innervation. - GOC:tfm - ISBN:0517223651 - PMID:16687276 - http://en.wikipedia.org/wiki/Pinealocyte - @@ -12305,33 +5178,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A glomerular visceral epithelial cell is a specialized kidney epithelial cell that contains "feet" that interdigitate with the "feet" of other glomerular epithelial cells. - epithelial cell of visceral layer of glomerular capsule - BTO:0002295 - glomerular podocyte - podocyte - cell - GO has podocyte as a related synonym due to concern this may refer to more than one cell type. However, this did not turn up in my search. If podocyte does refer to more than one cell type, then we should classify the synonym to 'related'[tfm]. - glomerular visceral epithelial cell - - - - - A glomerular visceral epithelial cell is a specialized kidney epithelial cell that contains "feet" that interdigitate with the "feet" of other glomerular epithelial cells. - GOC:tfm - - - - - epithelial cell of visceral layer of glomerular capsule - FMA:70967 - - - - - glomerular podocyte - FMA:70967 - + @@ -12339,20 +5186,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A primary oocyte is an oocyte that has not completed female meosis I. - BTO:0000512 - FMA:18645 - cell - primary oogonium - primary oocyte - - - - A primary oocyte is an oocyte that has not completed female meosis I. - GOC:tfm - ISBN:0721662544 - @@ -12360,20 +5194,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A secondary oocyte is an oocyte that has not completed meiosis II. - BTO:0003094 - FMA:18646 - cell - primary oogonium - secondary oocyte - - - - A secondary oocyte is an oocyte that has not completed meiosis II. - GOC:tfm - ISBN:0721662544 - @@ -12381,20 +5202,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A diploid cell that has derived from a spermatogonium and can subsequently begin meiosis and divide into two haploid secondary spermatocytes. - BTO:0001115 - CALOHA:TS-2194 - FMA:72292 - cell - primary spermatocyte - - - - A diploid cell that has derived from a spermatogonium and can subsequently begin meiosis and divide into two haploid secondary spermatocytes. - GOC:tfm - ISBN:0721662544 - @@ -12403,21 +5211,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - One of the two haploid cells into which a primary spermatocyte divides, and which in turn gives origin to spermatids. - BTO:0000709 - CALOHA:TS-2195 - FBbt:00004941 - FMA:72293 - cell - secondary spermatocyte - - - - One of the two haploid cells into which a primary spermatocyte divides, and which in turn gives origin to spermatids. - GOC:tfm - ISBN:0721662544 - @@ -12426,16 +5220,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An epithelial cell that secretes cuticle. - cell - cuticle secreting cell - - - - An epithelial cell that secretes cuticle. - GOC:tfm - @@ -12444,16 +5229,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An extracellular matrix secreting cell that secretes eggshell. - cell - eggshell secreting cell - - - - An extracellular matrix secreting cell that secretes eggshell. - GOC:tfm - @@ -12461,16 +5237,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An extracellular matrix secreting cell that secretes glycocalyx. - cell - glycocalyx secreting cell - - - - An extracellular matrix secreting cell that secretes glycocalyx. - GOC:tfm - @@ -12478,8 +5245,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - distal tip cell (sensu Nematoda) @@ -12488,8 +5253,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - neuroglioblast (sensu Nematoda) @@ -12498,8 +5261,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - valve cell @@ -12509,8 +5270,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - closable valve cell @@ -12519,8 +5278,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - permanently open valve cell @@ -12530,9 +5287,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - window cell - cell - fenestrated cell @@ -12541,36 +5295,13 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An extracellular matrix secreting cell that secretes collagen. - cell - collagen secreting cell - - - - An extracellular matrix secreting cell that secretes collagen. - GOC:tfm - - - OBSOLETE: The cell characteristic of an organ, as distinguished from associated connective or supporting tissues. - BTO:0002174 - FMA:84638 - cell - OBSOLETE: Term was made obsolete to avoid confusion with plant parenchymal cell. Cell type has a similar but slightly different meaning in botany (plants): see PO:0000074. - obsolete parenchymal cell - true - - - - - OBSOLETE: The cell characteristic of an organ, as distinguished from associated connective or supporting tissues. - ISBN:0471245208 - + @@ -12580,38 +5311,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An elongated, contractile cell found wrapped about precapillary arterioles outside the basement membrane. Pericytes are present in capillaries where proper adventitia and muscle layer are missing (thus distingushing this cell type from adventitial cells). They are relatively undifferentiated and may become fibroblasts, macrophages, or smooth muscle cells. - CL:0000184 - BTO:0002441 - FMA:63174 - ARC - adventitial reticular cell - cell of Rouget - pericyte - pericyte of Rouget - cell - adventitial cell - Pericytes are CD10-positive, CD13-positive, CD31-negative, CD45-negative, CD106-positive, CD117-negative, CD140-positive, CD144-negative, CD146-positive, CD271-positive, CD325-positive, NG2-positive, RGS5-positive, SMA-positive, and desmin-positive. A subpopulation is CD248-positive. They are also capable of producing angiopoietin 1, CXCL12, TGF-beta, and VEGF-A. - pericyte cell - - - - - An elongated, contractile cell found wrapped about precapillary arterioles outside the basement membrane. Pericytes are present in capillaries where proper adventitia and muscle layer are missing (thus distingushing this cell type from adventitial cells). They are relatively undifferentiated and may become fibroblasts, macrophages, or smooth muscle cells. - GOC:dsd - GOC:tfm - ISBN:0721662544 - MESH:D020286 - PMID:16807374 - PMID:17986482 - PMID:20024907 - - - - - ARC - PMID:17986482 - + @@ -12620,20 +5320,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A primordial germ cell is a diploid germ cell precursors that transiently exist in the embryo before they enter into close association with the somatic cells of the gonad and become irreversibly committed as germ cells. - FMA:70567 - gonocyte - primitive germ cell - cell - primordial germ cell - - - - A primordial germ cell is a diploid germ cell precursors that transiently exist in the embryo before they enter into close association with the somatic cells of the gonad and become irreversibly committed as germ cells. - GOC:tfm - PMID:1381289 - @@ -12641,28 +5328,13 @@ Covers cells actively being cultured or stored in a quiescent state for future u - FBbt:00004906 - cell - centripetally migrating follicle cell - - Obsolete. Use PO:0000290 from Plant Ontology instead. A water conducting cell, tracheid or vessel member. - cell - replaced_by: PO:0000290 - obsolete tracheary element - true - - - - - Obsolete. Use PO:0000290 from Plant Ontology instead. A water conducting cell, tracheid or vessel member. - ISBN:0471245208 - + @@ -12670,8 +5342,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - Kenyon cell @@ -12680,10 +5350,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - FBbt:00004910 - fly stalk cell - cell - interfollicle cell @@ -12693,16 +5359,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A mature sexual reproductive cell of the female germline. - cell - female gamete - - - - A mature sexual reproductive cell of the female germline. - GOC:tfm - @@ -12710,9 +5367,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - BTO:0001033 - cell - cap cell @@ -12721,16 +5375,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Cell of the intestinal epithelium with a brush border made up of many parallel packed microvilli; associated with absorption, particularly of macromolecules. - cell - gut absorptive cell - - - - Cell of the intestinal epithelium with a brush border made up of many parallel packed microvilli; associated with absorption, particularly of macromolecules. - JB:jb - @@ -12738,8 +5383,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - commissural neuron @@ -12749,9 +5392,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - WBbt:0006829 - cell - glutamatergic neuron @@ -12761,16 +5401,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A non-terminally differentiated cell that is capable of developing into a muscle cell. - cell - muscle precursor cell - - - - A non-terminally differentiated cell that is capable of developing into a muscle cell. - GOC:add - @@ -12778,19 +5409,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell present in the developing CNS. Functions as both a precursor cell and as a scaffold to support neuronal migration. - forebrain radial glial cell - cell - Unlike that of mammals, the brain of adult teleost fish exhibits an intense and widespread neurogenic activity as a result of the persistence of -radial glial cells acting as neural progenitors throughout life. - radial glial cell - - - - A cell present in the developing CNS. Functions as both a precursor cell and as a scaffold to support neuronal migration. - GOC:dph - @@ -12800,23 +5419,7 @@ radial glial cells acting as neural progenitors throughout life. - An absorptive cell of the gut epithelium that endocytoses microorganisms and intact macromolecules from the gut lumen and transports them to the subepithelial space where they are presented to antigen-presenting cells and lymphocytes. - M cell - BTO:0003600 - FMA:62929 - M-cell - microfold cell - cell - Should double check and see if M cells are particular to a specific region. - M cell of gut - - - - - An absorptive cell of the gut epithelium that endocytoses microorganisms and intact macromolecules from the gut lumen and transports them to the subepithelial space where they are presented to antigen-presenting cells and lymphocytes. - GOC:jb - GOC:tfm - + @@ -12824,18 +5427,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell that transports hormones from neurosecretory cells. This nerve cell is characterized by bipolar shape and endfeet that contact a basal lamina around blood vessels, and/or the pia mater or vitreous body of the eye and additionally contact the ventricular surface or sub-retinal space. - ependymal astrocyte - cell - ependymoglial cell - - - - A cell that transports hormones from neurosecretory cells. This nerve cell is characterized by bipolar shape and endfeet that contact a basal lamina around blood vessels, and/or the pia mater or vitreous body of the eye and additionally contact the ventricular surface or sub-retinal space. - JB:jb - http://neurolex.org/wiki/Category:Ependymoglial_Cell - @@ -12843,27 +5435,13 @@ radial glial cells acting as neural progenitors throughout life. - cell - littoral cell of liver - - Obsolete. Use PO:0004010 from Plant Ontology instead. A cell synthesizing protoplasm and producing new cells by division and with only a primary cell wall. - cell - replaced_by: PO:0004010 - obsolete meristematic cell - true - - - - - Obsolete. Use PO:0004010 from Plant Ontology instead. A cell synthesizing protoplasm and producing new cells by division and with only a primary cell wall. - PO:0004010 - + @@ -12872,16 +5450,7 @@ radial glial cells acting as neural progenitors throughout life. - A columnar/cuboidal epithelial cell that secretes cerebrospinal fluid. - cell - cerebrospinal fluid secreting cell - - - - A columnar/cuboidal epithelial cell that secretes cerebrospinal fluid. - GOC:tfm - @@ -12890,9 +5459,6 @@ radial glial cells acting as neural progenitors throughout life. - R1 cell - cell - R1 photoreceptor cell @@ -12902,16 +5468,7 @@ radial glial cells acting as neural progenitors throughout life. - A fibroblast-like cell that provides support at neuromuscular junctions in vertebrates and are localized outside the synaptic basal lamina. - cell - perijunctional fibroblast - - - - A fibroblast-like cell that provides support at neuromuscular junctions in vertebrates and are localized outside the synaptic basal lamina. - JB:jb - @@ -12919,16 +5476,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell with both myofibrils and secretory granules. - cell - myoendocrine cell - - - - A cell with both myofibrils and secretory granules. - JB:jb - @@ -12937,9 +5485,6 @@ radial glial cells acting as neural progenitors throughout life. - R2 cell - cell - R2 photoreceptor cell @@ -12948,8 +5493,6 @@ radial glial cells acting as neural progenitors throughout life. - cell - stellate interneuron @@ -12959,18 +5502,7 @@ radial glial cells acting as neural progenitors throughout life. - A neuroglial cell of the peripheral nervous system inside the basal lamina of the neuromuscular junction providing chemical and physical support to the synapse. - Schwann cell - cell - terminal Schwann cell - - - - A neuroglial cell of the peripheral nervous system inside the basal lamina of the neuromuscular junction providing chemical and physical support to the synapse. - JB:jb - PMID:16136171 - @@ -12978,17 +5510,7 @@ radial glial cells acting as neural progenitors throughout life. - A stellate interneuron having 7-10 dendrites that may branch. - spiderweb cell - cell - neuroglioform cell - - - - A stellate interneuron having 7-10 dendrites that may branch. - JB:jb - @@ -12997,9 +5519,6 @@ radial glial cells acting as neural progenitors throughout life. - R3 cell - cell - R3 photoreceptor cell @@ -13008,17 +5527,7 @@ radial glial cells acting as neural progenitors throughout life. - One of a transient population of pioneering neurons in the cerebral cortex. These cells are slender bipolar cells of the developing marginal zone. One feature of these cells in mammals is that they express the Reelin gene. - cell - Cajal-Retzius cell - - - - One of a transient population of pioneering neurons in the cerebral cortex. These cells are slender bipolar cells of the developing marginal zone. One feature of these cells in mammals is that they express the Reelin gene. - PMID:10600995 - PMID:9728912 - @@ -13027,21 +5536,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell that stores and secretes pancreatic polypeptide hormone. - FMA:62938 - FMA:83409 - type F enteroendocrine cell - cell - PP cell - - - - A cell that stores and secretes pancreatic polypeptide hormone. - GOC:tfm - JB:jb - PMID:15153415 - @@ -13050,20 +5545,13 @@ radial glial cells acting as neural progenitors throughout life. - R4 cell - cell - R4 photoreceptor cell - - cell - obsolete paraganglial cell - true - + @@ -13071,16 +5559,7 @@ radial glial cells acting as neural progenitors throughout life. - A type of glomus or chief cell, is sensitive to hypoxia and produce catecholamines. - cell - paraganglial type 1 cell - - - - A type of glomus or chief cell, is sensitive to hypoxia and produce catecholamines. - GOC:tfm - @@ -13089,20 +5568,7 @@ radial glial cells acting as neural progenitors throughout life. - A neuron that releases dopamine as a neurotransmitter. - BTO:0004032 - FMA:84787 - WBbt:0006746 - dopaminergic cell - cell - dopaminergic neuron - - - - A neuron that releases dopamine as a neurotransmitter. - GOC:dhill - @@ -13110,16 +5576,7 @@ radial glial cells acting as neural progenitors throughout life. - Supports paraganglial type 1 cell. - cell - paraganglia type 2 cell - - - - Supports paraganglial type 1 cell. - JB:jb - @@ -13128,9 +5585,6 @@ radial glial cells acting as neural progenitors throughout life. - R5 cell - cell - R5 photoreceptor cell @@ -13139,17 +5593,7 @@ radial glial cells acting as neural progenitors throughout life. - Cell that provides some or all mechanical, nutritional and phagocytic support to their neighbors. - BTO:0002315 - cell - sustentacular cell - - - - Cell that provides some or all mechanical, nutritional and phagocytic support to their neighbors. - JB:jb - @@ -13157,16 +5601,7 @@ radial glial cells acting as neural progenitors throughout life. - A specialized endothelial cell that senses extracellular signals and guides the directed growth of blood vessels. - cell - endothelial tip cell - - - - A specialized endothelial cell that senses extracellular signals and guides the directed growth of blood vessels. - PMID:15376331 - @@ -13175,9 +5610,6 @@ radial glial cells acting as neural progenitors throughout life. - R6 cell - cell - R6 photoreceptor cell @@ -13188,22 +5620,7 @@ radial glial cells acting as neural progenitors throughout life. - Specialized ependymal cell that produces the cerebrospinal fluid from the blood and secretes it into the lumen of the brain and spinal chord. - CL:1000430 - FMA:70549 - epithelial cell of choroid plexus - cell - choroid plexus epithelial cell - - - - Specialized ependymal cell that produces the cerebrospinal fluid from the blood and secretes it into the lumen of the brain and spinal chord. - GOC:add - GOC:tfm - JB:jb - PMID:9550134 - @@ -13212,9 +5629,6 @@ radial glial cells acting as neural progenitors throughout life. - R7 cell - cell - R7 photoreceptor cell @@ -13224,17 +5638,7 @@ radial glial cells acting as neural progenitors throughout life. - Stromal cell that forms the internal covering of the vertebrate brain and produces ECM for this and the choroid plexus. - cell - leptomemingeal cell - leptomeningeal cell - - - - Stromal cell that forms the internal covering of the vertebrate brain and produces ECM for this and the choroid plexus. - JB:jb - @@ -13243,9 +5647,6 @@ radial glial cells acting as neural progenitors throughout life. - R8 cell - cell - R8 photoreceptor cell @@ -13255,20 +5656,7 @@ radial glial cells acting as neural progenitors throughout life. - Epithelial cells derived from neural plate and neural crest. - neuroepithelial cell - BTO:0004301 - FMA:70557 - cell - The term "neuroepithelial cell" is used to describe both this cell type and sensory epithelial cell (CL:0000098). - neurecto-epithelial cell - - - - Epithelial cells derived from neural plate and neural crest. - GOC:tfm - @@ -13277,18 +5665,7 @@ radial glial cells acting as neural progenitors throughout life. - Cumulus cell is a specialized granulosa cell that surrounds and nourishes the oocyte. This cell-type surrounds the fully-grown oocyte to form a cumulus-oocyte complex (abbr. COC). The terms cumulus oophorus cells, cumulus granulosa cells, cumulus oophorous granulosa cells, granulosa-cumulus cells are used to make a distinction between this cell and the other functionally different subpopulation of granulosa cells at the wall of the Graafian follicle. - BTO:0002236 - cell - cumulus cell - - - - Cumulus cell is a specialized granulosa cell that surrounds and nourishes the oocyte. This cell-type surrounds the fully-grown oocyte to form a cumulus-oocyte complex (abbr. COC). The terms cumulus oophorus cells, cumulus granulosa cells, cumulus oophorous granulosa cells, granulosa-cumulus cells are used to make a distinction between this cell and the other functionally different subpopulation of granulosa cells at the wall of the Graafian follicle. - GOC:tfm - http://www.copewithcytokines.org/cope.cgi?key=cumulus%20cells - @@ -13296,8 +5673,6 @@ radial glial cells acting as neural progenitors throughout life. - cell - stratum granulosum cell @@ -13306,8 +5681,6 @@ radial glial cells acting as neural progenitors throughout life. - cell - corona radiata cell @@ -13317,8 +5690,6 @@ radial glial cells acting as neural progenitors throughout life. - cell - embryonic crystal cell @@ -13328,8 +5699,6 @@ radial glial cells acting as neural progenitors throughout life. - cell - lymph gland crystal cell @@ -13338,16 +5707,7 @@ radial glial cells acting as neural progenitors throughout life. - A subset of motor neurons that innervates intrafusal muscle fibers and has small diameter axons. - cell - fusimotor neuron - - - - A subset of motor neurons that innervates intrafusal muscle fibers and has small diameter axons. - PMID:15582775 - @@ -13355,9 +5715,6 @@ radial glial cells acting as neural progenitors throughout life. - cell - cone cell (sensu Endopterygota) - compound eye cone cell @@ -13366,8 +5723,6 @@ radial glial cells acting as neural progenitors throughout life. - cell - posterior cone cell (sensu Endopterygota) @@ -13376,8 +5731,6 @@ radial glial cells acting as neural progenitors throughout life. - cell - anterior cone cell (sensu Endopterygota) @@ -13386,8 +5739,6 @@ radial glial cells acting as neural progenitors throughout life. - cell - equatorial cone cell (sensu Endopterygota) @@ -13396,8 +5747,6 @@ radial glial cells acting as neural progenitors throughout life. - cell - cystoblast @@ -13407,18 +5756,7 @@ radial glial cells acting as neural progenitors throughout life. - A stem cell that can give rise to cell types of the body other than those of the germ-line. - CALOHA:TS-2086 - FMA:63368 - cell - somatic stem cell - - - - A stem cell that can give rise to cell types of the body other than those of the germ-line. - GO:0048103 - @@ -13427,17 +5765,7 @@ radial glial cells acting as neural progenitors throughout life. - A differentiated cell that functions as a site of nitrogen fixation under aerobic conditions. - BTO:0000600 - cell - heterocyst - - - - A differentiated cell that functions as a site of nitrogen fixation under aerobic conditions. - MA:ma - @@ -13445,8 +5773,6 @@ radial glial cells acting as neural progenitors throughout life. - cell - nitrogen fixing cell @@ -13455,18 +5781,7 @@ radial glial cells acting as neural progenitors throughout life. - An asexual 1-celled spore (primarily for perennation, not dissemination). Originates endogenously and singly within part of a pre-existing cell by the contraction of the protoplast. Possesses an inner secondary and often thickened hyaline or brown wall, usually impregnated with hydrophobic material. - cell - Considering obsoleting as sometimes used to refer to protozoans too. But reference indicates term was intended for fungus. - chlamydospore - - - - An asexual 1-celled spore (primarily for perennation, not dissemination). Originates endogenously and singly within part of a pre-existing cell by the contraction of the protoplast. Possesses an inner secondary and often thickened hyaline or brown wall, usually impregnated with hydrophobic material. - GOC:tfm - ISBN:085199377X - @@ -13474,8 +5789,6 @@ radial glial cells acting as neural progenitors throughout life. - cell - primary pigment cell @@ -13484,8 +5797,6 @@ radial glial cells acting as neural progenitors throughout life. - cell - secondary pigment cell @@ -13494,8 +5805,6 @@ radial glial cells acting as neural progenitors throughout life. - cell - tertiary pigment cell @@ -13505,16 +5814,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell at the front of a migrating epithelial sheet. - cell - leading edge cell - - - - A cell at the front of a migrating epithelial sheet. - MA:ma - @@ -13522,21 +5822,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell of a layer of transitional epithelium in the wall of the bladder, ureter, and renal pelvis, external to the lamina propria. - FMA:84127 - bladder transitional cell - transitional epithelial cell of urinary bladder - urinary tract transitional epithelial cell - cell - urothelial cell - - - - A cell of a layer of transitional epithelium in the wall of the bladder, ureter, and renal pelvis, external to the lamina propria. - GOC:tfm - MA:ma - @@ -13544,8 +5830,6 @@ radial glial cells acting as neural progenitors throughout life. - cell - amoeboid cell @@ -13555,8 +5839,6 @@ radial glial cells acting as neural progenitors throughout life. - cell - lymph gland plasmatocyte @@ -13566,8 +5848,6 @@ radial glial cells acting as neural progenitors throughout life. - cell - embryonic gland plasmatocyte @@ -13576,8 +5856,6 @@ radial glial cells acting as neural progenitors throughout life. - cell - lymph gland hemocyte @@ -13586,8 +5864,6 @@ radial glial cells acting as neural progenitors throughout life. - cell - embryonic gland hemocyte @@ -13596,20 +5872,8 @@ radial glial cells acting as neural progenitors throughout life. - Muscle cell which has as its direct parts myofilaments organized into sarcomeres. - BTO:0002916 - CALOHA:TS-2157 - FMA:86936 - cell - striated muscle cell + - - - - Muscle cell which has as its direct parts myofilaments organized into sarcomeres. - GOC:tfm - ISBN:0721662544 - @@ -13618,24 +5882,7 @@ radial glial cells acting as neural progenitors throughout life. - An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue. - BTO:0000751 - CALOHA:TS-0549 - FMA:62852 - immune cell - leucocyte - white blood cell - cell - leukocyte - - - - - An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue. - GOC:add - GOC:tfm - ISBN:978-0-323-05290-0 - + @@ -13644,21 +5891,7 @@ radial glial cells acting as neural progenitors throughout life. - The set of neurons that receives neural inputs via bipolar, horizontal and amacrine cells. The axons of these cells make up the optic nerve. - BTO:0001800 - FMA:67765 - RGC - gangliocyte - ganglion cell of retina - cell - retinal ganglion cell - - - - The set of neurons that receives neural inputs via bipolar, horizontal and amacrine cells. The axons of these cells make up the optic nerve. - GOC:dph - @@ -13666,17 +5899,7 @@ radial glial cells acting as neural progenitors throughout life. - A motor neuron that is located in the cervical region of the spinal cord and selectively innervates the sternocleidmastoid or trapezius muscle. Unlike other motor neurons, they extend axons dorsally along lateral margins of the spinal cord. - SACMN - cell - spinal accessory motor neuron - - - - A motor neuron that is located in the cervical region of the spinal cord and selectively innervates the sternocleidmastoid or trapezius muscle. Unlike other motor neurons, they extend axons dorsally along lateral margins of the spinal cord. - PMID:16267219 - @@ -13684,16 +5907,7 @@ radial glial cells acting as neural progenitors throughout life. - A round chondrocyte that first differentiates in the late embryonic growth plate of bone. - cell - periarticular chondrocyte - - - - A round chondrocyte that first differentiates in the late embryonic growth plate of bone. - PMID:15951842 - @@ -13701,18 +5915,7 @@ radial glial cells acting as neural progenitors throughout life. - Chondrocyte that is terminally differentiated, produces type X collagen, is large in size, and often associated with the replacement of cartilage by bone (endochondral ossification). - cell - is hypertrophic pathological or normal? and can it be described using a pato term? - hypertrophic chondrocyte - - - - Chondrocyte that is terminally differentiated, produces type X collagen, is large in size, and often associated with the replacement of cartilage by bone (endochondral ossification). - GO_REF:0000034 - PMID:15951842 - @@ -13720,16 +5923,7 @@ radial glial cells acting as neural progenitors throughout life. - A columnar chondrocyte that differentiates in the late embryonic growth plate of bone. Columnar chondrocytes vigorously proliferate and form columns in the growth plate. - cell - columnar chondrocyte - - - - A columnar chondrocyte that differentiates in the late embryonic growth plate of bone. Columnar chondrocytes vigorously proliferate and form columns in the growth plate. - PMID:15951842 - @@ -13738,18 +5932,7 @@ radial glial cells acting as neural progenitors throughout life. - A neuron that laterally connects other neurons in the inner nuclear layer of the retina. - BTO:0004120 - horizontal cell - cell - retina horizontal cell - - - - A neuron that laterally connects other neurons in the inner nuclear layer of the retina. - ISBN:0195088433 - @@ -13758,36 +5941,7 @@ radial glial cells acting as neural progenitors throughout life. - Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. In mammals, the contractile fiber resembles those of skeletal muscle but are only one third as large in diameter, are richer in sarcoplasm, and contain centrally located instead of peripheral nuclei. - FMA:83808 - cardiocyte - BTO:0001539 - CALOHA:TS-0115 - FMA:14067 - cardiac muscle fiber - cardiac myocyte - cardiomyocyte - heart muscle cell - cell - This class encompasses the muscle cells responsible for heart* contraction in both vertebrates and arthropods. The ultrastucture of a wide range of arthropod heart cells has been examined including spiders, horseshoe crabs, crustaceans (see Sherman, 1973 and refs therein) and insects (see Lehmacher et al (2012) and refs therein). According to these refs, the cells participating in heart contraction in all cases are transversely striated. Insects hearts additionally contain ostial cells, also transversely striated muscle cells, but which do not participate in heart contraction. - cardiac muscle cell - - - - - Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. In mammals, the contractile fiber resembles those of skeletal muscle but are only one third as large in diameter, are richer in sarcoplasm, and contain centrally located instead of peripheral nuclei. - GOC:mtg_cardiacconduct_nov11 - GOC:tfm - ISBN:0323052908 - PMID:22426062 - PMID:4711263 - - - - - cardiac muscle fiber - GO:0048739 - + @@ -13795,17 +5949,7 @@ radial glial cells acting as neural progenitors throughout life. - A pigment cell derived from the neural crest. Contains blue pigment of unknown chemical composition in fibrous organelles termed cyanosomes. This gives a blue appearance. - cell - blue chromatophore - cyanophore - - - - A pigment cell derived from the neural crest. Contains blue pigment of unknown chemical composition in fibrous organelles termed cyanosomes. This gives a blue appearance. - SANBI:mhl - @@ -13813,17 +5957,11 @@ radial glial cells acting as neural progenitors throughout life. + + + - A bipolar neuron found in the retina and having connections with photoreceptors cells and neurons in the inner plexiform layer. - cell - retinal bipolar neuron - - - - A bipolar neuron found in the retina and having connections with photoreceptors cells and neurons in the inner plexiform layer. - PMID:14689473 - @@ -13831,16 +5969,7 @@ radial glial cells acting as neural progenitors throughout life. - A bipolar neuron found in the retina and having connections with photoreceptors cells and neurons in the inner half of the inner plexiform layer. These cells depolarize in response to light stimulation of their corresponding photoreceptors. - cell - ON-bipolar cell - - - - A bipolar neuron found in the retina and having connections with photoreceptors cells and neurons in the inner half of the inner plexiform layer. These cells depolarize in response to light stimulation of their corresponding photoreceptors. - PMID:14689473 - @@ -13848,35 +5977,15 @@ radial glial cells acting as neural progenitors throughout life. - A bipolar neuron found in the retina and having connections with photoreceptors cells and neurons in the outer half of the inner plexiform layer. These cells hyperpolarize in response to light stimulation of their corresponding photoreceptors. - cell - OFF-bipolar cell - - - - A bipolar neuron found in the retina and having connections with photoreceptors cells and neurons in the outer half of the inner plexiform layer. These cells hyperpolarize in response to light stimulation of their corresponding photoreceptors. - PMID:14689473 - - - A bipolar neuron found in the retina and having connections with rod photoreceptor cells and neurons in the inner plexiform layer. - FMA:67750 - cell - rod bipolar cell + - - - - A bipolar neuron found in the retina and having connections with rod photoreceptor cells and neurons in the inner plexiform layer. - GOC:tfm - PMID:14689473 - @@ -13884,187 +5993,79 @@ radial glial cells acting as neural progenitors throughout life. - A bipolar neuron found in the retina and having connections with cone photoreceptor cells and neurons in the inner plexiform layer. - cell - cone retinal bipolar cell - - - - A bipolar neuron found in the retina and having connections with cone photoreceptor cells and neurons in the inner plexiform layer. - PMID:14689473 - - - An OFF-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the outer half of the inner plexiform layer. The cell body of these cells is in the middle of the inner plexiform layer. The dendritic tree is stout and the axon terminates in sublamina 1. The axonal terminal is wide and has only a few varicosities. - DB1 cone bipolar cell - cell - type 1 cone bipolar cell (sensu Mus) - - - - An OFF-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the outer half of the inner plexiform layer. The cell body of these cells is in the middle of the inner plexiform layer. The dendritic tree is stout and the axon terminates in sublamina 1. The axonal terminal is wide and has only a few varicosities. - PMID:14689473 - - - An OFF-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the outer half of the inner plexiform layer. The dendritic tree is not well filled and the dendrites are more delicate than in type 1 cells. The axon terminal is bushier and exhibits a dense plexus of varicosities in the inner part of sublamina 1. - FMB cone bipolar cell - cell - type 2 cone bipolar cell (sensu Mus) - - - - An OFF-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the outer half of the inner plexiform layer. The dendritic tree is not well filled and the dendrites are more delicate than in type 1 cells. The axon terminal is bushier and exhibits a dense plexus of varicosities in the inner part of sublamina 1. - PMID:14689473 - - - An OFF-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the outer half of the inner plexiform layer. The dendritic tree is delicate and the dendritic tips appear small when compared with type 1 cells. The axon terminal is stratified and restricted to sublamina 2 of the inner plexiform layer. - DB2 cone bipolar cell - cell - type 3 cone bipolar cell (sensu Mus) - - - - An OFF-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the outer half of the inner plexiform layer. The dendritic tree is delicate and the dendritic tips appear small when compared with type 1 cells. The axon terminal is stratified and restricted to sublamina 2 of the inner plexiform layer. - PMID:14689473 - - - An OFF-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the outer half of the inner plexiform layer. The cell has a diffuse axon terminal with varicosities in sublaminae 1 and 2 of the inner plexiform layer. - DB3 cone bipolar cell - cell - type 4 cone bipolar cell (sensu Mus) - - - - An OFF-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the outer half of the inner plexiform layer. The cell has a diffuse axon terminal with varicosities in sublaminae 1 and 2 of the inner plexiform layer. - PMID:14689473 - - - An ON-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the inner half of the inner plexiform layer. The axon terminal is restricted to sublamina 3 of the inner plexiform layer. It is narrowly stratified and branched. The dendritic tree has many delicate branches. - DB4 cone bipolar cell - cell - type 5 cone bipolar cell (sensu Mus) - - - - An ON-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the inner half of the inner plexiform layer. The axon terminal is restricted to sublamina 3 of the inner plexiform layer. It is narrowly stratified and branched. The dendritic tree has many delicate branches. - PMID:14689473 - - - An ON-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the inner half of the inner plexiform layer. The cell has a loose, delicate axon terminal that opens in sublamina 3 of the inner plexiform layer and descends into sublamina 4. - DB5 cone bipolar cell - cell - type 6 cone bipolar cell (sensu Mus) - - - - An ON-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the inner half of the inner plexiform layer. The cell has a loose, delicate axon terminal that opens in sublamina 3 of the inner plexiform layer and descends into sublamina 4. - PMID:14689473 - - - An ON-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the inner half of the inner plexiform layer. The axon terminal is narrowly stratified and are found just below a calretinin-expressing band in sublamina 4 of the inner plexiform layer. - IMB cone bipolar cell - cell - type 7 cone bipolar cell (sensu Mus) - - - - An ON-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the inner half of the inner plexiform layer. The axon terminal is narrowly stratified and are found just below a calretinin-expressing band in sublamina 4 of the inner plexiform layer. - PMID:14689473 - - - An ON-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the inner half of the inner plexiform layer. This cell has the widest dendritic field and the widest axon terminal of all retinal bipolar cells. The axon terminal is delicate and stratified through sublaminae 4 and 5 of the inner plexiform layer. - DB6 cone bipolar cell - cell - type 8 cone bipolar cell (sensu Mus) - - - - An ON-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the inner half of the inner plexiform layer. This cell has the widest dendritic field and the widest axon terminal of all retinal bipolar cells. The axon terminal is delicate and stratified through sublaminae 4 and 5 of the inner plexiform layer. - PMID:14689473 - - - An ON-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the inner half of the inner plexiform layer. The dendritic tree is wide and the dendritic convergence indicates cone selectivity. The axon terminal is sparsely branched and terminates in sublamina 5 of the inner plexiform layer. - BB cone bipolar cell - cell - type 9 cone bipolar cell (sensu Mus) - - - - An ON-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the inner half of the inner plexiform layer. The dendritic tree is wide and the dendritic convergence indicates cone selectivity. The axon terminal is sparsely branched and terminates in sublamina 5 of the inner plexiform layer. - PMID:14689473 - @@ -14073,19 +6074,7 @@ radial glial cells acting as neural progenitors throughout life. - A nucleated blood cell involved in coagulation, typically seen in birds and other non-mammalian vertebrates. - cell - Note that this is a non-mammalian cell type. Use platelet ; CL:0000233 for thrombocytes (platelets) in mammals. - nucleated thrombocyte - - - - A nucleated blood cell involved in coagulation, typically seen in birds and other non-mammalian vertebrates. - GOC:add - GOC:tfm - PMID:16360205 - @@ -14093,18 +6082,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage. - BTO:0001441 - CALOHA:TS-0647 - cell - myeloid cell - - - - A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage. - GOC:add - @@ -14112,23 +6090,7 @@ radial glial cells acting as neural progenitors throughout life. - A immature or mature cell in the lineage leading to and including erythrocytes. - CL:0002156 - CALOHA:TS-0290 - FMA:62845 - FMA:83516 - erythropoietic cell - cell - Note that in FMA erythropoietic cells are types of nucleated erythrocytes and thus don't include erythrocytes. - erythroid lineage cell - - - - - A immature or mature cell in the lineage leading to and including erythrocytes. - GOC:add - GOC:tfm - + @@ -14138,22 +6100,7 @@ radial glial cells acting as neural progenitors throughout life. - A nucleated precursor of an erythrocyte that lacks hematopoietic lineage markers. - BTO:0001571 - CALOHA:TS-0289 - FMA:83504 - normoblast - cell - erythroblast - - - - A nucleated precursor of an erythrocyte that lacks hematopoietic lineage markers. - GOC:add - ISBN:0721601464 - PMID:18174176 - @@ -14162,16 +6109,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell of the monocyte, granulocyte, or mast cell lineage. - cell - myeloid leukocyte - - - - A cell of the monocyte, granulocyte, or mast cell lineage. - GOC:add - @@ -14179,34 +6117,7 @@ radial glial cells acting as neural progenitors throughout life. - Any of the immature or mature forms of a granular leukocyte that in its mature form has an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm that contains coarse, bluish-black granules of variable size. Basophils contain vasoactive amines such as histamine and serotonin, which are released on appropriate stimulation. A basophil is CD123-positive, CD193-positive, CD203c-positive, and FceRIa-positive. - polymorphonuclear leucocyte - polymorphonuclear leukocyte - BTO:0000129 - CALOHA:TS-0073 - FMA:62862 - basophilic leucocyte - basophilic leukocyte - cell - Matures in the bone marrow and account for <1% of leukocytes in the peripheral blood, spleen, and bone marrow. Basophils are described as being CD11a-positive, CD11b-positive, CD13-positive, CD15-positive, CD18-positive, CD21-positive, CD25-positive, CD29-positive, CD35-positive, CD40-positive, CD40L-positive, CD44-positive, CD45R-negative, CD46-positive, CD49a-positive, CD49b-positive, CD49d-positive, CD55-positive, CD59-positive, CD62L-positive, CD63-positive, CD69-positive, CD90-negative, CD116-positive, CD117-negative, CD124-positive, CD125-positive, CD131-positive, CD161-positive, CD184-positive, CD191-positive, CD192-positive, CD197-positive, CD200R3-positive, CD218-positive, CD282-positive, CD284-positive, CD289-positive, CD290-positive, CD294-positive, natural killer cell receptor 2B4-positive, smad1-positive, CD3-negative, CD4-negative, CD7-negative, CD8-negative, CD14-negative, CD15-negative, CD16-negative, CD19-negative, CD20-negative, CD34-negative, CD36-negative, CD45R-negative, CD56-negative, CD57-negative, CD235a-negative, and GR1-negative. Transcription factors- GATA1-positive, PU.1-positive. - basophil - - - - - Any of the immature or mature forms of a granular leukocyte that in its mature form has an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm that contains coarse, bluish-black granules of variable size. Basophils contain vasoactive amines such as histamine and serotonin, which are released on appropriate stimulation. A basophil is CD123-positive, CD193-positive, CD203c-positive, and FceRIa-positive. - GOC:add - GOC:amm - GOC:dsd - GOC:tfm - ISBN:0721601464 - MESH:D001491 - PMCID:PMC2626675 - PMID:11927641 - PMID:19741522 - PMID:21236338 - PMID:9933081 - + @@ -14215,19 +6126,7 @@ radial glial cells acting as neural progenitors throughout life. - Any of the immature forms of a basophil, in which basophilic specific granules are present but other phenotypic features of the mature form may be lacking. - immature basophilic leucocyte - immature basophilic leukocyte - cell - immature basophil - - - - Any of the immature forms of a basophil, in which basophilic specific granules are present but other phenotypic features of the mature form may be lacking. - GOC:add - ISBN:0721601464 - @@ -14236,19 +6135,7 @@ radial glial cells acting as neural progenitors throughout life. - A basophil precursor in the granulocytic series, being a cell intermediate in development between a basophilic myelocyte and a band form basophil. The nucleus becomes indented where the indentation is smaller than half the distance to the farthest nuclear margin; chromatin becomes coarse and clumped; specific granules predominate while primary granules are rare. Markers are CD11b-positive, CD15-positive, CD16-positive, CD24-positive, CD33-positive, and CD13-positive. - FMA:84198 - cell - basophilic metamyelocyte - - - - A basophil precursor in the granulocytic series, being a cell intermediate in development between a basophilic myelocyte and a band form basophil. The nucleus becomes indented where the indentation is smaller than half the distance to the farthest nuclear margin; chromatin becomes coarse and clumped; specific granules predominate while primary granules are rare. Markers are CD11b-positive, CD15-positive, CD16-positive, CD24-positive, CD33-positive, and CD13-positive. - GOC:tfm - ISBN:0721601464 - PMID:18466030 - @@ -14256,19 +6143,7 @@ radial glial cells acting as neural progenitors throughout life. - A late basophilic metamyelocyte in which the nucleus is in the form of a curved or coiled band, not having acquired the typical multilobar shape of the mature basophil. - cell - band form basophil - - - - A late basophilic metamyelocyte in which the nucleus is in the form of a curved or coiled band, not having acquired the typical multilobar shape of the mature basophil. - GOC:add - ISBN:0721601464 - PMID:18466030 - http://www.cap.org - @@ -14276,33 +6151,7 @@ radial glial cells acting as neural progenitors throughout life. - Any of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin. Eosinophils are CD9-positive, CD191-positive, and CD193-positive. - polymorphonuclear leucocyte - polymorphonuclear leukocyte - BTO:0000399 - CALOHA:TS-0279 - FMA:62861 - eosinocyte - eosinophilic granulocyte - eosinophilic leucocyte - eosinophilic leukocyte - cell - Eosinophils are also CD14-negative, CD32-positive, CD44-positive, CD48-positive, CD69-positive, CD192-negative, MBP1-positive, MBP2-positive, TLR2-negative, TLR4-negative, and lineage-negative (B220, CD2, CD14, CD19, CD56, CD71, CD117, CD123, CD235a (glycophorin A), and TER119). The cytokines IL-3, IL-5, and GM-CSF are involved in their development and differentiation. Usually considered CD16-negative, CD16 is observed on eosinophilic metamyelocyte. - eosinophil - - - - - Any of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin. Eosinophils are CD9-positive, CD191-positive, and CD193-positive. - GOC:add - GOC:amm - GOC:dsd - GOC:tfm - ISBN:0721601464 - PMCID:PMC2626675 - PMID:10914487 - PMID:1662676 - + @@ -14311,20 +6160,7 @@ radial glial cells acting as neural progenitors throughout life. - Any of the immature forms of an eosinophil, in which eosinophilic specific granules are present but other phenotypic features of the mature form may be lacking. - immature eosinocyte - immature eosinophilic leucocyte - immature eosinophilic leukocyte - cell - immature eosinophil - - - - Any of the immature forms of an eosinophil, in which eosinophilic specific granules are present but other phenotypic features of the mature form may be lacking. - GOC:add - ISBN:0721601464 - @@ -14333,19 +6169,7 @@ radial glial cells acting as neural progenitors throughout life. - A eosinophil precursor in the granulocytic series, being a cell intermediate in development between a eosinophilic myelocyte and a band form eosinophil. The nucleus becomes indented where the indentation is smaller than half the distance to the farthest nuclear margin; chromatin becomes coarse and clumped; specific granules predominate while primary granules are rare. Markers are integrin alpha-M-positive, fucosyltransferase FUT4-positive, low affinity immunoglobulin gamma Fc region receptor III-positive, CD33-positive, CD24-positive and aminopeptidase N-negative. - cell - eosinophilic metamyelocyte - - - - A eosinophil precursor in the granulocytic series, being a cell intermediate in development between a eosinophilic myelocyte and a band form eosinophil. The nucleus becomes indented where the indentation is smaller than half the distance to the farthest nuclear margin; chromatin becomes coarse and clumped; specific granules predominate while primary granules are rare. Markers are integrin alpha-M-positive, fucosyltransferase FUT4-positive, low affinity immunoglobulin gamma Fc region receptor III-positive, CD33-positive, CD24-positive and aminopeptidase N-negative. - GOC:add - GOC:tfm - ISBN:0721601464 - PMID:19622087 - @@ -14353,20 +6177,7 @@ radial glial cells acting as neural progenitors throughout life. - A late eosinophilic metamyelocyte in which the nucleus is in the form of a curved or coiled band, not having acquired the typical multilobar shape of the mature basophil. - cell - band form eosinophil - - - - A late eosinophilic metamyelocyte in which the nucleus is in the form of a curved or coiled band, not having acquired the typical multilobar shape of the mature basophil. - GOC:add - GOC:tfm - ISBN:0721601464 - PMID:19622087 - http://www.cap.org - @@ -14374,34 +6185,7 @@ radial glial cells acting as neural progenitors throughout life. - Any of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes. - PMN - poly - polymorphonuclear leucocyte - polymorphonuclear leukocyte - polymorphonuclear neutrophil - polynuclear neutrophilic leucocyte - polynuclear neutrophilic leukocyte - BTO:0000130 - CALOHA:TS-0688 - FMA:62860 - neutrocyte - neutrophil leucocyte - neutrophil leukocyte - neutrophilic leucocyte - neutrophilic leukocyte - cell - neutrophil - - - - - Any of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes. - GOC:add - GOC:amm - GOC:tfm - ISBN:0721601464 - + @@ -14410,22 +6194,7 @@ radial glial cells acting as neural progenitors throughout life. - Any of the immature forms of a neutrophil in which neutrophilic specific granules are present but other phenotypic features of the mature form may be lacking. - immatuer neutrophilic leukocyte - immature neutrocyte - immature neutrophil leucocyte - immature neutrophil leukocyte - immature neutrophilic leucocyte - cell - immature neutrophil - - - - Any of the immature forms of a neutrophil in which neutrophilic specific granules are present but other phenotypic features of the mature form may be lacking. - GOC:add - ISBN:0721601464 - @@ -14433,22 +6202,7 @@ radial glial cells acting as neural progenitors throughout life. - A tissue-resident macrophage of the renal glomerular mesangium involved in the disposal and degradation of filtration residues, presentation of antigen to T cells and in tissue remodeling. - mesangial cell - cell - mesangial phagocyte - - - - A tissue-resident macrophage of the renal glomerular mesangium involved in the disposal and degradation of filtration residues, presentation of antigen to T cells and in tissue remodeling. - GOC:add - GOC:tfm - ISBN:0702022918 - ISBN:3540536663 - PMID:1600140 - PMID:16146841 - @@ -14457,22 +6211,7 @@ radial glial cells acting as neural progenitors throughout life. - A specialized mononuclear osteoclast associated with the absorption and removal of bone, precursor of multinuclear osteoclasts. - cell - Morphology: mononuclear, highly vesicular. - mononuclear osteoclast - - - - A specialized mononuclear osteoclast associated with the absorption and removal of bone, precursor of multinuclear osteoclasts. - GOC:add - GOC:tfm - PMID:12713016 - PMID:15055519 - PMID:17380158 - PMID:9415452 - @@ -14481,20 +6220,7 @@ radial glial cells acting as neural progenitors throughout life. - A specialized multinuclear osteoclast associated with the absorption and removal of bone. - multinucleated osteoclast - cell - Morphology: multinucleated, highly vesicular. - multinuclear osteoclast - - - - A specialized multinuclear osteoclast associated with the absorption and removal of bone. - GOC:add - PMID:12713016 - PMID:9415452 - @@ -14503,19 +6229,7 @@ radial glial cells acting as neural progenitors throughout life. - A specialized multinuclear osteoclast associated with the absorption and removal of cementum. - multinucleated odontoclast - cell - Morphology: multinucleated, highly vesicular; location: roots of deciduous (milk) teeth. - multinuclear odontoclast - - - - A specialized multinuclear osteoclast associated with the absorption and removal of cementum. - GOC:add - PMID:9415452 - @@ -14524,18 +6238,7 @@ radial glial cells acting as neural progenitors throughout life. - A specialized mononuclear osteoclast associated with the absorption and removal of cementum. - cell - Morphology: Mononuclear, highly vesicular; location: roots of deciduous (milk) teeth. - mononuclear odontoclast - - - - A specialized mononuclear osteoclast associated with the absorption and removal of cementum. - GOC:add - PMID:9415452 - @@ -14544,25 +6247,7 @@ radial glial cells acting as neural progenitors throughout life. - A dendritic cell of the myeloid lineage. - interdigitating cell - veiled cell - BTO:0004721 - CD11c+CD123- DC - mDC - cell - These cells are CD1a-negative, CD1b-positive, CD11a-positive, CD11c-positive, CD13-positive, CD14-negative, CD20-negative, CD21-negative, CD33-positive, CD40-negative, CD50-positive, CD54-positive, CD58-positive, CD68-negative, CD80-negative, CD83-negative, CD85j-positive, CD86-positive, CD89-negative, CD95-positive, CD120a-negative, CD120b-positive, CD123-negative, CD178-negative, CD206-negative, CD207-negative, CD209-negative, and TNF-alpha-negative. Upon TLR stimulation, they are capable of producing high levels of TNF-alpha, IL-6, CXCL8 (IL-8). - myeloid dendritic cell - - - - - A dendritic cell of the myeloid lineage. - GOC:add - PMID:10449155 - PMID:17332250 - PMID:9521319 - + @@ -14571,17 +6256,7 @@ radial glial cells acting as neural progenitors throughout life. - A phagocyte formed by the fusion of mononuclear phagocytes. - cell - multinucleated phagocyte - - - - A phagocyte formed by the fusion of mononuclear phagocytes. - GOC:add - GOC:tfm - @@ -14589,33 +6264,7 @@ radial glial cells acting as neural progenitors throughout life. - A dendritic cell type of distinct morphology, localization, and surface marker expression (CD123-positive) from other dendritic cell types and associated with early stage immune responses, particularly the release of physiologically abundant amounts of type I interferons in response to infection. - BTO:0004625 - DC2 - IPC - T-associated plasma cell - interferon-producing cell - lymphoid dendritic cell - pDC - plasmacytoid T cell - plasmacytoid monocyte - type 2 DC - cell - plasmacytoid dendritic cell - - - - - A dendritic cell type of distinct morphology, localization, and surface marker expression (CD123-positive) from other dendritic cell types and associated with early stage immune responses, particularly the release of physiologically abundant amounts of type I interferons in response to infection. - GOC:add - GOC:dsd - PMCID:PMC2118448 - PMCID:PMC538703 - PMID:15549123 - PMID:17332250 - PMID:17850486 - PMID:20304825 - + @@ -14623,22 +6272,10 @@ radial glial cells acting as neural progenitors throughout life. - A B cell that is mature, having left the bone marrow. Initially, these cells are IgM-positive and IgD-positive, and they can be activated by antigen. - mature B lymphocyte - mature B-cell - mature B-lymphocyte - cell - Mature B cells are also reportedly CD10-negative, CD19-positive, CD22-positive, CD34-negative, CD48-positive, CD79a-positive, CD84-positive, CD127-negative, CD352-positive, RAG-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Transcription factors expressed: Pax5-positive. - mature B cell + + + - - - - A B cell that is mature, having left the bone marrow. Initially, these cells are IgM-positive and IgD-positive, and they can be activated by antigen. - GOC:add - GOC:dsd - ISBN:0781735149 - @@ -14646,34 +6283,7 @@ radial glial cells acting as neural progenitors throughout life. - A terminally differentiated, post-mitotic, antibody secreting cell of the B cell lineage with the phenotype CD138-positive, surface immunonoglobulin-negative, and MHC Class II-negative. Plasma cells are oval or round with extensive rough endoplasmic reticulum, a well-developed Golgi apparatus, and a round nucleus having a characteristic cartwheel heterochromatin pattern and are devoted to producing large amounts of immunoglobulin. - BTO:0000392 - FMA:70574 - plasma B cell - plasma B-cell - plasmacyte - plasmocyte - cell - effector B cell - effector B-cell - Plasma cells develop in the spleen and migrate to the bone marrow. Plasma cells are also reportedly CD5-negative, CD10-negative, CD19-positive, CD20-negative, CD21-negative, CD22-negative, CD23-negative, CD24-negative, CD25-negative, CD27-positive, CD34-negative, CD38-positive, CD40-positive, CD43-positive, CD45-positive, CD48-positive, CD53-low, CD80-negative, CD81-positive, CD86-positive, CD95-positive, CD196-negative, CD229-positive, CD270-positive, CD352-positive, CD361-positive, and IgD-negative. Transcription factors: BLIMP1-positive, IRF4-positive, PAX5-negative, SpiB-negative, Ets1-negative, and XBP1-positive. - plasma cell - - - - - A terminally differentiated, post-mitotic, antibody secreting cell of the B cell lineage with the phenotype CD138-positive, surface immunonoglobulin-negative, and MHC Class II-negative. Plasma cells are oval or round with extensive rough endoplasmic reticulum, a well-developed Golgi apparatus, and a round nucleus having a characteristic cartwheel heterochromatin pattern and are devoted to producing large amounts of immunoglobulin. - GOC:add - GOC:dsd - GO_REF:0000031 - ISBN:0721601464 - ISBN:0781735149 - PMID:19447676 - PMID:20081059 - PMID:20839338 - PMID:20951740 - http://en.wikipedia.org/wiki/Plasma_cell - + @@ -14681,27 +6291,7 @@ radial glial cells acting as neural progenitors throughout life. - A memory B cell is a mature B cell that is long-lived, readily activated upon re-encounter of its antigenic determinant, and has been selected for expression of higher affinity immunoglobulin. This cell type has the phenotype CD19-positive, CD20-positive, MHC Class II-positive, and CD138-negative. - memory B lymphocyte - memory B-cell - memory B-lymphocyte - cell - Memory B-cells are also reportedly CD5-negative, CD10-negative, CD21-positive, CD22-positive, CD23-negative, CD24-positive, CD25-positive, CD27-positive, CD34-negative, CD38-negative, CD40-positive, CD43-negative, CD44-positive, CD45-positive, CD53-positive, CD80-negative, CD81-negative, CD86-positive, and CD196/CCR6-positive. - memory B cell - - - - - A memory B cell is a mature B cell that is long-lived, readily activated upon re-encounter of its antigenic determinant, and has been selected for expression of higher affinity immunoglobulin. This cell type has the phenotype CD19-positive, CD20-positive, MHC Class II-positive, and CD138-negative. - GOC:add - GOC:dsd - GOC:rhs - GO_REF:0000031 - ISBN:0781735149 - PMID:20081059 - PMID:20839338 - http://en.wikipedia.org/wiki/Memory_B_cell - + @@ -14709,29 +6299,7 @@ radial glial cells acting as neural progenitors throughout life. - A naive B cell is a mature B cell that has the phenotype surface IgD-positive, surface IgM-positive, CD20-positive, CD27-negative and that has not yet been activated by antigen in the periphery. - naive B lymphocyte - naive B-cell - naive B-lymphocyte - cell - This cell type is compatible with the HIPC Lyoplate markers for 'naive B cell'. Per DSD: Naive B cells are also reportedly CD10-negative, CD19-positive, CD20-positive, CD21-positive, CD22-positive, CD25-negative, CD27-negative, CD34-negative, CD40-positive, CD43-negative, CD45-positive, CD48-positive, CD53-positive, CD80-negative, CD81-positive, CD84-positive, CD86-negative, CD95-negative, CD138-negative, CD150-positive, CD184/CXCR4-positive, CD185/CXCR5-positive, CD196/CCR6-positive, CD200-positive, CD229-positive, CD243-positive, CD289-positive, CD290-positive, CD352-positive, MHCII/HLA-DR-positive, cadherin 9-positive, and sIgH-positive, Transcription factors: Pax5-positive, ETS1-positive, FOXO1A-positive, KLF4-positive, KLF9-positive, MiTF-positive, OBF1-positive, PLZF-positive, and SpiB-positive. - naive B cell - - - - - A naive B cell is a mature B cell that has the phenotype surface IgD-positive, surface IgM-positive, CD20-positive, CD27-negative and that has not yet been activated by antigen in the periphery. - GOC:add - GOC:dsd - GOC:rhs - GO_REF:0000031 - ISBN:0781765196 - PMID:19447676 - PMID:20081059 - PMID:20839338 - PMID:20933013 - PMID:22343568 - + @@ -14739,21 +6307,8 @@ radial glial cells acting as neural progenitors throughout life. - A T cell that expresses an alpha-beta T cell receptor complex. - alpha-beta T lymphocyte - alpha-beta T-cell - alpha-beta T-lymphocyte - cell - alpha-beta T cell + - - - - A T cell that expresses an alpha-beta T cell receptor complex. - GOC:add - GOC:tfm - ISBN:0781735149 - @@ -14762,21 +6317,7 @@ radial glial cells acting as neural progenitors throughout life. - An alpha-beta T cell that has an immature phenotype and has not completed T cell selection. - immature alpha-beta T lymphocyte - immature alpha-beta T-cell - immature alpha-beta T-lymphocyte - cell - immature alpha-beta T cell - - - - An alpha-beta T cell that has an immature phenotype and has not completed T cell selection. - GOC:add - GOC:tfm - ISBN:0781735149 - @@ -14785,21 +6326,7 @@ radial glial cells acting as neural progenitors throughout life. - A alpha-beta T cell that has a mature phenotype. - mature alpha-beta T lymphocyte - mature alpha-beta T-cell - mature alpha-beta T-lymphocyte - cell - mature alpha-beta T cell - - - - A alpha-beta T cell that has a mature phenotype. - GOC:add - GOC:tfm - ISBN:0781735149 - @@ -14808,35 +6335,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD4-positive, CD25-positive, alpha-beta T cell that regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release. - Treg - suppressor T cell - suppressor T lymphocyte - suppressor T-cell - suppressor T-lymphocyte - CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte - CD4-positive, CD25-positive, alpha-beta regulatory T-cell - CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte - cell - This cell type is compatible with the HIPC Lyoplate markers for 'Treg'. The inclusion of CD127lo in the logical definition is compatible with both human and mouse T cells of this subtype. - CD4-positive, CD25-positive, alpha-beta regulatory T cell - - - - - A CD4-positive, CD25-positive, alpha-beta T cell that regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release. - GOC:add - GOC:tfm - ISBN:0781735149 - PMID:19464985 - PMID:22343568 - - - - - Treg - PMID:22343568 - + @@ -14845,23 +6344,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD4-positive, alpha-beta T cell that is found in the columnar epithelium of the gastrointestinal tract. - IEL - intraepithelial lymphocyte - CD4-positive, alpha-beta intraepithelial T lymphocyte - CD4-positive, alpha-beta intraepithelial T-cell - CD4-positive, alpha-beta intraepithelial T-lymphocyte - cell - CD4-positive, alpha-beta intraepithelial T cell - - - - - A CD4-positive, alpha-beta T cell that is found in the columnar epithelium of the gastrointestinal tract. - GOC:add - GOC:tfm - ISBN:0781735149 - + @@ -14870,34 +6353,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD8-positive, alpha-beta T cell that is capable of killing target cells in an antigen specific manner with the phenotype perforin-positive and granzyme B-positive. - cytotoxic T cell - cytotoxic T lymphocyte - cytotoxic T-cell - cytotoxic T-lymphocyte - killer T cell - killer T lymphocyte - killer T-cell - killer T-lymphocyte - CALOHA:TS-0190 - FMA:70573 - CD8-positive, alpha-beta cytotoxic T lymphocyte - CD8-positive, alpha-beta cytotoxic T-cell - CD8-positive, alpha-beta cytotoxic T-lymphocyte - cell - Note that while T cells of this subset are loosely referred to 'cytotoxic T cells,' as many other T cell types, including CD4-positive, alpha-beta T cells and gamma-delta T cells exhibit cytotoxicity in vitro and in vivo. - CD8-positive, alpha-beta cytotoxic T cell - - - - - A CD8-positive, alpha-beta T cell that is capable of killing target cells in an antigen specific manner with the phenotype perforin-positive and granzyme B-positive. - GOC:add - GOC:pam - GOC:tfm - GO_REF:0000031 - ISBN:0781735149 - + @@ -14906,31 +6362,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD8-positive, alpha-beta T cell that regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release. - suppressor T cell - suppressor T lymphocyte - suppressor T-cell - suppressor T-lymphocyte - CD8+ T(reg) - CD8+ Treg - CD8+ regulatory T cell - CD8-positive T(reg) - CD8-positive Treg - CD8-positive, alpha-beta Treg - CD8-positive, alpha-beta regulatory T lymphocyte - CD8-positive, alpha-beta regulatory T-cell - CD8-positive, alpha-beta regulatory T-lymphocyte - cell - CD8-positive, alpha-beta regulatory T cell - - - - - A CD8-positive, alpha-beta T cell that regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release. - GOC:add - GOC:tfm - ISBN:0781735149 - + @@ -14938,22 +6370,7 @@ radial glial cells acting as neural progenitors throughout life. - A alpha-beta intraepithelial T cell found in the columnar epithelium of the gastrointestinal tract. Intraepithelial T cells often have distinct developmental pathways and activation requirements. - IEL - intraepithelial lymphocyte - CD8-positive, alpha-beta intraepithelial T lymphocyte - CD8-positive, alpha-beta intraepithelial T-cell - CD8-positive, alpha-beta intraepithelial T-lymphocyte - cell - CD8-alpha-beta-positive, alpha-beta intraepithelial T cell - - - - A alpha-beta intraepithelial T cell found in the columnar epithelium of the gastrointestinal tract. Intraepithelial T cells often have distinct developmental pathways and activation requirements. - GOC:add - ISBN:0781735149 - @@ -14962,23 +6379,7 @@ radial glial cells acting as neural progenitors throughout life. - A mature alpha-beta T cell of the columnar epithelium of the gastrointestinal tract. Intraepithelial T cells often have distinct developmental pathways and activation requirements. - IEL - intraepithelial lymphocyte - alpha-beta intraepithelial T lymphocyte - alpha-beta intraepithelial T-cell - alpha-beta intraepithelial T-lymphocyte - cell - alpha-beta intraepithelial T cell - - - - - A mature alpha-beta T cell of the columnar epithelium of the gastrointestinal tract. Intraepithelial T cells often have distinct developmental pathways and activation requirements. - GOC:add - GOC:tfm - ISBN:0781735149 - + @@ -14986,24 +6387,7 @@ radial glial cells acting as neural progenitors throughout life. - A T cell that expresses a gamma-delta T cell receptor complex. - gamma-delta T lymphocyte - gamma-delta T-cell - gamma-delta T-lymphocyte - gammadelta T cell - cell - gd T cell - Note that gamma-delta T cells have both thymic and extrathymic differentiation pathways. - gamma-delta T cell - - - - - A T cell that expresses a gamma-delta T cell receptor complex. - GOC:add - GOC:tfm - ISBN:0781735149 - + @@ -15012,21 +6396,7 @@ radial glial cells acting as neural progenitors throughout life. - A gamma-delta T cell that has an immature phenotype. - immature gamma-delta T lymphocyte - immature gamma-delta T-cell - immature gamma-delta T-lymphocyte - cell - Note that gamma-delta T cells have both thymic and extrathymic differentiation pathways. - immature gamma-delta T cell - - - - A gamma-delta T cell that has an immature phenotype. - GOC:add - ISBN:0781735149 - @@ -15035,21 +6405,7 @@ radial glial cells acting as neural progenitors throughout life. - A gamma-delta T cell that has a mature phenotype. These cells can be found in tissues and circulation where they express unique TCR repertoire depending on their location. - mature gamma-delta T lymphocyte - mature gamma-delta T-cell - mature gamma-delta T-lymphocyte - cell - mature gamma-delta T cell - - - - A gamma-delta T cell that has a mature phenotype. These cells can be found in tissues and circulation where they express unique TCR repertoire depending on their location. - GOC:add - GOC:tfm - ISBN:0781735149 - @@ -15058,23 +6414,7 @@ radial glial cells acting as neural progenitors throughout life. - A mature gamma-delta T cell that is found in the columnar epithelium of the gastrointestinal tract. These cells participate in mucosal immune responses. - IEL - intraepithelial lymphocyte - gamma-delta intraepithelial T lymphocyte - gamma-delta intraepithelial T-cell - gamma-delta intraepithelial T-lymphocyte - cell - gamma-delta intraepithelial T cell - - - - - A mature gamma-delta T cell that is found in the columnar epithelium of the gastrointestinal tract. These cells participate in mucosal immune responses. - GOC:add - GOC:tfm - ISBN:0781735149 - + @@ -15082,23 +6422,7 @@ radial glial cells acting as neural progenitors throughout life. - A gamma-delta intraepithelial T cell that has the phenotype CD8-alpha alpha-positive. - IEL - intraepithelial lymphocyte - CD8-positive, gamma-delta intraepithelial T lymphocyte - CD8-positive, gamma-delta intraepithelial T-cell - CD8-positive, gamma-delta intraepithelial T-lymphocyte - cell - CD8-alpha alpha positive, gamma-delta intraepithelial T cell - - - - - A gamma-delta intraepithelial T cell that has the phenotype CD8-alpha alpha-positive. - GOC:add - GOC:tfm - ISBN:0781735149 - + @@ -15106,23 +6430,7 @@ radial glial cells acting as neural progenitors throughout life. - A gamma-delta intraepithelial T cell that has the phenotype CD4-negative and CD8-negative. - IEL - intraepithelial lymphocyte - CD4-positive, gamma-delta intraepithelial T lymphocyte - CD4-positive, gamma-delta intraepithelial T-cell - CD4-positive, gamma-delta intraepithelial T-lymphocyte - cell - CD4-negative CD8-negative gamma-delta intraepithelial T cell - - - - - A gamma-delta intraepithelial T cell that has the phenotype CD4-negative and CD8-negative. - GOC:add - GOC:tfm - ISBN:0781735149 - + @@ -15130,26 +6438,7 @@ radial glial cells acting as neural progenitors throughout life. - A thymocyte that has the phenotype CD4-negative, CD8-positive, CD44-negative, CD25-negative, and pre-TCR-positive. - ISP - T.ISP.th - immature single positive T cell - immature single positive T lymphocyte - immature single positive T-lymphocyte - cell - Note that this type of thymocyte has passed the beta-selection checkpoint and is rapidly proliferating and rearranging the T cell receptor alpha chain and expressing the CD8 coreceptor. This stage comes between the DN4 and DP stages. - immature single positive thymocyte - - - - - A thymocyte that has the phenotype CD4-negative, CD8-positive, CD44-negative, CD25-negative, and pre-TCR-positive. - GOC:add - GOC:tfm - GO_REF:0000031 - ISBN:0781735149 - http://www.immgen.org/index_content.html - + @@ -15157,29 +6446,7 @@ radial glial cells acting as neural progenitors throughout life. - A thymocyte that has the phenotype CD4-negative, CD8-negative, CD44-positive, and CD25-positive. - DN2 alpha-beta immature T lymphocyte - DN2 alpha-beta immature T-cell - DN2 alpha-beta immature T-lymphocyte - DN2 cell - DN2 immature T cell - TN2 cell - TN2 thymocyte - double negative 2 - preT.DN2.Th - cell - Note that this type of thymocyte is at the earliest stage of T cell receptor rearrangement of the beta, gamma, and delta T cell receptor chains. - DN2 thymocyte - - - - - A thymocyte that has the phenotype CD4-negative, CD8-negative, CD44-positive, and CD25-positive. - GOC:add - GOC:tfm - GO_REF:0000031 - ISBN:0781735149 - + @@ -15187,29 +6454,7 @@ radial glial cells acting as neural progenitors throughout life. - A thymocyte that has the phenotype CD4-negative, CD8-negative, CD44-negative, and CD25-positive and expressing the T cell receptor beta-chain in complex with the pre-T cell receptor alpha chain. - early cortical thymocyte - DN3 alpha-beta immature T lymphocyte - DN3 alpha-beta immature T-cell - DN3 alpha-beta immature T-lymphocyte - DN3 cell - DN3 immature T cell - TN3 cell - TN3 thymocyte - double negative 3 - preT.DN3.Th - cell - DN3 thymocyte - - - - - A thymocyte that has the phenotype CD4-negative, CD8-negative, CD44-negative, and CD25-positive and expressing the T cell receptor beta-chain in complex with the pre-T cell receptor alpha chain. - GOC:add - GOC:tfm - GO_REF:0000031 - ISBN:0781735149 - + @@ -15217,28 +6462,7 @@ radial glial cells acting as neural progenitors throughout life. - A thymocyte that has the phenotype CD4-negative, CD8-negative, CD44-negative, CD25-negative, and pre-TCR-positive. - early cortical thymocyte - DN4 alpha-beta immature T lymphocyte - DN4 alpha-beta immature T-lymphocyte - DN4 cell - DN4 immature T cell - DN4 immature T-cell - T.DN4.th - double negative 4 - cell - Note that this type of thymocyte has passed the beta-selection checkpoint and is rapidly proliferating and beginning to rearrange the T cell receptor alpha chain. - DN4 thymocyte - - - - - A thymocyte that has the phenotype CD4-negative, CD8-negative, CD44-negative, CD25-negative, and pre-TCR-positive. - GOC:add - GOC:tfm - GO_REF:0000031 - ISBN:0781735149 - + @@ -15247,24 +6471,7 @@ radial glial cells acting as neural progenitors throughout life. - A thymocyte expressing the alpha-beta T cell receptor complex as well as both the CD4 and CD8 coreceptors. - late cortical thymocyte - DP cell - DP thymocyte - double-positive, alpha-beta immature T lymphocyte - cell - Thymocytes of this stage are undergoing positive and negative selection. - double-positive, alpha-beta thymocyte - - - - - A thymocyte expressing the alpha-beta T cell receptor complex as well as both the CD4 and CD8 coreceptors. - GOC:add - GOC:tfm - GO_REF:0000031 - ISBN:0781735149 - + @@ -15273,23 +6480,7 @@ radial glial cells acting as neural progenitors throughout life. - An immature alpha-beta T cell that is located in the thymus and is CD4-positive and CD8-negative. - CD4-positive, alpha-beta immature T lymphocyte - CD4-positive, alpha-beta immature T-cell - CD4-positive, alpha-beta immature T-lymphocyte - SP CD4 cell - cell - CD4-positive, alpha-beta thymocyte - - - - - An immature alpha-beta T cell that is located in the thymus and is CD4-positive and CD8-negative. - GOC:add - GOC:tfm - GO_REF:0000031 - ISBN:0781735149 - + @@ -15298,24 +6489,7 @@ radial glial cells acting as neural progenitors throughout life. - An immature alpha-beta T cell that is located in the thymus and is CD8-positive and CD4-negative. - CD8-positive, alpha-beta immature T lymphocyte - CD8-positive, alpha-beta immature T-cell - CD8-positive, alpha-beta immature T-lymphocyte - SP CD8 cell - cell - CD8-positive, alpha-beta immature T cell - CD8-positive, alpha-beta thymocyte - - - - - An immature alpha-beta T cell that is located in the thymus and is CD8-positive and CD4-negative. - GOC:add - GOC:tfm - GO_REF:0000031 - ISBN:0781735149 - + @@ -15323,24 +6497,8 @@ radial glial cells acting as neural progenitors throughout life. - A distinctly differentiated long-lived T cell that has the phenotype CD45RO-positive and CD127-positive. - BTO:0003435 - memory T lymphocyte - memory T-cell - memory T-lymphocyte - cell - memory T cell - - - - - A distinctly differentiated long-lived T cell that has the phenotype CD45RO-positive and CD127-positive. - GOC:add - GOC:pam - GOC:tfm - GO_REF:0000031 - ISBN:0781735149 - + + @@ -15349,25 +6507,7 @@ radial glial cells acting as neural progenitors throughout life. - A mature alpha-beta T cell of a distinct lineage that bears natural killer markers and a T cell receptor specific for a limited set of ligands. NK T cells have activation and regulatory roles particularly early in an immune response. - mature NK T lymphocyte - mature NK T-cell - mature NK T-lymphocyte - mature NKT cell - mature natural killer T cell - mature natural killer T lymphocyte - mature natural killer T-cell - mature natural killer T-lymphocyte - cell - mature NK T cell - - - - - A mature alpha-beta T cell of a distinct lineage that bears natural killer markers and a T cell receptor specific for a limited set of ligands. NK T cells have activation and regulatory roles particularly early in an immune response. - GOC:add - ISBN:0781735149 - + @@ -15375,27 +6515,7 @@ radial glial cells acting as neural progenitors throughout life. - A T cell which regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release. - suppressor T cell - suppressor T lymphocyte - suppressor T-cell - suppressor T-lymphocyte - BTO:0004520 - FMA:84070 - regulatory T lymphocyte - regulatory T-cell - regulatory T-lymphocyte - cell - This cell type may express FoxP3 and CD25 and secretes IL-10 and TGF-beta. - regulatory T cell - - - - - A T cell which regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release. - GOC:add - GO_REF:0000031 - + @@ -15403,34 +6523,7 @@ radial glial cells acting as neural progenitors throughout life. - An immature B cell is a B cell that has the phenotype surface IgM-positive and surface IgD-negative, and have not undergone class immunoglobulin class switching or peripheral encounter with antigen and activation. - immature B lymphocyte - immature B-cell - immature B-lymphocyte - newly formed B cell - cell - Immature B cells are also reportedly CD5-positive, CD10-positive, CD19-positive, CD20-positive, CD21-positive, CD22-positive, CD24-positive, CD25-negative, CD27-negative, CD34-negative, CD38-positive, CD40-positive, CD43-negative, CD45-positive, CD48-positive, CD53-positive, CD79a-positive, CD80-negative, CD81-positive, CD86-negative, CD95-negative, CD127-negative, CD138-negative, CD185-positive, CD196-positive, MHCII/HLA-DR-positive, RAG-positive, TdT-negative, Vpre-B-negative, and preBCR-negative. Transcription factors expressed: Pax5-positive. - immature B cell - - - - - An immature B cell is a B cell that has the phenotype surface IgM-positive and surface IgD-negative, and have not undergone class immunoglobulin class switching or peripheral encounter with antigen and activation. - GOC:add - GOC:dsd - GOC:rhs - GOC:tfm - GO_REF:0000031 - ISBN:0781735149 - PMID:20081059 - PMID:20839338 - - - - - newly formed B cell - ISBN:781735149 - + @@ -15438,21 +6531,8 @@ radial glial cells acting as neural progenitors throughout life. - A precursor B cell is a B cell with the phenotype CD10-positive. - BTO:0001133 - CALOHA:TS-0819 - cell - pre-B cell - precursor B cell + - - - - A precursor B cell is a B cell with the phenotype CD10-positive. - GOC:rhs - GOC:tfm - GO_REF:0000031 - @@ -15460,34 +6540,7 @@ radial glial cells acting as neural progenitors throughout life. - An immature B cell of an intermediate stage between the pre-B cell stage and the mature naive stage with the phenotype surface IgM-positive and CD19-positive, and are subject to the process of B cell selection. A transitional B cell migrates from the bone marrow into the peripheral circulation, and then to the spleen. - transitional B cell - transitional stage B lymphocyte - transitional stage B-cell - transitional stage B-lymphocyte - T1 B cell - T2 B cell - T3 B cell - cell - This cell type is compatible with the HIPC Lyoplate markers for 'transitional B cell'. - transitional stage B cell - - - - - An immature B cell of an intermediate stage between the pre-B cell stage and the mature naive stage with the phenotype surface IgM-positive and CD19-positive, and are subject to the process of B cell selection. A transitional B cell migrates from the bone marrow into the peripheral circulation, and then to the spleen. - GOC:add - GO_REF:0000031 - ISBN:0781735149 - PMID:12810111 - PMID:22343568 - - - - - transitional B cell - PMID:22343568 - + @@ -15495,32 +6548,7 @@ radial glial cells acting as neural progenitors throughout life. - A B cell of distinct lineage and surface marker expression. B-1 B cells are thought to be the primary source of natural IgM immunoglobulin, that is, IgM produced in large quantities without prior antigenic stimulation and generally reactive against various microorganisms, as well as the source of T-independent IgA immunoglobulin in the mucosal areas. These cells are CD43-positive. - B-1 B lymphocyte - B-1 B-cell - B-1 B-lymphocyte - B-1 cell - B1 B cell - B1 B lymphocyte - B1 B-cell - B1 B-lymphocyte - B1 cell - cell - There are small numbers of B-1 cells found in the lymph nodes and spleen, while larger numbers can be found in the peritoneal and pleural cavities. B-1 B cells are reportedly CD11b-positive, CD20-positive, CD21-positive, CD27-positive, CD44-positive, CD45RB-positive, CD48-positive, CD70-negative, CD150-positive, CD244-negative, CD352-positive, sIgM-positive, and sIgD-low. - B-1 B cell - - - - - A B cell of distinct lineage and surface marker expression. B-1 B cells are thought to be the primary source of natural IgM immunoglobulin, that is, IgM produced in large quantities without prior antigenic stimulation and generally reactive against various microorganisms, as well as the source of T-independent IgA immunoglobulin in the mucosal areas. These cells are CD43-positive. - GOC:add - GOC:dsd - GO_REF:0000031 - PMID:11861604 - PMID:20933013 - PMID:21220451 - http://en.wikipedia.org/wiki/B-1_cell - + @@ -15528,28 +6556,7 @@ radial glial cells acting as neural progenitors throughout life. - A B-1 B cell that has the phenotype CD5-positive. - B-1a B lymphocyte - B-1a B-cell - B-1a B-lymphocyte - B1a B cell - B1a B lymphocyte - B1a B-cell - B1a B-lymphocyte - B1a cell - CD5(+) B1 cell - CD5+ B1 cell - CD5-positive B1 cell - cell - B-1a B cell - - - - - A B-1 B cell that has the phenotype CD5-positive. - GOC:add - PMID:11861604 - + @@ -15557,25 +6564,7 @@ radial glial cells acting as neural progenitors throughout life. - A B-1 B cell that has the phenotype CD5-negative, but having other phenotypic attributes of a B-1 B cell. - B-1b B lymphocyte - B-1b B-cell - B-1b B-lymphocyte - B1b B cell - B1b B lymphocyte - B1b B-cell - B1b B-lymphocyte - B1b cell - cell - B-1b B cell - - - - - A B-1 B cell that has the phenotype CD5-negative, but having other phenotypic attributes of a B-1 B cell. - GOC:add - PMID:11861604 - + @@ -15583,31 +6572,7 @@ radial glial cells acting as neural progenitors throughout life. - A conventional B cell subject to antigenic stimulation and dependent on T cell help and with a distinct surface marker expression pattern from B-1 B cells. These cells are CD43-negative. - B-2 B lymphocyte - B-2 B-cell - B-2 B-lymphocyte - B2 B cell - B2 B lymphocyte - B2 B-cell - B2 B-lymphocyte - B2 cell - cell - B-0 B cell - B-2 B cells are reportedly CD48-positive, CD244-negative, and CD352-positive. - B-2 B cell - - - - - A conventional B cell subject to antigenic stimulation and dependent on T cell help and with a distinct surface marker expression pattern from B-1 B cells. These cells are CD43-negative. - GOC:add - GOC:dsd - GOC:tfm - ISBN:0781735149 - PMID:11861604 - PMID:20933013 - + @@ -15615,28 +6580,9 @@ radial glial cells acting as neural progenitors throughout life. - A natural killer cell that is developmentally immature and expresses natural killer cell receptors (NKR). - immature NK cell - cell - p-NK - In mouse the NKR are Ly49 molecules and in human these cells express KIR molecules. - immature natural killer cell - - - - - A natural killer cell that is developmentally immature and expresses natural killer cell receptors (NKR). - GOC:add - GO_REF:0000031 - ISBN:0781735149 - PMID:12457618 - - - - - p-NK - PMID:12457618 - + + + @@ -15644,34 +6590,9 @@ radial glial cells acting as neural progenitors throughout life. - A natural killer cell that is developmentally mature and expresses a variety of inhibitory and activating receptors that recognize MHC class I and other stress related molecules. - LAK cell - lymphokine activated killer cell - mature NK cell - cell - mature natural killer cell - - - - - A natural killer cell that is developmentally mature and expresses a variety of inhibitory and activating receptors that recognize MHC class I and other stress related molecules. - GOC:add - GO_REF:0000031 - ISBN:0781735149 - PMID:14685782 - - - - - LAK cell - PMID:14685782 - - - - - lymphokine activated killer cell - PMID:14685782 - + + + @@ -15679,48 +6600,7 @@ radial glial cells acting as neural progenitors throughout life. - A lymphoid progenitor cell that is committed to the natural killer cell lineage, expressing CD122 (IL-15) receptor, but lacking many of the phenotypic characteristics of later stages of natural killer cell development such as expression of NK activating and inhibitory molecules. In human this cell has the phenotype CD34-positive, CD45RA-positive, CD10-positive, CD117-negative, and CD161 negative. - NKP - natural killer cell progenitor - pro-natural killer cell - cell - null cell - preNK cell - Most markers only described for human pro NK cells. - pro-NK cell - - - - - A lymphoid progenitor cell that is committed to the natural killer cell lineage, expressing CD122 (IL-15) receptor, but lacking many of the phenotypic characteristics of later stages of natural killer cell development such as expression of NK activating and inhibitory molecules. In human this cell has the phenotype CD34-positive, CD45RA-positive, CD10-positive, CD117-negative, and CD161 negative. - GOC:add - GOC:pam - GO_REF:0000031 - PMID:11532393 - PMID:12457618 - PMID:15032583 - PMID:15766674 - - - - - NKP - PMID:12457618 - PMID:15032583 - PMID:15766674 - - - - - null cell - PMID:11532393 - - - - - preNK cell - PMID:11532393 - + @@ -15728,44 +6608,7 @@ radial glial cells acting as neural progenitors throughout life. - A progenitor cell of the B cell lineage, with some lineage specific activity such as early stages of recombination of B cell receptor genes, but not yet fully committed to the B cell lineage until the expression of PAX5 occurs. - pre-pro B cell - BTO:0003104 - pro-B lymphocyte - pro-B-cell - pro-B-lymphocyte - progenitor B cell - progenitor B lymphocyte - progenitor B-cell - progenitor B-lymphocyte - cell - pre-B cell (Philadelphia nomenclature) - Human pro-B cells are reportedly CD10-positive, CD22-positive, CD34-positive, CD38-positive, CD45-low, CD48-positive, CD79a-positive, CD127-positive, CD184-positive, RAG-positive, TdT-positive, Vpre-B-positive, pre-BCR-negative, IgD-negative, and IgM-negative. Transcription factors expressed: Pax5-positive, EBF-positive, E2A-negative, Ikaros-negative, and PU.1-negative. - pro-B cell - - - - - A progenitor cell of the B cell lineage, with some lineage specific activity such as early stages of recombination of B cell receptor genes, but not yet fully committed to the B cell lineage until the expression of PAX5 occurs. - GOC:add - GOC:dsd - ISBN:0781735149 - PMID:12633665 - PMID:16551251 - PMID:18432934 - - - - - pre-pro B cell - PMID:17582343 - - - - - pre-B cell (Philadelphia nomenclature) - PMID:11244048 - + @@ -15773,22 +6616,7 @@ radial glial cells acting as neural progenitors throughout life. - A lymphoid progenitor cell of the T cell lineage, with some lineage specific marker expression, but not yet fully committed to the T cell lineage. - pro-T lymphocyte - progenitor T cell - DN1 cell - DN1 thymocyte - TN1 cell - cell - pro-T cell - - - - A lymphoid progenitor cell of the T cell lineage, with some lineage specific marker expression, but not yet fully committed to the T cell lineage. - GOC:add - ISBN:0781735149 - @@ -15798,19 +6626,7 @@ radial glial cells acting as neural progenitors throughout life. - A progenitor cell of the thrombocyte, a nucleated blood cell involved in coagulation typically seen in birds and other non-mammalian vertebrates. - cell - Note that this is a non-mammalian cell type. - thromboblast - - - - A progenitor cell of the thrombocyte, a nucleated blood cell involved in coagulation typically seen in birds and other non-mammalian vertebrates. - GOC:add - GOC:tfm - PMID:7758949 - @@ -15818,17 +6634,7 @@ radial glial cells acting as neural progenitors throughout life. - A myeloblast committed to the basophil lineage. - cell - basophilic myeloblast - - - - A myeloblast committed to the basophil lineage. - GOC:add - ISBN:0721601464 - @@ -15836,18 +6642,7 @@ radial glial cells acting as neural progenitors throughout life. - A promyelocyte committed to the basophil lineage. - FMA:84208 - cell - basophilic promyelocyte - - - - A promyelocyte committed to the basophil lineage. - GOC:add - ISBN:0721601464 - @@ -15856,27 +6651,7 @@ radial glial cells acting as neural progenitors throughout life. - A progenitor cell of the mast cell lineage. Markers for this cell are FceRIa-low, CD117-positive, CD9-positive, T1/ST2-positive, SCA1-negative, and lineage-negative. - MCP - cell - CFU-MC - CFU-Mast - colony forming unit mast cell - MCP are CD16-positive, CD32-positive, CD34-positive, CD45-positive, integrin beta-7-positive, and lin-negative (CD2, CD3e, CD4, CD5, CD8a, CD14, CD19, CD20, CD27, integrin alpha-M, ly6c, ly6g, NCAM-1, and ter119). These cells also express the transcription factors GATA-1, GATA-2, and MITF, but not C/EBPa. - mast cell progenitor - - - - - A progenitor cell of the mast cell lineage. Markers for this cell are FceRIa-low, CD117-positive, CD9-positive, T1/ST2-positive, SCA1-negative, and lineage-negative. - GOC:add - GOC:dsd - PMCID:PMC1183570 - PMCID:PMC1312421 - PMID:8629001 - PMID:9354811 - http://www.copewithcytokines.de - + @@ -15884,17 +6659,7 @@ radial glial cells acting as neural progenitors throughout life. - A myeloblast committed to the eosinophil lineage. - cell - eosinophilic myeloblast - - - - A myeloblast committed to the eosinophil lineage. - GOC:add - ISBN:0721601464 - @@ -15902,18 +6667,7 @@ radial glial cells acting as neural progenitors throughout life. - A promyelocyte committed to the eosinophil lineage. - FMA:84199 - cell - eosinophilic promyelocyte - - - - A promyelocyte committed to the eosinophil lineage. - GOC:add - ISBN:0721601464 - @@ -15922,19 +6676,7 @@ radial glial cells acting as neural progenitors throughout life. - A progenitor cell of the neutrophil lineage. - cell - neutrophil stem cell - neutrophil progenitor cell - - - - A progenitor cell of the neutrophil lineage. - GOC:add - GOC:tfm - ISBN:0721601464 - @@ -15944,21 +6686,7 @@ radial glial cells acting as neural progenitors throughout life. - The most primitive precursor in the granulocytic series, having fine, evenly distributed chromatin, several nucleoli, a high nuclear-to-cytoplasmic ration (5:1-7:1), and a nongranular basophilic cytoplasm. They reside in the bone marrow. - BTO:0000187 - FMA:83524 - cell - myeloblast - - - - The most primitive precursor in the granulocytic series, having fine, evenly distributed chromatin, several nucleoli, a high nuclear-to-cytoplasmic ration (5:1-7:1), and a nongranular basophilic cytoplasm. They reside in the bone marrow. - GOC:add - ISBN:0721601464 - http://en.wikipedia.org/wiki/Myeloblast - http://www.cap.org - @@ -15968,22 +6696,7 @@ radial glial cells acting as neural progenitors throughout life. - A precursor in the granulocytic series, being a cell intermediate in development between a myeloblast and myelocyte, that has distinct nucleoli, a nuclear-to-cytoplasmic ratio of 5:1 to 3:1, and containing a few primary cytoplasmic granules. Markers for this cell are fucosyltransferase FUT4-positive, CD33-positive, integrin alpha-M-negative, low affinity immunoglobulin gamma Fc region receptor III-negative, and CD24-negative. - CALOHA:TS-0825 - FMA:83530 - cell - promyelocyte - - - - A precursor in the granulocytic series, being a cell intermediate in development between a myeloblast and myelocyte, that has distinct nucleoli, a nuclear-to-cytoplasmic ratio of 5:1 to 3:1, and containing a few primary cytoplasmic granules. Markers for this cell are fucosyltransferase FUT4-positive, CD33-positive, integrin alpha-M-negative, low affinity immunoglobulin gamma Fc region receptor III-negative, and CD24-negative. - GOC:add - GOC:amm - GOC:tfm - ISBN:0721601464 - http://www.cap.org - @@ -15991,23 +6704,8 @@ radial glial cells acting as neural progenitors throughout life. - A hematopoietic multipotent progenitor cell is multipotent, but not capable of long-term self-renewal. These cells are characterized as lacking lineage cell surface markers and being CD34-positive in both mice and humans. - BTO:0000725 - CALOHA:TS-0448 - MPP - hemopoietic progenitor cell - cell - Markers differ between mouse and human. - hematopoietic multipotent progenitor cell - - - - - A hematopoietic multipotent progenitor cell is multipotent, but not capable of long-term self-renewal. These cells are characterized as lacking lineage cell surface markers and being CD34-positive in both mice and humans. - GOC:add - GOC:tfm - PMID:19022770 - + + @@ -16016,22 +6714,8 @@ radial glial cells acting as neural progenitors throughout life. - A progenitor cell restricted to the lymphoid lineage. - lymphoid progenitor cell - BTO:0004731 - CALOHA:TS-2025 - FMA:70338 - cell - Note that this is a class of cell types, not an identified single cell type. - lymphoid lineage restricted progenitor cell + - - - - A progenitor cell restricted to the lymphoid lineage. - GOC:add - GOC:tfm - @@ -16040,23 +6724,7 @@ radial glial cells acting as neural progenitors throughout life. - A progenitor cell restricted to the myeloid lineage. - myeloid progenitor cell - BTO:0004730 - CALOHA:TS-2099 - FMA:70339 - cell - Note that this is a class of cell types, not an identified single cell type. - myeloid lineage restricted progenitor cell - - - - - A progenitor cell restricted to the myeloid lineage. - GOC:add - GOC:tfm - PMID:19022770 - + @@ -16065,19 +6733,7 @@ radial glial cells acting as neural progenitors throughout life. - An immature cell of the conventional dendritic cell lineage, characterized by high levels of antigen uptake via endocytosis, macropinocytosis, and phagocytosis, and typically found resident in the tissues. Markers for this cell are CD80-low, CD86-low, and MHC-II-low. - immature myeloid dendritic cell - cell - immature conventional dendritic cell - - - - An immature cell of the conventional dendritic cell lineage, characterized by high levels of antigen uptake via endocytosis, macropinocytosis, and phagocytosis, and typically found resident in the tissues. Markers for this cell are CD80-low, CD86-low, and MHC-II-low. - GOC:add - GOC:tfm - PMID:9521319 - @@ -16086,27 +6742,7 @@ radial glial cells acting as neural progenitors throughout life. - A mature cell of the conventional dendritic cell lineage, characterized by a high capacity for antigen presentation and typically found in a lymph node. - mature dendritic cell - FMA:83038 - mature myeloid dendritic cell - cell - mature conventional dendritic cell - - - - - A mature cell of the conventional dendritic cell lineage, characterized by a high capacity for antigen presentation and typically found in a lymph node. - GOC:add - GOC:tfm - PMID:9521319 - - - - - mature dendritic cell - GOC:add - + @@ -16115,21 +6751,7 @@ radial glial cells acting as neural progenitors throughout life. - A leukocyte with a single non-segmented nucleus in the mature form. - BTO:0000878 - CALOHA:TS-0768 - FMA:86713 - mononuclear leukocyte - peripheral blood mononuclear cell - cell - mononuclear cell - - - - A leukocyte with a single non-segmented nucleus in the mature form. - GOC:add - @@ -16137,27 +6759,7 @@ radial glial cells acting as neural progenitors throughout life. - A resting mature B cell that has the phenotype IgM-positive, IgD-positive, CD23-positive and CD21-positive, and found in the B cell follicles of the white pulp of the spleen or the corticol areas of the peripheral lymph nodes. This cell type is also described as being CD19-positive, B220-positive, AA4-negative, CD43-negative, and CD5-negative. - Fo B cell - Fo B-cell - follicular B lymphocyte - follicular B-cell - follicular B-lymphocyte - cell - Follicular B cells are also reportedly CD48-positive, CD84-positive, CD229-positive, and CD352-positive. - follicular B cell - - - - - A resting mature B cell that has the phenotype IgM-positive, IgD-positive, CD23-positive and CD21-positive, and found in the B cell follicles of the white pulp of the spleen or the corticol areas of the peripheral lymph nodes. This cell type is also described as being CD19-positive, B220-positive, AA4-negative, CD43-negative, and CD5-negative. - GOC:add - GOC:dsd - ISBN:0781735149 - PMCID:PMC2193793 - PMID:20933013 - http://en.wikipedia.org/wiki/Follicular_B_Cells - + @@ -16165,29 +6767,7 @@ radial glial cells acting as neural progenitors throughout life. - A rapidly cycling mature B cell that has distinct phenotypic characteristics and is involved in T-dependent immune responses and located typically in the germinal centers of lymph nodes. This cell type expresses Ly77 after activation. - GC B cell - GC B lymphocyte - GC B-cell - GC B-lymphocyte - germinal center B lymphocyte - germinal center B-cell - germinal center B-lymphocyte - cell - Germinal center B cells are also reportedly CD10-positive, CD19-positive, CD20-positive, CD38-positive, CD44-low, CD45-positive, CD48-positive, CD95-positive, CD352-positive, and HLA-DR-positive. Transcription factors: BCL6-positive, Ets1-positive, IRF8-positive, MTA3-positive, OBF1-positive, PAX5-positive, SpiB-positive, and STAT3-positive. - germinal center B cell - - - - - A rapidly cycling mature B cell that has distinct phenotypic characteristics and is involved in T-dependent immune responses and located typically in the germinal centers of lymph nodes. This cell type expresses Ly77 after activation. - GOC:add - GOC:dsd - GOC:tfm - ISBN:0781735149 - PMID:19447676 - PMID:20933013 - + @@ -16196,29 +6776,7 @@ radial glial cells acting as neural progenitors throughout life. - A mature B cell that is located in the marginal zone of the spleen with the phenotype CD23-negative and CD21-positive and expressing a B cell receptor usually reactive to bacterial cell wall components or senescent self components such as oxidized-LDL. This cell type is also described as being CD19-positive, B220-positive, IgM-high, AA4-negative, CD35-high. - MZ B cell - MZ B lymphocyte - MZ B-cell - MZ B-lymphocyte - marginal zone B lymphocyte - marginal zone B-cell - marginal zone B-lymphocyte - cell - MZ B cells are reportedly CD1-positive (mice), CD20-positive, CD48-positive, CD84-positive, CD150-positive, CD229-positive, and CD352-positive. - marginal zone B cell - - - - - A mature B cell that is located in the marginal zone of the spleen with the phenotype CD23-negative and CD21-positive and expressing a B cell receptor usually reactive to bacterial cell wall components or senescent self components such as oxidized-LDL. This cell type is also described as being CD19-positive, B220-positive, IgM-high, AA4-negative, CD35-high. - GOC:add - GOC:dsd - ISBN:0781735149 - PMID:10933592 - PMID:20933013 - http://en.wikipedia.org/wiki/Marginal-zone_B_cell - + @@ -16227,16 +6785,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell of the vestibular sensory organ that is characterized by intense enzymatic activities and numerous basal membrane infoldings. - cell - vestibular dark cell - - - - An epithelial cell of the vestibular sensory organ that is characterized by intense enzymatic activities and numerous basal membrane infoldings. - PMID:11223304 - @@ -16245,18 +6794,7 @@ radial glial cells acting as neural progenitors throughout life. - An olfactory receptor cell in which the apical ending of the dendrite is a pronounced ciliated olfactory knob. - ciliated olfactory sensory neuron - ciliated sensory neuron - cell - ciliated olfactory receptor neuron - - - - An olfactory receptor cell in which the apical ending of the dendrite is a pronounced ciliated olfactory knob. - PMID:16841163 - @@ -16264,18 +6802,7 @@ radial glial cells acting as neural progenitors throughout life. - An olfactory receptor cell in which the apical ending of the dendrite is a knob that bears numerous microvilli. - microvillous olfactory sensory neuron - cell - microvillous sensory neuron - microvillous olfactory receptor neuron - - - - An olfactory receptor cell in which the apical ending of the dendrite is a knob that bears numerous microvilli. - PMID:16841163 - @@ -16283,19 +6810,7 @@ radial glial cells acting as neural progenitors throughout life. - An olfactory receptor cell with short cilia growing in an invagination bordered by microvilli. - crypt cell - crypt olfactory sensory neuron - crypt sensory neuron - cell - crypt olfactory receptor neuron - - - - An olfactory receptor cell with short cilia growing in an invagination bordered by microvilli. - PMID:16841163 - @@ -16304,22 +6819,7 @@ radial glial cells acting as neural progenitors throughout life. - A neuron that releases serotonin as a neurotransmitter. - CL:0000403 - FBbt:00005133 - WBbt:0006837 - 5-HT neuron - 5-hydroxytryptamine neuron - cell - serotinergic neuron - serotonergic neuron - - - - A neuron that releases serotonin as a neurotransmitter. - SANBI:mhl - @@ -16327,16 +6827,8 @@ radial glial cells acting as neural progenitors throughout life. - Neuromast mantle cell is a non-sensory cell. Neuromast mantle cells surround the neuromast support cells and neuromast hair cells, separating the neuromast from the epidermis, and secrete cupula in which the ciliary bundles of all the hair cells are embedded. - cell - neuromast mantle cell + - - - - Neuromast mantle cell is a non-sensory cell. Neuromast mantle cells surround the neuromast support cells and neuromast hair cells, separating the neuromast from the epidermis, and secrete cupula in which the ciliary bundles of all the hair cells are embedded. - ISBN:0125296509 - @@ -16344,16 +6836,8 @@ radial glial cells acting as neural progenitors throughout life. - Neuromast support cell is a non-sensory cell of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; neuromast support cells are surrounded by neuromast mantle cells. - cell - neuromast support cell + - - - - Neuromast support cell is a non-sensory cell of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; neuromast support cells are surrounded by neuromast mantle cells. - ISBN:0125296509 - @@ -16362,22 +6846,7 @@ radial glial cells acting as neural progenitors throughout life. - Olfactory epithelial support cell is a columnar cell that extends from the epithelial free margin to the basement membrane of the olfactory epithelium. This cell type has a large, vertically, elongate, euchromatic nucleus, along with other nuclei, forms a layer superficial to the cell body of the receptor cell; sends long somewhat irregular microvilli into the mucus layer; at the base, with expanded end-feet containing numerous lamellated dense bodies resembling lipofuscin of neurons. - FMA:62302 - olfactory sustentacular cell - supporting cell of olfactory epithelium - sustentaculocyte of olfactory epithelium - cell - olfactory epithelial support cell - - - - Olfactory epithelial support cell is a columnar cell that extends from the epithelial free margin to the basement membrane of the olfactory epithelium. This cell type has a large, vertically, elongate, euchromatic nucleus, along with other nuclei, forms a layer superficial to the cell body of the receptor cell; sends long somewhat irregular microvilli into the mucus layer; at the base, with expanded end-feet containing numerous lamellated dense bodies resembling lipofuscin of neurons. - GOC:tfm - ISBN:0517223651 - SANBI:mhl - @@ -16385,16 +6854,7 @@ radial glial cells acting as neural progenitors throughout life. - Interneuromast cell is a neuroectodermal cell deposited by the migrating lateral line primordium between the neuromasts. Interneuromast cells proliferate and migrate to form additional neuromasts. - cell - interneuromast cell - - - - Interneuromast cell is a neuroectodermal cell deposited by the migrating lateral line primordium between the neuromasts. Interneuromast cells proliferate and migrate to form additional neuromasts. - SANBI:mhl - @@ -16402,18 +6862,7 @@ radial glial cells acting as neural progenitors throughout life. - Hair cell is a mechanoreceptor cell that is sensitive to movement of the hair-like projections (stereocilia and kinocilia) which relay the information centrally in the nervous system. - hair cell - BTO:0004744 - cell - sensory hair cell - - - - Hair cell is a mechanoreceptor cell that is sensitive to movement of the hair-like projections (stereocilia and kinocilia) which relay the information centrally in the nervous system. - SANBI:mhl - @@ -16421,16 +6870,7 @@ radial glial cells acting as neural progenitors throughout life. - Neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. - cell - neuromast hair cell - - - - Neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. - SANBI:mhl - @@ -16438,16 +6878,7 @@ radial glial cells acting as neural progenitors throughout life. - A skeletal muscle myoblast that differentiates into slow muscle fibers. - cell - slow muscle myoblast - - - - A skeletal muscle myoblast that differentiates into slow muscle fibers. - SANBI:mhl - @@ -16455,16 +6886,7 @@ radial glial cells acting as neural progenitors throughout life. - A skeletal muscle myoblast that differentiates into fast muscle fibers. - cell - fast muscle myoblast - - - - A skeletal muscle myoblast that differentiates into fast muscle fibers. - SANBI:mhl - @@ -16473,23 +6895,7 @@ radial glial cells acting as neural progenitors throughout life. - A monocyte that responds rapidly to microbial stimuli by secreting cytokines and antimicrobial factors and which is characterized by high expression of CCR2 in both rodents and humans, negative for the lineage markers CD3, CD19, and CD20, and of larger size than non-classical monocytes. - inflammatory monocyte - cell - Markers: CCR2+CXCCR1<low> (human, mouse, rat). - classical monocyte - - - - - A monocyte that responds rapidly to microbial stimuli by secreting cytokines and antimicrobial factors and which is characterized by high expression of CCR2 in both rodents and humans, negative for the lineage markers CD3, CD19, and CD20, and of larger size than non-classical monocytes. - GOC:add - GO_REF:0000031 - PMID:16322748 - PMID:18303997 - PMID:20628149 - PMID:20870168 - + @@ -16497,25 +6903,7 @@ radial glial cells acting as neural progenitors throughout life. - A macrophage which develops from an inflammatory monocyte and is recruited into the tissues in response to injury and infection as part of an inflammatory response. Markers include CD11b-positive, CD68-positive, and F4/80-positive. - FMA:84643 - FMA:84645 - free macrophage - wandering histiocyte - cell - Markers: CD11b+, CD68+; Mouse: F4/80+; role or process: immune, inflammation (inflammatory response). - elicited macrophage - - - - - A macrophage which develops from an inflammatory monocyte and is recruited into the tissues in response to injury and infection as part of an inflammatory response. Markers include CD11b-positive, CD68-positive, and F4/80-positive. - GOC:add - GOC:ana - GOC:tfm - GO_REF:0000031 - PMID:15771589 - + @@ -16523,19 +6911,7 @@ radial glial cells acting as neural progenitors throughout life. - A macrophage that suppresses immune responses. - cell - Markers: May express: IL10, TGFbeta. - suppressor macrophage - - - - A macrophage that suppresses immune responses. - GOC:add - GOC:tfm - PMID:20402419 - @@ -16543,21 +6919,7 @@ radial glial cells acting as neural progenitors throughout life. - An elicited macrophage that is recruited into the tissues in response to injury and infection as part of an inflammatory response, expresses high levels of pro-inflammatory cytokines, ROS and NO, and shows potent microbicidal activity. - classically activated macrophage - cell - M1 macrophage - Markers: Express: TNFa, IL1b, IL6, iNOS, NADPH-oxidase; produce: reactive oxygen species, nitric oxide; role or process: immune, inflammation (inflammatory response). - inflammatory macrophage - - - - An elicited macrophage that is recruited into the tissues in response to injury and infection as part of an inflammatory response, expresses high levels of pro-inflammatory cytokines, ROS and NO, and shows potent microbicidal activity. - GOC:ana - GO_REF:0000031 - PMID:19132917 - @@ -16565,22 +6927,7 @@ radial glial cells acting as neural progenitors throughout life. - A macrophage constitutively resident in a particular tissue under non-inflammatory conditions, and capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells. - FMA:84642 - FMA:84644 - fixed macrophage - resting histiocyte - cell - tissue-resident macrophage - - - - A macrophage constitutively resident in a particular tissue under non-inflammatory conditions, and capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells. - GOC:ana - GO_REF:0000031 - PMID:19770654 - @@ -16588,18 +6935,7 @@ radial glial cells acting as neural progenitors throughout life. - A gut-associated lymphoid tissue macrophage found in lamina propria of the gut. - cell - gastrointestinal tract (lamina propria) macrophage - - - - A gut-associated lymphoid tissue macrophage found in lamina propria of the gut. - GOC:ana - GOC:tfm - GO_REF:0000031 - @@ -16607,20 +6943,7 @@ radial glial cells acting as neural progenitors throughout life. - A tissue-resident macrophage resident found in the thymus, involved in the clearance of apoptotic thymocytes. - cell - Role or process: immune, clearance of apoptotic thymocytes, antigen-presentation. - thymic macrophage - - - - A tissue-resident macrophage resident found in the thymus, involved in the clearance of apoptotic thymocytes. - GOC:ana - GOC:tfm - GO_REF:0000031 - PMID:9048205 - @@ -16628,18 +6951,7 @@ radial glial cells acting as neural progenitors throughout life. - A tissue-resident macrophage found in a secondary lymphoid organ. - cell - secondary lymphoid organ macrophage - - - - A tissue-resident macrophage found in a secondary lymphoid organ. - GOC:ana - GOC:tfm - GO_REF:0000031 - @@ -16647,21 +6959,7 @@ radial glial cells acting as neural progenitors throughout life. - A secondary lymphoid organ macrophage found in a lymph node. This cell is CD169-high. - MF.LN - cell - Marker was observed on rat cells. - lymph node macrophage - - - - A secondary lymphoid organ macrophage found in a lymph node. This cell is CD169-high. - GOC:ana - GOC:tfm - GO_REF:0000031 - PMID:11971865 - @@ -16669,18 +6967,7 @@ radial glial cells acting as neural progenitors throughout life. - A gut-associated lymphoid tissue macrophage found in tonsils. - cell - tonsillar macrophage - - - - A gut-associated lymphoid tissue macrophage found in tonsils. - GOC:ana - GO_REF:0000031 - PMID:16048540 - @@ -16688,18 +6975,7 @@ radial glial cells acting as neural progenitors throughout life. - A gut-associated lymphoid tissue macrophage found in the Peyer's patches. - cell - Peyer's patch macrophage - - - - A gut-associated lymphoid tissue macrophage found in the Peyer's patches. - GOC:ana - GOC:tfm - GO_REF:0000031 - @@ -16708,20 +6984,7 @@ radial glial cells acting as neural progenitors throughout life. - A secondary lymphoid organ macrophage found in the spleen. - FMA:83026 - cell - Role or process: immune, clearance of apoptotic and senescent cells. - splenic macrophage - - - - A secondary lymphoid organ macrophage found in the spleen. - GO_REF:0000031 - PMID:15771589 - PMID:16322748 - @@ -16729,19 +6992,7 @@ radial glial cells acting as neural progenitors throughout life. - A splenic macrophage found in the marginal zone of the spleen, involved in recognition and clearance of particulate material from the splenic circulation. Markers include F4/80-negative, MARCO-positive, SR-A-positive, SIGN-R1-positive, and Dectin2-positive. - cell - Markers: Mouse: F4/80-, MARCO+, SR-A+, SIGN-R1+, Dectin2+. - splenic marginal zone macrophage - - - - A splenic macrophage found in the marginal zone of the spleen, involved in recognition and clearance of particulate material from the splenic circulation. Markers include F4/80-negative, MARCO-positive, SR-A-positive, SIGN-R1-positive, and Dectin2-positive. - GOC:ana - GO_REF:0000031 - PMID:16861066 - @@ -16749,19 +7000,7 @@ radial glial cells acting as neural progenitors throughout life. - A splenic macrophage found in the areas surrounding the white pulp of the spleen, adjacent to the marginal sinus. Markers include F4/80-negative, Dectin2-low, sialoadhesin-positive. - cell - Markers: Mouse: F4/80-, Dectin2-low, sialoadhesin+. - splenic metallophillic macrophage - - - - A splenic macrophage found in the areas surrounding the white pulp of the spleen, adjacent to the marginal sinus. Markers include F4/80-negative, Dectin2-low, sialoadhesin-positive. - GOC:ana - GO_REF:0000031 - PMID:20018690 - @@ -16769,19 +7008,7 @@ radial glial cells acting as neural progenitors throughout life. - A splenic macrophage found in the red-pulp of the spleen, and involved in immune responses to blood-borne pathogens and in the clearance of senescent erythrocytes. Markers include F4/80-positive, CD68-positive, MR-positive, Dectin2-positive, macrosialin-positive, and sialoadhesin-low. - cell - Markers: Mouse: F4/80+, CD68+, MR+, Dectin2+, macrosialin+, sialoadhesin-low; role or process: immune, clearance of senescent erythrocytes. - splenic red pulp macrophage - - - - A splenic macrophage found in the red-pulp of the spleen, and involved in immune responses to blood-borne pathogens and in the clearance of senescent erythrocytes. Markers include F4/80-positive, CD68-positive, MR-positive, Dectin2-positive, macrosialin-positive, and sialoadhesin-low. - GOC:ana - GO_REF:0000031 - PMID:19644016 - @@ -16789,24 +7016,7 @@ radial glial cells acting as neural progenitors throughout life. - A type of monocyte characterized by low expression of CCR2, low responsiveness to monocyte chemoattractant CCL2/MCP1, low phagocytic activity, and decrease size relative to classical monocytes, but increased co-stimulatory activity. May also play a role in tissue repair. - patrolling monocyte - resident monocyte - cell - Markers: CCR2-CX3CCR1+ (human, mouse, rat); human: CD16+, CCR5+, CD32/FcgRII-high, MHCII+, CD86+; mouse: CD62L-Ly6C-. - non-classical monocyte - - - - - A type of monocyte characterized by low expression of CCR2, low responsiveness to monocyte chemoattractant CCL2/MCP1, low phagocytic activity, and decrease size relative to classical monocytes, but increased co-stimulatory activity. May also play a role in tissue repair. - GOC:add - GO_REF:0000031 - PMID:16322748 - PMID:18303997 - PMID:20628149 - PMID:20870168 - + @@ -16814,19 +7024,7 @@ radial glial cells acting as neural progenitors throughout life. - A splenic macrophage found in the white pulp of the spleen. Markers include F4/80-negative, CD68-positive, and macrosialin-positive. - cell - Markers: Mouse: F4/80-, CD68+, macrosialin+. - splenic white pulp macrophage - - - - A splenic macrophage found in the white pulp of the spleen. Markers include F4/80-negative, CD68-positive, and macrosialin-positive. - GOC:ana - GO_REF:0000031 - PMID:11207597 - @@ -16834,19 +7032,7 @@ radial glial cells acting as neural progenitors throughout life. - A splenic white pulp macrophage found in and around the germinal centers of the white pulp of the spleen that participates in phagocytosis of apoptotic B cells from the germinal centers. A marker for a cell of this type is Mertk-positive. - cell - splenic tingible body macrophage - - - - A splenic white pulp macrophage found in and around the germinal centers of the white pulp of the spleen that participates in phagocytosis of apoptotic B cells from the germinal centers. A marker for a cell of this type is Mertk-positive. - GOC:ana - GOC:tfm - GO_REF:0000031 - PMID:19631584 - @@ -16855,18 +7041,7 @@ radial glial cells acting as neural progenitors throughout life. - A tissue-resident macrophage found in the central nervous system. - CNS macrophage - cell - central nervous system macrophage - - - - A tissue-resident macrophage found in the central nervous system. - GO_REF:0000031 - PMID:16322748 - @@ -16874,18 +7049,7 @@ radial glial cells acting as neural progenitors throughout life. - A central nervous system macrophage found in the meninges (the three membranes that surround the brain). This macrophage types is highly phagocytic and expresses scavenger receptors. - cell - meningeal macrophage - - - - A central nervous system macrophage found in the meninges (the three membranes that surround the brain). This macrophage types is highly phagocytic and expresses scavenger receptors. - GOC:ana - GO_REF:0000031 - PMID:11591794 - @@ -16893,18 +7057,7 @@ radial glial cells acting as neural progenitors throughout life. - A central nervous system macrophage found at the interface between the blood and the cerebrospinal fluid in the brain. This cell expresses scavenger receptors. - cell - choroid-plexus macrophage - - - - A central nervous system macrophage found at the interface between the blood and the cerebrospinal fluid in the brain. This cell expresses scavenger receptors. - GOC:ana - GO_REF:0000031 - PMID:9550136 - @@ -16912,19 +7065,7 @@ radial glial cells acting as neural progenitors throughout life. - A central nervous system macrophage found in small blood vessels in the brain. Markers include CD14+CD16+CD163+. - cell - Markers: Human/monkey, mice: CD163. Human: CD14+CD16+CD163+. - perivascular macrophage - - - - A central nervous system macrophage found in small blood vessels in the brain. Markers include CD14+CD16+CD163+. - GOC:tfm - GO_REF:0000031 - PMID:16507898 - @@ -16932,18 +7073,7 @@ radial glial cells acting as neural progenitors throughout life. - A thymic macrophage found in the thymic medulla. - cell - thymic medullary macrophage - - - - A thymic macrophage found in the thymic medulla. - GOC:ana - GO_REF:0000031 - PMID:9048205 - @@ -16951,19 +7081,7 @@ radial glial cells acting as neural progenitors throughout life. - A thymic macrophage found in the thymic cortex. - cell - thymic cortical macrophage - - - - A thymic macrophage found in the thymic cortex. - GOC:ana - GOC:tfm - GO_REF:0000031 - PMID:9048205 - @@ -16971,19 +7089,7 @@ radial glial cells acting as neural progenitors throughout life. - A tissue-resident macrophage found in the mucosa associated lymphoid tissue. - cell - mucosa-associated lymphoid tissue macrophage - - - - A tissue-resident macrophage found in the mucosa associated lymphoid tissue. - GOC:ana - GOC:tfm - GO_REF:0000031 - PMID:19906191 - @@ -16991,18 +7097,7 @@ radial glial cells acting as neural progenitors throughout life. - A mucosa-associated lymphoid tissue macrophage found in the mucosa-associated lymphoid tissues of the gut. - cell - gut-associated lymphoid tissue macrophage - - - - A mucosa-associated lymphoid tissue macrophage found in the mucosa-associated lymphoid tissues of the gut. - GOC:ana - GO_REF:0000031 - PMID:19906191 - @@ -17010,18 +7105,7 @@ radial glial cells acting as neural progenitors throughout life. - A mucosa-associated lymphoid tissue macrophage found in the nasal and bronchial mucosa-associated lymphoid tissues. - cell - nasal and broncial associated lymphoid tissue macrophage - - - - A mucosa-associated lymphoid tissue macrophage found in the nasal and bronchial mucosa-associated lymphoid tissues. - GOC:ana - GO_REF:0000031 - PMID:16048540 - @@ -17029,20 +7113,7 @@ radial glial cells acting as neural progenitors throughout life. - A lymph node macrophage found in the subcapsular sinus of lymph nodes that participates in sensing, clearance, and antigen presentation of lymph-borne particulate antigens. This macrophage is capable of activating invaraint NKT cells and is CD169-positive. - cell - lymph node subcapsular sinus macrophage - - - - A lymph node macrophage found in the subcapsular sinus of lymph nodes that participates in sensing, clearance, and antigen presentation of lymph-borne particulate antigens. This macrophage is capable of activating invaraint NKT cells and is CD169-positive. - GOC:tfm - GO_REF:0000031 - PMID:14668803 - PMID:17934446 - PMID:20228797 - @@ -17050,19 +7121,7 @@ radial glial cells acting as neural progenitors throughout life. - A lymph node macrophage found in the cortex of lymph nodes, in particular in and around the germinal centers, and that participates in phagocytosis of apoptotic B cells from the germinal centers. - cell - lymph node tingible body macrophage - - - - A lymph node macrophage found in the cortex of lymph nodes, in particular in and around the germinal centers, and that participates in phagocytosis of apoptotic B cells from the germinal centers. - GOC:ana - GOC:tfm - GO_REF:0000031 - PMID:19631584 - @@ -17070,22 +7129,7 @@ radial glial cells acting as neural progenitors throughout life. - An immature myeloid leukocyte of heterogeneous phenotype found particularly in cancer and sepsis patients that is capable of suppressing activity of T cells in ex vivo assays. This cell type is CD45-positive, CD11b-positive. - cell - Markers: Mouse: CD11b+GR1+CD31+; Human: CD34+ CD33+CD15-CD13+. (According to some reports in humans these cells are iNOS+ARG1+IL13+IFNg+); location: In cancerous tissue; in the blood and lymphoid organs in sepsis. - myeloid suppressor cell - - - - An immature myeloid leukocyte of heterogeneous phenotype found particularly in cancer and sepsis patients that is capable of suppressing activity of T cells in ex vivo assays. This cell type is CD45-positive, CD11b-positive. - GOC:add - GOC:ana - GO_REF:0000031 - PMID:16168663 - PMID:17016554 - PMID:17016559 - @@ -17093,21 +7137,7 @@ radial glial cells acting as neural progenitors throughout life. - An elicited macrophage characterized by low production of pro-inflammatory and Th1 polarizing cytokines and high expression of arginase-1, and associated with tissue remodelling. - cell - M2 macrophage - Role or process: tissue remodeling. - alternatively activated macrophage - - - - An elicited macrophage characterized by low production of pro-inflammatory and Th1 polarizing cytokines and high expression of arginase-1, and associated with tissue remodelling. - GOC:ana - GOC:tfm - GO_REF:0000031 - PMID:20510870 - @@ -17115,18 +7145,7 @@ radial glial cells acting as neural progenitors throughout life. - A type of cell containing lipids in small vacuoles and typically seen in atherolosclerotic lesions, as well as other conditions. - BTO:0003872 - FMA:83586 - cell - foam cell - - - - A type of cell containing lipids in small vacuoles and typically seen in atherolosclerotic lesions, as well as other conditions. - GOC:add - @@ -17134,16 +7153,7 @@ radial glial cells acting as neural progenitors throughout life. - A type of foam cell derived from a smooth muscle cell containing lipids in small vacuoles and typically seen in atherolosclerotic lesions, as well as other conditions. - cell - smooth muscle cell derived foam cell - - - - A type of foam cell derived from a smooth muscle cell containing lipids in small vacuoles and typically seen in atherolosclerotic lesions, as well as other conditions. - GOC:add - @@ -17151,28 +7161,7 @@ radial glial cells acting as neural progenitors throughout life. - An immature T cell located in the thymus. - immature T cell - immature T lymphocyte - immature T-cell - immature T-lymphocyte - BTO:0001372 - CALOHA:TS-1042 - FMA:72202 - XAO:0003159 - thymic lymphocyte - cell - thymocyte - - - - - An immature T cell located in the thymus. - GOC:add - GOC:tfm - GO_REF:0000031 - PMID:12415312 - + @@ -17180,25 +7169,7 @@ radial glial cells acting as neural progenitors throughout life. - A pro-T cell that has the phenotype CD4-negative, CD8-negative, CD44-positive, and CD25-negative. - DN1 thymic pro-T lymphocyte - DN1 thymic pro-T-cell - DN1 thymic pro-T-lymphocyte - DN1 thymic progenitor T cell - DN1 thymocyte - double negative 1 - preT.DN1.Th - cell - DN1 thymic pro-T cell - - - - - A pro-T cell that has the phenotype CD4-negative, CD8-negative, CD44-positive, and CD25-negative. - GOC:add - GOC:tfm - GO_REF:0000031 - + @@ -17207,40 +7178,7 @@ radial glial cells acting as neural progenitors throughout life. - An antigen inexperienced CD4-positive, alpha-beta T cell with the phenotype CCR7-positive, CD127-positive and CD62L-positive. This cell type develops in the thymus. This cell type is also described as being CD25-negative, CD62L-high, and CD44-low. - naive CD4+ T cell - T.4Nve.Sp - Th0 - naive thymus-derived CD4-positive, alpha-beta T lymphocyte - naive thymus-derived CD4-positive, alpha-beta T-cell - naive thymus-derived CD4-positive, alpha-beta T-lymphocyte - cell - These cells have not been exposed to antigen following thymic T-cell selection; found in blood and secondary lymphoid organs. This cell type is compatible with the HIPC Lyoplate markers for 'naive CD4+ T cell', but includes additional markers known to be expressed on naive CD4+ T cells. - naive thymus-derived CD4-positive, alpha-beta T cell - - - - - An antigen inexperienced CD4-positive, alpha-beta T cell with the phenotype CCR7-positive, CD127-positive and CD62L-positive. This cell type develops in the thymus. This cell type is also described as being CD25-negative, CD62L-high, and CD44-low. - GOC:add - GOC:tfm - GO_REF:0000031 - PMID:19100699 - PMID:22343568 - http://www.immgen.org/index_content.html - - - - - naive CD4+ T cell - PMID:22343568 - - - - - Th0 - GOC:tfm - + @@ -17248,21 +7186,7 @@ radial glial cells acting as neural progenitors throughout life. - A recently activated CD4-positive, alpha-beta T cell with the phenotype CD69-positive, CD62L-negative, CD127-negative, and CD25-positive. - activated CD4-positive, alpha-beta T lymphocyte - activated CD4-positive, alpha-beta T-cell - activated CD4-positive, alpha-beta T-lymphocyte - cell - activated CD4-positive, alpha-beta T cell - - - - A recently activated CD4-positive, alpha-beta T cell with the phenotype CD69-positive, CD62L-negative, CD127-negative, and CD25-positive. - GOC:add - GOC:pam - GO_REF:0000031 - @@ -17271,24 +7195,7 @@ radial glial cells acting as neural progenitors throughout life. - CD4-positive, alpha-beta long-lived T cell with the phenotype CD45RO-positive and CD127-positive. This cell type is also described as being CD25-negative, CD44-high, and CD122-high. - CD4-positive, alpha-beta memory T lymphocyte - CD4-positive, alpha-beta memory T-cell - CD4-positive, alpha-beta memory T-lymphocyte - cell - T4.Mem.Sp - CD4-positive, alpha-beta memory T cell - - - - - CD4-positive, alpha-beta long-lived T cell with the phenotype CD45RO-positive and CD127-positive. This cell type is also described as being CD25-negative, CD44-high, and CD122-high. - GOC:add - GOC:tfm - GO_REF:0000031 - ISBN:0781735149 - http://www.immgen.org/index_content.html - + @@ -17296,23 +7203,7 @@ radial glial cells acting as neural progenitors throughout life. - Mature T cell not yet exposed to antigen with the phenotype CCR7-positive, CD45RA-positive, and CD127-positive. This cell type is also described as being CD25-negative, CD62L-high and CD44-low. - naive T lymphocyte - naive T-cell - naive T-lymphocyte - cell - naive T cell - - - - - Mature T cell not yet exposed to antigen with the phenotype CCR7-positive, CD45RA-positive, and CD127-positive. This cell type is also described as being CD25-negative, CD62L-high and CD44-low. - GOC:add - GOC:pam - GOC:tfm - GO_REF:0000031 - PMID:19100699 - + @@ -17320,38 +7211,7 @@ radial glial cells acting as neural progenitors throughout life. - CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive, CXCR3-negative, CCR6-positive, and capable of producing IL-17. - IL-17-producing CD4+ T helper - T helper cells type 17 - T(H)-17 cell - Th17 CD4+ T cell - Th17 T cell - Th17 T lymphocyte - Th17 T-cell - Th17 T-lymphocyte - Th17 cell - helper T cell type 17 - cell - This cell type is compatible with the HIPC Lyoplate markers for 'Th17 CD4+ T cell', but its logical definition includes additional known characteristics of T-helper 17 T cells. - T-helper 17 cell - - - - - CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive, CXCR3-negative, CCR6-positive, and capable of producing IL-17. - GOC:add - GOC:pam - GO_REF:0000031 - PMID:20303875 - PMID:20969597 - PMID:22343568 - - - - - Th17 CD4+ T cell - PMID:22343568 - + @@ -17360,33 +7220,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD8-positive, alpha-beta T cell that has not experienced activation via antigen contact and has the phenotype CD45RA-positive, CCR7-positive and CD127-positive. This cell type is also described as being CD25-negative, CD62L-high and CD44-low. - naive CD8+ T cell - naive thymus-dervied CD8-positive, alpha-beta T lymphocyte - naive thymus-dervied CD8-positive, alpha-beta T-cell - naive thymus-dervied CD8-positive, alpha-beta T-lymphocyte - T.8Nve.Sp - cell - This cell traffics in secondary lymphoid organs and blood. This cell type is compatible with the HIPC Lyoplate markers for 'naive CD8+ T cell', but includes additional markers known to be expressed on naive CD8+ T cells. - naive thymus-derived CD8-positive, alpha-beta T cell - - - - - A CD8-positive, alpha-beta T cell that has not experienced activation via antigen contact and has the phenotype CD45RA-positive, CCR7-positive and CD127-positive. This cell type is also described as being CD25-negative, CD62L-high and CD44-low. - GOC:add - GOC:tfm - GO_REF:0000031 - ISBN:0781735149 - PMID:22343568 - http://www.immgen.org/index_content.html - - - - - naive CD8+ T cell - PMID:22343568 - + @@ -17395,25 +7229,7 @@ radial glial cells acting as neural progenitors throughout life. - CD4-positive alpha-beta T cell with regulatory function that produces IL-10. - T-regulatory T cell type 1 - Tr1 T cell - Tr1 T lymphocyte - Tr1 T-cell - Tr1 T-lymphocyte - cell - These cells are reportedly induced by IL-10 and are capable of producing IFN-gamma, IL-5, IL-10, and TGF-beta.) - Tr1 cell - - - - - CD4-positive alpha-beta T cell with regulatory function that produces IL-10. - GOC:add - GOC:pam - GO_REF:0000031 - PMID:16903904 - + @@ -17421,28 +7237,7 @@ radial glial cells acting as neural progenitors throughout life. - CD4-positive alpha-beta T cell with the phenotype CD25-positive, CTLA-4-positive, and FoxP3-positive with regulatory function. - iTreg - induced Treg - induced regulatory T cell - induced regulatory T lymphocyte - induced regulatory T-cell - induced regulatory T-lymphocyte - cell - aTreg - adaptive Treg - induced T-regulatory cell - - - - - CD4-positive alpha-beta T cell with the phenotype CD25-positive, CTLA-4-positive, and FoxP3-positive with regulatory function. - GOC:add - GOC:pam - GOC:tfm - GO_REF:0000031 - PMID:19464985 - + @@ -17450,26 +7245,7 @@ radial glial cells acting as neural progenitors throughout life. - CD4-positive alpha-beta T cell with the phenotype FoxP3-positive, CD25-positive, CD62L-positive, and CTLA-4 positive with regulatory function. - nTreg - natural Treg - natural regulatory T cell - natural regulatory T lymphocyte - natural regulatory T-cell - natural regulatory T-lymphocyte - cell - natural T-regulatory cell - - - - - CD4-positive alpha-beta T cell with the phenotype FoxP3-positive, CD25-positive, CD62L-positive, and CTLA-4 positive with regulatory function. - GOC:add - GOC:pam - GOC:tfm - GO_REF:0000031 - PMID:19464985 - + @@ -17477,34 +7253,7 @@ radial glial cells acting as neural progenitors throughout life. - CD4-positive, alpha-beta memory T cell with the phenotype CCR7-positive, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative. - central memory CD4+ T cell - central CD4-positive, alpha-beta memory T cell - central CD4-positive, alpha-beta memory T lymphocyte - central CD4-positive, alpha-beta memory T-cell - central CD4-positive, alpha-beta memory T-lymphocyte - central memory CD4-positive, alpha-beta T lymphocyte - central memory CD4-positive, alpha-beta T-cell - central memory CD4-positive, alpha-beta T-lymphocyte - cell - This cell type is compatible with the HIPC Lyoplate markers for 'central memory CD4+ T cell', but includes additional markers known to be expressed on central memory CD4+ T cells. - central memory CD4-positive, alpha-beta T cell - - - - - CD4-positive, alpha-beta memory T cell with the phenotype CCR7-positive, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative. - GOC:add - GOC:pam - GO_REF:0000031 - PMID:22343568 - - - - - central memory CD4+ T cell - PMID:22343568 - + @@ -17512,35 +7261,7 @@ radial glial cells acting as neural progenitors throughout life. - CD4-positive, alpha-beta memory T cell with the phenotype CCR7-negative, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative. - effector memory CD4+ T cell - effector CD4-positive, alpha-beta memory T cell - effector CD4-positive, alpha-beta memory T lymphocyte - effector CD4-positive, alpha-beta memory T-cell - effector CD4-positive, alpha-beta memory T-lymphocyte - effector memory CD4-positive, alpha-beta T lymphocyte - effector memory CD4-positive, alpha-beta T-cell - effector memory CD4-positive, alpha-beta T-lymphocyte - cell - This cell type is compatible with the HIPC Lyoplate markers for 'effector memory CD4+ T cell', but includes additional markers known to be expressed on effector memory CD4+ T cells. - effector memory CD4-positive, alpha-beta T cell - - - - - CD4-positive, alpha-beta memory T cell with the phenotype CCR7-negative, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative. - GOC:add - GOC:pam - GOC:tfm - GO_REF:0000031 - PMID:22343568 - - - - - effector memory CD4+ T cell - PMID:22343568 - + @@ -17548,22 +7269,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD8-positive, alpha-beta T cell with the phenotype CD69-positive, CD62L-negative, CD127-negative, CD25-positive, and CCR7-negative. - activated CD8-positive, alpha-beta T lymphocyte - activated CD8-positive, alpha-beta T-cell - activated CD8-positive, alpha-beta T-lymphocyte - cell - activated CD8-positive, alpha-beta T cell - - - - A CD8-positive, alpha-beta T cell with the phenotype CD69-positive, CD62L-negative, CD127-negative, CD25-positive, and CCR7-negative. - GOC:add - GOC:pam - GOC:tfm - GO_REF:0000031 - @@ -17571,36 +7277,7 @@ radial glial cells acting as neural progenitors throughout life. - CD8-positive, alpha-beta memory T cell with the phenotype CCR7-positive, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative. - central memory CD8+ T cell - central CD8-positive, alpha-beta memory T cell - central CD8-positive, alpha-beta memory T lymphocyte - central CD8-positive, alpha-beta memory T-cell - central CD8-positive, alpha-beta memory T-lymphocyte - central memory CD8-positive, alpha-beta T lymphocyte - central memory CD8-positive, alpha-beta T-cell - central memory CD8-positive, alpha-beta T-lymphocyte - cell - This cell type is compatible with the HIPC Lyoplate markers for 'central memory CD8+ T cell', but includes additional markers known to be expressed on central memory CD8+ T cells. - central memory CD8-positive, alpha-beta T cell - - - - - CD8-positive, alpha-beta memory T cell with the phenotype CCR7-positive, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative. - GOC:add - GOC:pam - GOC:tfm - GO_REF:0000031 - PMID:20146720 - PMID:22343568 - - - - - central memory CD8+ T cell - PMID:22343568 - + @@ -17609,23 +7286,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD8-positive, alpha-beta T cell with the phenotype CD69-positive, CD62L-negative, CD127-negative, and CD25-positive, that secretes cytokines. - CD8-positive, alpha-beta cytokine secreting effector T lymphocyte - CD8-positive, alpha-beta cytokine secreting effector T-cell - CD8-positive, alpha-beta cytokine secreting effector T-lymphocyte - cell - CD8-positive, alpha-beta cytokine secreting effector T cell - - - - - A CD8-positive, alpha-beta T cell with the phenotype CD69-positive, CD62L-negative, CD127-negative, and CD25-positive, that secretes cytokines. - GOC:add - GOC:pam - GOC:tfm - GO_REF:0000031 - PMID:20146720 - + @@ -17634,22 +7295,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD8-positive, alpha-beta T cell with memory phenotype indicated by being CD45RO and CD127-positive. This cell type is also described as being CD25-negative, CD44-high, and CD122-high. - CD8-positive, alpha-beta memory T lymphocyte - CD8-positive, alpha-beta memory T-cell - CD8-positive, alpha-beta memory T-lymphocyte - T.8Mem.Sp - cell - CD8-positive, alpha-beta memory T cell - - - - A CD8-positive, alpha-beta T cell with memory phenotype indicated by being CD45RO and CD127-positive. This cell type is also described as being CD25-negative, CD44-high, and CD122-high. - GOC:tfm - GO_REF:0000031 - PMID:20146720 - @@ -17657,26 +7303,7 @@ radial glial cells acting as neural progenitors throughout life. - A mature T cell that differentiated and acquired cytotoxic function with the phenotype perforin-positive and granzyme-B positive. - BTO:0000289 - CALOHA:TS-0190 - FMA:70573 - cytotoxic T lymphocyte - cytotoxic T-cell - cytotoxic T-lymphocyte - cell - cytotoxic T cell - - - - - A mature T cell that differentiated and acquired cytotoxic function with the phenotype perforin-positive and granzyme-B positive. - GOC:add - GOC:pam - GOC:tfm - GO_REF:0000031 - PMID:18395547 - + @@ -17684,22 +7311,7 @@ radial glial cells acting as neural progenitors throughout life. - A differentiated T cell with ability to traffic to peripheral tissues and is capable of mounting a specific immune response. - effector T lymphocyte - effector T-cell - effector T-lymphocyte - cell - effector T cell - - - - A differentiated T cell with ability to traffic to peripheral tissues and is capable of mounting a specific immune response. - GOC:PAM-ADD - GOC:tfm - ISBN:0877799148 - PMID:18395547 - @@ -17707,25 +7319,7 @@ radial glial cells acting as neural progenitors throughout life. - A effector T cell that provides help in the form of secreted cytokines to other immune cells. - BTO:0002417 - T-helper cell - helper T lymphocyte - helper T-cell - helper T-lymphocyte - cell - helper T cell - - - - - A effector T cell that provides help in the form of secreted cytokines to other immune cells. - GOC:add - GOC:pam - GOC:tfm - GO_REF:0000031 - PMID:18395547 - + @@ -17733,35 +7327,7 @@ radial glial cells acting as neural progenitors throughout life. - CD8-positive, alpha-beta memory T cell with the phenotype CCR7-negative, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative. - effector memory CD8+ T cell - effector CD8-positive, alpha-beta memory T cell - effector CD8-positive, alpha-beta memory T lymphocyte - effector CD8-positive, alpha-beta memory T-cell - effector CD8-positive, alpha-beta memory T-lymphocyte - effector memory CD8-positive, alpha-beta T lymphocyte - effector memory CD8-positive, alpha-beta T-cell - effector memory CD8-positive, alpha-beta T-lymphocyte - cell - This cell type is compatible with the HIPC Lyoplate markers for 'effector memory CD8+ T cell', but includes additional markers known to be expressed on effector memory CD8+ T cells. - effector memory CD8-positive, alpha-beta T cell - - - - - CD8-positive, alpha-beta memory T cell with the phenotype CCR7-negative, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative. - GOC:add - GOC:pam - GO_REF:0000031 - PMID:20146720 - PMID:22343568 - - - - - effector memory CD8+ T cell - PMID:22343568 - + @@ -17769,25 +7335,7 @@ radial glial cells acting as neural progenitors throughout life. - An immature alpha-beta T-cell that express Egr2. These cells give rise to T cells expressing NK markers. - immature NK T lymphocyte - immature NK T-cell - immature NK T-lymphocyte - immature NKT cell - cell - immature NK T cell - - - - - An immature alpha-beta T-cell that express Egr2. These cells give rise to T cells expressing NK markers. - GOC:add - GOC:pam - GOC:tfm - GO_REF:0000031 - PMID:17589542 - PMID:19169262 - + @@ -17795,22 +7343,7 @@ radial glial cells acting as neural progenitors throughout life. - An alpha-beta intraepithelial T cell with the phenotype CD8-alpha-alpha-positive located in the columnar epithelium of the gastrointestinal tract. These cells have a memory phenotype of CD2-negative and CD5-negative. - CD8-alpha-alpha-positive, alpha-beta intraepithelial T lymphocyte - CD8-alpha-alpha-positive, alpha-beta intraepithelial T-cell - CD8-alpha-alpha-positive, alpha-beta intraepithelial T-lymphocyte - cell - CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell - - - - An alpha-beta intraepithelial T cell with the phenotype CD8-alpha-alpha-positive located in the columnar epithelium of the gastrointestinal tract. These cells have a memory phenotype of CD2-negative and CD5-negative. - GOC:add - GOC:pam - GO_REF:0000031 - PMID:11685222 - @@ -17818,25 +7351,7 @@ radial glial cells acting as neural progenitors throughout life. - A mature gamma-delta T cell located in the epidermis that regulates wound healing. - DETC - dendritic epidermal T lymphocyte - dendritic epidermal T-cell - dendritic epidermal T-lymphocyte - cell - In mice, DETC have an invariant T cell receptor. - dendritic epidermal T cell - - - - - A mature gamma-delta T cell located in the epidermis that regulates wound healing. - GOC:add - GOC:pam - GOC:tfm - GO_REF:0000031 - PMID:11976459 - + @@ -17844,36 +7359,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD8-positive, alpha-beta positive T cell that has the phenotype T-bet-positive, eomesodermin-positive, CXCR3-positive, CCR6-negative, and is capable of producing interferon-gamma. - BTO:0004793 - BTO:0004888 - FMA:84793 - T-cytotoxic T cell type 1 - Tc1 CD8+ T cell - Tc1 T cell - Tc1 T lymphocyte - Tc1 T-cell - Tc1 T-lymphocyte - cell - This cell type is compatible with the HIPC Lyoplate markers for 'Tc1 CD8+ T cell', but its logical definition includes additional known characteristics of Tc1 T cells. - Tc1 cell - - - - - A CD8-positive, alpha-beta positive T cell that has the phenotype T-bet-positive, eomesodermin-positive, CXCR3-positive, CCR6-negative, and is capable of producing interferon-gamma. - GOC:add - GOC:pam - GO_REF:0000031 - PMID:22343568 - PMID:9914231 - - - - - Tc1 CD8+ T cell - PMID:22343568 - + @@ -17882,28 +7368,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD8-positive, alpha-beta positive T cell expressing GATA-3 and secreting IL-4. - BTO:0004794 - FMA:84794 - T-cytotoxic T cell type 2 - Tc2 T cell - Tc2 T lymphocyte - Tc2 T-cell - Tc2 T-lymphocyte - cell - This cell type is compatible with the HIPC Lyoplate markers for 'non-Tc1/Tc17 CD8+ T cell' (see CL:0001052), but includes the additional necessary and sufficient conditions to allow classification as a Tc2 T cell. - Tc2 cell - - - - - A CD8-positive, alpha-beta positive T cell expressing GATA-3 and secreting IL-4. - GOC:add - GOC:pam - GOC:tfm - GO_REF:0000031 - PMID:9914231 - + @@ -17911,30 +7376,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD8-positive alpha beta-positive T cell with the phenotype FoxP3-positive and having suppressor function. - CD8+CD25+ T cell - CD8+CD25+ T lymphocyte - CD8+CD25+ T(reg) - CD8+CD25+ T-cell - CD8+CD25+ T-lymphocyte - CD8+CD25+ Treg - CD8-positive, CD25-positive Treg - CD8-positive, CD25-positive, alpha-beta regulatory T lymphocyte - CD8-positive, CD25-positive, alpha-beta regulatory T-cell - CD8-positive, CD25-positive, alpha-beta regulatory T-lymphocyte - cell - CD8-positive, CD25-positive, alpha-beta regulatory T cell - - - - - A CD8-positive alpha beta-positive T cell with the phenotype FoxP3-positive and having suppressor function. - GOC:add - GOC:pam - GOC:tfm - GO_REF:0000031 - PMID:19118505 - + @@ -17942,31 +7384,7 @@ radial glial cells acting as neural progenitors throughout life. - CD8-positive, alpha-beta positive regulatory T cell with the phenotype CD28-negative and FoxP3-positive. - CD8+CD28- T cell - CD8+CD28- T lymphocyte - CD8+CD28- T(reg) - CD8+CD28- T-cell - CD8+CD28- T-lymphocyte - CD8+CD28- Treg - CD8-positive, CD28-negative T(reg) - CD8-positive, CD28-negative Treg - CD8-positive, CD28-negative, alpha-beta regulatory T lymphocyte - CD8-positive, CD28-negative, alpha-beta regulatory T-cell - CD8-positive, CD28-negative, alpha-beta regulatory T-lymphocyte - cell - CD8-positive, CD28-negative, alpha-beta regulatory T cell - - - - - CD8-positive, alpha-beta positive regulatory T cell with the phenotype CD28-negative and FoxP3-positive. - GOC:add - GOC:pam - GOC:tfm - GO_REF:0000031 - PMID:19118505 - + @@ -17974,27 +7392,7 @@ radial glial cells acting as neural progenitors throughout life. - An alpha-beta T cell expressing NK cell markers that is CD1d restricted and expresses specific V-alpha chains. NK T cells of this type recognize the glycolipid alpha-galactosylceramide in the context of CD1d. - classical NK T cell - type I NK T lymphocyte - type I NK T-cell - type I NK T-lymphocyte - type I NKT cell - cell - invariant NK T cell - In mouse the canonical TCR is V-alpha-14, and in humans it is V-alpha 24. - type I NK T cell - - - - - An alpha-beta T cell expressing NK cell markers that is CD1d restricted and expresses specific V-alpha chains. NK T cells of this type recognize the glycolipid alpha-galactosylceramide in the context of CD1d. - GOC:add - GOC:pam - GOC:tfm - GO_REF:0000031 - PMID:15039760 - + @@ -18002,24 +7400,7 @@ radial glial cells acting as neural progenitors throughout life. - An alpha-beta T cell expressing NK call markers that is CD1d restricted and expresses a diverse TCR repertoire. Type II NKT cells do not become activated by alpha-galactosylceramide when presented by CD1d. - type II NK T lymphocyte - type II NK T-cell - type II NK T-lymphocyte - type II NKT cell - cell - type II NK T cell - - - - - An alpha-beta T cell expressing NK call markers that is CD1d restricted and expresses a diverse TCR repertoire. Type II NKT cells do not become activated by alpha-galactosylceramide when presented by CD1d. - GOC:add - GOC:pam - GOC:tfm - GO_REF:0000031 - PMID:15039760 - + @@ -18027,25 +7408,7 @@ radial glial cells acting as neural progenitors throughout life. - A type I NK T cell that has the phenotype CD4-positive. - CD4-positive type I NK T lymphocyte - CD4-positive type I NK T-cell - CD4-positive type I NK T-lymphocyte - CD4-positive type I NKT cell - NKT.4+.SP - cell - CD4-positive type I NK T cell - - - - - A type I NK T cell that has the phenotype CD4-positive. - GOC:add - GOC:pam - GOC:tfm - GO_REF:0000031 - PMID:17303398 - + @@ -18053,25 +7416,7 @@ radial glial cells acting as neural progenitors throughout life. - A type I NK T cell that has the phenotype CD4-negative and CD8-negative. - CD4-negative, CD8-negative type I NK T lymphocyte - CD4-negative, CD8-negative type I NK T-cell - CD4-negative, CD8-negative type I NK T-lymphocyte - CD4-negative, CD8-negative type I NKT cell - NKT.4-.Sp - cell - CD4-negative, CD8-negative type I NK T cell - - - - - A type I NK T cell that has the phenotype CD4-negative and CD8-negative. - GOC:add - GOC:pam - GOC:tfm - GO_REF:0000031 - PMID:18997862 - + @@ -18080,24 +7425,7 @@ radial glial cells acting as neural progenitors throughout life. - A type I NK T cell that has been recently activated, secretes interferon-gamma and IL-4, and has the phenotype CD4-positive, CD69-positive, and downregulated NK markers. - activated CD4-positive type I NK T lymphocyte - activated CD4-positive type I NK T-cell - activated CD4-positive type I NK T-lymphocyte - activated CD4-positive type I NKT cell - cell - activated CD4-positive type I NK T cell - - - - - A type I NK T cell that has been recently activated, secretes interferon-gamma and IL-4, and has the phenotype CD4-positive, CD69-positive, and downregulated NK markers. - GOC:add - GOC:pam - GOC:tfm - GO_REF:0000031 - PMID:17303398 - + @@ -18106,25 +7434,7 @@ radial glial cells acting as neural progenitors throughout life. - A mature NK T cell that secretes interferon-gamma and enhances type 1 immune responses. - CD4-positive type I NK T cell secreting IFN-gamma - CD4-positive type I NK T lymphocyte secreting interferon-gamma - CD4-positive type I NK T-cell secreting interferon-gamma - CD4-positive type I NK T-lymphocyte secreting interferon-gamma - CD4-positive type I NKT cell secreting interferon-gamma - cell - CD4-positive type I NK T cell secreting interferon-gamma - - - - - A mature NK T cell that secretes interferon-gamma and enhances type 1 immune responses. - GOC:add - GOC:pam - GOC:tfm - GO_REF:0000031 - PMID:17303398 - + @@ -18133,24 +7443,7 @@ radial glial cells acting as neural progenitors throughout life. - A mature NK T cell that predominantly secretes type 2 cytokines such as interleukin-4 and interleukin-13 and enhances type 2 immune responses. - CD4-positive type I NK T cell secreting IL-4 - CD4-positive type I NK T lymphocyte secreting interleukin-4 - CD4-positive type I NK T-cell secreting interleukin-4 - CD4-positive type I NK T-lymphocyte secreting interleukin-4 - CD4-positive type I NKT cell secreting interleukin-4 - cell - CD4-positive type I NK T cell secreting interleukin-4 - - - - - A mature NK T cell that predominantly secretes type 2 cytokines such as interleukin-4 and interleukin-13 and enhances type 2 immune responses. - GOC:add - GOC:pam - GOC:tfm - GO_REF:0000031 - + @@ -18159,24 +7452,7 @@ radial glial cells acting as neural progenitors throughout life. - A type I NK T cell that has been recently activated, secretes interferon-gamma and interleukin-4, and has phenotype CD4-negative, CD8-negative, CD69-positive, and downregulated NK markers. - activated CD4-negative, CD8-negative type I NK T lymphocyte - activated CD4-negative, CD8-negative type I NK T-cell - activated CD4-negative, CD8-negative type I NK T-lymphocyte - activated CD4-negative, CD8-negative type I NKT cell - cell - activated CD4-negative, CD8-negative type I NK T cell - - - - - A type I NK T cell that has been recently activated, secretes interferon-gamma and interleukin-4, and has phenotype CD4-negative, CD8-negative, CD69-positive, and downregulated NK markers. - GOC:add - GOC:pam - GOC:tfm - GO_REF:0000031 - PMID:17303398 - + @@ -18185,25 +7461,7 @@ radial glial cells acting as neural progenitors throughout life. - A mature NK T cell that secretes interferon-gamma and enhances Th1 immune responses. - CD4-negative, CD8-negative type I NK T cell secreting IFN-gamma - CD4-negative, CD8-negative type I NK T lymphocyte secreting interferon-gamma - CD4-negative, CD8-negative type I NK T-cell secreting interferon-gamma - CD4-negative, CD8-negative type I NK T-lymphocyte secreting interferon-gamma - CD4-negative, CD8-negative type I NKT cell secreting interferon-gamma - cell - CD4-negative, CD8-negative type I NK T cell secreting interferon-gamma - - - - - A mature NK T cell that secretes interferon-gamma and enhances Th1 immune responses. - GOC:add - GOC:pam - GOC:tfm - GO_REF:0000031 - PMID:17303398 - + @@ -18212,25 +7470,7 @@ radial glial cells acting as neural progenitors throughout life. - A mature NK T cell that secretes interleukin-4 and enhances Th2 immune responses. - CD4-negative, CD8-negative type I NK T cell secreting IL-4 - CD4-negative, CD8-negative type I NK T lymphocyte secreting interleukin-4 - CD4-negative, CD8-negative type I NK T-cell secreting interleukin-4 - CD4-negative, CD8-negative type I NK T-lymphocyte secreting interleukin-4 - CD4-negative, CD8-negative type I NKT cell secreting interleukin-4 - cell - CD4-negative, CD8-negative type I NK T cell secreting interleukin-4 - - - - - A mature NK T cell that secretes interleukin-4 and enhances Th2 immune responses. - GOC:add - GOC:pam - GOC:tfm - GO_REF:0000031 - PMID:17303398 - + @@ -18239,24 +7479,7 @@ radial glial cells acting as neural progenitors throughout life. - A type II NK T cell that has been recently activated, secretes interferon-gamma and interleukin-4, and has the phenotype CD69-positive and downregulated NK markers. - activated type II NK T lymphocyte - activated type II NK T-cell - activated type II NK T-lymphocyte - activated type II NKT cell - cell - activated type II NK T cell - - - - - A type II NK T cell that has been recently activated, secretes interferon-gamma and interleukin-4, and has the phenotype CD69-positive and downregulated NK markers. - GOC:add - GOC:pam - GOC:tfm - GO_REF:0000031 - PMID:17964217 - + @@ -18265,24 +7488,7 @@ radial glial cells acting as neural progenitors throughout life. - A type II NK T cell that has been recently activated, secretes interferon-gamma, and has the phenotype CD69-positive and downregulated NK markers. - type II NK T cell secreting IFN-gamma - type II NK T lymphocyte secreting interferon-gamma - type II NK T-cell secreting interferon-gamma - type II NK T-lymphocyte secreting interferon-gamma - type II NKT cell secreting interferon-gamma - cell - type II NK T cell secreting interferon-gamma - - - - - A type II NK T cell that has been recently activated, secretes interferon-gamma, and has the phenotype CD69-positive and downregulated NK markers. - GOC:add - GOC:pam - GO_REF:0000031 - PMID:17964217 - + @@ -18291,25 +7497,7 @@ radial glial cells acting as neural progenitors throughout life. - A type II NK T cell that has been recently activated, secretes interleukin-4, and has the phenotype CD69-positive and downregulated NK markers. - type II NK T cell secreting IL-4 - type II NK T lymphocyte secreting interleukin-4 - type II NK T-cell secreting interleukin-4 - type II NK T-lymphocyte secreting interleukin-4 - type II NKT cell secreting interleukin-4 - cell - type II NK T cell secreting interleukin-4 - - - - - A type II NK T cell that has been recently activated, secretes interleukin-4, and has the phenotype CD69-positive and downregulated NK markers. - GOC:add - GOC:pam - GOC:tfm - GO_REF:0000031 - PMID:17964217 - + @@ -18318,23 +7506,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD4-positive, alpha-beta T cell that has cytotoxic function. - CD4-positive, alpha-beta cytotoxic T lymphocyte - CD4-positive, alpha-beta cytotoxic T-cell - CD4-positive, alpha-beta cytotoxic T-lymphocyte - cell - CD4-positive, alpha-beta cytotoxic T cell - - - - - A CD4-positive, alpha-beta T cell that has cytotoxic function. - GOC:add - GOC:pam - GOC:tfm - GO_REF:0000031 - PMID:18440213 - + @@ -18342,22 +7514,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD4-negative, CD8-negative, alpha-beta intraepithelial T cell that is found in the columnar epithelium of the gastrointestinal tract. - CD4-negative, CD8-negative, alpha-beta intraepithelial T lymphocyte - CD4-negative, CD8-negative, alpha-beta intraepithelial T-cell - CD4-negative, CD8-negative, alpha-beta intraepithelial T-lymphocyte - cell - CD4-negative, CD8-negative, alpha-beta intraepithelial T cell - - - - A CD4-negative, CD8-negative, alpha-beta intraepithelial T cell that is found in the columnar epithelium of the gastrointestinal tract. - GOC:add - GOC:pam - GO_REF:0000031 - PMID:11685222 - @@ -18366,32 +7523,7 @@ radial glial cells acting as neural progenitors throughout life. - A lymphoid progenitor cell that is found in bone marrow, gives rise to B cells, T cells, natural killer cells and dendritic cells, and has the phenotype Lin-negative, Kit-positive, Sca-1-positive, FLT3-positive, CD34-positive, CD150 negative, and GlyA-negative. - ELP - LMPP - lymphoid-primed multipotent progenitor - cell - GMLP - Markers are associated with mouse cells. ELP transcription factors include E2A-positive, Ikaros-positive, EBF-negative, Pax5-negative, PU.1-negative. - early lymphoid progenitor - - - - - A lymphoid progenitor cell that is found in bone marrow, gives rise to B cells, T cells, natural killer cells and dendritic cells, and has the phenotype Lin-negative, Kit-positive, Sca-1-positive, FLT3-positive, CD34-positive, CD150 negative, and GlyA-negative. - GOC:add - GOC:dsd - GOC:pam - GOC:tfm - GO_REF:0000031 - PMID:19022770 - - - - - GMLP - PMID:18371378 - + @@ -18399,24 +7531,9 @@ radial glial cells acting as neural progenitors throughout life. - Cell committed to natural killer cell lineage that has the phenotype CD122-positive, CD34-positive, and CD117-positive. This cell type lacks expression of natural killer receptor proteins. - pre-NK cell - cell - These cells are also reportedly CD7-low, CD10-negative, CD45RA-positive, alpha-4-beta-7 integrin-high. - pre-natural killer cell - - - - - Cell committed to natural killer cell lineage that has the phenotype CD122-positive, CD34-positive, and CD117-positive. This cell type lacks expression of natural killer receptor proteins. - GOC:add - GOC:dsd - GOC:pam - GOC:tfm - GO_REF:0000031 - PMID:16551251 - PMID:17100874 - + + + @@ -18424,32 +7541,8 @@ radial glial cells acting as neural progenitors throughout life. - NK cell that has the phenotype CD56-bright, CD16-negative, and CD84-positive with the function to secrete interferon-gamma but is not cytotoxic. - CD16-CD56bright NK cell - CD16-negative, CD56-bright NK cell - CD56-bright cytokine secreting NK cell - CD56-bright cytokine secreting natural killer cell - cell - This cell type is compatible with the HIPC Lyoplate markers for 'CD16-CD56bright NK cell'. Markers are associated with human cell types. - CD16-negative, CD56-bright natural killer cell - - - - - NK cell that has the phenotype CD56-bright, CD16-negative, and CD84-positive with the function to secrete interferon-gamma but is not cytotoxic. - GOC:add - GOC:pam - GOC:tfm - GO_REF:0000031 - PMID:19796267 - PMID:22343568 - - - - - CD16-CD56bright NK cell - PMID:22343568 - + + @@ -18457,35 +7550,7 @@ radial glial cells acting as neural progenitors throughout life. - A mature natural killer cell that has the phenotype CD56-low, CD16-positive and which is capable of cytotoxicity and cytokine production. - CD16+CD56+ NK cell - CD16-positive, CD56-dim NK cell - CD16-positive, CD56-low NK cell - CD16-positive, CD56-low natural killer cell - CD16-positive, CD56-positive NK cell - CD16-positive, CD56-positive natural killer cell - cytotoxic CD56-dim NK cell - cytotoxic CD56-dim natural killer cell - cell - This cell type is compatible with the HIPC Lyoplate markers for 'CD16+CD56+ NK cell'. Markers are associated with human cell types. - CD16-positive, CD56-dim natural killer cell - - - - - A mature natural killer cell that has the phenotype CD56-low, CD16-positive and which is capable of cytotoxicity and cytokine production. - GOC:add - GOC:pam - GO_REF:0000031 - PMID:19796267 - PMID:22343568 - - - - - CD16+CD56+ NK cell - PMID:22343568 - + @@ -18494,23 +7559,7 @@ radial glial cells acting as neural progenitors throughout life. - An alpha-beta T cell that is found in the lamina propria of mucosal tissues and is restricted by the MR-1 molecule. - mucosal invariant T lymphocyte - mucosal invariant T-cell - mucosal invariant T-lymphocyte - cell - mucosal invariant T cell - - - - - An alpha-beta T cell that is found in the lamina propria of mucosal tissues and is restricted by the MR-1 molecule. - GOC:add - GOC:pam - GOC:tfm - GO_REF:0000031 - PMID:19416870 - + @@ -18518,20 +7567,7 @@ radial glial cells acting as neural progenitors throughout life. - A dendritic cell arising in thymus that has the phenotype CD11c-positive, CD11b-negative, and CD45RA-negative. - cell - In the mouse this cell expresses CD8-alpha-alpha. - thymic conventional dendritic cell - - - - A dendritic cell arising in thymus that has the phenotype CD11c-positive, CD11b-negative, and CD45RA-negative. - GOC:add - GOC:pam - GO_REF:0000031 - PMID:19273629 - @@ -18539,20 +7575,7 @@ radial glial cells acting as neural progenitors throughout life. - A plasmacytoid dendritic cell developing in the thymus with phenotype CD11c-negative or low, CD45RA-positive, CD11b-negative, and CD123-positive. - cell - thymic plasmacytoid dendritic cell - - - - A plasmacytoid dendritic cell developing in the thymus with phenotype CD11c-negative or low, CD45RA-positive, CD11b-negative, and CD123-positive. - GOC:add - GOC:pam - GOC:tfm - GO_REF:0000031 - PMID:19941119 - @@ -18560,31 +7583,7 @@ radial glial cells acting as neural progenitors throughout life. - A Be cell that facilitates development of T-helper 1 (Th1) phenotype in CD4-positive T cells, and secretes high levels of interleukin-2, tumor necrosis factor-alpha and interferon-gamma. - B effector 1 cell - cell - B effector cell type 1 - Be1 cells are also reportedly capable of secreting IL-6, IL-10, and IL-12. They are also reportedly CD11b-negative and B220-positive. - Be1 Cell - - - - - A Be cell that facilitates development of T-helper 1 (Th1) phenotype in CD4-positive T cells, and secretes high levels of interleukin-2, tumor necrosis factor-alpha and interferon-gamma. - GOC:dsd - GOC:msz - GOC:tfm - GO_REF:0000031 - PMID:11101868 - PMID:20224569 - - - - - B effector 1 cell - PMID:11101868 - PMID:20224569 - + @@ -18592,31 +7591,7 @@ radial glial cells acting as neural progenitors throughout life. - A Be cell that facilitates development of T-helper 2 (Th2) phenotype T cells, and secretes high levels of interleukin-2, interleukin-10, interleukin-4, and interleukin-6. - B effector 2 cell - cell - B effector cell type 2 - Be2 cells are also reportedly capable of secreting IL-13 and TNF. They are also reportedly CD11b-negative and B220-positive. - Be2 cell - - - - - A Be cell that facilitates development of T-helper 2 (Th2) phenotype T cells, and secretes high levels of interleukin-2, interleukin-10, interleukin-4, and interleukin-6. - GOC:dsd - GOC:msz - GOC:tfm - GO_REF:0000031 - PMID:11101868 - PMID:20224569 - - - - - B effector 2 cell - PMID:11101868 - PMID:20224569 - + @@ -18624,21 +7599,7 @@ radial glial cells acting as neural progenitors throughout life. - A lymphocyte of B lineage is a lymphocyte that expresses CD19 on the cell surface. An additional defining characteristic is the commitment to express an immunoglobulin complex. - cell - Types of B lineage lymphocytes include B cells and antibody secreting cells (plasmablasts and plasma cells). Lymphocytes of B cell lineage can be distinguished from those of T cell lineage by their lack of CD3e (as part of the T cell receptor complex). - lymphocyte of B lineage - - - - A lymphocyte of B lineage is a lymphocyte that expresses CD19 on the cell surface. An additional defining characteristic is the commitment to express an immunoglobulin complex. - GOC:add - GOC:rhs - GOC:tfm - GO_REF:0000031 - ISBN:0781735149 - @@ -18646,20 +7607,7 @@ radial glial cells acting as neural progenitors throughout life. - A lymphocyte of B lineage that is devoted to secreting large amounts of immunoglobulin. - cell - antibody secreting cell - - - - A lymphocyte of B lineage that is devoted to secreting large amounts of immunoglobulin. - GOC:add - GOC:tfm - GO_REF:0000031 - ISBN:0721601464 - ISBN:0781735149 - @@ -18667,18 +7615,7 @@ radial glial cells acting as neural progenitors throughout life. - A long lived plasma cell that secretes IgE. - cell - IgE plasma cell - - - - A long lived plasma cell that secretes IgE. - GOC:msz - GO_REF:0000031 - ISBN:781735149 - @@ -18686,25 +7623,7 @@ radial glial cells acting as neural progenitors throughout life. - A class switched memory B cell that expresses IgE on the cell surface. - IgE memory B lymphocyte - IgE memory B-cell - IgE memory B-lymphocyte - memory IgE B cell - memory IgE B lymphocyte - memory IgE B-cell - memory IgE B-lymphocyte - cell - IgE memory B cell - - - - - A class switched memory B cell that expresses IgE on the cell surface. - GOC:rhs - GO_REF:0000031 - ISBN:0781765196 - + @@ -18712,17 +7631,7 @@ radial glial cells acting as neural progenitors throughout life. - A plasmablast that secretes IgD, and which occur in a small proportion of B cells in the adult. - cell - IgD plasmablast - - - - A plasmablast that secretes IgD, and which occur in a small proportion of B cells in the adult. - GOC:msz - GO_REF:0000031 - @@ -18730,17 +7639,7 @@ radial glial cells acting as neural progenitors throughout life. - A plasmablast that secretes IgE. - cell - IgE plasmablast - - - - A plasmablast that secretes IgE. - GOC:msz - GO_REF:0000031 - @@ -18748,18 +7647,7 @@ radial glial cells acting as neural progenitors throughout life. - A short lived plasma cell that secretes IgE. - cell - IgE short lived plasma cell - - - - A short lived plasma cell that secretes IgE. - GOC:msz - GO_REF:0000031 - ISBN:781735149 - @@ -18767,19 +7655,7 @@ radial glial cells acting as neural progenitors throughout life. - An preBRC-positive large pre-B-II cell is a large pre-B-II cell that is pre-B cell receptor-positive, composed of surrogate light chain protein (SL), which is composed of VpreB , Lambda 5/14.1, in complex with immunoglobulin mu heavy chain (IgHmu) on the cell surface. - cell - preBCR-positive large pre-B-II cell - - - - An preBRC-positive large pre-B-II cell is a large pre-B-II cell that is pre-B cell receptor-positive, composed of surrogate light chain protein (SL), which is composed of VpreB , Lambda 5/14.1, in complex with immunoglobulin mu heavy chain (IgHmu) on the cell surface. - GOC:rhs - GOC:tfm - GO_REF:0000031 - PMID:9785673 - @@ -18787,19 +7663,7 @@ radial glial cells acting as neural progenitors throughout life. - A pre-BCR-negative large pre-B-II cell is a large pre-B-II cell that is pre-B cell receptor-negative, composed of surrogate light chain protein (SL), which is composed of VpreB and Lambda 5/14.1, in complex with immunoglobulin mu heavy chain (IgHmu), on the cell surface, and lack a DNA rearrangement of immunoglobulin light chain genes. - cell - preBCR-negative large pre-B-II cell - - - - A pre-BCR-negative large pre-B-II cell is a large pre-B-II cell that is pre-B cell receptor-negative, composed of surrogate light chain protein (SL), which is composed of VpreB and Lambda 5/14.1, in complex with immunoglobulin mu heavy chain (IgHmu), on the cell surface, and lack a DNA rearrangement of immunoglobulin light chain genes. - GOC:rhs - GOC:tfm - GO_REF:0000031 - PMID:9785673 - @@ -18807,24 +7671,7 @@ radial glial cells acting as neural progenitors throughout life. - A small pre-B-II cell is a pre-B-II cell that is Rag1-positive, Rag2-positive, pre-BCR-negative, and BCR-negative, is not proliferating, and carries a DNA rearrangement of one or more immunoglobulin light chain genes. - small pre-BII cell - cell - Small pre-B-II cells are also reportedly CD10-positive, CD19-positive, CD34-negative, CD79a-positive, CD127-negative, TdT-negative, Vpre-B-negative, sIgM-negative, and sIgD-negative. Transcription factors: PU.1-positive, Ikaros-positive, E2A-positive, and PAX5-positive. - small pre-B-II cell - - - - - A small pre-B-II cell is a pre-B-II cell that is Rag1-positive, Rag2-positive, pre-BCR-negative, and BCR-negative, is not proliferating, and carries a DNA rearrangement of one or more immunoglobulin light chain genes. - GOC:dsd - GOC:rhs - GOC:tfm - GO_REF:0000031 - PMID:16551251 - PMID:18432934 - PMID:9785673 - + @@ -18832,25 +7679,8 @@ radial glial cells acting as neural progenitors throughout life. - A pre-B-II cell is a precursor B cell that expresses immunoglobulin mu heavy chain (IgHmu+), and lack expression of CD34, TdT, immunoglobulin kappa light chain and immunoglobulin lambda light chain. - BTO:0001133 - CALOHA:TS-0819 - pre-B-lymphocyte - pre-BII cell - cell - pre-B-II cell are also reportedly CD19-positive, CD22-positive, CD38-positive, CD45-positive, and CD48-positive. - pre-B-II cell - - - - - A pre-B-II cell is a precursor B cell that expresses immunoglobulin mu heavy chain (IgHmu+), and lack expression of CD34, TdT, immunoglobulin kappa light chain and immunoglobulin lambda light chain. - GOC:dsd - GOC:rhs - GOC:tfm - GO_REF:0000031 - PMID:9785673 - + + @@ -18858,32 +7688,7 @@ radial glial cells acting as neural progenitors throughout life. - A pre-B-I cell is a precursor B cell that expresses CD34 and surrogate immunoglobulin light chain (VpreB , Lambda 5 (mouse)/14.1 (human)) on the cell surface, and TdT, Rag1,and Rag2 intracellularly. Cell type carries a D-JH DNA rearrangement, and lacks expression of immunglobulin heavy chain protein. - pre-BI cell - cell - pro-B cell (Philadelphia nomenclature) - Human pre-B-I cells are reportedly CD10-positive, CD19-positive, CD22-positive, CD38-positive, CD45-low, CD79a-positive, CD127-negative, pre-BCR-negative, IgM-negative, IgD-negative, and Tdt-positive. Transcription factors expressed: Pax5-positive. - pre-B-I cell - - - - - A pre-B-I cell is a precursor B cell that expresses CD34 and surrogate immunoglobulin light chain (VpreB , Lambda 5 (mouse)/14.1 (human)) on the cell surface, and TdT, Rag1,and Rag2 intracellularly. Cell type carries a D-JH DNA rearrangement, and lacks expression of immunglobulin heavy chain protein. - GOC:dsd - GOC:rhs - GOC:tfm - GO_REF:0000031 - PMID:16551251 - PMID:18432934 - PMID:20839338 - PMID:9785673 - - - - - pro-B cell (Philadelphia nomenclature) - PMID:11244048 - + @@ -18891,30 +7696,7 @@ radial glial cells acting as neural progenitors throughout life. - A large pre-B-II cell is a pre-B-II cell that is proliferating and is Rag1-negative and Rag2-negative. - large pre-B cell - large pre-BII cell - cell - Large pre-B-II cells are also reportedly CD10-positive, CD19-positive, CD34-negative, CD79a-positive, CD127-negative, TdT-negative, Vpre-B-positive, pre-BCR-positive, sIgM-negative, and sIgD-negative. Transcription factors: PU.1-positive, Ikaros-positive, E2A-positive, and PAX5-positive. - large pre-B-II cell - - - - - A large pre-B-II cell is a pre-B-II cell that is proliferating and is Rag1-negative and Rag2-negative. - GOC:dsd - GOC:rhs - GO_REF:0000031 - PMID:16551251 - PMID:18432934 - PMID:9785673 - - - - - large pre-B cell - PMID:11244048 - + @@ -18922,26 +7704,7 @@ radial glial cells acting as neural progenitors throughout life. - A transitional stage B cell that migrates from the bone marrow into the peripheral circulation, and finally to the spleen. This cell type has the phenotype surface IgM-positive, surface IgD-negative, CD21-negative, CD23-negative, and CD62L-negative, and CD93-positive. This cell type has also been described as IgM-high, CD19-positive, B220-positive, AA4-positive, and CD23-negative. - T1 B lymphocyte - T1 B-cell - T1 B-lymphocyte - transitional stage 1 B cell - cell - T1 B cells are also reportedly CD10-negative/positive??, CD20-positive, CD24-positive, CD38-positive, CD48-positive, CD84-positive, CD150-positive, CD244-negative, and CD352-positive. - T1 B cell - - - - - A transitional stage B cell that migrates from the bone marrow into the peripheral circulation, and finally to the spleen. This cell type has the phenotype surface IgM-positive, surface IgD-negative, CD21-negative, CD23-negative, and CD62L-negative, and CD93-positive. This cell type has also been described as IgM-high, CD19-positive, B220-positive, AA4-positive, and CD23-negative. - GOC:dsd - GOC:msz - GOC:tfm - GO_REF:0000031 - PMCID:PMC2193793 - PMID:12810111 - + @@ -18949,26 +7712,7 @@ radial glial cells acting as neural progenitors throughout life. - A transitional stage B cell that has the phenotype surface IgM-positive, surface IgD-postive, CD21-positive, CD23-positive, CD62L-negative, CD93-positive and is located in the splenic B follicles. This cell type has also been described as IgM-high, CD19-positive, B220-positive, AA4-positive, and CD23-positive. - T2 B lymphocyte - T2 B-cell - T2 B-lymphocyte - transitional stage 2 B cell - cell - T2 B cells are also reportedly CD20-positive, CD24-positive, CD38-positive, CD48-positive, CD84-positive, CD150-positive, CD244-negative, and CD352-positive. - T2 B cell - - - - - A transitional stage B cell that has the phenotype surface IgM-positive, surface IgD-postive, CD21-positive, CD23-positive, CD62L-negative, CD93-positive and is located in the splenic B follicles. This cell type has also been described as IgM-high, CD19-positive, B220-positive, AA4-positive, and CD23-positive. - GOC:dsd - GOC:msz - GOC:tfm - GO_REF:0000031 - PMCID:PMC2193793 - PMID:12810111 - + @@ -18976,32 +7720,7 @@ radial glial cells acting as neural progenitors throughout life. - A transitional stage B cell that expresses surface IgM and IgD, and CD62L. This cell type appears to be an anergic B cell that does not proliferate upon BCR signaling, is found in the spleen and lymph nodes, and has the phenotype surface IgM-positive, surface IgD-positive, CD21-positive, CD23-positive, CD62L-positive, and CD93-positive. This cell type has also been described as IgM-low, CD19-positive, B220-positive, AA4-positive, and CD23-positive (i.e. this cell-type is distinguished from T2 cells by surface expression of IgM). - An1 B cell - T3 B lymphocyte - T3 B-cell - T3 B-lymphocyte - transitional stage 3 B cell - cell - T3 B cell - - - - - A transitional stage B cell that expresses surface IgM and IgD, and CD62L. This cell type appears to be an anergic B cell that does not proliferate upon BCR signaling, is found in the spleen and lymph nodes, and has the phenotype surface IgM-positive, surface IgD-positive, CD21-positive, CD23-positive, CD62L-positive, and CD93-positive. This cell type has also been described as IgM-low, CD19-positive, B220-positive, AA4-positive, and CD23-positive (i.e. this cell-type is distinguished from T2 cells by surface expression of IgM). - GOC:msz - GOC:tfm - GO_REF:0000031 - PMID:12810111 - PMID:17174121 - http://www.immgen.org/index_content.html - - - - - An1 B cell - PMID:17174121 - + @@ -19010,25 +7729,7 @@ radial glial cells acting as neural progenitors throughout life. - A follicular B cell that is IgD-positive, CD23-negative, and CD38-negative. This naive cell type is activated in the extrafollicular areas through interaction with interdigitating dendritic cells and antigen-specific CD4-positive T cells. - Bm1 B lymphocyte - Bm1 B-cell - Bm1 B-lymphocyte - cell - These cells are also reportedly CD10-negative, CD39-positive, CD44-positive, CD71-negative, CD77-negative, IgM-positive, IgG-negative, IgA-negative, and IgE-negative. - Bm1 B cell - - - - - A follicular B cell that is IgD-positive, CD23-negative, and CD38-negative. This naive cell type is activated in the extrafollicular areas through interaction with interdigitating dendritic cells and antigen-specific CD4-positive T cells. - GOC:dsd - GOC:msz - GO_REF:0000031 - PMID:17992590 - PMID:18432934 - PMID:8006591 - + @@ -19036,25 +7737,7 @@ radial glial cells acting as neural progenitors throughout life. - A follicular B cell that is IgD-positive and CD23-positive and CD38-positive. This naive cell type is activated in the extrafollicular areas via interaction with dendritic cells and antigen specific T cells. - Bm2 B lymphocyte - Bm2 B-cell - Bm2 B-lymphocyte - cell - These cells are also CD10-negative, CD39-positive, CD44-positive, CD71-negative, CD77-negative, IgM-positive, IgG-negative, IgA-negative, and IgE-negative. - Bm2 B cell - - - - - A follicular B cell that is IgD-positive and CD23-positive and CD38-positive. This naive cell type is activated in the extrafollicular areas via interaction with dendritic cells and antigen specific T cells. - GOC:dsd - GOC:msz - GO_REF:0000031 - PMID:17992590 - PMID:18432934 - PMID:8006591 - + @@ -19062,23 +7745,7 @@ radial glial cells acting as neural progenitors throughout life. - A germinal center B cell that develops from a Bm3 B cell. This cell has the phenotype IgM-negative, IgD-positive, and CD38-positive. - Bm3-delta B lymphocyte - Bm3-delta B-cell - Bm3-delta B-lymphocyte - cell - Bm3-delta B cell - - - - - A germinal center B cell that develops from a Bm3 B cell. This cell has the phenotype IgM-negative, IgD-positive, and CD38-positive. - GOC:add - GOC:msz - GOC:tfm - GO_REF:0000031 - PMID:9280752 - + @@ -19086,31 +7753,7 @@ radial glial cells acting as neural progenitors throughout life. - A germinal center B cell that founds a germinal center, and has the phenotype IgD-positive, CD38-positive, and CD23-negative. - Bm2' B lymphocyte - Bm2' B-cell - Bm2' B-lymphocyte - Bm2-prime B cell - Bm2-prime B lymphocyte - Bm2-prime B-cell - Bm2-prime B-lymphocyte - cell - germinal center founder cell - Bm2' B cells are also reportedly CD10-positive, CD39-negative, CD44-negative, CD71-positive, CD77-negative, IgM-positive, IgG-negative, IgA-negative, and IgE-negative. - Bm2' B cell - - - - - A germinal center B cell that founds a germinal center, and has the phenotype IgD-positive, CD38-positive, and CD23-negative. - GOC:dsd - GOC:msz - GOC:tfm - GO_REF:0000031 - PMID:17992590 - PMID:18432934 - PMID:8006591 - + @@ -19118,31 +7761,7 @@ radial glial cells acting as neural progenitors throughout life. - A germinal center B cell that is rapidly dividing and has the phenotype IgD-negative, CD38-positive, and CD77-positive. Somatic hypermutation of the immunoglobulin V gene region can occur during proliferation of this cell type. - Bm3 B lymphocyte - Bm3 B-cell - Bm3 B-lymphocyte - cell - centroblast - Bm3 B cells are also reportedly CD10-positive, CD23-negative, CD39-negative, CD44-negative, CD71-positive, and CD77-positive. - Bm3 B cell - - - - - A germinal center B cell that is rapidly dividing and has the phenotype IgD-negative, CD38-positive, and CD77-positive. Somatic hypermutation of the immunoglobulin V gene region can occur during proliferation of this cell type. - GOC:dsd - GOC:msz - GO_REF:0000031 - PMID:18432934 - PMID:8006591 - - - - - centroblast - PMID:8006591 - + @@ -19150,31 +7769,7 @@ radial glial cells acting as neural progenitors throughout life. - A germinal center B cell that has the phenotype CD77-negative, IgD-negative, and CD38-positive. These cells have undergone somatic mutation of the B cell receptor. - Bm4 B lymphocyte - Bm4 B-cell - Bm4 B-lymphocyte - cell - centrocyte - Bm4 B cells are also reportedly CD10-positive, CD23-negative, CD39-negative, CD44-positive, and CD71-positive. - Bm4 B cell - - - - - A germinal center B cell that has the phenotype CD77-negative, IgD-negative, and CD38-positive. These cells have undergone somatic mutation of the B cell receptor. - GOC:dsd - GOC:msz - GO_REF:0000031 - PMID:18432934 - PMID:8006591 - - - - - centrocyte - PMID:17992590 - + @@ -19182,25 +7777,7 @@ radial glial cells acting as neural progenitors throughout life. - A memory B cell arising in the germinal center that is IgD-negative and has undergone somatic mutation of the variable region of the immunoglobulin heavy and light chain genes. - Bm5 B lymphocyte - Bm5 B-cell - Bm5 B-lymphocyte - cell - Bm5 B cells are also reportedly CD10-positive, CD23-negative, CD38-negative, CD39-positive, CD44-positive, CD71-positive, and CD77-negative. - Bm5 B cell - - - - - A memory B cell arising in the germinal center that is IgD-negative and has undergone somatic mutation of the variable region of the immunoglobulin heavy and light chain genes. - GOC:dsd - GOC:msz - GOC:tfm - GO_REF:0000031 - PMID:18432934 - PMID:8006591 - + @@ -19208,25 +7785,7 @@ radial glial cells acting as neural progenitors throughout life. - A mature B cell that produces cytokines that can influence CD4 T cell differentiation. - B effector cell - effector B cell - effector B lymphocyte - effector B-cell - effector B-lymphocyte - cell - Be cell - - - - - A mature B cell that produces cytokines that can influence CD4 T cell differentiation. - GOC:msz - GOC:tfm - GO_REF:0000031 - PMID:11101868 - PMID:20224569 - + @@ -19234,31 +7793,7 @@ radial glial cells acting as neural progenitors throughout life. - A mature B cell that has the phenotype CD1d-positive and expresses interleukin-10. This cell type has been associated with suppression of chronic inflammatory responses and T cell responses. - B(reg) - B10 cell - Breg - regulatory B lymphocyte - regulatory B-cell - regulatory B-lymphocyte - cell - Regulatory B cells reportedly represent 1-2% of the spleen and 7-8% of the peritoneal B220-positive cells in mice. They are also found in the bone marrow, lymph node, and blood of mice. These cells are also reportedly capable of secreting IL-10 and are reportedly CD5-positive, CD21-positive, CD24-positive, CD93-negative, B220-positive, IgM-positive, and IgD-positive. - regulatory B cell - - - - - A mature B cell that has the phenotype CD1d-positive and expresses interleukin-10. This cell type has been associated with suppression of chronic inflammatory responses and T cell responses. - GOC:dsd - GOC:msz - GOC:tfm - GO_REF:0000031 - MESH:D060151 - PMID:11869683 - PMID:18482568 - PMID:20224569 - PMID:20809522 - + @@ -19266,33 +7801,7 @@ radial glial cells acting as neural progenitors throughout life. - An unswitched memory B cell is a memory B cell that has the phenotype IgM-positive, IgD-positive, CD27-positive, CD138-negative, IgG-negative, IgE-negative, and IgA-negative. - IgD+ memory B cell - unswitched memory B lymphocyte - unswitched memory B-cell - unswitched memory B-lymphocyte - cell - This cell type is compatible with the HIPC Lyoplate markers for 'IgD+ memory B cell'. Per DSD: Unswitched memory B cells are also reportedly CD48-positive, CD84-positive, CD229-positive, and CD352-positive. - unswitched memory B cell - - - - - An unswitched memory B cell is a memory B cell that has the phenotype IgM-positive, IgD-positive, CD27-positive, CD138-negative, IgG-negative, IgE-negative, and IgA-negative. - GOC:add - GOC:dsd - GOC:rhs - GO_REF:0000031 - ISBN:0781765196 - PMID:20933013 - PMID:22343568 - - - - - IgD+ memory B cell - PMID:22343568 - + @@ -19300,28 +7809,7 @@ radial glial cells acting as neural progenitors throughout life. - An IgM memory B cell is an unswitched memory B cell with the phenotype IgM-positive and IgD-negative. - IgM memory B lymphocyte - IgM memory B-cell - IgM memory B-lymphocyte - memory IgM B cell - memory IgM B lymphocyte - memory IgM B-cell - memory IgM B-lymphocyte - cell - IgM memory B cells are also reportedly CD1c-positive, CD95-positive, CD80-positive, CD84-positive, CD86-positive, CD150-negative, CD229-positive, CD289-positive, and CD290-positive. Transcription factors: Notch2-positive, PAX5-positive, SpiB-positive, Ets1-positive, and OBF1-positive. - IgM memory B cell - - - - - An IgM memory B cell is an unswitched memory B cell with the phenotype IgM-positive and IgD-negative. - GOC:dsd - GOC:rhs - GO_REF:0000031 - ISBN:0781765196 - PMID:19447676 - + @@ -19329,26 +7817,7 @@ radial glial cells acting as neural progenitors throughout life. - A class switched memory B cell is a memory B cell that has undergone Ig class switching and therefore is IgM-negative on the cell surface. These cells are CD27-positive and have either IgG, IgE, or IgA on the cell surface. - class switched memory B lymphocyte - class switched memory B-cell - class switched memory B-lymphocyte - cell - Per DSD: Class switched memory B cells are also reportedly CD48-positive, CD229-positive, and CD352-positive. - class switched memory B cell - - - - - A class switched memory B cell is a memory B cell that has undergone Ig class switching and therefore is IgM-negative on the cell surface. These cells are CD27-positive and have either IgG, IgE, or IgA on the cell surface. - GOC:add - GOC:dsd - GOC:rhs - GO_REF:0000031 - ISBN:0781765196 - PMID:20933013 - PMID:9295047 - + @@ -19356,27 +7825,7 @@ radial glial cells acting as neural progenitors throughout life. - A class switched memory B cell that expresses IgA. - IgA memory B lymphocyte - IgA memory B-cell - IgA memory B-lymphocyte - memory IgA B cell - memory IgA B lymphocyte - memory IgA B-cell - memory IgA B-lymphocyte - cell - IgA memory B cell are also reportedly RORalpha-positive. - IgA memory B cell - - - - - A class switched memory B cell that expresses IgA. - GOC:dsd - GOC:msz - GO_REF:0000031 - ISBN:0781765196 - + @@ -19384,20 +7833,7 @@ radial glial cells acting as neural progenitors throughout life. - A fully differentiated plasma cell that lives for years, as opposed to months, secretes immunoglobulin, and has the phenotype weakly CD19-positive, CD20-negative, CD38-negative, strongly CD138-positive, MHC Class II-negative, surface immunoglobulin-negative, IgD-negative, and strongly CXCR4-positive. The majority of these cells of this type reside in the bone marrow. - cell - long lived plasma cell - - - - A fully differentiated plasma cell that lives for years, as opposed to months, secretes immunoglobulin, and has the phenotype weakly CD19-positive, CD20-negative, CD38-negative, strongly CD138-positive, MHC Class II-negative, surface immunoglobulin-negative, IgD-negative, and strongly CXCR4-positive. The majority of these cells of this type reside in the bone marrow. - GOC:msz - GOC:tfm - GO_REF:0000031 - ISBN:9780781765190 - PMID:16014527 - @@ -19405,18 +7841,7 @@ radial glial cells acting as neural progenitors throughout life. - A fully differentiated plasma cell that lives for months. - cell - short lived plasma cell - - - - A fully differentiated plasma cell that lives for months. - GOC:msz - GO_REF:0000031 - PMID:16014527 - @@ -19424,18 +7849,7 @@ radial glial cells acting as neural progenitors throughout life. - A short lived plasma cell that secretes IgA. These cells may be found in the bone marrow as well as in the mucosal immune system. - cell - IgA short lived plasma cell - - - - A short lived plasma cell that secretes IgA. These cells may be found in the bone marrow as well as in the mucosal immune system. - GOC:msz - GO_REF:0000031 - ISBN:781735149 - @@ -19443,18 +7857,7 @@ radial glial cells acting as neural progenitors throughout life. - A short lived plasma cell that secretes IgG. - cell - IgG short lived plasma cell - - - - A short lived plasma cell that secretes IgG. - GOC:msz - GO_REF:0000031 - ISBN:781735149 - @@ -19462,18 +7865,7 @@ radial glial cells acting as neural progenitors throughout life. - A short lived plasma cell that secretes IgM. - cell - IgM short lived plasma cell - - - - A short lived plasma cell that secretes IgM. - GOC:msz - GO_REF:0000031 - ISBN:781735149 - @@ -19481,25 +7873,7 @@ radial glial cells acting as neural progenitors throughout life. - An IgG memory B cell is a class switched memory B cell that is class switched and expresses IgG on the cell surface. - IgG memory B lymphocyte - IgG memory B-cell - IgG memory B-lymphocyte - memory IgG B cell - memory IgG B lymphocyte - memory IgG B-cell - memory IgG B-lymphocyte - cell - IgG memory B cell - - - - - An IgG memory B cell is a class switched memory B cell that is class switched and expresses IgG on the cell surface. - GOC:rhs - GO_REF:0000031 - ISBN:0781765196 - + @@ -19508,22 +7882,7 @@ radial glial cells acting as neural progenitors throughout life. - An activated mature (naive or memory) B cell that is secreting immunoglobulin, typified by being CD27-positive, CD38-positive, CD138-negative. - FMA:84371 - cell - This cell type is compatible with the HIPC Lyoplate markers for 'plasmablast'. Plasmablasts are also reportedly CD48-positive, CD63-positive, CD229-positive, CD270-positive, CD319-positive, CD352-positive, CD361-positive, and IgD-negative. - plasmablast - - - - An activated mature (naive or memory) B cell that is secreting immunoglobulin, typified by being CD27-positive, CD38-positive, CD138-negative. - GOC:dsd - GOC:msz - GOC:tfm - GO_REF:0000031 - PMCID:PMC2673126 - @@ -19531,25 +7890,7 @@ radial glial cells acting as neural progenitors throughout life. - A memory B cell with the phenotype IgD-negative and CD27-negative. - dn memory B cell - dn memory B lymphocyte - dn memory B-cell - dn memory B-lymphocyte - double negative memory B lymphocyte - double negative memory B-cell - double negative memory B-lymphocyte - cell - double negative memory B cell - - - - - A memory B cell with the phenotype IgD-negative and CD27-negative. - GOC:msz - GOC:tfm - GO_REF:0000031 - + @@ -19557,17 +7898,7 @@ radial glial cells acting as neural progenitors throughout life. - A plasmablast that secretes IgG. - cell - IgG plasmablast - - - - A plasmablast that secretes IgG. - GOC:msz - GO_REF:0000031 - @@ -19575,17 +7906,7 @@ radial glial cells acting as neural progenitors throughout life. - A plasmablast that secretes IgM. - cell - IgM plasmablast - - - - A plasmablast that secretes IgM. - GOC:msz - GO_REF:0000031 - @@ -19593,17 +7914,7 @@ radial glial cells acting as neural progenitors throughout life. - A plasmablast that secretes IgA. - cell - IgA plasmablast - - - - A plasmablast that secretes IgA. - GOC:msz - GO_REF:0000031 - @@ -19611,18 +7922,7 @@ radial glial cells acting as neural progenitors throughout life. - A fully differentiated plasma cell that secretes IgG. - cell - IgG plasma cell - - - - A fully differentiated plasma cell that secretes IgG. - GOC:msz - GO_REF:0000031 - ISBN:781735149 - @@ -19630,18 +7930,7 @@ radial glial cells acting as neural progenitors throughout life. - A fully differentiated plasma cell that secretes IgM. - cell - IgM plasma cell - - - - A fully differentiated plasma cell that secretes IgM. - GOC:msz - GO_REF:0000031 - ISBN:781735149 - @@ -19649,18 +7938,7 @@ radial glial cells acting as neural progenitors throughout life. - A fully differentiated plasma cell that secretes IgA. - cell - IgA plasma cell - - - - A fully differentiated plasma cell that secretes IgA. - GOC:msz - GO_REF:0000031 - ISBN:781735149 - @@ -19669,24 +7947,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell of a hematopoietic lineage. - BTO:0000574 - CALOHA:TS-2017 - FMA:70366 - FMA:83598 - haematopoietic cell - haemopoietic cell - hemopoietic cell - cell - hematopoietic cell - - - - - A cell of a hematopoietic lineage. - GOC:add - GO_REF:0000031 - + @@ -19694,21 +7955,7 @@ radial glial cells acting as neural progenitors throughout life. - CD11c-low plasmacytoid dendritic cell is a leukocyte that is CD11c-low, CD45R-positive, GR1-positive and CD11b-negative. - cell - Originally described in the dendritic cell ontology (DC_CL:0000001)(PMID:19243617). These cells are CD281-positive (TLR1), CD282-positive (TLR2), CD285-positive (TLR5), CD286-positive (TLR6), and CD288-positive (TLR8). - CD11c-low plasmacytoid dendritic cell - - - - CD11c-low plasmacytoid dendritic cell is a leukocyte that is CD11c-low, CD45R-positive, GR1-positive and CD11b-negative. - GOC:amm - GOC:dsd - GO_REF:0000031 - PMID:15771572 - PMID:17850486 - @@ -19716,26 +7963,7 @@ radial glial cells acting as neural progenitors throughout life. - Conventional dendritic cell is a dendritic cell that is CD11c-high. - interdigitating cell - veiled cell - FMA:84191 - DC1 - cDC - dendritic reticular cell - type 1 DC - cell - Originally described in the dendritic cell ontology (DC_CL:0000003)(PMID:19243617) These cells are also CD20-negative, MHCII-positive. - conventional dendritic cell - - - - - Conventional dendritic cell is a dendritic cell that is CD11c-high. - GOC:amm - GO_REF:0000031 - PMID:17850486 - + @@ -19743,21 +7971,7 @@ radial glial cells acting as neural progenitors throughout life. - CD11c-negative plasmacytoid dendritic cell is a leukocyte is CD11c-negative, CD45RA-positive, CD85g-positive(ILT7), CD123-positive, CD303-positive. - CD303-positive dendritic cell - cell - Originally described in the dendritic cell ontology (DC_CL:0000004)(PMID:19243617). These cells are CD281-positive (TLR1), CD286-positive (TLR6), and CD290-positive (TLR10). - CD11c-negative plasmacytoid dendritic cell - - - - CD11c-negative plasmacytoid dendritic cell is a leukocyte is CD11c-negative, CD45RA-positive, CD85g-positive(ILT7), CD123-positive, CD303-positive. - GOC:amm - GO_REF:0000031 - PMID:15771572 - PMID:17850486 - @@ -19766,20 +7980,7 @@ radial glial cells acting as neural progenitors throughout life. - Immature CD11c-low plasmacytoid dendritic cell is a CD11c-low plasmacytoid dendritic cell that is CD80-low and CD86-low. - cell - Originally described in the dendritic cell ontology (DC_CL:0000006)(PMID:19243617). - immature CD11c-low plasmacytoid dendritic cell - - - - Immature CD11c-low plasmacytoid dendritic cell is a CD11c-low plasmacytoid dendritic cell that is CD80-low and CD86-low. - GOC:amm - GO_REF:0000031 - PMID:15771572 - PMID:17850486 - @@ -19788,20 +7989,7 @@ radial glial cells acting as neural progenitors throughout life. - Mature CD11c-low plasmacytoid dendritic cell is a CD11c-low plasmacytoid dendritic cell that is CD83-high and is CD80-positive, CD86-positive, and MHCII-positive. - cell - Originally described in the dendritic cell ontology (DC_CL:0000007)(PMID:19243617). - mature CD11c-low plasmacytoid dendritic cell - - - - Mature CD11c-low plasmacytoid dendritic cell is a CD11c-low plasmacytoid dendritic cell that is CD83-high and is CD80-positive, CD86-positive, and MHCII-positive. - GOC:amm - GO_REF:0000031 - PMID:15771572 - PMID:17850486 - @@ -19809,20 +7997,7 @@ radial glial cells acting as neural progenitors throughout life. - Immature CD11c-negative plasmacytoid dendritic cell is a CD11c-negative plasmacytoid dendritic cell is CD80-negative, CD86-low and MHCII-low. - cell - Originally described in the dendritic cell ontology (DC_CL:0000008)(PMID:19243617). - immature CD11c-negative plasmacytoid dendritic cell - - - - Immature CD11c-negative plasmacytoid dendritic cell is a CD11c-negative plasmacytoid dendritic cell is CD80-negative, CD86-low and MHCII-low. - GOC:amm - GO_REF:0000031 - PMID:15771572 - PMID:17850486 - @@ -19830,10 +8005,6 @@ radial glial cells acting as neural progenitors throughout life. - CD71-positive common myeloid precursor OR CD7-negative lymphoid precursor OR CD7-positive lymphoid - cell - Originally described in the dendritic cell ontology (DC_CL:1100000)(PMID:19243617). - CD34-positive, CD38-positive common myeloid progenitor OR CD34-positive, CD38-positive common lymphoid progenitor @@ -19842,20 +8013,7 @@ radial glial cells acting as neural progenitors throughout life. - Mature CD11c-negative plasmacytoid dendritic cell is a CD11c-negative plasmacytoid dendritic cell is CD80-high, CD86-high, MHCII-high and is CD83-positive. - cell - Originally described in the dendritic cell ontology (DC_CL:0000009)(PMID:19243617). - mature CD11c-negative plasmacytoid dendritic cell - - - - Mature CD11c-negative plasmacytoid dendritic cell is a CD11c-negative plasmacytoid dendritic cell is CD80-high, CD86-high, MHCII-high and is CD83-positive. - GOC:amm - GO_REF:0000031 - PMID:15771572 - PMID:17850486 - @@ -19864,20 +8022,7 @@ radial glial cells acting as neural progenitors throughout life. - Immature CD8_alpha-negative CD11b-positive dendritic cell is a CD8_alpha-negative CD11b-positive dendritic cell that is CD80-low, CD86-low, and MHCII-low. - cell - Originally described in the dendritic cell ontology (DC_CL:0000010)(PMID:19243617). - immature CD8_alpha-negative CD11b-positive dendritic cell - - - - Immature CD8_alpha-negative CD11b-positive dendritic cell is a CD8_alpha-negative CD11b-positive dendritic cell that is CD80-low, CD86-low, and MHCII-low. - GOC:amm - GOC:tfm - GO_REF:0000031 - PMCID:PMC2346585 - @@ -19886,22 +8031,7 @@ radial glial cells acting as neural progenitors throughout life. - CD8_alpha-negative CD11b-negative dendritic cell is a conventional dendritic cell that is CD11b-negative, CD4-negative CD8_alpha-negative and is CD205-positive. This cell is able to cross- present antigen to CD8-alpha-positive T cells. - DC.8-4-11b- - triple negative dendritic cell - cell - These markers are associated with mouse cells. Originally described in the dendritic cell ontology (DC_CL:0000011)(PMID:19243617). - CD8_alpha-negative CD11b-negative dendritic cell - - - - CD8_alpha-negative CD11b-negative dendritic cell is a conventional dendritic cell that is CD11b-negative, CD4-negative CD8_alpha-negative and is CD205-positive. This cell is able to cross- present antigen to CD8-alpha-positive T cells. - GOC:amm - GO_REF:0000031 - PMCID:PMC2346585 - http:www.immgen.org/index_content.html - @@ -19910,21 +8040,7 @@ radial glial cells acting as neural progenitors throughout life. - CD8_alpha-negative CD11b-positive dendritic cell is a conventional dendritic cell that is CD11b-positive, CD4-positive and is CD205-negative and CD8_alpha-negative. - DC.4+ - cell - Defined as having a disposition to secreting anti-inflammatory cytokines. These markers are associated with mouse cells. Originally described in the dendritic cell ontology (DC_CL:0000012)(PMID:19243617). - CD4-positive CD11b-positive dendritic cell - - - - CD8_alpha-negative CD11b-positive dendritic cell is a conventional dendritic cell that is CD11b-positive, CD4-positive and is CD205-negative and CD8_alpha-negative. - GOC:amm - GOC:tfm - GO_REF:0000031 - PMCID:PMC2346585 - @@ -19933,21 +8049,7 @@ radial glial cells acting as neural progenitors throughout life. - CD8_alpha-positive CD11b-negative dendritic cell is a conventional dendritic cell that is CD11b-negative, CD4-negative and is CD205-positive and CD8_alpha-positive. - DC.8+ - cell - Cells are defined as having a disposition to secreting inflammatory cytokines. Originally described in the dendritic cell ontology (DC_CL:0000013)(PMID:19243617). - CD8_alpha-positive CD11b-negative dendritic cell - - - - CD8_alpha-positive CD11b-negative dendritic cell is a conventional dendritic cell that is CD11b-negative, CD4-negative and is CD205-positive and CD8_alpha-positive. - GOC:amm - GOC:tfm - GO_REF:0000031 - PMCID:PMC2346585 - @@ -19956,19 +8058,7 @@ radial glial cells acting as neural progenitors throughout life. - Immature CD8_alpha-negative CD11b-negative dendritic cell is a CD8_alpha-negative CD11b-negative dendritic cell that is CD80-low, CD86-low, and MHCII-low. - cell - These markers are associated with mouse cells. Originally described in the dendritic cell ontology (DC_CL:0000014)(PMID:19243617). - immature CD8_alpha-negative CD11b-negative dendritic cell - - - - Immature CD8_alpha-negative CD11b-negative dendritic cell is a CD8_alpha-negative CD11b-negative dendritic cell that is CD80-low, CD86-low, and MHCII-low. - GOC:amm - GO_REF:0000031 - PMCID:PMC2346585 - @@ -19977,20 +8067,7 @@ radial glial cells acting as neural progenitors throughout life. - Mature CD8_alpha-negative CD11b-negative dendritic cell is a CD8_alpha-negative CD11b-negative dendritic cell that is CD80-high, CD86-high, MHCII-high and is CD83-positive. - cell - These markers are associated with mouse cells. Defined as having a disposition to secretion of anti-inflammatory cytokines. Originally described in the dendritic cell ontology (DC_CL:0000015)(PMID:19243617). - mature CD8_alpha-negative CD11b-negative dendritic cell - - - - Mature CD8_alpha-negative CD11b-negative dendritic cell is a CD8_alpha-negative CD11b-negative dendritic cell that is CD80-high, CD86-high, MHCII-high and is CD83-positive. - GOC:amm - GOC:tfm - GO_REF:0000031 - PMCID:PMC2346585 - @@ -19999,20 +8076,7 @@ radial glial cells acting as neural progenitors throughout life. - Mature CD8_alpha-negative CD11b-positive dendritic cell is a CD8_alpha-negative CD11b-positive dendritic cell that is CD80-high, CD86-high, MHCII-high and is CD83-positive. - cell - Originally described in the dendritic cell ontology (DC_CL:0000016)(PMID:19243617). - mature CD8_alpha-negative CD11b-positive dendritic cell - - - - Mature CD8_alpha-negative CD11b-positive dendritic cell is a CD8_alpha-negative CD11b-positive dendritic cell that is CD80-high, CD86-high, MHCII-high and is CD83-positive. - GOC:amm - GOC:tfm - GO_REF:0000031 - PMCID:PMC2346585 - @@ -20021,20 +8085,7 @@ radial glial cells acting as neural progenitors throughout life. - Immature CD8_alpha-positive CD11b-negative dendritic cell is a CD8_alpha-positive CD11b-negative dendritic cell that is CD80-low, CD86-low, and MHCII-low. - cell - Originally described in the dendritic cell ontology (DC_CL:0000017)(PMID:19243617). - immature CD8_alpha-positive CD11b-negative dendritic cell - - - - Immature CD8_alpha-positive CD11b-negative dendritic cell is a CD8_alpha-positive CD11b-negative dendritic cell that is CD80-low, CD86-low, and MHCII-low. - GOC:amm - GOC:tfm - GO_REF:0000031 - PMCID:PMC2346585 - @@ -20043,19 +8094,7 @@ radial glial cells acting as neural progenitors throughout life. - Mature CD8_alpha-positive CD11b-negative dendritic cell is a CD8_alpha-positive CD11b-negative dendritic cell that is CD80-high, CD86-high, MHCII-high and is CD83-positive. - cell - Originally described in the dendritic cell ontology (DC_CL:0000018)(PMID:19243617). - mature CD8_alpha-positive CD11b-negative dendritic cell - - - - Mature CD8_alpha-positive CD11b-negative dendritic cell is a CD8_alpha-positive CD11b-negative dendritic cell that is CD80-high, CD86-high, MHCII-high and is CD83-positive. - GOC:amm - GO_REF:0000031 - PMCID:PMC2346585 - @@ -20063,20 +8102,7 @@ radial glial cells acting as neural progenitors throughout life. - Dermal dendritic cell is a conventional dendritic cell that is CD11b-positive, CD205-positive and CD8 alpha-negative. - BTO:0004812 - cell - Originally described in the dendritic cell ontology (DC_CL:0000019)(PMID:19243617). These cells are also CD281-positive (TLR1), CD282-positive (TLR2), CD283-positive (TLR3), CD284-positive (TLR4), CD285-positive (TLR5), CD288-positive (TLR8), and CD289-positive (TLR9). - dermal dendritic cell - - - - Dermal dendritic cell is a conventional dendritic cell that is CD11b-positive, CD205-positive and CD8 alpha-negative. - GOC:amm - GO_REF:0000031 - PMCID:PMC2346585 - @@ -20084,19 +8110,7 @@ radial glial cells acting as neural progenitors throughout life. - Interstitial dendritic cell is a conventional dendritic cell that is CD11b-positive, CD1a-positive, CD206-positive, CD209-positive, and CD36-positive. - cell - Originally described in the dendritic cell ontology (DC_CL:0000020)(PMID:19243617). These cells are also CD281-positive (TLR1), CD282-positive (TLR2), CD283-positive (TLR3), CD284-positive (TLR4), CD286-positive (TLR6), CD288-positive (TLR8), and CD290-positive (TLR10). - interstitial dendritic cell - - - - Interstitial dendritic cell is a conventional dendritic cell that is CD11b-positive, CD1a-positive, CD206-positive, CD209-positive, and CD36-positive. - GOC:amm - GO_REF:0000031 - PMID:17850486 - @@ -20104,24 +8118,8 @@ radial glial cells acting as neural progenitors throughout life. - A hematopoietic stem cell that has plasma membrane part Kit-positive, SCA-1-positive, CD150-positive and CD34-negative. - LSK stem cell - Sca1-positive hematopoietic stem cell - cell - Cell markers are associated with mouse hematopoietic stem cell. Originally described in the dendritic cell ontology (DC_CL:0000043)(PMID:19243617). - Kit and Sca1-positive hematopoietic stem cell - - - - - A hematopoietic stem cell that has plasma membrane part Kit-positive, SCA-1-positive, CD150-positive and CD34-negative. - GOC:add - GOC:amm - GOC:tfm - GO_REF:0000031 - PMID:17952047 - PMID:19022770 - + + @@ -20130,19 +8128,7 @@ radial glial cells acting as neural progenitors throughout life. - Immature dermal dendritic cell is a dermal dendritic cell that is CD80-low, CD86-low, and MHCII-low. - cell - Originally described in the dendritic cell ontology (DC_CL:0000022)(PMID:19243617). - immature dermal dendritic cell - - - - Immature dermal dendritic cell is a dermal dendritic cell that is CD80-low, CD86-low, and MHCII-low. - GOC:amm - GO_REF:0000031 - PMCID:PMC2346585 - @@ -20151,19 +8137,7 @@ radial glial cells acting as neural progenitors throughout life. - Mature dermal dendritic cell is a dermal dendritic cell that is CD80-high, CD86-high, MHCII-high and is CD83-positive. - cell - Originally described in the dendritic cell ontology (DC_CL:0000023)(PMID:19243617). - mature dermal dendritic cell - - - - Mature dermal dendritic cell is a dermal dendritic cell that is CD80-high, CD86-high, MHCII-high and is CD83-positive. - GOC:amm - GO_REF:0000031 - PMCID:PMC2346585 - @@ -20172,20 +8146,7 @@ radial glial cells acting as neural progenitors throughout life. - Immature interstitial dendritic cell is a interstitial dendritic cell that is CD80-low, CD86-low, and MHCII-low. - cell - Originally described in the dendritic cell ontology (DC_CL:0000024)(PMID:19243617). - immature interstitial dendritic cell - - - - Immature interstitial dendritic cell is a interstitial dendritic cell that is CD80-low, CD86-low, and MHCII-low. - GOC:amm - GOC:tfm - GO_REF:0000031 - PMID:17850486 - @@ -20193,9 +8154,6 @@ radial glial cells acting as neural progenitors throughout life. - cell - Originally described in the dendritic cell ontology (DC_CL:1110000)(PMID:19243617). - CD7-negative lymphoid progenitor OR granulocyte monocyte progenitor @@ -20205,20 +8163,7 @@ radial glial cells acting as neural progenitors throughout life. - Mature interstitial dendritic cell is a interstitial dendritic cell that is CD80-high, CD86-high, MHCII-high and is CD83-positive. - cell - Originally described in the dendritic cell ontology (DC_CL:0000025)(PMID:19243617). - mature interstitial dendritic cell - - - - Mature interstitial dendritic cell is a interstitial dendritic cell that is CD80-high, CD86-high, MHCII-high and is CD83-positive. - GOC:amm - GOC:tfm - GO_REF:0000031 - PMID:17850486 - @@ -20226,20 +8171,7 @@ radial glial cells acting as neural progenitors throughout life. - CD1a-positive Langerhans cell is a Langerhans_cell that is CD1a-positive and CD324-positive. - CD1a-LC - cell - These markers are associated with human cells. Originally described in the dendritic cell ontology (DC_CL:0000026)(PMID:19243617). These cells are also CD281-positive (TLR1), CD282-positive (TLR2), CD284-positive (TLR4), CD286-positive (TLR6), CD287-positive (TLR7), and CD290-positive (TLR10). When activated, these cells are capable of producing IL-6, IL-8, and IL-15. - CD1a-positive Langerhans cell - - - - CD1a-positive Langerhans cell is a Langerhans_cell that is CD1a-positive and CD324-positive. - GOC:amm - GO_REF:0000031 - PMID:17850486 - @@ -20247,19 +8179,7 @@ radial glial cells acting as neural progenitors throughout life. - CD8_alpha-low Langerhans cell is a Langerhans cell that is CD205-high and is CD8_alpha-low. - cell - These markers are associated with mouse cells. Originally described in the dendritic cell ontology (DC_CL:0000027)(PMID:19243617). They are also CD205-high, CD281-positive (TLR1), CD282-positive (TLR2), CD283-positive (TLR3), CD285-positive (TLR5), CD286-positive (TLR6), and CD289-positive (TLR9). - CD8_alpha-low Langerhans cell - - - - CD8_alpha-low Langerhans cell is a Langerhans cell that is CD205-high and is CD8_alpha-low. - GOC:amm - GO_REF:0000031 - PMCID:PMC2346585 - @@ -20268,20 +8188,7 @@ radial glial cells acting as neural progenitors throughout life. - Immature CD1a-positive Langerhans cell is a CD1a-positive Langerhans cell that is CD80-low, CD86-low, and MHCII-low. - cell - Originally described in the dendritic cell ontology (DC_CL:0000028)(PMID:19243617). - immature CD1a-positive Langerhans cell - - - - Immature CD1a-positive Langerhans cell is a CD1a-positive Langerhans cell that is CD80-low, CD86-low, and MHCII-low. - GOC:amm - GOC:tfm - GO_REF:0000031 - PMID:17850486 - @@ -20290,20 +8197,7 @@ radial glial cells acting as neural progenitors throughout life. - Mature CD1a-positive Langerhans cell is a CD1a-positive Langerhans cell that is CD80-high, CD86-high, MHCII-high and is CD83-positive. - cell - Originally described in the dendritic cell ontology (DC_CL:0000029)(PMID:19243617). When activated, these cells produce IL-6, IL-8, and IL-15. - mature CD1a-positive Langerhans cell - - - - Mature CD1a-positive Langerhans cell is a CD1a-positive Langerhans cell that is CD80-high, CD86-high, MHCII-high and is CD83-positive. - GOC:amm - GOC:tfm - GO_REF:0000031 - PMID:17850486 - @@ -20312,20 +8206,7 @@ radial glial cells acting as neural progenitors throughout life. - Immature CD8_alpha-low Langerhans cell is a CD8_alpha-low Langerhans cell that is CD80-low, CD86-low, and MHCII-low. - cell - These markers are associated with mouse cells. Originally described in the dendritic cell ontology (DC_CL:0000030)(PMID:19243617). - immature CD8_alpha-low Langerhans cell - - - - Immature CD8_alpha-low Langerhans cell is a CD8_alpha-low Langerhans cell that is CD80-low, CD86-low, and MHCII-low. - GOC:amm - GOC:tfm - GO_REF:0000031 - PMCID:PMC2346585 - @@ -20333,9 +8214,6 @@ radial glial cells acting as neural progenitors throughout life. - cell - Originally described in the dendritic cell ontology (DC_CL:1111000)(PMID:19243617). - CD115-positive monocyte OR common dendritic progenitor @@ -20345,19 +8223,7 @@ radial glial cells acting as neural progenitors throughout life. - Mature CD8_alpha-low Langerhans cell is a CD8_alpha-low Langerhans cell that that is CD80-high, CD86-high, MHCII-high and is CD83-positive. - cell - These markers are associated with mouse cells. Originally described in the dendritic cell ontology (DC_CL:0000031)(PMID:19243617). - mature CD8_alpha-low Langerhans cell - - - - Mature CD8_alpha-low Langerhans cell is a CD8_alpha-low Langerhans cell that that is CD80-high, CD86-high, MHCII-high and is CD83-positive. - GOC:amm - GO_REF:0000031 - PMCID:PMC2346585 - @@ -20366,25 +8232,8 @@ radial glial cells acting as neural progenitors throughout life. - A common lymphoid progenitor that is CD10-positive, CD45RA-positive, CD34-positive and CD38-positive. - CD10-positive common lymphocyte precursor - CD10-positive common lymphocyte progenitor - CD10-positive common lymphoid precursor - cell - These markers are associated with human common lymphoid progenitors. Originally described in the dendritic cell ontology (DC_CL:0000032)(PMID:19243617). - CD34-positive, CD38-positive common lymphoid progenitor - - - - - A common lymphoid progenitor that is CD10-positive, CD45RA-positive, CD34-positive and CD38-positive. - GOC:add - GOC:amm - GOC:tfm - GO_REF:0000031 - PMCID:PMC2346585 - PMID:19022770 - + + @@ -20394,20 +8243,7 @@ radial glial cells acting as neural progenitors throughout life. - CD115-positive monocyte is a monocyte that is CD115-positive and CD11b-positive. - cell - These markers are associated with human cells. Originally described in the dendritic cell ontology (DC_CL:0000033)(PMID:19243617). - CD115-positive monocyte - - - - CD115-positive monocyte is a monocyte that is CD115-positive and CD11b-positive. - GOC:add - GOC:amm - GO_REF:0000031 - PMID:17952047 - @@ -20416,24 +8252,8 @@ radial glial cells acting as neural progenitors throughout life. - A common myeloid progenitor that is Kit-positive and CD34-positive, Il7ra-negative, and is SCA1-low and Fcgr2-low and Fcgr3-low. - CD117-positive common myeloid precursor - cell - Markers are associated with mouse cells. Originally described in the dendritic cell ontology (DC_CL:0000034)(PMID:19243617). - Kit-positive, CD34-positive common myeloid progenitor - - - - - A common myeloid progenitor that is Kit-positive and CD34-positive, Il7ra-negative, and is SCA1-low and Fcgr2-low and Fcgr3-low. - GOC:add - GOC:amm - GOC:tfm - GO_REF:0000031 - PMID:1261582 - PMID:17952047 - http://www.immgen.org/index_content.html - + + @@ -20441,34 +8261,7 @@ radial glial cells acting as neural progenitors throughout life. - CD133-positive hematopoietic stem cell is a hematopoietic stem cell that is CD34-positive, CD90-positive, and CD133-positive. - CALOHA:TS-0448 - FMA:86475 - CD133-positive hematopoietic stem cell - cell - Cell markers are associated with human hematopoietic stem cells. Originally described in the dendritic cell ontology (DC_CL:0000035)(PMID:19243617). - CD34-positive, CD38-negative hematopoietic stem cell - - - - - CD133-positive hematopoietic stem cell is a hematopoietic stem cell that is CD34-positive, CD90-positive, and CD133-positive. - GOC:add - GOC:amm - GOC:tfm - GO_REF:0000031 - PMID:10430905 - PMID:11750107 - PMID:16551251 - PMID:20024907 - PMID:9389721 - - - - - CD133-positive hematopoietic stem cell - PMID:16140871 - + @@ -20477,25 +8270,7 @@ radial glial cells acting as neural progenitors throughout life. - A common lymphoid progenitor that is Kit-low, FLT3-positive, IL7ralpha-positive, and SCA1-low. - CD217-positive common lymphocyte precursor - CD217-positive common lymphocyte progenitor - CD217-positive common lymphoid precursor - cell - Markers are associated with mouse cells. - Kit-positive, Sca1-positive common lymphoid progenitor - - - - - A common lymphoid progenitor that is Kit-low, FLT3-positive, IL7ralpha-positive, and SCA1-low. - GOC:add - GOC:amm - GOC:tfm - GO_REF:0000031 - PMID:17952047 - http://www.immgen.org/index_content.html - + @@ -20504,22 +8279,7 @@ radial glial cells acting as neural progenitors throughout life. - A common myeloid progenitor that is CD34-positive, CD38-positive, IL3ra-low, CD10-negative, CD7-negative, CD45RA-negative, and IL-5Ralpha-negative. - CD71-positive common myeloid precursor - cell - Markers are associated with human cell type. Originally described in the dendritic cell ontology (DC_CL:0000038)(PMID:19243617). - CD34-positive, CD38-positive common myeloid progenitor - - - - A common myeloid progenitor that is CD34-positive, CD38-positive, IL3ra-low, CD10-negative, CD7-negative, CD45RA-negative, and IL-5Ralpha-negative. - GOC:add - GOC:amm - GO_REF:0000031 - PMCID:PMC2626675 - PMID:16551251 - @@ -20528,20 +8288,7 @@ radial glial cells acting as neural progenitors throughout life. - CD7-negative lymphoid progenitor cell is a lymphoid progenitor cell that is CD34-positive, CD7-negative and CD45RA-negative. - CD7-negative lymphoid precursor - cell - These markers are associated with human cells. Originally described in the dendritic cell ontology (DC_CL:0000039)(PMID:19243617). - CD7-negative lymphoid progenitor cell - - - - CD7-negative lymphoid progenitor cell is a lymphoid progenitor cell that is CD34-positive, CD7-negative and CD45RA-negative. - GOC:amm - GO_REF:0000031 - PMID:16551251 - @@ -20549,22 +8296,7 @@ radial glial cells acting as neural progenitors throughout life. - CD7-positive lymphoid progenitor cell is a lymphoid progenitor cell that is CD34-positive, CD7-positive and is CD45RA-negative. - CD7-positive lymphoid precursor - cell - These markers are associated with human cells. Originally described in the dendritic cell ontology (DC_CL:0000040)(PMID:19243617). - CD7-positive lymphoid progenitor cell - - - - CD7-positive lymphoid progenitor cell is a lymphoid progenitor cell that is CD34-positive, CD7-positive and is CD45RA-negative. - GOC:amm - GOC:tfm - GO_REF:0000031 - PMID:16551251 - PMID:19491395 - @@ -20573,37 +8305,7 @@ radial glial cells acting as neural progenitors throughout life. - Common dendritic precursor is a hematopoietic progenitor cell that is CD117-low, CD135-positive, CD115-positive and lacks plasma membrane parts for hematopoietic lineage markers. - CDP - common dendritic precursor - pro-DCs - cell - Surface markers are for mouse cells. Originally described in the dendritic cell ontology (DC_CL:0000041) CDP are reportedly CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD11c-positive, CD14-negative, CD19-negative, CD20-negative, CD56-negative, B220-negative, Ly6g-negative, MHCII-positive, and Ter119-negative. (PMID:19243617). - common dendritic progenitor - - - - - Common dendritic precursor is a hematopoietic progenitor cell that is CD117-low, CD135-positive, CD115-positive and lacks plasma membrane parts for hematopoietic lineage markers. - GOC:amm - GOC:tfm - GO_REF:0000031 - PMID:16551251 - PMID:17922016 - PMID:19286519 - - - - - CDP - PMID:21219184 - - - - - pro-DCs - PMID:21219184 - + @@ -20611,9 +8313,6 @@ radial glial cells acting as neural progenitors throughout life. - cell - Originally described in the dendritic cell ontology (DC_CL:1111100)(PMID:19243617). - CD117-positive common myeloid progenitor OR CD217-positive common lymphoid progenitor @@ -20623,17 +8322,7 @@ radial glial cells acting as neural progenitors throughout life. - Granule cell that is part of the cerebellum. - BTO:0004278 - cell - cerebellar granule cell - - - - Granule cell that is part of the cerebellum. - GOC:mah - @@ -20642,16 +8331,7 @@ radial glial cells acting as neural progenitors throughout life. - Granule cell that is part of the cerebral cortex. - cell - cortical granule cell - - - - Granule cell that is part of the cerebral cortex. - GOC:mah - @@ -20660,16 +8340,7 @@ radial glial cells acting as neural progenitors throughout life. - Granule cell that is part of the hippocampus. - cell - hippocampal granule cell - - - - Granule cell that is part of the hippocampus. - GOC:mah - @@ -20677,19 +8348,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell that is maintained or propagated in a controlled artificial environment for use in an investigation. - haendel - 2012-01-12T09:58:38Z - cell - 'In vitro', translating literally to 'in glass', typically refers to a controlled, often sterile, laboratory setting where cells or other specimens are placed by some agent for the purpose of studying or manipulating them as part of some research investigation. 'In vitro' is intended to contrast with 'native',which refers to cells or other biological entities that are found in a natural setting. It describes unicellular organisms removed from a natural environement and multicellular organism cells removed from an organism, or cells derived in culture from such displaced cells. - cell in vitro - - - - A cell that is maintained or propagated in a controlled artificial environment for use in an investigation. - ReO:mhb - @@ -20697,19 +8356,7 @@ radial glial cells acting as neural progenitors throughout life. - A connective tissue cell found in bone. - adiehl - 2011-11-16T04:28:16Z - cell - bone cell - - - - A connective tissue cell found in bone. - GOC:add - GO_REF:0000034 - @@ -20717,17 +8364,7 @@ radial glial cells acting as neural progenitors throughout life. - Osteoblast that is terminally differentiated, located adjacent to acellular or cellular bone tissue within periosteum, and is capable of mineralizing the matrix. - VSAO:0000116 - cl - terminally differentiated osteoblast - - - - Osteoblast that is terminally differentiated, located adjacent to acellular or cellular bone tissue within periosteum, and is capable of mineralizing the matrix. - VSAO:curator - @@ -20736,18 +8373,7 @@ radial glial cells acting as neural progenitors throughout life. - Osteoblast that is non-terminally differentiated and located in cellular bone tissue or under the periosteum in acellular bone. - VSAO:0000117 - cl - VSAO relationship simplified OBO_REL:integral_part_of VSAO:0000118 - non-terminally differentiated osteoblast - - - - Osteoblast that is non-terminally differentiated and located in cellular bone tissue or under the periosteum in acellular bone. - VSAO:curator - @@ -20755,29 +8381,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD8-positive alpha-beta-positive T cell with the phenotype CXCR3-positive and having suppressor function. They are capable of producing IL-10, suppressing proliferation, and suppressing IFN-gamma production. - CD8+CXCR3+ T cell - CD8+CXCR3+ T lymphocyte - CD8+CXCR3+ T(reg) - CD8+CXCR3+ T-cell - CD8+CXCR3+ T-lymphocyte - CD8+CXCR3+ Treg - CD8-positive, CXCR3-positive, T(reg) - CD8-positive, CXCR3-positive, Treg - CD8-positive, CXCR3-positive, alpha-beta regulatory T lymphocyte - CD8-positive, CXCR3-positive, alpha-beta regulatory T-cell - CD8-positive, CXCR3-positive, alpha-beta regulatory T-lymphocyte - cell - These cells may be the human equivalent of murine CD8-positive, CD122-positive alpha-beta regulatory T cell. They are also found in the CD45RA-negative and CD62L-positive fraction. - CD8-positive, CXCR3-positive, alpha-beta regulatory T cell - - - - - A CD8-positive alpha-beta-positive T cell with the phenotype CXCR3-positive and having suppressor function. They are capable of producing IL-10, suppressing proliferation, and suppressing IFN-gamma production. - GOC:dsd - PMID:19609979 - + @@ -20785,26 +8389,7 @@ radial glial cells acting as neural progenitors throughout life. - CD4-positive, alpha-beta T cell that produces IL-22. - T(H)-22 cell - Th22 T cell - Th22 T lymphocyte - Th22 T-cell - Th22 T-lymphocyte - Th22 cell - helper T cell type 22 - cell - TH22 cells are also reportedly CCR4-positive, CCR6-positive, CCR10-positive, CXCR3-negative. TH22 cells are reportedly capable of secreting IL-13. - T-helper 22 cell - - - - - CD4-positive, alpha-beta T cell that produces IL-22. - GOC:dsd - PMID:19578368 - PMID:19578369 - + @@ -20812,28 +8397,7 @@ radial glial cells acting as neural progenitors throughout life. - A recently activated CD4-positive, alpha-beta T cell with the phenotype HLA-DRA-positive, CD38-positive, CD69-positive, CD62L-negative, CD127-negative, and CD25-positive. - activated CD4+ T cell - activated CD4-positive, alpha-beta T lymphocyte, human - activated CD4-positive, alpha-beta T-cell, human - activated CD4-positive, alpha-beta T-lymphocyte, human - cell - This cell type is compatible with the HIPC Lyoplate markers for 'activated CD4+ T cell', but includes via logical inference from its parent additional markers known to be expressed on activated CD4+ T cells. The inclusion of HLA-DRA in the definition restricts this definition to human activated CD4+ T cells, as activated mouse T cells do not express MHC class II. - activated CD4-positive, alpha-beta T cell, human - - - - - A recently activated CD4-positive, alpha-beta T cell with the phenotype HLA-DRA-positive, CD38-positive, CD69-positive, CD62L-negative, CD127-negative, and CD25-positive. - GOC:add - PMID:22343568 - - - - - activated CD4+ T cell - PMID:22343568 - + @@ -20842,28 +8406,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD4-positive, alpha-beta T cell with the phenotype CCR7-negative, CD45RA-positive. - effector CD4+ T cell - effector CD4-positive, alpha-beta T lymphocyte - effector CD4-positive, alpha-beta T-cell - effector CD4-positive, alpha-beta T-lymphocyte - cell - This cell type is compatible with the HIPC Lyoplate markers for 'effector CD4+ T cell'. The functional characteristics of this cell type currently undefined in CL, which affects its proper placement within the hierarchy. - effector CD4-positive, alpha-beta T cell - - - - - A CD4-positive, alpha-beta T cell with the phenotype CCR7-negative, CD45RA-positive. - GOC:add - PMID:22343568 - - - - - effector CD4+ T cell - PMID:22343568 - + @@ -20872,28 +8415,7 @@ radial glial cells acting as neural progenitors throughout life. - A naive regulatory T cell with the phenotype CD4-positive, CD25-positive, CD127lo, CCR4-positive, and CD45RO-negative. - naive CCR4+ Treg - naive CCR4-positive regulatory T lymphocyte - naive CCR4-positive regulatory T-cell - naive CCR4-positive regulatory T-lymphocyte - cell - This cell type is compatible with the HIPC Lyoplate markers for 'naive CCR4+ Treg'. The definition is valid for human; its applicability for mouse and other species is unknown. - naive CCR4-positive regulatory T cell - - - - - A naive regulatory T cell with the phenotype CD4-positive, CD25-positive, CD127lo, CCR4-positive, and CD45RO-negative. - GOC:add - PMID:22343568 - - - - - naive CCR4+ Treg - PMID:22343568 - + @@ -20902,28 +8424,7 @@ radial glial cells acting as neural progenitors throughout life. - A memory regulatory T cell with phenotype CD4-positive, CD25-positive, CD127lo, CCR4-positive, and CD45RO-positive. - memory CCR4+ Treg - memory CCR4-positive regulatory T lymphocyte - memory CCR4-positive regulatory T-cell - memory CCR4-positive regulatory T-lymphocyte - cell - This cell type is compatible with the HIPC Lyoplate markers for 'memory CCR4+ Treg'. The definition is valid for human; its applicability for mouse and other species is unknown. - memory CCR4-positive regulatory T cell - - - - - A memory regulatory T cell with phenotype CD4-positive, CD25-positive, CD127lo, CCR4-positive, and CD45RO-positive. - GOC:add - PMID:22343568 - - - - - memory CCR4+ Treg - PMID:22343568 - + @@ -20931,28 +8432,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD4-positive, CD25-positive, alpha-beta regulatory T cell with the additional phenotype CCR4-positive. - CCR+ Treg - CD4-positive, CD25-positive, CCR4-positive, alpha-beta regulatory T lymphocyte - CD4-positive, CD25-positive, CCR4-positive, alpha-beta regulatory T-cell - CD4-positive, CD25-positive, CCR4-positive, alpha-beta regulatory T-lymphocyte - cell - This cell type is compatible with the HIPC Lyoplate markers for 'CCR4+ Treg'. The definition is valid for human; its applicability for mouse and other species is unknown. - CD4-positive, CD25-positive, CCR4-positive, alpha-beta regulatory T cell - - - - - A CD4-positive, CD25-positive, alpha-beta regulatory T cell with the additional phenotype CCR4-positive. - GOC:add - PMID:22343568 - - - - - CCR+ Treg - PMID:22343568 - + @@ -20960,28 +8440,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD4-positive, CD25-positive, CCR4-positive, alpha-beta T regulatory cell with the phenotype HLA-DRA-positive, indicating recent activation. - activated CCR4+ Treg - activated CD4-positive, CD25-positive, CCR4-positive, alpha-beta regulatory T lymphocyte - activated CD4-positive, CD25-positive, CCR4-positive, alpha-beta regulatory T-cell - activated CD4-positive, CD25-positive, CCR4-positive, alpha-beta regulatory T-lymphocyte - cell - This cell type is compatible with the HIPC Lyoplate markers for 'activated CCR4+ Treg'. The inclusion of HLA-DRA in the definition restricts this definition to human activated CD4+ T cells, as activated mouse T cells do not express MHC class II. - activated CD4-positive, CD25-positive, CCR4-positive, alpha-beta regulatory T cell, human - - - - - A CD4-positive, CD25-positive, CCR4-positive, alpha-beta T regulatory cell with the phenotype HLA-DRA-positive, indicating recent activation. - GOC:add - PMID:22343568 - - - - - activated CCR4+ Treg - PMID:22343568 - + @@ -20989,28 +8448,7 @@ radial glial cells acting as neural progenitors throughout life. - A recently activated CD8-positive, alpha-beta T cell with the phenotype HLA-DRA-positive, CD38-positive, CD69-positive, CD62L-negative, CD127-negative, CCR7-negative, and CD25-positive. - activated CD8+ T cell - activated CD8-positive, alpha-beta T lymphocyte, human - activated CD8-positive, alpha-beta T-cell, human - activated CD8-positive, alpha-beta T-lymphocyte, human - cell - This cell type is compatible with the HIPC Lyoplate markers for 'activated CD8+ T cell', but includes via logical inference from its parent additional markers known to be expressed on activated CD8+ T cells. The inclusion of HLA-DRA in the definition restricts this definition to human activated CD8+ T cells, as activated mouse T cells do not express MHC class II. - activated CD8-positive, alpha-beta T cell, human - - - - - A recently activated CD8-positive, alpha-beta T cell with the phenotype HLA-DRA-positive, CD38-positive, CD69-positive, CD62L-negative, CD127-negative, CCR7-negative, and CD25-positive. - GOC:add - PMID:22343568 - - - - - activated CD8+ T cell - PMID:22343568 - + @@ -21019,28 +8457,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD8-positive, alpha-beta T cell with the phenotype CCR7-negative, CD45RA-positive. - effector CD8+ T cell - effector CD8-positive, alpha-beta T lymphocyte - effector CD8-positive, alpha-beta T-cell - effector CD8-positive, alpha-beta T-lymphocyte - cell - This cell type is compatible with the HIPC Lyoplate markers for 'effector CD8+ T cell'. The functional characteristics of this cell type currently undefined in CL, which affects its proper placement within the hierarchy. - effector CD8-positive, alpha-beta T cell - - - - - A CD8-positive, alpha-beta T cell with the phenotype CCR7-negative, CD45RA-positive. - GOC:add - PMID:22343568 - - - - - effector CD8+ T cell - PMID:22343568 - + @@ -21048,28 +8465,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD4-positive, alpha-beta T cell that has the phenotype CXCR3-negative, CCR6-negative. - non-Th1/Th17 CD4+ T cell - CD4-positive, CXCR3-negative, CCR6-negative, alpha-beta T lymphocyte - CD4-positive, CXCR3-negative, CCR6-negative, alpha-beta T-cell - CD4-positive, CXCR3-negative, CCR6-negative, alpha-beta T-lymphocyte - cell - This cell type is compatible with the HIPC Lyoplate markers for 'non-Th1/Th17 CD4+ T cell'. Cells of this phenotype may include T-helper 2 T cells and some naive CD4+ T cells. - CD4-positive, CXCR3-negative, CCR6-negative, alpha-beta T cell - - - - - A CD4-positive, alpha-beta T cell that has the phenotype CXCR3-negative, CCR6-negative. - GOC:add - PMID:22343568 - - - - - non-Th1/Th17 CD4+ T cell - PMID:22343568 - + @@ -21077,28 +8473,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD8-positive, alpha-beta T cell that has the phenotype CXCR3-negative, CCR6-negative. - non-Tc1/Tc17 CD8+ T cell - CD8-positive, CXCR3-negative, CCR6-negative, alpha-beta T lymphocyte - CD8-positive, CXCR3-negative, CCR6-negative, alpha-beta T-cell - CD8-positive, CXCR3-negative, CCR6-negative, alpha-beta T-lymphocyte - cell - This cell type is compatible with the HIPC Lyoplate markers for 'non-Tc1/Tc17 CD8+ T cell'. Cells of this phenotype may include Tc2 T cells and some naive CD8+ T cells. - CD8-positive, CXCR3-negative, CCR6-negative, alpha-beta T cell - - - - - A CD8-positive, alpha-beta T cell that has the phenotype CXCR3-negative, CCR6-negative. - GOC:add - PMID:22343568 - - - - - non-Tc1/Tc17 CD8+ T cell - PMID:22343568 - + @@ -21106,25 +8481,7 @@ radial glial cells acting as neural progenitors throughout life. - A memory B cell that lacks expression of surface IgD. - IgD- memory B cell - cell - This cell type is compatible with the HIPC Lyoplate markers for 'IgD- memory B cell'. The majority of these cells are class-switched, though some are IgM-positive. - IgD-negative memory B cell - - - - - A memory B cell that lacks expression of surface IgD. - GOC:add - PMID:22343568 - - - - - IgD- memory B cell - PMID:22343568 - + @@ -21132,25 +8489,7 @@ radial glial cells acting as neural progenitors throughout life. - A monocyte that expresses CD14 and is negative for the lineage markers CD3, CD19, and CD20. - monocyte - cell - This cell type is compatible with the HIPC Lyoplate markers for 'monocyte'. Note that while CD14 is considered a reliable marker for human monocytes, it is only expressed on approximately 85% of mouse monocytes. - CD14-positive monocyte - - - - - A monocyte that expresses CD14 and is negative for the lineage markers CD3, CD19, and CD20. - GOC:add - PMID:22343568 - - - - - monocyte - PMID:22343568 - + @@ -21159,19 +8498,7 @@ radial glial cells acting as neural progenitors throughout life. - An intermediate monocyte that is CD14-positive and with low amounts of CD16. - intermediate monocyte, human - cell - Definition is valid for human intermediate monocytes. - CD14-positive, CD16-low monocyte - - - - An intermediate monocyte that is CD14-positive and with low amounts of CD16. - GOC:add - PMID:20628149 - @@ -21179,25 +8506,7 @@ radial glial cells acting as neural progenitors throughout life. - A dendritic cell with the phenotype HLA-DRA-positive. - dendritic cell - cell - This cell type is compatible with the HIPC Lyoplate markers for 'dendritic cell'. The inclusion of HLA-DRA in the definition restricts this definition to human dendritic cells. - dendritic cell, human - - - - - A dendritic cell with the phenotype HLA-DRA-positive. - GOC:add - PMID:22343568 - - - - - dendritic cell - PMID:22343568 - + @@ -21206,25 +8515,7 @@ radial glial cells acting as neural progenitors throughout life. - A myeloid dendritic cell with the phenotype HLA-DRA-positive. - myeloid dendritic cell - cell - This cell type is compatible with the HIPC Lyoplate markers for 'myeloid dendritic cell'. The inclusion of HLA-DRA in the definition restricts this definition to human myeloid dendritic cells. - myeloid dendritic cell, human - - - - - A myeloid dendritic cell with the phenotype HLA-DRA-positive. - GOC:add - PMID:22343568 - - - - - myeloid dendritic cell - PMID:22343568 - + @@ -21233,25 +8524,7 @@ radial glial cells acting as neural progenitors throughout life. - A plasmacytoid dendritic cell with the phenotype HLA-DRA-positive, CD123-positive, and CD11c-negative. - plasmacytoid dendritic cell - cell - This cell type is compatible with the HIPC Lyoplate markers for 'plasmacytoid dendritic cell'. The inclusion of HLA-DRA in the definition restricts this definition to human plasmacytoid dendritic cells. - plasmacytoid dendritic cell, human - - - - - A plasmacytoid dendritic cell with the phenotype HLA-DRA-positive, CD123-positive, and CD11c-negative. - GOC:add - PMID:22343568 - - - - - plasmacytoid dendritic cell - PMID:22343568 - + @@ -21260,74 +8533,7 @@ radial glial cells acting as neural progenitors throughout life. - A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages. These cells are CD34-positive, and express Gata1, Gata2, C/EBPa, and Pu.1. - CMP - common myeloid precursor, CD34-positive - cell - CFU-GEMM - CFU-S - colony forming unit granulocyte, erythrocyte, macrophage, and megakaryocyte - multipotential myeloid stem cell - myeloid stem cell - pluripotent stem cell (bone marrow) - CMP are reportedly CD16-positive, CD32-positive, CD38-positive, CD45RA-negative, CD110-negative, CD117-positive, CD123-positive, and SCA1-negative. - common myeloid progenitor, CD34-positive - - - - - A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages. These cells are CD34-positive, and express Gata1, Gata2, C/EBPa, and Pu.1. - GOC:add - GOC:dsd - GOC:tfm - ISBN:0878932437 - PMCID:PMC2212039 - PMID:10724173 - PMID:16551251 - PMID:16647566 - - - - - CMP - ISBN:0878932437 - - - - - CFU-GEMM - ISBN:0878932437 - - - - - CFU-S - ISBN:0878932437 - - - - - colony forming unit granulocyte, erythrocyte, macrophage, and megakaryocyte - ISBN:0878932437 - - - - - multipotential myeloid stem cell - ISBN:0878932437 - - - - - myeloid stem cell - ISBN:0878932437 - - - - - pluripotent stem cell (bone marrow) - ISBN:0878932437 - + @@ -21335,19 +8541,7 @@ radial glial cells acting as neural progenitors throughout life. - A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities. Cell lacks hematopoeitic lineage markers. - tmeehan - 2010-01-06T03:43:27Z - cell - hematopoietic oligopotent progenitor cell, lineage-negative - - - - A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities. Cell lacks hematopoeitic lineage markers. - GOC:tfm - PMID:19022770 - @@ -21355,22 +8549,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell found in an organism or derived from an organism exhibiting a phenotype that deviates from the expected phenotype of any native cell type of that organism. Abnormal cells are typically found in disease states or disease models. - - 2017-01-30T18:53:32Z - https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C12913 - cell - https://github.com/obophenotype/cell-ontology/issues/448 - abnormal cell - - - - A cell found in an organism or derived from an organism exhibiting a phenotype that deviates from the expected phenotype of any native cell type of that organism. Abnormal cells are typically found in disease states or disease models. - GOC:add - GOC:cg - GOC:wdd - @@ -21378,27 +8557,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD8-positive, alpha beta memory T cell with the phenotype CD45RA-positive, CD45RO-negative, and CCR7-negative. - TEMRA - cell - This cell type is seen human but not found in the mouse. - effector memory CD8-positive, alpha-beta T cell, terminally differentiated - - - - - A CD8-positive, alpha beta memory T cell with the phenotype CD45RA-positive, CD45RO-negative, and CCR7-negative. - GOC:add - GOC:dos - PMID:15032595 - PMID:16237082 - - - - - TEMRA - PMID:16237082 - + @@ -21406,24 +8565,7 @@ radial glial cells acting as neural progenitors throughout life. - An abnormal cell exhibiting dysregulation of cell proliferation or programmed cell death and capable of forming a neoplasm, an aggregate of cells in the form of a tumor mass or an excess number of abnormal cells (liquid tumor) within an organism. - - 2017-01-30T19:16:26Z - https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C12922 - cell - tumor cell - tumour cell - https://github.com/obophenotype/cell-ontology/issues/448 - neoplastic cell - - - - - An abnormal cell exhibiting dysregulation of cell proliferation or programmed cell death and capable of forming a neoplasm, an aggregate of cells in the form of a tumor mass or an excess number of abnormal cells (liquid tumor) within an organism. - GOC:add - GOC:cg - GOC:wdd - + @@ -21431,23 +8573,7 @@ radial glial cells acting as neural progenitors throughout life. - A neoplastic cell that is capable of entering a surrounding tissue - - 2017-01-30T19:39:12Z - https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C12917 - cell - cancer cell - https://github.com/obophenotype/cell-ontology/issues/448 - malignant cell - - - - - A neoplastic cell that is capable of entering a surrounding tissue - GOC:add - GOC:cg - GOC:wdd - + @@ -21455,21 +8581,7 @@ radial glial cells acting as neural progenitors throughout life. - A lymphocyte that lacks characteristic T cell, B cell, myeloid cell, and dendritic cell markers, that functions as part of the innate immune response to produce cytokines and other effector responses. - - 2017-01-30T20:20:48Z - cell - innate lymphoid cell - - - - A lymphocyte that lacks characteristic T cell, B cell, myeloid cell, and dendritic cell markers, that functions as part of the innate immune response to produce cytokines and other effector responses. - GOC:add - GOC:dsd - PMID:23292121 - PMID:23348417 - @@ -21477,24 +8589,7 @@ radial glial cells acting as neural progenitors throughout life. - A progenitor cell committed to the erythroid lineage. This cell is ter119-positive but lacks expression of other hematopoietic lineage markers (lin-negative). - BTO:0004911 - cell - BFU-E - CFU-E - blast forming unit erythroid - burst forming unit erythroid - colony forming unit erythroid - erythroid stem cell - erythroid progenitor cell, mammalian - - - - - A progenitor cell committed to the erythroid lineage. This cell is ter119-positive but lacks expression of other hematopoietic lineage markers (lin-negative). - GOC:add - ISBN:0721601464 - + @@ -21502,20 +8597,7 @@ radial glial cells acting as neural progenitors throughout life. - An innate lymphoid cell that is capable of producing the type 1 cytokine IFN-gamma, but not Th2 or Th17 cell-associated cytokines. - - 2017-01-30T20:42:44Z - cell - group 1 innate lymphoid cell - - - - An innate lymphoid cell that is capable of producing the type 1 cytokine IFN-gamma, but not Th2 or Th17 cell-associated cytokines. - GOC:add - GOC:dsd - PMID:23348417 - @@ -21523,21 +8605,7 @@ radial glial cells acting as neural progenitors throughout life. - A group 1 innate lymphoid cell that is non-cytotoxic. - - 2017-01-30T20:54:12Z - cell - ILC1 - - - - A group 1 innate lymphoid cell that is non-cytotoxic. - GOC:add - GOC:dsd - PMID:23292121 - PMID:23348417 - @@ -21545,23 +8613,7 @@ radial glial cells acting as neural progenitors throughout life. - An innate lymphoid cell that is capable of producing T-helper 2-cell associated cytokines upon stimulation. - - 2017-01-30T21:20:08Z - ILC2 - nuocyte - cell - group 2 innate lymphoid cell - - - - - An innate lymphoid cell that is capable of producing T-helper 2-cell associated cytokines upon stimulation. - GOC:add - GOC:dsd - PMID:23292121 - PMID:23562755 - + @@ -21569,26 +8621,7 @@ radial glial cells acting as neural progenitors throughout life. - A fat cell that is beige in color, thermogenic, and which differentiates in white fat tissue from a Myf5-negative progenitor. - beige brown adipocyte - beige fat cell - beige/brite adipocyte - brite adipocyte - brite cell - brite fat cell - cell - beige adipocyte - - - - - A fat cell that is beige in color, thermogenic, and which differentiates in white fat tissue from a Myf5-negative progenitor. - GOC:add - GOC:cvs - GOC:ymb - PMID:22796012 - PMID:25851693 - + @@ -21596,22 +8629,7 @@ radial glial cells acting as neural progenitors throughout life. - An innate lymphoid cell that constituitively expresses RORgt and is capable of expressing IL17A and/or IL-22. - - 2017-01-31T20:21:26Z - ILC3 - cell - group 3 innate lymphoid cell - - - - An innate lymphoid cell that constituitively expresses RORgt and is capable of expressing IL17A and/or IL-22. - GOC:add - GOC:dsd - PMID:23292121 - PMID:23348417 - @@ -21620,9 +8638,6 @@ radial glial cells acting as neural progenitors throughout life. - FBbt:00004230 - cell - visual pigment cell (sensu Nematoda and Protostomia) @@ -21631,23 +8646,7 @@ radial glial cells acting as neural progenitors throughout life. - An erythroid progenitor cell is Kit-positive, Ly6A-negative, CD41-negative, CD127-negative, and CD123-negative. This cell type is also described as being lin-negative, Kit-positive, CD150-negative, CD41-negative, CD105-positive, and FcgR-negative. - tmeehan - 2010-04-26T10:14:16Z - c- Kit-positive erythroid progenitor cell - cell - Markers found on mouse cells. - Kit-positive erythroid progenitor cell - - - - - An erythroid progenitor cell is Kit-positive, Ly6A-negative, CD41-negative, CD127-negative, and CD123-negative. This cell type is also described as being lin-negative, Kit-positive, CD150-negative, CD41-negative, CD105-positive, and FcgR-negative. - GOC:ak - GOC:tfm - PMID:19805084 - http://www.immgen.org/index_content.html - + @@ -21655,21 +8654,7 @@ radial glial cells acting as neural progenitors throughout life. - A granulocyte monocyte progenitor is CD34-positive, CD38-positive, IL-3receptor-alpha-positive and is CD45RA-negative. - tmeehan - 2010-01-13T03:19:22Z - cell - Markers are for human cells. According to different research groups, CD45RA is present or absent on this cell population. - CD34-positive, CD38-positive granulocyte monocyte progenitor - - - - A granulocyte monocyte progenitor is CD34-positive, CD38-positive, IL-3receptor-alpha-positive and is CD45RA-negative. - GOC:tfm - PMID:12615892 - PMID:19022770 - @@ -21677,24 +8662,7 @@ radial glial cells acting as neural progenitors throughout life. - A granulocyte monocyte progenitor that is Kit-positive, CD34-positive, Fc-gamma receptor II/II-positive, and is Sca-1-negative, Il7ra-negative, Cxc3r1-negative, and CD90-negative. - tmeehan - 2010-01-13T03:19:28Z - cell - Markers are found on mouse cells. - Kit-positive granulocyte monocyte progenitor - - - - - A granulocyte monocyte progenitor that is Kit-positive, CD34-positive, Fc-gamma receptor II/II-positive, and is Sca-1-negative, Il7ra-negative, Cxc3r1-negative, and CD90-negative. - GOC:tfm - PMID:12615892 - PMID:16322423 - PMID:19022770 - PMID:19273628 - http://www.immgen.org/index_content.html - + @@ -21702,22 +8670,7 @@ radial glial cells acting as neural progenitors throughout life. - An erythroid progenitor cell that is CD34-positive and is GlyA-negative. - tmeehan - 2010-04-26T10:14:30Z - FMA:83517 - cell - Cell markers associated with human cells. - CD34-positive, GlyA-negative erythroid progenitor cell - - - - An erythroid progenitor cell that is CD34-positive and is GlyA-negative. - GOC:ak - GOC:tfm - PMID:19621348 - @@ -21725,21 +8678,7 @@ radial glial cells acting as neural progenitors throughout life. - A proerythoblast that is CD34-negative and GlyA-negative. - tmeehan - 2010-04-26T10:31:50Z - cell - Cell surface markers are associated with human cells. - CD34-negative, GlyA-negative proerythroblast - - - - A proerythoblast that is CD34-negative and GlyA-negative. - GOC:ak - GOC:tfm - PMID:19621348 - @@ -21747,21 +8686,7 @@ radial glial cells acting as neural progenitors throughout life. - A megakaryocyte erythroid progenitor cell is CD34-positive, CD38-positive and is IL3-receptor alpha-negative and CD45RA-negative. - tmeehan - 2010-01-13T03:43:10Z - cell - Markers are associated with human cell type. - CD34-positive, CD38-positive megakaryocyte erythroid progenitor cell - - - - A megakaryocyte erythroid progenitor cell is CD34-positive, CD38-positive and is IL3-receptor alpha-negative and CD45RA-negative. - GOC:tfm - PMID:12615892 - PMID:190227700 - @@ -21769,22 +8694,7 @@ radial glial cells acting as neural progenitors throughout life. - A megakaryocyte erythroid progenitor cell that is Kit-positive and is Sca1-negative, CD34-negative, CD90-negative, IL7r-alpha-negative and Fcgr II/III-low. - tmeehan - 2010-01-13T03:43:12Z - cell - Markers are associated with mouse cells. - Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell - - - - A megakaryocyte erythroid progenitor cell that is Kit-positive and is Sca1-negative, CD34-negative, CD90-negative, IL7r-alpha-negative and Fcgr II/III-low. - GOC:tfm - PMID:12615892 - PMID:19022770 - http://www.immgen.org/index_content.html - @@ -21792,20 +8702,7 @@ radial glial cells acting as neural progenitors throughout life. - A lineage marker-negative, CD34-positive, IL5r-alpha-positive, and Sca1-negative eosinophil progenitor cell. - tmeehan - 2010-01-14T03:25:15Z - cell - Markers are found on mouse cells. - Kit-low, CD34-positive eosinophil progenitor cell - - - - A lineage marker-negative, CD34-positive, IL5r-alpha-positive, and Sca1-negative eosinophil progenitor cell. - GOC:tfm - PMID:17582345 - @@ -21813,20 +8710,7 @@ radial glial cells acting as neural progenitors throughout life. - A lineage marker-negative, CD34-positive, CD38-positive, IL3r-alpha-positive, IL5r-alpha-positive, and CD45RA-negative eosinophil progenitor cell. - tmeehan - 2010-01-14T03:25:17Z - cell - Markers are associated with human cells. - CD34-positive, CD38-positive eosinophil progenitor cell - - - - A lineage marker-negative, CD34-positive, CD38-positive, IL3r-alpha-positive, IL5r-alpha-positive, and CD45RA-negative eosinophil progenitor cell. - GOC:tfm - PMCID:PMC2626675 - @@ -21836,20 +8720,7 @@ radial glial cells acting as neural progenitors throughout life. - A progenitor cell that can give rise to plasmacytoid and myeloid dendritic cells, and to monocytes and macrophages. - tmeehan - 2010-01-19T02:51:58Z - MDP - cell - macrophage dendritic cell progenitor - - - - A progenitor cell that can give rise to plasmacytoid and myeloid dendritic cells, and to monocytes and macrophages. - GOC:tfm - PMID:19273628 - @@ -21858,18 +8729,7 @@ radial glial cells acting as neural progenitors throughout life. - A lin-negative, MHC-II-negative, CD11c-positive, FLT3-positive cell with intermediate expression of SIRP-alpha. - tmeehan - 2010-01-19T03:39:30Z - cell - pre-conventional dendritic cell - - - - A lin-negative, MHC-II-negative, CD11c-positive, FLT3-positive cell with intermediate expression of SIRP-alpha. - GOC:tfm - @@ -21877,21 +8737,7 @@ radial glial cells acting as neural progenitors throughout life. - A progenitor cell that can give rise to plasmacytoid and myeloid dendritic cells, and to monocytes and macrophages. Marker for this cell is Kit-high, CD115-positive, CD135-positive, Cx3cr1-positive, and is Il7ra-negative. - tmeehan - 2010-01-26T02:43:40Z - murine MDP - cell - Markers are associated with mouse cells. - Kit-positive macrophage dendritic cell progenitor - - - - A progenitor cell that can give rise to plasmacytoid and myeloid dendritic cells, and to monocytes and macrophages. Marker for this cell is Kit-high, CD115-positive, CD135-positive, Cx3cr1-positive, and is Il7ra-negative. - GOC:tfm - PMID:19273628 - @@ -21899,21 +8745,7 @@ radial glial cells acting as neural progenitors throughout life. - A proerythoblast that is Kit-low, Lyg76-positive, and CD71-positive. - tmeehan - 2010-04-26T10:31:56Z - cell - Markers are associated with mouse cells. - Kit-low proerythroblast - - - - A proerythoblast that is Kit-low, Lyg76-positive, and CD71-positive. - GOC:ak - GOC:tfm - PMID:19805084 - @@ -21921,21 +8753,7 @@ radial glial cells acting as neural progenitors throughout life. - A basophilic erythroblast that is GlyA-positive. - tmeehan - 2010-04-26T10:41:15Z - cell - Markers are associated with human cells. - GlyA-positive basophillic erythroblast - - - - A basophilic erythroblast that is GlyA-positive. - GOC:ak - GOC:tfm - PMID:1638021 - @@ -21943,21 +8761,7 @@ radial glial cells acting as neural progenitors throughout life. - A basophilic erythroblast that is Lyg 76-high and is Kit-negative. - tmeehan - 2010-04-26T10:41:22Z - cell - Cell surface markers are associated with mouse cells. - Kit-negative, Ly-76 high basophilic erythroblast - - - - A basophilic erythroblast that is Lyg 76-high and is Kit-negative. - GOC:ak - GOC:tfm - PMID:19805084 - @@ -21965,21 +8769,7 @@ radial glial cells acting as neural progenitors throughout life. - A polychromatophilic erythroblast that is Lyg 76-high and is Kit-negative. - tmeehan - 2010-04-26T10:53:11Z - late basophilic and polychromatophilic erythroblast - cell - Kit-negative, Ly-76 high polychromatophilic erythroblast - - - - A polychromatophilic erythroblast that is Lyg 76-high and is Kit-negative. - GOC:ak - GOC:tfm - PMID:19805084 - @@ -21987,21 +8777,7 @@ radial glial cells acting as neural progenitors throughout life. - A polychromatiic erythroblast that is Gly-A-positive and CD71-low. - tmeehan - 2010-04-26T10:53:16Z - cell - Cell surface markers are associated with human cells. - CD71-low, GlyA-positive polychromatic erythroblast - - - - A polychromatiic erythroblast that is Gly-A-positive and CD71-low. - GOC:ak - GOC:tfm - PMID:1638021 - @@ -22009,21 +8785,7 @@ radial glial cells acting as neural progenitors throughout life. - An orthochromatophilic erythroblast that is ter119-high, CD71-low, and Kit-negative. - tmeehan - 2010-04-26T11:04:15Z - cell - Cell surface markers associated with mouse cells. - Kit-negative, Ly-76 high orthochromatophilic erythroblasts - - - - An orthochromatophilic erythroblast that is ter119-high, CD71-low, and Kit-negative. - GOC:ak - GOC:tfm - PMID:19805084 - @@ -22031,21 +8793,7 @@ radial glial cells acting as neural progenitors throughout life. - An erythroblast that is GlyA-positive and CD71-negative. - tmeehan - 2010-04-26T11:04:21Z - cell - Markers associated with human cells. - CD71-negative, GlyA-positive orthochromatic erythroblast - - - - An erythroblast that is GlyA-positive and CD71-negative. - GOC:ak - GOC:tfm - PMID:1638021 - @@ -22053,21 +8801,7 @@ radial glial cells acting as neural progenitors throughout life. - A reticulocyte that is Ly76-high and is Kit-negative. - tmeehan - 2010-04-26T11:37:00Z - cell - Marker associated with mouse cells. - Ly-76 high reticulocyte - - - - A reticulocyte that is Ly76-high and is Kit-negative. - GOC:ak - GOC:tfm - PMID:18539294 - @@ -22075,21 +8809,7 @@ radial glial cells acting as neural progenitors throughout life. - A reticulocyte that is GlyA-positive. - tmeehan - 2010-04-26T11:48:25Z - cell - Markers is associated with human cells. - GlyA-positive reticulocytes - - - - A reticulocyte that is GlyA-positive. - GOC:ak - GOC:tfm - PMID:1638021 - @@ -22097,21 +8817,7 @@ radial glial cells acting as neural progenitors throughout life. - An enucleate erythrocyte that is GlyA-positive. - tmeehan - 2010-04-26T11:51:22Z - cell - Marker is associated with human cell types. - GlyA-positive erythrocyte - - - - An enucleate erythrocyte that is GlyA-positive. - GOC:ak - GOC:tfm - PMID:20134094 - @@ -22119,21 +8825,7 @@ radial glial cells acting as neural progenitors throughout life. - An enucleate erythrocyte that is Lyg-76-high. - tmeehan - 2010-04-26T11:51:27Z - cell - Marker is associated with mouse cell types. - Ly-76 high positive erythrocyte - - - - An enucleate erythrocyte that is Lyg-76-high. - GOC:ak - GOC:tfm - PMID:19805084 - @@ -22141,21 +8833,7 @@ radial glial cells acting as neural progenitors throughout life. - A megakaroycotye progenitor cell that is CD34-positive, CD41-positive and CD42-positive on the cell surface. - tmeehan - 2010-04-26T02:39:09Z - cell - Markers are associated with human cell type. - CD34-positive, CD41-positive, CD42-positive megakaryocyte progenitor cell - - - - A megakaroycotye progenitor cell that is CD34-positive, CD41-positive and CD42-positive on the cell surface. - GOC:ak - GOC:tfm - PMID:15232614 - @@ -22163,21 +8841,7 @@ radial glial cells acting as neural progenitors throughout life. - A megakaryocyte progenitor cell that is Kit-positive, CD41-positive, CD9-positive, Sca-1-negative, IL7ralpha-negative, CD150-negative, and Fcgamma receptor II/III-low. - tmeehan - 2010-04-26T02:39:15Z - cell - Markers are associated with mouse cells. - Kit-positive megakaryocyte progenitor cell - - - - A megakaryocyte progenitor cell that is Kit-positive, CD41-positive, CD9-positive, Sca-1-negative, IL7ralpha-negative, CD150-negative, and Fcgamma receptor II/III-low. - GOC:ak - GOC:tfm - PMID:16951553 - @@ -22185,21 +8849,7 @@ radial glial cells acting as neural progenitors throughout life. - A megakaryocyte progenitor cell that is CD34-positive, CD41-positive, and CD42-negative. - tmeehan - 2010-04-26T03:52:47Z - cell - Markers are commonly associated with human cells. - CD34-positive, CD41-positive, CD42-negative megakaryocyte progenitor cell - - - - A megakaryocyte progenitor cell that is CD34-positive, CD41-positive, and CD42-negative. - GOC:ak - GOC:tfm - PMID:15232614 - @@ -22207,21 +8857,7 @@ radial glial cells acting as neural progenitors throughout life. - A megakaryocyte progenitor cell that is CD34-negative, CD41-positive and CD42-positive. - tmeehan - 2010-04-26T03:59:22Z - cell - Markers are commonly associated with human cells. - CD34-negative, CD41-positive, CD42-positive megakaryocyte cell - - - - A megakaryocyte progenitor cell that is CD34-negative, CD41-positive and CD42-positive. - GOC:ak - GOC:tfm - PMID:15232614 - @@ -22229,19 +8865,7 @@ radial glial cells acting as neural progenitors throughout life. - A megakaryocyte cell with is CD9-positive and CD41-positive. - tmeehan - 2010-04-27T10:39:07Z - cell - Markers are commonly associated with mouse cells. - CD9-positive, CD41-positive megakaryocyte cell - - - - A megakaryocyte cell with is CD9-positive and CD41-positive. - GOC:tfm - @@ -22250,23 +8874,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell type that can give rise to basophil and mast cells. This cell is CD34-positive, CD117-positive, CD125-positive, FceRIa-negative, and T1/ST2-negative, and expresses Gata-1, Gata-2, C/EBPa - tmeehan - 2010-04-27T12:46:33Z - BMCP - cell - There may be an intermediate cell type. These cells also CD13-positive, CD16-positive, CD32-positive, and integrin beta 7-positive. Transcription factors: GATA1-positive, MCP-1-positive, mitf-positive, PU.1-positive, and CEBP/a-low. - basophil mast progenitor cell - - - - - A cell type that can give rise to basophil and mast cells. This cell is CD34-positive, CD117-positive, CD125-positive, FceRIa-negative, and T1/ST2-negative, and expresses Gata-1, Gata-2, C/EBPa - GOC:ak - GOC:dsd - GOC:tfm - PMCID:PMC1312421 - + @@ -22274,19 +8882,7 @@ radial glial cells acting as neural progenitors throughout life. - A lineage-negative, Kit-positive, CD45-positive mast cell progenitor that is Fc-epsilon RIalpha-low. - tmeehan - 2010-04-27T01:22:19Z - cell - Fc-epsilon RIalpha-low mast cell progenitor - - - - A lineage-negative, Kit-positive, CD45-positive mast cell progenitor that is Fc-epsilon RIalpha-low. - GOC:tfm - PMCID:PMC1312421 - @@ -22294,20 +8890,7 @@ radial glial cells acting as neural progenitors throughout life. - A lineage negative, Sca1-negative basophil progenitor cell that is Fc epsilon RIalpha-high. - tmeehan - 2010-04-27T01:22:32Z - cell - Markers are associated with mouse cells. - Fc-epsilon RIalpha-high basophil progenitor cell - - - - A lineage negative, Sca1-negative basophil progenitor cell that is Fc epsilon RIalpha-high. - GOC:tfm - PMCID:PMC1312421 - @@ -22315,19 +8898,8 @@ radial glial cells acting as neural progenitors throughout life. - A hematopoietic progenitor cell that is capable of developing into only one lineage of hematopoietic cells. - tmeehan - 2010-01-06T03:43:20Z - cell - hematopoietic lineage restricted progenitor cell + - - - - A hematopoietic progenitor cell that is capable of developing into only one lineage of hematopoietic cells. - GOC:tfm - PMID:19022770 - @@ -22335,20 +8907,7 @@ radial glial cells acting as neural progenitors throughout life. - A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities. Cell lacks hematopoeitic lineage markers. - tmeehan - 2010-01-06T03:43:27Z - cell - This cell type is intended to be compatible with any vertebrate hematopoietic oligopotent progenitor cell. For mammalian hematopoietic oligopotent progenitor cells known to be lineage-negative, please use the term 'hematopoietic oligopotent progenitor cell' (CL_0001060). - hematopoietic oligopotent progenitor cell - - - - A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities. Cell lacks hematopoeitic lineage markers. - GOC:tfm - PMID:19022770 - @@ -22356,23 +8915,7 @@ radial glial cells acting as neural progenitors throughout life. - A hematopoietic stem cell capable of rapid replenishment of myeloerythroid progenitors and limited self renewal capability. This cell is Kit-positive, Sca1-positive, CD34-positive, CD150-positive, and is Flt3-negative. - tmeehan - 2010-01-08T09:19:25Z - ST stem cell - ST-HSC - cell - Markers are associated with mouse cells. These cells are also reportedly CD11b-low and CD90-low. - short term hematopoietic stem cell - - - - - A hematopoietic stem cell capable of rapid replenishment of myeloerythroid progenitors and limited self renewal capability. This cell is Kit-positive, Sca1-positive, CD34-positive, CD150-positive, and is Flt3-negative. - GOC:tfm - PMID:15572596 - PMID:19022770 - + @@ -22380,23 +8923,7 @@ radial glial cells acting as neural progenitors throughout life. - A hematopoietic stem cell with long term self renewal capability. This cell is Kit-positive, Sca1-positive, CD150-positive, CD90-low, CD34-negative and Flt3-negative. - tmeehan - 2010-01-08T09:19:28Z - LT stem cell - LT-HSC - cell - Markers are associated with mouse cells. - long term hematopoietic stem cell - - - - - A hematopoietic stem cell with long term self renewal capability. This cell is Kit-positive, Sca1-positive, CD150-positive, CD90-low, CD34-negative and Flt3-negative. - GOC:tfm - PMID:15572596 - PMID:17582345 - + @@ -22404,20 +8931,7 @@ radial glial cells acting as neural progenitors throughout life. - A hematopoietic progenitor that has restricted self-renewal capability. Cell is Kit-positive, Ly6-positive, CD150-negative and Flt3-negative. - tmeehan - 2010-01-08T11:16:33Z - cell - Markers are associated with mouse cells. - Slamf1-negative multipotent progenitor cell - - - - A hematopoietic progenitor that has restricted self-renewal capability. Cell is Kit-positive, Ly6-positive, CD150-negative and Flt3-negative. - GOC:tfm - PMID:19022770 - @@ -22425,21 +8939,8 @@ radial glial cells acting as neural progenitors throughout life. - A hematopoietic progenitor that has some limited self-renewal capability. Cells are lin-negative, Kit-positive, CD34-positive, and Slamf1-positive. - tmeehan - 2010-01-08T11:16:35Z - KSL cell - cell - Markers are associated with mouse cells. - Slamf1-positive multipotent progenitor cell + - - - - A hematopoietic progenitor that has some limited self-renewal capability. Cells are lin-negative, Kit-positive, CD34-positive, and Slamf1-positive. - GOC:tfm - PMID:19022770 - @@ -22447,26 +8948,7 @@ radial glial cells acting as neural progenitors throughout life. - Intraepithelial T cells with a memory phenotype of CD2-positive, CD5-positive, and CD44-positive. - tmeehan - 2009-10-20T02:20:43Z - memory alpha beta IEL - cell - CD2-positive, CD5-positive, CD44-positive alpha-beta intraepithelial T cell - - - - - Intraepithelial T cells with a memory phenotype of CD2-positive, CD5-positive, and CD44-positive. - GOC:tfm - PMID:16048545 - - - - - memory alpha beta IEL - PMID:16048545 - + @@ -22474,73 +8956,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD4-positive, CXCR5-positive, CCR7-negative alpha-beta T cell located in follicles of secondary lymph nodes that expresses is BCL6-high, ICOS-high and PD1-high, and stimulates follicular B cells to undergo class-switching and antibody production. - tmeehan - 2009-10-29T04:01:27Z - T(FH) - Tfh - cell - follicular B helper T cell - follicular T cell - follicular T-cell - follicular T-helper cell - follicular helper T cell - follicular helper T-cell - T follicular helper cell - - - - - A CD4-positive, CXCR5-positive, CCR7-negative alpha-beta T cell located in follicles of secondary lymph nodes that expresses is BCL6-high, ICOS-high and PD1-high, and stimulates follicular B cells to undergo class-switching and antibody production. - GOC:tfm - PMID:19855402 - PMID:20107805 - PMID:22043829 - - - - - T(FH) - PMID:20207847 - - - - - Tfh - PMID:20107805 - PMID:20383172 - - - - - follicular B helper T cell - PMID:22043829 - - - - - follicular T cell - PMID:20107805 - PMID:21914188 - - - - - follicular T-helper cell - PMID:22552227 - - - - - follicular helper T cell - PMID:22649468 - - - - - follicular helper T-cell - PMID:22508770 - + @@ -22548,19 +8964,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD24-high, CD4-low, CD8-low, CD44-negative, NK1.1-negative NK T cell. - tmeehan - 2009-10-29T04:09:16Z - cell - immature NK T cell stage I - - - - A CD24-high, CD4-low, CD8-low, CD44-negative, NK1.1-negative NK T cell. - GOC:tfm - PMID:17589542 - @@ -22568,22 +8972,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD24-low, CD44-negative, NK1.1-negative NK T cell. - tmeehan - 2009-10-29T04:13:43Z - NKT.44-NK1.1-.Th - cell - NKT.44-NK1.1-.Th was assigned as an exact synonym based on sorting strategy displayed at immgene.org. - immature NK T cell stage II - - - - A CD24-low, CD44-negative, NK1.1-negative NK T cell. - GOC:tfm - PMID:17589542 - http://www.immgen.org/index_content.html - @@ -22591,19 +8980,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD24-low, CD44-positive, DX5-low, NK1.1-negative NK T cell. - tmeehan - 2009-10-29T04:14:48Z - NKT.44+.NK1.1-.Th - cell - immature NK T cell stage III - - - - A CD24-low, CD44-positive, DX5-low, NK1.1-negative NK T cell. - PMID:17589542 - @@ -22611,21 +8988,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD24-low, CD44-positive, DX5-high, NK1.1-negative NK T cell. - tmeehan - 2009-10-29T04:17:38Z - NKT.44+.NK1.1-.Th - cell - immature NK T cell stage IV - - - - A CD24-low, CD44-positive, DX5-high, NK1.1-negative NK T cell. - GOC:tfm - PMID:17589542 - http://www.immgen.org/index_content.html - @@ -22633,21 +8996,7 @@ radial glial cells acting as neural progenitors throughout life. - A hematopoietic multipotent progenitor cell that is CD34-positive, CD38-negative, CD45RA-negative, and CD90-negative. - tmeehan - 2010-01-12T11:14:15Z - cell - Cell markers are associated with human hematopoietic multipotent progenitor cells. - CD34-positive, CD38-negative multipotent progenitor cell - - - - A hematopoietic multipotent progenitor cell that is CD34-positive, CD38-negative, CD45RA-negative, and CD90-negative. - GOC:tfm - PMID:18371405 - PMID:19022770 - @@ -22655,20 +9004,7 @@ radial glial cells acting as neural progenitors throughout life. - A basophil mast progenitor cell that is Beta-7 integrin-high, Kit-positive FcRgammaII/III-positive and Sca1-negative. - tmeehan - 2010-04-27T01:22:38Z - cell - Markers are associated with mouse cells. - Kit-positive, integrin beta7-high basophil mast progenitor cell - - - - A basophil mast progenitor cell that is Beta-7 integrin-high, Kit-positive FcRgammaII/III-positive and Sca1-negative. - GOC:ak - GOC:tfm - @@ -22676,25 +9012,7 @@ radial glial cells acting as neural progenitors throughout life. - A pro-B cell that CD45R/B220-positive, CD43-positive, HSA-low, BP-1-negative and Ly6c-negative. This cell type is also described as being lin-negative, AA4-positive, Kit-positive, IL7Ra-positive and CD45R-positive. - tmeehan - 2010-04-28T10:50:07Z - fraction A - cell - pre pro B cell - Markers associated with mouse cells. - Fraction A pre-pro B cell - - - - - A pro-B cell that CD45R/B220-positive, CD43-positive, HSA-low, BP-1-negative and Ly6c-negative. This cell type is also described as being lin-negative, AA4-positive, Kit-positive, IL7Ra-positive and CD45R-positive. - GOC:ak - GOC:tfm - PMID:12633665 - PMID:17582343 - http://www.immgen.org/index_content.html - + @@ -22702,21 +9020,7 @@ radial glial cells acting as neural progenitors throughout life. - A pro-B cell that is CD22-positive, CD34-positive, CD38-positive and TdT-positive (has TdT activity). Pre-BCR is expressed on the cell surface. Cell is CD19-negative, CD20-negative, complement receptor type 2-negative and CD10-low. D-to-J recombination of the heavy chain occurs at this stage. - tmeehan - 2010-04-28T11:19:11Z - cell - Markers are commonly associated with human cells. These cells are also reportedly CD21-negative. Transcription factors: PU.1-positive, Ikaros-positive, E2A-positive, and PAX5-positive. - early pro-B cell - - - - A pro-B cell that is CD22-positive, CD34-positive, CD38-positive and TdT-positive (has TdT activity). Pre-BCR is expressed on the cell surface. Cell is CD19-negative, CD20-negative, complement receptor type 2-negative and CD10-low. D-to-J recombination of the heavy chain occurs at this stage. - GOC:dsd - GOC:tfm - PMID:18432934 - @@ -22724,23 +9028,7 @@ radial glial cells acting as neural progenitors throughout life. - A precursor B cell that is CD45RA-positive, CD43-positive, CD24-positive and BP-1-negative. - tmeehan - 2010-04-28T11:56:21Z - Fr. B - Fraction B - cell - Markers are commonly associated with mouse cells. These cells are also reportedly RAG1-positive and RAG2-positive. - Fraction B precursor B cell - - - - - A precursor B cell that is CD45RA-positive, CD43-positive, CD24-positive and BP-1-negative. - GOC:ak - GOC:tfm - PMID:18432934 - + @@ -22748,21 +9036,7 @@ radial glial cells acting as neural progenitors throughout life. - A pre-B cell precursor is CD19-low, CD22-positive , CD34-positive, CD38-positive. - tmeehan - 2010-04-28T12:06:06Z - cell - Late pro-B cells are also reportedly CD10-positive, CD20-negative, CD21-negative, and TdT-positive. Transcription factors: PU.1-positive, Ikaros-positive, E2A-positive, and PAX5-positive. - late pro-B cell - - - - A pre-B cell precursor is CD19-low, CD22-positive , CD34-positive, CD38-positive. - GOC:dsd - GOC:tfm - PMID:18432934 - @@ -22770,20 +9044,7 @@ radial glial cells acting as neural progenitors throughout life. - A precursor B cell is CD45R-positive, CD43-positive, CD24-positive, and BP-positive. Intracellularly expression of surrogate light chain, Rag1 and Rag2, TdT, occurs while there is no expression of mu heavy chain. - tmeehan - 2010-04-28T02:04:01Z - cell - Fraction C - Fraction C precursor B cell - - - - A precursor B cell is CD45R-positive, CD43-positive, CD24-positive, and BP-positive. Intracellularly expression of surrogate light chain, Rag1 and Rag2, TdT, occurs while there is no expression of mu heavy chain. - GOC:tfm - PMID:17582343 - @@ -22791,21 +9052,7 @@ radial glial cells acting as neural progenitors throughout life. - A pre-BCR-positive precursor B cell that is CD24-high, CD25-positive, CD43-positive, CD45R-positive and BP-positive. - tmeehan - 2010-04-28T02:13:46Z - Fr. C' - Fraction C-prime - cell - Fraction C' precursor B cell - - - - A pre-BCR-positive precursor B cell that is CD24-high, CD25-positive, CD43-positive, CD45R-positive and BP-positive. - GOC:tfm - PMID:17582343 - @@ -22813,21 +9060,7 @@ radial glial cells acting as neural progenitors throughout life. - A pre-BCR positive T cell that is CD38-high. - tmeehan - 2010-04-28T02:27:47Z - cell - large pre-B cell type I - Markers are associated with human cells. - CD38-high pre-BCR positive cell - - - - A pre-BCR positive T cell that is CD38-high. - GOC:tfm - PMID:18432934 - @@ -22835,32 +9068,7 @@ radial glial cells acting as neural progenitors throughout life. - A pre-B cell that is pre-BCR-negative, and the kappa- and lambda- light immunoglobulin light chain-negative, CD43-low, and is BP-1-positive, CD45R-positive and CD25-positive. This cell type is also described as being AA4-positive, IgM-negative, CD19-positive, CD43-low/negative, and HSA-positive. - tmeehan - 2010-04-28T02:55:16Z - Fr. D - Fraction D pre-B cell - cell - Fraction D precursor B cells are also reportedly CD24-positive and sIgD-negative. - Fraction D precursor B cell - - - - - A pre-B cell that is pre-BCR-negative, and the kappa- and lambda- light immunoglobulin light chain-negative, CD43-low, and is BP-1-positive, CD45R-positive and CD25-positive. This cell type is also described as being AA4-positive, IgM-negative, CD19-positive, CD43-low/negative, and HSA-positive. - GOC:ak - GOC:dsd - GOC:tfm - PMID:17582343 - PMID:18432934 - http://www.immgen.org/index_content.html - - - - - Fraction D pre-B cell - GOC:tfm - + @@ -22868,21 +9076,7 @@ radial glial cells acting as neural progenitors throughout life. - A small pre-B cell that is CD22-positive and CD38-low. - tmeehan - 2010-04-28T03:04:48Z - small pre-B cell - cell - Markers are associated with human cell. RAG expression maybe diminishing. - CD22-positive, CD38-low small pre-B cell - - - - A small pre-B cell that is CD22-positive and CD38-low. - GOC:tfm - PMID:18432934 - @@ -22890,23 +9084,7 @@ radial glial cells acting as neural progenitors throughout life. - An immature B cell that is IgM-positive, CD45R-positive, CD43-low, CD25-negative, and CD127-negative. This cell type has also been described as being AA4-positive, IgM-positive, CD19-positive, CD43-low/negative, and HSA-positive. - tmeehan - 2010-04-28T03:13:47Z - cell - Markers associated with mouse cells. These cells are also reportedly sIgD-negative. - Fraction E immature B cell - - - - - An immature B cell that is IgM-positive, CD45R-positive, CD43-low, CD25-negative, and CD127-negative. This cell type has also been described as being AA4-positive, IgM-positive, CD19-positive, CD43-low/negative, and HSA-positive. - GOC:ak - GOC:dsd - GOC:tfm - PMID:17582343 - PMID:18432934 - + @@ -22914,20 +9092,7 @@ radial glial cells acting as neural progenitors throughout life. - An immature B cell that is CD38-negative, CD10-low, CD21-low, and CD22-high. - tmeehan - 2010-04-28T03:19:14Z - cell - Markers are associated with human cell type. - CD38-negative immature B cell - - - - An immature B cell that is CD38-negative, CD10-low, CD21-low, and CD22-high. - GOC:tfm - PMID:18432934 - @@ -22935,19 +9100,7 @@ radial glial cells acting as neural progenitors throughout life. - A mature B cell subset originally defined as having being CD45R-positive, IgM-positive, IgD-positive and CD43-negative. Subsequent research demonstrated being CD21-positive and CD23-negative and CD93 negative. - tmeehan - 2010-04-30T03:01:48Z - cell - Fraction F mature B cell - - - - A mature B cell subset originally defined as having being CD45R-positive, IgM-positive, IgD-positive and CD43-negative. Subsequent research demonstrated being CD21-positive and CD23-negative and CD93 negative. - GOC:tfm - PMID:17582343 - @@ -22956,32 +9109,7 @@ radial glial cells acting as neural progenitors throughout life. - A classical monocyte that is CD14-positive, CD16-negative, CD64-positive, CD163-positive. - tmeehan - 2010-06-05T08:25:41Z - CD16- monocyte - CD16-negative monocyte - cell - This cell type is compatible with the HIPC Lyoplate markers for 'CD16- monocyte'. The markers used in the definition are associated with human monocytes. - CD14-positive, CD16-negative classical monocyte - - - - - A classical monocyte that is CD14-positive, CD16-negative, CD64-positive, CD163-positive. - GOC:add - GOC:tfm - PMID:15615263 - PMID:1706877 - PMID:19689341 - PMID:22343568 - - - - - CD16- monocyte - PMID:22343568 - + @@ -22990,20 +9118,7 @@ radial glial cells acting as neural progenitors throughout life. - A resident monocyte that is Gr-1 low, CD43-positive, and CX3CR1-positive. - tmeehan - 2010-06-05T08:25:44Z - cell - Markers are associated with mice. The Gr epitope is used to describe this cell type is found on both Ly6c and Ly6g. However, its the Ly6c that is considered the specific marker, and thus used in the cross-product. Also, this cell-type is sometimes described as being Gr1-negative. - Gr1-low non-classical monocyte - - - - A resident monocyte that is Gr-1 low, CD43-positive, and CX3CR1-positive. - GOC:tfm - PMID:8890901 - @@ -23011,22 +9126,7 @@ radial glial cells acting as neural progenitors throughout life. - A conventional thymic dendritic cell that is CD8alpha-positive. - tmeehan - 2010-06-07T02:48:36Z - CD8alpha-alpha-positive thymic conventional dendritic cell - DC.8+.Th - cell - CD8alpha-positive thymic conventional dendritic cell - - - - A conventional thymic dendritic cell that is CD8alpha-positive. - GOC:tfm - PMID:19273629 - http://www.immgen.org/index_content.html - @@ -23034,20 +9134,7 @@ radial glial cells acting as neural progenitors throughout life. - A melanin-containing macrophage that obtains the pigment by phagocytosis of melanosomes. - tmeehan - 2010-06-22T10:46:12Z - cell - melanophage - - - - A melanin-containing macrophage that obtains the pigment by phagocytosis of melanosomes. - GOC:tfm - PMID:20479296 - PMID:2943821 - @@ -23055,30 +9142,7 @@ radial glial cells acting as neural progenitors throughout life. - A T-helper cell that is characterized by secreting interleukin 9 and responding to helminth infections. This cell-type can derives from Th2 cells in the presence of TGF-beta and IL-4. Th2 cytokine production is surpressed. - tmeehan - 2010-06-22T11:18:44Z - T helper cells type 9 - T(H)-9 cell - Th9 - cell - T-helper 9 cell - - - - - A T-helper cell that is characterized by secreting interleukin 9 and responding to helminth infections. This cell-type can derives from Th2 cells in the presence of TGF-beta and IL-4. Th2 cytokine production is surpressed. - GOC:tfm - PMID:18931678 - PMID:19604299 - PMID:20154671 - - - - - Th9 - PMID:18931678 - + @@ -23086,34 +9150,7 @@ radial glial cells acting as neural progenitors throughout life. - A type I pneumocyte is a flattened, branched pneumocyte that covers more than 98% of the alveolar surface. This large cell has thin (50-100 nm) cytoplasmic extensions to form the air-blood barrier essential for normal gas exchange. - tmeehan - 2010-06-23T04:37:54Z - BTO:0000780 - FMA:62500 - AT1 - ATI - lung type 1 cells - membranous pneumocytes - pulmonary alveolar type I cell - small alveolar cells - squamous alveolar cell - squamous alveolar lining cell - type 1 alveolar epithelial cells - type 1 pneumocyte - type I alveolar cells - type I alveolar epithelial cells - cell - type I pneumocyte - - - - - A type I pneumocyte is a flattened, branched pneumocyte that covers more than 98% of the alveolar surface. This large cell has thin (50-100 nm) cytoplasmic extensions to form the air-blood barrier essential for normal gas exchange. - GOC:tfm - PMID:20054144 - http://www.copewithcytokines.de - + @@ -23123,37 +9160,7 @@ radial glial cells acting as neural progenitors throughout life. - A type II pneumocyte is a pneumocyte that modulates the fluid surrounding the alveolar epithelium by secreting and recycling surfactants. This cell type also contributes to tissue repair and can differentiate after injury into a type I pneumocyte. Thicker than squamous alveolar cells, have a rounded apical surface that projects above the level of surrounding epithelium. The free surface is covered by short microvilli. - tmeehan - 2010-06-24T12:04:13Z - BTO:0000538 - FMA:62501 - AT2 - ATII - TII - cuboidal type II cell - granular pneumocyte - great alveolar cell - lung type 2 cell - type 2 alveolar epithelial cell - type 2 alveolocyte - type 2 pneumocyte - type II alveolar cell - type II alveolar epithelial cell - type II alveolocyte - cell - lung type II cell - type II pneumocyte - - - - - A type II pneumocyte is a pneumocyte that modulates the fluid surrounding the alveolar epithelium by secreting and recycling surfactants. This cell type also contributes to tissue repair and can differentiate after injury into a type I pneumocyte. Thicker than squamous alveolar cells, have a rounded apical surface that projects above the level of surrounding epithelium. The free surface is covered by short microvilli. - GOC:tfm - ISBN:0412046911 - PMID:8540632 - http://www.copewithcytokines.de - + @@ -23162,25 +9169,7 @@ radial glial cells acting as neural progenitors throughout life. - A secretory cell found in pancreatic acini that secretes digestive enzymes and mucins. This cell is a typical zymogenic cell, have a basal nucleus and basophilic cytoplasm consisting of regular arrays of granular endoplasmic reticulum with mitochondria and dense secretory granules. - tmeehan - 2010-06-24T03:16:29Z - BTO:0000028 - CALOHA:TS-0737 - FMA:63032 - acinar cell of pancreas - cell - pancreatic acinar cell - - - - - A secretory cell found in pancreatic acini that secretes digestive enzymes and mucins. This cell is a typical zymogenic cell, have a basal nucleus and basophilic cytoplasm consisting of regular arrays of granular endoplasmic reticulum with mitochondria and dense secretory granules. - GOC:tfm - ISBN:0517223651 - PMID:20395539 - http://www.copewithcytokines.de/cope.cgi?key=pancreatic%20acinar%20cells - + @@ -23188,25 +9177,7 @@ radial glial cells acting as neural progenitors throughout life. - A neuroendocrine cell found in the epithelium of the lungs and respiratory tract. This cell type is rounded or elliptical in shape, situated mainly in the basal part of the epithelium; regulates bronchial secretion, smooth muscle contraction, lobular growth, ciliary activity and chemoreception. Cell has an electron-lucent cytoplasm, contains numerous dense-cored vesicles with a clear halo between the core and the limiting membrane. - tmeehan - 2010-06-28T08:24:30Z - P cell - FMA:14118 - Kultschitzky cell of bronchiole - bronchiolar Kulchitsky cell - respiratory enterochromaffin cell - cell - Feyrter cell - - - - - A neuroendocrine cell found in the epithelium of the lungs and respiratory tract. This cell type is rounded or elliptical in shape, situated mainly in the basal part of the epithelium; regulates bronchial secretion, smooth muscle contraction, lobular growth, ciliary activity and chemoreception. Cell has an electron-lucent cytoplasm, contains numerous dense-cored vesicles with a clear halo between the core and the limiting membrane. - GOC:tfm - ISBN:0412046911 - ISBN:0517223651 - + @@ -23215,20 +9186,7 @@ radial glial cells acting as neural progenitors throughout life. - An enterocrine cell that produces glucagon. - tmeehan - 2010-09-10T10:48:54Z - FMA:62939 - cell - type A enterocrine cell - - - - An enterocrine cell that produces glucagon. - GOC:tfm - ISBN:0412046911 - @@ -23236,25 +9194,7 @@ radial glial cells acting as neural progenitors throughout life. - Specialized cardiac myocyte that is subendocardially interspersed with the regular cardiac muscle cell. They are uninucleate cylindrical cells, associated end-to-end in long rows, continue from the node to the atrioventricular bundle; relatively short compared to ordinary myocytes but are nearly twice their diameter. - tmeehan - 2010-06-28T08:36:15Z - BTO:0001032 - FMA:14146 - Purkinje cell fiber - Purkinje muscle cell - myocytus conducens cardiacus - cell - Purkinje myocyte - - - - - Specialized cardiac myocyte that is subendocardially interspersed with the regular cardiac muscle cell. They are uninucleate cylindrical cells, associated end-to-end in long rows, continue from the node to the atrioventricular bundle; relatively short compared to ordinary myocytes but are nearly twice their diameter. - FMA:0412046911 - GOC:tfm - PMID:19939742 - + @@ -23262,23 +9202,7 @@ radial glial cells acting as neural progenitors throughout life. - Mostly cylindrical, resemble Type 1 in their contents and the presence of a kinocilium and stereocilium apically; much greater variation in size, some almost span the entire thickness of the sensory epithelium, while others are smaller than Type 1; receive multiple efferent nerve boutons around their bases as well as afferent endings, which are small expansions rather than chalices. - tmeehan - 2010-06-29T09:58:13Z - FMA:67909 - type 2 vestibular hair cell - type 2 vestibular sensory cell - type II hair cell - cell - type II vestibular sensory cell - - - - - Mostly cylindrical, resemble Type 1 in their contents and the presence of a kinocilium and stereocilium apically; much greater variation in size, some almost span the entire thickness of the sensory epithelium, while others are smaller than Type 1; receive multiple efferent nerve boutons around their bases as well as afferent endings, which are small expansions rather than chalices. - GOC:tfm - ISBN:0517223651 - + @@ -23286,23 +9210,7 @@ radial glial cells acting as neural progenitors throughout life. - Bottle-shaped with narrow neck; broad, rounded basal portion where nucleus is located; stereocilia and a single kinocilium is present apically; receive nerve bouton at their base from an afferent cup-shaped (chalice or calyx) nerve ending. - tmeehan - 2010-06-29T09:58:19Z - FMA:62352 - type 1 vestibular hair cell - type 1 vestibular sensory cell - type I hair cell - cell - type I vestibular sensory cell - - - - - Bottle-shaped with narrow neck; broad, rounded basal portion where nucleus is located; stereocilia and a single kinocilium is present apically; receive nerve bouton at their base from an afferent cup-shaped (chalice or calyx) nerve ending. - GOC:tfm - ISBN:0517223651 - + @@ -23311,25 +9219,7 @@ radial glial cells acting as neural progenitors throughout life. - Columnar cell which populate the epithelium of large intestine and absorb water. This cell is the most numerous of the epithelial cell types in the large intestine; bear apical microvilli, contain secretory granules in their apical cytoplasm; secretion appears to be largely mucins, but is also rich in antibodies of the IgA type. - tmeehan - 2010-06-29T11:07:25Z - columnar cell - BTO:0002484 - FMA:63638 - FMA:66771 - columnar cell of the colon - vacuolar absorptive cell - cell - enterocyte of epithelium of large intestine - - - - - Columnar cell which populate the epithelium of large intestine and absorb water. This cell is the most numerous of the epithelial cell types in the large intestine; bear apical microvilli, contain secretory granules in their apical cytoplasm; secretion appears to be largely mucins, but is also rich in antibodies of the IgA type. - GOC:tfm - ISBN:0517223651 - + @@ -23337,31 +9227,7 @@ radial glial cells acting as neural progenitors throughout life. - A specialized cardiac myocyte in the sinoatrial and atrioventricular nodes. The cell is slender and fusiform confined to the nodal center, circumferentially arranged around the nodal artery. - tmeehan - 2010-06-29T11:41:37Z - pacemaker cell - BTO:0004190 - FMA:67101 - P cell - cardiac pacemaker cell - myocytus nodalis - cell - nodal myocyte - - - - - A specialized cardiac myocyte in the sinoatrial and atrioventricular nodes. The cell is slender and fusiform confined to the nodal center, circumferentially arranged around the nodal artery. - FMA:67101 - GOC:tfm - - - - - cardiac pacemaker cell - GOC:pr - + @@ -23369,20 +9235,7 @@ radial glial cells acting as neural progenitors throughout life. - Specialized cardiac myocyte which is in the internodal tract and atrioventricular node. The cell is more slender than ordinary atrial myocytes and has more myofibrils than nodal myocytes. - tmeehan - 2010-06-29T02:39:32Z - FMA:67142 - cell - transitional myocyte - - - - Specialized cardiac myocyte which is in the internodal tract and atrioventricular node. The cell is more slender than ordinary atrial myocytes and has more myofibrils than nodal myocytes. - FMA:67142 - GOC:tfm - @@ -23391,20 +9244,7 @@ radial glial cells acting as neural progenitors throughout life. - The myoendocrine cellis a specialized myocyte localized mainly in the right and left atrial appendages, and also scattered within other areas of the atria and along the conductive system in the ventricular septum. The most conspicuous feature distinguishing myoendocrine cells from other atrial myoctyes is the presence of membane-bounded secretory granules (these granules contain precursor of cardiodilatins or atrial natriuretic polypeptides). - tmeehan - 2010-06-29T11:50:47Z - FMA:67111 - cell - myocardial endocrine cell - - - - The myoendocrine cellis a specialized myocyte localized mainly in the right and left atrial appendages, and also scattered within other areas of the atria and along the conductive system in the ventricular septum. The most conspicuous feature distinguishing myoendocrine cells from other atrial myoctyes is the presence of membane-bounded secretory granules (these granules contain precursor of cardiodilatins or atrial natriuretic polypeptides). - FMA:67111 - GOC:tfm - @@ -23413,21 +9253,7 @@ radial glial cells acting as neural progenitors throughout life. - Infrequent type of columnar epithelial cell. This cell is characterized by the presence of a tuft of blunt, squat microvilli (approximately 120-140/cell) on the cell surface. The microvilli contain filaments that stretch into the underlying cytoplasm. They have a distinctive pear shape with a wide base and a narrow microvillous apex. Function not known. - tmeehan - 2010-06-29T03:22:46Z - cell - pulmonary brush cell - brush cell of trachebronchial tree - - - - Infrequent type of columnar epithelial cell. This cell is characterized by the presence of a tuft of blunt, squat microvilli (approximately 120-140/cell) on the cell surface. The microvilli contain filaments that stretch into the underlying cytoplasm. They have a distinctive pear shape with a wide base and a narrow microvillous apex. Function not known. - GOC:tfm - ISBN:0517223651 - PMID:15817800 - @@ -23436,20 +9262,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell derived from endoderm. - tmeehan - 2010-06-29T03:38:14Z - FMA:69075 - cell - endo-epithelial cell - - - - An epithelial cell derived from endoderm. - FMA:69075 - GOC:tfm - @@ -23458,20 +9271,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell derived from ectoderm. - tmeehan - 2010-06-29T03:38:22Z - FMA:69074 - cell - ecto-epithelial cell - - - - An epithelial cell derived from ectoderm. - FMA:69074 - GOC:tfm - @@ -23480,21 +9280,7 @@ radial glial cells acting as neural progenitors throughout life. - Epithelial cell derived from mesoderm or mesenchyme. - tmeehan - 2010-06-29T03:49:14Z - FMA:69076 - epithelial mesenchymal cell - cell - meso-epithelial cell - - - - Epithelial cell derived from mesoderm or mesenchyme. - FMA:69076 - GOC:tfm - @@ -23503,21 +9289,7 @@ radial glial cells acting as neural progenitors throughout life. - Epithelial cell found in the ducts of the pancreas. This cell type contributes to the high luminal pH. - tmeehan - 2010-06-30T08:49:43Z - FMA:63099 - cell - pancreatic ductal cell - - - - Epithelial cell found in the ducts of the pancreas. This cell type contributes to the high luminal pH. - FMA:63099 - GOC:tfm - PMID:14740223 - @@ -23525,24 +9297,7 @@ radial glial cells acting as neural progenitors throughout life. - A cubodial epithelial cell that is continuous with the lining of intercalated ducts that drain the acinus. This cell type secretes a high pH solution to aid in activation of zymogens, and can differentiate into endocrine and exocrine pancreatic cell types. - tmeehan - 2010-06-30T08:49:52Z - FMA:62455 - centroacinar cell of Langerhans - pancreatic centroacinar cell - cell - pancreatic centro-acinar cell - - - - - A cubodial epithelial cell that is continuous with the lining of intercalated ducts that drain the acinus. This cell type secretes a high pH solution to aid in activation of zymogens, and can differentiate into endocrine and exocrine pancreatic cell types. - GOC:tfm - PMID:12142741 - PMID:20018761 - PMID:8185160 - + @@ -23551,22 +9306,7 @@ radial glial cells acting as neural progenitors throughout life. - This cell resembles a glia cell, express the glial marker S100 and act as a supporting cell to type I cell. This cell is located in a small cluster of type I and type II cells near the fork of the carotid artery. - tmeehan - 2010-06-30T04:23:42Z - FMA:84187 - sheath cell of carotid body - cell - type II cell of carotid body - - - - This cell resembles a glia cell, express the glial marker S100 and act as a supporting cell to type I cell. This cell is located in a small cluster of type I and type II cells near the fork of the carotid artery. - GOC:tfm - PMID:7938227 - http://en.wikipedia.org/wiki/Carotid_body - @@ -23575,22 +9315,7 @@ radial glial cells acting as neural progenitors throughout life. - A chromaffin cell of the adrenal medulla that produces epinephrine. - tmeehan - 2010-07-14T09:41:42Z - FMA:69322 - adremergic chromaffin cell - adrenal secreting cell of the adrenal medulla - epiniphrine secreting cell of the adrenal medulla - cell - type II cell of adrenal medulla - - - - A chromaffin cell of the adrenal medulla that produces epinephrine. - GOC:tfm - @@ -23599,21 +9324,7 @@ radial glial cells acting as neural progenitors throughout life. - A chromaffin cell of the adrenal medulla that produces norepinephrine. - tmeehan - 2010-07-14T10:12:24Z - FMA:69321 - noradrenergic chromaffin cell - cell - type I cell of adrenal medulla - - - - A chromaffin cell of the adrenal medulla that produces norepinephrine. - GOC:tfm - ISBN:068340007X - @@ -23621,22 +9332,7 @@ radial glial cells acting as neural progenitors throughout life. - A Boettcher cell is a polyhedral cells on the basilar membrane of the cochlea, and is located beneath Claudius cells. A Boettcher cell is considered a supporting cell for the organ of Corti, and is present only in the lower turn of the cochlea. These cells interweave with each other, and project microvilli into the intercellular space. Because of their structural specialization, a Boettcher cell is believed to play a significant role in the function of the cochlea. They demonstrate high levels of calmodulin, and may be involved in mediating Ca(2+) regulation and ion transport. - tmeehan - 2010-07-14T03:22:02Z - Boettcher's cell - Bottcher cell - Bottcher's cell - cell - Boettcher cell - - - - A Boettcher cell is a polyhedral cells on the basilar membrane of the cochlea, and is located beneath Claudius cells. A Boettcher cell is considered a supporting cell for the organ of Corti, and is present only in the lower turn of the cochlea. These cells interweave with each other, and project microvilli into the intercellular space. Because of their structural specialization, a Boettcher cell is believed to play a significant role in the function of the cochlea. They demonstrate high levels of calmodulin, and may be involved in mediating Ca(2+) regulation and ion transport. - GOC:tfm - http://en.wikipedia.org/wiki/Boettcher_cell - @@ -23644,23 +9340,7 @@ radial glial cells acting as neural progenitors throughout life. - Specialized elongated ventricular ependymal cell that has processes that extend to the outer, or pial, surface of the CNS. Resemble spongioblasts seen in developing brain. Found in the adult brain in the third ventricle, cerebral aqueduct, spinal canal and floor of the fourth ventricle. - tmeehan - 2010-07-15T11:21:11Z - CL:0000643 - BTO:0001953 - FMA:54560 - stretch cell - cell - tanycyte - - - - - Specialized elongated ventricular ependymal cell that has processes that extend to the outer, or pial, surface of the CNS. Resemble spongioblasts seen in developing brain. Found in the adult brain in the third ventricle, cerebral aqueduct, spinal canal and floor of the fourth ventricle. - GOC:tfm - http://neurolex.org/wiki/Category:Tanycyte - + @@ -23668,20 +9348,7 @@ radial glial cells acting as neural progenitors throughout life. - A cardiac myocyte that is an excitable cells in the myocardium, specifically in the conducting system of heart. - tmeehan - 2010-07-21T01:33:38Z - FMA:67968 - cell - specialized cardiac myocyte - - - - A cardiac myocyte that is an excitable cells in the myocardium, specifically in the conducting system of heart. - FMA:67968 - GOC:tfm - @@ -23689,20 +9356,7 @@ radial glial cells acting as neural progenitors throughout life. - A leukocyte that lacks granules. - tmeehan - 2010-07-22T11:30:33Z - FMA:62855 - agranular leukocyte - cell - nongranular leukocyte - - - - A leukocyte that lacks granules. - GOC:tfm - @@ -23710,31 +9364,7 @@ radial glial cells acting as neural progenitors throughout life. - This is a cell found in the gastrointestinal tract of mammals and serves as a pacemaker that triggers gut contraction. ICCs mediate inputs from the enteric nervous system to smooth muscle cells and are thought to be the cells from which gastrointestinal stromal tumors (GISTs) arise. - tmeehan - 2010-07-22T03:26:00Z - BTO:0003914 - FMA:86573 - ICC - intestinal pacemaker cell - cell - Some argue this cell type is of mesenchymal origin. - interstitial cell of Cajal - - - - - This is a cell found in the gastrointestinal tract of mammals and serves as a pacemaker that triggers gut contraction. ICCs mediate inputs from the enteric nervous system to smooth muscle cells and are thought to be the cells from which gastrointestinal stromal tumors (GISTs) arise. - GOC:tfm - PMID:16460275 - PMID:19520112 - - - - - intestinal pacemaker cell - GOC:pr - + @@ -23742,21 +9372,7 @@ radial glial cells acting as neural progenitors throughout life. - A group 2 innate lymphoid cell in the mouse capable of secreting IL-13 in response to a helminth infection. This cell is lineage-negative, ICOS-positive, IL1RL1-positive, IL7Ralpha-positive, and IL17Br-positive. - tmeehan - 2010-08-12T02:22:19Z - nuocyte - cell - group 2 innate lymphoid cell, mouse - - - - A group 2 innate lymphoid cell in the mouse capable of secreting IL-13 in response to a helminth infection. This cell is lineage-negative, ICOS-positive, IL1RL1-positive, IL7Ralpha-positive, and IL17Br-positive. - GOC:add - GOC:tfm - PMID:20200518 - @@ -23764,24 +9380,7 @@ radial glial cells acting as neural progenitors throughout life. - One of two small cells formed by the first and second meiotic division of oocytes. - tmeehan - 2010-08-23T09:49:53Z - EHDAA2:0004716 - FMA:85543 - WBbt:0008429 - XAO:0000262 - cell - polar body - - - - - One of two small cells formed by the first and second meiotic division of oocytes. - GOC:tfm - ISBN:068340007X - http://en.wikipedia.org/wiki/Polar_body - + @@ -23789,37 +9388,7 @@ radial glial cells acting as neural progenitors throughout life. - A small cell formed by the first meiotic division of oocytes. - tmeehan - 2010-08-23T09:49:58Z - EHDAA2:0000541 - EMAPA:16032 - FMA:18650 - VHOG:0000464 - first polar body - polocytus primarius - cell - primary polar body - - - - - A small cell formed by the first meiotic division of oocytes. - GOC:tfm - ISBN:068340007X - - - - - first polar body - EHDAA2:0000541 - - - - - polocytus primarius - FMA:18650 - + @@ -23827,22 +9396,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell found in the bone marrow. This can include fibroblasts, macrophages, adipocytes, osteoblasts, osteoclasts, endothelial cells and hematopoietic cells. - tmeehan - 2010-07-22T04:48:15Z - BTO:0004850 - FMA:83621 - cell - MH consider whether bone marrow cells are bone cells in the structural sense vs. being part of bone organ sense. - bone marrow cell - - - - A cell found in the bone marrow. This can include fibroblasts, macrophages, adipocytes, osteoblasts, osteoclasts, endothelial cells and hematopoietic cells. - GOC:tfm - ISBN:0618947256 - @@ -23850,37 +9404,7 @@ radial glial cells acting as neural progenitors throughout life. - A small cell formed by the second meiotic division of oocytes. In mammals, the second polar body may fail to form unless the ovum has been penetrated by a sperm cell. - tmeehan - 2010-08-23T09:50:01Z - EHDAA2:0001820 - EMAPA:16034 - EMAPA:16045 - FMA:18651 - polocytus secundarius - second polar body - cell - secondary polar body - - - - - A small cell formed by the second meiotic division of oocytes. In mammals, the second polar body may fail to form unless the ovum has been penetrated by a sperm cell. - GOC:tfm - ISBN:068340007X - - - - - polocytus secundarius - FMA:18651 - - - - - second polar body - EHDAA2:0001820 - + @@ -23888,19 +9412,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell that makes up the loose connective tissue of the ovary. - tmeehan - 2010-08-23T11:11:34Z - FMA:18709 - cell - interstitial cell of ovary - - - - A cell that makes up the loose connective tissue of the ovary. - GOC:tfm - @@ -23909,21 +9421,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell in the hilum of the ovary that produces androgens. - tmeehan - 2010-08-23T11:18:18Z - FMA:18710 - hilar cell of ovary - cell - hilus cell of ovary - - - - A cell in the hilum of the ovary that produces androgens. - GOC:tfm - ISBN:068340007X - @@ -23931,20 +9429,7 @@ radial glial cells acting as neural progenitors throughout life. - A specialised myocyte that lies between the sinoatrial node and the atrioventricular node and is involved in the conduction of electrical signals. - tmeehan - 2010-08-23T11:24:11Z - FMA:223275 - cell - internodal tract myocyte - - - - A specialised myocyte that lies between the sinoatrial node and the atrioventricular node and is involved in the conduction of electrical signals. - GOC:tfm - ISBN:0781729300 - @@ -23954,21 +9439,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell of the adrenal cortex. Cell types include those that synthesize and secrete chemical derivatives (steroids) of cholesterol. - tmeehan - 2010-08-24T01:37:44Z - FMA:69545 - adrenal cortex cell - adrenocortical cell - cell - cortical cell of adrenal gland - - - - A cell of the adrenal cortex. Cell types include those that synthesize and secrete chemical derivatives (steroids) of cholesterol. - GOC:tfm - @@ -23976,21 +9447,7 @@ radial glial cells acting as neural progenitors throughout life. - A cardiac myocyte that is connected to other cardiac myocytes by transverse intercalated discs (GO:0014704) at a regular interval. - tmeehan - 2010-08-23T11:33:10Z - FMA:67967 - regular cardiac muscle cell - regular cardiac muscle fiber - cell - regular cardiac myocyte - - - - A cardiac myocyte that is connected to other cardiac myocytes by transverse intercalated discs (GO:0014704) at a regular interval. - GOC:tfm - @@ -23999,22 +9456,7 @@ radial glial cells acting as neural progenitors throughout life. - A small, polyhedral, cell found in rounded groups or curved columns with deeply staining nuclei, scanty basophilic cytoplasm and a few lipid droplets. This cell in the zona glomerulosa produces mineralocorticoids. - tmeehan - 2010-08-24T01:42:02Z - CL:1000423 - FMA:69273 - epithelial cell of zona glomerulosa of adrenal gland - cell - type I cell of adrenal cortex - - - - A small, polyhedral, cell found in rounded groups or curved columns with deeply staining nuclei, scanty basophilic cytoplasm and a few lipid droplets. This cell in the zona glomerulosa produces mineralocorticoids. - GOC:tfm - ISBN:0517223651 - @@ -24022,19 +9464,7 @@ radial glial cells acting as neural progenitors throughout life. - A regular cardiac myocyte of the interventricular region of the heart. - tmeehan - 2010-08-23T11:40:52Z - FMA:228792 - cell - regular interventricular cardiac myocyte - - - - A regular cardiac myocyte of the interventricular region of the heart. - GOC:tfm - @@ -24042,26 +9472,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD38-positive naive B cell is a mature B cell that has the phenotype CD38-positive, surface IgD-positive, surface IgM-positive, and CD27-negative, and that has not yet been activated by antigen in the periphery. - CD38+ naive B cell - CD38+ naive B lymphocyte - CD38+ naive B-cell - CD38+ naive B-lymphocyte - CD38-positive naive B lymphocyte - CD38-positive naive B-cell - CD38-positive naive B-lymphocyte - cell - CD38-positive naive B cell - - - - - A CD38-positive naive B cell is a mature B cell that has the phenotype CD38-positive, surface IgD-positive, surface IgM-positive, and CD27-negative, and that has not yet been activated by antigen in the periphery. - GOC:dsd - GOC:rhs - GOC:tfm - PMID:20123131 - + @@ -24069,26 +9480,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD38-negative naive B cell is a mature B cell that has the phenotype CD38-negative, surface IgD-positive, surface IgM-positive, and CD27-negative, that has not yet been activated by antigen in the periphery. - CD38- naive B cell - CD38- naive B lymphocyte - CD38- naive B-cell - CD38- naive B-lymphocyte - CD38-negative naive B lymphocyte - CD38-negative naive B-cell - CD38-negative naive B-lymphocyte - cell - CD38-negative naive B cell - - - - - A CD38-negative naive B cell is a mature B cell that has the phenotype CD38-negative, surface IgD-positive, surface IgM-positive, and CD27-negative, that has not yet been activated by antigen in the periphery. - GOC:dsd - GOC:rhs - GOC:tfm - PMID:20123131 - + @@ -24096,34 +9488,7 @@ radial glial cells acting as neural progenitors throughout life. - An IgG-positive double negative memory B cell is a double negative memory B cell with the phenotype IgG-positive, IgD-negative, and CD27-negative. - IgG+ dn memory B cell - IgG+ dn memory B lymphocyte - IgG+ dn memory B-cell - IgG+ dn memory B-lymphocyte - IgG+ double negative memory B cell - IgG+ double negative memory B lymphocyte - IgG+ double negative memory B-cell - IgG+ double negative memory B-lymphocyte - IgG-positive dn memory B cell - IgG-positive dn memory B lymphocyte - IgG-positive dn memory B-cell - IgG-positive dn memory B-lymphocyte - IgG-positive double negative memory B lymphocyte - IgG-positive double negative memory B-cell - IgG-positive double negative memory B-lymphocyte - cell - IgG-positive double negative memory B cell - - - - - An IgG-positive double negative memory B cell is a double negative memory B cell with the phenotype IgG-positive, IgD-negative, and CD27-negative. - GOC:dsd - GOC:rhs - GOC:tfm - PMID:20123131 - + @@ -24131,34 +9496,7 @@ radial glial cells acting as neural progenitors throughout life. - An IgG-negative double negative memory B cell is a double negative memory B cell with the phenotype IgG-negative, IgD-negative, and CD27-negative. - IgG- dn memory B cell - IgG- dn memory B lymphocyte - IgG- dn memory B-cell - IgG- dn memory B-lymphocyte - IgG- double negative memory B cell - IgG- double negative memory B lymphocyte - IgG- double negative memory B-cell - IgG- double negative memory B-lymphocyte - IgG-negative dn memory B cell - IgG-negative dn memory B lymphocyte - IgG-negative dn memory B-cell - IgG-negative dn memory B-lymphocyte - IgG-negative double negative memory B lymphocyte - IgG-negative double negative memory B-cell - IgG-negative double negative memory B-lymphocyte - cell - IgG-negative double negative memory B cell - - - - - An IgG-negative double negative memory B cell is a double negative memory B cell with the phenotype IgG-negative, IgD-negative, and CD27-negative. - GOC:dsd - GOC:rhs - GOC:tfm - PMID:20123131 - + @@ -24166,26 +9504,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD38-positive IgG memory B cell is a class switched memory B cell that expresses IgG on the cell surface with the phenotype CD38-positive and IgG-positive. - CD38+ IgG memory B cell - CD38+ IgG memory B lymphocyte - CD38+ IgG memory B-cell - CD38+ IgG memory B-lymphocyte - CD38-positive IgG memory B lymphocyte - CD38-positive IgG memory B-cell - CD38-positive IgG memory B-lymphocyte - cell - CD38-positive IgG memory B cell - - - - - A CD38-positive IgG memory B cell is a class switched memory B cell that expresses IgG on the cell surface with the phenotype CD38-positive and IgG-positive. - GOC:dsd - GOC:rhs - GOC:tfm - PMID:20123131 - + @@ -24193,19 +9512,7 @@ radial glial cells acting as neural progenitors throughout life. - An IgD-positive CD38-positive IgG memory B cell is a CD38-positive IgG-positive class switched memory B cell that has class switched and expresses IgD on the cell surface with the phenotype IgD-positive, CD38-positive, and IgG-positive. - cell - IgD-positive CD38-positive IgG memory B cell - - - - An IgD-positive CD38-positive IgG memory B cell is a CD38-positive IgG-positive class switched memory B cell that has class switched and expresses IgD on the cell surface with the phenotype IgD-positive, CD38-positive, and IgG-positive. - GOC:dsd - GOC:rhs - GOC:tfm - PMID:20123131 - @@ -24214,19 +9521,7 @@ radial glial cells acting as neural progenitors throughout life. - An IgD-negative CD38-positive IgG memory B cell is a CD38-positive IgG-positive that has class switched and lacks expression of IgD on the cell surface with the phenotype IgD-negative, CD38-positive, and IgG-positive. - cell - IgD-negative CD38-positive IgG memory B cell - - - - An IgD-negative CD38-positive IgG memory B cell is a CD38-positive IgG-positive that has class switched and lacks expression of IgD on the cell surface with the phenotype IgD-negative, CD38-positive, and IgG-positive. - GOC:dsd - GOC:rhs - GOC:tfm - PMID:20123131 - @@ -24235,19 +9530,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD38-negative IgG memory B cell is a IgG-positive class switched memory B cell that has class switched and expresses IgG on the cell surface with the phenotype CD38-negative, IgD-negative, and IgG-positive. - cell - CD38-negative IgG memory B cell - - - - A CD38-negative IgG memory B cell is a IgG-positive class switched memory B cell that has class switched and expresses IgG on the cell surface with the phenotype CD38-negative, IgD-negative, and IgG-positive. - GOC:dsd - GOC:rhs - GOC:tfm - PMID:20123131 - @@ -24255,30 +9538,7 @@ radial glial cells acting as neural progenitors throughout life. - A B220-positive CD38-positive naive B cell is a CD38-positive naive B cell that has the phenotype B220-positive, CD38-positive, surface IgD-positive, surface IgM-positive, and CD27-negative, and that has not yet been activated by antigen in the periphery. - B220+CD38+ naive B cell - B220+CD38+ naive B lymphocyte - B220+CD38+ naive B-cell - B220+CD38+ naive B-lymphocyte - B220-positive CD38-positive naive B lymphocyte - B220-positive CD38-positive naive B-cell - B220-positive CD38-positive naive B-lymphocyte - CD38+B220+ naive B cell - CD38+B220+ naive B lymphocyte - CD38+B220+ naive B-cell - CD38+B220+ naive B-lymphocyte - cell - B220-positive CD38-positive naive B cell - - - - - A B220-positive CD38-positive naive B cell is a CD38-positive naive B cell that has the phenotype B220-positive, CD38-positive, surface IgD-positive, surface IgM-positive, and CD27-negative, and that has not yet been activated by antigen in the periphery. - GOC:dsd - GOC:rhs - GOC:tfm - PMID:20123131 - + @@ -24286,19 +9546,7 @@ radial glial cells acting as neural progenitors throughout life. - A B220-low CD38-positive naive B cell is a CD38-positive naive B cell that has the phenotype B220-low, CD38-positive, surface IgD-positive, surface IgM-positive, and CD27-negative, that has not yet been activated by antigen in the periphery. - cell - B220-low CD38-positive naive B cell - - - - A B220-low CD38-positive naive B cell is a CD38-positive naive B cell that has the phenotype B220-low, CD38-positive, surface IgD-positive, surface IgM-positive, and CD27-negative, that has not yet been activated by antigen in the periphery. - GOC:dsd - GOC:rhs - GOC:tfm - PMID:20123131 - @@ -24306,26 +9554,7 @@ radial glial cells acting as neural progenitors throughout life. - An CD38-negative unswitched memory B cell is an unswitched memory B cell that has the phenotype CD38-negative, IgD-positive, CD138-negative, and IgG-negative. - CD38- unswitched memory B cell - CD38- unswitched memory B lymphocyte - CD38- unswitched memory B-cell - CD38- unswitched memory B-lymphocyte - CD38-negative unswitched memory B lymphocyte - CD38-negative unswitched memory B-cell - CD38-negative unswitched memory B-lymphocyte - cell - CD38-negative unswitched memory B cell - - - - - An CD38-negative unswitched memory B cell is an unswitched memory B cell that has the phenotype CD38-negative, IgD-positive, CD138-negative, and IgG-negative. - GOC:dsd - GOC:rhs - GOC:tfm - PMID:20123131 - + @@ -24333,19 +9562,7 @@ radial glial cells acting as neural progenitors throughout life. - A B220-positive CD38-negative unswitched memory B cell is a CD38-negative unswitched memory B cell that has the phenotype B220-positive, CD38-negative, IgD-positive, CD138-negative, and IgG-negative. - cell - B220-positive CD38-negative unswitched memory B cell - - - - A B220-positive CD38-negative unswitched memory B cell is a CD38-negative unswitched memory B cell that has the phenotype B220-positive, CD38-negative, IgD-positive, CD138-negative, and IgG-negative. - GOC:dsd - GOC:rhs - GOC:tfm - PMID:20123131 - @@ -24353,19 +9570,7 @@ radial glial cells acting as neural progenitors throughout life. - A B220-low CD38-negative unswitched memory B cell is a CD38-negative unswitched memory B cell that has the phenotype B220-low, CD38-negative, IgD-positive, CD138-negative, and IgG-negative. - cell - B220-low CD38-negative unswitched memory B cell - - - - A B220-low CD38-negative unswitched memory B cell is a CD38-negative unswitched memory B cell that has the phenotype B220-low, CD38-negative, IgD-positive, CD138-negative, and IgG-negative. - GOC:dsd - GOC:rhs - GOC:tfm - PMID:20123131 - @@ -24373,26 +9578,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD38-positive unswitched memory B cell is an unswitched memory B cell that has the phenotype CD38-positive, IgD-positive, CD138-negative, and IgG-negative. - CD38+ unswitched memory B cell - CD38+ unswitched memory B lymphocyte - CD38+ unswitched memory B-cell - CD38+ unswitched memory B-lymphocyte - CD38-positive unswitched memory B lymphocyte - CD38-positive unswitched memory B-cell - CD38-positive unswitched memory B-lymphocyte - cell - CD38-positive unswitched memory B cell - - - - - A CD38-positive unswitched memory B cell is an unswitched memory B cell that has the phenotype CD38-positive, IgD-positive, CD138-negative, and IgG-negative. - GOC:dsd - GOC:rhs - GOC:tfm - PMID:20123131 - + @@ -24400,19 +9586,7 @@ radial glial cells acting as neural progenitors throughout life. - A B220-positive CD38-positive unswitched memory B cell is a CD38-positive unswitched memory B cell that has the phenotype B220-positive, CD38-positive, IgD-positive, CD138-negative, and IgG-negative. - cell - B220-positive CD38-positive unswitched memory B cell - - - - A B220-positive CD38-positive unswitched memory B cell is a CD38-positive unswitched memory B cell that has the phenotype B220-positive, CD38-positive, IgD-positive, CD138-negative, and IgG-negative. - GOC:dsd - GOC:rhs - GOC:tfm - PMID:20123131 - @@ -24420,19 +9594,7 @@ radial glial cells acting as neural progenitors throughout life. - A B220-low CD38-positive unswitched memory B cell is a CD38-positive unswitched memory B cell that has the phenotype B220-low, CD38-positive, IgD-positive, CD138-negative, and IgG-negative. - cell - B220-low CD38-positive unswitched memory B cell - - - - A B220-low CD38-positive unswitched memory B cell is a CD38-positive unswitched memory B cell that has the phenotype B220-low, CD38-positive, IgD-positive, CD138-negative, and IgG-negative. - GOC:dsd - GOC:rhs - GOC:tfm - PMID:20123131 - @@ -24440,26 +9602,7 @@ radial glial cells acting as neural progenitors throughout life. - A class switched memory B cell that lacks IgG on the cell surface. - IgG- class switched memory B cell - IgG- class switched memory B lymphocyte - IgG- class switched memory B-cell - IgG- class switched memory B-lymphocyte - IgG-negative class switched memory B lymphocyte - IgG-negative class switched memory B-cell - IgG-negative class switched memory B-lymphocyte - cell - IgG-negative class switched memory B cell - - - - - A class switched memory B cell that lacks IgG on the cell surface. - GOC:dsd - GOC:rhs - GOC:tfm - PMID:20123131 - + @@ -24467,19 +9610,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD38-negative IgG-negative memory B cell is a IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD38-negative and IgG-negative. - cell - CD38-negative IgG-negative class switched memory B cell - - - - A CD38-negative IgG-negative memory B cell is a IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD38-negative and IgG-negative. - GOC:dsd - GOC:rhs - GOC:tfm - PMID:20123131 - @@ -24487,19 +9618,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD38-positive IgG-negative memory B cell is an IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD38-positive and IgG-negative. - cell - CD38-positive IgG-negative class switched memory B cell - - - - A CD38-positive IgG-negative memory B cell is an IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD38-positive and IgG-negative. - GOC:dsd - GOC:rhs - GOC:tfm - PMID:20123131 - @@ -24507,19 +9626,7 @@ radial glial cells acting as neural progenitors throughout life. - An CD24-positive CD38-negative IgG-negative memory B cell is a CD38-negative IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD24-positive, CD38-negative, and IgG-negative. - cell - CD24-positive CD38-negative IgG-negative class switched memory B cell - - - - An CD24-positive CD38-negative IgG-negative memory B cell is a CD38-negative IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD24-positive, CD38-negative, and IgG-negative. - GOC:dsd - GOC:rhs - GOC:tfm - PMID:20123131 - @@ -24527,19 +9634,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD24-negative CD38-negative IgG-negative memory B cell is a CD38-negative IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD24-negative, CD38-negative, and IgG-negative. - cell - CD24-negative CD38-negative IgG-negative class switched memory B cell - - - - A CD24-negative CD38-negative IgG-negative memory B cell is a CD38-negative IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD24-negative, CD38-negative, and IgG-negative. - GOC:dsd - GOC:rhs - GOC:tfm - PMID:20123131 - @@ -24547,19 +9642,7 @@ radial glial cells acting as neural progenitors throughout life. - A B220-positive CD38-positive IgG-negative memory B cell is a CD38-positive IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype B220-positive, CD38-positive, and IgG-negative. - cell - B220-positive CD38-positive IgG-negative class switched memory B cell - - - - A B220-positive CD38-positive IgG-negative memory B cell is a CD38-positive IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype B220-positive, CD38-positive, and IgG-negative. - GOC:dsd - GOC:rhs - GOC:tfm - PMID:20123131 - @@ -24567,19 +9650,7 @@ radial glial cells acting as neural progenitors throughout life. - A B220-low CD38-positive IgG-negative memory B cell is a CD38-positive IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype B220-low, CD38-positive, and IgG-positive. - cell - B220-low CD38-positive IgG-negative class switched memory B cell - - - - A B220-low CD38-positive IgG-negative memory B cell is a CD38-positive IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype B220-low, CD38-positive, and IgG-positive. - GOC:dsd - GOC:rhs - GOC:tfm - PMID:20123131 - @@ -24588,22 +9659,7 @@ radial glial cells acting as neural progenitors throughout life. - A circulating gamma-delta T cell that is CD27-positive and capable of producing IFN-gamma. - tmeehan - 2010-08-18T09:57:19Z - gammadelta27-positive - gd27-positive - cell - CD27-positive gamma-delta T cell - - - - A circulating gamma-delta T cell that is CD27-positive and capable of producing IFN-gamma. - GOC:dsd - GOC:tfm - PMID:19270712 - @@ -24612,27 +9668,7 @@ radial glial cells acting as neural progenitors throughout life. - A circulating gamma-delta T cell that expresses RORgamma(t), is CD27-negative and is capable of IL-17 secretion. - tmeehan - 2010-08-18T09:57:29Z - gammadelta-17 cells - cell - CD27-negative gamma-delta T cell - - - - - A circulating gamma-delta T cell that expresses RORgamma(t), is CD27-negative and is capable of IL-17 secretion. - GOC:dsd - GOC:tfm - PMID:19270712 - - - - - gammadelta-17 cells - PMID:21976777 - + @@ -24641,19 +9677,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD25-positive, CD27-positive immature gamma-delta T cell found in the thymus that has an immature phenotype (i.e. CD24-high, CD25-high, CD62L-high, CD44-high, CD2-low, CD5-low). - tmeehan - 2010-08-18T10:35:37Z - cell - CD25-positive, CD27-positive immature gamma-delta T cell - - - - A CD25-positive, CD27-positive immature gamma-delta T cell found in the thymus that has an immature phenotype (i.e. CD24-high, CD25-high, CD62L-high, CD44-high, CD2-low, CD5-low). - GOC:tfm - PMID:19270712 - @@ -24661,19 +9685,7 @@ radial glial cells acting as neural progenitors throughout life. - A T cell with a receptor of limited diversity that is capable of immediate effector functions upon stimulation. - tmeehan - 2010-08-20T02:14:25Z - cell - innate effector T cell - - - - A T cell with a receptor of limited diversity that is capable of immediate effector functions upon stimulation. - GOC:tfm - PMID:20581831 - @@ -24681,32 +9693,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD8-positive, alpha-beta T cell that has the phenotype CXCR3-negative, CCR6-positive, CCR5-high, CD45RA-negative, and capable of producing IL-17 and some IFNg. - Tc17 CD8+ T cell - Tc17 T cell - Tc17 T lymphocyte - Tc17 T-cell - Tc17 T-lymphocyte - cell - This cell type is compatible with the HIPC Lyoplate markers for 'Tc17 CD8+ T cell', but its logical definition includes additional known characteristics of Tc17 T cells. Found in the CD27-positive, CD28-positive or CD27-negative, CD28-positive fractions with the phenotype CCR4-negative and CCR7-negative (this sentence not part of definition). - Tc17 cell - - - - - A CD8-positive, alpha-beta T cell that has the phenotype CXCR3-negative, CCR6-positive, CCR5-high, CD45RA-negative, and capable of producing IL-17 and some IFNg. - GOC:add - GOC:dsd - GOC:tfm - PMID:19201830 - PMID:22343568 - - - - - Tc17 CD8+ T cell - PMID:22343568 - + @@ -24714,29 +9701,7 @@ radial glial cells acting as neural progenitors throughout life. - Regular cardiac myocyte of a cardiac atrium. - tmeehan - 2010-08-23T11:41:03Z - FMA:83108 - atrial cardiac muscle cell - atrial myocyte - regular atrial cardiac muscle fiber - regular cardiac muscle cell of atrium - cell - regular atrial cardiac myocyte - - - - - Regular cardiac myocyte of a cardiac atrium. - GOC:tfm - - - - - atrial cardiac muscle cell - GOC:pr - + @@ -24744,19 +9709,7 @@ radial glial cells acting as neural progenitors throughout life. - A cardiac myocyte of the interatrial region of the heart. - tmeehan - 2010-08-23T11:41:09Z - FMA:228790 - cell - regular interatrial cardiac myocyte - - - - A cardiac myocyte of the interatrial region of the heart. - GOC:tfm - @@ -24764,29 +9717,7 @@ radial glial cells acting as neural progenitors throughout life. - Regular cardiac myocyte of a cardiac ventricle. - tmeehan - 2010-08-23T11:41:13Z - ventricular cardiac muscle cell - FMA:83109 - regular cardiac muscle cell of ventricle - regular ventricular cardiac muscle fiber - ventricular myocyte - cell - regular ventricular cardiac myocyte - - - - - Regular cardiac myocyte of a cardiac ventricle. - GOC:tfm - - - - - ventricular cardiac muscle cell - GOC:pr - + @@ -24794,26 +9725,7 @@ radial glial cells acting as neural progenitors throughout life. - A stomal cell of the ovary - tmeehan - 2010-08-23T12:10:31Z - FMA:72299 - ovarian stromal cell - cell - stromal cell of ovary - - - - - A stomal cell of the ovary - GOC:tfm - - - - - ovarian stromal cell - GOC:cjm - + @@ -24821,19 +9733,7 @@ radial glial cells acting as neural progenitors throughout life. - A stromal cell of the ovarian cortex. - tmeehan - 2010-08-23T12:12:15Z - FMA:256169 - cell - stromal cell of ovarian cortex - - - - A stromal cell of the ovarian cortex. - GOC:tfm - @@ -24841,19 +9741,7 @@ radial glial cells acting as neural progenitors throughout life. - A stromal cell of the ovarian medulla. - tmeehan - 2010-08-23T12:12:17Z - FMA:256171 - cell - stromal cell of ovarian medulla - - - - A stromal cell of the ovarian medulla. - GOC:tfm - @@ -24861,20 +9749,7 @@ radial glial cells acting as neural progenitors throughout life. - Epidermal cells that do not contain keratin. Cell type is usually associated with moist epidermal tissues. - tmeehan - 2010-08-24T08:43:27Z - FMA:62880 - cell - nonkeratinized cell of epidermis - - - - Epidermal cells that do not contain keratin. Cell type is usually associated with moist epidermal tissues. - GO:tfm - PMID:1987287 - @@ -24883,21 +9758,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell in the zona fasciculata that produce glucocorticoids, e.g cortisol. - tmeehan - 2010-08-24T01:50:42Z - FMA:69547 - type II cortical cell of adrenal gland - cell - type II cell of adrenal cortex - - - - A cell in the zona fasciculata that produce glucocorticoids, e.g cortisol. - GOC:tfm - ISBN:0517223651 - @@ -24906,20 +9767,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell in the zona reticularis that produce sex hormones. - tmeehan - 2010-08-24T01:50:44Z - FMA:69564 - cell - type III cell of adrenal cortex - - - - A cell in the zona reticularis that produce sex hormones. - GOC:tfm - ISBN:0517223651 - @@ -24927,24 +9775,7 @@ radial glial cells acting as neural progenitors throughout life. - A endothelial cell of a lymphatic vessel. The border of the oak leaf-shaped endothelial cell of initial lymphatics are joined by specialized buttons. The discontinuous feature of buttons distinguishes them from zippers in collecting lymphatics, but both types of junctions are composed of proteins typical of adherens junctions and tight junctions found in the endothelium of blood vessels. Buttons seal the sides of flaps of the oak leaf-shaped endothelial cell, leaving open the tips of flaps as routes for fluid entry without disassembly and reformation of intercellular junctions. - tmeehan - 2010-08-24T02:05:28Z - CL:1000421 - BTO:0004167 - FMA:68458 - LEC - lymphatic endothelial cell - cell - endothelial cell of lymphatic vessel - - - - - A endothelial cell of a lymphatic vessel. The border of the oak leaf-shaped endothelial cell of initial lymphatics are joined by specialized buttons. The discontinuous feature of buttons distinguishes them from zippers in collecting lymphatics, but both types of junctions are composed of proteins typical of adherens junctions and tight junctions found in the endothelium of blood vessels. Buttons seal the sides of flaps of the oak leaf-shaped endothelial cell, leaving open the tips of flaps as routes for fluid entry without disassembly and reformation of intercellular junctions. - GOC:tfm - PMID:17846148 - + @@ -24952,26 +9783,7 @@ radial glial cells acting as neural progenitors throughout life. - An endothelial cell of the vascular tree, which includes blood vessels and lymphatic vessels. - tmeehan - 2010-08-24T02:06:40Z - BTO:0001854 - CALOHA:TS-1106 - FMA:67755 - vascular endothelial cell - cubodial endothelial cell of vascular tree - cell - These cells are reportedly CD31-positive, CD34-positive, CD144-positive, TAL1-positive. - endothelial cell of vascular tree - - - - - An endothelial cell of the vascular tree, which includes blood vessels and lymphatic vessels. - GOC:dsd - GOC:tfm - PMID:12768659 - + @@ -24981,22 +9793,7 @@ radial glial cells acting as neural progenitors throughout life. - A sebum secreting cell of the skin that secretes sebum into the hair follicles. - tmeehan - 2010-08-24T09:27:52Z - CL:0002587 - sebocyte - BTO:0004613 - FMA:70953 - cell - acinar cell of sebaceous gland - - - - A sebum secreting cell of the skin that secretes sebum into the hair follicles. - GOC:tfm - @@ -25004,20 +9801,7 @@ radial glial cells acting as neural progenitors throughout life. - A parathyroid chief cell that is actively secreting hormone. Have large Golgi complexes with numerous vesicles and small membrane-bound granules; secretory granules are rare, cytoplasmic glycogen sparse, much of the cytoplasm being occupied by flat sacs of granular endoplasmic reticulum in parallel arrays; in normal humans, inactive chief cells outnumber active chief cells in a ratio of 3-5:1 - tmeehan - 2010-08-24T09:30:15Z - FMA:69082 - cell - active chief cell of parathyroid gland - - - - A parathyroid chief cell that is actively secreting hormone. Have large Golgi complexes with numerous vesicles and small membrane-bound granules; secretory granules are rare, cytoplasmic glycogen sparse, much of the cytoplasm being occupied by flat sacs of granular endoplasmic reticulum in parallel arrays; in normal humans, inactive chief cells outnumber active chief cells in a ratio of 3-5:1 - FMA:0517223651 - GOC:tfm - @@ -25028,19 +9812,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell pyramidal in shape, with their broad ends facing and forming the greater extent of the lining of the main lumen. Secretes glycoproteins associated with mucus. - tmeehan - 2010-08-24T02:15:16Z - FMA:70659 - cell - dark cell of eccrine sweat gland - - - - A cell pyramidal in shape, with their broad ends facing and forming the greater extent of the lining of the main lumen. Secretes glycoproteins associated with mucus. - ISBN:0517223651 - @@ -25048,20 +9820,7 @@ radial glial cells acting as neural progenitors throughout life. - A chief cell that is smaller than light chief cells and has a smaller and darker nucleus and a finely granular cytoplasm with many granules. - tmeehan - 2010-08-24T02:18:36Z - FMA:69080 - cell - dark chief cell of parathyroid cell - - - - A chief cell that is smaller than light chief cells and has a smaller and darker nucleus and a finely granular cytoplasm with many granules. - GOC:tfm - ISBN:0721662544 - @@ -25069,21 +9828,7 @@ radial glial cells acting as neural progenitors throughout life. - An endothelial cell found in capillaries. - tmeehan - 2010-08-24T10:15:00Z - BTO:0004956 - CALOHA:TS-0112 - FMA:67756 - cell - capillary endothelial cell - - - - An endothelial cell found in capillaries. - GOC:tfm - @@ -25092,20 +9837,7 @@ radial glial cells acting as neural progenitors throughout life. - A ciliated columnar cell found in the trachea and bronchus. Vary from low to tall columnar; possesses up to 300 cilia at its surface, interspersed with long irregular microvilli with the cilia varying in length from about 6um in the trachea to about 4um in the terminal bronchioles; driving force of the ciliary current in the bronchial tree. - tmeehan - 2010-08-24T03:38:29Z - FMA:70542 - cell - ciliated columnar cell of tracheobronchial tree - - - - A ciliated columnar cell found in the trachea and bronchus. Vary from low to tall columnar; possesses up to 300 cilia at its surface, interspersed with long irregular microvilli with the cilia varying in length from about 6um in the trachea to about 4um in the terminal bronchioles; driving force of the ciliary current in the bronchial tree. - GOC:tfm - ISBN:0517223651 - @@ -25116,20 +9848,7 @@ radial glial cells acting as neural progenitors throughout life. - A sweat producing cell of eccrine sweat glands. Pyramidal in shape, with its base resting on the basal lamina or myoepitheliocytes, and its microvillus-covered apical plasma membrane line up the intercellular canaliculi. Cell is not stained by hematoxylin or eosin. - tmeehan - 2010-08-24T10:33:02Z - FMA:70658 - cell - clear cell of eccrine sweat gland - - - - A sweat producing cell of eccrine sweat glands. Pyramidal in shape, with its base resting on the basal lamina or myoepitheliocytes, and its microvillus-covered apical plasma membrane line up the intercellular canaliculi. Cell is not stained by hematoxylin or eosin. - GOC:tfm - ISBN:0517223651 - @@ -25137,20 +9856,7 @@ radial glial cells acting as neural progenitors throughout life. - A chief cell of parathyroid glands that does not stain with hematoxylin or eosin. This cell is larger, has a larger nucleus and fewer secretory granules than dark chief cells. - tmeehan - 2010-08-24T10:39:42Z - FMA:69081 - cell - clear chief cell of parathyroid cell - - - - A chief cell of parathyroid glands that does not stain with hematoxylin or eosin. This cell is larger, has a larger nucleus and fewer secretory granules than dark chief cells. - GOC:tfm - ISBN:0618947256 - @@ -25159,22 +9865,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell found within the dental pulp. - tmeehan - 2010-08-24T02:52:09Z - BTO:0000339 - CALOHA:TS-0195 - FMA:87170 - cell - dental pulp cell - - - - A cell found within the dental pulp. - GOC:tfm - PMID:11087820 - @@ -25182,20 +9873,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell of the uterus. - tmeehan - 2010-08-24T10:45:54Z - CL:1000294 - FMA:256161 - cell - epithelial cell of uterus - - - - An epithelial cell of the uterus. - GOC:tfm - @@ -25203,30 +9881,7 @@ radial glial cells acting as neural progenitors throughout life. - Epithelioid macrophage is an activated macrophage that resembles an epithelial cell with finely granular, pale eosinophilic cytoplasm and central, ovoid nucleus (oval or elongate). This cell type is able to merge into one another to form aggregates. The presence of such aggregates may characterize some pathologic conditions, mainly granulomatous inflammation. - tmeehan - 2010-08-24T03:48:30Z - epithelioid cell - FMA:83514 - epithelioid histocyte - epitheloid macrophage - cell - epithelioid macrophage - - - - - Epithelioid macrophage is an activated macrophage that resembles an epithelial cell with finely granular, pale eosinophilic cytoplasm and central, ovoid nucleus (oval or elongate). This cell type is able to merge into one another to form aggregates. The presence of such aggregates may characterize some pathologic conditions, mainly granulomatous inflammation. - MESH:A11.329.372.300 - PMID:12673090 - - - - - epithelioid histocyte - MESH:A11.329.372.300 - PMID:12673090 - + @@ -25234,19 +9889,7 @@ radial glial cells acting as neural progenitors throughout life. - A promyelocyte that is considerably smaller, with more condensed chromatin, and nucleoli are no longer conspicuous. - tmeehan - 2010-08-24T03:07:50Z - FMA:83534 - cell - late promyelocyte - - - - A promyelocyte that is considerably smaller, with more condensed chromatin, and nucleoli are no longer conspicuous. - ISBN:0412046911 - @@ -25255,20 +9898,7 @@ radial glial cells acting as neural progenitors throughout life. - A columnar cell of the cervix uteri. - tmeehan - 2010-08-24T10:47:47Z - FMA:86486 - cell - columnar cell of endocervix - - - - A columnar cell of the cervix uteri. - GOC:tfm - ISBN:0721662544 - @@ -25277,21 +9907,7 @@ radial glial cells acting as neural progenitors throughout life. - The dead keratin-filled squamous cell of the stratum corneum. This cell type lacks a nucleus. - tmeehan - 2010-08-24T10:53:03Z - BTO:0001943 - FMA:68650 - cell - corneocyte - - - - The dead keratin-filled squamous cell of the stratum corneum. This cell type lacks a nucleus. - GOC:tfm - ISBN:068340007X - @@ -25299,20 +9915,7 @@ radial glial cells acting as neural progenitors throughout life. - A promyelocyte with a nucleus that is indented and contains more marginated heterochromatin compared to its precursor cell (myeloblast); cytoplasm is deeply basophilic and contains numerous mitochondria and meandering cysternae of endoplasmic reticulum; largest of the granulocyte lineages. - tmeehan - 2010-08-24T03:07:53Z - FMA:83533 - cell - early promyelocyte - - - - A promyelocyte with a nucleus that is indented and contains more marginated heterochromatin compared to its precursor cell (myeloblast); cytoplasm is deeply basophilic and contains numerous mitochondria and meandering cysternae of endoplasmic reticulum; largest of the granulocyte lineages. - FMA:0412046911 - GOC:tfm - @@ -25320,20 +9923,7 @@ radial glial cells acting as neural progenitors throughout life. - A crenated erythrocyte with 30+ crenations, bumps or spurs that are the result of damage due to age or disease. - tmeehan - 2010-08-24T03:15:21Z - FMA:81099 - burr cell - cell - echinocyte - - - - A crenated erythrocyte with 30+ crenations, bumps or spurs that are the result of damage due to age or disease. - GOC:tfm - @@ -25342,20 +9932,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell type that makes up the highly vascular membrane lining the marrow cavity of long bones. - tmeehan - 2010-08-24T03:33:58Z - FMA:86495 - cell - endosteal cell - - - - A cell type that makes up the highly vascular membrane lining the marrow cavity of long bones. - FMA:0618947256 - GOC:tfm - @@ -25363,20 +9940,7 @@ radial glial cells acting as neural progenitors throughout life. - Epithelial cell found on the external side of the tympanic membrane - tmeehan - 2010-08-25T10:25:31Z - FMA:70558 - cell - external epithelial cell of tympanic membrane - - - - Epithelial cell found on the external side of the tympanic membrane - GOC:tfm - PMID:5686391 - @@ -25384,19 +9948,7 @@ radial glial cells acting as neural progenitors throughout life. - Epithelial cells derived from general body ectoderm and ectoderm placodes. - tmeehan - 2010-08-26T08:31:08Z - FMA:70556 - cell - general ecto-epithelial cell - - - - Epithelial cells derived from general body ectoderm and ectoderm placodes. - GOC:tfm - @@ -25404,18 +9956,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell type found in the basal epithelial layer on the external side of the tympanic membrane. Cell type is flattened with intracellular spaces of variable dimensions. - tmeehan - 2010-08-25T10:28:44Z - cell - basal external epithelial cell of tympanic membrane - - - - A cell type found in the basal epithelial layer on the external side of the tympanic membrane. Cell type is flattened with intracellular spaces of variable dimensions. - PMID:5686391 - @@ -25423,18 +9964,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell type found on the superficial layer of the external side of the tympanic membrane. This cell-type lacks a nucleus. - tmeehan - 2010-08-25T10:28:48Z - cell - superficial external epithelial cell of tympanic membrane - - - - A cell type found on the superficial layer of the external side of the tympanic membrane. This cell-type lacks a nucleus. - PMID:5686391 - @@ -25442,20 +9972,7 @@ radial glial cells acting as neural progenitors throughout life. - An extremely flattened cell type found on the inner side of the tympanic membrane. The surface of this cell type carries sparse pleomorphic microvilli that are more common near the junctional zones. - tmeehan - 2010-08-25T10:49:46Z - FMA:70626 - cell - internal epithelial cell of tympanic membrane - - - - An extremely flattened cell type found on the inner side of the tympanic membrane. The surface of this cell type carries sparse pleomorphic microvilli that are more common near the junctional zones. - FMA:5686391 - GOC:tfm - @@ -25463,21 +9980,7 @@ radial glial cells acting as neural progenitors throughout life. - A rod-shpaed cell that forms a single row adjacent to and supporting the inner hair cells. - tmeehan - 2010-08-25T11:05:21Z - FMA:75722 - FMA:75726 - cell - internal pillar cell of cochlea - - - - A rod-shpaed cell that forms a single row adjacent to and supporting the inner hair cells. - GOC:tfm - http://www.theodora.com/anatomy/the_internal_ear_or_labyrinth.html - @@ -25485,20 +9988,7 @@ radial glial cells acting as neural progenitors throughout life. - A rod-shaped cell found in 3 or 4 rows that lie adjacent to and support the outer hair cells. - tmeehan - 2010-08-25T11:05:23Z - FMA:75727 - cell - external pillar cell of cochlea - - - - A rod-shaped cell found in 3 or 4 rows that lie adjacent to and support the outer hair cells. - GOC:tfm - http://www.theodora.com/anatomy/the_internal_ear_or_labyrinth.html - @@ -25506,20 +9996,7 @@ radial glial cells acting as neural progenitors throughout life. - A supporting cell that is attached to the basement membrane and forms rows that support the hair cells. - tmeehan - 2010-08-25T01:29:07Z - FMA:79800 - cell - phalangeal cell - - - - A supporting cell that is attached to the basement membrane and forms rows that support the hair cells. - GOC:tfm - ISBN:0618947256 - @@ -25528,23 +10005,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell that remains from the disintegration of the epithelial root sheath involved in the development of teeth. - tmeehan - 2010-08-26T08:51:27Z - FMA:62987 - epithelial cell rests of Malassez - epithelial debris of Malassez - cell - epithelial cell of Malassez - - - - - An epithelial cell that remains from the disintegration of the epithelial root sheath involved in the development of teeth. - GOC:tfm - ISBN:0517223651 - ISBN:0815129521 - + @@ -25553,20 +10014,7 @@ radial glial cells acting as neural progenitors throughout life. - A specialized cell involved in sensory perception of smell. - tmeehan - 2010-08-26T01:47:13Z - FMA:67870 - cell - olfactory epithelial cell - - - - A specialized cell involved in sensory perception of smell. - GOC:tfm - PMID:7143026 - @@ -25574,20 +10022,7 @@ radial glial cells acting as neural progenitors throughout life. - A border cell is a slender columnar cell on the medial portion of the basilar membrane. - tmeehan - 2010-08-25T01:47:12Z - FMA:79798 - cell - border cell of cochlea - - - - A border cell is a slender columnar cell on the medial portion of the basilar membrane. - FMA:0412046911 - GOC:tfm - @@ -25596,22 +10031,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell located on the basal lamina of the olfactory epithelium. - tmeehan - 2010-08-26T01:58:54Z - CL:1000395 - horizontal basal call - FMA:62303 - cell - basal cell of olfactory epithelium - - - - An epithelial cell located on the basal lamina of the olfactory epithelium. - GOC:tfm - PMID:7143026 - @@ -25621,19 +10041,7 @@ radial glial cells acting as neural progenitors throughout life. - A keratinized cell located in the hard palate or gingiva. - tmeehan - 2010-08-26T02:51:30Z - cell - keratinized cell of the oral mucosa - - - - A keratinized cell located in the hard palate or gingiva. - GOC:tfm - PMID:12014572 - @@ -25641,21 +10049,7 @@ radial glial cells acting as neural progenitors throughout life. - A rounded or elliptical epithelial cell, with pale-staining open face nucleus and pale cytoplasm rich in free ribosomes and clusters of centrioles; form a distinct basal zone spaced slightly from the basal surface of the epithelium. - tmeehan - 2010-08-26T01:59:18Z - FMA:67874 - blastema cell of olfactory epithelium - cell - globose cell of olfactory epithelium - - - - A rounded or elliptical epithelial cell, with pale-staining open face nucleus and pale cytoplasm rich in free ribosomes and clusters of centrioles; form a distinct basal zone spaced slightly from the basal surface of the epithelium. - GOC:tfm - PMID:17468753 - @@ -25663,22 +10057,7 @@ radial glial cells acting as neural progenitors throughout life. - A long, spindle-shaped supporting cells arranged in parallel rows that secretes components of the tectorial membrane and potassium ions into the endolymph. - tmeehan - 2010-08-25T02:02:48Z - FMA:79797 - interdental cell - cell - interdental cell of cochlea - - - - A long, spindle-shaped supporting cells arranged in parallel rows that secretes components of the tectorial membrane and potassium ions into the endolymph. - GOC:tfm - MP:0004482 - PMID:2111803 - @@ -25690,25 +10069,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell that is a specialized type of pericyte providing structural support for the capillary loops of kidney. A flat, elongated cell with extensive fine cytoplasmic processes found outside the kidney glomerulus near the macula densa and bound laterally by afferent and efferent arterioles. Being phagocytic, this cell participates in the continuous turnover of the basal lamina by removing its outer portion containing residues of filtration, while the lamina is renewed on its inner surface by the endothelial cells. - tmeehan - 2010-08-25T02:20:55Z - FMA:84143 - KUPO:0001033 - Goormaghtigh cell - polar cushion cells - cell - lacis cell - extraglomerular mesangial cell - - - - - A cell that is a specialized type of pericyte providing structural support for the capillary loops of kidney. A flat, elongated cell with extensive fine cytoplasmic processes found outside the kidney glomerulus near the macula densa and bound laterally by afferent and efferent arterioles. Being phagocytic, this cell participates in the continuous turnover of the basal lamina by removing its outer portion containing residues of filtration, while the lamina is renewed on its inner surface by the endothelial cells. - GOC:tfm - ISBN:0412046911 - http:/www.copewithcytokines.de/cope.cgi?key=Lacis%20cells - + @@ -25716,20 +10077,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell within the follicle of an ovary. - tmeehan - 2010-08-25T03:01:27Z - EMAPA:31247 - FMA:70589 - cell - follicular cell of ovary - - - - A cell within the follicle of an ovary. - GOC:tfm - @@ -25737,19 +10085,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell within the primary follicle of the ovary. - tmeehan - 2010-08-25T03:03:42Z - FMA:70590 - cell - primary follicular cell of ovary - - - - A cell within the primary follicle of the ovary. - GOC:tfm - @@ -25757,19 +10093,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell of a secondary follicile within the ovary. - tmeehan - 2010-08-25T03:03:48Z - FMA:70591 - cell - secondary follicular cell of ovary - - - - A cell of a secondary follicile within the ovary. - GOC:tfm - @@ -25778,21 +10102,9 @@ radial glial cells acting as neural progenitors throughout life. + - A supporting cell of the anterior pituitary gland involved in trophic and catabolic processes; expresses a broad spectrum of cytokeratins indicative of their epithelial nature. - tmeehan - 2010-08-25T03:10:10Z - FMA:83102 - folliculostellate cell of pars anterior of adenohypophysis - cell - folliculostellate cell of pars distalis of adenohypophysis - - - - A supporting cell of the anterior pituitary gland involved in trophic and catabolic processes; expresses a broad spectrum of cytokeratins indicative of their epithelial nature. - GOC:tfm - @@ -25800,20 +10112,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell found in the lining of the stomach. - tmeehan - 2010-08-25T03:22:08Z - CL:1000399 - FMA:62948 - cell - epithelial cell of stomach - - - - An epithelial cell found in the lining of the stomach. - GOC:tfm - @@ -25821,20 +10120,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell within one of the pits in the embryonic gastric mucosa from which the gastric glands develop . - tmeehan - 2010-08-25T03:23:22Z - FMA:86552 - cell - foveolar cell of stomach - - - - An epithelial cell within one of the pits in the embryonic gastric mucosa from which the gastric glands develop . - GOC:tfm - http://www.merriam-webster.com/medical/foveolar - @@ -25842,20 +10128,7 @@ radial glial cells acting as neural progenitors throughout life. - A mucous cell in the epithelium of the stomach. - tmeehan - 2010-08-25T03:38:51Z - CL:1000404 - FMA:63464 - cell - mucous cell of stomach - - - - A mucous cell in the epithelium of the stomach. - GOC:tfm - @@ -25865,21 +10138,7 @@ radial glial cells acting as neural progenitors throughout life. - A neck cell that secretes mucus within the stomach. Its products are distinct histochemically from those of the surface mucous cells of stomach. - tmeehan - 2010-08-25T03:41:30Z - CL:1000401 - FMA:62954 - cell - mucus neck cell of gastric gland - - - - A neck cell that secretes mucus within the stomach. Its products are distinct histochemically from those of the surface mucous cells of stomach. - GOC:tfm - ISBN:0517223651 - @@ -25888,20 +10147,7 @@ radial glial cells acting as neural progenitors throughout life. - A simple columnar cell that populates the entire luminal surface including the gastric pits. This cell types secrete mucus to form a thick protective, lubricant layer over the gastric wall. - tmeehan - 2010-08-25T03:45:10Z - FMA:62949 - cell - surface mucosal cell of stomach - - - - A simple columnar cell that populates the entire luminal surface including the gastric pits. This cell types secrete mucus to form a thick protective, lubricant layer over the gastric wall. - GOC:tfm - ISBN:0517223651 - @@ -25911,21 +10157,7 @@ radial glial cells acting as neural progenitors throughout life. - A stomach epithelial cell that is olumnar in form with a few short apical microvilli; relatively undifferentiated mitotic cell from which other types of gland are derived; few in number, situated in the isthmus region of the gland and base of the gastric pit. - tmeehan - 2010-08-25T03:57:08Z - CL:1000400 - FMA:62953 - cell - stem cell of gastric gland - - - - A stomach epithelial cell that is olumnar in form with a few short apical microvilli; relatively undifferentiated mitotic cell from which other types of gland are derived; few in number, situated in the isthmus region of the gland and base of the gastric pit. - GOC:tfm - ISBN:0517223651 - @@ -25933,22 +10165,7 @@ radial glial cells acting as neural progenitors throughout life. - A flat or angular epithelial cell with condensed nuclei and darkly staining cytoplasm containing numerous intermediate filaments inserted into desmosomes contacting surrounding supporting cells; lie in contact with the basal lamina of olfactory epithelium. - tmeehan - 2010-08-26T01:59:22Z - FMA:62304 - horizontal basal cells - cell - basal proper cell of olfactory epithelium - - - - A flat or angular epithelial cell with condensed nuclei and darkly staining cytoplasm containing numerous intermediate filaments inserted into desmosomes contacting surrounding supporting cells; lie in contact with the basal lamina of olfactory epithelium. - GOC:tfm - PMID:0517223651 - PMID:11891623 - @@ -25958,21 +10175,7 @@ radial glial cells acting as neural progenitors throughout life. - A basally situated, mitotically active, columnar-shaped keratinocyte attached to the basement membrane. - tmeehan - 2010-08-26T03:12:49Z - CL:1000439 - FMA:70571 - cell - basal cell of epidermis - - - - A basally situated, mitotically active, columnar-shaped keratinocyte attached to the basement membrane. - GOC:tfm - ISBN:0517223651 - @@ -25982,21 +10185,7 @@ radial glial cells acting as neural progenitors throughout life. - An endothelial cell found in the glomerulus of the kidney. This cell is flattened, highly fenestrated, and plays a vital role in the formation of glomerular ultrafiltrate. - tmeehan - 2010-08-26T10:59:44Z - BTO:0004632 - FMA:70970 - cell - glomerular endothelial cell - - - - An endothelial cell found in the glomerulus of the kidney. This cell is flattened, highly fenestrated, and plays a vital role in the formation of glomerular ultrafiltrate. - GOC:tfm - PMID:15840009 - @@ -26004,19 +10193,7 @@ radial glial cells acting as neural progenitors throughout life. - A keratinocyte of the epidermis that is characterized by containing granules of keratohyalin and lamellar granules. - tmeehan - 2010-08-26T03:19:00Z - FMA:70543 - cell - granular cell of epidermis - - - - A keratinocyte of the epidermis that is characterized by containing granules of keratohyalin and lamellar granules. - ISBN:1416031855 - @@ -26024,20 +10201,7 @@ radial glial cells acting as neural progenitors throughout life. - A flat keratinocyte immediately below the cornified layer. - tmeehan - 2010-08-26T03:37:02Z - FMA:86925 - cell - squamous cell of epidermis - - - - A flat keratinocyte immediately below the cornified layer. - GOC:tfm - ISBN:0517223651 - @@ -26045,19 +10209,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell involved in the formation of a granulocyte. - tmeehan - 2010-08-30T12:54:27Z - FMA:83519 - cell - granulocytopoietic cell - - - - A cell involved in the formation of a granulocyte. - GOC:tfm - @@ -26066,21 +10218,7 @@ radial glial cells acting as neural progenitors throughout life. - A eosinophil precursor in the granulocytic series, being a cell intermediate in development between a myelocyte and a band form cell. The nucleus becomes indented where the indentation is smaller than half the distance to the farthest nuclear margin; chromatin becomes coarse and clumped; specific granules predominate while primary granules are rare. - tmeehan - 2010-08-30T01:08:15Z - FMA:83541 - cell - metamyelocyte - - - - A eosinophil precursor in the granulocytic series, being a cell intermediate in development between a myelocyte and a band form cell. The nucleus becomes indented where the indentation is smaller than half the distance to the farthest nuclear margin; chromatin becomes coarse and clumped; specific granules predominate while primary granules are rare. - GOC:tfm - ISBN:0721601464 - http://en.wikipedia.org/wiki/Metamyelocyte - @@ -26089,22 +10227,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell type that is the first of the maturation stages of the granulocytic leukocytes normally found in the bone marrow. Granules are seen in the cytoplasm. The nuclear material of the myelocyte is denser than that of the myeloblast but lacks a definable membrane. The cell is flat and contains increasing numbers of granules as maturation progresses. - tmeehan - 2010-08-30T01:08:19Z - BTO:0000734 - FMA:83525 - cell - myelocyte - - - - A cell type that is the first of the maturation stages of the granulocytic leukocytes normally found in the bone marrow. Granules are seen in the cytoplasm. The nuclear material of the myelocyte is denser than that of the myeloblast but lacks a definable membrane. The cell is flat and contains increasing numbers of granules as maturation progresses. - GOC:tfm - ISBN:0323052908 - http://en.wikipedia.org/wiki/Myelocyte - @@ -26112,19 +10235,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell involved in the formation of a monocyte (monopoiesis). - tmeehan - 2010-08-30T01:27:48Z - FMA:83552 - cell - monopoietic cell - - - - A cell involved in the formation of a monocyte (monopoiesis). - GOC:tfm - @@ -26132,19 +10243,7 @@ radial glial cells acting as neural progenitors throughout life. - A stem cell that can give rise to the cells of the liver. - tmeehan - 2010-08-30T02:00:42Z - FMA:86577 - cell - hepatic stem cell - - - - A stem cell that can give rise to the cells of the liver. - GOC:tfm - @@ -26152,22 +10251,7 @@ radial glial cells acting as neural progenitors throughout life. - A transient hepatic stem cell observed after liver injury with a high nuclear to cytoplasm ratio that can differentiate into mature hepatocytes and bile duct cells. Arises from more than one tissue. - tmeehan - 2010-08-30T02:01:49Z - CL:1000036 - BTO:0004270 - FMA:86576 - hepatic oval cell - cell - hepatic oval stem cell - - - - A transient hepatic stem cell observed after liver injury with a high nuclear to cytoplasm ratio that can differentiate into mature hepatocytes and bile duct cells. Arises from more than one tissue. - PMID:17901986 - @@ -26175,19 +10259,7 @@ radial glial cells acting as neural progenitors throughout life. - A parathyroid chief cell that is not actively secreting hormone. Contains small Golgi complexes with only a few grouped vesicles and membrane-bound secretory granules; glycogen and many lipofuscin granules abound but sacs of granular endoplasmic reticulum are rare and dispersed. In normal humans, inactive chief cells out number active chief cells in a ratio of 3-5:1. - tmeehan - 2010-09-02T11:14:01Z - cell - inactive chief cell of parathyoid gland - - - - A parathyroid chief cell that is not actively secreting hormone. Contains small Golgi complexes with only a few grouped vesicles and membrane-bound secretory granules; glycogen and many lipofuscin granules abound but sacs of granular endoplasmic reticulum are rare and dispersed. In normal humans, inactive chief cells out number active chief cells in a ratio of 3-5:1. - GOC:tfm - ISBN:0517223651 - @@ -26195,22 +10267,7 @@ radial glial cells acting as neural progenitors throughout life. - A large epithelial cell with an extremely acidophilic and granular cytoplasm, containing vast numbers of mitochondria; such cells may undergo neoplastic transformation. From the Greek word onkos meaning swelling, this cell type is found in parathyroid, salivary and thyroid glands. - tmeehan - 2010-09-02T11:26:49Z - FMA:67606 - oxyphil - cell - oncocyte - - - - A large epithelial cell with an extremely acidophilic and granular cytoplasm, containing vast numbers of mitochondria; such cells may undergo neoplastic transformation. From the Greek word onkos meaning swelling, this cell type is found in parathyroid, salivary and thyroid glands. - GOC:tfm - ISBN:0721662544 - PMID:20013317 - @@ -26219,19 +10276,7 @@ radial glial cells acting as neural progenitors throughout life. - An oncocyte located in the parathyroid gland. - tmeehan - 2010-09-02T11:33:23Z - FMA:69084 - cell - oxyphil cell of parathyroid gland - - - - An oncocyte located in the parathyroid gland. - PMID:20013317 - @@ -26240,22 +10285,7 @@ radial glial cells acting as neural progenitors throughout life. - An oncocyte located in the thyroid. - tmeehan - 2010-09-02T11:33:26Z - FMA:87169 - Askanazy cells - Hurthle cells - cell - oxyphil cell of thyroid - - - - An oncocyte located in the thyroid. - GOC:tfm - PMID:20013317 - @@ -26263,19 +10293,7 @@ radial glial cells acting as neural progenitors throughout life. - A renal intercalated cell that secretes base and reabsorbs acid in the coritcal collecting duct to mantain acid/base balance. - tmeehan - 2010-09-02T01:43:55Z - cell - renal beta-intercalated cell - - - - A renal intercalated cell that secretes base and reabsorbs acid in the coritcal collecting duct to mantain acid/base balance. - GOC:tfm - PMID:11781354 - @@ -26283,20 +10301,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell of the tracheobronchial tree. - tmeehan - 2010-09-02T02:09:14Z - CL:1000407 - FMA:66816 - cell - epithelial cell of tracheobronchial tree - - - - An epithelial cell of the tracheobronchial tree. - GOC:tfm - @@ -26305,21 +10310,7 @@ radial glial cells acting as neural progenitors throughout life. - Brush cell found in the epithelial layer of the colon. - tmeehan - 2010-09-02T02:20:50Z - CL:1000387 - FMA:263222 - cell - Brush cells are a distinct cell type from brush border cell-types. - Brush cell of epithelium proper of large intestine - - - - Brush cell found in the epithelial layer of the colon. - GOC:tfm - @@ -26327,25 +10318,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell type found in the gastrointestinal and respiratory tracts that is characterized by the presence of a tuft of blunt, squat microvilli (120-140 per cell). Function of this cell type is not known. - tmeehan - 2010-09-02T02:28:53Z - FMA:67978 - caveolated cell - fibrillovesicular cell - multivesicular cell - tuft cell - cell - brush cell - - - - - A cell type found in the gastrointestinal and respiratory tracts that is characterized by the presence of a tuft of blunt, squat microvilli (120-140 per cell). Function of this cell type is not known. - GOC:tfm - ISBN:0517223651 - PMID:15817800 - + @@ -26354,20 +10327,7 @@ radial glial cells acting as neural progenitors throughout life. - A brush cell found in the epithelium of lobular bronchiole. - tmeehan - 2010-09-02T02:38:34Z - CL:1000386 - FMA:263220 - cell - brush cell of lobular bronchiole - - - - A brush cell found in the epithelium of lobular bronchiole. - GOC:tfm - @@ -26375,20 +10335,7 @@ radial glial cells acting as neural progenitors throughout life. - A brush cell of the epithelium in the terminal bronchiole. - tmeehan - 2010-09-02T02:38:36Z - CL:1000390 - FMA:263228 - cell - brush cell of terminal bronchiole - - - - A brush cell of the epithelium in the terminal bronchiole. - GOC:tfm - @@ -26397,20 +10344,7 @@ radial glial cells acting as neural progenitors throughout life. - Brush cell of the epithelium in the trachea. - tmeehan - 2010-09-02T02:38:37Z - CL:1000388 - FMA:263224 - cell - brush cell of trachea - - - - Brush cell of the epithelium in the trachea. - GOC:tfm - @@ -26419,20 +10353,7 @@ radial glial cells acting as neural progenitors throughout life. - A brush cell found in the epithelium of bronchus. - tmeehan - 2010-09-02T02:38:42Z - CL:1000389 - FMA:263226 - cell - brush cell of bronchus - - - - A brush cell found in the epithelium of bronchus. - GOC:tfm - @@ -26440,21 +10361,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell present in the trachea and bronchi; columnar in shape; generally lack cilia; immature forms of ciliated or secretory cells which have been formed from stem cells. - tmeehan - 2010-09-02T02:53:59Z - FMA:69060 - undifferentiated columnar cell of tracheobronchial tree - cell - intermediate epitheliocyte - - - - An epithelial cell present in the trachea and bronchi; columnar in shape; generally lack cilia; immature forms of ciliated or secretory cells which have been formed from stem cells. - GOC:tfm - ISBN:0517223651 - @@ -26462,22 +10369,7 @@ radial glial cells acting as neural progenitors throughout life. - A slow muscle cell that contains high levels of myoglobin and oxygen storing proteins giving the cell a red appearance. - tmeehan - 2010-09-02T03:20:03Z - FMA:84448 - oxidative muscle fiber - red muscle fiber - cell - red muscle cell - - - - A slow muscle cell that contains high levels of myoglobin and oxygen storing proteins giving the cell a red appearance. - GOC:tfm - ISBN:0517223651 - @@ -26486,49 +10378,7 @@ radial glial cells acting as neural progenitors throughout life. - A slow muscle cell that has large amounts of myoglobin, stores energy as triglycerides, generates ATP by the oxidative method and is resistant to fatigue. - tmeehan - 2010-09-02T03:24:05Z - BTO:0001812 - CALOHA:TS-0940 - FMA:84413 - MESH:A02.633.565.700 - slow twitch fiber - slow twitch muscle cell - type 1 muscle cell - type 1 muscle fiber - type I muscle fiber - cell - intermediate muscle fiber - slow twitch muscle fiber - slow-twitch muscle fiber - type I muscle cell - - - - - A slow muscle cell that has large amounts of myoglobin, stores energy as triglycerides, generates ATP by the oxidative method and is resistant to fatigue. - GOC:tfm - ISBN:0517223651 - - - - - intermediate muscle fiber - MESH:A02.633.565.700 - - - - - slow twitch muscle fiber - MESH:A02.633.565.700 - - - - - slow-twitch muscle fiber - MESH:A02.633.565.700 - + @@ -26536,23 +10386,7 @@ radial glial cells acting as neural progenitors throughout life. - A fast muscle fiber cell that stores energy in the form of glycogen and creatine phosphate. - tmeehan - 2010-09-02T03:28:45Z - BTO:0001813 - FMA:84414 - type 2 muscle cell - type 2 muscle fiber - type II muscle fiber - cell - type II muscle cell - - - - - A fast muscle fiber cell that stores energy in the form of glycogen and creatine phosphate. - GOC:tfm - + @@ -26560,20 +10394,7 @@ radial glial cells acting as neural progenitors throughout life. - A muscle cell with low content of myoglobin and other oxygen storing proteins. This muscle cell has a white appearance. - tmeehan - 2010-09-02T03:28:48Z - FMA:84449 - cell - white muscle cell - - - - A muscle cell with low content of myoglobin and other oxygen storing proteins. This muscle cell has a white appearance. - GOC:tfm - ISBN:0517223651 - @@ -26582,25 +10403,7 @@ radial glial cells acting as neural progenitors throughout life. - A type II muscle cell that contains large amounts of myoglobin, has many mitochondria and very many blood capillaries. Type II A cells are red, have a very high capacity for generating ATP by oxidative metabolic processes, split ATP at a very rapid rate, have a fast contraction velocity and are resistant to fatigue. - tmeehan - 2010-09-02T03:31:38Z - BTO:0001813 - FMA:84415 - fast twitch A - fatigue resistant fast twitch muscle cell - type 2a muscle cell - type 2a muscle fiber - type IIa muscle fiber - cell - type IIa muscle cell - - - - - A type II muscle cell that contains large amounts of myoglobin, has many mitochondria and very many blood capillaries. Type II A cells are red, have a very high capacity for generating ATP by oxidative metabolic processes, split ATP at a very rapid rate, have a fast contraction velocity and are resistant to fatigue. - GOC:tfm - + @@ -26609,24 +10412,7 @@ radial glial cells acting as neural progenitors throughout life. - A type II muscle cell that contains a low content of myoglobin, relatively few mitochondria, relatively few blood capillaries and large amounts of glycogen. Type II B fibres are white, geared to generate ATP by anaerobic metabolic processes, not able to supply skeletal muscle fibres continuously with sufficient ATP, fatigue easily, split ATP at a fast rate and have a fast contraction velocity. - tmeehan - 2010-09-02T03:31:42Z - FMA:84416 - type 2b muscle cell - type 2b muscle fiber - type IIb muscle fiber - cell - type IIb muscle cell - - - - - A type II muscle cell that contains a low content of myoglobin, relatively few mitochondria, relatively few blood capillaries and large amounts of glycogen. Type II B fibres are white, geared to generate ATP by anaerobic metabolic processes, not able to supply skeletal muscle fibres continuously with sufficient ATP, fatigue easily, split ATP at a fast rate and have a fast contraction velocity. - GOC:tfm - ISBN:0517223651 - http://en.wikipedia.org/wiki/Skeletal_muscle - + @@ -26634,19 +10420,7 @@ radial glial cells acting as neural progenitors throughout life. - An intermediate muscle cell that has characteristics of both fast and slow muscle cells. - tmeehan - 2010-09-02T03:51:17Z - FMA:84450 - cell - intermediate muscle cell - - - - An intermediate muscle cell that has characteristics of both fast and slow muscle cells. - GOC:tfm - @@ -26654,21 +10428,7 @@ radial glial cells acting as neural progenitors throughout life. - A trophoblast that leaves the placenta and invades the endometrium and myometrium. This cell type is crucial in increasing blood flow to the fetus. - tmeehan - 2010-09-02T04:04:36Z - BTO:0002366 - FMA:86564 - cell - intermediate trophoblast cell - - - - A trophoblast that leaves the placenta and invades the endometrium and myometrium. This cell type is crucial in increasing blood flow to the fetus. - GOC:tfm - http://www.med.yale.edu/obgyn/kliman/placenta/articles/EOR_Placenta/Trophtoplacenta.html - @@ -26676,22 +10436,7 @@ radial glial cells acting as neural progenitors throughout life. - A double negative thymocyte that has a T cell receptor consisting of a gamma chain that has as part a Vgamma3 segment, and a delta chain. This cell type is CD4- negative, CD8-negative and CD24-positive. This cell-type is found in the fetal thymus with highest numbers occurring at E17-E18. - tmeehan - 2010-10-07T01:58:00Z - immature DEC precursor - immature DETC precursor - cell - NOTE: currently variable immune gene segments are not represented in the OBO Foundry. Cross-product definitions were not made as a result. Also, there are three different nomenclatures for the variable gamma segments. - immature dendritic epithelial T cell precursor - - - - A double negative thymocyte that has a T cell receptor consisting of a gamma chain that has as part a Vgamma3 segment, and a delta chain. This cell type is CD4- negative, CD8-negative and CD24-positive. This cell-type is found in the fetal thymus with highest numbers occurring at E17-E18. - GOC:tfm - http://www.immgen.org - @@ -26699,19 +10444,7 @@ radial glial cells acting as neural progenitors throughout life. - A trophoblast found at the junction of the placenta. This cell type makes a unique fibronectin-trophouteronectin junction that helps mediate attachment of the placenta to the uterus. This cell type is also found junction of the chorion layer of the external membranes and the decidua. - tmeehan - 2010-09-02T04:14:28Z - cell - anchoring trophoblast - - - - A trophoblast found at the junction of the placenta. This cell type makes a unique fibronectin-trophouteronectin junction that helps mediate attachment of the placenta to the uterus. This cell type is also found junction of the chorion layer of the external membranes and the decidua. - GOC:tfm - http://www.med.yale.edu/obgyn/kliman/placenta/articles/EOR_Placenta/Trophtoplacenta.html - @@ -26719,20 +10452,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell located between the pinealocytes. - tmeehan - 2010-09-02T04:28:41Z - FMA:86575 - cell - interstitial cell of pineal gland - - - - A cell located between the pinealocytes. - GOC:tfm - ISBN:0517223651 - @@ -26741,20 +10461,7 @@ radial glial cells acting as neural progenitors throughout life. - A squamous cell that has keratin in the esophagus. - tmeehan - 2010-09-07T10:11:06Z - FMA:86549 - cell - keratinized squamous cell of esophagus - - - - A squamous cell that has keratin in the esophagus. - GOC:tfm - PMID:11694559 - @@ -26764,20 +10471,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell comprising the transparent, biconvex body separating the posterior chamber and vitreous body, and constituting part of the refracting mechanism of the mammalian eye. - tmeehan - 2010-09-07T10:38:03Z - FMA:70950 - cell - vertebrate lens cell - - - - A cell comprising the transparent, biconvex body separating the posterior chamber and vitreous body, and constituting part of the refracting mechanism of the mammalian eye. - GOC:tfm - ISBN:0721662544 - @@ -26785,20 +10479,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell of the transparent layer of simple cuboidal epithelium over the anterior surface of the lens; transform into lens fiber(s). - tmeehan - 2010-09-07T10:45:45Z - FMA:63181 - cell - anterior lens cell - - - - A cell of the transparent layer of simple cuboidal epithelium over the anterior surface of the lens; transform into lens fiber(s). - GOC:tfm - ISBN:0517223651 - @@ -26807,21 +10488,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell of the cuboidal epithelium that covers the lens. The cells of the lens epithelium regulate most of the homeostatic functions of the lens. As ions, nutrients, and liquid enter the lens from the aqueous humor, Na+/K+ ATPase pumps in the lens epithelial cells pump ions out of the lens to maintain appropriate lens osmolarity and volume, with equatorially positioned lens epithelium cells contributing most to this current. The activity of the Na+/K+ ATPases keeps water and current flowing through the lens from the poles and exiting through the equatorial regions. The cells of the lens epithelium also serve as the progenitors for new lens fibers. It constantly lays down fibers in the embryo, fetus, infant, and adult, and continues to lay down fibers for lifelong growth. - tmeehan - 2010-09-07T10:45:47Z - FMA:67559 - cell - lens epithelial cell - - - - A cell of the cuboidal epithelium that covers the lens. The cells of the lens epithelium regulate most of the homeostatic functions of the lens. As ions, nutrients, and liquid enter the lens from the aqueous humor, Na+/K+ ATPase pumps in the lens epithelial cells pump ions out of the lens to maintain appropriate lens osmolarity and volume, with equatorially positioned lens epithelium cells contributing most to this current. The activity of the Na+/K+ ATPases keeps water and current flowing through the lens from the poles and exiting through the equatorial regions. The cells of the lens epithelium also serve as the progenitors for new lens fibers. It constantly lays down fibers in the embryo, fetus, infant, and adult, and continues to lay down fibers for lifelong growth. - GOC:tfm - ISBN:0721662544 - http://en.wikipedia.org/wiki/Lens_%28anatomy%29#Lens_epithelium - @@ -26829,20 +10496,7 @@ radial glial cells acting as neural progenitors throughout life. - A lens fiber cell that develops from primary lens fiber; located towards the center of lens; cell organelles are normally degraded or in the process of being degraded. - tmeehan - 2010-09-07T10:53:39Z - secondary lens fibre - cell - secondary lens fiber - - - - A lens fiber cell that develops from primary lens fiber; located towards the center of lens; cell organelles are normally degraded or in the process of being degraded. - GOC:tfm - ISBN:0517223651 - @@ -26850,20 +10504,7 @@ radial glial cells acting as neural progenitors throughout life. - A secondary lens fiber cell that lacks a nucleus. - tmeehan - 2010-09-07T11:15:23Z - FMA:67561 - non-nucleated secondary lens fibre - cell - non-nucleated secondary lens fiber - - - - A secondary lens fiber cell that lacks a nucleus. - GOC:tfm - @@ -26871,20 +10512,7 @@ radial glial cells acting as neural progenitors throughout life. - A secondary fiber cell that contains a nucleus. - tmeehan - 2010-09-07T11:15:26Z - FMA:70949 - nucleated secondary lens fibre - cell - nucleated secondary lens fiber - - - - A secondary fiber cell that contains a nucleus. - GOC:tfm - @@ -26892,21 +10520,7 @@ radial glial cells acting as neural progenitors throughout life. - An elongating cell that rapidly obliterates the lumen of the lens vesicle. Subsequently, differentiation of this cell type at the lens equator leads to the formation of secondary fiber cells that come to overlie the primary fibers. - tmeehan - 2010-09-07T11:19:01Z - FMA:70613 - primary lens fibre - cell - primary lens fiber - - - - An elongating cell that rapidly obliterates the lumen of the lens vesicle. Subsequently, differentiation of this cell type at the lens equator leads to the formation of secondary fiber cells that come to overlie the primary fibers. - GOC:tfm - PMID:10711704 - @@ -26914,20 +10528,7 @@ radial glial cells acting as neural progenitors throughout life. - A chief cell that is bigger than dark chief cells and has a larger and lighter nucleus and a cytoplasm with few granules. - tmeehan - 2010-09-07T11:46:54Z - FMA:69079 - cell - light chief cell of parathyroid gland - - - - A chief cell that is bigger than dark chief cells and has a larger and lighter nucleus and a cytoplasm with few granules. - GOC:tfm - ISBN:0721662544 - @@ -26935,23 +10536,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell of the prostate. - tmeehan - 2010-09-07T01:49:29Z - CL:1000295 - CL:1000408 - FMA:256163 - FMA:66817 - prostate epithelial cell - cell - epithelial cell of prostate - - - - - An epithelial cell of the prostate. - GOC:tfm - + @@ -26960,27 +10545,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell of prostatic duct. - tmeehan - 2010-09-07T01:55:51Z - CL:1000462 - FMA:74224 - ductal epithelial cell of prostate - cell - epithelial cell of prostatic duct - - - - - An epithelial cell of prostatic duct. - GOC:tfm - - - - - ductal epithelial cell of prostate - FMA:74224 - + @@ -26988,28 +10553,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell of the prostatic acinus. - tmeehan - 2010-09-07T01:55:53Z - CL:1000461 - FMA:74223 - acinar epithelial cell of prostate - cell - epithelial cell of prostatic acinus - - - - - An epithelial cell of the prostatic acinus. - GOC:tfm - PMCID:PMC2673349 - - - - - acinar epithelial cell of prostate - FMA:74223 - + @@ -27018,27 +10562,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell of the basal layer of the epithelium in the prostatic acinus. - tmeehan - 2010-09-07T01:59:08Z - CL:1000464 - FMA:74265 - basal epithelial cell of prostatic acinus - cell - basal cell of prostatic acinus - - - - - A cell of the basal layer of the epithelium in the prostatic acinus. - GOC:tfm - - - - - basal epithelial cell of prostatic acinus - FMA:74265 - + @@ -27047,19 +10571,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell of the luminal layer of the epithelium in the prostatic acinus. - tmeehan - 2010-09-07T01:59:10Z - FMA:74266 - cell - luminal cell of prostatic acinus - - - - A cell of the luminal layer of the epithelium in the prostatic acinus. - GOC:tfm - @@ -27068,21 +10580,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell that constitutes the basal layer of epithelium in the prostatic duct. - tmeehan - 2010-09-07T01:59:12Z - CL:1000463 - FMA:74226 - cell - basal epithelial cell of prostatic duct - - - - A cell that constitutes the basal layer of epithelium in the prostatic duct. - GOC:tfm - PMID:15226377 - @@ -27091,19 +10589,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell that constitutes the luminal layer of epithelium of prostatic duct. - tmeehan - 2010-09-07T01:59:16Z - FMA:74225 - cell - luminal epithelial cell of prostatic duct - - - - A cell that constitutes the luminal layer of epithelium of prostatic duct. - GOC:tfm - @@ -27111,30 +10597,7 @@ radial glial cells acting as neural progenitors throughout life. - A primordial germ cell that is destined to become a male germ cell. - tmeehan - 2010-09-07T02:11:13Z - EHDAA2:0001053 - EMAPA:18686 - FMA:84771 - VHOG:0000662 - male primordial germ cell - testis primordial germ cell - cell - male gonocyte - - - - - A primordial germ cell that is destined to become a male germ cell. - GOC:tfm - - - - - testis primordial germ cell - VHOG:0000662 - + @@ -27142,37 +10605,7 @@ radial glial cells acting as neural progenitors throughout life. - A primordial cell from which an oocyte (ovum) ultimately is developed. - tmeehan - 2010-09-07T02:11:16Z - EHDAA2:0000505 - EMAPA:17965 - FMA:84772 - ISBN:0721662544 - VHOG:0000661 - ovary primordial germ cell - ovigerm - cell - ooblast - - - - - A primordial cell from which an oocyte (ovum) ultimately is developed. - GOC:tfm - - - - - ovary primordial germ cell - VHOG:0000661 - - - - - ovigerm - FMA:84772 - + @@ -27181,19 +10614,7 @@ radial glial cells acting as neural progenitors throughout life. - A fibroblast in the bone marrow. - tmeehan - 2010-09-07T02:25:18Z - FMA:84377 - cell - marrow fibroblast - - - - A fibroblast in the bone marrow. - GOC:tfm - @@ -27201,21 +10622,7 @@ radial glial cells acting as neural progenitors throughout life. - A fibroblasts found in interstitial spaces in the pulmonary tract. Greater numbers of these cells are found in idiopathic pulmonary fibrosis. - tmeehan - 2010-09-07T02:29:38Z - FMA:84467 - pulmonary myofibroblast - pulmonary septal cell - cell - pulmonary interstitial fibroblast - - - - A fibroblasts found in interstitial spaces in the pulmonary tract. Greater numbers of these cells are found in idiopathic pulmonary fibrosis. - GOC:tfm - @@ -27223,19 +10630,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell containing at least one nucleus. - tmeehan - 2010-09-07T03:32:33Z - FMA:67513 - cell - nucleate cell - - - - A cell containing at least one nucleus. - GOC:tfm - @@ -27243,23 +10638,7 @@ radial glial cells acting as neural progenitors throughout life. - A circular smooth muscle cell of the iris, innervated by the ciliary nerves (parasympathetic), and acting to contract the pupil. This muscle cell derives from neuroectoderm. This smooth muscle cell results from transformation of epithelial cells to smooth muscle cells. - tmeehan - 2010-09-08T08:53:42Z - FMA:70611 - smooth muscle fiber of sphincter of pupil - cell - smooth muscle fibre of sphincter of pupil - smooth muscle cell of sphincter of pupil - - - - - A circular smooth muscle cell of the iris, innervated by the ciliary nerves (parasympathetic), and acting to contract the pupil. This muscle cell derives from neuroectoderm. This smooth muscle cell results from transformation of epithelial cells to smooth muscle cells. - GOC:tfm - ISBN:0721662544 - ISBN:0721694128 - + @@ -27268,42 +10647,13 @@ radial glial cells acting as neural progenitors throughout life. - A nonstratified squamous cell located in the ectocervix. - tmeehan - 2010-09-08T09:12:23Z - FMA:86483 - ectocervical squamous cell - cell - squamous cell of ectocervix - - - - A nonstratified squamous cell located in the ectocervix. - GOC:tfm - http://www.bu.edu/histology/p/19404loa.htm - - - OBSOLETE: A lymphocyte that lacks T or B cell surface markers. - tmeehan - 2010-09-07T03:43:42Z - FMA:83601 - cell - obsolete null lymphocyte - true - - - - - OBSOLETE: A lymphocyte that lacks T or B cell surface markers. - GOC:tfm - ISBN:068340007X - + @@ -27312,21 +10662,7 @@ radial glial cells acting as neural progenitors throughout life. - A hematopoeitic stem cell found in the blood. Normally found in very limited numbers in the peripheral circulation (less than 0.1% of all nucleated cells). - tmeehan - 2010-09-07T03:57:09Z - BTO:0002669 - FMA:86711 - PBSC - cell - peripheral blood stem cell - - - - A hematopoeitic stem cell found in the blood. Normally found in very limited numbers in the peripheral circulation (less than 0.1% of all nucleated cells). - GOC:tfm - @@ -27334,19 +10670,7 @@ radial glial cells acting as neural progenitors throughout life. - A tissue macrophage that is in the pleural space. - tmeehan - 2010-09-07T04:16:43Z - FMA:83024 - cell - pleural macrophage - - - - A tissue macrophage that is in the pleural space. - GOC:tfm - @@ -27354,20 +10678,7 @@ radial glial cells acting as neural progenitors throughout life. - A pluripotent stem cell has the ability to form cells from all three germ layers (ectoderm, mesoderm, and endoderm). However, unlike totipotent stem cells, they cell can not generate all the cells of the whole organism such as placenta. - tmeehan - 2010-09-07T04:26:06Z - FMA:70570 - cell - pluripotent stem cell - - - - A pluripotent stem cell has the ability to form cells from all three germ layers (ectoderm, mesoderm, and endoderm). However, unlike totipotent stem cells, they cell can not generate all the cells of the whole organism such as placenta. - GOC:tfm - PMID:19343304 - @@ -27376,20 +10687,7 @@ radial glial cells acting as neural progenitors throughout life. - A stem cell that can differentiate into a cardiac myocyte. - tmeehan - 2010-09-07T04:40:32Z - FMA:75620 - cell - primitive cardiac myocyte - - - - A stem cell that can differentiate into a cardiac myocyte. - GOC:tfm - PMID:16938308 - @@ -27398,21 +10696,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell that is found in a zone occupying the bottom region of the crypt; provide the source of most of the cell types of the intestinal epithelium; proliferate by mitotic division; differentiates into columnar or goblet cells. - tmeehan - 2010-09-08T09:21:22Z - FMA:63379 - stem cell of intestinal crypt of Lieberkuhn - cell - intestinal crypt stem cell - - - - A cell that is found in a zone occupying the bottom region of the crypt; provide the source of most of the cell types of the intestinal epithelium; proliferate by mitotic division; differentiates into columnar or goblet cells. - GOC:tfm - ISBN:0517223651 - @@ -27420,19 +10704,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell of the musculomembranous digestive tube extending from the mouth to the anus. - tmeehan - 2010-09-08T09:26:53Z - cell - epithelial cell of alimentary canal - - - - An epithelial cell of the musculomembranous digestive tube extending from the mouth to the anus. - GOC:tfm - ISBN:0721662544 - @@ -27440,20 +10712,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell of the esophagus. - tmeehan - 2010-09-08T09:28:20Z - CL:1000402 - FMA:63071 - cell - epithelial cell of esophagus - - - - An epithelial cell of the esophagus. - GOC:tfm - @@ -27461,22 +10720,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell of the large intestine. - tmeehan - 2010-09-08T09:28:22Z - CL:1000292 - BTO:0004297 - FMA:256157 - cell - epithelial cell of colon - epithelial cell of large intestine - - - - An epithelial cell of the large intestine. - GOC:tfm - @@ -27484,20 +10728,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell of the small intestine. - tmeehan - 2010-09-08T09:41:46Z - CL:1000293 - FMA:256159 - cell - epithelial cell of small intestine - - - - An epithelial cell of the small intestine. - GOC:tfm - @@ -27506,21 +10737,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell that regulates growth and differentiation of the overlying epithelium. - tmeehan - 2010-09-08T09:50:04Z - CALOHA:TS-1266 - FMA:86490 - cell - stromal cell of endometrium - - - - An epithelial cell that regulates growth and differentiation of the overlying epithelium. - GOC:tfm - PMID:11331626 - @@ -27529,22 +10746,7 @@ radial glial cells acting as neural progenitors throughout life. - A supportive cell that has characteristics of glial cell. Processes of this cell envelope the junctions between glomus cells and nerve endings. - tmeehan - 2010-09-08T10:34:45Z - FMA:84188 - carotid body sustentacular cell - cell - supporting cell of carotid body - - - - A supportive cell that has characteristics of glial cell. Processes of this cell envelope the junctions between glomus cells and nerve endings. - GOC:tfm - PMID:8985136 - http://www.copewithcytokines.de/cope.cgi?key=glomus%20cells - @@ -27553,20 +10755,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell of thyroid gland. - tmeehan - 2010-09-08T01:46:51Z - CL:1000297 - FMA:256167 - cell - epithelial cell of thyroid gland - - - - An epithelial cell of thyroid gland. - GOC:tfm - @@ -27574,25 +10763,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell type that varies from squamous to columnar, depending on their activity with microvillus directed luminally. This cell produces and secretes thyroid hormones. - tmeehan - 2010-09-08T01:50:08Z - BTO:0003736 - CALOHA:TS-1285 - FMA:68782 - follicular cell of thyroid gland - principal cell of thyroid gland - thyroid gland follicular cell - cell - thyroid follicular cell - - - - - A cell type that varies from squamous to columnar, depending on their activity with microvillus directed luminally. This cell produces and secretes thyroid hormones. - GOC:tfm - ISBN:0517223651 - + @@ -27600,21 +10771,7 @@ radial glial cells acting as neural progenitors throughout life. - The stem cell from which glial precursor cell arises from. - tmeehan - 2010-09-08T02:14:14Z - FMA:87171 - totipotent neuroepithelial stem cell - cell - neuroepithelial stem cell - - - - The stem cell from which glial precursor cell arises from. - GOC:tfm - PMID:11687496 - @@ -27623,20 +10780,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell of the parathyroid gland. - tmeehan - 2010-09-08T02:29:38Z - CL:1000429 - FMA:70547 - cell - epithelial cell of parathyroid gland - - - - An epithelial cell of the parathyroid gland. - GOC:tfm - @@ -27644,21 +10788,7 @@ radial glial cells acting as neural progenitors throughout life. - An endothelial cell found in the mucosa associated with the facial skeleton. - tmeehan - 2010-09-14T10:40:12Z - CL:1000446 - FMA:70627 - cell - endothelial cell of viscerocranial mucosa - - - - An endothelial cell found in the mucosa associated with the facial skeleton. - GOC:tfm - ISBN:0618947256 - @@ -27666,21 +10796,7 @@ radial glial cells acting as neural progenitors throughout life. - An endothelial cell that lines any of the venous cavities through which blood passes in various glands and organs such as the spleen and liver. - tmeehan - 2010-09-14T10:57:26Z - CL:1000403 - FMA:63134 - cell - endothelial cell of sinusoid - - - - An endothelial cell that lines any of the venous cavities through which blood passes in various glands and organs such as the spleen and liver. - GOC:tfm - ISBN:0618947256 - @@ -27688,20 +10804,7 @@ radial glial cells acting as neural progenitors throughout life. - One of three types of epithelial cells that populate the parathyroid gland; cytological characteristics intermediate between those of the chief cell and of the oxyphil cell. Because only one hormone is produced, the three cell forms are widely believed to be different phases in the life cycle of a single cell type, with the chief cell being its physiologically active stage. - tmeehan - 2010-09-08T02:33:50Z - FMA:69324 - cell - transitional cell of parathyroid gland - - - - One of three types of epithelial cells that populate the parathyroid gland; cytological characteristics intermediate between those of the chief cell and of the oxyphil cell. Because only one hormone is produced, the three cell forms are widely believed to be different phases in the life cycle of a single cell type, with the chief cell being its physiologically active stage. - GOC:tfm - ISBN:0412046911 - @@ -27710,19 +10813,7 @@ radial glial cells acting as neural progenitors throughout life. - A type of enteroendocrine cell found in the stomach that secretes glucagon. - tmeehan - 2010-09-10T10:54:42Z - FMA:83411 - cell - type A cell of stomach - - - - A type of enteroendocrine cell found in the stomach that secretes glucagon. - GOC:tfm - @@ -27732,22 +10823,7 @@ radial glial cells acting as neural progenitors throughout life. - A D cell located in the colon. - tmeehan - 2010-09-10T11:37:35Z - FMA:268744 - colon D-cell - colonc delta cell - delta cell of colon - cell - type D cell of colon - - - - A D cell located in the colon. - GOC:tfm - @@ -27757,22 +10833,7 @@ radial glial cells acting as neural progenitors throughout life. - A type D cell of the small intestine. - tmeehan - 2010-09-10T01:34:22Z - FMA:268736 - delta cell of small intestine - small intestine D-cell - small intestine delta cell - cell - type D cell of small intestine - - - - A type D cell of the small intestine. - GOC:tfm - @@ -27781,22 +10842,7 @@ radial glial cells acting as neural progenitors throughout life. - A type D cell found in the stomach. - tmeehan - 2010-09-10T01:36:03Z - FMA:83410 - delta cell of stomach - stomach D-cell - stomach delta cell - cell - type D cell of stomach - - - - A type D cell found in the stomach. - GOC:tfm - @@ -27805,22 +10851,7 @@ radial glial cells acting as neural progenitors throughout life. - An enteroendocrine cell that stores and secretes Ghrelin. - tmeehan - 2010-09-10T01:47:45Z - FMA:63207 - FMA:63418 - cell - P/D1 enteroendocrine cell - - - - An enteroendocrine cell that stores and secretes Ghrelin. - GOC:tfm - ISBN:0517223651 - PMID:15153415 - @@ -27828,18 +10859,7 @@ radial glial cells acting as neural progenitors throughout life. - An endocrine cell that secretes vasoactive intestinal peptide. - tmeehan - 2010-09-10T01:52:20Z - cell - vasoactive intestinal peptide secreting cell - - - - An endocrine cell that secretes vasoactive intestinal peptide. - GOC:tfm - @@ -27848,22 +10868,7 @@ radial glial cells acting as neural progenitors throughout life. - A type EC enteroendocrine cell in the duodenum and jejunum that stores and secretes motilin and 5-hydroxytryptamine. - tmeehan - 2010-09-10T02:13:47Z - Mo enteroendocrine cell - FMA:62941 - cell - type EC2 enteroendocrine cell - - - - A type EC enteroendocrine cell in the duodenum and jejunum that stores and secretes motilin and 5-hydroxytryptamine. - GOC:tfm - ISBN:0517223651 - PMID:15153415 - @@ -27872,20 +10877,7 @@ radial glial cells acting as neural progenitors throughout life. - A type EC enteredocrine cell in the intestines that stores and secretes substance P and 5-hydroxytryptamine. - tmeehan - 2010-09-10T02:13:49Z - FMA:62940 - cell - type EC1 enteroendocrine cell - - - - A type EC enteredocrine cell in the intestines that stores and secretes substance P and 5-hydroxytryptamine. - GOC:tfm - ISBN:0517223651 - @@ -27893,19 +10885,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell that secretes motilin, a gastric hormone that at low pH inhibits gastric motor activity, whereas at high pH has a stimulating effect. - tmeehan - 2010-09-10T02:31:13Z - cell - motilin secreting cell - - - - A cell that secretes motilin, a gastric hormone that at low pH inhibits gastric motor activity, whereas at high pH has a stimulating effect. - GOC:tfm - MESH:D06.472.317.525 - @@ -27914,21 +10894,7 @@ radial glial cells acting as neural progenitors throughout life. - A type EC enteroendocrine cell type that is numerous in the fundus of the stomach; stores 5-hydroxytryptamine and histamine. - tmeehan - 2010-09-10T02:35:17Z - FMA:63208 - cell - type ECL enteroendocrine cell - - - - A type EC enteroendocrine cell type that is numerous in the fundus of the stomach; stores 5-hydroxytryptamine and histamine. - GOC:tfm - ISBN:0517223651 - PMID:15153415 - @@ -27936,18 +10902,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell type that secretes histamine. - tmeehan - 2010-09-10T03:04:42Z - cell - histamine secreting cell - - - - A cell type that secretes histamine. - GOC:tfm - @@ -27957,45 +10912,13 @@ radial glial cells acting as neural progenitors throughout life. - A PP cell located in the islets of the pancreas. - tmeehan - 2010-09-10T03:30:31Z - BTO:0000805 - FMA:70588 - PP cell of pancreatic islet - PP-cell of pancreatic islet - pancreatic polypeptide-secreting cell - cell - The term PP cell of pancreatic acinus was obsoleted due to a lack of evidence, making PP cell of pancreatic islets synonymous with pancreatic PP cell. - pancreatic PP cell - - - - - A PP cell located in the islets of the pancreas. - GOC:tfm - + - - OBSOLETE: A PP cell located in the pancreatic acinus. Obsoleted due to a lack of published evidence that this cell type is actually found in the pancreatic acinus. - tmeehan - 2010-09-10T03:30:33Z - FMA:85400 - type F cell of pancreatic acinus - cell - obsolete PP cell of pancreatic acinus - true - - - - - OBSOLETE: A PP cell located in the pancreatic acinus. Obsoleted due to a lack of published evidence that this cell type is actually found in the pancreatic acinus. - GOC:tfm - + @@ -28004,20 +10927,7 @@ radial glial cells acting as neural progenitors throughout life. - An enteroendocrine cell commonest in the duodenum and jejunum, rare in ileum, that secretes cholecystokinin. This cell type is involved in the regulation of digestive enzymes and bile. - tmeehan - 2010-09-10T03:44:36Z - FMA:62937 - CCK cell - cell - type I enteroendocrine cell - - - - An enteroendocrine cell commonest in the duodenum and jejunum, rare in ileum, that secretes cholecystokinin. This cell type is involved in the regulation of digestive enzymes and bile. - GOC:tfm - @@ -28026,20 +10936,7 @@ radial glial cells acting as neural progenitors throughout life. - An enteroendocrine cell of duodenum and jejunum that produces gastric inhibitory peptide. - tmeehan - 2010-09-10T03:51:47Z - FMA:62942 - type K enteroendocrine cell - cell - GIP cell - - - - An enteroendocrine cell of duodenum and jejunum that produces gastric inhibitory peptide. - GOC:tfm - @@ -28048,20 +10945,7 @@ radial glial cells acting as neural progenitors throughout life. - A enteroendocrine cell type that is numerous in ileum, present in jejunum and large intestine, few in duodenum. This cell type produces glucagon-like immunoreactants (glicentin, glucagon-37, glucagon-29, GLP-1 and -2) and PYY. - tmeehan - 2010-09-10T03:59:09Z - FMA:62944 - cell - type L enteroendocrine cell - - - - A enteroendocrine cell type that is numerous in ileum, present in jejunum and large intestine, few in duodenum. This cell type produces glucagon-like immunoreactants (glicentin, glucagon-37, glucagon-29, GLP-1 and -2) and PYY. - ISBN:0517223651 - PMID:15153415 - @@ -28070,20 +10954,7 @@ radial glial cells acting as neural progenitors throughout life. - An enteroendorcine cell found in the ileum and jejunum that produces neurotensin. - tmeehan - 2010-09-10T04:08:29Z - FMA:62943 - N cell - cell - type N enteroendocrine cell - - - - An enteroendorcine cell found in the ileum and jejunum that produces neurotensin. - GOC:tfm - @@ -28093,20 +10964,7 @@ radial glial cells acting as neural progenitors throughout life. - Scattered in duodenojejunal mucosa, this enteroendocrine cell secretes secretin and serotonin. - tmeehan - 2010-09-10T04:44:46Z - FMA:62936 - cell - type S enteroendocrine cell - - - - Scattered in duodenojejunal mucosa, this enteroendocrine cell secretes secretin and serotonin. - GOC:tfm - PMID:15153415 - @@ -28115,21 +10973,7 @@ radial glial cells acting as neural progenitors throughout life. - An enteroendocrine cell which produces a gastrin- and cholecystokinin-like peptide. The apical microvilli-rich plasma membrane is in open contact with the small intestine mucosa. This cell type is devoid of gastrin-17 but contains other fragments of the gastrin polypeptide. - tmeehan - 2010-09-13T09:48:34Z - FMA:63421 - cell - type TG enteroendocrine cell - - - - An enteroendocrine cell which produces a gastrin- and cholecystokinin-like peptide. The apical microvilli-rich plasma membrane is in open contact with the small intestine mucosa. This cell type is devoid of gastrin-17 but contains other fragments of the gastrin polypeptide. - DOI:10.1007/978-3-211-99390-3 - GOC:tfm - PMID:7013499 - @@ -28137,21 +10981,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell of the mucosa associated with facial skeleton. - tmeehan - 2010-09-14T11:04:02Z - CL:1000440 - FMA:70581 - cell - ecto-epithelial cell of viscerocranial mucosa - - - - An epithelial cell of the mucosa associated with facial skeleton. - GOC:tfm - ISBN:0323052908 - @@ -28160,22 +10990,7 @@ radial glial cells acting as neural progenitors throughout life. - An enteroendorcine cell found in the fundus and pylorus, this cell type has dense round secretory granules that contain ghrelin. - tmeehan - 2010-09-13T10:12:12Z - FMA:63209 - A-like - X/A-like - cell - type X enteroendocrine cell - - - - An enteroendorcine cell found in the fundus and pylorus, this cell type has dense round secretory granules that contain ghrelin. - GOC:tfm - PMID:20616512 - @@ -28184,23 +10999,7 @@ radial glial cells acting as neural progenitors throughout life. - A taste receptor cell that is characterized by morphologically identifiable synaptic contacts with the gustatory nerve fibers and expression of the synaptic membrane protein-25 (SNAP-25) and NCAM. - tmeehan - 2010-09-13T10:57:21Z - taste bud basal cell - FMA:67940 - type 3 taste cell - cell - type III taste bud cell - - - - - A taste receptor cell that is characterized by morphologically identifiable synaptic contacts with the gustatory nerve fibers and expression of the synaptic membrane protein-25 (SNAP-25) and NCAM. - GOC:tfm - ISBN:0517223651 - PMID:15738192 - + @@ -28208,21 +11007,7 @@ radial glial cells acting as neural progenitors throughout life. - A taste receptor cell that has a short microvilli, a projecting apical region, a large rounded nucleus, and expresses taste chemoreceptors thus making them the transducing cell for taste qualities. - tmeehan - 2010-09-13T10:57:26Z - FMA:62381 - type 2 taste cell - cell - type II taste cell - - - - A taste receptor cell that has a short microvilli, a projecting apical region, a large rounded nucleus, and expresses taste chemoreceptors thus making them the transducing cell for taste qualities. - GOC:tfm - PMID:15738192 - @@ -28231,24 +11016,7 @@ radial glial cells acting as neural progenitors throughout life. - A rounded, mitotically active stem cell which is the source of new cells of the taste bud; located basally. - tmeehan - 2010-09-13T10:57:29Z - taste bud basal cell - FMA:62380 - type 4 taste cell - cell - There is debate about the exact lineage of these cell types from this progenitor. See PMID:15738192. - type IV taste receptor cell - - - - - A rounded, mitotically active stem cell which is the source of new cells of the taste bud; located basally. - GOC:tfm - ISBN:0517223651 - PMID:15738192 - + @@ -28256,20 +11024,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell type that forms the boundary with the surrounding epithelium. - tmeehan - 2010-09-13T10:57:31Z - FMA:67941 - cell - type V taste receptor cell - - - - A cell type that forms the boundary with the surrounding epithelium. - GOC:tfm - ISBN:0517223651 - @@ -28278,25 +11033,7 @@ radial glial cells acting as neural progenitors throughout life. - A densely staining taste receptor cell that contains many dense vacuoles in their apical regions which project into the apical space and bear microvilli. This cell type serves as a supporting cell by surrounding and isolating the other cell types from each other; secrete a dense amorphous material that surrounds the microvilli in the taste pore. This cell type expresses a glial glutumate transporter, GLAST. - tmeehan - 2010-09-13T10:57:35Z - FMA:62356 - dark tongue cell - type I taste cell - type taste 1 cell - cell - type I taste bud cell - - - - - A densely staining taste receptor cell that contains many dense vacuoles in their apical regions which project into the apical space and bear microvilli. This cell type serves as a supporting cell by surrounding and isolating the other cell types from each other; secrete a dense amorphous material that surrounds the microvilli in the taste pore. This cell type expresses a glial glutumate transporter, GLAST. - GOC:tfm - ISBN:0412046911 - ISBN:0517223651 - PMID:15738192 - + @@ -28304,22 +11041,7 @@ radial glial cells acting as neural progenitors throughout life. - A sperm bearing a Y chromosome. Chromosomal and genetic sex is established at fertilization in mammals and depends upon whether an X-bearing sperm or a Y-bearing sperm fertilizes the X-bearing ovum. - tmeehan - 2010-09-13T11:35:24Z - FMA:84058 - Y bearing sperm - Y-bearing sperm - cell - Y chromosome-bearing sperm cell - - - - A sperm bearing a Y chromosome. Chromosomal and genetic sex is established at fertilization in mammals and depends upon whether an X-bearing sperm or a Y-bearing sperm fertilizes the X-bearing ovum. - GOC:tfm - ISBN:0721669743 - @@ -28327,22 +11049,7 @@ radial glial cells acting as neural progenitors throughout life. - A sperm bearing an X chromosome. Chromosomal and genetic sex is established at fertilization in mammals and depends upon whether an X-bearing sperm or a Y-bearing sperm fertilizes the X-bearing ovum. - tmeehan - 2010-09-13T11:35:26Z - FMA:84057 - X bearing sperm - X-bearing sperm - cell - X chromosome-bearing sperm cell - - - - A sperm bearing an X chromosome. Chromosomal and genetic sex is established at fertilization in mammals and depends upon whether an X-bearing sperm or a Y-bearing sperm fertilizes the X-bearing ovum. - GOC:tfm - ISBN:0721669743 - @@ -28350,21 +11057,7 @@ radial glial cells acting as neural progenitors throughout life. - A round or oval neuroepithelial cell that contacts other type I cells or capillaries. They occur in clusters that are surrounded by sheath cells (type-II cells) in the carotid body. This cell type is capable of secreting a number of neurotransmitters. - tmeehan - 2010-09-13T01:40:21Z - FMA:84186 - glomus cell - cell - type I cell of carotid body - - - - A round or oval neuroepithelial cell that contacts other type I cells or capillaries. They occur in clusters that are surrounded by sheath cells (type-II cells) in the carotid body. This cell type is capable of secreting a number of neurotransmitters. - GOC:tfm - ISBN:0517223651 - @@ -28372,26 +11065,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell of the thymus. Epithelial reticular cells are pleomorphic, stellate, non-phagocytic cells which seem to be supportive in function and are held together by desmosomes. They replace the fibroblastoid reticular cells found in other lymphoid organs. Other epithelial cells in the medulla have the ultrastructure of secretory cells. Although different epithelial cells throughout the thymus appear alike by light microscopy their ultrastructure and function varies. - tmeehan - 2010-09-13T02:34:22Z - CL:1000459 - CALOHA:TS-1040 - FMA:72208 - epithelial cell of thymus gland - epithelial reticular cell - epithelial reticular cell of thymus - thymic epithelial cell - cell - epithelial cell of thymus - - - - - An epithelial cell of the thymus. Epithelial reticular cells are pleomorphic, stellate, non-phagocytic cells which seem to be supportive in function and are held together by desmosomes. They replace the fibroblastoid reticular cells found in other lymphoid organs. Other epithelial cells in the medulla have the ultrastructure of secretory cells. Although different epithelial cells throughout the thymus appear alike by light microscopy their ultrastructure and function varies. - FMA:72208 - GOC:tfm - + @@ -28399,21 +11073,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell with a well defined Golgi apparatus that makes up the continuous layer of cells bordering the thymic tissue beneath the capsule. - tmeehan - 2010-09-13T02:37:23Z - FMA:72209 - subcapsular thymic epithelial cell - cell - type-1 epithelial cell of thymus - - - - An epithelial cell with a well defined Golgi apparatus that makes up the continuous layer of cells bordering the thymic tissue beneath the capsule. - GOC:tfm - PMID:9264335 - @@ -28421,24 +11081,7 @@ radial glial cells acting as neural progenitors throughout life. - A thymic epithelial cell that has an eccentric, round, or irregularly shaped hetero or euchromatic nucleus. The hallmark of this cell type is the presence of vacuoles, which are clustered in one area of the cytoplasm in the vicinity of the nucleus. The vacuoles are small and acquire a grape-like form, occasionally showing delicate internal microvillous projections. - tmeehan - 2010-09-13T02:37:26Z - FMA:72214 - cystic thymic epithelial cells - large mTEC - large medullary thymic epithelial cells - cell - type-6 epithelial cell of thymus - - - - - A thymic epithelial cell that has an eccentric, round, or irregularly shaped hetero or euchromatic nucleus. The hallmark of this cell type is the presence of vacuoles, which are clustered in one area of the cytoplasm in the vicinity of the nucleus. The vacuoles are small and acquire a grape-like form, occasionally showing delicate internal microvillous projections. - GOC:tfm - PMID:19721455 - PMID:9264335 - + @@ -28447,22 +11090,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell with high nuclear and cytoplasmic electron-density. This cell type is found in the deeper portions of the cortex but is more abundant in the medulla of the thymus. - tmeehan - 2010-09-13T02:37:45Z - FMA:72212 - dark thymic epithelial cell - cell - type-4 epithelial cell of thymus - - - - An epithelial cell with high nuclear and cytoplasmic electron-density. This cell type is found in the deeper portions of the cortex but is more abundant in the medulla of the thymus. - FMA:0412046911 - GOC:tfm - PMID:9264335 - @@ -28470,20 +11098,7 @@ radial glial cells acting as neural progenitors throughout life. - A thymic epithelial cell with moderate nuclear and cytoplasmic electron-density. Scattered in the cortex, this cell type is predominant in the mid and deep cortex. - tmeehan - 2010-09-13T02:37:51Z - FMA:72211 - intermediate thymic epithelial cell - cell - type-3 epithelial cell of thymus - - - - A thymic epithelial cell with moderate nuclear and cytoplasmic electron-density. Scattered in the cortex, this cell type is predominant in the mid and deep cortex. - PMID:9264335 - @@ -28491,25 +11106,7 @@ radial glial cells acting as neural progenitors throughout life. - A thymic epithelial cell type with low nuclear and cytoplasmic electrondensity; has a round, euchromatic nucleus and occurs in small groups at the corticomedullary junction or scattered singly in the medulla. - tmeehan - 2010-09-13T02:37:54Z - FMA:72213 - undifferentiated mTEC - undifferentiated medullary thymic epithelial cell - undifferentiated thymic epithelial cell - cell - type-5 epithelial cell of thymus - - - - - A thymic epithelial cell type with low nuclear and cytoplasmic electrondensity; has a round, euchromatic nucleus and occurs in small groups at the corticomedullary junction or scattered singly in the medulla. - GOC:tfm - ISBN:0412046911 - PMID:19721455 - PMID:9264335 - + @@ -28517,22 +11114,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell scattered in the cortex, predominant in the outer cortex with a large pale nucleus and a prominent nucleolus. - tmeehan - 2010-09-13T02:37:58Z - FMA:72210 - pale thymic epithelial cell - cell - type-2 epithelial cell of thymus - - - - An epithelial cell scattered in the cortex, predominant in the outer cortex with a large pale nucleus and a prominent nucleolus. - GOC:tfm - ISBN:0412046911 - PMID:9264335 - @@ -28540,21 +11122,7 @@ radial glial cells acting as neural progenitors throughout life. - A small medullary thymic epithelial cell with a spindle shape, often arranged in groups and connected to each other by large desmosomes and interdigitations. The cytoplasm is sparse, with scanty organelles and thick bundles of cytokeratin. - tmeehan - 2010-09-13T03:23:25Z - spindle shaped mTEC - spindle shaped medullary thymic epithelial cell - cell - type-7 epithelial cell of thymus - - - - A small medullary thymic epithelial cell with a spindle shape, often arranged in groups and connected to each other by large desmosomes and interdigitations. The cytoplasm is sparse, with scanty organelles and thick bundles of cytokeratin. - GOC:tfm - PMID:19721455 - @@ -28562,20 +11130,7 @@ radial glial cells acting as neural progenitors throughout life. - A synovial cell type that resembles fibroblasts, has abundant granular endoplasmic reticulum but contains fewer vacuoles and vesicles. This cell type secretes glycoproteins and hyaluronic acid. - tmeehan - 2010-09-13T03:39:14Z - FMA:66788 - cell - type B synovial cell - - - - A synovial cell type that resembles fibroblasts, has abundant granular endoplasmic reticulum but contains fewer vacuoles and vesicles. This cell type secretes glycoproteins and hyaluronic acid. - GOC:tfm - ISBN:0517223651 - @@ -28583,21 +11138,7 @@ radial glial cells acting as neural progenitors throughout life. - A synovial cell that is macrophage-like, characterized by surface ruffles or lamellipodia, plasma membrane invaginations and associated micropinocytotic vesicles, Golgi apparatus and little granular endoplasmic reticulum. - tmeehan - 2010-09-13T03:39:17Z - FMA:66787 - type A synoviocyte - cell - type A synovial cell - - - - A synovial cell that is macrophage-like, characterized by surface ruffles or lamellipodia, plasma membrane invaginations and associated micropinocytotic vesicles, Golgi apparatus and little granular endoplasmic reticulum. - GOC:tfm - ISBN:0517223651 - @@ -28607,20 +11148,7 @@ radial glial cells acting as neural progenitors throughout life. - A ciliated epithelial cell of the retina, this cell type uptakes sodium chloride and passes it to non-pigmented ciliary epithelial cells. - tmeehan - 2010-09-13T04:09:27Z - FMA:70606 - PE - cell - pigmented ciliary epithelial cell - - - - A ciliated epithelial cell of the retina, this cell type uptakes sodium chloride and passes it to non-pigmented ciliary epithelial cells. - PMID:15106942 - @@ -28630,21 +11158,7 @@ radial glial cells acting as neural progenitors throughout life. - A multi-ciliated cell of the retina that lacks visual pigment and contributes to aqueous humor by secreting chloride ions. This cell type maintains gap junctions with pigmented epithelial cells. - tmeehan - 2010-09-13T04:09:31Z - FMA:70607 - NPE - cell - non-pigmented ciliary epithelial cell - - - - A multi-ciliated cell of the retina that lacks visual pigment and contributes to aqueous humor by secreting chloride ions. This cell type maintains gap junctions with pigmented epithelial cells. - GOC:tfm - PMID:15106942 - @@ -28654,21 +11168,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell of the distal convoluted tubule of the kidney that helps regulate systemic levels of potassium, sodium, calcium, and pH. - FMA:62125 - FMA:70981 - KUPO:0001055 - kidney distal tubule epithelial cell - cell - epithelial cell of distal tubule - - - - An epithelial cell of the distal convoluted tubule of the kidney that helps regulate systemic levels of potassium, sodium, calcium, and pH. - GOC:tfm - ISBN:0517223651 - @@ -28679,21 +11179,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell of the proximal tubule of the kidney. - FMA:62125 - FMA:70973 - KUPO:0001044 - kidney proximal tubule epithelial cell - cell - epithelial cell of proximal tubule - - - - An epithelial cell of the proximal tubule of the kidney. - GOC:tfm - ISBN:1-4160-2328-3 - @@ -28701,19 +11187,7 @@ radial glial cells acting as neural progenitors throughout life. - A brush border epithelial cell located in the proximal tubule of the kidney that detects fluid flow. - tmeehan - 2010-09-14T11:29:20Z - cell - brush border cell of the proximal tubule - - - - A brush border epithelial cell located in the proximal tubule of the kidney that detects fluid flow. - GOC:tfm - ISBN:1-4160-2328-3 - @@ -28721,20 +11195,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell of a skin gland. - tmeehan - 2010-09-14T12:00:07Z - FMA:70657 - epithelial cell of gland of skin - cell - epithelial cell of skin gland - - - - An epithelial cell of a skin gland. - GOC:tfm - @@ -28743,21 +11204,7 @@ radial glial cells acting as neural progenitors throughout life. - A basophil chromphil cell of the anterior pitiutary gland that produce adrenocorticotropic hormone, melanocyte-stimulating hormone and lipotropin. This cell type is irregular in shape and has short dendritic processes which are inserted among other neighboring cells; - tmeehan - 2010-09-14T02:08:23Z - BTO:0002509 - FMA:83098 - cell - corticotroph - - - - A basophil chromphil cell of the anterior pitiutary gland that produce adrenocorticotropic hormone, melanocyte-stimulating hormone and lipotropin. This cell type is irregular in shape and has short dendritic processes which are inserted among other neighboring cells; - GOC:tfm - ISBN:0517223651 - @@ -28767,19 +11214,7 @@ radial glial cells acting as neural progenitors throughout life. - An acidophil cell of the anterior pitiuatry gland that produces both prolactin and growth hormone. - tmeehan - 2010-09-14T02:25:34Z - FMA:83097 - cell - mammosomatotroph - - - - An acidophil cell of the anterior pitiuatry gland that produces both prolactin and growth hormone. - GOC:tfm - @@ -28788,26 +11223,7 @@ radial glial cells acting as neural progenitors throughout life. - An acidophilic cell of the anterior pituitary that produces prolactin. - tmeehan - 2010-09-14T02:30:57Z - FMA:83096 - epsilon-acidophil - lactotrope - lactotroph - lactotropic cell - mammotrope - mammotrophic cell - mammotropic cell - cell - mammotroph - - - - - An acidophilic cell of the anterior pituitary that produces prolactin. - SANBI:mhl - + @@ -28816,22 +11232,7 @@ radial glial cells acting as neural progenitors throughout life. - An acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin. - tmeehan - 2010-09-14T02:33:09Z - FMA:83095 - somatotrope - somatotropic cell - somatrophic cell - cell - somatotroph - - - - An acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin. - SANBI:mhl - @@ -28840,23 +11241,7 @@ radial glial cells acting as neural progenitors throughout life. - An ecto-epithelial cell of the prostate gland that secretes hormones. - tmeehan - 2010-09-14T03:01:58Z - CALOHA:TS-1280 - FMA:74390 - FMA:86774 - glandular cell of prostate - neuro-epithelial cell of prostate gland - cell - endocrine-paracrine cell of prostate gland - - - - - An ecto-epithelial cell of the prostate gland that secretes hormones. - GOC:tfm - + @@ -28864,20 +11249,7 @@ radial glial cells acting as neural progenitors throughout life. - An auditory epithelial support cell located in the vestibular epithelium that has many hallmarks of glial cells. This cell type express glial markers such as vimentin, S100, glutamate-aspartate transporter, low affinity neurotrophin receptor p75, glial fibrillary acidic protein, and proteolipid protein. - tmeehan - 2010-09-14T03:20:01Z - FMA:75809 - cell - external supporting cell of vestibular epithelium - - - - An auditory epithelial support cell located in the vestibular epithelium that has many hallmarks of glial cells. This cell type express glial markers such as vimentin, S100, glutamate-aspartate transporter, low affinity neurotrophin receptor p75, glial fibrillary acidic protein, and proteolipid protein. - GOC:tfm - PMID:20837532 - @@ -28886,19 +11258,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial supporting cell located in the cochlea. - tmeehan - 2010-09-14T03:31:38Z - FMA:79796 - cell - supporting cell of cochlea - - - - An epithelial supporting cell located in the cochlea. - GOC:tfm - @@ -28906,20 +11266,7 @@ radial glial cells acting as neural progenitors throughout life. - A supporting cell of the vestibular epithelium. - tmeehan - 2010-09-14T03:31:44Z - FMA:75607 - cell - supporting cell of vestibular epithelium - - - - A supporting cell of the vestibular epithelium. - GOC:tfm - PMID:20837532 - @@ -28927,19 +11274,7 @@ radial glial cells acting as neural progenitors throughout life. - An external limiting cell found in the vestibular epithelium. - tmeehan - 2010-09-14T03:33:50Z - FMA:75808 - cell - external limiting cell of vestibular epithelium - - - - An external limiting cell found in the vestibular epithelium. - GOC:tfm - @@ -28947,20 +11282,7 @@ radial glial cells acting as neural progenitors throughout life. - A mesothelial cell capable of circulating in the blood by first losing its squamous character. This cell can incorporate into the regenerating mesothelium. - tmeehan - 2010-09-15T10:47:11Z - FMA:86712 - cell - periperhal blood mesothelial cell - - - - A mesothelial cell capable of circulating in the blood by first losing its squamous character. This cell can incorporate into the regenerating mesothelium. - GOC:tfm - PMID:14592528 - @@ -28969,21 +11291,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell that is part of the nervous system. - tmeehan - 2010-09-15T01:34:57Z - CALOHA:TS-2040 - FMA:70333 - cell - neural cell - - - - A cell that is part of the nervous system. - GOC:tfm - ISBN:0618947256 - @@ -28992,22 +11300,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone. - tmeehan - 2010-09-15T03:01:54Z - CL:1000406 - CALOHA:TS-2096 - FMA:63875 - cell - connective tissue cell - - - - A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone. - GOC:tfm - ISBN:0618947256 - @@ -29015,22 +11308,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell of the embryo. - tmeehan - 2010-09-15T03:39:21Z - CALOHA:TS-0263 - FMA:82840 - FMA:82841 - WBbt:0007028 - cell - embryonic cell - - - - A cell of the embryo. - FMA:0618947256 - @@ -29039,26 +11317,7 @@ radial glial cells acting as neural progenitors throughout life. - A stem cell of embryonic origin. - tmeehan - 2010-09-15T03:44:35Z - BTO:0001086 - CALOHA:TS-0263 - FMA:82841 - ESC - cell - This is an in vitro cell type and may be removed in future releases. These cells are reportedly SSEA-4-positive, CD73-negative, and CD324-positive. - embryonic stem cell - - - - - A stem cell of embryonic origin. - GOC:dsd - GOC:tfm - ISBN:068340007X - PMID:18179856 - + @@ -29066,21 +11325,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell of a fetus which is suspended in the amniotic fluid. Amniocytes are considered to arise from several tissues including fetal skin, the fetal urinary tract, umbilical cord, and the inner amniotic surface. - tmeehan - 2010-09-20T10:13:37Z - BTO:0000066 - cell - amniocyte - - - - A cell of a fetus which is suspended in the amniotic fluid. Amniocytes are considered to arise from several tissues including fetal skin, the fetal urinary tract, umbilical cord, and the inner amniotic surface. - BFO:0000066 - GOC:tfm - PMID:3211847 - @@ -29088,20 +11333,7 @@ radial glial cells acting as neural progenitors throughout life. - A myoepithelial cell that surrounds milk-secreting luminal epithelial cells. This cell type contracts under the stimulation of oxytocin and is attached to the basement membrane by hemidesmosomes and to the adjacent luminal cells by desmosomes. This cell type expresses high level of keratin-14 and is estrogen receptor alpha negative. - tmeehan - 2010-09-20T11:42:14Z - cell - myoepithelial cell of mammary gland - - - - A myoepithelial cell that surrounds milk-secreting luminal epithelial cells. This cell type contracts under the stimulation of oxytocin and is attached to the basement membrane by hemidesmosomes and to the adjacent luminal cells by desmosomes. This cell type expresses high level of keratin-14 and is estrogen receptor alpha negative. - GOC:tfm - PMID:11250738 - PMID:19022771 - @@ -29111,25 +11343,7 @@ radial glial cells acting as neural progenitors throughout life. - The milk-producing cell of the alveolar unit that emerges during pregnancy. - tmeehan - 2010-09-20T01:30:57Z - CL:0002230 - CL:1000476 - FMA:74506 - FMA:79866 - epithelial cell of lactiferous gland - luminal cell of alveolus of lactiferous gland - cell - mammary alveolar cell - - - - - The milk-producing cell of the alveolar unit that emerges during pregnancy. - GOC:tfm - PMID:19022771 - + @@ -29138,20 +11352,7 @@ radial glial cells acting as neural progenitors throughout life. - A mammary epithelial cell that occurs in the lumen of the ductal and alveoli structure in the breast. - tmeehan - 2010-09-20T01:37:53Z - FMA:73280 - cell - luminal epithelial cell of mammary gland - - - - A mammary epithelial cell that occurs in the lumen of the ductal and alveoli structure in the breast. - GOC:tfm - PMID:19022771 - @@ -29160,22 +11361,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell of the mammary gland. - tmeehan - 2010-09-20T01:49:37Z - BTO:0004300 - breast epithelial cell - mammary epithelial cell - cell - mammary gland epithelial cell - - - - An epithelial cell of the mammary gland. - GOC:tfm - PMID:19022771 - @@ -29183,19 +11369,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell of the bronchus. - tmeehan - 2010-09-20T02:00:00Z - BTO:0002922 - cell - bronchial epithelial cell - - - - An epithelial cell of the bronchus. - GOC:tfm - @@ -29203,18 +11377,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell type that lacks the columnar shape typical for other respiratory epithelial cells. This cell type is able to differentiate into other respiratory epithelial cells in response to injury. - tmeehan - 2010-09-20T02:10:36Z - cell - basal epithelial cell of tracheobronchial tree - - - - An epithelial cell type that lacks the columnar shape typical for other respiratory epithelial cells. This cell type is able to differentiate into other respiratory epithelial cells in response to injury. - GOC:tfm - @@ -29222,19 +11385,7 @@ radial glial cells acting as neural progenitors throughout life. - An undifferentiated columnar cell of the bronchus epithelium - tmeehan - 2010-09-20T02:17:58Z - cell - undifferentiated cell of bronchus epithelium - - - - An undifferentiated columnar cell of the bronchus epithelium - GOC:tfm - PMID:18757316 - @@ -29243,19 +11394,7 @@ radial glial cells acting as neural progenitors throughout life. - A ciliated cell of the bronchus. - tmeehan - 2010-09-20T02:21:12Z - cell - ciliated cell of the bronchus - - - - A ciliated cell of the bronchus. - GOC:tfm - PMID:18757316 - @@ -29263,19 +11402,7 @@ radial glial cells acting as neural progenitors throughout life. - A fat cell derived from a neural crest cell. - tmeehan - 2010-09-20T02:25:25Z - cell - neural crest derived fat cell - - - - A fat cell derived from a neural crest cell. - GOC:tfm - PMID:17507398 - @@ -29283,20 +11410,7 @@ radial glial cells acting as neural progenitors throughout life. - An undifferentiated fibroblast that can be stimulated to form a fat cell. - tmeehan - 2010-09-20T02:31:53Z - BTO:0001107 - cell - preadipocyte - - - - An undifferentiated fibroblast that can be stimulated to form a fat cell. - GOC:tfm - PMID:18793119 - @@ -29304,19 +11418,7 @@ radial glial cells acting as neural progenitors throughout life. - A preadipocyte that is capable of differentiating into a brown adipocyte. This cell type expresses uncoupling protein-1, PPAR-gamma, PR-domain-containing 16; and PGC-1alpha (peroxisome proliferator-activated receptor-gamma (PPARgamma) coactivator-1alpha). - tmeehan - 2010-09-20T02:38:38Z - cell - brown preadipocyte - - - - A preadipocyte that is capable of differentiating into a brown adipocyte. This cell type expresses uncoupling protein-1, PPAR-gamma, PR-domain-containing 16; and PGC-1alpha (peroxisome proliferator-activated receptor-gamma (PPARgamma) coactivator-1alpha). - GOC:tfm - PMID:18719589 - @@ -29324,19 +11426,7 @@ radial glial cells acting as neural progenitors throughout life. - An endothelial cell that lines the oral cavitiy including the mucosa of the gums, the palate, the lip, and the cheek. - tmeehan - 2010-09-20T02:52:54Z - cell - buccal mucosa cell - - - - An endothelial cell that lines the oral cavitiy including the mucosa of the gums, the palate, the lip, and the cheek. - GOC:tfm - MESH:A10.615.550.599 - @@ -29345,19 +11435,7 @@ radial glial cells acting as neural progenitors throughout life. - A stem cell located in the bulge of the hair follicle that can give rise to regenerate the new follicle with each hair cycle and to reepithelialize the epidermis during wound repair. - tmeehan - 2010-09-20T03:07:03Z - bulge keratinocyte - cell - keratinocyte stem cell - - - - A stem cell located in the bulge of the hair follicle that can give rise to regenerate the new follicle with each hair cycle and to reepithelialize the epidermis during wound repair. - PMID:15339667 - @@ -29365,29 +11443,7 @@ radial glial cells acting as neural progenitors throughout life. - A natural killer cell that is developmentally immature, has the phenotype CD34-negative, CD56-negative, CD117-positive, CD122-positive,and CD161-positive. - tmeehan - 2010-09-21T10:06:53Z - cell - p-NK - Human markers; killer cell immunoglobulin-like receptor 2DL1 is used as a representative example (PRO at this time lacks a KIR superfamily). - CD56-positive, CD161-positive immature natural killer cell - - - - - A natural killer cell that is developmentally immature, has the phenotype CD34-negative, CD56-negative, CD117-positive, CD122-positive,and CD161-positive. - GOC:add - GO_REF:0000031 - ISBN:0781735149 - PMID:12457618 - - - - - p-NK - PMID:12457618 - + @@ -29396,20 +11452,7 @@ radial glial cells acting as neural progenitors throughout life. - A prostate epithelial cell that is CD133-positive, CD44-positive, integrin A2beta3-high. This cell is a stem cell for the prostate epithelium. - tmeehan - 2010-09-20T03:21:06Z - CD133-positive prostate epithelial cell - cell - prostate stem cell - - - - A prostate epithelial cell that is CD133-positive, CD44-positive, integrin A2beta3-high. This cell is a stem cell for the prostate epithelium. - GOC:tfm - PMID:15226377 - @@ -29417,18 +11460,7 @@ radial glial cells acting as neural progenitors throughout life. - The exocrine cell of the prostate, this epithelial cell secretes prostatic acid phosphotase and PSA, and is dependent on androgen hormones for survival. - tmeehan - 2010-09-20T03:34:05Z - cell - luminal cell of prostate epithelium - - - - The exocrine cell of the prostate, this epithelial cell secretes prostatic acid phosphotase and PSA, and is dependent on androgen hormones for survival. - GOC:tfm - @@ -29436,19 +11468,7 @@ radial glial cells acting as neural progenitors throughout life. - An undifferentiated cell of the prostate epithelium that lacks secretory activity. - tmeehan - 2010-09-20T03:34:10Z - cell - basal cell of prostate epithelium - - - - An undifferentiated cell of the prostate epithelium that lacks secretory activity. - GOC:tfm - PMCID:PMC2673349 - @@ -29456,19 +11476,7 @@ radial glial cells acting as neural progenitors throughout life. - A circulating endothelial cell of the phenotype CD146-positive, CD105-positive, CD45-negative. This cell type is indicative of recent vascular damage. - tmeehan - 2010-09-20T03:49:58Z - cell - circulating endothelial cell - - - - A circulating endothelial cell of the phenotype CD146-positive, CD105-positive, CD45-negative. This cell type is indicative of recent vascular damage. - GOC:tfm - PMID:19652886 - @@ -29476,21 +11484,7 @@ radial glial cells acting as neural progenitors throughout life. - A natural killer cell subset that is found in the decidual of the uterus and is CD56-high, Galectin-1-positive and CD16-negative. This cell type represents the most abundant immune cell type in the decidual during the first trimester of pregnancy. - tmeehan - 2010-09-20T04:00:02Z - dNK cell - decidual NK cell - cell - decidual natural killer cell - - - - A natural killer cell subset that is found in the decidual of the uterus and is CD56-high, Galectin-1-positive and CD16-negative. This cell type represents the most abundant immune cell type in the decidual during the first trimester of pregnancy. - PMID:14568979 - PMID:19800965 - @@ -29498,29 +11492,7 @@ radial glial cells acting as neural progenitors throughout life. - A natural killer cell that is developmentally immature, has the phenotype CD34-negative, CD56-negative, CD117-positive, CD122-positive,and CD161-positive. - tmeehan - 2010-09-20T04:33:11Z - cell - p-NK - Human markers; killer cell immunoglobulin-like receptor 2DL1 is used as a representative example (PRO at this time lacks a KIR superfamily). - CD56-negative, CD161-positive immature natural killer cell - - - - - A natural killer cell that is developmentally immature, has the phenotype CD34-negative, CD56-negative, CD117-positive, CD122-positive,and CD161-positive. - GOC:add - GO_REF:0000031 - ISBN:0781735149 - PMID:12457618 - - - - - p-NK - PMID:12457618 - + @@ -29528,22 +11500,7 @@ radial glial cells acting as neural progenitors throughout life. - An immature natural killer cell that is NK1.1-positive, DX5-positive, Ly49-positive, CD27-low and CD11b-low. This cell type is found in high numbers in the liver. - tmeehan - 2010-09-20T04:41:01Z - preNK.BM - cell - Markers are associated with mouse cells. - CD27-low, CD11b-low immature natural killer cell - - - - An immature natural killer cell that is NK1.1-positive, DX5-positive, Ly49-positive, CD27-low and CD11b-low. This cell type is found in high numbers in the liver. - GOC:tfm - PMID:19949422 - http:www.immgen.org/index_content.html - @@ -29551,19 +11508,7 @@ radial glial cells acting as neural progenitors throughout life. - An immature natural killer cell that is NK1.1-positive and DX-5 negative. - tmeehan - 2010-09-21T10:11:44Z - cell - Dx5-negative, NK1.1-positive immature natural killer cell - - - - An immature natural killer cell that is NK1.1-positive and DX-5 negative. - GOC:tfm - PMID:12766763 - @@ -29571,19 +11516,7 @@ radial glial cells acting as neural progenitors throughout life. - A mature natural killer cell that is CD27-high and CD11b-high. This cell type is capable of interferon-gamma secretion. - tmeehan - 2010-09-21T10:19:49Z - cell - CD27-high, CD11b-high natural killer cell - - - - A mature natural killer cell that is CD27-high and CD11b-high. This cell type is capable of interferon-gamma secretion. - GOC:tfm - PMID:19949422 - @@ -29591,19 +11524,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD27-low, CD11b-high natural killer cell that has a higher threshold of activation due to higher expression of inhibitory receptors. - tmeehan - 2010-09-21T10:19:54Z - cell - CD27-low, CD11b-high natural killer cell - - - - A CD27-low, CD11b-high natural killer cell that has a higher threshold of activation due to higher expression of inhibitory receptors. - GOC:tfm - PMID:1994922 - @@ -29611,19 +11532,7 @@ radial glial cells acting as neural progenitors throughout life. - A natural killer cell that is CD27-high and CD11b-low. - tmeehan - 2010-09-21T10:20:00Z - cell - CD27-high, CD11b-low natural killer cell - - - - A natural killer cell that is CD27-high and CD11b-low. - GOC:tfm - PMID:1994922 - @@ -29631,29 +11540,7 @@ radial glial cells acting as neural progenitors throughout life. - An endothelial cell that lines the intracavitary lumen of the heart, separating the circulating blood from the underlying myocardium. This cell type releases a number of vasoactive substances including prostacyclin, nitrous oxide and endothelin. - tmeehan - 2010-09-21T04:33:05Z - CL:1000475 - FMA:75621 - endocardial endothelial cell - endothelial cell of endocardium - cell - endocardial cell - - - - - An endothelial cell that lines the intracavitary lumen of the heart, separating the circulating blood from the underlying myocardium. This cell type releases a number of vasoactive substances including prostacyclin, nitrous oxide and endothelin. - GOC:tfm - ISSN:0452-3458 - - - - - endothelial cell of endocardium - FMA:75621 - + @@ -29661,22 +11548,7 @@ radial glial cells acting as neural progenitors throughout life. - A multi-fate stem cell that is able to differentiate into the pancreas alpha, beta and delta endocrine cells. This cell type expresses neurogenin-3 and Isl-1. - tmeehan - 2010-09-21T04:41:06Z - pancreatic endocrine progenitor - pancreatic islet progenitor cell - cell - progenitor cell of endocrine pancreas - - - - A multi-fate stem cell that is able to differentiate into the pancreas alpha, beta and delta endocrine cells. This cell type expresses neurogenin-3 and Isl-1. - GOC:tfm - PMID:20025937 - PMID:20217494 - @@ -29684,19 +11556,7 @@ radial glial cells acting as neural progenitors throughout life. - A hematopoietic stem cell that exists during embryogenesis. - tmeehan - 2010-09-22T09:05:13Z - cell - gestational hematopoietic stem cell - - - - A hematopoietic stem cell that exists during embryogenesis. - GOC:tfm - ISBN:978-60327-246-6 - @@ -29704,20 +11564,7 @@ radial glial cells acting as neural progenitors throughout life. - A hematopoietic stem cell that resides in the fetal liver. In mice, this cell type is first observed at E10.5. This cell type is MHC-positive, HSA-positive, AA4.1-positive, CD45-positive, Sca-1 positive, CD150-positive, CD48-negative and CD244-negative. - tmeehan - 2010-09-22T09:08:32Z - cell - fetal liver hematopoietic progenitor cell - - - - A hematopoietic stem cell that resides in the fetal liver. In mice, this cell type is first observed at E10.5. This cell type is MHC-positive, HSA-positive, AA4.1-positive, CD45-positive, Sca-1 positive, CD150-positive, CD48-negative and CD244-negative. - GOC:tfm - ISBN:978-1-60327-346-6 - PMID:16569764 - @@ -29726,20 +11573,7 @@ radial glial cells acting as neural progenitors throughout life. - A hematopoietic stem found in the yolk sac. In mice, this cell type is Sca-1-negative, CD45-negative, MHC-negative, HSA-positive, AA4.1-positive, CD44-positive. - tmeehan - 2010-09-22T09:08:34Z - hemangioblast precursor - cell - yolk sac hematopoietic stem cell - - - - A hematopoietic stem found in the yolk sac. In mice, this cell type is Sca-1-negative, CD45-negative, MHC-negative, HSA-positive, AA4.1-positive, CD44-positive. - GOC:tfm - doi:10.1097/MOH.0b013e3282f97ae1 - @@ -29747,23 +11581,7 @@ radial glial cells acting as neural progenitors throughout life. - A large nucleated basophilic erythrocyte found in mammalian embryos. This cell type arises from the blood islands of yolk sacs and expresses different types of hemoglobins (beta-H1, gamma-1 and zeta) than adult erythrocytes. Considered a type of erythroblast as this cell type can enucleate in circulation. - tmeehan - 2010-09-22T09:27:05Z - primitive erythroblast - primitive erythrocyte - primitive erythroid cell - cell - primitive red blood cell - - - - - A large nucleated basophilic erythrocyte found in mammalian embryos. This cell type arises from the blood islands of yolk sacs and expresses different types of hemoglobins (beta-H1, gamma-1 and zeta) than adult erythrocytes. Considered a type of erythroblast as this cell type can enucleate in circulation. - DOI:10.1097/MOH.0b013e3282f97ae1 - GOC:tfm - PMID:11495698 - + @@ -29771,21 +11589,7 @@ radial glial cells acting as neural progenitors throughout life. - A primitive erythrocyte that has undergone enucleation. This cell type is 3-6 fold bigger than the fetal derived erythrocytes that they co-circulate with during fetal development. Expresses epsilon-gamma hemoglobin chains. - tmeehan - 2010-09-22T09:35:16Z - megalocyte - cell - primitive reticulocyte - - - - A primitive erythrocyte that has undergone enucleation. This cell type is 3-6 fold bigger than the fetal derived erythrocytes that they co-circulate with during fetal development. Expresses epsilon-gamma hemoglobin chains. - GOC:tfm - PMID:11495698 - doi:10.1097/MOH.0b013e3282f97ae1 - @@ -29793,20 +11597,7 @@ radial glial cells acting as neural progenitors throughout life. - A fetal liver derived enucleated erythrocyte. This erythrocyte resembles adult erythrocytes in that they are small (3- to 6- times smaller than primitive erythrocytes) and produce adult hemaglobins. - tmeehan - 2010-09-22T09:38:32Z - macrocyte - cell - fetal derived definitive erythrocyte - - - - A fetal liver derived enucleated erythrocyte. This erythrocyte resembles adult erythrocytes in that they are small (3- to 6- times smaller than primitive erythrocytes) and produce adult hemaglobins. - GOC:tfm - PMID:11495698 - @@ -29814,18 +11605,7 @@ radial glial cells acting as neural progenitors throughout life. - Derived from the Greek word pyren (the pit of a stone fruit), this is a transient nucleated cell type that results from exclusion of the nucleus from the primitive erythrocyte. - tmeehan - 2010-09-22T10:02:37Z - cell - pyrenocyte - - - - Derived from the Greek word pyren (the pit of a stone fruit), this is a transient nucleated cell type that results from exclusion of the nucleus from the primitive erythrocyte. - GOC:tfm - @@ -29833,19 +11613,7 @@ radial glial cells acting as neural progenitors throughout life. - A hematopoietic stem cell of the placenta. This cell type is first observed E10.5 This cell type may give rise to fetal liver hematopoietic stem cells. - tmeehan - 2010-09-22T10:30:02Z - cell - placental hematopoietic stem cell - - - - A hematopoietic stem cell of the placenta. This cell type is first observed E10.5 This cell type may give rise to fetal liver hematopoietic stem cells. - GOC:tfm - ISBN:978-1-60327-346-6 - @@ -29853,19 +11621,7 @@ radial glial cells acting as neural progenitors throughout life. - A hematopoietic stem cell from the aorta-gonad-mesonephros region of the developing embryo. First seen at E10.5 in mouse embryos. May give rise to fetal liver HSC. - tmeehan - 2010-09-22T10:31:49Z - cell - AGM hematopoietic stem cell - - - - A hematopoietic stem cell from the aorta-gonad-mesonephros region of the developing embryo. First seen at E10.5 in mouse embryos. May give rise to fetal liver HSC. - GOC:tfm - ISBN:978-1-60327-346-6 - @@ -29873,22 +11629,7 @@ radial glial cells acting as neural progenitors throughout life. - A progenitor cell that is capable of forming colonies of primitive erythrocytes in the blood island of the yolk sac. First arrive at E7.5 in mouse and expresses CD41. - tmeehan - 2010-09-22T10:47:28Z - EryP-CFC - inner blood island hemangioblast - cell - primitive erythroid progenitor - - - - A progenitor cell that is capable of forming colonies of primitive erythrocytes in the blood island of the yolk sac. First arrive at E7.5 in mouse and expresses CD41. - GOC:tfm - ISBN:0813817986 - PMID:20711979 - @@ -29896,19 +11637,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell located in the outermost proliferative zone of the external germinal layer that can differentiate into astroglial cells and granule cells. This cell type is glial fibrillary acidic protein-positive and NK1-positive. - tmeehan - 2010-09-22T01:40:44Z - cell - granule cell precursor - - - - A cell located in the outermost proliferative zone of the external germinal layer that can differentiate into astroglial cells and granule cells. This cell type is glial fibrillary acidic protein-positive and NK1-positive. - GOC:tfm - PMID:14745007 - @@ -29916,21 +11645,7 @@ radial glial cells acting as neural progenitors throughout life. - A keratocyte is a specialized fibroblast residing in the cornea stroma that has a flattened, dendritic cell located between the lamellae with a large flattened nucleus and lengthy processes which communicate with neighboring cells. This corneal layer, representing about 85-90% of corneal thickness, is built up from highly regular collagenous lamellae and extracellular matrix components. Keratocytes play the major role in keeping it transparent, healing its wounds, and synthesizing its components. This cell type secretes collagen I, V, VI, and keratin sulfate. - tmeehan - 2010-09-22T01:57:40Z - corneal fibroblast - corneal keratocyte - cell - keratocyte - - - - A keratocyte is a specialized fibroblast residing in the cornea stroma that has a flattened, dendritic cell located between the lamellae with a large flattened nucleus and lengthy processes which communicate with neighboring cells. This corneal layer, representing about 85-90% of corneal thickness, is built up from highly regular collagenous lamellae and extracellular matrix components. Keratocytes play the major role in keeping it transparent, healing its wounds, and synthesizing its components. This cell type secretes collagen I, V, VI, and keratin sulfate. - GOC:tfm - ISBN:978-0-7020-2958-5 - @@ -29938,21 +11653,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell of the cortical portion of the thymus. Epithelial cells in this region are required for positive selection of CD8-positive T cells. - tmeehan - 2010-09-23T03:17:12Z - BTO:0004562 - cTEC - cell - cortical thymic epithelial cell - - - - An epithelial cell of the cortical portion of the thymus. Epithelial cells in this region are required for positive selection of CD8-positive T cells. - GOC:tfm - PMID:18403190 - @@ -29960,21 +11661,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell of the medullary thymus. This cell type expresses a diverse range of tissue-specific antigens. This promiscuous gene expression is a cell-autonomous property of medullary epithelial cells and is maintained during the entire period of thymic T cell output. - tmeehan - 2010-09-23T03:17:14Z - BTO:0004563 - mTEC - cell - medullary thymic epithelial cell - - - - An epithelial cell of the medullary thymus. This cell type expresses a diverse range of tissue-specific antigens. This promiscuous gene expression is a cell-autonomous property of medullary epithelial cells and is maintained during the entire period of thymic T cell output. - GOC:tfm - PMID:18180458 - @@ -29982,21 +11669,7 @@ radial glial cells acting as neural progenitors throughout life. - A smooth muscle cell of the myometrium that enlarges and stretches during pregnancy, and contracts in response to oxytocin. - tmeehan - 2010-09-23T03:46:34Z - BTO:0004519 - myometrium smooth muscle cell - cell - myometrial cell - - - - A smooth muscle cell of the myometrium that enlarges and stretches during pregnancy, and contracts in response to oxytocin. - GOC:tfm - PMID:11429640 - @@ -30004,20 +11677,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell that lines the trabecular meshwork, which is an area of tissue in the eye located around the base of the cornea, near the ciliary body, and is responsible for draining the aqueous humor from the eye via the anterior chamber (the chamber on the front of the eye covered by the cornea). This cell may play a role in regulating intraocular pressure. - tmeehan - 2010-09-23T04:18:50Z - trabeculocyte - cell - trabecular meshwork cell - - - - A cell that lines the trabecular meshwork, which is an area of tissue in the eye located around the base of the cornea, near the ciliary body, and is responsible for draining the aqueous humor from the eye via the anterior chamber (the chamber on the front of the eye covered by the cornea). This cell may play a role in regulating intraocular pressure. - GOC:tfm - PMID:14500801 - @@ -30025,20 +11685,7 @@ radial glial cells acting as neural progenitors throughout life. - An endo-epithelial cell of the respiratory tract. - tmeehan - 2010-09-23T04:38:49Z - BTO:0004533 - airway epithelial cell - cell - respiratory epithelial cell - - - - An endo-epithelial cell of the respiratory tract. - GOC:tfm - @@ -30046,19 +11693,7 @@ radial glial cells acting as neural progenitors throughout life. - A differentiated form of a fungus produced during or as a result of an asexual or sexual reproductive process; usually a cell with a thick cell wall that stores and protects one or more nuclei. Spores may be produced in response to, and are characteristically resistant to, adverse environmental conditions. - tmeehan - 2010-10-01T09:02:42Z - cell - fungal spore - - - - A differentiated form of a fungus produced during or as a result of an asexual or sexual reproductive process; usually a cell with a thick cell wall that stores and protects one or more nuclei. Spores may be produced in response to, and are characteristically resistant to, adverse environmental conditions. - FAO:0000019 - GOC:tfm - @@ -30066,26 +11701,7 @@ radial glial cells acting as neural progenitors throughout life. - A simple columnar epithelial cell that secretes mucin. Rough endoplasmic reticulum, mitochondria, the nucleus, and other organelles are concentrated in the basal portion. The apical plasma membrane projects microvilli to increase surface area for secretion. - tmeehan - 2010-09-23T04:42:27Z - respiratory mucosa goblet cells - cell - respiratory goblet cell - - - - - A simple columnar epithelial cell that secretes mucin. Rough endoplasmic reticulum, mitochondria, the nucleus, and other organelles are concentrated in the basal portion. The apical plasma membrane projects microvilli to increase surface area for secretion. - GOC:tfm - ISBN:0721662544 - - - - - respiratory mucosa goblet cells - MP:0010863 - + @@ -30093,23 +11709,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell of an organism that does not pass on its genetic material to the organism's offspring (i.e. a non-germ line cell). - tmeehan - 2010-09-24T09:44:42Z - BTO:0001268 - FMA:72300 - WBbt:0008378 - cell - - somatic cell - - - - - A cell of an organism that does not pass on its genetic material to the organism's offspring (i.e. a non-germ line cell). - GOC:tfm - ISBN:0721662544 - + @@ -30118,24 +11718,7 @@ radial glial cells acting as neural progenitors throughout life. - A transversely striated, synctial muscle cell, formed by the fusion of myoblasts. - tmeehan - 2010-09-24T01:13:01Z - CL:0000369 - myotubule - single cell sarcomere - cell - myotube - - - - - A transversely striated, synctial muscle cell, formed by the fusion of myoblasts. - GOC:dos - GOC:tfm - ISBN:0323052908 - PMID:22274696 - + @@ -30143,21 +11726,7 @@ radial glial cells acting as neural progenitors throughout life. - A peptide hormone secreting cell that secretes growth hormone releasing hormone. - tmeehan - 2010-09-24T01:36:44Z - GHRH secreting cell - somatocrinin secreting cell - cell - growth hormone releasing hormone secreting cell - - - - A peptide hormone secreting cell that secretes growth hormone releasing hormone. - GOC:dph - GOC:tfm - @@ -30165,21 +11734,7 @@ radial glial cells acting as neural progenitors throughout life. - A hair cell of the ear that contains the organs of balance and hearing. - tmeehan - 2010-09-24T01:49:31Z - ear receptor cell - cell - ear hair cell - - - - A hair cell of the ear that contains the organs of balance and hearing. - GOC:dph - GOC:tfm - ISBN:0192801023 - @@ -30187,19 +11742,7 @@ radial glial cells acting as neural progenitors throughout life. - A giioblast cell that develops from a migratory neural crest cell. The SCP is embedded among neurons (axons) with minimal extracellular spaces separating them from nerve cell membranes and has no basal lamina. In rodents SCPs are the only cells in the Schwann cell linage that expresses Cdh19. - tmeehan - 2010-09-24T02:06:10Z - Schwann cell precursor cell - cell - Schwann cell precursor - - - - A giioblast cell that develops from a migratory neural crest cell. The SCP is embedded among neurons (axons) with minimal extracellular spaces separating them from nerve cell membranes and has no basal lamina. In rodents SCPs are the only cells in the Schwann cell linage that expresses Cdh19. - GOC:tfm - @@ -30207,21 +11750,7 @@ radial glial cells acting as neural progenitors throughout life. - A glial cell that ensheaths multiple small diameter axons in the peripheral nervous system. The non-myelinating Schwann cell is embedded among neurons (axons) with minimal extracellular spaces separating them from nerve cell membranes and has a basal lamina. Cells can survive without an axon present. These cells can de-differentiate into immature Schwann cells. - tmeehan - 2010-09-24T02:10:26Z - Schwann cell - cell - non-myelinating Schwann cell - - - - A glial cell that ensheaths multiple small diameter axons in the peripheral nervous system. The non-myelinating Schwann cell is embedded among neurons (axons) with minimal extracellular spaces separating them from nerve cell membranes and has a basal lamina. Cells can survive without an axon present. These cells can de-differentiate into immature Schwann cells. - GOC:cvs - GOC:tfm - ISBN:0721662544 - @@ -30229,22 +11758,7 @@ radial glial cells acting as neural progenitors throughout life. - A glial cell that develops from a Schwann cell precursor. The immature Schwann cell is embedded among neurons (axons) with minimal extracellular spaces separating them from nerve cell membranes and has a basal lamina. Cells can survive without an axon present. Immature Schwann cell can be found communally ensheathing large groups of axons. - tmeehan - 2010-09-24T02:10:31Z - Schwann cell - ZFA:0001725 - cell - immature Schwann cell - - - - A glial cell that develops from a Schwann cell precursor. The immature Schwann cell is embedded among neurons (axons) with minimal extracellular spaces separating them from nerve cell membranes and has a basal lamina. Cells can survive without an axon present. Immature Schwann cell can be found communally ensheathing large groups of axons. - GOC:cvs - GOC:tfm - ISBN:0721662544 - @@ -30252,21 +11766,7 @@ radial glial cells acting as neural progenitors throughout life. - A double negative thymocyte that has a T cell receptor consisting of a gamma chain containing a Vgamma2 segment, and a delta chain. This cell type is CD4- negative, CD8-negative and CD24-positive and is found in the fetal thymus. - tmeehan - 2010-10-07T02:21:07Z - fetal Vgamma2+ thymocyte - cell - NOTE: currently variable immune gene segments are not represented in the OBO Foundry. Cross-product definitions were not made as a result. Also, there are three different nomenclatures for the variable gamma segments. - immature Vgamma2-positive fetal thymocyte - - - - A double negative thymocyte that has a T cell receptor consisting of a gamma chain containing a Vgamma2 segment, and a delta chain. This cell type is CD4- negative, CD8-negative and CD24-positive and is found in the fetal thymus. - GOC:tfm - http://www.immgen.org - @@ -30274,21 +11774,7 @@ radial glial cells acting as neural progenitors throughout life. - A neurecto-epithelial cell found in the arachnoid villi of dura mater. This cell type facilitates flow of cerebrospinal fluid into the blood. - tmeehan - 2010-09-28T02:23:46Z - FMA:86588 - arachnoid cap cell - cell - meningothelial cell - - - - A neurecto-epithelial cell found in the arachnoid villi of dura mater. This cell type facilitates flow of cerebrospinal fluid into the blood. - GOC:tfm - http://www.aippg.net/forum/viewtopic.php?t=62590 - @@ -30296,21 +11782,7 @@ radial glial cells acting as neural progenitors throughout life. - An asexual spore formed by Oomycetes; formed upon fertilization of an oosphere. - tmeehan - 2010-10-01T09:22:45Z - FAO:0000039 - cell - oospore - - - - An asexual spore formed by Oomycetes; formed upon fertilization of an oosphere. - GOC:tfm - ISBN:0851988857 - SGD:clt - @@ -30318,20 +11790,7 @@ radial glial cells acting as neural progenitors throughout life. - A conidium that has only one nucleus. - tmeehan - 2010-10-01T09:26:39Z - FAO:0000025 - cell - uninucleate conidium - - - - A conidium that has only one nucleus. - GOC:tfm - SGD:clt - @@ -30339,20 +11798,7 @@ radial glial cells acting as neural progenitors throughout life. - A conidium that has more than one nucleus. - tmeehan - 2010-10-01T09:31:28Z - FAO:0000033 - cell - multinucleate conidium - - - - A conidium that has more than one nucleus. - GOC:tfm - SGD:clt - @@ -30360,19 +11806,7 @@ radial glial cells acting as neural progenitors throughout life. - A uninucleate spore formed on specialized cells or projections, sterigma, of a conidiophore head. - FAO:0000033 - cell - conidium of conidiophore head - - - - A uninucleate spore formed on specialized cells or projections, sterigma, of a conidiophore head. - GOC:tfm - PMID:9529886 - SGD:clt - @@ -30381,18 +11815,7 @@ radial glial cells acting as neural progenitors throughout life. - A macroconidium that has only one nucleus. - FAO:0000029 - cell - uninucleate macroconidium - - - - A macroconidium that has only one nucleus. - GOC:tfm - SGD:clt - @@ -30400,21 +11823,7 @@ radial glial cells acting as neural progenitors throughout life. - An oblong or round asexual spore formed from conidial chains. - BTO:0000127 - FAO:0000042 - cell - blastospore - blastoconidium - - - - An oblong or round asexual spore formed from conidial chains. - GOC:tfm - PMID:2524423 - SGD:clt - @@ -30423,18 +11832,7 @@ radial glial cells acting as neural progenitors throughout life. - A macroconidium that has more than one nucleus. - FAO:0000035 - cell - multinucleate macroconidium - - - - A macroconidium that has more than one nucleus. - GOC:tfm - SGD:clt - @@ -30442,20 +11840,7 @@ radial glial cells acting as neural progenitors throughout life. - Cylindrical spore formed by development and compartmentation of hyphae; the hyphae are often supporting blastoconidiophores. - FAO:0000041 - cell - arthrospore - arthroconidium - - - - Cylindrical spore formed by development and compartmentation of hyphae; the hyphae are often supporting blastoconidiophores. - GOC:tfm - PMID:2524423 - SGD:clt - @@ -30464,18 +11849,7 @@ radial glial cells acting as neural progenitors throughout life. - An arthroconidium that has more than one nucleus. - FAO:0000037 - cell - multinucleate arthroconidium - - - - An arthroconidium that has more than one nucleus. - GOC:tfm - SGD:clt - @@ -30484,18 +11858,7 @@ radial glial cells acting as neural progenitors throughout life. - An arthroconidium that has only one nucleus. - FAO:0000031 - cell - uninucleate arthroconidium - - - - An arthroconidium that has only one nucleus. - GOC:tfm - SGD:clt - @@ -30504,18 +11867,7 @@ radial glial cells acting as neural progenitors throughout life. - A blastoconidium that has only one nucleus. - FAO:0000030 - cell - uninucleate blastconidium - - - - A blastoconidium that has only one nucleus. - GOC:tfm - SGD:clt - @@ -30524,37 +11876,13 @@ radial glial cells acting as neural progenitors throughout life. - A blastoconidium that has more than one nucleus. - FAO:0000036 - cell - multinucleate blastoconidium - - - - A blastoconidium that has more than one nucleus. - GOC:tfm - SGD:clt - - - Obsolete. Use PO:0025017 from Plant Ontology instead. A plant cell that arises through meiosis and develops into a gametophyte. - cell - replaced_by: PO:0025017 - obsolete plant spore - true - - - - - Obsolete. Use PO:0025017 from Plant Ontology instead. A plant cell that arises through meiosis and develops into a gametophyte. - GOC:tfm - PO:0025017 - + @@ -30562,20 +11890,7 @@ radial glial cells acting as neural progenitors throughout life. - A monocyte that has characteristics of both patrolling and inflammatory monocytes. - tmeehan - 2010-10-04T10:52:03Z - cell - intermediate monocyte - - - - A monocyte that has characteristics of both patrolling and inflammatory monocytes. - GOC:tfm - PMID:20628149 - PMID:20870168 - @@ -30584,24 +11899,7 @@ radial glial cells acting as neural progenitors throughout life. - A myeloid dendritic cell found in the blood, lymph nodes, tonsil, bone marrow, and spleen that is CD141-positive (BDCA-3), XCR1-positive, and Clec9A-positive. This cell-type can cross-present antigen to CD8-positive T cells and can produce inteferon-beta. - tmeehan - 2010-10-04T02:38:58Z - cell - Markers are found in human cells. Normally they represent 3-5% of peripheral blood mDCs (human). These cells express high levels of CD283 (TLR3), are capable of producing IL-12p70 and IFN-beta upon stimulation, and inducing a TH1 response [PMCID:PMC2882828]. They are also Necl2-positive. May be human equivalent of murine CD8alpha-positive DCs. - CD141-positive myeloid dendritic cell - - - - - A myeloid dendritic cell found in the blood, lymph nodes, tonsil, bone marrow, and spleen that is CD141-positive (BDCA-3), XCR1-positive, and Clec9A-positive. This cell-type can cross-present antigen to CD8-positive T cells and can produce inteferon-beta. - GOC:dsd - GOC:tfm - PMCID:PMC2882828 - PMCID:PMC2882837 - PMID:17332250 - PMID:20628149 - + @@ -30610,22 +11908,7 @@ radial glial cells acting as neural progenitors throughout life. - A resident monocyte that is Gr-1 high, CD43-negative, CX3CR1-negative, CD115-positive, and B220-negative. - tmeehan - 2010-10-04T11:26:18Z - cell - Markers are associated with mice. The Gr epitope is used to describe this cell type is found on both Ly6c and Ly6g. However, its the Ly6c that is considered the specific marker, and thus used in the cross-product. - Gr1-high classical monocyte - - - - A resident monocyte that is Gr-1 high, CD43-negative, CX3CR1-negative, CD115-positive, and B220-negative. - GOC:tfm - PMID:20628149 - PMID:8890901 - http://www.immgen.org/index_content.html - @@ -30634,21 +11917,7 @@ radial glial cells acting as neural progenitors throughout life. - A patrolling monocyte that is CD14-low and CD16-positive. - tmeehan - 2010-10-04T12:25:42Z - non-classical monocyte, human - cell - Markers are associated with human monocytes. - CD14-low, CD16-positive monocyte - - - - A patrolling monocyte that is CD14-low and CD16-positive. - GOC:tfm - PMID:20870168 - @@ -30656,29 +11925,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD14-positive monocyte that is also CD16-positive and CCR2-negative. - tmeehan - 2010-10-04T12:49:47Z - CD16+ monocyte - cell - This cell type is compatible with the HIPC Lyoplate markers for 'CD16+ monocyte'. Markers are associated with human cells. Note that this cell type encompasses both human intermediate monocytes (CD14+, CD16-low), and human non-classical monocytes (CD14-low, CD16+). - CD14-positive, CD16-positive monocyte - - - - - A CD14-positive monocyte that is also CD16-positive and CCR2-negative. - GOC:tfm - PMID:20628149 - PMID:21937707 - PMID:22343568 - - - - - CD16+ monocyte - PMID:22343568 - + @@ -30687,19 +11934,7 @@ radial glial cells acting as neural progenitors throughout life. - An intermediate monocyte that is Gr1-positive, CD43-positive. - tmeehan - 2010-10-04T12:49:49Z - cell - Gr1-positive, CD43-positive monocyte - - - - An intermediate monocyte that is Gr1-positive, CD43-positive. - GOC:tfm - PMID:20628149 - @@ -30707,22 +11942,7 @@ radial glial cells acting as neural progenitors throughout life. - A myeloid dendritic cell found in the blood that is CD1c-positive. - tmeehan - 2010-10-04T02:39:01Z - cell - Normally represent 10-20% of peripheral blood mDCs (human). They are also CD281-positive (TLR1), CD282-positive (TLR2), CD283-positive (TLR3), CD284-positive (TLR4), CD285-positive (TLR5), CD286-positive (TLR6), CD288-positive (TLR8), and CD290-positive (TLR10) [PMID:20204387]. Upon TLR stimulation, these cells were potent producers of CXCL8 (IL-8), while producing little TNF-alpha. - CD1c-positive myeloid dendritic cell - - - - A myeloid dendritic cell found in the blood that is CD1c-positive. - GOC:dsd - GOC:tfm - PMID:20204387 - PMID:20628149 - @@ -30730,19 +11950,7 @@ radial glial cells acting as neural progenitors throughout life. - A precursor B cell that is AA4-positive, IgM-negative, CD19-positive, CD43-positive and HSA-positive. - tmeehan - 2010-10-05T10:11:38Z - cell - Fraction B/C precursor B cell - - - - A precursor B cell that is AA4-positive, IgM-negative, CD19-positive, CD43-positive and HSA-positive. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -30750,22 +11958,7 @@ radial glial cells acting as neural progenitors throughout life. - A thymocyte that has a T cell receptor consisting of a gamma chain that has as part a Vgamma3 segment, and a delta chain. This cell type is CD4- negative, CD8-negative and CD24-negative. This cell-type is found in the fetal thymus with highest numbers occurring at E17-E18. - tmeehan - 2010-10-07T02:05:46Z - mature DEC precursor - mature DETC precursor - cell - NOTE: currently variable immune gene segments are not represented in the OBO Foundry. Cross-product definitions were not made as a result. Also, there are three different nomenclatures for the variable gamma segments. - mature dendritic epithelial T cell precursor - - - - A thymocyte that has a T cell receptor consisting of a gamma chain that has as part a Vgamma3 segment, and a delta chain. This cell type is CD4- negative, CD8-negative and CD24-negative. This cell-type is found in the fetal thymus with highest numbers occurring at E17-E18. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -30773,20 +11966,7 @@ radial glial cells acting as neural progenitors throughout life. - A resting mature B cell within the Peyer's patch that is CD19-positive, B220-positive, IgM-positive, AA4-negative, CD23-positive, CD43-negative, and CD5-negative. - tmeehan - 2010-10-05T11:18:03Z - Peyers patch B cell - cell - Peyer's patch B cell - - - - A resting mature B cell within the Peyer's patch that is CD19-positive, B220-positive, IgM-positive, AA4-negative, CD23-positive, CD43-negative, and CD5-negative. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -30794,21 +11974,7 @@ radial glial cells acting as neural progenitors throughout life. - A thymocyte that has a T cell receptor consisting of a gamma chain containing Vgamma2 segment, and a delta chain. This cell type is CD4- negative, CD8-negative and CD24-negative. This cell-type is found in the fetal thymus. - tmeehan - 2010-10-07T02:24:36Z - fetal Vgamma2-positive - cell - NOTE: currently variable immune gene segments are not represented in the OBO Foundry. Cross-product definitions were not made as a result. Also, there are three different nomenclatures for the variable gamma segments. - mature Vgamma2-positive fetal thymocyte - - - - A thymocyte that has a T cell receptor consisting of a gamma chain containing Vgamma2 segment, and a delta chain. This cell type is CD4- negative, CD8-negative and CD24-negative. This cell-type is found in the fetal thymus. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -30816,18 +11982,7 @@ radial glial cells acting as neural progenitors throughout life. - A thymocyte found in the fetal thymus. - tmeehan - 2010-10-07T02:28:25Z - cell - fetal thymocyte - - - - A thymocyte found in the fetal thymus. - GOC:tfm - @@ -30836,21 +11991,7 @@ radial glial cells acting as neural progenitors throughout life. - A post-natal thymocyte expressing components of the gamma-delta T cell receptor. This cell type is always double-negative (i.e. CD4-negative, CD8-negative). - tmeehan - 2010-10-07T02:33:39Z - gammadelta thymocyte - gd thymocyte - cell - gamma-delta thymocyte - - - - A post-natal thymocyte expressing components of the gamma-delta T cell receptor. This cell type is always double-negative (i.e. CD4-negative, CD8-negative). - GOC:tfm - PMID:20725107 - @@ -30858,21 +11999,7 @@ radial glial cells acting as neural progenitors throughout life. - A double negative post-natal thymocyte that has a T cell receptor consisting of a gamma chain containing a Vgamma2 segment, and a delta chain. This cell type is CD4- negative, CD8-negative and CD24-positive. - tmeehan - 2010-10-07T02:53:44Z - Vgamma2-positive thymocyte - cell - NOTE: currently variable immune gene segments are not represented in the OBO Foundry. Cross-product definitions were not made as a result. Also, there are three different nomenclatures for the variable gamma segments. - immature Vgamma2-positive thymocyte - - - - A double negative post-natal thymocyte that has a T cell receptor consisting of a gamma chain containing a Vgamma2 segment, and a delta chain. This cell type is CD4- negative, CD8-negative and CD24-positive. - GOC:tfm - http://www.immgen.org - @@ -30880,21 +12007,7 @@ radial glial cells acting as neural progenitors throughout life. - A thymocyte that has a T cell receptor consisting of a gamma chain containing Vgamma2 segment, and a delta chain. This cell type is CD4- negative, CD8-negative and CD24-negative. This cell-type is found in the fetal thymus. - tmeehan - 2010-10-07T02:53:48Z - Vgamma2-positive - cell - NOTE: currently variable immune gene segments are not represented in the OBO Foundry. Cross-product definitions were not made as a result. Also, there are three different nomenclatures for the variable gamma segments. - mature Vgamma2-positive thymocyte - - - - A thymocyte that has a T cell receptor consisting of a gamma chain containing Vgamma2 segment, and a delta chain. This cell type is CD4- negative, CD8-negative and CD24-negative. This cell-type is found in the fetal thymus. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -30902,21 +12015,7 @@ radial glial cells acting as neural progenitors throughout life. - A double negative post-natal thymocyte that has a T cell receptor consisting of a gamma chain containing a Vgamma2 segment, and a delta chain. This cell type is CD4- negative, CD8-negative and CD24-positive. - tmeehan - 2010-10-07T02:59:05Z - Vgamma2-negative thymocyte - cell - NOTE: currently variable immune gene segments are not represented in the OBO Foundry. Cross-product definitions were not made as a result. Also, there are three different nomenclatures for the variable gamma segments. - immature Vgamma2-negative thymocyte - - - - A double negative post-natal thymocyte that has a T cell receptor consisting of a gamma chain containing a Vgamma2 segment, and a delta chain. This cell type is CD4- negative, CD8-negative and CD24-positive. - GOC:tfm - http://www.immgen.org - @@ -30924,21 +12023,7 @@ radial glial cells acting as neural progenitors throughout life. - A thymocyte that has a T cell receptor consisting of a gamma chain containing Vgamma2 segment, and a delta chain. This cell type is CD4- negative, CD8-negative and CD24-negative. This cell-type is found in the fetal thymus. - tmeehan - 2010-10-07T02:59:08Z - Vgamma2-negative - cell - NOTE: currently variable immune gene segments are not represented in the OBO Foundry. Cross-product definitions were not made as a result. Also, there are three different nomenclatures for the variable gamma segments. - mature Vgamma2-negative thymocyte - - - - A thymocyte that has a T cell receptor consisting of a gamma chain containing Vgamma2 segment, and a delta chain. This cell type is CD4- negative, CD8-negative and CD24-negative. This cell-type is found in the fetal thymus. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -30946,22 +12031,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell that is found in the periacinar space of the exocrine pancreas and in perivascular and periductal regions of the pancreas, and has long cytoplasmic processes that encircle the base of the acinus. Expresses several intermediate filament proteins including vimentin and nestin. Shares many of the characteristics of hepatatic stellate cells, but not stellate cells of the central nervous system. Upon activation, this cell type undergoes morphological and gene expression changes that make the cell suggestive of being a type of myofibroblast. - tmeehan - 2010-11-10T09:40:33Z - PaSC - pancreas stellate cell - cell - pancreatic stellate cell - - - - A cell that is found in the periacinar space of the exocrine pancreas and in perivascular and periductal regions of the pancreas, and has long cytoplasmic processes that encircle the base of the acinus. Expresses several intermediate filament proteins including vimentin and nestin. Shares many of the characteristics of hepatatic stellate cells, but not stellate cells of the central nervous system. Upon activation, this cell type undergoes morphological and gene expression changes that make the cell suggestive of being a type of myofibroblast. - GOC:mah - GOC:tfm - PMID:17200706 - @@ -30969,20 +12039,7 @@ radial glial cells acting as neural progenitors throughout life. - A gamma-delta receptor that expresses Vgamma1.1 but does not express Vdelta6.3 chains in the T-cell receptor. - tmeehan - 2010-10-07T03:07:44Z - Vg1.1-positive, Vd6.3-negative T cell - cell - Vgamma1.1-positive, Vdelta6.3-negative thymocyte - - - - A gamma-delta receptor that expresses Vgamma1.1 but does not express Vdelta6.3 chains in the T-cell receptor. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -30990,20 +12047,7 @@ radial glial cells acting as neural progenitors throughout life. - A gamma-delta receptor that expresses Vgamma1.1-Vdelta6.3 chains in the T-cell receptor. - tmeehan - 2010-10-07T03:03:00Z - Vg1.1+Vd6.3+ T cell - cell - Vgamma1.1-positive, Vdelta6.3-positive thymocyte - - - - A gamma-delta receptor that expresses Vgamma1.1-Vdelta6.3 chains in the T-cell receptor. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -31011,20 +12055,7 @@ radial glial cells acting as neural progenitors throughout life. - A Vgamma1.1-positive, Vdelta6.3-negative thymocyte that is CD24-negative. - tmeehan - 2010-10-07T03:10:32Z - cell - mature Vg1.1-positive, Vd6.3-negative T cell - mature Vgamma1.1-positive, Vdelta6.3-negative thymocyte - - - - A Vgamma1.1-positive, Vdelta6.3-negative thymocyte that is CD24-negative. - GOC:tfm - http://www.immgen.org - @@ -31032,20 +12063,7 @@ radial glial cells acting as neural progenitors throughout life. - A Vgamma1.1-positive, Vdelta6.3-negative thymocyte that is CD24-positive. - tmeehan - 2010-10-07T03:10:35Z - cell - immature Vg1.1-positive, Vd6.3-negative T cell - immature Vgamma1.1-positive, Vdelta6.3-negative thymocyte - - - - A Vgamma1.1-positive, Vdelta6.3-negative thymocyte that is CD24-positive. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -31053,20 +12071,7 @@ radial glial cells acting as neural progenitors throughout life. - A Vgamma1.1-positive, Vdelta6.3-positive thymocyte that is CD24-positive. - tmeehan - 2010-10-07T03:10:39Z - immature Vg1.1+Vd6.3+ T cell - cell - immature Vgamma1.1-positive, Vdelta6.3-positive thymocyte - - - - A Vgamma1.1-positive, Vdelta6.3-positive thymocyte that is CD24-positive. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -31074,20 +12079,7 @@ radial glial cells acting as neural progenitors throughout life. - A Vgamma1.1-positive, Vdelta6.3-positive thymocyte that is CD24-negative. - tmeehan - 2010-10-07T03:10:41Z - mature Vg1.1+Vd6.3+ T cell - cell - mature Vgamma1.1-positive, Vdelta6.3-positive thymocyte - - - - A Vgamma1.1-positive, Vdelta6.3-positive thymocyte that is CD24-negative. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -31095,18 +12087,7 @@ radial glial cells acting as neural progenitors throughout life. - An immature or mature cell of the first erythroid lineage to arise during embryonic development. - tmeehan - 2010-10-12T11:22:41Z - cell - primitive erythroid lineage cell - - - - An immature or mature cell of the first erythroid lineage to arise during embryonic development. - GOC:tfm - @@ -31114,20 +12095,7 @@ radial glial cells acting as neural progenitors throughout life. - A pluripotent cell in the yolk sac that can give rise to mesenchymal cells including erythrocytes and endothelial cells. - tmeehan - 2010-10-12T12:21:16Z - cell - hemangioblast - - - - A pluripotent cell in the yolk sac that can give rise to mesenchymal cells including erythrocytes and endothelial cells. - GOC:tfm - ISBN:0813817986 - PMID:11495698 - @@ -31135,21 +12103,7 @@ radial glial cells acting as neural progenitors throughout life. - A T cell that expresses a T cell receptor complex and has completed T cell selection. - tmeehan - 2010-10-12T01:56:15Z - CD3e-positive T cell - mature T-cell - cell - CD3epsilon T cell - mature T cell - - - - A T cell that expresses a T cell receptor complex and has completed T cell selection. - GOC:tfm - @@ -31157,21 +12111,7 @@ radial glial cells acting as neural progenitors throughout life. - A T cell that has not completed T cell selection. - tmeehan - 2010-10-12T01:56:17Z - BTO:0001372 - CALOHA:TS-1042 - immature T-cell - cell - immature T cell - - - - A T cell that has not completed T cell selection. - GOC:tfm - @@ -31180,21 +12120,7 @@ radial glial cells acting as neural progenitors throughout life. - A reticulocyte that retains the nucleus and other organelles. Found in birds, fish, amphibians and reptiles. - tmeehan - 2010-10-15T09:24:05Z - cell - nucleated reticulocyte - - - - A reticulocyte that retains the nucleus and other organelles. Found in birds, fish, amphibians and reptiles. - GOC:tfm - PMID:18182572 - PMID:9011180 - PMID:9046052 - @@ -31203,22 +12129,7 @@ radial glial cells acting as neural progenitors throughout life. - A reticulocyte lacking a nucleus and showing a basophilic reticulum under vital staining due to the presence of ribosomes. - tmeehan - 2010-10-15T09:24:08Z - CALOHA:TS-0864 - FMA:66785 - cell - enucleated reticulocyte - - - - A reticulocyte lacking a nucleus and showing a basophilic reticulum under vital staining due to the presence of ribosomes. - GOC:tfm - ISBN:0-12203-052-4 - ISBN:0721601464 - @@ -31226,20 +12137,7 @@ radial glial cells acting as neural progenitors throughout life. - A DN2 thymocyte that is Kit-hi. - tmeehan - 2010-10-21T10:12:05Z - cell - Observed in mice. - DN2a thymocyte - - - - A DN2 thymocyte that is Kit-hi. - GOC:tfm - PMID:20595614 - @@ -31247,20 +12145,7 @@ radial glial cells acting as neural progenitors throughout life. - A DN2 thymocyte that is Kit-low. - tmeehan - 2010-10-21T10:12:08Z - cell - Observed in mice. - DN2b thymocyte - - - - A DN2 thymocyte that is Kit-low. - GOC:tfm - PMID:20595614 - @@ -31268,24 +12153,7 @@ radial glial cells acting as neural progenitors throughout life. - A pro-T cell that is lin-negative, CD25-negative, CD127-negative, CD44-positive and kit-positive. - tmeehan - 2010-10-21T01:16:24Z - ETP - preT.ETP.Th - cell - ETPs are reportedly CD1a-negative, CD4-negative, CD7-positive, CD8a-negative, CD8b-negative, CD33-low, CD34-high, CD38-low, CD45RA-positive, and CD45RO-negative. - early T lineage precursor - - - - - A pro-T cell that is lin-negative, CD25-negative, CD127-negative, CD44-positive and kit-positive. - GOC:dsd - GOC:tfm - PMID:16551251 - http://www.immgen.org/index_content.html - + @@ -31293,20 +12161,7 @@ radial glial cells acting as neural progenitors throughout life. - A mature natural killer cell that is CD11b-positive and CD27-positive. - tmeehan - 2010-10-25T03:07:59Z - cell - A natural killer cell that is NK1.1-positive, CD11b-positive, and CD27-positive. - CD11b-positive, CD27-positive natural killer cell - - - - A mature natural killer cell that is CD11b-positive and CD27-positive. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -31314,20 +12169,7 @@ radial glial cells acting as neural progenitors throughout life. - A double-positive, alpha-beta thymocyte that is small and not proliferating. - tmeehan - 2010-10-21T01:59:06Z - T.DP.sm.Th - cell - resting double-positive thymocyte - - - - A double-positive, alpha-beta thymocyte that is small and not proliferating. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -31335,21 +12177,7 @@ radial glial cells acting as neural progenitors throughout life. - A double-positive thymocyte that is large (i.e. has a high forward scatter signal in flow cytometry) and is actively proliferating. - tmeehan - 2010-10-21T01:59:11Z - T.DPb.Th - activated double-positive thymocyte - cell - double-positive blast - - - - A double-positive thymocyte that is large (i.e. has a high forward scatter signal in flow cytometry) and is actively proliferating. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -31357,20 +12185,7 @@ radial glial cells acting as neural progenitors throughout life. - A double-positive thymocyte that is CD69-positive and has begun positive selection. - tmeehan - 2010-10-21T02:11:52Z - T.DP69+.Th - cell - CD69-positive double-positive thymocyte - - - - A double-positive thymocyte that is CD69-positive and has begun positive selection. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -31378,20 +12193,7 @@ radial glial cells acting as neural progenitors throughout life. - A double-positive thymocyte that is undergoing positive selection, has high expression of the alpha-beta T cell receptor, is CD69-positive, and is in the process of down regulating the CD4 co-receptor. - tmeehan - 2010-10-21T02:29:19Z - T.4int8+.Th - cell - CD4-intermediate, CD8-positive double-positive thymocyte - - - - A double-positive thymocyte that is undergoing positive selection, has high expression of the alpha-beta T cell receptor, is CD69-positive, and is in the process of down regulating the CD4 co-receptor. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -31399,20 +12201,7 @@ radial glial cells acting as neural progenitors throughout life. - A double-positive thymocyte that is undergoing positive selection, has high expression of the alpha-beta T cell receptor, is CD69-positive, and is in the process of down regulating the CD4 co-receptor. - tmeehan - 2010-10-21T02:29:23Z - T.4int8+.th - cell - CD4-positive, CD8-intermediate double-positive thymocyte - - - - A double-positive thymocyte that is undergoing positive selection, has high expression of the alpha-beta T cell receptor, is CD69-positive, and is in the process of down regulating the CD4 co-receptor. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -31420,22 +12209,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD4-positive, CD8-negative thymocyte that is CD24-positive and expresses high levels of the alpha-beta T cell receptor. - tmeehan - 2010-10-21T02:43:52Z - CD24-positive, CD4 single-positive semimature thymocyte - T.4SP24int.Th - cell - Described in the immgene database as being CD24-intermediate. - CD24-positive, CD4 single-positive thymocyte - - - - A CD4-positive, CD8-negative thymocyte that is CD24-positive and expresses high levels of the alpha-beta T cell receptor. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -31443,21 +12217,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD4-positive, CD8-negative thymocyte that expresses high levels of the alpha-beta T cell receptor and is CD69-positive. - tmeehan - 2010-10-21T02:46:02Z - T.4SP69+.Th - intermediate CD4-single-positive - cell - CD69-positive, CD4-positive single-positive thymocyte - - - - A CD4-positive, CD8-negative thymocyte that expresses high levels of the alpha-beta T cell receptor and is CD69-positive. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -31465,22 +12225,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD8-positive, CD4-negative thymocyte that is CD24-positive and expresses high levels of the alpha-beta T cell receptor. - tmeehan - 2010-10-21T02:59:10Z - CD24-positive, CD8 single-positive semimature thymocyte - T.8SP24int.Th - cell - Described in the immgene database as being CD24-intermediate. - CD24-positive, CD8 single-positive thymocyte - - - - A CD8-positive, CD4-negative thymocyte that is CD24-positive and expresses high levels of the alpha-beta T cell receptor. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -31488,21 +12233,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD4-positive, CD8-negative thymocyte that expresses high levels of the alpha-beta T cell receptor and is CD69-positive. - tmeehan - 2010-10-21T02:59:14Z - T.8SP69+.Th - intermediate CD8-single-positive - cell - CD69-positive, CD8-positive single-positive thymocyte - - - - A CD4-positive, CD8-negative thymocyte that expresses high levels of the alpha-beta T cell receptor and is CD69-positive. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -31510,20 +12241,7 @@ radial glial cells acting as neural progenitors throughout life. - A mature CD4-positive, CD8-negative alpha-beta T cell found in the thymus that is CD24-low and has high expression of the T cell receptor. - tmeehan - 2010-10-21T03:31:19Z - cell - T.4SP24-.Th - mature CD4 single-positive thymocyte - - - - A mature CD4-positive, CD8-negative alpha-beta T cell found in the thymus that is CD24-low and has high expression of the T cell receptor. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -31531,20 +12249,7 @@ radial glial cells acting as neural progenitors throughout life. - A mature CD8-positive, CD4-negative alpha-beta T cell found in the thymus that is CD24-low and has high expression of the T cell receptor. - tmeehan - 2010-10-21T03:51:50Z - T.8SP24-.Th - cell - mature CD8 single-positive thymocyte - - - - A mature CD8-positive, CD4-negative alpha-beta T cell found in the thymus that is CD24-low and has high expression of the T cell receptor. - GOC:tfm - http:www.immgen.org/index_content.html - @@ -31552,21 +12257,7 @@ radial glial cells acting as neural progenitors throughout life. - A mature NK cell that is NK1.1-positive. - tmeehan - 2010-10-25T03:18:04Z - NK.sp - NK1.1-positive NK cell - cell - Note: Nk1.1 expression is restricted to C57BL strains of laboratory mice. - NK1.1-positive natural killer cell - - - - A mature NK cell that is NK1.1-positive. - GOC:tfm - @@ -31574,20 +12265,7 @@ radial glial cells acting as neural progenitors throughout life. - A NK1.1-positive T cell that is NKGA2-positive. - tmeehan - 2010-10-25T03:31:09Z - NK.G2A+.SP - cell - NKGA2-positive natural killer cell - - - - A NK1.1-positive T cell that is NKGA2-positive. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -31595,20 +12273,7 @@ radial glial cells acting as neural progenitors throughout life. - A NK1.1-positive T cell that is Ly49D-positive. - tmeehan - 2010-10-25T03:36:19Z - NK.49D+.Sp - cell - Ly49D-positive natural killer cell - - - - A NK1.1-positive T cell that is Ly49D-positive. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -31616,20 +12281,7 @@ radial glial cells acting as neural progenitors throughout life. - A NK1.1-positive T cell that is CD94-positive. - tmeehan - 2010-10-25T03:36:28Z - NK.94+.Sp - cell - CD94-positive natural killer cell - - - - A NK1.1-positive T cell that is CD94-positive. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -31638,21 +12290,7 @@ radial glial cells acting as neural progenitors throughout life. - A NK1.1-positive T cell that is CD94-negative and Ly49Cl-negative. - tmeehan - 2010-10-25T03:56:21Z - CD94- Ly49I-negative NK cell - NK.49Cl-94-.Sp - cell - CD94-negative, Ly49CI-negative natural killer cell - - - - A NK1.1-positive T cell that is CD94-negative and Ly49Cl-negative. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -31660,21 +12298,7 @@ radial glial cells acting as neural progenitors throughout life. - A NK1.1-positive T cell that is Ly49Cl-positive. - tmeehan - 2010-10-25T03:36:38Z - Ly49I-positive NK cell - NK.49Cl+.Sp - cell - Ly49CI-positive natural killer cell - - - - A NK1.1-positive T cell that is Ly49Cl-positive. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -31682,20 +12306,7 @@ radial glial cells acting as neural progenitors throughout life. - A NK1.1-positive T cell that is Ly49H-positive. - tmeehan - 2010-10-25T03:36:43Z - LyH49H-positive - cell - Ly49H-positive natural killer cell - - - - A NK1.1-positive T cell that is Ly49H-positive. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -31703,20 +12314,7 @@ radial glial cells acting as neural progenitors throughout life. - A NK1.1-positive T cell that is Ly49D-negative. - tmeehan - 2010-10-25T03:39:02Z - NK.49D-.Sp - cell - Ly49D-negative natural killer cell - - - - A NK1.1-positive T cell that is Ly49D-negative. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -31724,21 +12322,7 @@ radial glial cells acting as neural progenitors throughout life. - A NK1.1-positive T cell that is Ly49Cl-negative. - tmeehan - 2010-10-25T03:52:04Z - Ly49I-negative NK cell - NK.49Cl-.Sp - cell - Ly49CI-negative natural killer cell - - - - A NK1.1-positive T cell that is Ly49Cl-negative. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -31746,20 +12330,7 @@ radial glial cells acting as neural progenitors throughout life. - A NK1.1-positive T cell that is CD94-negative. - tmeehan - 2010-10-25T03:54:18Z - NK.94-.Sp - cell - CD94-negative natural killer cell - - - - A NK1.1-positive T cell that is CD94-negative. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -31767,20 +12338,7 @@ radial glial cells acting as neural progenitors throughout life. - A NK1.1-positive T cell that is Ly49H-negative. - tmeehan - 2010-10-25T03:42:42Z - LyH49H-negative - cell - Ly49H-negative natural killer cell - - - - A NK1.1-positive T cell that is Ly49H-negative. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -31789,20 +12347,7 @@ radial glial cells acting as neural progenitors throughout life. - A NK1.1-positive T cell that is CD94-positive and Ly49Cl-positive. - tmeehan - 2010-10-25T03:56:27Z - NK.49Cl+94+.Sp - cell - CD94-positive Ly49CI-positive natural killer cell - - - - A NK1.1-positive T cell that is CD94-positive and Ly49Cl-positive. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -31810,20 +12355,7 @@ radial glial cells acting as neural progenitors throughout life. - A specialized hair cell that has an elongated kinocilium upon which an otolith accretes. The tether cell then anchors the otolith in place. - tmeehan - 2010-11-10T01:41:00Z - cell - tether cell - - - - A specialized hair cell that has an elongated kinocilium upon which an otolith accretes. The tether cell then anchors the otolith in place. - GOC:cvs - GOC:tfm - PMID:9398434 - @@ -31831,22 +12363,7 @@ radial glial cells acting as neural progenitors throughout life. - A multi-fate stem cell that is the source of cells for growth of the mammary gland during puberty and gestation. This cell type gives rise to both the luminal and myoepithelial cell types of the gland, and have been shown to have the ability to regenerate the entire organ in mice. This cell type also plays an important role in carcinogenesis of the breast. This cell type is Lin-, CD24-positive, CD29-hi. - tmeehan - 2010-11-10T01:46:51Z - cell - mammary stem cell - - - - A multi-fate stem cell that is the source of cells for growth of the mammary gland during puberty and gestation. This cell type gives rise to both the luminal and myoepithelial cell types of the gland, and have been shown to have the ability to regenerate the entire organ in mice. This cell type also plays an important role in carcinogenesis of the breast. This cell type is Lin-, CD24-positive, CD29-hi. - GOC:hjd - GOC:tfm - PMID:15987436 - PMID:16397499 - PMID:17851544 - @@ -31854,19 +12371,7 @@ radial glial cells acting as neural progenitors throughout life. - The cell type from which oligodendrocytes develop. This cell originates from multiple structures within the developing brain including the medial ganglion eminence and the lateral ganglionic eminence. These cells migrate throughout the central nervous system and persist into adulthood where they play an important role in remyelination of injured neurons. - tmeehan - 2010-11-10T02:51:34Z - cell - oligodendrocyte precursor cell - - - - The cell type from which oligodendrocytes develop. This cell originates from multiple structures within the developing brain including the medial ganglion eminence and the lateral ganglionic eminence. These cells migrate throughout the central nervous system and persist into adulthood where they play an important role in remyelination of injured neurons. - GOC:tfm - PMID:20142420 - @@ -31874,21 +12379,7 @@ radial glial cells acting as neural progenitors throughout life. - Cd4-negative, CD8_alpha-negative, CD11b-positive dendritic cell is a conventional dendritic cell that is CD11b-positive, CD4-negative, CD8_alpha-negative and is CD205-positive. - tmeehan - 2010-11-22T01:10:28Z - DC.8-4-11b+ - spleen double-negative dendritic cell - cell - Cd4-negative, CD8_alpha-negative, CD11b-positive dendritic cell - - - - Cd4-negative, CD8_alpha-negative, CD11b-positive dendritic cell is a conventional dendritic cell that is CD11b-positive, CD4-negative, CD8_alpha-negative and is CD205-positive. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -31896,20 +12387,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD11c-low plasmacytoid dendritic cell that is CD8alpha-negative and CD4-positive. - tmeehan - 2010-11-22T01:27:37Z - DC.pDC.8- - cell - CD8_alpha-negative plasmactyoid dendritic cell - - - - A CD11c-low plasmacytoid dendritic cell that is CD8alpha-negative and CD4-positive. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -31917,20 +12395,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD11c-low plasmacytoid dendritic cell that is CD8alpha-positive and CD4-positive. - tmeehan - 2010-11-22T01:23:07Z - DC.pDC.8+ - cell - CD8_alpha-positive plasmactyoid dendritic cell - - - - A CD11c-low plasmacytoid dendritic cell that is CD8alpha-positive and CD4-positive. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -31939,19 +12404,7 @@ radial glial cells acting as neural progenitors throughout life. - A Langerhans cell that is in the epidermis and is CD45-positive, MHCII-positive, and CD11b-positive. - tmeehan - 2010-11-22T03:57:57Z - cell - epidermal Langerhans cell - - - - A Langerhans cell that is in the epidermis and is CD45-positive, MHCII-positive, and CD11b-positive. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -31960,19 +12413,7 @@ radial glial cells acting as neural progenitors throughout life. - A dermal dendritic cell that is langerin-positive, CD103-positive, and CD11b-negative. - tmeehan - 2010-11-22T04:06:22Z - cell - langerin-positive dermal dendritic cell - - - - A dermal dendritic cell that is langerin-positive, CD103-positive, and CD11b-negative. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -31980,37 +12421,7 @@ radial glial cells acting as neural progenitors throughout life. - - - - - - - - - - - - - - - - - - - A dermal dendritic cell that is langerin-negative, CD103-negative, and CD11b-positive. - tmeehan - 2010-11-22T04:09:44Z - cell - langerin-negative dermal dendritic cell - - - - - A dermal dendritic cell that is langerin-negative, CD103-negative, and CD11b-positive. - GOC:tfm - http://www.immgen.org/index_content.html - + @@ -32018,21 +12429,7 @@ radial glial cells acting as neural progenitors throughout life. - A conventional thymic dendritic cell that is CD8alpha-negative. - tmeehan - 2010-11-23T10:58:53Z - DC.8-.Th - cell - CD8alpha-negative thymic conventional dendritic cell - - - - A conventional thymic dendritic cell that is CD8alpha-negative. - GOC:tfm - PMID:19273629 - http://www.immgen.org/index_content.html - @@ -32041,19 +12438,7 @@ radial glial cells acting as neural progenitors throughout life. - A conventional dendritic cell that is CD103-positive. This cell type is usually found in non-lymphoid tissue. - tmeehan - 2010-11-23T01:32:43Z - cell - CD103-positive dendritic cell - - - - A conventional dendritic cell that is CD103-positive. This cell type is usually found in non-lymphoid tissue. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -32063,19 +12448,7 @@ radial glial cells acting as neural progenitors throughout life. - A F4/80-negative dendritic cell located in adipose tissue. - tmeehan - 2010-11-23T01:38:21Z - cell - adipose dendritic cell - - - - A F4/80-negative dendritic cell located in adipose tissue. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -32083,20 +12456,7 @@ radial glial cells acting as neural progenitors throughout life. - An adipose dendritic cell that is SIRPa-positive. - tmeehan - 2010-11-23T01:40:44Z - DC.SIRPa+.Ad - cell - SIRPa-positive adipose dendritic cell - - - - An adipose dendritic cell that is SIRPa-positive. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -32104,20 +12464,7 @@ radial glial cells acting as neural progenitors throughout life. - An adipose dendritic cell that is SIRPa-negative. - tmeehan - 2010-11-23T01:40:46Z - DC.SIRPa-.Ad - cell - SIRPa-negative adipose dendritic cell - - - - An adipose dendritic cell that is SIRPa-negative. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -32125,19 +12472,7 @@ radial glial cells acting as neural progenitors throughout life. - A conventional dendritic cell that expresses CD11b (ITGAM). - tmeehan - 2010-11-23T01:50:05Z - cell - CD11b-positive dendritic cell - - - - A conventional dendritic cell that expresses CD11b (ITGAM). - GOC:tfm - http://www.immgen.org/index_content.html - @@ -32145,20 +12480,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD11b-positive dendritic cell located in the serosal portion of the small intestine epithelium. This cell type is CD45-positive, MHC-II-positive, CD11c-low, CD103-negative. - tmeehan - 2010-11-23T02:00:21Z - DC.11cloSer.SI - cell - small intestine serosal dendritic cell - - - - A CD11b-positive dendritic cell located in the serosal portion of the small intestine epithelium. This cell type is CD45-positive, MHC-II-positive, CD11c-low, CD103-negative. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -32166,20 +12488,7 @@ radial glial cells acting as neural progenitors throughout life. - A myeloid suppressor cell that is Gr1-high and CD11c-negative. - tmeehan - 2010-11-23T02:15:12Z - MDS.Gr1hi - cell - Gr1-high myeloid suppressor cell - - - - A myeloid suppressor cell that is Gr1-high and CD11c-negative. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -32187,20 +12496,7 @@ radial glial cells acting as neural progenitors throughout life. - A myeloid suppressor cell that is Gr1-low and CD11c-positive. - tmeehan - 2010-11-23T02:19:43Z - MDS.Gr1lo - cell - Gr1-low myeloid suppressor cell - - - - A myeloid suppressor cell that is Gr1-low and CD11c-positive. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -32208,20 +12504,7 @@ radial glial cells acting as neural progenitors throughout life. - Gr1-high monocyte that lacks MHC-II receptor complex. - tmeehan - 2010-11-23T03:27:12Z - Mo.6C+II- - cell - MHC-II-negative classical monocyte - - - - Gr1-high monocyte that lacks MHC-II receptor complex. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -32229,20 +12512,7 @@ radial glial cells acting as neural progenitors throughout life. - Gr1-high monocyte that has a MHC-II receptor complex. - tmeehan - 2010-11-23T03:30:21Z - Mo.6c+II - cell - MHC-II-positive classical monocyte - - - - Gr1-high monocyte that has a MHC-II receptor complex. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -32250,20 +12520,7 @@ radial glial cells acting as neural progenitors throughout life. - Gr1-low non-classical monocyte that lacks expression of a MHC-II complex. - tmeehan - 2010-11-23T03:38:15Z - Mo.6C-II- - cell - MHC-II-negative non-classical monocyte - - - - Gr1-low non-classical monocyte that lacks expression of a MHC-II complex. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -32271,20 +12528,7 @@ radial glial cells acting as neural progenitors throughout life. - Gr1-low non-classical monocyte that has low to intermediate expression of the MHC-II complex. - tmeehan - 2010-11-23T03:47:53Z - Mo.6C-IIint - cell - MHC-II-low non-classical monocyte - - - - Gr1-low non-classical monocyte that has low to intermediate expression of the MHC-II complex. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -32292,20 +12536,7 @@ radial glial cells acting as neural progenitors throughout life. - Gr1-low non-classical monocyte that has high surface expression of a MHC-II complex. - tmeehan - 2010-11-23T03:47:55Z - Mo.6C-II+ - cell - MHC-II-high non-classical monocyte - - - - Gr1-low non-classical monocyte that has high surface expression of a MHC-II complex. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -32313,19 +12544,7 @@ radial glial cells acting as neural progenitors throughout life. - A MHC-II-negative classical monocyte located in lymphoid tissue that is F4/80-positive, CD11c-negative, and CD11b-high. - tmeehan - 2010-11-23T04:00:52Z - cell - lymphoid MHC-II-negative classical monocyte - - - - A MHC-II-negative classical monocyte located in lymphoid tissue that is F4/80-positive, CD11c-negative, and CD11b-high. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -32334,19 +12553,7 @@ radial glial cells acting as neural progenitors throughout life. - A MHC-II-negative classical monocyte located in lymphoid tissue that is F4/80-positive, CD11c-intermediate, and CD11b-high. - tmeehan - 2010-11-23T04:09:09Z - cell - lymphoid MHC-II-negative non-classical monocyte - - - - A MHC-II-negative classical monocyte located in lymphoid tissue that is F4/80-positive, CD11c-intermediate, and CD11b-high. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -32355,21 +12562,7 @@ radial glial cells acting as neural progenitors throughout life. - A tissue-resident macrophage located in the bone marrow. This cell type is B220-negative, CD3e-negative, Ly-6C-negative, CD115-positive, F4/80-positive. - tmeehan - 2010-11-23T04:19:25Z - BTO:0004732 - cell - MF.BM - bone marrow macrophage - - - - A tissue-resident macrophage located in the bone marrow. This cell type is B220-negative, CD3e-negative, Ly-6C-negative, CD115-positive, F4/80-positive. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -32377,18 +12570,7 @@ radial glial cells acting as neural progenitors throughout life. - A macrophage located in adipose tissue that is CD45-positive, CD11c-positive, and SIRPa-positive. - tmeehan - 2010-11-23T04:31:28Z - cell - adipose macrophage - - - - A macrophage located in adipose tissue that is CD45-positive, CD11c-positive, and SIRPa-positive. - GOC:tfm - @@ -32396,20 +12578,7 @@ radial glial cells acting as neural progenitors throughout life. - An adipose macrophage that does not express F4/80but is MHC-II-positive. This cell type exhibits autofluorescence under typical flow cyometry conditions. - tmeehan - 2010-11-23T04:40:50Z - MF.Autofl.Ad - cell - F4/80-negative adipose macrophage - - - - An adipose macrophage that does not express F4/80but is MHC-II-positive. This cell type exhibits autofluorescence under typical flow cyometry conditions. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -32417,20 +12586,7 @@ radial glial cells acting as neural progenitors throughout life. - An adipose macrophage that does not express MHC-II but is F4/80-positive. - tmeehan - 2010-11-23T04:35:53Z - MF.F480+.Ad - cell - F4/80-positive adipose macrophage - - - - An adipose macrophage that does not express MHC-II but is F4/80-positive. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -32438,20 +12594,7 @@ radial glial cells acting as neural progenitors throughout life. - A goblet cell located in the nasal epithelium. - tmeehan - 2010-12-03T03:03:02Z - MP:0002262 - cell - nasal mucosa goblet cell - - - - A goblet cell located in the nasal epithelium. - GOC:cjm - GOC:tfm - @@ -32460,20 +12603,7 @@ radial glial cells acting as neural progenitors throughout life. - The flattened smooth myoepithelial cells of mesodermal origin that lie just outside the basal lamina of the seminiferous tubule. - tmeehan - 2010-12-03T03:11:48Z - cell - peritubular myoid cell - - - - The flattened smooth myoepithelial cells of mesodermal origin that lie just outside the basal lamina of the seminiferous tubule. - GOC:cjm - GOC:tfm - MP:0006420 - @@ -32481,20 +12611,7 @@ radial glial cells acting as neural progenitors throughout life. - A melanocyte that produces pigment in the dermis. - tmeehan - 2010-12-03T03:17:05Z - cell - dermal melanocyte - - - - A melanocyte that produces pigment in the dermis. - GOC:cjm - GOC:tfm - MP:0009386 - @@ -32503,19 +12620,7 @@ radial glial cells acting as neural progenitors throughout life. - A melanocyte that produces pigment within the hair follicle. - tmeehan - 2010-12-03T03:17:09Z - cell - hair follicle melanocyte - - - - A melanocyte that produces pigment within the hair follicle. - GOC:tfm - MP:0004381 - @@ -32523,20 +12628,7 @@ radial glial cells acting as neural progenitors throughout life. - A melanocyte that produces pigment in the epithelium. - tmeehan - 2010-12-03T03:17:14Z - cell - The text defintion reference to the MP term appears to reference an epidermal melanocyte term. This term represents any melanocyte in any epithelium. - epithelial melanocyte - - - - A melanocyte that produces pigment in the epithelium. - GOC:tfm - MP:0009388 - @@ -32544,20 +12636,7 @@ radial glial cells acting as neural progenitors throughout life. - - A melanocyte of the retina. This cell type is distinct from pigmented retinal epithelium. - tmeehan - 2010-12-03T03:25:32Z - cell - retinal melanocyte - - - - A melanocyte of the retina. This cell type is distinct from pigmented retinal epithelium. - GOC:tfm - MP:0010190 - @@ -32567,19 +12646,7 @@ radial glial cells acting as neural progenitors throughout life. - A melanocyte located between the epithelial marginal cell layer and the mesodermal basal cell layer within the intrastrial space; the predominant cellular component of the electrogenic machinery that generates an endocochlear potential (80-100 mV) . - tmeehan - 2010-12-03T03:29:15Z - cell - strial intermediate cell - - - - A melanocyte located between the epithelial marginal cell layer and the mesodermal basal cell layer within the intrastrial space; the predominant cellular component of the electrogenic machinery that generates an endocochlear potential (80-100 mV) . - GOC:tfm - MP:0000048 - @@ -32587,19 +12654,7 @@ radial glial cells acting as neural progenitors throughout life. - A neuronal receptor that respond to mechanical pressure or distortion in the skin. - tmeehan - 2010-12-06T02:53:30Z - cell - cutaneous/subcutaneous mechanoreceptor cell - - - - A neuronal receptor that respond to mechanical pressure or distortion in the skin. - GOC:tfm - MP:0000973 - @@ -32607,21 +12662,7 @@ radial glial cells acting as neural progenitors throughout life. - A trophoblast cell that has a large volume of cytoplasm, is polyploidy and is usually mononuclear but is also occasionally multi-nucleate. This cell type is important in establishing maternal physiology and remodeling of the vasculature of the placenta. - tmeehan - 2010-12-06T02:55:24Z - giant trophoblast cell - cell - trophoblast giant cell - - - - A trophoblast cell that has a large volume of cytoplasm, is polyploidy and is usually mononuclear but is also occasionally multi-nucleate. This cell type is important in establishing maternal physiology and remodeling of the vasculature of the placenta. - GOC:tfm - MP:0001714 - MP:19876834 - @@ -32629,20 +12670,7 @@ radial glial cells acting as neural progenitors throughout life. - A thymocyte that lacks expression of CD4 and CD8. - tmeehan - 2010-12-06T03:03:38Z - double negative T cell - cell - double negative thymocyte - - - - A thymocyte that lacks expression of CD4 and CD8. - GOC:tfm - MP:0002407 - @@ -32650,19 +12678,7 @@ radial glial cells acting as neural progenitors throughout life. - A supporting cell of the organ of Corti. - tmeehan - 2010-12-06T03:09:01Z - cell - organ of Corti supporting cell - - - - A supporting cell of the organ of Corti. - GOC:tfm - MP:0004300 - @@ -32670,18 +12686,7 @@ radial glial cells acting as neural progenitors throughout life. - A specialized cell involved in auditory sensory perception. - tmeehan - 2010-12-06T03:18:43Z - cell - auditory epithelial cell - - - - A specialized cell involved in auditory sensory perception. - GOC:tfm - @@ -32689,19 +12694,7 @@ radial glial cells acting as neural progenitors throughout life. - A polarized columnar cell that covesr the lateral surface of the cochlear duct, secretes potassium ions and forms a continuous sheet in contact with the endolymph; marginal cells form extensive interdigitations with the basal and intermediate cells in the normal adult stria. - tmeehan - 2010-12-06T03:20:41Z - cell - strial marginal cell - - - - A polarized columnar cell that covesr the lateral surface of the cochlear duct, secretes potassium ions and forms a continuous sheet in contact with the endolymph; marginal cells form extensive interdigitations with the basal and intermediate cells in the normal adult stria. - GOC:tfm - MP:0004366 - @@ -32709,20 +12702,7 @@ radial glial cells acting as neural progenitors throughout life. - A polarized cell that is juxtaposed to fibrocytes in the underlying spiral ligament. This cell type secretes potassium ions derived from fibrocytes through gap junctions. - tmeehan - 2010-12-06T03:26:53Z - cell - Basal cells form a multi-layered epithelial barrier that separates the extracellular spaces of the stria vascularis and the spiral ligament[PMID:18353863] - strial basal cell - - - - A polarized cell that is juxtaposed to fibrocytes in the underlying spiral ligament. This cell type secretes potassium ions derived from fibrocytes through gap junctions. - GOC:tfm - MP:0004365 - @@ -32731,24 +12711,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell located in the heart, including both muscle and non muscle cells. - tmeehan - 2010-12-07T09:37:22Z - BTO:0001539 - CALOHA:TS-0115 - FMA:83808 - FMA:84791 - heart cell - cell - From Onard of the FMA: Cardiac muscle cell or cardiac myocyte is a striated muscle cell. Cardiocyte on the other hand is any cell in the heart which includes cells other than muscle cells (e.g. endothelial cell of endocardium). Unless there is a consensus among anatomists that cardiocytes refer only to muscle cells, we will treat them as a general class of cells in the heart. - cardiocyte - - - - - A cell located in the heart, including both muscle and non muscle cells. - GOC:tfm - + @@ -32756,21 +12719,7 @@ radial glial cells acting as neural progenitors throughout life. - A fetal and neonatal heart cell that undergoes proliferation and is not yet terminally differentiated into a binucleate or a multinucleate cardiac myocyte. - tmeehan - 2010-12-07T09:50:41Z - embryonic cardiomyocyte - neonatal cardiomyocyte - cell - fetal cardiomyocyte - - - - A fetal and neonatal heart cell that undergoes proliferation and is not yet terminally differentiated into a binucleate or a multinucleate cardiac myocyte. - GOC:tfm - MP:0008788 - @@ -32778,22 +12727,7 @@ radial glial cells acting as neural progenitors throughout life. - A T cell that is located in the intestinal epithelium and is capable of a mucosal immune response. - tmeehan - 2010-12-07T09:54:50Z - IEL - intraepithelial T cell - intraepithelial T-cell - cell - intraepithelial lymphocyte - - - - A T cell that is located in the intestinal epithelium and is capable of a mucosal immune response. - GOC:tfm - MP:0008894 - @@ -32801,20 +12735,7 @@ radial glial cells acting as neural progenitors throughout life. - A trophoblast giant cell derived from the mural trophectoderm. - tmeehan - 2010-12-07T10:07:47Z - EMAPA:16066 - cell - primary trophoblast giant cell - - - - A trophoblast giant cell derived from the mural trophectoderm. - GOC:tfm - PMCID:PMC85124 - @@ -32822,19 +12743,7 @@ radial glial cells acting as neural progenitors throughout life. - A trophoblast giant cell that is derived from ectoplacental cone and, later in gestation, the spongiotrophoblast. - tmeehan - 2010-12-07T10:07:52Z - cell - secondary trophoblast giant cell - - - - A trophoblast giant cell that is derived from ectoplacental cone and, later in gestation, the spongiotrophoblast. - GOC:tfm - PMCID:PMC85124 - @@ -32842,19 +12751,7 @@ radial glial cells acting as neural progenitors throughout life. - A trophoblast cell that arises in the junctional zone (basal plate) of the placenta. - tmeehan - 2010-12-07T12:56:56Z - cell - spongiotrophoblast cell - - - - A trophoblast cell that arises in the junctional zone (basal plate) of the placenta. - GOC:tfm - MP:0008959 - @@ -32862,19 +12759,7 @@ radial glial cells acting as neural progenitors throughout life. - A P/D1 enteroendocrine cell that is Grimelius positive and stores bombesin-like polypeptide. - tmeehan - 2010-12-07T03:42:06Z - cell - P enteroendocrine cell - - - - A P/D1 enteroendocrine cell that is Grimelius positive and stores bombesin-like polypeptide. - FMA:63418 - GOC:tfm - @@ -32882,20 +12767,7 @@ radial glial cells acting as neural progenitors throughout life. - A P/D1 enteroendocrine cell that is argyrophilic and stores vasoactive intestinal polypeptide. - tmeehan - 2010-12-07T03:42:09Z - FMA:63207 - cell - type D1 enteroendocrine cell - - - - A P/D1 enteroendocrine cell that is argyrophilic and stores vasoactive intestinal polypeptide. - FMA:63207 - GOC:tfm - @@ -32905,21 +12777,7 @@ radial glial cells acting as neural progenitors throughout life. - An enteroendocrine cell of the small intestine that secretes motilin. - tmeehan - 2010-12-07T03:55:49Z - Mo enteroendocrine cell - FMA:63420 - cell - type M enteroendocrine cell - - - - An enteroendocrine cell of the small intestine that secretes motilin. - GOC:tfm - PMID:15153415 - @@ -32928,20 +12786,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell of the adventitial layer of ductal structures such as the uterer, defent duct, biliary duct, etc - tmeehan - 2010-12-07T04:03:56Z - BTO:0002441 - FMA:84639 - cell - adventitial cell - - - - A cell of the adventitial layer of ductal structures such as the uterer, defent duct, biliary duct, etc - GOC:tfm - @@ -32949,19 +12794,7 @@ radial glial cells acting as neural progenitors throughout life. - A smooth muscle cell of the intestine. - tmeehan - 2011-01-17T03:39:38Z - intestinal smooth muscle cell - cell - enteric smooth muscle cell - - - - A smooth muscle cell of the intestine. - GOC:tfm - @@ -32969,20 +12802,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD11b-positive dendritic cell that is CD11b-high, CD45-positive, MHC-II-positive and CD103-negative. - tmeehan - 2011-01-21T01:27:41Z - DC.103-11b+.Lv - cell - liver CD103-negative dendritic cell - - - - A CD11b-positive dendritic cell that is CD11b-high, CD45-positive, MHC-II-positive and CD103-negative. - GOC:tfm - http:http://www.immgen.org/index_content.html - @@ -32991,20 +12811,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD11b-positive dendritic cell that is CD11b-low, CD45-positive, MHC-II-high and CD103-positive that is located in the liver. - tmeehan - 2011-01-21T01:27:45Z - DC.103+11b-.Lv - cell - liver CD103-positive dendritic cell - - - - A CD11b-positive dendritic cell that is CD11b-low, CD45-positive, MHC-II-high and CD103-positive that is located in the liver. - GOC:tfm - http:http://www.immgen.org/index_content.html - @@ -33012,19 +12819,7 @@ radial glial cells acting as neural progenitors throughout life. - A dermal dendritic cell isolated from skin draining lymph nodes that is langerin-positive, MHC-II-positive, and CD4-negative and CD8a-negative. - tmeehan - 2011-01-21T01:57:00Z - cell - langerin-positive lymph node dendritic cell - - - - A dermal dendritic cell isolated from skin draining lymph nodes that is langerin-positive, MHC-II-positive, and CD4-negative and CD8a-negative. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -33032,19 +12827,7 @@ radial glial cells acting as neural progenitors throughout life. - A dermal dendritic cell isolated from skin draining lymph nodes that is langerin-negative, MHC-II-positive, and CD4-negative and CD8a-negative. - tmeehan - 2011-01-21T02:13:58Z - cell - langerin-negative, CD103-negative lymph node dendritic cell - - - - A dermal dendritic cell isolated from skin draining lymph nodes that is langerin-negative, MHC-II-positive, and CD4-negative and CD8a-negative. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -33054,19 +12837,7 @@ radial glial cells acting as neural progenitors throughout life. - A langerin-positive lymph node dendritic cell that is CD103-positive and CD11b-low. - tmeehan - 2011-01-21T02:07:54Z - cell - CD103-positive, langerin-positive lymph node dendritic cell - - - - A langerin-positive lymph node dendritic cell that is CD103-positive and CD11b-low. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -33075,19 +12846,7 @@ radial glial cells acting as neural progenitors throughout life. - A langerin-positive lymph node dendritic cell that is CD103-negative and CD11b-high. - tmeehan - 2011-01-21T02:11:14Z - cell - CD103-negative, langerin-positive lymph node dendritic cell - - - - A langerin-positive lymph node dendritic cell that is CD103-negative and CD11b-high. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -33096,19 +12855,7 @@ radial glial cells acting as neural progenitors throughout life. - A langerin-negative lymph node dendritic cell that is CD103-negative and CD11b-low. - tmeehan - 2011-01-21T02:22:15Z - cell - CD11b-low, CD103-negative, langerin-negative lymph node dendritic cell - - - - A langerin-negative lymph node dendritic cell that is CD103-negative and CD11b-low. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -33117,19 +12864,7 @@ radial glial cells acting as neural progenitors throughout life. - A langerin-negative lymph node dendritic cell that is CD103-negative and CD11b-high. - tmeehan - 2011-01-21T02:16:21Z - cell - CD11b-high, CD103-negative, langerin-negative lymph node dendritic cell - - - - A langerin-negative lymph node dendritic cell that is CD103-negative and CD11b-high. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -33137,20 +12872,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD8alpha alpha positive gamma-delta intraepithelial T cell that expresses a TCR encoded in part by the Vgamma5 gene segment. - tmeehan - 2011-01-24T10:22:18Z - tgd.vg5+.IEL - cell - Vgamma5-positive CD8alpha alpha positive gamma-delta intraepithelial T cell - - - - A CD8alpha alpha positive gamma-delta intraepithelial T cell that expresses a TCR encoded in part by the Vgamma5 gene segment. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -33158,20 +12880,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD8alpha alpha positive gamma-delta intraepithelial T cell that does not express a TCR partially encoded by the Vgamma5 gene segment. - tmeehan - 2011-01-24T10:25:44Z - tgd.vg5-.IEL - cell - Vgamma5-negative CD8alpha alpha positive gamma-delta intraepithelial T cell - - - - A CD8alpha alpha positive gamma-delta intraepithelial T cell that does not express a TCR partially encoded by the Vgamma5 gene segment. - GOC:tfm - http://www.immgen.org/index_content.html - @@ -33180,22 +12889,7 @@ radial glial cells acting as neural progenitors throughout life. - An interrenal chromaffin cell found in teleosts that contain heterogeneous vesicles with electron-dense granules located asymmetrically within the vesicular membrane. - tmeehan - 2011-02-08T10:11:55Z - interrenal noradrenaline type cell - type n interrenal cell - cell - interrenal norepinephrine type cell - - - - An interrenal chromaffin cell found in teleosts that contain heterogeneous vesicles with electron-dense granules located asymmetrically within the vesicular membrane. - GOC:MH - GOC:tfm - PMID:12668625 - @@ -33203,20 +12897,7 @@ radial glial cells acting as neural progenitors throughout life. - A chromaffin cell interspersed among the interrenal epithelial layer of the anterior kidney of teloest fish. - tmeehan - 2011-02-08T10:21:35Z - cell - interrenal chromaffin cell - - - - A chromaffin cell interspersed among the interrenal epithelial layer of the anterior kidney of teloest fish. - GOC:MH - GOC:tfm - PMID:12668625 - @@ -33225,22 +12906,7 @@ radial glial cells acting as neural progenitors throughout life. - An interrenal chromaffin cell found in teleosts that contain small, homogeneous electron-lucent granules that are separated from the vesicular membrane by a visible halo. - tmeehan - 2011-02-08T10:27:05Z - type a interrenal cell - cell - interrenal adrenaline secreting cell - interrenal epinephrin secreting cell - - - - An interrenal chromaffin cell found in teleosts that contain small, homogeneous electron-lucent granules that are separated from the vesicular membrane by a visible halo. - GOC:MH - GOC:tfm - PMID:12668625 - @@ -33249,20 +12915,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell of the kidney. - tmeehan - 2011-02-08T10:46:34Z - KUPO:0001019 - cell - kidney epithelial cell - - - - An epithelial cell of the kidney. - GOC:tfm - KUPO:SJ - @@ -33270,20 +12923,7 @@ radial glial cells acting as neural progenitors throughout life. - An interrenal epithelial kidney cell is an epithelial cell found in the anterior kidney of teleosts fish. This cell type is arranged in layers around the posterior cardinal vein and contains many mitochondria with tubulovesicular cristae. Interrenal chromaffin cells are interspersed among the tissue layer created by this cell type. - tmeehan - 2011-02-08T11:03:32Z - cell - interrenal epithelial cell - - - - An interrenal epithelial kidney cell is an epithelial cell found in the anterior kidney of teleosts fish. This cell type is arranged in layers around the posterior cardinal vein and contains many mitochondria with tubulovesicular cristae. Interrenal chromaffin cells are interspersed among the tissue layer created by this cell type. - GOC:mh - GOC:tfm - PMID:12668625 - @@ -33291,21 +12931,7 @@ radial glial cells acting as neural progenitors throughout life. - An insect excretory cell that regulates haemolymph composition by filtration and filtrate endocytosis. - tmeehan - 2011-02-08T01:34:56Z - BTO:0004597 - FMA:83807 - cell - nephrocyte - - - - An insect excretory cell that regulates haemolymph composition by filtration and filtrate endocytosis. - GOC:tfm - PMID:19783135 - @@ -33313,19 +12939,7 @@ radial glial cells acting as neural progenitors throughout life. - A fat cell that is part of subcutaneous adipose tissue. - tmeehan - 2011-02-21T02:51:22Z - subcutaneous adipocyte - cell - subcutaneous fat cell - - - - A fat cell that is part of subcutaneous adipose tissue. - GOC:tfm - @@ -33333,18 +12947,7 @@ radial glial cells acting as neural progenitors throughout life. - A renal filtration cell is a specialized cell of the renal system that filter fluids by charge, size or both. - tmeehan - 2011-02-08T01:37:59Z - cell - renal filtration cell - - - - A renal filtration cell is a specialized cell of the renal system that filter fluids by charge, size or both. - GOC:tfm - @@ -33352,18 +12955,7 @@ radial glial cells acting as neural progenitors throughout life. - A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains "feet" that interdigitate with the "feet" of other glomerular epithelial cells in the mesonephros - tmeehan - 2011-02-08T01:58:30Z - cell - mesonephric glomerular visceral epithelial cell - - - - A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains "feet" that interdigitate with the "feet" of other glomerular epithelial cells in the mesonephros - GOC:tfm - @@ -33371,19 +12963,7 @@ radial glial cells acting as neural progenitors throughout life. - A disseminated nephrocyte is a nephrocyte that filters hemolymph and is found at scattered locations in the fat body or other tissues. - tmeehan - 2011-02-08T02:07:33Z - cell - disseminated nephrocyte - - - - A disseminated nephrocyte is a nephrocyte that filters hemolymph and is found at scattered locations in the fat body or other tissues. - GOC:tfm - PMID:19783135 - @@ -33391,18 +12971,7 @@ radial glial cells acting as neural progenitors throughout life. - A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains "feet" that interdigitate with the "feet" of other glomerular epithelial cells in the metanephros. - tmeehan - 2011-02-08T02:02:13Z - cell - metanephric glomerular visceral epithelial cell - - - - A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains "feet" that interdigitate with the "feet" of other glomerular epithelial cells in the metanephros. - GOC:tfm - @@ -33410,20 +12979,7 @@ radial glial cells acting as neural progenitors throughout life. - A dermal dendritic cell that is CD1a-negative and CD14-positive. - CD14+ dermal DC - cell - They are also CD11c-positive, CD40-positive, CD85j-positive (ILT-2), CD163-positive, CD205-positive (DEC205), CD207-negative (langerin), CD209-positive (DC-SIGN), CD274-positive (PD-L1), CD324-negative (E-cadherin), Factor XIIIa-positive, LOX-I-positive, CLEC6-positive, Dectin-1-positive, and DCIR-positive. Upon stimulation, these cells are capable of producing IL1-beta, IL6, IL8, IL10, IL12p40, IL19, IL20, IL24, TGF-beta, TNF-alpha, GM-CSF, and MCP1. They reside in the dermis. - CD14-positive dermal dendritic cell - - - - A dermal dendritic cell that is CD1a-negative and CD14-positive. - GOC:dsd - PMID:19236899 - PMID:20309010 - @@ -33432,16 +12988,7 @@ radial glial cells acting as neural progenitors throughout life. - An immature CD14-positive dermal dendritic cell is CD80-low, CD86-low, and MHCII-low. - cell - immature CD14-positive dermal dendritic cell - - - - An immature CD14-positive dermal dendritic cell is CD80-low, CD86-low, and MHCII-low. - GOC:dsd - @@ -33450,16 +12997,7 @@ radial glial cells acting as neural progenitors throughout life. - A mature CD14-positive dermal dendritic cell is CD80-high, CD86-high, MHCII-high and is CD83-positive. - cell - mature CD14-positive dermal dendritic cell - - - - A mature CD14-positive dermal dendritic cell is CD80-high, CD86-high, MHCII-high and is CD83-positive. - GOC:dsd - @@ -33467,19 +13005,7 @@ radial glial cells acting as neural progenitors throughout life. - A dermal dendritic cell that is CD1a-positive and CD14-negative. - CD1a+ dermal DC - cell - Reside in the dermis. They are also CD11c-positive, CD40-positive, CD207-negative (langerin), CD209-negative (DC-SIGN), and CD324-negative (E-cadherin). When activated, they are capable of producing CXCL8 (IL-8) and IL-15. Possibly a precursor of Langerhans cells or equivalent of langerin-positive dermal DCs in the mouse. - CD1a-positive dermal dendritic cell - - - - A dermal dendritic cell that is CD1a-positive and CD14-negative. - GOC:dsd - PMID:20309010 - @@ -33488,16 +13014,7 @@ radial glial cells acting as neural progenitors throughout life. - An immature CD1a-positive dermal dendritic cell is CD80-low, CD86-low, and MHCII-low. - cell - immature CD1a-positive dermal dendritic cell - - - - An immature CD1a-positive dermal dendritic cell is CD80-low, CD86-low, and MHCII-low. - GOC:dsd - @@ -33506,16 +13023,7 @@ radial glial cells acting as neural progenitors throughout life. - A mature CD1a-positive dermal dendritic cell is CD80-high, CD83-positive, CD86-high, and MHCII-high. - cell - mature CD1a-positive dermal dendritic cell - - - - A mature CD1a-positive dermal dendritic cell is CD80-high, CD83-positive, CD86-high, and MHCII-high. - GOC:dsd - @@ -33523,20 +13031,7 @@ radial glial cells acting as neural progenitors throughout life. - A myeloid dendritic cell found in the blood that is CD16-positive. - CD16+ mDC - CD16-mDC - cell - Normally represent 65-75% of peripheral blood mDCs (human). They are also CD281-positive (TLR1), CD282-positive (TLR2), CD284-positive (TLR4), CD285-positive (TLR5), CD286-positive (TLR6), CD288-positive (TLR8), CD289-positive (TLR9), and CD290-positive (TLR10) by RT-PCR [PMID:17332250]. Upon TLR stimulation, these cells are potent producers of TNF-alpha, while producing little CXCL8 (IL8). - CD16-positive myeloid dendritic cell - - - - A myeloid dendritic cell found in the blood that is CD16-positive. - GOC:dsd - PMID:17332250 - @@ -33545,16 +13040,7 @@ radial glial cells acting as neural progenitors throughout life. - An immature CD16-positive myeloid dendritic cell is CD80-low, CD86-low, and MHCII-low. - cell - immature CD16-positive myeloid dendritic cell - - - - An immature CD16-positive myeloid dendritic cell is CD80-low, CD86-low, and MHCII-low. - GOC:dsd - @@ -33563,16 +13049,7 @@ radial glial cells acting as neural progenitors throughout life. - A mature CD16-positive myeloid dendritic cell is CD80-high, CD83-positive, CD86-high, and MHCII-high. - cell - mature CD16-positive myeloid dendritic cell - - - - A mature CD16-positive myeloid dendritic cell is CD80-high, CD83-positive, CD86-high, and MHCII-high. - GOC:dsd - @@ -33581,95 +13058,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell of the cervix. - tmeehan - 2011-02-24T08:20:08Z - cervical canal epithelial cell - cervical canal of uterus epithelial cell - cervix epithelial cell - cervix of uterus epithelial cell - epithelial cell of cervical canal - epithelial cell of cervical canal of uterus - epithelial cell of cervix of uterus - epithelial cell of neck of uterus - epithelial cell of uterine cervix - neck of uterus epithelial cell - uterine cervix epithelial cell - cell - epithelial cell of cervix - - - - - An epithelial cell of the cervix. - GOC:tfm - - - - - cervical canal epithelial cell - GOC:tfm - - - - - cervical canal of uterus epithelial cell - GOC:tfm - - - - - cervix epithelial cell - GOC:tfm - - - - - cervix of uterus epithelial cell - GOC:tfm - - - - - epithelial cell of cervical canal - GOC:tfm - - - - - epithelial cell of cervical canal of uterus - GOC:tfm - - - - - epithelial cell of cervix of uterus - GOC:tfm - - - - - epithelial cell of neck of uterus - GOC:tfm - - - - - epithelial cell of uterine cervix - GOC:tfm - - - - - neck of uterus epithelial cell - GOC:tfm - - - - - uterine cervix epithelial cell - GOC:tfm - + @@ -33678,19 +13067,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell that is part of the amnion. - tmeehan - 2011-02-28T12:38:01Z - amniotic epithelial cell - cell - epithelial cell of amnion - - - - An epithelial cell that is part of the amnion. - GOC:tfm - @@ -33698,21 +13075,7 @@ radial glial cells acting as neural progenitors throughout life. - A mesenchymal stem cell of the amnion membrane. - tmeehan - 2011-02-28T12:44:24Z - amniotic membrane stem cell - cell - amnion mesenchymal stem cell - - - - A mesenchymal stem cell of the amnion membrane. - GOC:tfm - PMID:20446274 - PMID:21339039 - @@ -33720,18 +13083,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell of the intrahepatic portion of the bile duct. - tmeehan - 2011-02-28T01:20:20Z - cell - intrahepatic bile duct epithelial cell - - - - An epithelial cell of the intrahepatic portion of the bile duct. - GOC:tfm - @@ -33739,19 +13091,7 @@ radial glial cells acting as neural progenitors throughout life. - A smooth muscle cell of the aorta. - tmeehan - 2011-02-28T01:42:12Z - BTO:0004577 - cell - aortic smooth muscle cell - - - - A smooth muscle cell of the aorta. - GOC:tfm - @@ -33760,18 +13100,7 @@ radial glial cells acting as neural progenitors throughout life. - A mesenchymal stem cell that is part of the bone marrow. - tmeehan - 2011-02-28T01:47:47Z - cell - mesenchymal stem cell of the bone marrow - - - - A mesenchymal stem cell that is part of the bone marrow. - GOC:tfm - @@ -33779,18 +13108,7 @@ radial glial cells acting as neural progenitors throughout life. - A mesenchymal stem cell of the chorionic membrane. - tmeehan - 2011-02-28T03:04:35Z - cell - chorionic membrane mesenchymal stem cell - - - - A mesenchymal stem cell of the chorionic membrane. - GOC:tfm - @@ -33798,23 +13116,7 @@ radial glial cells acting as neural progenitors throughout life. - An endothelial cell that is part of the vein. - tmeehan - 2011-02-28T03:48:11Z - CL:1000393 - FMA:62104 - KUPO:0001099 - endothelial cell of vein - venous endothelial cell - cell - vein endothelial cell - - - - - An endothelial cell that is part of the vein. - GOC:tfm - + @@ -33822,20 +13124,7 @@ radial glial cells acting as neural progenitors throughout life. - An arterial endothelial cell that is part of the aorta endothelium. - tmeehan - 2011-02-28T03:54:42Z - BTO:0003245 - CALOHA:TS-0047 - cell - aortic endothelial cell - - - - An arterial endothelial cell that is part of the aorta endothelium. - GOC:tfm - @@ -33843,18 +13132,7 @@ radial glial cells acting as neural progenitors throughout life. - An endothelial cell that is part of the thoracic endothelium. - tmeehan - 2011-02-28T03:59:09Z - cell - thoracic aorta endothelial cell - - - - An endothelial cell that is part of the thoracic endothelium. - GOC:tfm - @@ -33863,19 +13141,7 @@ radial glial cells acting as neural progenitors throughout life. - An endothelial progenitor cell that participates in angiogenesis during development. - tmeehan - 2011-02-28T04:20:39Z - cell - See CL:0002619. - embryonic blood vessel endothelial progenitor cell - - - - An endothelial progenitor cell that participates in angiogenesis during development. - GOC:tfm - @@ -33883,18 +13149,7 @@ radial glial cells acting as neural progenitors throughout life. - A fibroblast of the aortic adventitia. - tmeehan - 2011-02-28T04:43:41Z - cell - fibroblast of the aortic adventitia - - - - A fibroblast of the aortic adventitia. - GOC:tfm - @@ -33903,19 +13158,7 @@ radial glial cells acting as neural progenitors throughout life. - A fibroblast that is part of the heart. - tmeehan - 2011-02-28T04:57:44Z - cardiac fibroblast - cell - fibroblast of cardiac tissue - - - - A fibroblast that is part of the heart. - GOC:tfm - @@ -33924,18 +13167,7 @@ radial glial cells acting as neural progenitors throughout life. - A fibroblast that is part of the choroid plexus. - tmeehan - 2011-02-28T05:01:39Z - cell - fibroblast of choroid plexus - - - - A fibroblast that is part of the choroid plexus. - GOC:tfm - @@ -33943,18 +13175,7 @@ radial glial cells acting as neural progenitors throughout life. - A fibroblast that is part of the conjuctiva of the eye. - tmeehan - 2011-02-28T05:03:44Z - cell - fibroblast of the conjunctiva - - - - A fibroblast that is part of the conjuctiva of the eye. - GOC:tfm - @@ -33962,10 +13183,6 @@ radial glial cells acting as neural progenitors throughout life. - tmeehan - 2011-02-28T05:05:33Z - cell - fibroblast of dermis @@ -33974,10 +13191,6 @@ radial glial cells acting as neural progenitors throughout life. - tmeehan - 2011-02-28T05:09:12Z - cell - fibroblast of gingiva @@ -33986,20 +13199,7 @@ radial glial cells acting as neural progenitors throughout life. - A fibroblast that is part of lung. - tmeehan - 2011-02-28T05:11:03Z - BTO:0000764 - CALOHA:TS-0575 - cell - fibroblast of lung - - - - A fibroblast that is part of lung. - GOC:tfm - @@ -34007,18 +13207,7 @@ radial glial cells acting as neural progenitors throughout life. - A fibroblast of the lymphatic system. - tmeehan - 2011-02-28T05:16:18Z - cell - fibroblast of lymphatic vessel - - - - A fibroblast of the lymphatic system. - GOC:tfm - @@ -34026,18 +13215,7 @@ radial glial cells acting as neural progenitors throughout life. - A fibroblast that is part of the mammary gland. - tmeehan - 2011-02-28T05:18:38Z - cell - fibroblast of mammary gland - - - - A fibroblast that is part of the mammary gland. - GOC:tfm - @@ -34045,18 +13223,7 @@ radial glial cells acting as neural progenitors throughout life. - A fibroblast of the periodontium. - tmeehan - 2011-02-28T05:19:48Z - cell - fibroblast of periodontium - - - - A fibroblast of the periodontium. - GOC:tfm - @@ -34064,18 +13231,7 @@ radial glial cells acting as neural progenitors throughout life. - A fibroblast of pulmonary artery. - tmeehan - 2011-02-28T05:22:27Z - cell - fibroblast of pulmonary artery - - - - A fibroblast of pulmonary artery. - GOC:tfm - @@ -34083,18 +13239,7 @@ radial glial cells acting as neural progenitors throughout life. - A fibroblast that is part of villous mesenchyme. - tmeehan - 2011-02-28T05:24:28Z - cell - fibroblast of villous mesenchyme - - - - A fibroblast that is part of villous mesenchyme. - GOC:tfm - @@ -34102,18 +13247,7 @@ radial glial cells acting as neural progenitors throughout life. - An animal cell that is part of a hair follicle. - tmeehan - 2011-03-01T04:11:01Z - cell - hair follicle cell - - - - An animal cell that is part of a hair follicle. - GOC:tfm - @@ -34122,18 +13256,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell that resides in the inner root sheath of the hair follicle. - tmeehan - 2011-03-01T04:27:51Z - cell - inner root sheath cell - - - - An epithelial cell that resides in the inner root sheath of the hair follicle. - GOC:tfm - @@ -34142,18 +13265,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell that is part of the outer root sheath. - tmeehan - 2011-03-01T04:29:47Z - cell - outer root sheath cell - - - - An epithelial cell that is part of the outer root sheath. - GOC:tfm - @@ -34162,19 +13274,7 @@ radial glial cells acting as neural progenitors throughout life. - An epidermal cell that is part of the germinal matrix. - tmeehan - 2011-03-01T04:31:06Z - trichocyte - cell - hair germinal matrix cell - - - - An epidermal cell that is part of the germinal matrix. - GOC:tfm - @@ -34182,18 +13282,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell of the intestine. - tmeehan - 2011-03-01T05:18:31Z - cell - intestinal epithelial cell - - - - An epithelial cell of the intestine. - GOC:tfm - @@ -34201,18 +13290,7 @@ radial glial cells acting as neural progenitors throughout life. - A connective tissue cell of the nucleus pulposus cell of intervertebral disc. - tmeehan - 2011-03-02T02:12:23Z - cell - nucleus pulposus cell of intervertebral disc - - - - A connective tissue cell of the nucleus pulposus cell of intervertebral disc. - GOC:tfm - @@ -34221,18 +13299,7 @@ radial glial cells acting as neural progenitors throughout life. - A pigment cell located in the epithelium of the iris. - tmeehan - 2011-03-01T05:28:52Z - cell - iris pigment epithelial cell - - - - A pigment cell located in the epithelium of the iris. - GOC:tfm - @@ -34240,18 +13307,7 @@ radial glial cells acting as neural progenitors throughout life. - A melanocyte that appears darker due to content or amount of melanin granules. - tmeehan - 2011-03-01T05:57:11Z - cell - dark melanocyte - - - - A melanocyte that appears darker due to content or amount of melanin granules. - GOC:tfm - @@ -34259,18 +13315,7 @@ radial glial cells acting as neural progenitors throughout life. - A melanocyte that appears lighter in color. - tmeehan - 2011-03-01T05:58:23Z - cell - light melanocyte - - - - A melanocyte that appears lighter in color. - GOC:tfm - @@ -34278,18 +13323,7 @@ radial glial cells acting as neural progenitors throughout life. - A mesenchymal stem cell that is part of Wharton's jelly. - tmeehan - 2011-03-01T09:51:18Z - cell - mesenchymal stem cell of Wharton's jelly - - - - A mesenchymal stem cell that is part of Wharton's jelly. - GOC:tfm - @@ -34298,18 +13332,7 @@ radial glial cells acting as neural progenitors throughout life. - A mesenchymal stem cell of the umbilical cord. - tmeehan - 2011-03-01T09:55:12Z - cell - mesenchymal stem cell of umbilical cord - - - - A mesenchymal stem cell of the umbilical cord. - GOC:tfm - @@ -34317,18 +13340,7 @@ radial glial cells acting as neural progenitors throughout life. - A mesenchymal stem cell of adipose tissue. - tmeehan - 2011-03-01T09:57:17Z - cell - mesenchymal stem cell of adipose - - - - A mesenchymal stem cell of adipose tissue. - GOC:tfm - @@ -34337,18 +13349,7 @@ radial glial cells acting as neural progenitors throughout life. - A mesenchymal stem cell of liver. - tmeehan - 2011-03-01T09:58:51Z - cell - hepatic mesenchymal stem cell - - - - A mesenchymal stem cell of liver. - GOC:tfm - @@ -34357,18 +13358,7 @@ radial glial cells acting as neural progenitors throughout life. - A mesenchymal stem cell of the vertebrae. - tmeehan - 2011-03-01T10:40:27Z - cell - vertebral mesenchymal stem cell - - - - A mesenchymal stem cell of the vertebrae. - GOC:tfm - @@ -34376,20 +13366,7 @@ radial glial cells acting as neural progenitors throughout life. - A glial cell that ensheathes axons of neuron in the peripheral nervous system and are necessary for their maintainance and function. - tmeehan - 2011-03-02T01:19:27Z - BTO:0001220 - CALOHA:TS-0898 - cell - Schwann cell - - - - A glial cell that ensheathes axons of neuron in the peripheral nervous system and are necessary for their maintainance and function. - GOC:tfm - @@ -34397,18 +13374,7 @@ radial glial cells acting as neural progenitors throughout life. - A stromal cell of the pancreas. - tmeehan - 2011-03-02T02:40:41Z - cell - stromal cell of pancreas - - - - A stromal cell of the pancreas. - GOC:tfm - @@ -34417,18 +13383,7 @@ radial glial cells acting as neural progenitors throughout life. - A pericyte of the central nervous system. - tmeehan - 2011-03-02T02:54:18Z - cell - central nervous system pericyte - - - - A pericyte of the central nervous system. - GOC:tfm - @@ -34438,19 +13393,7 @@ radial glial cells acting as neural progenitors throughout life. - A myofibroblast that lies in the connective tissue of the spinal cord that has a distinctly lamellar arrangement. - tmeehan - 2011-03-02T03:03:58Z - cell - perineural cell - - - - A myofibroblast that lies in the connective tissue of the spinal cord that has a distinctly lamellar arrangement. - GO:tfm - http://en.wikipedia.org/wiki/Perineurium - @@ -34459,18 +13402,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell of the placenta. - tmeehan - 2011-03-02T03:21:30Z - cell - placental epithelial cell - - - - An epithelial cell of the placenta. - GOC:tfm - @@ -34478,18 +13410,7 @@ radial glial cells acting as neural progenitors throughout life. - A preadipocyte found in mesenteric tissue. - tmeehan - 2011-03-03T04:19:40Z - cell - mesenteric preadipocyte - - - - A preadipocyte found in mesenteric tissue. - GOC:tfm - @@ -34497,10 +13418,6 @@ radial glial cells acting as neural progenitors throughout life. - tmeehan - 2011-03-03T04:19:42Z - cell - omentum preadipocyte @@ -34509,18 +13426,7 @@ radial glial cells acting as neural progenitors throughout life. - A preadipocyte that is part of the breast. - tmeehan - 2011-03-03T04:19:46Z - cell - preadipocyte of the breast - - - - A preadipocyte that is part of the breast. - GOC:tfm - @@ -34528,10 +13434,6 @@ radial glial cells acting as neural progenitors throughout life. - tmeehan - 2011-03-03T04:20:04Z - cell - perirenal preadipocyte @@ -34540,18 +13442,7 @@ radial glial cells acting as neural progenitors throughout life. - A preadipocyte that is part of visceral tissue. - tmeehan - 2011-03-03T04:32:56Z - cell - visceral preadipocyte - - - - A preadipocyte that is part of visceral tissue. - GOC:tfm - @@ -34559,18 +13450,7 @@ radial glial cells acting as neural progenitors throughout life. - A preadipocyte that is part of subcutaneous tissue. - tmeehan - 2011-03-03T04:33:01Z - cell - subcutaneous preadipocyte - - - - A preadipocyte that is part of subcutaneous tissue. - GOC:tfm - @@ -34579,17 +13459,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell of the kidney cortex. - KUPO:0001016 - cell - renal cortical epithelial cell - - - - An epithelial cell of the kidney cortex. - GOC:tfm - @@ -34598,18 +13468,7 @@ radial glial cells acting as neural progenitors throughout life. - A blood vessel endothelial cell that is part of the retina. - tmeehan - 2011-03-06T03:28:27Z - cell - retinal blood vessel endothelial cell - - - - A blood vessel endothelial cell that is part of the retina. - GOC:tfm - @@ -34619,20 +13478,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell of the retinal pigmented epithelium. - tmeehan - 2011-03-06T03:37:09Z - BTO:0004910 - FMA:75802 - cell - retinal pigment epithelial cell - - - - An epithelial cell of the retinal pigmented epithelium. - GOC:tfm - @@ -34640,18 +13486,7 @@ radial glial cells acting as neural progenitors throughout life. - A smooth muscle cell of the umbilical vein. - tmeehan - 2011-03-06T05:00:51Z - cell - smooth muscle cell of the umbilical vein - - - - A smooth muscle cell of the umbilical vein. - GOC:tfm - @@ -34659,18 +13494,7 @@ radial glial cells acting as neural progenitors throughout life. - A smooth muscle cell of the bachiocephalic vasculature. - tmeehan - 2011-03-06T05:00:58Z - cell - smooth muscle cell of the brachiocephalic vasculature - - - - A smooth muscle cell of the bachiocephalic vasculature. - GOC:tfm - @@ -34679,18 +13503,7 @@ radial glial cells acting as neural progenitors throughout life. - A vascular associated smooth muscle cell of the brain vasculature. - tmeehan - 2011-03-06T05:01:20Z - cell - smooth muscle cell of the brain vasculature - - - - A vascular associated smooth muscle cell of the brain vasculature. - GOC:tfm - @@ -34698,19 +13511,7 @@ radial glial cells acting as neural progenitors throughout life. - A smooth muscle of the pulmonary artery. - tmeehan - 2011-03-06T05:01:28Z - BTO:0003336 - cell - smooth muscle cell of the pulmonary artery - - - - A smooth muscle of the pulmonary artery. - GOC:tfm - @@ -34719,18 +13520,7 @@ radial glial cells acting as neural progenitors throughout life. - A smooth muscle cell of the coronary artery. - tmeehan - 2011-03-06T05:01:34Z - cell - smooth muscle cell of the coronary artery - - - - A smooth muscle cell of the coronary artery. - GOC:tfm - @@ -34738,18 +13528,7 @@ radial glial cells acting as neural progenitors throughout life. - A smooth muscle of the internal thoracic artery. - tmeehan - 2011-03-06T05:01:41Z - cell - smooth muscle cell of the internal thoracic artery - - - - A smooth muscle of the internal thoracic artery. - GOC:tfm - @@ -34757,18 +13536,7 @@ radial glial cells acting as neural progenitors throughout life. - A smooth muscle cell of the umbilical artery. - tmeehan - 2011-03-06T05:01:48Z - cell - smooth muscle cell of the umbilical artery - - - - A smooth muscle cell of the umbilical artery. - GOC:tfm - @@ -34776,18 +13544,7 @@ radial glial cells acting as neural progenitors throughout life. - A smooth muscle cell of the subclavian artery. - tmeehan - 2011-03-06T05:01:52Z - cell - smooth muscle cell of the subclavian artery - - - - A smooth muscle cell of the subclavian artery. - GOC:tfm - @@ -34795,18 +13552,7 @@ radial glial cells acting as neural progenitors throughout life. - Smooth muscle cell of the carotid artery. - tmeehan - 2011-03-06T05:01:56Z - cell - smooth muscle cell of the carotid artery - - - - Smooth muscle cell of the carotid artery. - GOC:tfm - @@ -34815,19 +13561,7 @@ radial glial cells acting as neural progenitors throughout life. - A smooth muscle cell of the bladder. - tmeehan - 2011-03-06T05:43:24Z - KUPO:0001122 - cell - smooth muscle cell of bladder - - - - A smooth muscle cell of the bladder. - GC:tfm - @@ -34835,11 +13569,6 @@ radial glial cells acting as neural progenitors throughout life. - tmeehan - 2011-03-06T05:46:39Z - BTO:0004402 - cell - bronchial smooth muscle cell @@ -34848,18 +13577,7 @@ radial glial cells acting as neural progenitors throughout life. - A smooth muscle cell of the esophagus. - tmeehan - 2011-03-06T05:48:17Z - cell - smooth muscle cell of the esophagus - - - - A smooth muscle cell of the esophagus. - GOC:tfm - @@ -34867,18 +13585,7 @@ radial glial cells acting as neural progenitors throughout life. - A smooth muscle cell of the trachea. - tmeehan - 2011-03-06T05:50:28Z - cell - smooth muscle cell of trachea - - - - A smooth muscle cell of the trachea. - GOC:tfm - @@ -34886,18 +13593,7 @@ radial glial cells acting as neural progenitors throughout life. - A smooth muscle cell of the uterus. - tmeehan - 2011-03-06T05:53:28Z - cell - uterine smooth muscle cell - - - - A smooth muscle cell of the uterus. - GOC:tfm - @@ -34905,11 +13601,6 @@ radial glial cells acting as neural progenitors throughout life. - tmeehan - 2011-03-06T06:50:53Z - anulus pulposus cell - cell - annulus pulposus cell @@ -34919,18 +13610,7 @@ radial glial cells acting as neural progenitors throughout life. - An astrocyte of the cerebellum. - tmeehan - 2011-03-06T06:57:27Z - cell - astrocyte of the cerebellum - - - - An astrocyte of the cerebellum. - GOC:tfm - @@ -34939,10 +13619,6 @@ radial glial cells acting as neural progenitors throughout life. - tmeehan - 2011-03-06T06:57:33Z - cell - astrocyte of the hippocampus @@ -34952,18 +13628,7 @@ radial glial cells acting as neural progenitors throughout life. - An astrocyte of the cerebral cortex. - tmeehan - 2011-03-06T06:57:36Z - cell - astrocyte of the cerebral cortex - - - - An astrocyte of the cerebral cortex. - GOC:tfm - @@ -34971,18 +13636,7 @@ radial glial cells acting as neural progenitors throughout life. - An astrocyte of the spinal cord. - tmeehan - 2011-03-06T07:11:26Z - cell - astrocyte of the spinal cord - - - - An astrocyte of the spinal cord. - GOC:tfm - @@ -34990,18 +13644,7 @@ radial glial cells acting as neural progenitors throughout life. - A neural crest cell that gives rise to cells of the enteric nervous system. - tmeehan - 2011-03-06T07:24:35Z - cell - migratory enteric neural crest cell - - - - A neural crest cell that gives rise to cells of the enteric nervous system. - GOC:tfm - @@ -35009,18 +13652,7 @@ radial glial cells acting as neural progenitors throughout life. - A neuron of the hippocampus. - tmeehan - 2011-03-06T07:31:49Z - cell - hippocampal neuron - - - - A neuron of the hippocampus. - GOC:tfm - @@ -35029,21 +13661,7 @@ radial glial cells acting as neural progenitors throughout life. - A CNS neuron of the cerebral cortex. - tmeehan - 2011-03-06T07:37:08Z - BTO:0004102 - FMA:84104 - cortical neuron - cell - neuron of cerebral cortex - - - - A CNS neuron of the cerebral cortex. - GOC:tfm - @@ -35051,18 +13669,7 @@ radial glial cells acting as neural progenitors throughout life. - A neuron of the raphe nuclei. - tmeehan - 2011-03-06T07:42:06Z - cell - raphe nuclei neuron - - - - A neuron of the raphe nuclei. - GOC:tfm - @@ -35070,18 +13677,7 @@ radial glial cells acting as neural progenitors throughout life. - A CNS neuron of the dorsal spinal cord. - tmeehan - 2011-03-06T07:43:34Z - cell - neuron of the dorsal spinal cord - - - - A CNS neuron of the dorsal spinal cord. - GOC:tfm - @@ -35089,18 +13685,7 @@ radial glial cells acting as neural progenitors throughout life. - A neuron of the ventral spinal cord. - tmeehan - 2011-03-06T07:46:03Z - cell - neuron of the ventral spinal cord - - - - A neuron of the ventral spinal cord. - GOC:tfm - @@ -35108,18 +13693,7 @@ radial glial cells acting as neural progenitors throughout life. - A neuron of the striatum. - tmeehan - 2011-03-06T07:47:12Z - cell - striatum neuron - - - - A neuron of the striatum. - GOC:tfm - @@ -35127,18 +13701,7 @@ radial glial cells acting as neural progenitors throughout life. - A neuron of the substantia nigra. - tmeehan - 2011-03-06T07:48:42Z - cell - neuron of the substantia nigra - - - - A neuron of the substantia nigra. - GOC:tfm - @@ -35146,20 +13709,7 @@ radial glial cells acting as neural progenitors throughout life. - A fat cell that is part of omentum tissue. - tmeehan - 2011-03-14T10:17:00Z - omental adipocyte - omental fat cell - cell - adipocyte of omentum tissue - - - - A fat cell that is part of omentum tissue. - GOC:tfm - @@ -35167,19 +13717,7 @@ radial glial cells acting as neural progenitors throughout life. - A fat cell of perirenal fat tissue. - tmeehan - 2011-03-14T10:17:05Z - perirenal fat cell - cell - perirenal adipocyte cell - - - - A fat cell of perirenal fat tissue. - GOC:tfm - @@ -35187,22 +13725,7 @@ radial glial cells acting as neural progenitors throughout life. - A fat cell that is part of the breast. - tmeehan - 2011-03-14T10:17:07Z - CALOHA:TS-2377 - breast adipocyte - fat cell of breast - cell - Adipocytes found in the subcutaneous adipose tissue of breast. The breast consists of three main components, the skin, the subcutaneous adipose tissue and the functional glandular tissue that comprises both parenchyma and stroma.[CALOHA] - adipocyte of breast - - - - A fat cell that is part of the breast. - GOC:tfm - @@ -35210,19 +13733,7 @@ radial glial cells acting as neural progenitors throughout life. - An endothelial cell of the umbilical vein. - tmeehan - 2011-03-14T11:36:51Z - BTO:0004296 - cell - endothelial cell of umbilical vein - - - - An endothelial cell of the umbilical vein. - GOC:tfm - @@ -35230,21 +13741,7 @@ radial glial cells acting as neural progenitors throughout life. - An adult angioblastic cell released from the bone marrow, capable of blood circulation and participation in angiogenesis by differentiating into blood vessel endothelial cells. Their existence is controversial. - tmeehan - 2011-03-14T12:11:18Z - EPC - cell - adult endothelial progenitor cell - - - - An adult angioblastic cell released from the bone marrow, capable of blood circulation and participation in angiogenesis by differentiating into blood vessel endothelial cells. Their existence is controversial. - GOC:tfm - PMID:20807818 - PMID:9020076 - @@ -35252,20 +13749,7 @@ radial glial cells acting as neural progenitors throughout life. - A fibroblast of skin. - tmeehan - 2011-03-14T12:31:49Z - BTO:0001255 - CALOHA:TS-0935 - cell - skin fibroblast - - - - A fibroblast of skin. - GOC:tfm - @@ -35273,10 +13757,6 @@ radial glial cells acting as neural progenitors throughout life. - tmeehan - 2011-03-14T12:46:28Z - cell - gingival epithelial cell @@ -35285,19 +13765,7 @@ radial glial cells acting as neural progenitors throughout life. - A stromal cell of the prostate. - tmeehan - 2011-03-14T02:11:10Z - BTO:0003972 - cell - prostate stromal cell - - - - A stromal cell of the prostate. - GOC:tfm - @@ -35306,18 +13774,7 @@ radial glial cells acting as neural progenitors throughout life. - An acinar cell of salivary gland. - tmeehan - 2011-03-14T02:22:22Z - cell - acinar cell of salivary gland - - - - An acinar cell of salivary gland. - GOC:tfm - @@ -35326,18 +13783,7 @@ radial glial cells acting as neural progenitors throughout life. - A paneth cell of the appendix. - tmeehan - 2011-03-15T09:38:18Z - cell - paneth cell of the appendix - - - - A paneth cell of the appendix. - GOC:tfm - @@ -35346,18 +13792,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell of the seminiferous tubule epithelium. - tmeehan - 2011-03-15T11:59:23Z - cell - seminiferous tubule epithelial cell - - - - A cell of the seminiferous tubule epithelium. - GOC:tfm - @@ -35365,17 +13800,7 @@ radial glial cells acting as neural progenitors throughout life. - An immature astrocyte. - immature astrocytic glia - cell - immature astrocyte - - - - An immature astrocyte. - GOC:dsd - @@ -35383,21 +13808,7 @@ radial glial cells acting as neural progenitors throughout life. - A mature astrocyte that is capable of producing cytokines. - activated astrocyte - mature astrocytic glia - cell - Mature astrocytes are reportedly able to produce aspartate, ATP, BDNF, BMP-2a, BMP-3, CCL2, CCL3, CCL4, CCL5, CCL19, CCL20,CD40L, CNTF, CTGF, CXCL1, CXCL2, CXCL8, edn-1, aFGF, bFGF, G-CSF, glutamate, GM-CSF, IFN-alpha, IFN-beta, IFN-gamma, IGF-1, IL-1alpha, IL-1beta, IL-2, Il-4, IL-6, IL-10, IL-12, LIF, MIP-2, NGF, nitric oxide, NT3, taurine, TGF-beta, TNF-alpha, TNF-beta. - mature astrocyte - - - - A mature astrocyte that is capable of producing cytokines. - GOC:dsd - PMID:12898703 - PMID:8734446 - @@ -35405,34 +13816,7 @@ radial glial cells acting as neural progenitors throughout life. - An immature microglial cell with a ramified morphology. - immature microglia - quiescent microglia - resting microglia - cell - Immature microglia are reportedly CD34-positive, CD163-negative, MHCI-negative, MHCII-negative. - immature microglial cell - - - - - An immature microglial cell with a ramified morphology. - GOC:dsd - PMID:18396103 - PMID:19461673 - - - - - quiescent microglia - PMID:18396103 - - - - - resting microglia - PMID:18396103 - + @@ -35440,38 +13824,7 @@ radial glial cells acting as neural progenitors throughout life. - A mature microglial cell that has changed shape to an amoeboid morphology and is capable of cytokine production and antigen presentation. - activated microglia - mature microglia - reactive microglia - cell - Mature microglia are reportedly CCR2-positive, CD4-positive, CD9-positive, CD11a-positive, CD11b-positive, CD11c-positive, CD13-positive, CD16-positive, CDw17-positive, CD18-positive, CD21-positive, CD26-negative, CD32-positive, CD35-positive, CD36-positive, CD40-positive, CD44-positive, CD45-positive, CD53-positive, CD54-positive, CD56-negative, CD58-positive, CD63-positive, CD64-positive, CD66-positive, CD80-positive, CD86-positive, CD87-positive, CD92-positive, CD106-positive, CD107a-positive, CD147-positive, CD155-positive, CD162-positive, CD163-positive, CD171-negative, CD200R-positive, CXCR3-positive, CX3CR1-positive, fibronectin-positive, GD3-positive, GLUT1-positive, GLUT3-negative, GLUT5-positive, MHCI-positive, MHCII-positive, P2X4-positive, RFD7-negative, RGS5-negative, alpha-SMA-negative, vimentin-positive, and vwf-negative. Mature microglia are capable of producing BDNF, CCL3, CCL5, CCL7, CCL8, CCL9, CCL19, CCL20,CD40L, CSF, CXCL1, CXCL2, CXCL4, CXCL5, CXCL8, CXCL9, CXCL10, glutamate, IL-1beta, IL-1ra, IL-3, IL-6, IL-10, IL-12, LT, MMP-2, MMP-9, NGF, nitric oxide, ROS, TGF-beta, TNF-alpha. - mature microglial cell - - - - - A mature microglial cell that has changed shape to an amoeboid morphology and is capable of cytokine production and antigen presentation. - GOC:dsd - PMID:11517395 - PMID:14612429 - PMID:15246020 - PMID:16177057 - PMID:18396103 - PMID:20021364 - - - - - activated microglia - PMID:18396103 - - - - - reactive microglia - PMID:18396103 - + @@ -35479,19 +13832,7 @@ radial glial cells acting as neural progenitors throughout life. - A spore formed from bacteria in the order Actinomycetales. - tmeehan - 2011-06-16T01:01:41Z - cell - actinomycete-type spore - - - - A spore formed from bacteria in the order Actinomycetales. - GO:0034304 - GOC:tfm - @@ -35499,10 +13840,6 @@ radial glial cells acting as neural progenitors throughout life. - tmeehan - 2011-06-21T12:28:55Z - cell - epithelial cell of upper respiratory tract @@ -35511,10 +13848,6 @@ radial glial cells acting as neural progenitors throughout life. - tmeehan - 2011-06-21T12:29:31Z - cell - epithelial cell of lower respiratory tract @@ -35524,21 +13857,7 @@ radial glial cells acting as neural progenitors throughout life. - A basal cell in the respiratory tract. - tmeehan - 2011-06-21T03:11:10Z - airway basal cell - airway basal stem cell - cell - respiratory basal cell - - - - A basal cell in the respiratory tract. - GOC:tfm - PMID:20699479 - @@ -35546,18 +13865,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell of the anal column. - tmeehan - 2011-07-08T12:11:38Z - cell - epithelial cell of anal column - - - - An epithelial cell of the anal column. - GOC:tfm - @@ -35565,19 +13873,7 @@ radial glial cells acting as neural progenitors throughout life. - A nonkeratinized epithelial cell of the anal canal. - tmeehan - 2011-07-08T02:05:33Z - FMA:263146 - cell - nonkeratinized epithelial cell of anal column - - - - A nonkeratinized epithelial cell of the anal canal. - GOC:tfm - @@ -35586,19 +13882,7 @@ radial glial cells acting as neural progenitors throughout life. - A nonkeratinized cell epithleial cell of the inferior part of the anal canal. - tmeehan - 2011-07-08T02:06:53Z - FMA:263144 - cell - nonkeratinized epithelial cell of inferior part of anal canal - - - - A nonkeratinized cell epithleial cell of the inferior part of the anal canal. - GOC:tfm - @@ -35607,18 +13891,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell of the anal canal that is keratinized. This cell type is found towards the lower, rectal end of the anal canal. - tmeehan - 2011-07-08T02:08:40Z - cell - keratinized epithelial cell of the anal canal - - - - An epithelial cell of the anal canal that is keratinized. This cell type is found towards the lower, rectal end of the anal canal. - GOC:tfm - @@ -35627,21 +13900,7 @@ radial glial cells acting as neural progenitors throughout life. - A respiratory stem cell found at the junction of the terminal (conductive) bronchiole and the respiratory bronchiole. This cell types gives rise to alveolar cell types and Clara cells in response to lung injury. This cell type expresses markers Scgb1a1 and Sftpc. - tmeehan - 2011-06-21T03:26:08Z - BASC - basal epithelial cell of bronchioalveolar duct junction - cell - bronchioalveolar stem cell - - - - A respiratory stem cell found at the junction of the terminal (conductive) bronchiole and the respiratory bronchiole. This cell types gives rise to alveolar cell types and Clara cells in response to lung injury. This cell type expresses markers Scgb1a1 and Sftpc. - GOC:tfm - PMID:15960971 - @@ -35650,20 +13909,7 @@ radial glial cells acting as neural progenitors throughout life. - An amniotic stem cell is a mesenchymalstem cell extracted from amniotic fluid. Amniotic stem cells are able to differentiate into various tissue type such as skin, cartilage, cardiac tissue, nerves, muscle, and bone - tmeehan - 2011-06-21T03:55:39Z - cell - Not clear to me if amniotic stem cell is a different cell type from amnion mesenchymal stem cells. They are treated as distinct in the literature as isolations methods are different, so I will keep them as separate terms for now. - amniotic stem cell - - - - An amniotic stem cell is a mesenchymalstem cell extracted from amniotic fluid. Amniotic stem cells are able to differentiate into various tissue type such as skin, cartilage, cardiac tissue, nerves, muscle, and bone - GOC:tfm - PMID:20942606 - @@ -35671,19 +13917,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial fate stem cell derived form the amnion membrane. - tmeehan - 2011-06-21T04:06:17Z - cell - amniotic epithelial stem cell - - - - An epithelial fate stem cell derived form the amnion membrane. - GOC:tfm - PMID:20446274 - @@ -35691,19 +13925,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell of the esophageal gland proper. - tmeehan - 2011-07-08T02:16:51Z - FMA:256141 - cell - epithelial cell of esophageal gland proper - - - - An epithelial cell of the esophageal gland proper. - GOC:tfm - @@ -35711,20 +13933,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell of the esophageal cardiac gland that occurs both in the proximal and distal esophagus, within the lamina propia. - tmeehan - 2011-07-08T02:16:54Z - FMA:256143 - cell - epithelial cell of esophageal cardiac gland - - - - An epithelial cell of the esophageal cardiac gland that occurs both in the proximal and distal esophagus, within the lamina propia. - GOC:tfm - http://web.mac.com/wjkrause/iWeb/Histology/Blog/E3FA5916-1AA9-4885-B579-5051838D98CB.html - @@ -35732,19 +13941,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell of stratum corneum of esophageal epithelium that lacks keratin. - tmeehan - 2011-07-08T02:22:09Z - FMA:263148 - cell - nonkeratinized cell of stratum corneum of esophageal epithelium - - - - An epithelial cell of stratum corneum of esophageal epithelium that lacks keratin. - GOC:tfm - @@ -35752,19 +13949,7 @@ radial glial cells acting as neural progenitors throughout life. - An endothelial cell of viscerocranial mucosa that is part of the tympanic region of the viscerocranial mucosa. - tmeehan - 2011-07-08T02:25:44Z - FMA:70628 - cell - endo-epithelial cell of tympanic part of viscerocranial mucosa - - - - An endothelial cell of viscerocranial mucosa that is part of the tympanic region of the viscerocranial mucosa. - GOC:tfm - @@ -35772,119 +13957,37 @@ radial glial cells acting as neural progenitors throughout life. - An endocranial viscerocranial mucosa cell that is part of viscerocranial mucosa. - tmeehan - 2011-07-08T02:25:46Z - FMA:70629 - cell - endo-epithelial cell of pharyngotympanic part of viscerocranial mucosa - - - - An endocranial viscerocranial mucosa cell that is part of viscerocranial mucosa. - GOC:tfm - - - An ecto-epithelial cell of the buccal region of the viscerocranial mucosa. - tmeehan - 2011-07-08T02:34:12Z - FMA:70577 - cell - obsolete epithelial cell of buccal part of viscerocranial mucosa - true - - - - - An ecto-epithelial cell of the buccal region of the viscerocranial mucosa. - GOC:tfm - + - - An ecto-epithelial cell of the palatal region of the viscerocranial mucosa. - tmeehan - 2011-07-08T02:34:14Z - FMA:70580 - cell - obsolete epithelial cell of anterior palatal part of viscerocranial mucosa - true - - - - - An ecto-epithelial cell of the palatal region of the viscerocranial mucosa. - GOC:tfm - + - - An ecto-epithelial cell of the nasal region of the viscerocranial mucosa. - tmeehan - 2011-07-08T02:36:06Z - FMA:70554 - cell - obsolete epithelial cell of nasal part of viscerocranial mucosa - true - - - - - An ecto-epithelial cell of the nasal region of the viscerocranial mucosa. - GOC:tfm - + - - An ecto-epithelial cell of the gingival region of the viscerocranial mucosa. - tmeehan - 2011-07-08T02:36:11Z - FMA:70579 - cell - obsolete epithelial cell of gingival part of viscerocranial mucosa - true - - - - - An ecto-epithelial cell of the gingival region of the viscerocranial mucosa. - GOC:tfm - + - - An ecto-epithelial cell of the paranasal region of the viscerocranial mucosa. - tmeehan - 2011-07-08T02:38:18Z - FMA:70578 - cell - obsolete epithelial cell of paranasal sinus part of viscerocranial mucosa - true - - - - - An ecto-epithelial cell of the paranasal region of the viscerocranial mucosa. - GOC:tfm - + @@ -35892,26 +13995,7 @@ radial glial cells acting as neural progenitors throughout life. - An endothelial cell that is part of the venous sinus of spleen. This endothelial cell has an elongated, spindle-shaped, flattened morphology that is parallel to long axis of sinus. This cell type rests on a basement membrane interrupted by numerous narrow slits. - tmeehan - 2011-07-08T03:06:49Z - FMA:72140 - stave cell - cell - endothelial cell of venous sinus of spleen - - - - - An endothelial cell that is part of the venous sinus of spleen. This endothelial cell has an elongated, spindle-shaped, flattened morphology that is parallel to long axis of sinus. This cell type rests on a basement membrane interrupted by numerous narrow slits. - GOC:tfm - - - - - stave cell - FMA:62817 - + @@ -35920,23 +14004,7 @@ radial glial cells acting as neural progenitors throughout life. - A venule endothelial cell that is cubodial, expresses leukocyte-specific receptors, and allows for passage of lymphocytes into bloodstream. - tmeehan - 2011-07-08T03:14:10Z - FMA:67759 - HEV cell - endothelial cell of postcapillary venule of lymph node - cell - Markers expressed on HEV include: MAdCAM-1,PNAd (sulfated and glycosylated molecules, i.e. GlyCAM-1, CD34, endomucin, nepmucin), ICAM-1, ICAM-2,Fuc-TVII, beta 3GlcNAcT-3, GlcNAc6ST2,CCL21, CCL19, CXCL13, CXCL12, Autotaxin, DARC, angiomodulin, LRHG. - endothelial cell of high endothelial venule - - - - - A venule endothelial cell that is cubodial, expresses leukocyte-specific receptors, and allows for passage of lymphocytes into bloodstream. - GOC:tfm - PMID:20726857 - + @@ -35945,18 +14013,7 @@ radial glial cells acting as neural progenitors throughout life. - A endothelial cell of the venule that is squamous shaped. This is in contrast to the cubodial shape of high endothelial venule cells. - tmeehan - 2011-07-08T03:31:25Z - cell - squamous endothelial cell - - - - A endothelial cell of the venule that is squamous shaped. This is in contrast to the cubodial shape of high endothelial venule cells. - GOC:tfm - @@ -35964,19 +14021,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell of stratum corneum of esophageal epithelium. - tmeehan - 2011-07-08T03:46:35Z - FMA:70733 - cell - epithelial cell of stratum corneum of esophageal epithelium - - - - An epithelial cell of stratum corneum of esophageal epithelium. - GOC:tfm - @@ -35984,19 +14029,7 @@ radial glial cells acting as neural progenitors throughout life. - An epithelial cell of stratum spinosum of esophageal epithelium. - tmeehan - 2011-07-08T03:48:26Z - FMA:70732 - cell - epithelial cell of stratum spinosum of esophageal epithelium - - - - An epithelial cell of stratum spinosum of esophageal epithelium. - GOC:tfm - @@ -36004,19 +14037,7 @@ radial glial cells acting as neural progenitors throughout life. - A glandular epithelial cell of the endometrium. - tmeehan - 2011-07-08T03:54:08Z - FMA:86489 - cell - glandular cell of endometrium - - - - A glandular epithelial cell of the endometrium. - GOC:tfm - @@ -36025,19 +14046,7 @@ radial glial cells acting as neural progenitors throughout life. - A glandular epithelial cell of the esophagus. - tmeehan - 2011-07-08T03:55:57Z - FMA:86548 - cell - glandular cell of esophagus - - - - A glandular epithelial cell of the esophagus. - GOC:tfm - @@ -36046,19 +14055,7 @@ radial glial cells acting as neural progenitors throughout life. - A glandular epithelial cell of the large intestine. - tmeehan - 2011-07-08T04:03:01Z - FMA:87194 - cell - glandular cell of the large intestine - - - - A glandular epithelial cell of the large intestine. - GOC:tfm - @@ -36067,20 +14064,7 @@ radial glial cells acting as neural progenitors throughout life. - A glandular epithelial cell that is part of the stomach. - tmeehan - 2011-07-11T01:20:35Z - CALOHA:TS-1284 - FMA:86554 - cell - glandular cell of stomach - - - - A glandular epithelial cell that is part of the stomach. - GOC:tfm - @@ -36088,20 +14072,7 @@ radial glial cells acting as neural progenitors throughout life. - A luminal epithelial cell of mammary gland located in acinus of structure. - tmeehan - 2011-07-11T01:44:31Z - FMA:74505 - cell - Consider if synonymous with mammary alveolar cell CL:0002325. Some use this term to refer to the non-lactating cell type that gives rise to the lactating cell type. - luminal cell of acinus of lactiferous gland - - - - A luminal epithelial cell of mammary gland located in acinus of structure. - GOC:tfm - @@ -36109,19 +14080,7 @@ radial glial cells acting as neural progenitors throughout life. - A luminal cell of terminal ducts, i.e.e the terminal branch of a lactiferous duct which alveolar cells drain into. - tmeehan - 2011-07-11T01:44:33Z - FMA:87168 - cell - luminal cell of lactiferous terminal ductal lobular unit - - - - A luminal cell of terminal ducts, i.e.e the terminal branch of a lactiferous duct which alveolar cells drain into. - GOC:tfm - @@ -36129,21 +14088,7 @@ radial glial cells acting as neural progenitors throughout life. - A luminal epithelial cell of the lactiferous duct. This cuboidal epithelial cell expresses keratin-18 and is estrogen-receptor alpha positive. - tmeehan - 2011-07-11T01:44:48Z - FMA:74504 - FMA:74505 - cell - luminal cell of lactiferous duct - - - - A luminal epithelial cell of the lactiferous duct. This cuboidal epithelial cell expresses keratin-18 and is estrogen-receptor alpha positive. - GOC:tfm - PMID:19022771 - @@ -36151,19 +14096,7 @@ radial glial cells acting as neural progenitors throughout life. - A myocardial endocrine cell that is part of the atrium. - tmeehan - 2011-07-11T02:45:39Z - FMA:83389 - cell - myocardial endocrine cell of atrium - - - - A myocardial endocrine cell that is part of the atrium. - GOC:tfm - @@ -36171,20 +14104,7 @@ radial glial cells acting as neural progenitors throughout life. - A stem cell that can give rise to multiple cell types (i.e. smooth muscle, endothelial) in the developing heart. - tmeehan - 2011-07-11T03:15:38Z - cell - Discrepancy in develops from origins prevents me from making the assertion that cardioblasts give rise to all instances of cardiocytes as we state cardiac muscle cells develop from cardiac myoblast, which in turn develop from muscle stem cell. - cardioblast - - - - A stem cell that can give rise to multiple cell types (i.e. smooth muscle, endothelial) in the developing heart. - GOC:tfm - PMID:19745164 - @@ -36192,19 +14112,7 @@ radial glial cells acting as neural progenitors throughout life. - A fibrocyte of the cochlea that has specialized structural and molecular adaptions. - tmeehan - 2011-07-11T03:35:01Z - cell - otic fibrocyte - - - - A fibrocyte of the cochlea that has specialized structural and molecular adaptions. - GOC:tfm - PMID:18353863 - @@ -36212,27 +14120,7 @@ radial glial cells acting as neural progenitors throughout life. - An otic fibrocyte that underlies the spiral prominence and is part of a mesenchymal gap junction network that regulates ionic homeostasis of the endolymph. - tmeehan - 2011-07-11T03:40:40Z - type II otic fibrocyte - type II spiral ligament fibrocyte - cell - type 2 otic fibrocyte - - - - - An otic fibrocyte that underlies the spiral prominence and is part of a mesenchymal gap junction network that regulates ionic homeostasis of the endolymph. - GOC:tfm - PMID:18353863 - - - - - type II spiral ligament fibrocyte - MP:0004488 - + @@ -36240,21 +14128,7 @@ radial glial cells acting as neural progenitors throughout life. - An otic fibrocyte that resides above the stria vasularis and is part of a mesenchymal gap junction network that regulates ionic homeostasis of the endolymph. - tmeehan - 2011-07-11T03:40:42Z - type V otic fibrocyte - type V spiral ligament fibrocyte - cell - type 5 otic fibrocyte - - - - An otic fibrocyte that resides above the stria vasularis and is part of a mesenchymal gap junction network that regulates ionic homeostasis of the endolymph. - GOC:tfm - PMID:18353863 - @@ -36262,27 +14136,7 @@ radial glial cells acting as neural progenitors throughout life. - An otic fibrocyte that is lateral to the basilar membrane and anchoris it to the lateral wall. - tmeehan - 2011-07-11T03:40:46Z - type IV otic fibrocyte - type IV spiral ligament fibrocyte - cell - type 4 otic fibrocyte - - - - - An otic fibrocyte that is lateral to the basilar membrane and anchoris it to the lateral wall. - GOC:tfm - PMID:18353863 - - - - - type IV spiral ligament fibrocyte - MP:0004490 - + @@ -36290,27 +14144,7 @@ radial glial cells acting as neural progenitors throughout life. - An otic fibrocyte that lines the otic capsule. - tmeehan - 2011-07-11T03:40:50Z - type III otic fibrocyte - type III spiral ligament fibrocyte - cell - type 3 otic fibrocyte - - - - - An otic fibrocyte that lines the otic capsule. - GOC:tfm - PMID:18353863 - - - - - type III spiral ligament fibrocyte - MP:0004489 - + @@ -36318,27 +14152,7 @@ radial glial cells acting as neural progenitors throughout life. - An otic fibrocyte that underlies the stria vascularis and is part of a mesenchymal gap junction network that regulates ionic homeostasis of the endolymph. - tmeehan - 2011-07-11T03:39:27Z - type I otic fibrocyte - type I spiral ligament fibrocyte - cell - type 1 otic fibrocyte - - - - - An otic fibrocyte that underlies the stria vascularis and is part of a mesenchymal gap junction network that regulates ionic homeostasis of the endolymph. - GOC:tfm - PMID:18353863 - - - - - type I spiral ligament fibrocyte - MP:0004487 - + @@ -36346,19 +14160,7 @@ radial glial cells acting as neural progenitors throughout life. - An endothelial stalk cell is a specialized endothelial cell that follows behind the tip cell of an angiogenic sprout. - tmeehan - 2011-08-16T01:49:32Z - cell - endothelial stalk cell - - - - An endothelial stalk cell is a specialized endothelial cell that follows behind the tip cell of an angiogenic sprout. - GOC:tfm - PMID:21521739 - @@ -36366,20 +14168,7 @@ radial glial cells acting as neural progenitors throughout life. - A multi-fate stem cell that can give rise to different retinal cell types including rod and cone cells. - tmeehan - 2011-08-16T02:38:01Z - cell - retinal progenitor cell - - - - A multi-fate stem cell that can give rise to different retinal cell types including rod and cone cells. - GOC:tfm - PMID:20959166 - PMID:21148186 - @@ -36387,19 +14176,7 @@ radial glial cells acting as neural progenitors throughout life. - A skeletal muscle cell that is part of the tongue. - tmeehan - 2011-08-16T03:10:02Z - cell - tongue muscle cell - - - - A skeletal muscle cell that is part of the tongue. - GOC:tfm - PMID:18816858 - @@ -36407,19 +14184,7 @@ radial glial cells acting as neural progenitors throughout life. - A S. pombe mating type determined by the mat1-Mc and mat1-Mi on the mat1 locus. - tmeehan - 2011-08-16T03:20:53Z - H- cell - cell - H minus - - - - A S. pombe mating type determined by the mat1-Mc and mat1-Mi on the mat1 locus. - GOC:tfm - @@ -36427,18 +14192,7 @@ radial glial cells acting as neural progenitors throughout life. - A S. pombe cell type determined by mat1-Pc and mat1-Pi on the mat1 locus. - tmeehan - 2011-08-16T03:20:58Z - cell - H plus - - - - A S. pombe cell type determined by mat1-Pc and mat1-Pi on the mat1 locus. - GOC:tfm - @@ -36446,19 +14200,7 @@ radial glial cells acting as neural progenitors throughout life. - A neuroblast derived from a neural crest cell. - tmeehan - 2011-08-22T09:24:15Z - cell - neural crest derived neuroblast - - - - A neuroblast derived from a neural crest cell. - GOC:tfm - PMID:17407019 - @@ -36467,22 +14209,7 @@ radial glial cells acting as neural progenitors throughout life. - A regulatory T cell that has not encountered antigen. - tmeehan - 2011-08-25T03:17:21Z - naive regulatory T lymphocyte - naive regulatory T-cell - naive regulatory T-lymphocyte - cell - This cell type has been described as CD45RA-negative, but this doesn't fit with our current definition of naive T cell. - naive regulatory T cell - - - - A regulatory T cell that has not encountered antigen. - GOC:tfm - @@ -36491,20 +14218,7 @@ radial glial cells acting as neural progenitors throughout life. - A CD4-positive, CD25-positive alpha-beta regulatory T cell that has encountered antigen. - tmeehan - 2011-08-25T03:17:34Z - cell - Cell has been described as being CD45RA-positive in human, but this doesn't fit with our current definition memory T cell. - memory regulatory T cell - - - - A CD4-positive, CD25-positive alpha-beta regulatory T cell that has encountered antigen. - GOC:tfm - PMID:21739668 - @@ -36512,19 +14226,7 @@ radial glial cells acting as neural progenitors throughout life. - A lymphocyte found in adipose tissue that lacks lineage markers of other lymphocytes but is capable of mediating TH2 cytokine responses. This cell type is found in fat associated lymphoid clusters, proliferates in response to IL2 and produce large amounts of TH2 cytokines such as IL5, IL6 and IL13 - tmeehan - 2011-08-29T10:08:02Z - cell - natural helper lymphocyte - - - - A lymphocyte found in adipose tissue that lacks lineage markers of other lymphocytes but is capable of mediating TH2 cytokine responses. This cell type is found in fat associated lymphoid clusters, proliferates in response to IL2 and produce large amounts of TH2 cytokines such as IL5, IL6 and IL13 - GOC:tfm - PMID:20023630 - @@ -36533,20 +14235,7 @@ radial glial cells acting as neural progenitors throughout life. - A PP cell found in intestine. - tmeehan - 2011-09-27T11:59:01Z - cell - PP cell of intestine - - - - A PP cell found in intestine. - GOC:tfm - PMID:2420136 - PMID:728970 - @@ -36554,10 +14243,6 @@ radial glial cells acting as neural progenitors throughout life. - terryh - 2011-10-25T03:49:41Z - cell - kidney cortical cell @@ -36566,17 +14251,7 @@ radial glial cells acting as neural progenitors throughout life. - A CNS interneuron located in the spinal cord. - cell - Is_a interneuron, part_of UBERON:0002240. - spinal cord interneuron - - - - A CNS interneuron located in the spinal cord. - CL:CVS - @@ -36584,17 +14259,7 @@ radial glial cells acting as neural progenitors throughout life. - A non-terminally differentiated cell that originates from the neural crest and differentiates into an iridophore. - cell - Derived from UBERON:0002342 neural crest. - iridoblast - - - - A non-terminally differentiated cell that originates from the neural crest and differentiates into an iridophore. - CL:CVS - @@ -36602,16 +14267,7 @@ radial glial cells acting as neural progenitors throughout life. - A non-terminally differentiated cell that differentiates into a xanthophore. - cell - xanthoblast - - - - A non-terminally differentiated cell that differentiates into a xanthophore. - CL:CVS - @@ -36619,16 +14275,7 @@ radial glial cells acting as neural progenitors throughout life. - A non-terminally differentiated cell that originates from the neural crest and differentiates into a leucophore. - cell - leucoblast - - - - A non-terminally differentiated cell that originates from the neural crest and differentiates into a leucophore. - CL:CVS - @@ -36636,16 +14283,7 @@ radial glial cells acting as neural progenitors throughout life. - A non-terminally differentiated cell that originates from the neural crest and differentiates into an erythrophore. - cell - pigment erythroblast - - - - A non-terminally differentiated cell that originates from the neural crest and differentiates into an erythrophore. - CL:CVS - @@ -36653,16 +14291,7 @@ radial glial cells acting as neural progenitors throughout life. - A non-terminally differentiated cell that originates from the neural crest and differentiates into a cyanophore. - cell - cyanoblast - - - - A non-terminally differentiated cell that originates from the neural crest and differentiates into a cyanophore. - CL:CVS - @@ -36671,17 +14300,7 @@ radial glial cells acting as neural progenitors throughout life. - Specialized epithelial cells involved in the maintenance of osmotic homeostasis. They are characterized by abundant mitochondria and ion transporters. In amniotes, they are present in the renal system. In freshwater fish, ionocytes in the skin and gills help maintain osmotic homeostasis by absorbing salt from the external environment. - cell - ionocyte - - - - Specialized epithelial cells involved in the maintenance of osmotic homeostasis. They are characterized by abundant mitochondria and ion transporters. In amniotes, they are present in the renal system. In freshwater fish, ionocytes in the skin and gills help maintain osmotic homeostasis by absorbing salt from the external environment. - PMID:17555741 - PMID:19268451 - @@ -36690,32 +14309,7 @@ radial glial cells acting as neural progenitors throughout life. - Kolmer-Agduhr neurons are ciliated GABAergic neurons that contact the central canal of the spinal cord and have ipsilateral ascending axons. - KA cell - KA interneuron - KA neuron - Kolmer-Agduhr cell - cell - Kolmer-Agduhr neuron - - - - - Kolmer-Agduhr neurons are ciliated GABAergic neurons that contact the central canal of the spinal cord and have ipsilateral ascending axons. - PMID:18680739 - - - - - KA interneuron - PMID:15539490 - - - - - KA neuron - PMID:9634146 - + @@ -36723,16 +14317,7 @@ radial glial cells acting as neural progenitors throughout life. - An auditory hair cell located in the macula that is sensitive to auditory stimuli. - cell - macular hair cell - - - - An auditory hair cell located in the macula that is sensitive to auditory stimuli. - GO:cvs - @@ -36741,16 +14326,7 @@ radial glial cells acting as neural progenitors throughout life. - A cuboidal epithelial cell of the kidney which regulates sodium and potassium balance. The activity of sodium and potassium channels on the cells apical membrane is regulated by aldosterone and vasopressin. In mammals these cells are located in the renal collecting ducts. - cell - renal principal cell - - - - A cuboidal epithelial cell of the kidney which regulates sodium and potassium balance. The activity of sodium and potassium channels on the cells apical membrane is regulated by aldosterone and vasopressin. In mammals these cells are located in the renal collecting ducts. - CL:CVS - @@ -36760,18 +14336,7 @@ radial glial cells acting as neural progenitors throughout life. - A cuboidal epithelial cell of the kidney that regulates acid/base balance. - FMA:86560 - intercalated cell - cell - renal intercalated cell - - - - A cuboidal epithelial cell of the kidney that regulates acid/base balance. - CL:CVS - @@ -36779,16 +14344,7 @@ radial glial cells acting as neural progenitors throughout life. - A cuboidal epithelial cell of the kidney which secretes acid and reabsorbs base to regulate acid/base balance. - cell - renal alpha-intercalated cell - - - - A cuboidal epithelial cell of the kidney which secretes acid and reabsorbs base to regulate acid/base balance. - CL:CVS - @@ -36797,16 +14353,7 @@ radial glial cells acting as neural progenitors throughout life. - A ciliated epithelial cell with many cilium. - cell - multi-ciliated epithelial cell - - - - A ciliated epithelial cell with many cilium. - CL:CVS - @@ -36815,16 +14362,7 @@ radial glial cells acting as neural progenitors throughout life. - A ciliated epithelial cell with a single cilium. - cell - single ciliated epithelial cell - - - - A ciliated epithelial cell with a single cilium. - CL:CVS - @@ -36834,17 +14372,7 @@ radial glial cells acting as neural progenitors throughout life. - A non-sensory cell that extends from the basement membrane to the apical surface of the auditory epithelium and provides support for auditory hair cells. - cell - auditory epithelial support cell - - - - A non-sensory cell that extends from the basement membrane to the apical surface of the auditory epithelium and provides support for auditory hair cells. - CL:CVS - GOC:tfm - @@ -36852,53 +14380,19 @@ radial glial cells acting as neural progenitors throughout life. - An auditory epithelial support cell that surrounds the nerve fibers and synapses of the auditory inner hair cells. - FMA:79801 - cell - inner phalangeal cell - - - - An auditory epithelial support cell that surrounds the nerve fibers and synapses of the auditory inner hair cells. - CL:CVS - - - Obsolete. Use PO:0030007 from Plant Ontology instead. The apical cell is the upper cell formed after the first division of a plant zygote. - cell - replaced_by: PO:0030007 - obsolete apical cell - true - - - - - Obsolete. Use PO:0030007 from Plant Ontology instead. The apical cell is the upper cell formed after the first division of a plant zygote. - TAIR:TB - + - - Obsolete. Use PO:0002002 from Plant Ontology instead. The lower cell formed after the first division of a plant zygote. - cell - replaced_by: PO:0002002 - obsolete plant basal cell - true - - - - - Obsolete. Use PO:0002002 from Plant Ontology instead. The lower cell formed after the first division of a plant zygote. - TAIR:TB - + @@ -36906,16 +14400,7 @@ radial glial cells acting as neural progenitors throughout life. - A cell that secretes ghrelin, the peptide hormone that stimulates hunger. - cell - ghrelin secreting cell - - - - A cell that secretes ghrelin, the peptide hormone that stimulates hunger. - CL:curator - @@ -36923,18 +14408,7 @@ radial glial cells acting as neural progenitors throughout life. - Ghrelin secreting cells found in the found in the exocrine pancreas. - pancreatic E cell - cell - In mammals the endocrine pancreas is called the Islets of Langerhans. - pancreatic epsilon cell - - - - Ghrelin secreting cells found in the found in the exocrine pancreas. - PMID:14970313 - @@ -36942,19 +14416,7 @@ radial glial cells acting as neural progenitors throughout life. - Lymphatic progenitor cells. - Ceri - 2012-01-12T04:44:34Z - cell - Usually express Prox1, or prox1b. - lymphangioblast - - - - Lymphatic progenitor cells. - CL:CVS - @@ -36963,19 +14425,7 @@ radial glial cells acting as neural progenitors throughout life. - Mesenchymal derived lymphatic progenitor cells that give rise to the superficial lymphatics. - Ceri - 2012-01-12T05:01:22Z - cell - mesenchymal lymphangioblast - - - - Mesenchymal derived lymphatic progenitor cells that give rise to the superficial lymphatics. - PMID:15624319 - PMID:18430230 - @@ -36983,19 +14433,7 @@ radial glial cells acting as neural progenitors throughout life. - Lymphatic progenitor cells, derived from the veins, that give rise to lymphatic endothelial cells. - Ceri - 2012-01-12T05:21:09Z - parachordal lymphangioblast - cell - vascular lymphangioblast - - - - Lymphatic progenitor cells, derived from the veins, that give rise to lymphatic endothelial cells. - CL:CVS - @@ -37003,18 +14441,7 @@ radial glial cells acting as neural progenitors throughout life. - Cranial motor neuron which innervates muscles derived from the branchial (pharyngeal) arches. - PMID:14699587 - branchi motor neuron - special visceral motor neuron - branchiomotor neuron - - - - Cranial motor neuron which innervates muscles derived from the branchial (pharyngeal) arches. - ZFIN:CVS - @@ -37023,16 +14450,7 @@ radial glial cells acting as neural progenitors throughout life. - A motor neuron that innervates a skeletal muscle. These motor neurons are all excitatory and cholinergic. - somatic motor neuron - somatomotor neuron - - - - A motor neuron that innervates a skeletal muscle. These motor neurons are all excitatory and cholinergic. - ZFIN:CVS - @@ -37040,17 +14458,7 @@ radial glial cells acting as neural progenitors throughout life. - A motor neuron that synapses to parasympathetic neurons that innervate tear glands, sweat glands, and the smooth muscles and glands of the pulmonary, cardiovascular, and gastrointestinal systems. - general visceral motor neuron - Note that these neurons do not synapse directly onto muscles - visceromotor neuron - - - - A motor neuron that synapses to parasympathetic neurons that innervate tear glands, sweat glands, and the smooth muscles and glands of the pulmonary, cardiovascular, and gastrointestinal systems. - ZFIN:CVS - @@ -37058,17 +14466,7 @@ radial glial cells acting as neural progenitors throughout life. - Multi fate stem cell that gives rise to to both hepatocytes and cholangiocytes as descendants. - hepatoblast - - - - Multi fate stem cell that gives rise to to both hepatocytes and cholangiocytes as descendants. - GOC:CVS - PMID:18356246 - PMID:20483998 - @@ -37076,20 +14474,7 @@ radial glial cells acting as neural progenitors throughout life. - Skeletogenic cell that has the potential to develop into an ameloblast. Located in the inner enamel epithelium, these cells elongate, their nuclei shift distally (away from the dental papilla), and their cytoplasm becomes filled with organelles needed for synthesis and secretion of enamel proteins. - haendel - 2012-06-15T01:27:01Z - cell - unsure of neural crest contribution. In VSAO we have develops_from CL:0000008 - preameloblast - - - - Skeletogenic cell that has the potential to develop into an ameloblast. Located in the inner enamel epithelium, these cells elongate, their nuclei shift distally (away from the dental papilla), and their cytoplasm becomes filled with organelles needed for synthesis and secretion of enamel proteins. - GO_REF:0000034 - PMCID:PMC2737325 - @@ -37097,26 +14482,7 @@ radial glial cells acting as neural progenitors throughout life. - Cell that has the potential to form a skeletal cell type (e.g. cells in periosteum, cells in marrow) and produce extracellular matrix (often mineralized) and skeletal tissue (often mineralized). - haendel - 2012-06-15T02:51:27Z - scleroblast - cell - Needs logical definition. Should be capable_of skeletal system morphogenesis? or skeletal tissue development? needs to be added to GO. NOTES:a cell type of the early embryo (see also: mesenchymal cells) that will give rise to mineralized connective tissue. Scleroblasts can differentiate into osteoblasts (bone-forming cells), chondroblasts (cartilage-forming cells), odontoblasts (dentin-forming cells), ameloblasts (enamel-forming cells). The mesenchymal cells developing into osteoblasts and chondroblasts are derived from the mesoderm. Those developing into odontoblasts are neural crest cells. Those developing into ameloblasts are derived from the ectoderm. (http://www.copewithcytokines.de/cope.cgi?key=scleroblasts) - skeletogenic cell - - - - - Cell that has the potential to form a skeletal cell type (e.g. cells in periosteum, cells in marrow) and produce extracellular matrix (often mineralized) and skeletal tissue (often mineralized). - GO_REF:0000034 - - - - - scleroblast - GO_REF:0000034 - + @@ -37124,18 +14490,7 @@ radial glial cells acting as neural progenitors throughout life. - Skeletogenic cell that has the potential to develop into a cementoblast. - haendel - 2012-06-15T04:37:13Z - cell - precementoblast - - - - Skeletogenic cell that has the potential to develop into a cementoblast. - GO_REF:0000034 - @@ -37143,18 +14498,7 @@ radial glial cells acting as neural progenitors throughout life. - Skeletogenic cell that has the potential to form an odontoblast, deposits predentine, and arises from a cranial neural crest cell. - haendel - 2012-06-15T05:15:11Z - cell - preodontoblast - - - - Skeletogenic cell that has the potential to form an odontoblast, deposits predentine, and arises from a cranial neural crest cell. - GO_REF:0000034 - @@ -37162,18 +14506,7 @@ radial glial cells acting as neural progenitors throughout life. - Cell that is part of the neural crest region of the neuroepithelium, prior to migration. Note that not all premigratory neural crest cells may become migratory neural crest cells. - haendel - 2012-06-27T08:27:35Z - cell - premigratory neural crest cell - - - - Cell that is part of the neural crest region of the neuroepithelium, prior to migration. Note that not all premigratory neural crest cells may become migratory neural crest cells. - UBERONREF:0000002 - @@ -37181,19 +14514,7 @@ radial glial cells acting as neural progenitors throughout life. - Cell that is part of the notochord. - haendel - 2012-06-27T08:47:31Z - cell - NOTE: TO DO, notochord development still needs work. - notochordal cell - - - - Cell that is part of the notochord. - GO_REF:0000034 - @@ -37201,19 +14522,7 @@ radial glial cells acting as neural progenitors throughout life. - Mesodermal cell that is axially located and gives rise to the cells of the notochord. - haendel - 2012-06-27T08:52:41Z - axial mesodermal cell - cell - chordamesodermal cell - - - - Mesodermal cell that is axially located and gives rise to the cells of the notochord. - GO_REF:0000034 - @@ -37221,18 +14530,7 @@ radial glial cells acting as neural progenitors throughout life. - Notochordal cell that is part of the outer epithelium of the notochord and surrounds the vacuolated notochord cells. - haendel - 2012-06-27T09:26:37Z - cell - notochordal sheath cell - - - - Notochordal cell that is part of the outer epithelium of the notochord and surrounds the vacuolated notochord cells. - CL:MAH - @@ -37240,32 +14538,7 @@ radial glial cells acting as neural progenitors throughout life. - Notochordal cell that is inner portion of the notochord and becomes vacuolated as development proceeds. - haendel - 2012-06-27T09:29:30Z - chordablast - chordoblast - cell - notochordal vacuole cell - - - - - Notochordal cell that is inner portion of the notochord and becomes vacuolated as development proceeds. - CL:MAH - - - - - chordablast - GO_REF:0000034 - - - - - chordoblast - PMID:14574572 - + @@ -37273,18 +14546,7 @@ radial glial cells acting as neural progenitors throughout life. - Skeletogenic cell that has the potential to develop into a chondroblast; and arises from neural crest, meseosdermal and notochordal and connective tissue cells. - haendel - 2012-06-27T10:44:01Z - cell - prechondroblast - - - - Skeletogenic cell that has the potential to develop into a chondroblast; and arises from neural crest, meseosdermal and notochordal and connective tissue cells. - GO_REF:0000034 - @@ -37292,19 +14554,7 @@ radial glial cells acting as neural progenitors throughout life. - Skeletogenic cell that has the potential to transform into an osteoblast, and develops from neural crest or mesodermal cells. - haendel - 2012-06-27T10:57:21Z - osteoprogenitor cell - cell - preosteoblast - - - - Skeletogenic cell that has the potential to transform into an osteoblast, and develops from neural crest or mesodermal cells. - GO_REF:0000034 - @@ -37313,18 +14563,7 @@ radial glial cells acting as neural progenitors throughout life. - Neuron that is part of the enteric nervous system. - haendel - 2012-06-28T08:20:31Z - cell - enteric neuron - - - - Neuron that is part of the enteric nervous system. - CL:MAH - @@ -37332,17 +14571,7 @@ radial glial cells acting as neural progenitors throughout life. - Odontoblast that non-terminally differentiated, located in the odontogenic papilla and dentine tissue, and transforms from a odontoblast cell. - cl - non-terminally differentiated odontoblast - - - - Odontoblast that non-terminally differentiated, located in the odontogenic papilla and dentine tissue, and transforms from a odontoblast cell. - GO_REF:0000034 - PSPUB:0000170 - @@ -37350,65 +14579,19 @@ radial glial cells acting as neural progenitors throughout life. - Odontoblast that is terminally differentiated and derived from an odontogenic papilla and associated with dentine. - cl - terminally differentiated odontoblast - - - - Odontoblast that is terminally differentiated and derived from an odontogenic papilla and associated with dentine. - GO_REF:0000034 - - - OBSOLETE: A cultured cell that has been passaged at least one time in culture. - - haendel - 2012-11-28T11:54:59Z - passaged cultured cell - cell - Obsoleted in July 2013 and replaced by the CLO 'cell line cell' class, as a result of CLO-OBI-CL alignment efforts. - -Covers cells actively being cultured or stored in a quiescent state for future use. - obsolete cell line cell - true - - - - - OBSOLETE: A cultured cell that has been passaged at least one time in culture. - ReO:mhb - + - - OBSOLETE: A cell line cell that is expected to be capable of replicating a limited number of times in culture before undergoing senescence. Mortal cell line cells cannot be propagated indefinitely (as immortal cell line cells can). - - haendel - 2012-11-28T11:56:20Z - finite cell line cell - cell - primary cell line cell - Obsoleted in July 2013 and replaced by the CLO 'mortal cell line cell' class, as a result of CLO-OBI-CL alignment efforts. - -Covers cells actively being cultured or stored in a quiescent state for future use. - obsolete mortal cell line cell - true - - - - - OBSOLETE: A cell line cell that is expected to be capable of replicating a limited number of times in culture before undergoing senescence. Mortal cell line cells cannot be propagated indefinitely (as immortal cell line cells can). - ReO:mhb - + @@ -37416,19 +14599,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Muscle precursor cell that is adjacent to the notochord and part of the presomitic mesoderm. - haendel - 2012-12-30T12:43:15Z - cell - In teleosts, adaxial cells give rise to slow muscle myoblasts. - adaxial cell - - - - Muscle precursor cell that is adjacent to the notochord and part of the presomitic mesoderm. - PMID:8951054 - @@ -37440,17 +14611,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An epidermal cell with apical microvilli or a single apical projection have synaptic associations with nerve fibres in the epidermis. - haendel - Taxon specificity not yet fully known, but are known in anuran larvae but not in adults. - Stiftchenzellen - - - - An epidermal cell with apical microvilli or a single apical projection have synaptic associations with nerve fibres in the epidermis. - PMID:1087183 - @@ -37460,17 +14621,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Ciliated cell of the embryonic epidermis and functions in embryonic movements. - haendel - Taxon specificity not clear -present in embryonic anurans. - epidermal ciliary cell - - - - Ciliated cell of the embryonic epidermis and functions in embryonic movements. - PMCID:PMC3046089 - @@ -37478,9 +14629,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - haendel - taxon specificity not clear. Appears in early larval stages of anurans and persists after metamorphosis. - epidermal mucus secreting cell @@ -37489,16 +14637,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Characteristic early embryonic cell with a bottle or flask shape that is first to migrate inwards at the blastopore during gastrulation in amphibians. - haendel - bottle cell - - - - Characteristic early embryonic cell with a bottle or flask shape that is first to migrate inwards at the blastopore during gastrulation in amphibians. - PMID:3197630 - @@ -37507,23 +14646,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Secretory cell that produces a chemical mixture that triggers antipredator behavior. The substance is released only upon disruption of the epidermis. [Behavior of teleost fishes, second edition, edited by Pitcher, 1992] - haendel - club cell - alarm substance cell - - - - - Secretory cell that produces a chemical mixture that triggers antipredator behavior. The substance is released only upon disruption of the epidermis. [Behavior of teleost fishes, second edition, edited by Pitcher, 1992] - ISBN-10:0412429403 - - - - - club cell - ISBN-10:0412429403 - + @@ -37531,18 +14654,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A specialized pore forming cell of the follicle, located adjacent to the animal pole of the oocyte. The micropylar cell makes the single micropyle (pore) through the chorion through which the sperm fertilizes the egg. - haendel - plug cell - micropylar cell - - - - A specialized pore forming cell of the follicle, located adjacent to the animal pole of the oocyte. The micropylar cell makes the single micropyle (pore) through the chorion through which the sperm fertilizes the egg. - PMID:18582455 - ZFA:0005239 - @@ -37550,16 +14662,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Epidermal cell rich in mitochondria. In amphibians, appears during metamorphosis. - haendel - flask cell - - - - Epidermal cell rich in mitochondria. In amphibians, appears during metamorphosis. - DOI:10.1007/BF00717048 - @@ -37567,15 +14670,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Any muscle cell in which the fibers are not organised into sarcomeres. - non-striated muscle cell - - - - Any muscle cell in which the fibers are not organised into sarcomeres. - GOC:DOS - @@ -37583,15 +14678,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Any hematopoietic cell that is a precursor of some other hematopoietic cell type. - hematopoietic precursor cell - - - - Any hematopoietic cell that is a precursor of some other hematopoietic cell type. - GOC:dos - @@ -37600,16 +14687,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A transversely striated, synctial cell of skeletal muscle. It is formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. - skeletal muscle fiber - - - - A transversely striated, synctial cell of skeletal muscle. It is formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. - GOC:tfm - ISBN:0323052908 - @@ -37618,16 +14696,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A myotube that is part of some somatic muscle. Examples include arthropod somatic muscle cells. - somatic muscle myotube - - - - A myotube that is part of some somatic muscle. Examples include arthropod somatic muscle cells. - PMID:22274696 - PMID:8720463 - @@ -37635,15 +14704,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A muscle cell that is part of some somatic muscle. - somatic muscle cell - - - - A muscle cell that is part of some somatic muscle. - GOC:dos - @@ -37653,15 +14714,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A somatic muscle cell that is oblquely striated. Examples include the somatic muscles of nematodes. - obliquely striated somatic muscle cell - - - - A somatic muscle cell that is oblquely striated. Examples include the somatic muscles of nematodes. - PMID:8720463 - @@ -37669,16 +14722,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A myoblast that detemines the properties (size, shape and attachment to the epidermis) of a `somatic muscle myotube` (CL:0008003) . It develops into a somatic muscle myotube via fusion with `fusion component myoblasts` (CL:0000621). - cell - muscle founder cell - - - - A myoblast that detemines the properties (size, shape and attachment to the epidermis) of a `somatic muscle myotube` (CL:0008003) . It develops into a somatic muscle myotube via fusion with `fusion component myoblasts` (CL:0000621). - PMID:22274696 - @@ -37686,15 +14730,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A muscle cell that is part of some visceral muscle - visceral muscle cell - - - - A muscle cell that is part of some visceral muscle - GOC:dos - @@ -37703,15 +14739,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A visceral muscle cell that is striated. Examples include the visceral muscle cells of arhtropods. - striated visceral muscle cell - - - - A visceral muscle cell that is striated. Examples include the visceral muscle cells of arhtropods. - GOC:dos - @@ -37719,15 +14747,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A visceral muscle that is transversely striated. Examples include the visceral muscle cells of arthropods. - transversely striated visceral muscle cell - - - - A visceral muscle that is transversely striated. Examples include the visceral muscle cells of arthropods. - GOC:dos - @@ -37736,15 +14756,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cranial motor neuron whose soma is located in the midbrain andor hindbrain and which innervates the skeletal muscles of the eye or tongue. - cranial somatomotor neuron - - - - A cranial motor neuron whose soma is located in the midbrain andor hindbrain and which innervates the skeletal muscles of the eye or tongue. - PMID:14699587 - @@ -37753,16 +14765,8 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A skeletal muscle satellite cell that divides by stem cell division. A proportion of this population undergoes symmetric stem cell division, producing two skeletal muscle satellite stem cells. The rest undergo asymmetric stem cell division - retaining their identity while budding off a daughter cell that differentiates into an adult skeletal muscle myoblast. - cell - skeletal muscle satellite stem cell + - - - - A skeletal muscle satellite cell that divides by stem cell division. A proportion of this population undergoes symmetric stem cell division, producing two skeletal muscle satellite stem cells. The rest undergo asymmetric stem cell division - retaining their identity while budding off a daughter cell that differentiates into an adult skeletal muscle myoblast. - PMID:23303905 - @@ -37770,17 +14774,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A skeletal muscle satellite cell that is mitotically quiescent. These cells are wedge shaped and have a large nuclear to cytoplasmic ratio with few organelles, a small nucleus and condensed interphase chromatin. Satellite cells typically remain in this state until activated following muscle damage. - cell - quiescent skeletal muscle satellite cell - - - - A skeletal muscle satellite cell that is mitotically quiescent. These cells are wedge shaped and have a large nuclear to cytoplasmic ratio with few organelles, a small nucleus and condensed interphase chromatin. Satellite cells typically remain in this state until activated following muscle damage. - PMID:21849021 - PMID:23303905 - @@ -37789,15 +14783,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A visceromotor motor neuron whose soma is located in the hindbrain, and which synapses to parasympathetic neurons that innervate tear glands, sweat glands, and the smooth muscles of the head. - cranial visceromotor neuron - - - - A visceromotor motor neuron whose soma is located in the hindbrain, and which synapses to parasympathetic neurons that innervate tear glands, sweat glands, and the smooth muscles of the head. - PMID:14699587 - @@ -37805,9 +14791,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A motor neuron that is capable of directly inducing muscle contraction. - In vertebrates, all motor neurons are excitatory, but various types of inhibitory motor neurons exist in invertebrates. - excitatory motor neuron @@ -37816,9 +14799,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A motor neuron that is capable of directly inhibiting muscle contraction. - In vertebrates, all motor neurons are excitatory, but various types of inhibitory motor neurons exist in invertebrates. - inhibitory motor neuron @@ -37827,17 +14807,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A skeletal muscle cell that has become mitotically active - typically following muscle damage. - cell - activated skeletal muscle satellite cell - - - - A skeletal muscle cell that has become mitotically active - typically following muscle damage. - PMID:21849021 - PMID:23303905 - @@ -37846,24 +14816,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A skeletal muscle myoblast that is part of a skeletal mucle. These cells are formed following acivation and division of skeletal muscle satellite cells. They form a transient population that is lost when they fuse to form skeletal muscle fibers. - myogenic precursor cell - cell - The vast majority of these cells develop from skeletal muscle satellite cells, although there are some reports of other origins. - adult skeletal muscle myoblast - - - - - A skeletal muscle myoblast that is part of a skeletal mucle. These cells are formed following acivation and division of skeletal muscle satellite cells. They form a transient population that is lost when they fuse to form skeletal muscle fibers. - PMID:23303905 - - - - - myogenic precursor cell - PMID:23303905 - + @@ -37871,9 +14824,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A myoblast that is commited to developing into a somatic muscle. - cell - somatic muscle myoblast @@ -37883,9 +14833,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A non-polarised cell precursor cell that is part of some mesenchyme, is associated with the cell matrix but is not connected to other cells and is capable of migration. - mesenchyme cell - mesenchymal cell @@ -37894,17 +14841,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A skeletal muscle satellite cell that undergoes symmetric division to produce two adult skeleltal muscle myoblasts. - cell - skeletal muscle satellite myogenic cell - - - - A skeletal muscle satellite cell that undergoes symmetric division to produce two adult skeleltal muscle myoblasts. - GOC:dos - PMID:23303905 - @@ -37912,7 +14849,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - anterior lateral line ganglion neuron @@ -37922,26 +14858,13 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A mesenchymal cell of the endocardial cushion. These cells develop via an epithelial to mesenchymal transition when endocardial cells break cell-to-cell contacts and migrate into the cardiac jelly. Cells from this population form the heart septa and valves. - endocardial cushion cell - - - - A mesenchymal cell of the endocardial cushion. These cells develop via an epithelial to mesenchymal transition when endocardial cells break cell-to-cell contacts and migrate into the cardiac jelly. Cells from this population form the heart septa and valves. - PMID:18816864 - - - - Duplicate term. - cardiac fibroblast - true - + @@ -37949,16 +14872,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An endocrine cell that is part of the pancreas. - cell - pancreatic endocrine cell - - - - An endocrine cell that is part of the pancreas. - GOC:dos - @@ -37967,15 +14881,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A neuron that release noradrenaline (noriphinephrine) as a neurotransmitter. - noradrenergic neuron - - - - A neuron that release noradrenaline (noriphinephrine) as a neurotransmitter. - GOC:dos - @@ -37983,16 +14889,57 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An epithelial cell that is part of the epithelium of a tracheal tube in an open tracheal system, such as that found in insects. - cell - open tracheal system tracheocyte - - - - An epithelial cell that is part of the epithelium of a tracheal tube in an open tracheal system, such as that found in insects. - GOC:dos - + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + @@ -38001,28 +14948,14 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A sensory neuron of the spinal nerve that senses body position and sends information about how much the muscle is stretched to the spinal cord. - spinal sensory neuron - sensory neuron of spinal nerve - - - - A sensory neuron of the spinal nerve that senses body position and sends information about how much the muscle is stretched to the spinal cord. - GOC:nv - GOC:pr - - - Any cell in the compound eye, a light sensing organ composed of ommatidia. - GOC:pr - PMID:12021768 - compound eye retinal cell + @@ -38031,10 +14964,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Any cell participating in the inflammatory response to a foreign substance, e.g. neutrophil, macrophage. - GOC:pr - http://en.wikipedia.org/wiki/Inflammatory_response - inflammatory cell @@ -38043,10 +14972,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Any cell in the midgut (middle subdivision of a digestive tract) of a larva. - GOC:pr - http://en.wikipedia.org/wiki/Insect#Midgut - larval midgut cell @@ -38055,17 +14980,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Any cell in the retina, the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates. - PMID:10702418 - cell - retinal cell - - - - Any cell in the retina, the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates. - GOC:pr - @@ -38073,10 +14988,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Any cell in a salivary gland. - GOC:pr - http://en.wikipedia.org/wiki/Salivary_gland - salivary gland cell @@ -38085,15 +14996,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A hair follicle matrix region cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the hair bulb to become the hair medulla cortex and hair root sheath. - keratinized cell of hair follicle - - - - A hair follicle matrix region cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the hair bulb to become the hair medulla cortex and hair root sheath. - - @@ -38102,10 +15005,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - a stromal cell that is part_of a bone marrow - GOC:cjm - bone marrow stromal cell - stromal cell of bone marrow @@ -38114,10 +15013,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - a epithelial cell that is part_of a umbilical artery - GOC:cjm - umbilical artery epithelial cell - epithelial cell of umbilical artery @@ -38126,11 +15021,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - a epithelial cell that is part_of a alveolus of lung - GOC:cjm - alveolus of lung epithelial cell - May be merged with pneumocyte in future - epithelial cell of alveolus of lung @@ -38140,10 +15030,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - a mononuclear cell that is part_of a bone marrow - GOC:cjm - bone marrow mononuclear cell - mononuclear cell of bone marrow @@ -38152,16 +15038,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A specialized cardiomyocyte that transmit signals from the AV node to the cardiac Purkinje fibers. - AV bundle cell - atrioventricular bundle cell - - - - A specialized cardiomyocyte that transmit signals from the AV node to the cardiac Purkinje fibers. - GOC:mtg_heart - @@ -38170,7 +15047,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cardiac blood vessel endothelial cell @@ -38179,7 +15055,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - His-Purkinje system cell @@ -38189,7 +15064,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cardiac endothelial cell @@ -38199,8 +15073,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - camera type eye photoreceptor cell - camera-type eye photoreceptor cell @@ -38210,7 +15082,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cerebellar stellate cell @@ -38218,11 +15089,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - - - a GABAergic interneuron that is part_of a cerebral cortex - cerebral cortex GABAergic interneuron @@ -38231,8 +15098,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - a neuron that is part_of a cerebral cortex - cerebral cortex neuron @@ -38241,8 +15106,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - light pinealocyte - type I pinealocyte @@ -38251,8 +15114,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - dark pinealocyte - type II pinealocyte @@ -38261,17 +15122,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A highly specialized cell type exclusive to and forming neuroepithelium of the Saccus vasculosus, covering the caudal diverticulum of the infundibular recess. - Editor note: remember to link to Saccus vasculosus in next uberon release - coronet cell - - - - A highly specialized cell type exclusive to and forming neuroepithelium of the Saccus vasculosus, covering the caudal diverticulum of the infundibular recess. - GOC:mr - PMID:17595538 - @@ -38279,16 +15130,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell with a flagellum surrounded by a collar of microvilli. The motion of the flagellum draws water past the microvilli, serving either a feeding or sensory function. Collar cells are found in multiple animals, including sponges, echinoderms, and cnidarians. They are also found outside animals in the choanoflagellates. Although collar cells are superficially similar, their cytoskeletal structure and functional biology are different in different groups of organisms. - cell - collar cell - - - - A cell with a flagellum surrounded by a collar of microvilli. The motion of the flagellum draws water past the microvilli, serving either a feeding or sensory function. Collar cells are found in multiple animals, including sponges, echinoderms, and cnidarians. They are also found outside animals in the choanoflagellates. Although collar cells are superficially similar, their cytoskeletal structure and functional biology are different in different groups of organisms. - PMID:25840473 - @@ -38297,7 +15139,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cardiac glial cell @@ -38306,8 +15147,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cell - cardiac myoblast @@ -38317,7 +15156,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - cardiac neuron @@ -38327,16 +15165,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A CNS interneuron located in the dorsal horn of the spinal cord. - dorsal spinal cord interneuron - dorsal horn interneuron - - - - A CNS interneuron located in the dorsal horn of the spinal cord. - GOC:nv - @@ -38345,15 +15174,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement. - spinal cord motor neuron - - - - A motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement. - GOC:nv - @@ -38361,16 +15182,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A motor neuron that is generated only on limb levels and send axons into the limb mesenchyme. - Need to MIREOT in 'spinal cord lateral column' from Uberon - lateral motor column neuron - - - - A motor neuron that is generated only on limb levels and send axons into the limb mesenchyme. - GOC:nv - @@ -38380,17 +15192,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A neurosecretory neuron residing mainly in the hypothalamic supraoptic and paraventricular nuclei and in a number of smaller accessory cell groups between these two nuclei, that secretes the hormones oxytocin and vasopressin. - magnocellular neuron - magnocellular neurosecretory cell (duplicate class) - - - - A neurosecretory neuron residing mainly in the hypothalamic supraoptic and paraventricular nuclei and in a number of smaller accessory cell groups between these two nuclei, that secretes the hormones oxytocin and vasopressin. - GOC:nv - MP:0009467 - @@ -38398,17 +15200,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A vetebrate lens cell that is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye. - lens fibre cell - lens fiber cell - - - - A vetebrate lens cell that is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye. - GO:0070307 - GOC:nv - @@ -38417,15 +15209,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An interneuron that uses GABA as a vesicular neurotransmitter. - GABAergic interneuron - - - - An interneuron that uses GABA as a vesicular neurotransmitter. - GOC:nv - @@ -38435,15 +15219,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - An inhibitory GABAergic interneuron found in the cerebellar cortex. - Lugaro cell - - - - An inhibitory GABAergic interneuron found in the cerebellar cortex. - GOC:nv - @@ -38451,19 +15227,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell in the area of mesoderm in the neurulating embryo that flanks and forms simultaneously with the neural tube. The cells of this region give rise to somites. - paraxial mesoderm cell - somitic mesoderm cell - presomitic mesoderm cell - paraxial cell - - - - A cell in the area of mesoderm in the neurulating embryo that flanks and forms simultaneously with the neural tube. The cells of this region give rise to somites. - GOC:NV - PMID:11687492 - @@ -38471,16 +15235,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A hemocyte derived from head mesoderm, which enters the hemolymph as acirculating cell. - embryonic hemocyte - - - - A hemocyte derived from head mesoderm, which enters the hemolymph as acirculating cell. - GOC:NV - PMID:17967061 - @@ -38488,16 +15243,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A plasmatocyte derived from head mesoderm. - embryonic plasmatocyte - - - - A plasmatocyte derived from head mesoderm. - GOC:NV - PMID:17967061 - @@ -38505,16 +15251,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell derived from the mesoderm that is found at the periphery of the embryo. - lateral mesodermal cell - - - - A cell derived from the mesoderm that is found at the periphery of the embryo. - GOC:NV - PMID:9169844 - @@ -38522,16 +15259,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell derived from the mesoderm that is located between the paraxial mesoderm and the lateral plate. - intermediate mesodermal cell - - - - A cell derived from the mesoderm that is located between the paraxial mesoderm and the lateral plate. - GOC:NV - ISBN:978-0-87969-707-5 - @@ -38540,17 +15268,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A cell of the neural crest. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesynchymal transition and delamination to form migratory neural crest cells. - cell - neural crest cell - - - - A cell of the neural crest. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesynchymal transition and delamination to form migratory neural crest cells. - https://orcid.org/0000-0001-5208-3432 - https://orcid.org/0000-0002-9900-7880 - @@ -38558,18 +15276,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Neuron that secretes the neurotransmitter galanin. - galanergic neuron - - - - Neuron that secretes the neurotransmitter galanin. - GOC:NV - PMID:23159249 - ZFIN:CVS - ZFIN:YB - @@ -38577,15 +15284,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Cells of the uterine chorion that acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer. - chorionic trophoblast cell - - - - Cells of the uterine chorion that acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer. - GOC:NV - @@ -38593,16 +15292,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Parasympathetic neurons are part of the parasympathetic nervous sysem and the cell bodies lie in the brain and sacral region of the spinal cord. The neurons are mainly cholinergic. - parasympathetic neuron - - - - Parasympathetic neurons are part of the parasympathetic nervous sysem and the cell bodies lie in the brain and sacral region of the spinal cord. The neurons are mainly cholinergic. - GOC:NV - isbn:0080923437 - @@ -38610,16 +15300,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Sympathetic neurons are part of the sympathetic nervous system and are primarily adrenergic producing the neurotransmitter noradrenalin along with other neuropeptides. - sympathetic neuron - - - - Sympathetic neurons are part of the sympathetic nervous system and are primarily adrenergic producing the neurotransmitter noradrenalin along with other neuropeptides. - GOC:NV - isbn:0080923437 - @@ -38628,21 +15309,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - A type of interneuron in the retinal inner nuclear layer which -carries information from the inner plexiform layer and the outer -plexiform layer. - Need to MIREOT retinal inner nuclear layer (part of) - interplexiform cell - - - - A type of interneuron in the retinal inner nuclear layer which -carries information from the inner plexiform layer and the outer -plexiform layer. - GOC:NV - PMID:12771169 - @@ -38651,21 +15318,7 @@ plexiform layer. - A type of interneuron in the retinal inner nuclear layer which -carries information from the inner plexiform layer and the outer -plexiform layer, using dopamine. - This type of cell is found in Danio rerio. - dopamanergic interplexiform cell - - - - A type of interneuron in the retinal inner nuclear layer which -carries information from the inner plexiform layer and the outer -plexiform layer, using dopamine. - GOC:NV - PMID:12771169 - @@ -38674,21 +15327,7 @@ plexiform layer, using dopamine. - A type of interneuron in the retinal inner nuclear layer which -carries information from the inner plexiform layer and the outer -plexiform layer using GABA. - This type of cell is found in many mammals. - GABAnergic interplexiform cell - - - - A type of interneuron in the retinal inner nuclear layer which -carries information from the inner plexiform layer and the outer -plexiform layer using GABA. - GOC:NV - PMID:12771169 - @@ -38697,20 +15336,7 @@ plexiform layer using GABA. - Astrocyte-like radial glial cell that extends vertically throughout the retina, with the nucleus are usually in the middle of the inner nuclear layer. - - Muller glia - Müller cell - Muller cell - - - - Astrocyte-like radial glial cell that extends vertically throughout the retina, with the nucleus are usually in the middle of the inner nuclear layer. - - GOC:NV - PMID:21911394 - @@ -38718,16 +15344,7 @@ plexiform layer using GABA. - Epithelial cell that is part of the colon epithelium. - colonic epithelial cell - colon epithelial cell - - - - Epithelial cell that is part of the colon epithelium. - GOC:NV - @@ -38736,17 +15353,7 @@ plexiform layer using GABA. - A neuron that releases hypocretin as a neurotransmitter. - orexin - hypocretin-secreting neuron - - - - A neuron that releases hypocretin as a neurotransmitter. - GOC:NV - PMID:23848055 - @@ -38755,16 +15362,7 @@ plexiform layer using GABA. - Neuron that secretes histamine. - histaminergic neuron - - - - Neuron that secretes histamine. - GOC:NV - PMID:22677810 - @@ -38773,18 +15371,7 @@ plexiform layer using GABA. - Neuroendocrine cells that are born in the nasal placode during embryonic development and migrate through the nose and forebrain to the hypothalamus, where they regulate reproduction. - GnRH neuron - GnRH-secreting neuron - gonadotropin releasing neuron - - - - Neuroendocrine cells that are born in the nasal placode during embryonic development and migrate through the nose and forebrain to the hypothalamus, where they regulate reproduction. - GOC:NV - PMID:21828096 - @@ -38793,16 +15380,7 @@ plexiform layer using GABA. - Neurons part of the hypothalamic supraoptic and paraventricular nuclei that secrete the hormones, oxytocin and vasopressin into the systemic circulation from the posterior pituitary gland. - magnocellular neurosecretory cell - - - - Neurons part of the hypothalamic supraoptic and paraventricular nuclei that secrete the hormones, oxytocin and vasopressin into the systemic circulation from the posterior pituitary gland. - GOC:NV - PMID:10711808 - @@ -38810,15 +15388,7 @@ plexiform layer using GABA. - Neuron found in the spriral ganglion. - spiral ganglion neuron - - - - Neuron found in the spriral ganglion. - GOC:NV - @@ -38827,16 +15397,7 @@ plexiform layer using GABA. - A segmented neutrophilic cell of the bone marrow reserve pool that expresses CD11b (integrin alpha-M) and high levels of CD16 (low affinity immunoglobulin gamma Fc region receptor III) on its cell surface. - segmented neutrophil of bone marrow - - - - A segmented neutrophilic cell of the bone marrow reserve pool that expresses CD11b (integrin alpha-M) and high levels of CD16 (low affinity immunoglobulin gamma Fc region receptor III) on its cell surface. - PMID:11138622 - PMID:15514007 - @@ -38844,16 +15405,7 @@ plexiform layer using GABA. - A cell that, by division or terminal differentiation, can give rise to other cell types. - Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell. - precursor cell - - - - A cell that, by division or terminal differentiation, can give rise to other cell types. - GOC:dos - @@ -38862,11 +15414,6 @@ plexiform layer using GABA. - An astrocyte of the forebrain. - tberardini - forebrain astrocyte - cell - astrocyte of the forebrain @@ -38875,11 +15422,6 @@ plexiform layer using GABA. - A CNS neuron of the forebrain. - tberardini - forebrain neuron - cell - neuron of the forebrain @@ -38888,7 +15430,6 @@ plexiform layer using GABA. - forebrain radial glial cell @@ -38897,19 +15438,7 @@ plexiform layer using GABA. - Motor neuron that innervate muscles that control eye, jaw, and facial movements of the vertebrate head and parasympathetic neurons that innervate certain glands and organs. - PMID:14699587 - - cranial motoneuron - cranial motor neuron - - - - Motor neuron that innervate muscles that control eye, jaw, and facial movements of the vertebrate head and parasympathetic neurons that innervate certain glands and organs. - ZFIN:CVS - - @@ -38917,7 +15446,6 @@ plexiform layer using GABA. - retrotrapezoid nucleus neuron @@ -38926,7 +15454,6 @@ plexiform layer using GABA. - mesonephric nephron tubule epithelial cell @@ -38935,7 +15462,6 @@ plexiform layer using GABA. - forebrain neuroblast @@ -38944,7 +15470,6 @@ plexiform layer using GABA. - lateral line nerve glial cell @@ -38953,7 +15478,6 @@ plexiform layer using GABA. - spinal cord radial glial cell @@ -38962,8 +15486,6 @@ plexiform layer using GABA. - cell - stretch receptor cell @@ -38972,8 +15494,6 @@ plexiform layer using GABA. - cell - stratified keratinized epithelial stem cell @@ -38982,8 +15502,6 @@ plexiform layer using GABA. - cell - stratified non keratinized epithelial stem cell @@ -38992,7 +15510,6 @@ plexiform layer using GABA. - pronephric nephron tubule epithelial cell @@ -39001,7 +15518,6 @@ plexiform layer using GABA. - metanephric nephron tubule epithelial cell @@ -39012,7 +15528,6 @@ plexiform layer using GABA. - lung goblet cell @@ -39021,7 +15536,6 @@ plexiform layer using GABA. - heart valve cell @@ -39030,23 +15544,7 @@ plexiform layer using GABA. - A specialized epithelial secretory cell that moves chloride ions and water across the tubule epithelium. - FBbt:00005797 - Malpighian tubule Type II cell - Malpighian tubule stellate cell - - - - - A specialized epithelial secretory cell that moves chloride ions and water across the tubule epithelium. - GO:0061330 - - - - - Malpighian tubule Type II cell - FBbt:00005797 - + @@ -39054,7 +15552,6 @@ plexiform layer using GABA. - malpighian tubule tip cell @@ -39063,22 +15560,7 @@ plexiform layer using GABA. - A rod-like cell in the inner ear, having their heads joined and their bases on the basilar membrane widely separated so as to form a spiral tunnel known as the tunnel of Corti. - FMA:75722 - pillar cell of cochlea - pillar cell of corti - rod cell of Corti - cell - cochlear pillar cell - pillar cell - - - - A rod-like cell in the inner ear, having their heads joined and their bases on the basilar membrane widely separated so as to form a spiral tunnel known as the tunnel of Corti. - GOC:tfm - PMID:12417662 - @@ -39086,7 +15568,6 @@ plexiform layer using GABA. - growth plate cartilage chondrocyte @@ -39096,7 +15577,6 @@ plexiform layer using GABA. - stomach neuroendocrine cell @@ -39107,7 +15587,6 @@ plexiform layer using GABA. - lung neuroendocrine cell @@ -39116,7 +15595,6 @@ plexiform layer using GABA. - posterior lateral line nerve glial cell @@ -39125,7 +15603,6 @@ plexiform layer using GABA. - anterior lateral line nerve glial cell @@ -39134,7 +15611,6 @@ plexiform layer using GABA. - posterior lateral line ganglion neuron @@ -39143,7 +15619,6 @@ plexiform layer using GABA. - lung ciliated cell @@ -39152,7 +15627,6 @@ plexiform layer using GABA. - lung secretory cell @@ -39161,9 +15635,6 @@ plexiform layer using GABA. - trophectoderm cell - cell - trophectodermal cell @@ -39172,24 +15643,7 @@ plexiform layer using GABA. - A smooth muscle cell that is part of the small intestine. - FMA:15050 - non-striated muscle fiber of small intestine - cell - smooth muscle cell of small intestine - - - - - A smooth muscle cell that is part of the small intestine. - GOC:tfm - - - - - non-striated muscle fiber of small intestine - FMA:15050 - + @@ -39197,24 +15651,7 @@ plexiform layer using GABA. - A smooth muscle cell that is part of the duodenum. - FMA:15058 - non-striated muscle fiber of duodenum - cell - smooth muscle fiber of duodenum - - - - - A smooth muscle cell that is part of the duodenum. - GOC:tfm - - - - - non-striated muscle fiber of duodenum - FMA:15058 - + @@ -39222,24 +15659,7 @@ plexiform layer using GABA. - A smooth muscle cell that is part of the jejunum. - FMA:15062 - non-striated muscle fiber of jejunum - cell - smooth muscle fiber of jejunum - - - - - A smooth muscle cell that is part of the jejunum. - GOC:tfm - - - - - non-striated muscle fiber of jejunum - FMA:15062 - + @@ -39247,24 +15667,7 @@ plexiform layer using GABA. - A smooth muscle cell that is part of the ileum. - FMA:15066 - non-striated muscle fiber of ileum - cell - smooth muscle fiber of ileum - - - - - A smooth muscle cell that is part of the ileum. - GOC:tfm - - - - - non-striated muscle fiber of ileum - FMA:15066 - + @@ -39272,24 +15675,7 @@ plexiform layer using GABA. - A smooth muscle cell that is part of the large intestine. - FMA:15653 - non-striated muscle fiber of large intestine - cell - smooth muscle cell of large intestine - - - - - A smooth muscle cell that is part of the large intestine. - GOC:tfm - - - - - non-striated muscle fiber of large intestine - FMA:15653 - + @@ -39297,24 +15683,7 @@ plexiform layer using GABA. - A smooth muscle cell that is part of the colon. - FMA:15663 - non-striated muscle fiber of colon - cell - smooth muscle cell of colon - - - - - A smooth muscle cell that is part of the colon. - GOC:tfm - - - - - non-striated muscle fiber of colon - FMA:15663 - + @@ -39322,25 +15691,7 @@ plexiform layer using GABA. - A smooth muscle cell that is part of the cecum. - FMA:15681 - non-striated muscle fiber of cecum - smooth muscle fiber of cecum - cell - smooth muscle cell of cecum - - - - - A smooth muscle cell that is part of the cecum. - GOC:tfm - - - - - non-striated muscle fiber of cecum - FMA:15681 - + @@ -39348,24 +15699,7 @@ plexiform layer using GABA. - A smooth muscle cell that is part of the ascending colon. - FMA:17518 - non-striated muscle fiber of ascending colon - cell - smooth muscle fiber of ascending colon - - - - - A smooth muscle cell that is part of the ascending colon. - GOC:tfm - - - - - non-striated muscle fiber of ascending colon - FMA:17518 - + @@ -39373,24 +15707,7 @@ plexiform layer using GABA. - A smooth muscle cell that is part of the transverse colon. - FMA:17519 - non-striated muscle fiber of transverse colon - cell - smooth muscle fiber of transverse colon - - - - - A smooth muscle cell that is part of the transverse colon. - GOC:tfm - - - - - non-striated muscle fiber of transverse colon - FMA:17519 - + @@ -39398,24 +15715,7 @@ plexiform layer using GABA. - A smooth muscle cell that is part of the descending colon. - FMA:17520 - non-striated muscle fiber of descending colon - cell - smooth muscle fiber of descending colon - - - - - A smooth muscle cell that is part of the descending colon. - GOC:tfm - - - - - non-striated muscle fiber of descending colon - FMA:17520 - + @@ -39423,24 +15723,7 @@ plexiform layer using GABA. - A smooth muscle cell that is part of the sigmoid colon. - FMA:17521 - non-striated muscle fiber of sigmoid colon - cell - smooth muscle cell of sigmoid colon - - - - - A smooth muscle cell that is part of the sigmoid colon. - GOC:tfm - - - - - non-striated muscle fiber of sigmoid colon - FMA:17521 - + @@ -39448,25 +15731,7 @@ plexiform layer using GABA. - A smooth muscle cell that is part of the rectum. - FMA:17522 - non-striated muscle fiber of rectum - smooth muscle fiber of rectum - cell - smooth muscle cell of rectum - - - - - A smooth muscle cell that is part of the rectum. - GOC:tfm - - - - - non-striated muscle fiber of rectum - FMA:17522 - + @@ -39474,17 +15739,7 @@ plexiform layer using GABA. - A muscle cell that is part of the anterior internodal tract. - FMA:223276 - cell - myocyte of anterior internodal tract - - - - A muscle cell that is part of the anterior internodal tract. - GOC:tfm - @@ -39492,17 +15747,7 @@ plexiform layer using GABA. - A muscle cell that is part of the atrial branch of anterior internodal tract. - FMA:223277 - cell - myocyte of atrial branch of anterior internodal tract - - - - A muscle cell that is part of the atrial branch of anterior internodal tract. - GOC:tfm - @@ -39510,17 +15755,7 @@ plexiform layer using GABA. - A muscle cell that is part of the atrial septal branch of anterior internodal tract. - FMA:223278 - cell - myocyte of atrial septal branch of anterior internodal tract - - - - A muscle cell that is part of the atrial septal branch of anterior internodal tract. - GOC:tfm - @@ -39528,17 +15763,7 @@ plexiform layer using GABA. - A muscle cell that is part of the middle internodal tract. - FMA:223279 - cell - myocyte of middle internodal tract - - - - A muscle cell that is part of the middle internodal tract. - GOC:tfm - @@ -39546,17 +15771,7 @@ plexiform layer using GABA. - A muscle cell that is part of the posterior internodal tract. - FMA:223280 - cell - myocyte of posterior internodal tract - - - - A muscle cell that is part of the posterior internodal tract. - GOC:tfm - @@ -39566,17 +15781,7 @@ plexiform layer using GABA. - An epithelial cell that is part of the urethra. - FMA:256165 - cell - epithelial cell of urethra - - - - An epithelial cell that is part of the urethra. - GOC:tfm - @@ -39585,24 +15790,7 @@ plexiform layer using GABA. - A mesothelial cell that is part of the dura mater. - FMA:256516 - squamous mesothelial cell of dura mater - cell - mesothelial cell of dura mater - - - - - A mesothelial cell that is part of the dura mater. - GOC:tfm - - - - - squamous mesothelial cell of dura mater - FMA:256516 - + @@ -39610,17 +15798,7 @@ plexiform layer using GABA. - A fibroblast that is part of the connective tissue of prostate. - FMA:261271 - cell - fibroblast of connective tissue of prostate - - - - A fibroblast that is part of the connective tissue of prostate. - GOC:tfm - @@ -39628,17 +15806,7 @@ plexiform layer using GABA. - A fibroblast that is part of the outer membrane of prostatic capsule. - FMA:261273 - cell - fibroblast of outer membrane of prostatic capsule - - - - A fibroblast that is part of the outer membrane of prostatic capsule. - GOC:tfm - @@ -39646,17 +15814,7 @@ plexiform layer using GABA. - A fibroblast that is part of the subepithelial connective tissue of prostatic gland. - FMA:261275 - cell - fibroblast of subepithelial connective tissue of prostatic gland - - - - A fibroblast that is part of the subepithelial connective tissue of prostatic gland. - GOC:tfm - @@ -39664,17 +15822,7 @@ plexiform layer using GABA. - A fibroblast that is part of the papillary layer of dermis. - FMA:261277 - cell - fibroblast of papillary layer of dermis - - - - A fibroblast that is part of the papillary layer of dermis. - GOC:tfm - @@ -39682,17 +15830,7 @@ plexiform layer using GABA. - A fibroblast that is part of the areolar connective tissue. - FMA:261279 - cell - fibroblast of areolar connective tissue - - - - A fibroblast that is part of the areolar connective tissue. - GOC:tfm - @@ -39700,17 +15838,7 @@ plexiform layer using GABA. - A fibroblast that is part of the connective tissue of nonglandular part of prostate. - FMA:261281 - cell - fibroblast of connective tissue of nonglandular part of prostate - - - - A fibroblast that is part of the connective tissue of nonglandular part of prostate. - GOC:tfm - @@ -39718,17 +15846,7 @@ plexiform layer using GABA. - A fibroblast that is part of the connective tissue of glandular part of prostate. - FMA:261283 - cell - fibroblast of connective tissue of glandular part of prostate - - - - A fibroblast that is part of the connective tissue of glandular part of prostate. - GOC:tfm - @@ -39737,17 +15855,7 @@ plexiform layer using GABA. - A fibroblast that is part of the tunica adventitia of artery. - FMA:261285 - cell - fibroblast of tunica adventitia of artery - - - - A fibroblast that is part of the tunica adventitia of artery. - GOC:tfm - @@ -39755,17 +15863,7 @@ plexiform layer using GABA. - A fibroblast that is part of the dense regular elastic tissue. - FMA:261287 - cell - fibroblast of dense regular elastic tissue - - - - A fibroblast that is part of the dense regular elastic tissue. - GOC:tfm - @@ -39774,17 +15872,7 @@ plexiform layer using GABA. - A fibrocyte that is part of the adventitia of ureter. - FMA:261289 - cell - fibrocyte of adventitia of ureter - - - - A fibrocyte that is part of the adventitia of ureter. - GOC:tfm - @@ -39793,31 +15881,7 @@ plexiform layer using GABA. - A fat cell that is part of the epicardial fat. - FMA:261293 - adipocyte of epicardial fat - epicardial fat cell - cell - epicardial adipocyte - - - - - A fat cell that is part of the epicardial fat. - GOC:tfm - - - - - adipocyte of epicardial fat - FMA:261293 - - - - - epicardial fat cell - FMA:261293 - + @@ -39825,31 +15889,7 @@ plexiform layer using GABA. - A fat cell that is part of the epicardial fat of right ventricle. - FMA:261297 - epicardial adipocyte of right ventricle - epicardial fat cell of right ventricle - cell - adipocyte of epicardial fat of right ventricle - - - - - A fat cell that is part of the epicardial fat of right ventricle. - GOC:tfm - - - - - epicardial adipocyte of right ventricle - FMA:261297 - - - - - epicardial fat cell of right ventricle - FMA:261297 - + @@ -39857,31 +15897,7 @@ plexiform layer using GABA. - A fat cell that is part of the epicardial fat of left ventricle. - FMA:261300 - epicardial adipocyte of left ventricle - epicardial fat cell of left ventricle - cell - adipocyte of epicardial fat of left ventricle - - - - - A fat cell that is part of the epicardial fat of left ventricle. - GOC:tfm - - - - - epicardial adipocyte of left ventricle - FMA:261300 - - - - - epicardial fat cell of left ventricle - FMA:261300 - + @@ -39890,24 +15906,7 @@ plexiform layer using GABA. - A goblet cell that is part of the epithelium of bronchus. - FMA:263032 - goblet cell of epithelium of bronchus - cell - bronchial goblet cell - - - - - A goblet cell that is part of the epithelium of bronchus. - GOC:tfm - - - - - goblet cell of epithelium of bronchus - FMA:263032 - + @@ -39916,24 +15915,7 @@ plexiform layer using GABA. - A goblet cell that is part of the epithelium of stomach. - FMA:263035 - goblet cell of epithelium of stomach - cell - gastric goblet cell - - - - - A goblet cell that is part of the epithelium of stomach. - GOC:tfm - - - - - goblet cell of epithelium of stomach - FMA:263035 - + @@ -39942,18 +15924,7 @@ plexiform layer using GABA. - A goblet cell that is part of the epithelium of gastric cardiac gland. - FMA:263038 - goblet cell of epithelium of gastric cardiac gland - cell - gastric cardiac gland goblet cell - - - - A goblet cell that is part of the epithelium of gastric cardiac gland. - GOC:tfm - @@ -39962,37 +15933,13 @@ plexiform layer using GABA. - A goblet cell that is part of the epithelium of principal gastric gland. - FMA:263040 - goblet cell of epithelium of principal gastric gland - cell - principal gastric gland goblet cell - - - - A goblet cell that is part of the epithelium of principal gastric gland. - GOC:tfm - - - OBSOLETE: A goblet cell that is part of the epithelium of small intestine. - CL:1000495 - FMA:263042 - cell - obsolete goblet cell of epithelium of small intestine - true - - - - - OBSOLETE: A goblet cell that is part of the epithelium of small intestine. - GOC:tfm - + @@ -40000,54 +15947,19 @@ plexiform layer using GABA. - A goblet cell that is part of the epithelium of intestinal villus. - FMA:263046 - goblet cell of epithelium of intestinal villus - cell - intestinal villus goblet cell - - - - A goblet cell that is part of the epithelium of intestinal villus. - GOC:tfm - - - A goblet cell that is part of the epithelium of crypt of lieberkuhn of small intestine. - FMA:263050 - cell - obsolete small intestine crypt goblet cell - true - - - - - A goblet cell that is part of the epithelium of crypt of lieberkuhn of small intestine. - GOC:tfm - + - - OBSOLETE: A goblet cell that is part of the epithelium proper of small intestine. - FMA:263052 - cell - obsolete goblet cell of epithelium proper of small intestine - true - - - - - OBSOLETE: A goblet cell that is part of the epithelium proper of small intestine. - GOC:tfm - + @@ -40056,18 +15968,7 @@ plexiform layer using GABA. - A goblet cell that is part of the epithelium of large intestine. - FMA:263054 - goblet cell of epithelium of large intestine - cell - large intestine goblet cell - - - - A goblet cell that is part of the epithelium of large intestine. - GOC:tfm - @@ -40075,17 +15976,7 @@ plexiform layer using GABA. - A goblet cell that is part of the epithelium of crypt of lieberkuhn of large intestine. - FMA:263056 - cell - large intestine crypt goblet cell - - - - A goblet cell that is part of the epithelium of crypt of lieberkuhn of large intestine. - GOC:tfm - @@ -40095,24 +15986,7 @@ plexiform layer using GABA. - A goblet cell that is part of the epithelium of pancreatic duct. - FMA:263058 - goblet cell of epithelium of pancreatic duct - cell - pancreatic goblet cell - - - - - A goblet cell that is part of the epithelium of pancreatic duct. - GOC:tfm - - - - - goblet cell of epithelium of pancreatic duct - FMA:263058 - + @@ -40121,18 +15995,7 @@ plexiform layer using GABA. - A goblet cell that is part of the epithelium of pyloric gland. - FMA:263061 - goblet cell of epithelium of pyloric gland - cell - pylroric gastric gland goblet cell - - - - A goblet cell that is part of the epithelium of pyloric gland. - GOC:tfm - @@ -40141,18 +16004,7 @@ plexiform layer using GABA. - A goblet cell that is part of the epithelium proper of duodenum. - FMA:263063 - goblet cell of epithelium proper of duodenum - cell - duodenal goblet cell - - - - A goblet cell that is part of the epithelium proper of duodenum. - GOC:tfm - @@ -40160,18 +16012,7 @@ plexiform layer using GABA. - A goblet cell that is part of the epithelium proper of jejunum. - FMA:263065 - goblet cell of epithelium proper of jejunum - cell - jejunal goblet cell - - - - A goblet cell that is part of the epithelium proper of jejunum. - GOC:tfm - @@ -40179,18 +16020,7 @@ plexiform layer using GABA. - A goblet cell that is part of the epithelium proper of ileum. - FMA:263067 - goblet cell of epithelium proper of ileum - cell - ileal goblet cell - - - - A goblet cell that is part of the epithelium proper of ileum. - GOC:tfm - @@ -40199,36 +16029,13 @@ plexiform layer using GABA. - A goblet cell that is part of the epithelium proper of appendix. - FMA:263069 - goblet cell of epithelium proper of appendix - cell - appendix goblet cell - - - - A goblet cell that is part of the epithelium proper of appendix. - GOC:tfm - - - OBSOLETE: A goblet cell that is part of the epithelium proper of large intestine. - FMA:263071 - cell - obsolete goblet cell of epithelium proper of large intestine - true - - - - - OBSOLETE: A goblet cell that is part of the epithelium proper of large intestine. - GOC:tfm - + @@ -40237,24 +16044,7 @@ plexiform layer using GABA. - A goblet cell that is part of the epithelium of trachea. - FMA:263075 - goblet cell of epithelium of trachea - cell - tracheal goblet cell - - - - - A goblet cell that is part of the epithelium of trachea. - GOC:tfm - - - - - goblet cell of epithelium of trachea - FMA:263075 - + @@ -40262,17 +16052,7 @@ plexiform layer using GABA. - A serous secreting cell that is part of the epithelium of trachea. - FMA:263078 - cell - serous cell of epithelium of trachea - - - - A serous secreting cell that is part of the epithelium of trachea. - GOC:tfm - @@ -40280,17 +16060,7 @@ plexiform layer using GABA. - A serous secreting cell that is part of the epithelium of bronchus. - FMA:263080 - cell - serous cell of epithelium of bronchus - - - - A serous secreting cell that is part of the epithelium of bronchus. - GOC:tfm - @@ -40298,17 +16068,7 @@ plexiform layer using GABA. - A serous secreting cell that is part of the epithelium of terminal bronchiole. - FMA:263082 - cell - serous cell of epithelium of terminal bronchiole - - - - A serous secreting cell that is part of the epithelium of terminal bronchiole. - GOC:tfm - @@ -40317,17 +16077,7 @@ plexiform layer using GABA. - A serous secreting cell that is part of the epithelium of bronchiole. - FMA:263084 - cell - serous cell of epithelium of lobular bronchiole - - - - A serous secreting cell that is part of the epithelium of bronchiole. - GOC:tfm - @@ -40336,17 +16086,7 @@ plexiform layer using GABA. - An enterocyte that is part of the epithelium of small intestine. - FMA:263086 - cell - enterocyte of epithelium of small intestine - - - - An enterocyte that is part of the epithelium of small intestine. - GOC:tfm - @@ -40354,17 +16094,7 @@ plexiform layer using GABA. - An enterocyte that is part of the epithelium of intestinal villus. - FMA:263088 - cell - enterocyte of epithelium of intestinal villus - - - - An enterocyte that is part of the epithelium of intestinal villus. - GOC:tfm - @@ -40374,17 +16104,7 @@ plexiform layer using GABA. - An enterocyte that is part of the epithelium of duodenal gland. - FMA:263092 - cell - enterocyte of epithelium of duodenal gland - - - - An enterocyte that is part of the epithelium of duodenal gland. - GOC:tfm - @@ -40392,17 +16112,7 @@ plexiform layer using GABA. - An enterocyte that is part of the epithelium of crypt of lieberkuhn of small intestine. - FMA:263094 - cell - enterocyte of epithelium of crypt of Lieberkuhn of small intestine - - - - An enterocyte that is part of the epithelium of crypt of lieberkuhn of small intestine. - GOC:tfm - @@ -40410,17 +16120,7 @@ plexiform layer using GABA. - An enterocyte that is part of the epithelium proper of small intestine. - FMA:263096 - cell - enterocyte of epithelium proper of small intestine - - - - An enterocyte that is part of the epithelium proper of small intestine. - GOC:tfm - @@ -40428,17 +16128,7 @@ plexiform layer using GABA. - An enterocyte that is part of the epithelium proper of duodenum. - FMA:263098 - cell - enterocyte of epithelium proper of duodenum - - - - An enterocyte that is part of the epithelium proper of duodenum. - GOC:tfm - @@ -40446,17 +16136,7 @@ plexiform layer using GABA. - An enterocyte that is part of the epithelium proper of jejunum. - FMA:263100 - cell - enterocyte of epithelium proper of jejunum - - - - An enterocyte that is part of the epithelium proper of jejunum. - GOC:tfm - @@ -40464,17 +16144,7 @@ plexiform layer using GABA. - An enterocyte that is part of the epithelium proper of ileum. - FMA:263102 - cell - enterocyte of epithelium proper of ileum - - - - An enterocyte that is part of the epithelium proper of ileum. - GOC:tfm - @@ -40483,17 +16153,7 @@ plexiform layer using GABA. - A paneth cell that is part of the epithelium of small intestine. - FMA:263104 - cell - paneth cell of epithelium of small intestine - - - - A paneth cell that is part of the epithelium of small intestine. - GOC:tfm - @@ -40501,17 +16161,7 @@ plexiform layer using GABA. - A Paneth cell that is part of the epithelium proper of small intestine. - FMA:263106 - cell - paneth cell of epithelium proper of small intestine - - - - A Paneth cell that is part of the epithelium proper of small intestine. - GOC:tfm - @@ -40519,17 +16169,7 @@ plexiform layer using GABA. - A Paneth cell that is part of the epithelium of crypt of lieberkuhn of small intestine. - FMA:263108 - cell - paneth cell of epithelium of crypt of Lieberkuhn of small intestine - - - - A Paneth cell that is part of the epithelium of crypt of lieberkuhn of small intestine. - GOC:tfm - @@ -40537,20 +16177,7 @@ plexiform layer using GABA. - MERGED DEFINITION: TARGET DEFINITION: A columnar cell of the colon that is part of the epithelium proper of large intestine. SOURCE DEFINITION: An enterocyte that is part of the epithelium proper of large intestine. - CL:1000336 - FMA:263090 - FMA:263112 - enterocyte of epithelium proper of large intestine - cell - vacuolar absorptive cell of epithelium proper of large intestine - - - - MERGED DEFINITION: TARGET DEFINITION: A columnar cell of the colon that is part of the epithelium proper of large intestine. SOURCE DEFINITION: An enterocyte that is part of the epithelium proper of large intestine. - GOC:tfm - @@ -40559,17 +16186,7 @@ plexiform layer using GABA. - A columnar cell of the colon that is part of the colonic epithelium. - FMA:263114 - cell - vacuolar absorptive cell of epithelium of colon - - - - A columnar cell of the colon that is part of the colonic epithelium. - GOC:tfm - @@ -40578,17 +16195,7 @@ plexiform layer using GABA. - A basal cell that is part of the epithelium of trachea. - FMA:263118 - cell - basal cell of epithelium of trachea - - - - A basal cell that is part of the epithelium of trachea. - GOC:tfm - @@ -40598,19 +16205,7 @@ plexiform layer using GABA. - A basal cell found in the bronchus epithelium. - CL:0002331 - FMA:263120 - basal cell of bronchus - cell - basal cell of epithelium of bronchus - - - - A basal cell found in the bronchus epithelium. - GOC:tfm - @@ -40618,17 +16213,7 @@ plexiform layer using GABA. - A basal cell that is part of the epithelium of terminal bronchiole. - FMA:263122 - cell - basal cell of epithelium of terminal bronchiole - - - - A basal cell that is part of the epithelium of terminal bronchiole. - GOC:tfm - @@ -40636,17 +16221,7 @@ plexiform layer using GABA. - A basal cell that is part of the epithelium of respiratory bronchiole. - FMA:263124 - cell - basal cell of epithelium of respiratory bronchiole - - - - A basal cell that is part of the epithelium of respiratory bronchiole. - GOC:tfm - @@ -40655,17 +16230,7 @@ plexiform layer using GABA. - A basal cell that is part of the epithelium of bronchiole. - FMA:263126 - cell - basal cell of epithelium of lobular bronchiole - - - - A basal cell that is part of the epithelium of bronchiole. - GOC:tfm - @@ -40674,17 +16239,7 @@ plexiform layer using GABA. - A M cell that is part of the epithelium of small intestine. - FMA:263128 - cell - microfold cell of epithelium of small intestine - - - - A M cell that is part of the epithelium of small intestine. - GOC:tfm - @@ -40692,17 +16247,7 @@ plexiform layer using GABA. - A M cell that is part of the epithelium of intestinal villus. - FMA:263130 - cell - microfold cell of epithelium of intestinal villus - - - - A M cell that is part of the epithelium of intestinal villus. - GOC:tfm - @@ -40710,17 +16255,7 @@ plexiform layer using GABA. - A M cell that is part of the epithelium proper of small intestine. - FMA:263132 - cell - microfold cell of epithelium proper of small intestine - - - - A M cell that is part of the epithelium proper of small intestine. - GOC:tfm - @@ -40728,17 +16263,7 @@ plexiform layer using GABA. - A M cell that is part of the epithelium proper of duodenum. - FMA:263134 - cell - microfold cell of epithelium proper of duodenum - - - - A M cell that is part of the epithelium proper of duodenum. - GOC:tfm - @@ -40746,17 +16271,7 @@ plexiform layer using GABA. - A M cell that is part of the epithelium proper of jejunum. - FMA:263136 - cell - microfold cell of epithelium proper of jejunum - - - - A M cell that is part of the epithelium proper of jejunum. - GOC:tfm - @@ -40764,17 +16279,7 @@ plexiform layer using GABA. - A M cell that is part of the epithelium proper of ileum. - FMA:263138 - cell - microfold cell of epithelium proper of ileum - - - - A M cell that is part of the epithelium proper of ileum. - GOC:tfm - @@ -40783,17 +16288,7 @@ plexiform layer using GABA. - A M cell that is part of the epithelium proper of appendix. - FMA:263140 - cell - microfold cell of epithelium proper of appendix - - - - A M cell that is part of the epithelium proper of appendix. - GOC:tfm - @@ -40802,17 +16297,7 @@ plexiform layer using GABA. - A M cell that is part of the epithelium proper of large intestine. - FMA:263142 - cell - microfold cell of epithelium proper of large intestine - - - - A M cell that is part of the epithelium proper of large intestine. - GOC:tfm - @@ -40821,17 +16306,7 @@ plexiform layer using GABA. - A transitional myocyte that is part of the interatrial septum. - FMA:263152 - cell - transitional myocyte of interatrial septum - - - - A transitional myocyte that is part of the interatrial septum. - GOC:tfm - @@ -40840,17 +16315,7 @@ plexiform layer using GABA. - A transitional myocyte that is part of the interventricular septum. - FMA:263154 - cell - transitional myocyte of interventricular septum - - - - A transitional myocyte that is part of the interventricular septum. - GOC:tfm - @@ -40858,17 +16323,7 @@ plexiform layer using GABA. - A transitional myocyte that is part of the atrial branch of anterior internodal tract. - FMA:263156 - cell - transitional myocyte of atrial branch of anterior internodal tract - - - - A transitional myocyte that is part of the atrial branch of anterior internodal tract. - GOC:tfm - @@ -40876,17 +16331,7 @@ plexiform layer using GABA. - A transitional myocyte that is part of the anterior internodal tract. - FMA:263158 - cell - transitional myocyte of anterior internodal tract - - - - A transitional myocyte that is part of the anterior internodal tract. - GOC:tfm - @@ -40894,17 +16339,7 @@ plexiform layer using GABA. - A transitional myocyte that is part of the atrial septal branch of anterior internodal tract. - FMA:263160 - cell - transitional myocyte of atrial septal branch of anterior internodal tract - - - - A transitional myocyte that is part of the atrial septal branch of anterior internodal tract. - GOC:tfm - @@ -40912,17 +16347,7 @@ plexiform layer using GABA. - A transitional myocyte that is part of the middle internodal tract. - FMA:263162 - cell - transitional myocyte of middle internodal tract - - - - A transitional myocyte that is part of the middle internodal tract. - GOC:tfm - @@ -40930,17 +16355,7 @@ plexiform layer using GABA. - A transitional myocyte that is part of the posterior internodal tract. - FMA:263164 - cell - transitional myocyte of posterior internodal tract - - - - A transitional myocyte that is part of the posterior internodal tract. - GOC:tfm - @@ -40948,17 +16363,7 @@ plexiform layer using GABA. - A transitional myocyte that is part of the anterior division of left branch of atrioventricular bundle. - FMA:263166 - cell - transitional myocyte of anterior division of left branch of atrioventricular bundle - - - - A transitional myocyte that is part of the anterior division of left branch of atrioventricular bundle. - GOC:tfm - @@ -40966,17 +16371,7 @@ plexiform layer using GABA. - A transitional myocyte that is part of the septal division of left branch of atrioventricular bundle. - FMA:263168 - cell - transitional myocyte of septal division of left branch of atrioventricular bundle - - - - A transitional myocyte that is part of the septal division of left branch of atrioventricular bundle. - GOC:tfm - @@ -40984,17 +16379,7 @@ plexiform layer using GABA. - A transitional myocyte that is part of the left branch of atrioventricular bundle. - FMA:263170 - cell - transitional myocyte of left branch of atrioventricular bundle - - - - A transitional myocyte that is part of the left branch of atrioventricular bundle. - GOC:tfm - @@ -41002,17 +16387,7 @@ plexiform layer using GABA. - A transitional myocyte that is part of the right branch of atrioventricular bundle. - FMA:263172 - cell - transitional myocyte of right branch of atrioventricular bundle - - - - A transitional myocyte that is part of the right branch of atrioventricular bundle. - GOC:tfm - @@ -41020,17 +16395,7 @@ plexiform layer using GABA. - A transitional myocyte that is part of the atrial part of atrioventricular bundle. - FMA:263174 - cell - transitional myocyte of atrial part of atrioventricular bundle - - - - A transitional myocyte that is part of the atrial part of atrioventricular bundle. - GOC:tfm - @@ -41038,17 +16403,7 @@ plexiform layer using GABA. - A transitional myocyte that is part of the ventricular part of atrioventricular bundle. - FMA:263176 - cell - transitional myocyte of ventricular part of atrioventricular bundle - - - - A transitional myocyte that is part of the ventricular part of atrioventricular bundle. - GOC:tfm - @@ -41056,17 +16411,7 @@ plexiform layer using GABA. - A transitional myocyte that is part of the posterior division of left branch of atrioventricular bundle. - FMA:263178 - cell - transitional myocyte of posterior division of left branch of atrioventricular bundle - - - - A transitional myocyte that is part of the posterior division of left branch of atrioventricular bundle. - GOC:tfm - @@ -41076,17 +16421,7 @@ plexiform layer using GABA. - A myocardial endocrine cell that is part of the septal division of left branch of atrioventricular bundle. - FMA:263180 - cell - myocardial endocrine cell of septal division of left branch of atrioventricular bundle - - - - A myocardial endocrine cell that is part of the septal division of left branch of atrioventricular bundle. - GOC:tfm - @@ -41095,17 +16430,7 @@ plexiform layer using GABA. - A Purkinje myocyte that is part of the interventricular septum. - FMA:263182 - cell - Purkinje myocyte of interventricular septum - - - - A Purkinje myocyte that is part of the interventricular septum. - GOC:tfm - @@ -41114,17 +16439,7 @@ plexiform layer using GABA. - A Feyrter cell that is part of the epithelium of trachea. - FMA:263184 - cell - dense-core granulated cell of epithelium of trachea - - - - A Feyrter cell that is part of the epithelium of trachea. - GOC:tfm - @@ -41136,17 +16451,7 @@ plexiform layer using GABA. - A type I vestibular sensory cell that is part of the stato-acoustic epithelium. - FMA:263186 - cell - type 1 vestibular sensory cell of stato-acoustic epithelium - - - - A type I vestibular sensory cell that is part of the stato-acoustic epithelium. - GOC:tfm - @@ -41158,17 +16463,7 @@ plexiform layer using GABA. - A type I vestibular sensory cell that is part of the epithelium of macula of utricle of membranous labyrinth. - FMA:263188 - cell - type 1 vestibular sensory cell of epithelium of macula of utricle of membranous labyrinth - - - - A type I vestibular sensory cell that is part of the epithelium of macula of utricle of membranous labyrinth. - GOC:tfm - @@ -41180,17 +16475,7 @@ plexiform layer using GABA. - A type I vestibular sensory cell that is part of the epithelium of macula of saccule of membranous labyrinth. - FMA:263190 - cell - type 1 vestibular sensory cell of epithelium of macula of saccule of membranous labyrinth - - - - A type I vestibular sensory cell that is part of the epithelium of macula of saccule of membranous labyrinth. - GOC:tfm - @@ -41202,17 +16487,7 @@ plexiform layer using GABA. - A type I vestibular sensory cell that is part of the epithelium of crista of ampulla of semicircular duct of membranous labyrinth. - FMA:263192 - cell - type 1 vestibular sensory cell of epithelium of crista of ampulla of semicircular duct of membranous labyrinth - - - - A type I vestibular sensory cell that is part of the epithelium of crista of ampulla of semicircular duct of membranous labyrinth. - GOC:tfm - @@ -41224,17 +16499,7 @@ plexiform layer using GABA. - A type II vestibular sensory cell that is part of the stato-acoustic epithelium. - FMA:263194 - cell - type 2 vestibular sensory cell of stato-acoustic epithelium - - - - A type II vestibular sensory cell that is part of the stato-acoustic epithelium. - GOC:tfm - @@ -41246,17 +16511,7 @@ plexiform layer using GABA. - A type II vestibular sensory cell that is part of the epithelium of macula of utricle of membranous labyrinth. - FMA:263196 - cell - type 2 vestibular sensory cell of epithelium of macula of utricle of membranous labyrinth - - - - A type II vestibular sensory cell that is part of the epithelium of macula of utricle of membranous labyrinth. - GOC:tfm - @@ -41268,17 +16523,7 @@ plexiform layer using GABA. - A type II vestibular sensory cell that is part of the epithelium of macula of saccule of membranous labyrinth. - FMA:263198 - cell - type 2 vestibular sensory cell of epithelium of macula of saccule of membranous labyrinth - - - - A type II vestibular sensory cell that is part of the epithelium of macula of saccule of membranous labyrinth. - GOC:tfm - @@ -41290,17 +16535,7 @@ plexiform layer using GABA. - A type II vestibular sensory cell that is part of the epithelium of crista of ampulla of semicircular duct of membranous labyrinth. - FMA:263200 - cell - type 2 vestibular sensory cell of epithelium of crista of ampulla of semicircular duct of membranous labyrinth - - - - A type II vestibular sensory cell that is part of the epithelium of crista of ampulla of semicircular duct of membranous labyrinth. - GOC:tfm - @@ -41308,31 +16543,7 @@ plexiform layer using GABA. - A melanocyte that is part of the eyelid. - FMA:59175 - eyelid melanocyte - sebaceous gland of wolff - cell - melanocyte of eyelid - - - - - A melanocyte that is part of the eyelid. - GOC:tfm - - - - - eyelid melanocyte - FMA:59175 - - - - - sebaceous gland of wolff - FMA:59175 - + @@ -41340,17 +16551,7 @@ plexiform layer using GABA. - A myoepithelial cell that is part of the intralobular part of terminal lactiferous duct. - FMA:62158 - cell - myoepithelial cell of intralobular lactiferous duct - - - - A myoepithelial cell that is part of the intralobular part of terminal lactiferous duct. - GOC:tfm - @@ -41359,18 +16560,7 @@ plexiform layer using GABA. - An endothelial cell that is part of the venous sinus of red pulp of spleen. - FMA:62817 - cell - todo - add logical definition to UBERON:0009967 - endothelial cell of venous sinus of red pulp of spleen - - - - An endothelial cell that is part of the venous sinus of red pulp of spleen. - GOC:tfm - @@ -41378,24 +16568,7 @@ plexiform layer using GABA. - An endothelial cell that is part of the hepatic sinusoid. - FMA:62911 - endotheliocyte of hepatic sinusoid - cell - endothelial cell of hepatic sinusoid - - - - - An endothelial cell that is part of the hepatic sinusoid. - GOC:tfm - - - - - endotheliocyte of hepatic sinusoid - FMA:62911 - + @@ -41403,31 +16576,7 @@ plexiform layer using GABA. - An epithelial cell that is part of the appendix. - FMA:63602 - columnar epitheliocyte of appendix - epithelial cell of vermiform appendix - cell - epithelial cell of appendix - - - - - An epithelial cell that is part of the appendix. - GOC:tfm - - - - - columnar epitheliocyte of appendix - FMA:63602 - - - - - epithelial cell of vermiform appendix - FMA:63602 - + @@ -41435,54 +16584,7 @@ plexiform layer using GABA. - A muscle cell that is part of the sinoatrial node. - FMA:67102 - SA nodal myocyte - SA node cardiac muscle cell - myocyte of sinoatrial node - sinoatrial node cell - sinoatrial node myocyte - sinuatrial node myocyte - cell - myocyte of sinoatrial node - - - - - A muscle cell that is part of the sinoatrial node. - FMA:67102 - GOC:tfm - - - - - SA nodal myocyte - FMA:67102 - - - - - SA node cardiac muscle cell - GOC:pr - - - - - myocyte of sinoatrial node - FMA:67102 - - - - - sinoatrial node cell - GOC:pr - - - - - sinuatrial node myocyte - FMA:67102 - + @@ -41491,53 +16593,7 @@ plexiform layer using GABA. - A muscle cell that is part of the atrioventricular node. - FMA:67106 - AV nodal myocyte - AV node cardiac muscle cell - AV node cell - atrioventricular node cell - atrioventricular node myocyte - cell - myocyte of atrioventricular node - - - - - A muscle cell that is part of the atrioventricular node. - FMA:67106 - GOC:tfm - - - - - AV nodal myocyte - FMA:67106 - - - - - AV node cardiac muscle cell - GOC:pr - - - - - AV node cell - GOC:pr - - - - - atrioventricular node cell - GOC:pr - - - - - atrioventricular node myocyte - FMA:67106 - + @@ -41546,17 +16602,7 @@ plexiform layer using GABA. - An endothelial cell that is part of the small intestine Peyer's patch. - FMA:67757 - cell - endothelial cell of Peyer's patch - - - - An endothelial cell that is part of the small intestine Peyer's patch. - GOC:tfm - @@ -41564,18 +16610,7 @@ plexiform layer using GABA. - An endothelial cell that is part of the arteriole. - FMA:67760 - KUPO:0001097 - cell - endothelial cell of arteriole - - - - An endothelial cell that is part of the arteriole. - GOC:tfm - @@ -41583,21 +16618,7 @@ plexiform layer using GABA. - A blood vessel endothelial cell that is part of an arterial endothelium. - CL:0002542 - BTO:0004758 - FMA:67761 - KUPO:0001095 - arterial endothelial cell - cell - endothelial cell of artery - - - - A blood vessel endothelial cell that is part of an arterial endothelium. - GOC:tfm - @@ -41605,17 +16626,7 @@ plexiform layer using GABA. - An endothelial cell that is part of the venule. - FMA:67762 - cell - endothelial cell of venule - - - - An endothelial cell that is part of the venule. - GOC:tfm - @@ -41624,17 +16635,7 @@ plexiform layer using GABA. - An epithelial cell that is part of the gallbladder. - FMA:67780 - cell - epithelial cell of gall bladder - - - - An epithelial cell that is part of the gallbladder. - GOC:tfm - @@ -41643,25 +16644,7 @@ plexiform layer using GABA. - A myoepithelial cell that is part of the mammary gland. - CALOHA:TS-2378 - FMA:67800 - basal cell of lactiferous duct - cell - myoepithelial cell of lactiferous gland - - - - - A myoepithelial cell that is part of the mammary gland. - GOC:tfm - - - - - basal cell of lactiferous duct - FMA:67800 - + @@ -41670,17 +16653,7 @@ plexiform layer using GABA. - A myoepithelial cell that is part of the sweat gland. - FMA:67801 - cell - myoepithelial cell of sweat gland - - - - A myoepithelial cell that is part of the sweat gland. - GOC:tfm - @@ -41688,31 +16661,7 @@ plexiform layer using GABA. - A myoepithelial cell that is part of the mammary gland alveolus. - FMA:67802 - basal cell of alveolus of lactiferous gland - myoepithelial cell of mammary alveolus - cell - myoepithelial cell of lactiferous alveolus - - - - - A myoepithelial cell that is part of the mammary gland alveolus. - GOC:tfm - - - - - basal cell of alveolus of lactiferous gland - FMA:67802 - - - - - myoepithelial cell of mammary alveolus - FMA:67802 - + @@ -41721,17 +16670,7 @@ plexiform layer using GABA. - A myoepithelial cell that is part of the lactiferous duct. - FMA:67803 - cell - myoepithelial cell of lactiferous duct - - - - A myoepithelial cell that is part of the lactiferous duct. - GOC:tfm - @@ -41739,17 +16678,7 @@ plexiform layer using GABA. - A myoepithelial cell that is part of the terminal lactiferous duct. - FMA:67804 - cell - myoepithelial cell of terminal lactiferous duct - - - - A myoepithelial cell that is part of the terminal lactiferous duct. - GOC:tfm - @@ -41757,24 +16686,7 @@ plexiform layer using GABA. - A chromaffin cell that is part of the paraaortic body. - FMA:69328 - chromaffin cell of para-aortic body - cell - chromaffin cell of paraaortic body - - - - - A chromaffin cell that is part of the paraaortic body. - GOC:tfm - - - - - chromaffin cell of para-aortic body - FMA:69328 - + @@ -41782,17 +16694,7 @@ plexiform layer using GABA. - A chromaffin cell that is part of the paraganglion. - FMA:69335 - cell - chromaffin cell of paraganglion - - - - A chromaffin cell that is part of the paraganglion. - GOC:tfm - @@ -41801,24 +16703,7 @@ plexiform layer using GABA. - A chromaffin cell that is part of the adrenal gland. - FMA:69794 - adrenal chromaffin cell - cell - chromaffin cell of adrenal gland - - - - - A chromaffin cell that is part of the adrenal gland. - GOC:tfm - - - - - adrenal chromaffin cell - GO:0061104 - + @@ -41827,19 +16712,7 @@ plexiform layer using GABA. - A chromaffin cell that is part of the adrenal cortex. - FMA:69795 - chromaffin cell of adrenal cortex - cell - Not clear this cell type exists. Can't call it a cortical adrenal cell because of different germ layer origin. - adrenal cortex chromaffin cell - - - - A chromaffin cell that is part of the adrenal cortex. - GOC:tfm - @@ -41847,24 +16720,7 @@ plexiform layer using GABA. - A somatic stem cell that is part of the epidermis. - FMA:70541 - epidermal stem cell - cell - stem cell of epidermis - - - - - A somatic stem cell that is part of the epidermis. - GOC:tfm - - - - - epidermal stem cell - FMA:70541 - + @@ -41873,24 +16729,7 @@ plexiform layer using GABA. - An epithelial cell that is part of the conjunctiva. - FMA:70552 - epithelial cell of conjunctiva - cell - conjunctival epithelial cell - - - - - An epithelial cell that is part of the conjunctiva. - GOC:tfm - - - - - epithelial cell of conjunctiva - FMA:70552 - + @@ -41899,17 +16738,7 @@ plexiform layer using GABA. - An epithelial cell that is part of the lacrimal canaliculus. - FMA:70553 - cell - epithelial cell of lacrimal canaliculus - - - - An epithelial cell that is part of the lacrimal canaliculus. - GOC:tfm - @@ -41918,17 +16747,7 @@ plexiform layer using GABA. - An epithelial cell that is part of the external acoustic meatus. - FMA:70555 - cell - epithelial cell of external acoustic meatus - - - - An epithelial cell that is part of the external acoustic meatus. - GOC:tfm - @@ -41936,17 +16755,7 @@ plexiform layer using GABA. - An epithelial cell that is part of the lacrimal duct. - FMA:70559 - cell - epithelial cell of lacrimal duct - - - - An epithelial cell that is part of the lacrimal duct. - GOC:tfm - @@ -41954,17 +16763,7 @@ plexiform layer using GABA. - An epithelial cell that is part of the lacrimal sac. - FMA:70560 - cell - epithelial cell of lacrimal sac - - - - An epithelial cell that is part of the lacrimal sac. - GOC:tfm - @@ -41972,17 +16771,7 @@ plexiform layer using GABA. - An epithelial cell that is part of the nasolacrimal duct. - FMA:70561 - cell - epithelial cell of nasolacrimal duct - - - - An epithelial cell that is part of the nasolacrimal duct. - GOC:tfm - @@ -41990,17 +16779,7 @@ plexiform layer using GABA. - An epithelial cell that is part of the wall of inferior part of anal canal. - FMA:70562 - cell - epithelial cell of wall of inferior part of anal canal - - - - An epithelial cell that is part of the wall of inferior part of anal canal. - GOC:tfm - @@ -42009,17 +16788,7 @@ plexiform layer using GABA. - An epithelial cell that is part of the viscerocranial mucosa. - FMA:70583 - cell - epithelial cell of viscerocranial mucosa - - - - An epithelial cell that is part of the viscerocranial mucosa. - GOC:tfm - @@ -42028,24 +16797,7 @@ plexiform layer using GABA. - An urothelial cell that is part of the trigone of urinary bladder. - FMA:70598 - epithelial cell of vesical trigone - cell - urothelial cell of trigone of urinary bladder - - - - - An urothelial cell that is part of the trigone of urinary bladder. - GOC:tfm - - - - - epithelial cell of vesical trigone - FMA:70598 - + @@ -42053,24 +16805,7 @@ plexiform layer using GABA. - A smooth muscle cell that is part of the ciliary body. - FMA:70610 - smooth muscle cell of ciliary body - cell - ciliary muscle cell - - - - - A smooth muscle cell that is part of the ciliary body. - GOC:tfm - - - - - smooth muscle cell of ciliary body - FMA:70610 - + @@ -42078,17 +16813,7 @@ plexiform layer using GABA. - A mesothelial cell that is part of the anterior chamber of eyeball. - FMA:70615 - cell - mesothelial cell of anterior chamber of eye - - - - A mesothelial cell that is part of the anterior chamber of eyeball. - GOC:tfm - @@ -42096,17 +16821,7 @@ plexiform layer using GABA. - A myoepithelial cell that is part of the dilatator pupillae. - FMA:70619 - cell - myoepithelial cell of dilator pupillae - - - - A myoepithelial cell that is part of the dilatator pupillae. - GOC:tfm - @@ -42114,24 +16829,7 @@ plexiform layer using GABA. - A basal cell that is part of the epithelium of esophagus. - FMA:70731 - basal cell of esophageal epithelium - cell - epithelial cell of stratum germinativum of esophagus - - - - - A basal cell that is part of the epithelium of esophagus. - GOC:tfm - - - - - basal cell of esophageal epithelium - FMA:70731 - + @@ -42140,17 +16838,7 @@ plexiform layer using GABA. - An epithelial cell that is part of the sweat gland. - FMA:70952 - cell - epithelial cell of sweat gland - - - - An epithelial cell that is part of the sweat gland. - GOC:tfm - @@ -42158,17 +16846,7 @@ plexiform layer using GABA. - An epithelial cell that is part of the nephron. - FMA:70965 - cell - epithelial cell of nephron - - - - An epithelial cell that is part of the nephron. - GOC:tfm - @@ -42176,26 +16854,7 @@ plexiform layer using GABA. - An epithelial cell that is part of the glomerular capsule. - FMA:70966 - KUPO:0001034 - Bowmans capsule epithelial cell - epithelial cell of Bowman's capsule - cell - epithelial cell of glomerular capsule - - - - - An epithelial cell that is part of the glomerular capsule. - GOC:tfm - - - - - epithelial cell of Bowman's capsule - FMA:70966 - + @@ -42203,25 +16862,7 @@ plexiform layer using GABA. - An epithelial cell that is part of the visceral layer of glomerular capsule. - FMA:70967 - glomerular podocyte - cell - consider merging into CL:0000653 - epithelial cell of visceral layer of glomerular capsule - - - - - An epithelial cell that is part of the visceral layer of glomerular capsule. - GOC:tfm - - - - - glomerular podocyte - FMA:70967 - + @@ -42229,26 +16870,7 @@ plexiform layer using GABA. - An epithelial cell that is part of the glomerular parietal epithelium. - CL:1000897 - FMA:70968 - KUPO:0001035 - epithelial cell of parietal layer of glomerular capsule - cell - parietal epithelial cell - - - - - An epithelial cell that is part of the glomerular parietal epithelium. - GOC:tfm - - - - - epithelial cell of parietal layer of glomerular capsule - FMA:70968 - + @@ -42256,17 +16878,7 @@ plexiform layer using GABA. - An epithelial cell that is part of the intermediate tubule. - FMA:70980 - cell - epithelial cell of intermediate tubule - - - - An epithelial cell that is part of the intermediate tubule. - GOC:tfm - @@ -42275,25 +16887,7 @@ plexiform layer using GABA. - An epithelial cell that is part of the collecting duct of renal tubule. - FMA:70982 - KUPO:0001059 - epithelial cell of renal collecting tubule - cell - kidney collecting duct epithelial cell - - - - - An epithelial cell that is part of the collecting duct of renal tubule. - GOC:tfm - - - - - epithelial cell of renal collecting tubule - FMA:70982 - + @@ -42301,17 +16895,7 @@ plexiform layer using GABA. - A mesothelial cell that is part of the parietal peritoneum. - FMA:72142 - cell - mesothelial cell of parietal peritoneum - - - - A mesothelial cell that is part of the parietal peritoneum. - GOC:tfm - @@ -42319,17 +16903,7 @@ plexiform layer using GABA. - A mesothelial cell that is part of the visceral peritoneum. - FMA:72143 - cell - mesothelial cell of visceral peritoneum - - - - A mesothelial cell that is part of the visceral peritoneum. - GOC:tfm - @@ -42337,25 +16911,7 @@ plexiform layer using GABA. - A melanocyte that is part of the skin of body. - CALOHA:TS-2374 - FMA:72144 - skin melanocyte - cell - melanocyte of skin - - - - - A melanocyte that is part of the skin of body. - GOC:tfm - - - - - skin melanocyte - FMA:72144 - + @@ -42364,17 +16920,7 @@ plexiform layer using GABA. - A chromaffin cell that is part of the ovary. - FMA:74319 - cell - chromaffin cell of ovary - - - - A chromaffin cell that is part of the ovary. - GOC:tfm - @@ -42382,17 +16928,7 @@ plexiform layer using GABA. - A chromaffin cell that is part of the right ovary. - FMA:74320 - cell - chromaffin cell of right ovary - - - - A chromaffin cell that is part of the right ovary. - GOC:tfm - @@ -42400,17 +16936,7 @@ plexiform layer using GABA. - A chromaffin cell that is part of the left ovary. - FMA:74321 - cell - chromaffin cell of left ovary - - - - A chromaffin cell that is part of the left ovary. - GOC:tfm - @@ -42418,24 +16944,7 @@ plexiform layer using GABA. - A myoepithelial cell that is part of the acinus of lactiferous gland. - FMA:74469 - basal cell of acinus of lactiferous gland - cell - myoepithelial cell of acinus of lactiferous gland - - - - - A myoepithelial cell that is part of the acinus of lactiferous gland. - GOC:tfm - - - - - basal cell of acinus of lactiferous gland - FMA:74469 - + @@ -42443,17 +16952,7 @@ plexiform layer using GABA. - A myoepithelial cell that is part of the main lactiferous duct. - FMA:74499 - cell - myoepithelial cell of main lactiferous duct - - - - A myoepithelial cell that is part of the main lactiferous duct. - GOC:tfm - @@ -42461,17 +16960,7 @@ plexiform layer using GABA. - A myoepithelial cell that is part of the primary lactiferous duct. - FMA:74500 - cell - myoepithelial cell of primary lactiferous duct - - - - A myoepithelial cell that is part of the primary lactiferous duct. - GOC:tfm - @@ -42479,17 +16968,7 @@ plexiform layer using GABA. - A myoepithelial cell that is part of the secondary lactiferous duct. - FMA:74501 - cell - myoepithelial cell of secondary lactiferous duct - - - - A myoepithelial cell that is part of the secondary lactiferous duct. - GOC:tfm - @@ -42497,17 +16976,7 @@ plexiform layer using GABA. - A myoepithelial cell that is part of the tertiary lactiferous duct. - FMA:74502 - cell - myoepithelial cell of tertiary lactiferous duct - - - - A myoepithelial cell that is part of the tertiary lactiferous duct. - GOC:tfm - @@ -42515,17 +16984,7 @@ plexiform layer using GABA. - A myoepithelial cell that is part of the quarternary lactiferous duct. - FMA:74503 - cell - myoepithelial cell of quarternary lactiferous duct - - - - A myoepithelial cell that is part of the quarternary lactiferous duct. - GOC:tfm - @@ -42533,20 +16992,7 @@ plexiform layer using GABA. - A nodal myocyte that is part of the sinoatrial node. - FMA:83383 - cardiac pacemaker cell of sinuatrial node - pacemaker cell of sinoatrial node - pacemaker cell of sinuatrial node - cell - cardiac pacemaker cell of sinoatrial node - - - - A nodal myocyte that is part of the sinoatrial node. - GOC:tfm - @@ -42555,18 +17001,7 @@ plexiform layer using GABA. - A transitional myocyte that is part of the sinoatrial node. - FMA:83384 - transitinal myocyte of sinuatrial node - cell - transitional myocyte of sinoatrial node - - - - A transitional myocyte that is part of the sinoatrial node. - GOC:tfm - @@ -42575,17 +17010,7 @@ plexiform layer using GABA. - A Purkinje myocyte that is part of the atrioventricular node. - FMA:83386 - cell - Purkinje myocyte of atrioventricular node - - - - A Purkinje myocyte that is part of the atrioventricular node. - GOC:tfm - @@ -42594,17 +17019,7 @@ plexiform layer using GABA. - A transitional myocyte that is part of the internodal tract. - FMA:83387 - cell - transitional myocyte of internodal tract - - - - A transitional myocyte that is part of the internodal tract. - GOC:tfm - @@ -42614,18 +17029,7 @@ plexiform layer using GABA. - A transitional myocyte that is part of the atrioventricular bundle. - FMA:83388 - FMA:83885 - cell - transitional myocyte of atrioventricular bundle - - - - A transitional myocyte that is part of the atrioventricular bundle. - GOC:tfm - @@ -42634,17 +17038,7 @@ plexiform layer using GABA. - A myocardial endocrine cell that is part of the interventricular septum. - FMA:83390 - cell - myocardial endocrine cell of interventricular septum - - - - A myocardial endocrine cell that is part of the interventricular septum. - GOC:tfm - @@ -42653,17 +17047,7 @@ plexiform layer using GABA. - A Purkinje myocyte that is part of the internodal tract. - FMA:83392 - cell - Purkinje myocyte of internodal tract - - - - A Purkinje myocyte that is part of the internodal tract. - GOC:tfm - @@ -42673,17 +17057,7 @@ plexiform layer using GABA. - A Purkinje myocyte that is part of the atrioventricular bundle. - FMA:83393 - cell - Purkinje myocyte of atrioventricular bundle - - - - A Purkinje myocyte that is part of the atrioventricular bundle. - GOC:tfm - @@ -42691,17 +17065,7 @@ plexiform layer using GABA. - A basal cell that is part of the urothelium. - FMA:84150 - cell - basal cell of urothelium - - - - A basal cell that is part of the urothelium. - GOC:tfm - @@ -42709,24 +17073,7 @@ plexiform layer using GABA. - A smooth muscle cell that is part of the prostate gland. - FMA:84583 - smooth muscle fiber of prostate - cell - smooth muscle cell of prostate - - - - - A smooth muscle cell that is part of the prostate gland. - GOC:tfm - - - - - smooth muscle fiber of prostate - FMA:84583 - + @@ -42734,20 +17081,7 @@ plexiform layer using GABA. - An epithelial cell that is part of the bile duct. Cholangiocytes contribute to bile secretion via net release of bicarbonate and water. They are cuboidal epithelium in the small interlobular bile ducts, but become columnar and mucus secreting in larger bile ducts approaching the porta hepatis and the extrahepatic ducts. - FMA:86481 - epithelial cell of bile duct - cell - cholangiocyte - - - - An epithelial cell that is part of the bile duct. Cholangiocytes contribute to bile secretion via net release of bicarbonate and water. They are cuboidal epithelium in the small interlobular bile ducts, but become columnar and mucus secreting in larger bile ducts approaching the porta hepatis and the extrahepatic ducts. - GOC:tfm - PMID:16550043 - PMID:18356246 - @@ -42756,17 +17090,7 @@ plexiform layer using GABA. - A reticular cell that is part of the splenic cord. - FMA:86497 - cell - reticular cell of splenic cord - - - - A reticular cell that is part of the splenic cord. - GOC:tfm - @@ -42774,24 +17098,7 @@ plexiform layer using GABA. - A mesothelial cell that is part of the peritoneum. - FMA:86736 - peritoneal mesothelial cell - cell - mesothelial cell of peritoneum - - - - - A mesothelial cell that is part of the peritoneum. - GOC:tfm - - - - - peritoneal mesothelial cell - FMA:86736 - + @@ -42799,24 +17106,7 @@ plexiform layer using GABA. - A mesothelial cell that is part of the pleura. - FMA:86737 - pleural mesothelial cell - cell - mesothelial cell of pleura - - - - - A mesothelial cell that is part of the pleura. - GOC:tfm - - - - - pleural mesothelial cell - FMA:86737 - + @@ -42824,17 +17114,7 @@ plexiform layer using GABA. - A mesothelial cell that is part of the parietal pleura. - FMA:86738 - cell - mesothelial cell of parietal pleura - - - - A mesothelial cell that is part of the parietal pleura. - GOC:tfm - @@ -42843,17 +17123,7 @@ plexiform layer using GABA. - A mesothelial cell that is part of the visceral pleura. - FMA:86739 - cell - mesothelial cell of visceral pleura - - - - A mesothelial cell that is part of the visceral pleura. - GOC:tfm - @@ -42861,20 +17131,7 @@ plexiform layer using GABA. - An epithelial cell that is part of a nephron tubule. - FMA:86785 - KUPO:0001022 - kidney tubule epithelial cell - cell - This needs to be further defined as a juxtamedullary nephron. Will request the juxtamedullary nephron tubule class from UBERON. - nephron tubule epithelial cell - - - - An epithelial cell that is part of a nephron tubule. - GOC:tfm - @@ -42883,26 +17140,7 @@ plexiform layer using GABA. - A goblet cell that is part of the small intestine. - FMA:86929 - goblet cell of epithelium of small intestine - goblet cell of small intestine - small intestinal goblet cell - cell - small intestine goblet cell - - - - - A goblet cell that is part of the small intestine. - GOC:tfm - - - - - small intestinal goblet cell - FMA:86929 - + @@ -42911,9 +17149,6 @@ plexiform layer using GABA. - KUPO:0001010 - cell - kidney cell @@ -42922,9 +17157,6 @@ plexiform layer using GABA. - KUPO:0001013 - cell - kidney interstitial cell @@ -42933,9 +17165,6 @@ plexiform layer using GABA. - KUPO:0001017 - cell - kidney medulla cell @@ -42944,10 +17173,6 @@ plexiform layer using GABA. - - KUPO:0001018 - cell - kidney pelvis cell @@ -42956,9 +17181,6 @@ plexiform layer using GABA. - KUPO:0001020 - cell - kidney tubule cell @@ -42967,9 +17189,6 @@ plexiform layer using GABA. - KUPO:0001023 - cell - kidney glomerular epithelial cell @@ -42979,9 +17198,6 @@ plexiform layer using GABA. - KUPO:0001060 - cell - kidney medulla collecting duct epithelial cell @@ -42991,9 +17207,6 @@ plexiform layer using GABA. - KUPO:0001061 - cell - kidney inner medulla collecting duct epithelial cell @@ -43003,9 +17216,6 @@ plexiform layer using GABA. - KUPO:0001062 - cell - kidney outer medulla collecting duct epithelial cell @@ -43015,9 +17225,6 @@ plexiform layer using GABA. - KUPO:0001063 - cell - kidney cortex collecting duct epithelial cell @@ -43026,9 +17233,6 @@ plexiform layer using GABA. - KUPO:0001064 - cell - kidney papillary duct principal epithelial cell @@ -43037,9 +17241,6 @@ plexiform layer using GABA. - KUPO:0001111 - cell - inner renal cortex cell @@ -43049,9 +17250,6 @@ plexiform layer using GABA. - KUPO:0001112 - cell - papillary tips cell @@ -43060,9 +17258,6 @@ plexiform layer using GABA. - KUPO:0001115 - cell - lower urinary tract cell @@ -43071,9 +17266,6 @@ plexiform layer using GABA. - KUPO:0001116 - cell - ureteral cell @@ -43083,9 +17275,6 @@ plexiform layer using GABA. - KUPO:0001015 - cell - kidney nerve cell @@ -43095,9 +17284,6 @@ plexiform layer using GABA. - KUPO:0001021 - cell - kidney corpuscule cell @@ -43107,9 +17293,6 @@ plexiform layer using GABA. - KUPO:0001024 - cell - kidney cortex tubule cell @@ -43118,9 +17301,6 @@ plexiform layer using GABA. - KUPO:0001025 - cell - kidney outer medulla cell @@ -43129,9 +17309,6 @@ plexiform layer using GABA. - KUPO:0001026 - cell - kidney inner medulla cell @@ -43140,17 +17317,7 @@ plexiform layer using GABA. - KUPO:0001028 - juxtaglomerulus cell - cell - juxtaglomerular complex cell - - - - juxtaglomerulus cell - GO:0072052 - @@ -43159,9 +17326,6 @@ plexiform layer using GABA. - KUPO:0001091 - cell - kidney cortex interstitial cell @@ -43171,9 +17335,6 @@ plexiform layer using GABA. - KUPO:0001092 - cell - kidney medulla interstitial cell @@ -43183,9 +17344,6 @@ plexiform layer using GABA. - KUPO:0001101 - cell - kidney interstitial myofibroblast @@ -43195,9 +17353,6 @@ plexiform layer using GABA. - KUPO:0001102 - cell - kidney interstitial fibroblast @@ -43207,9 +17362,6 @@ plexiform layer using GABA. - KUPO:0001103 - cell - kidney interstitial fibrocyte @@ -43219,9 +17371,6 @@ plexiform layer using GABA. - KUPO:0001106 - cell - kidney interstitial alternatively activated macrophage @@ -43231,9 +17380,6 @@ plexiform layer using GABA. - KUPO:0001107 - cell - kidney interstitial inflammatory macrophage @@ -43243,9 +17389,6 @@ plexiform layer using GABA. - KUPO:0001108 - cell - kidney interstitial suppressor macrophage @@ -43255,9 +17398,6 @@ plexiform layer using GABA. - KUPO:0001109 - cell - kidney resident macrophage @@ -43267,9 +17407,6 @@ plexiform layer using GABA. - KUPO:0001110 - cell - kidney resident dendritic cell @@ -43277,11 +17414,8 @@ plexiform layer using GABA. + - - KUPO:0001113 - cell - kidney pelvis smooth muscle cell @@ -43289,12 +17423,9 @@ plexiform layer using GABA. + - - KUPO:0001114 - cell - kidney pelvis urothelial cell @@ -43304,9 +17435,6 @@ plexiform layer using GABA. - KUPO:0001117 - cell - ureter urothelial cell @@ -43317,9 +17445,6 @@ plexiform layer using GABA. - KUPO:0001119 - cell - ureter adventitial cell @@ -43329,9 +17454,6 @@ plexiform layer using GABA. - KUPO:0001130 - cell - kidney cortex collecting duct principal cell @@ -43341,9 +17463,6 @@ plexiform layer using GABA. - KUPO:0001131 - cell - kidney cortex collecting duct intercalated cell @@ -43353,9 +17472,6 @@ plexiform layer using GABA. - KUPO:0001132 - cell - kidney outer medulla collecting duct principal cell @@ -43365,9 +17481,6 @@ plexiform layer using GABA. - KUPO:0001133 - cell - kidney outer medulla collecting duct intercalated cell @@ -43377,9 +17490,6 @@ plexiform layer using GABA. - KUPO:0001134 - cell - kidney inner medulla collecting duct principal cell @@ -43389,9 +17499,6 @@ plexiform layer using GABA. - KUPO:0001135 - cell - kidney inner medulla collecting duct intercalated cell @@ -43401,9 +17508,6 @@ plexiform layer using GABA. - KUPO:0001136 - cell - kidney papillary duct intercalated cell @@ -43413,9 +17517,6 @@ plexiform layer using GABA. - KUPO:0001137 - cell - kidney papillary duct principal cell @@ -43427,24 +17528,7 @@ plexiform layer using GABA. - Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. - KUPO:0001032 - intraglomerular mesangial cell - cell - glomerular mesangial cell - - - - - Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. - Wikipedia:Intraglomerular_mesangial_cell - - - - - intraglomerular mesangial cell - CL:cjm - + @@ -43452,9 +17536,6 @@ plexiform layer using GABA. - KUPO:0001036 - cell - glomerular cell @@ -43464,9 +17545,6 @@ plexiform layer using GABA. - KUPO:0001058 - cell - kidney connecting tubule epithelial cell @@ -43476,9 +17554,6 @@ plexiform layer using GABA. - KUPO:0001093 - cell - kidney inner medulla interstitial cell @@ -43488,9 +17563,6 @@ plexiform layer using GABA. - KUPO:0001094 - cell - kidney outer medulla interstitial cell @@ -43499,9 +17571,6 @@ plexiform layer using GABA. - KUPO:0001045 - cell - kidney proximal convoluted tubule epithelial cell @@ -43512,9 +17581,6 @@ plexiform layer using GABA. - KUPO:0001046 - cell - kidney proximal straight tubule epithelial cell @@ -43523,9 +17589,6 @@ plexiform layer using GABA. - KUPO:0001056 - cell - kidney distal convoluted tubule epithelial cell @@ -43535,9 +17598,6 @@ plexiform layer using GABA. - KUPO:0001057 - cell - macula densa epithelial cell @@ -43547,9 +17607,6 @@ plexiform layer using GABA. - KUPO:0001014 - cell - kidney blood vessel cell @@ -43558,9 +17615,6 @@ plexiform layer using GABA. - KUPO:0001029 - cell - kidney arterial blood vessel cell @@ -43570,9 +17624,6 @@ plexiform layer using GABA. - KUPO:0001030 - cell - kidney capillary endothelial cell @@ -43581,9 +17632,6 @@ plexiform layer using GABA. - KUPO:0001031 - cell - kidney venous blood vessel cell @@ -43592,9 +17640,6 @@ plexiform layer using GABA. - KUPO:0001047 - cell - kidney loop of Henle epithelial cell @@ -43604,9 +17649,6 @@ plexiform layer using GABA. - KUPO:0001118 - cell - ureter smooth muscle cell @@ -43618,9 +17660,6 @@ plexiform layer using GABA. - KUPO:0001037 - cell - glomerular capillary endothelial cell @@ -43630,9 +17669,6 @@ plexiform layer using GABA. - KUPO:0001038 - cell - kidney afferent arteriole cell @@ -43642,9 +17678,6 @@ plexiform layer using GABA. - KUPO:0001041 - cell - kidney efferent arteriole cell @@ -43654,9 +17687,6 @@ plexiform layer using GABA. - KUPO:0001048 - cell - kidney loop of Henle ascending limb epithelial cell @@ -43665,9 +17695,6 @@ plexiform layer using GABA. - KUPO:0001053 - cell - kidney loop of Henle descending limb epithelial cell @@ -43676,9 +17703,6 @@ plexiform layer using GABA. - KUPO:0001065 - cell - peritubular capillary endothelial cell @@ -43689,9 +17713,6 @@ plexiform layer using GABA. - KUPO:0001068 - cell - vasa recta cell @@ -43700,9 +17721,6 @@ plexiform layer using GABA. - KUPO:0001077 - cell - kidney cortex artery cell @@ -43711,9 +17729,6 @@ plexiform layer using GABA. - KUPO:0001084 - cell - kidney cortex vein cell @@ -43724,10 +17739,6 @@ plexiform layer using GABA. - KUPO:0001096 - cell - Note that the source of this term is KUPO:0001096 (artery smooth muscle cell), which we believe actually denotes the kidney specific structure. - kidney artery smooth muscle cell @@ -43738,10 +17749,6 @@ plexiform layer using GABA. - KUPO:0001098 - cell - Note that the source of this term is KUPO:0001098 (arteriole smooth muscle cell), which we believe actually denotes the kidney specific structure. - kidney arteriole smooth muscle cell @@ -43752,10 +17759,6 @@ plexiform layer using GABA. - KUPO:0001100 - cell - Note that the source of this term is KUPO:0001068 (venous system smooth muscle cell), which we believe actually denotes the kidney specific structure. - kidney venous system smooth muscle cell @@ -43766,9 +17769,6 @@ plexiform layer using GABA. - KUPO:0001039 - cell - kidney afferent arteriole endothelial cell @@ -43779,9 +17779,6 @@ plexiform layer using GABA. - KUPO:0001040 - cell - kidney afferent arteriole smooth muscle cell @@ -43791,9 +17788,6 @@ plexiform layer using GABA. - KUPO:0001042 - cell - kidney efferent arteriole endothelial cell @@ -43803,9 +17797,6 @@ plexiform layer using GABA. - KUPO:0001043 - cell - kidney efferent arteriole smooth muscle cell @@ -43815,9 +17806,6 @@ plexiform layer using GABA. - KUPO:0001049 - cell - kidney loop of Henle thick ascending limb epithelial cell @@ -43827,9 +17815,6 @@ plexiform layer using GABA. - KUPO:0001050 - cell - kidney loop of Henle thin ascending limb epithelial cell @@ -43839,9 +17824,6 @@ plexiform layer using GABA. - KUPO:0001051 - cell - kidney loop of Henle medullary thick ascending limb epithelial cell @@ -43850,9 +17832,6 @@ plexiform layer using GABA. - KUPO:0001052 - cell - kidney loop of Henle cortical thick ascending limb epithelial cell @@ -43863,9 +17842,6 @@ plexiform layer using GABA. - KUPO:0001054 - cell - kidney loop of Henle thin descending limb epithelial cell @@ -43875,9 +17851,6 @@ plexiform layer using GABA. - KUPO:0001066 - cell - kidney outer medulla peritubular capillary cell @@ -43886,9 +17859,6 @@ plexiform layer using GABA. - KUPO:0001067 - cell - kidney cortex peritubular capillary cell @@ -43898,9 +17868,6 @@ plexiform layer using GABA. - KUPO:0001069 - cell - inner renal medulla vasa recta cell @@ -43910,9 +17877,6 @@ plexiform layer using GABA. - KUPO:0001070 - cell - outer renal medulla vasa recta cell @@ -43921,9 +17885,6 @@ plexiform layer using GABA. - KUPO:0001074 - cell - vasa recta ascending limb cell @@ -43932,9 +17893,6 @@ plexiform layer using GABA. - KUPO:0001078 - cell - arcuate artery cell @@ -43943,9 +17901,6 @@ plexiform layer using GABA. - KUPO:0001081 - cell - interlobular artery cell @@ -43954,9 +17909,6 @@ plexiform layer using GABA. - KUPO:0001085 - cell - arcuate vein cell @@ -43965,9 +17917,6 @@ plexiform layer using GABA. - KUPO:0001088 - cell - interlobular vein cell @@ -43977,9 +17926,6 @@ plexiform layer using GABA. - KUPO:0001075 - cell - inner medulla vasa recta ascending limb cell @@ -43989,9 +17935,6 @@ plexiform layer using GABA. - KUPO:0001076 - cell - outer medulla vasa recta ascending limb cell @@ -44001,9 +17944,6 @@ plexiform layer using GABA. - KUPO:0001079 - cell - arcuate artery endothelial cell @@ -44013,9 +17953,6 @@ plexiform layer using GABA. - KUPO:0001080 - cell - arcuate artery smooth muscle cell @@ -44025,9 +17962,6 @@ plexiform layer using GABA. - KUPO:0001082 - cell - interlobulary artery endothelial cell @@ -44037,9 +17971,6 @@ plexiform layer using GABA. - KUPO:0001083 - cell - interlobulary artery smooth muscle cell @@ -44049,9 +17980,6 @@ plexiform layer using GABA. - KUPO:0001086 - cell - arcuate vein endothelial cell @@ -44061,9 +17989,6 @@ plexiform layer using GABA. - KUPO:0001087 - cell - arcuate vein smooth muscle cell @@ -44073,9 +17998,6 @@ plexiform layer using GABA. - KUPO:0001089 - cell - interlobulary vein endothelial cell @@ -44085,9 +18007,6 @@ plexiform layer using GABA. - KUPO:0001090 - cell - interlobulary vein smooth muscle cell @@ -44096,10 +18015,6 @@ plexiform layer using GABA. - KUPO:0001012 - Wikipedia:Kidney_collecting_duct_cell - cell - kidney collecting duct cell @@ -44108,9 +18023,6 @@ plexiform layer using GABA. - KUPO:0001071 - cell - vasa recta descending limb cell @@ -44120,9 +18032,6 @@ plexiform layer using GABA. - KUPO:0001072 - cell - inner medulla vasa recta descending limb cell @@ -44132,9 +18041,6 @@ plexiform layer using GABA. - KUPO:0001073 - cell - outer medulla vasa recta descending limb cell @@ -44144,9 +18050,6 @@ plexiform layer using GABA. - KUPO:0001104 - cell - renal interstitial pericyte @@ -44155,9 +18058,6 @@ plexiform layer using GABA. - KUPO:0001120 - cell - bladder cell @@ -44166,9 +18066,6 @@ plexiform layer using GABA. - KUPO:0001123 - cell - urethra cell @@ -44178,9 +18075,6 @@ plexiform layer using GABA. - KUPO:0001121 - cell - bladder urothelial cell @@ -44190,9 +18084,6 @@ plexiform layer using GABA. - KUPO:0001124 - cell - urethra urothelial cell @@ -44202,9 +18093,6 @@ plexiform layer using GABA. - KUPO:0001128 - cell - kidney collecting duct principal cell @@ -44214,10 +18102,6 @@ plexiform layer using GABA. - KUPO:0001129 - http://en.wikipedia.org/wiki/Collecting_duct_system#Intercalated_cells - cell - kidney collecting duct intercalated cell @@ -44226,18 +18110,7 @@ plexiform layer using GABA. - An epithelial cell of the exocrine pancreas. - FMA:70986 - exocrine pancreas cell - cell - epithelial cell of exocrine pancreas - - - - An epithelial cell of the exocrine pancreas. - GOC:tfm - @@ -44247,16 +18120,7 @@ plexiform layer using GABA. - A neuron residing in the olfactory bulb that serve to process and refine signals arising from olfactory sensory neurons - cl - olfactory bulb interneuron - - - - A neuron residing in the olfactory bulb that serve to process and refine signals arising from olfactory sensory neurons - PMID:18603310 - @@ -44264,53 +18128,7 @@ plexiform layer using GABA. - the small neuron in the glomerular layer of the olfactory bulb whose dendrites arborize within a glomerulus, where it receives synaptic input from olfactory receptor cell axon terminals, and also engages in dendrodendritic interactions with mitral and tufted cell dendrites; uses both GABA and dopamine as a neurotransmitter - BTO:0003796 - NIFSTD:nifext_122 - glomerular layer cell - olfactory bulb (accessory) glomerular layer cell - olfactory bulb glomerular layer cell - olfactory bulb glomerularal cell - periglomerular cell - cl - periglomerular cell - - - - - the small neuron in the glomerular layer of the olfactory bulb whose dendrites arborize within a glomerulus, where it receives synaptic input from olfactory receptor cell axon terminals, and also engages in dendrodendritic interactions with mitral and tufted cell dendrites; uses both GABA and dopamine as a neurotransmitter - MP:0009943 - - - - - glomerular layer cell - NIFSTD:nifext_122 - - - - - olfactory bulb (accessory) glomerular layer cell - NIFSTD:nifext_122 - - - - - olfactory bulb glomerular layer cell - NIFSTD:nifext_122 - - - - - olfactory bulb glomerularal cell - MP:0009943 - - - - - periglomerular cell - NIFSTD:nifext_122 - + @@ -44318,16 +18136,7 @@ plexiform layer using GABA. - the subcutaneous mechanoreceptors that innervate tylotrich hair follicles - cl - hair-tylotrich neuron - - - - the subcutaneous mechanoreceptors that innervate tylotrich hair follicles - MP:0000977 - @@ -44335,16 +18144,7 @@ plexiform layer using GABA. - the subcutaneous mechanoreceptors that innervate vellus hairs - cl - hair-down neuron - - - - the subcutaneous mechanoreceptors that innervate vellus hairs - MP:0000979 - @@ -44352,23 +18152,7 @@ plexiform layer using GABA. - A sensory neuron of the dorsal root ganglia that senses body position and sends information about how much the muscle is stretched to the spinal cord. - proprioceptive neuron - cl - sensory neuron of dorsal root ganglion - - - - - A sensory neuron of the dorsal root ganglia that senses body position and sends information about how much the muscle is stretched to the spinal cord. - MP:0004297 - - - - - proprioceptive neuron - MP:0004297 - + @@ -44376,31 +18160,7 @@ plexiform layer using GABA. - the inhibitory projection neurons located in the striatum that integrate glutamatergic signals arising from the cerebral cortex and thalamus - BTO:0004778 - striatal medium spiny neuron - cl - medium-sized densely spiny neuron - medium spiny neuron - - - - - the inhibitory projection neurons located in the striatum that integrate glutamatergic signals arising from the cerebral cortex and thalamus - MP:0008462 - - - - - striatal medium spiny neuron - GO:0021773 - - - - - medium-sized densely spiny neuron - BTO:0004778 - + @@ -44408,16 +18168,7 @@ plexiform layer using GABA. - the large glutaminergic nerve cells whose dendrites synapse with axons of the olfactory receptor neurons in the glomerular layer of the olfactory bulb, and whose axons pass centrally in the olfactory tract to the olfactory cortex - cl - mitral cell - - - - the large glutaminergic nerve cells whose dendrites synapse with axons of the olfactory receptor neurons in the glomerular layer of the olfactory bulb, and whose axons pass centrally in the olfactory tract to the olfactory cortex - MP:0009954 - @@ -44425,16 +18176,7 @@ plexiform layer using GABA. - the principal glutaminergic neuron located in the outer third of the external plexiform layer of the olfactory bulb; a single short primary dendrite traverses the outer external plexiform layer and terminates within an olfactory glomerulus in a tuft of branches, where it receives the input from olfactory receptor neuron axon terminals; axons of the tufted cells transfer information to a number of areas in the brain, including the piriform cortex, entorhinal cortex, olfactory tubercle, and amygdala - cl - olfactory bulb tufted cell - - - - the principal glutaminergic neuron located in the outer third of the external plexiform layer of the olfactory bulb; a single short primary dendrite traverses the outer external plexiform layer and terminates within an olfactory glomerulus in a tuft of branches, where it receives the input from olfactory receptor neuron axon terminals; axons of the tufted cells transfer information to a number of areas in the brain, including the piriform cortex, entorhinal cortex, olfactory tubercle, and amygdala - MP:0009955 - @@ -44445,18 +18187,7 @@ plexiform layer using GABA. - the secretory neurons of the paraventricular nucleus that synthesize and secrete vasopressin, corticotropin-releasing factor (CRF) and thyrotropin-releasing hormone (TRH) into blood vessels in the hypothalamo-pituitary portal system - parvocellular neuron - parvocellular neurosecretory neuron - cl - parvocellular neurosecretory cell - - - - the secretory neurons of the paraventricular nucleus that synthesize and secrete vasopressin, corticotropin-releasing factor (CRF) and thyrotropin-releasing hormone (TRH) into blood vessels in the hypothalamo-pituitary portal system - MP:0010125 - @@ -44465,16 +18196,7 @@ plexiform layer using GABA. - the neurons that utilize glycine as a neurotransmitter - cl - glycinergic neuron - - - - the neurons that utilize glycine as a neurotransmitter - MP:0010385 - @@ -44483,16 +18205,7 @@ plexiform layer using GABA. - the various hormone- or neurotransmitter-secreting cells present throughout the mucosa of the intestinal tract - cl - intestinal enteroendocrine cell - - - - the various hormone- or neurotransmitter-secreting cells present throughout the mucosa of the intestinal tract - MP:0010802 - @@ -44501,16 +18214,7 @@ plexiform layer using GABA. - the various hormone- or neurotransmitter-secreting cells present throughout the mucosa of the stomach - cl - stomach enteroendocrine cell - - - - the various hormone- or neurotransmitter-secreting cells present throughout the mucosa of the stomach - MP:0010803 - @@ -44518,16 +18222,7 @@ plexiform layer using GABA. - chemosensitive cells that innervate the vomernasal organ epithelium and are responsible for receiving and transmitting pheromone signals - cl - vomeronasal sensory neuron - - - - chemosensitive cells that innervate the vomernasal organ epithelium and are responsible for receiving and transmitting pheromone signals - MP:0011679 - @@ -44535,16 +18230,7 @@ plexiform layer using GABA. - a respiratory stem cell found at the junction of the terminal (conductive) bronchiole and the respiratory bronchiole, which gives rise to alveolar cell types and Clara cells in response to lung injury. - cl - bronchioalveolar stem cells - - - - a respiratory stem cell found at the junction of the terminal (conductive) bronchiole and the respiratory bronchiole, which gives rise to alveolar cell types and Clara cells in response to lung injury. - MP:0011691 - @@ -44553,10 +18239,6 @@ plexiform layer using GABA. - cl - endothelial cell of lung - pulmonary vessel endothelial cell - lung endothelial cell @@ -44565,17 +18247,7 @@ plexiform layer using GABA. - BTO:0001141 - cl - PAEC cell - pulmonary artery endothelial cell - - - - PAEC cell - BTO:0001141 - @@ -44584,17 +18256,7 @@ plexiform layer using GABA. - An interneuron of the hippocampus. - FMA:84777 - cl - hippocampal interneuron - - - - An interneuron of the hippocampus. - GOC:pr - @@ -44603,33 +18265,7 @@ plexiform layer using GABA. - A pyramidal neuron of the hippocampus. - NIFSTD:sao131261273 - SAO:sao131261273 - hippocampus (CA) pyramidal cell - hippocampus (CA) pyramidal neuron - cl - hippocampal pyramidal neuron - - - - - A pyramidal neuron of the hippocampus. - GOC:pr - PMID:19342486 - - - - - hippocampus (CA) pyramidal cell - NIFSTD:sao131261273 - - - - - hippocampus (CA) pyramidal neuron - NIFSTD:sao131261273 - + @@ -44638,31 +18274,7 @@ plexiform layer using GABA. - Vascular endothelium found in colon blood vessels. - CALOHA:TS-2397 - colon endothelial cells - colonic endothelial cell - colon endothelial cell - - - - - Vascular endothelium found in colon blood vessels. - NPX:PDR - - - - - colon endothelial cells - CALOHA:TS-2397 - - - - - - colonic endothelial cell - CALOHA:TS-2397 - + @@ -44671,23 +18283,7 @@ plexiform layer using GABA. - Cell of the nasopharyngeal epithelium. - CALOHA:TS-2398 - nasopharynx respiratory epithelial cells - nasopharyngeal epithelial cell - - - - - Cell of the nasopharyngeal epithelium. - NPX:PDR - - - - - nasopharynx respiratory epithelial cells - CALOHA:TS-2398 - + @@ -44696,51 +18292,7 @@ plexiform layer using GABA. - Squamous cell of uterine cervix epithelium. - CALOHA:TS-1251 - cervix squamous cell - cervix squamous epithelial cell - cervix, uterine squamous epithelial cells - uterine cervix squamous epithelial cell - uterine cervix squamous epithelial cells - uterine cervix squamous cell - - - - - Squamous cell of uterine cervix epithelium. - NPX:PDR - - - - - cervix squamous cell - CALOHA:TS-1251 - - - - - cervix squamous epithelial cell - CALOHA:TS-1251 - - - - - cervix, uterine squamous epithelial cells - CALOHA:TS-1251 - - - - - uterine cervix squamous epithelial cell - CALOHA:TS-1251 - - - - - uterine cervix squamous epithelial cells - CALOHA:TS-1251 - + @@ -44749,44 +18301,7 @@ plexiform layer using GABA. - Squamous cell of oral epithelium. - CALOHA:TS-1252 - oral cavity mucosa squamous cell - oral cavity mucosa squamous epithelial cell - oral mucosa squamous epithelial cell - oral mucosa squamous epithelial cells - oral mucosa squamous cell - - - - - Squamous cell of oral epithelium. - NPX:PDR - - - - - oral cavity mucosa squamous cell - CALOHA:TS-1252 - - - - - oral cavity mucosa squamous epithelial cell - CALOHA:TS-1252 - - - - - oral mucosa squamous epithelial cell - CALOHA:TS-1252 - - - - - oral mucosa squamous epithelial cells - CALOHA:TS-1252 - + @@ -44795,44 +18310,7 @@ plexiform layer using GABA. - Squamous cell of tonsil epithelium. - CALOHA:TS-1253 - tonsil squamous epithelial cell - tonsil squamous epithelial cells - tonsillar squamous cell - tonsillar squamous epithelial cell - tonsil squamous cell - - - - - Squamous cell of tonsil epithelium. - NPX:PDR - - - - - tonsil squamous epithelial cell - CALOHA:TS-1253 - - - - - tonsil squamous epithelial cells - CALOHA:TS-1253 - - - - - tonsillar squamous cell - CALOHA:TS-1253 - - - - - tonsillar squamous epithelial cell - CALOHA:TS-1253 - + @@ -44840,44 +18318,7 @@ plexiform layer using GABA. - Squamous cell of vaginal epithelium. - CALOHA:TS-1254 - vagina squamous epithelial cell - vagina squamous epithelial cells - vaginal squamous cell - vaginal squamous epithelial cell - vagina squamous cell - - - - - Squamous cell of vaginal epithelium. - NPX:PDR - - - - - vagina squamous epithelial cell - CALOHA:TS-1254 - - - - - vagina squamous epithelial cells - CALOHA:TS-1254 - - - - - vaginal squamous cell - CALOHA:TS-1254 - - - - - vaginal squamous epithelial cell - CALOHA:TS-1254 - + @@ -44885,37 +18326,7 @@ plexiform layer using GABA. - Glial cell of cerebral cortex. - CALOHA:TS-1256 - brain cortex glial cell - cerebral cortex glial cells - cerebrum cortex glial cell - cerebral cortex glial cell - - - - - Glial cell of cerebral cortex. - NPX:PDR - - - - - brain cortex glial cell - CALOHA:TS-1256 - - - - - cerebral cortex glial cells - CALOHA:TS-1256 - - - - - cerebrum cortex glial cell - CALOHA:TS-1256 - + @@ -44923,37 +18334,7 @@ plexiform layer using GABA. - Glial cell of hippocampus. - CALOHA:TS-1257 - hippocampal glial cell - hippocampus glial cells - hippocampus neuroglial cell - hippocampus glial cell - - - - - Glial cell of hippocampus. - NPX:PDR - - - - - hippocampal glial cell - CALOHA:TS-1257 - - - - - hippocampus glial cells - CALOHA:TS-1257 - - - - - hippocampus neuroglial cell - CALOHA:TS-1257 - + @@ -44961,23 +18342,7 @@ plexiform layer using GABA. - Glial cell of lateral ventricle. - CALOHA:TS-1258 - lateral ventricle glial cells - lateral ventricle glial cell - - - - - Glial cell of lateral ventricle. - NPX:PDR - - - - - lateral ventricle glial cells - CALOHA:TS-1258 - + @@ -44985,61 +18350,13 @@ plexiform layer using GABA. - Neuron of lateral ventricle. - CALOHA:TS-1261 - lateral ventricle neural cell - lateral ventricle neuronal cell - lateral ventricle neuronal cells - lateral ventricle neuron - - - - - Neuron of lateral ventricle. - NPX:PDR - - - - - lateral ventricle neural cell - CALOHA:TS-1261 - - - - - lateral ventricle neuronal cell - CALOHA:TS-1261 - - - - - lateral ventricle neuronal cells - CALOHA:TS-1261 - + - - OBSOLETE: Adipocytes found in the subcutaneous adipose tissue of breast. The breast consists of three main components, the skin, the subcutaneous adipose tissue and the functional glandular tissue that comprises both parenchyma and stroma. - CL:0002617 - breast adipocytes - obsolete breast adipocyte - true - - - - - OBSOLETE: Adipocytes found in the subcutaneous adipose tissue of breast. The breast consists of three main components, the skin, the subcutaneous adipose tissue and the functional glandular tissue that comprises both parenchyma and stroma. - HPA:Breast - - - - - breast adipocytes - CALOHA:TS-2377 - + @@ -45048,44 +18365,7 @@ plexiform layer using GABA. - Glandular cell of appendix epithelium. Example: Goblet cells; enterocytes or absorptive cells; enteroendocrine and M cells. - CALOHA:TS-1271 - appendix glandular cells - caecal appendix glandular cell - cecal appendix glandular cell - vermiform appendix glandular cell - appendix glandular cell - - - - - Glandular cell of appendix epithelium. Example: Goblet cells; enterocytes or absorptive cells; enteroendocrine and M cells. - NPX:PDR - - - - - appendix glandular cells - CALOHA:TS-1271 - - - - - caecal appendix glandular cell - CALOHA:TS-1271 - - - - - cecal appendix glandular cell - CALOHA:TS-1271 - - - - - vermiform appendix glandular cell - CALOHA:TS-1271 - + @@ -45095,37 +18375,7 @@ plexiform layer using GABA. - Glandular cell of mammary epithelium. Example: glandular cells of large and intermediate ducts, glandular cells in terminal ducts. - CALOHA:TS-1272 - breast glandular cell - breast glandular cells - mammary glandular cell - mammary gland glandular cell - - - - - Glandular cell of mammary epithelium. Example: glandular cells of large and intermediate ducts, glandular cells in terminal ducts. - NPX:PDR;HPA:HPA - - - - - breast glandular cell - CALOHA:TS-1272 - - - - - breast glandular cells - CALOHA:TS-1272 - - - - - mammary glandular cell - CALOHA:TS-1272 - + @@ -45134,37 +18384,7 @@ plexiform layer using GABA. - Glandular cell of uterine cervix epithelium. - CALOHA:TS-1273 - cervix glandular cell - cervix, uterine glandular cell - cervix, uterine glandular cells - uterine cervix glandular cell - - - - - Glandular cell of uterine cervix epithelium. - NPX:PDR - - - - - cervix glandular cell - CALOHA:TS-1273 - - - - - cervix, uterine glandular cell - CALOHA:TS-1273 - - - - - cervix, uterine glandular cells - CALOHA:TS-1273 - + @@ -45173,23 +18393,7 @@ plexiform layer using GABA. - Glandular cell of colon epithelium. Example: Goblet cells; enterocytes or absorptive cells; enteroendocrine and M cells. - CALOHA:TS-1274 - colon glandular cells - colon glandular cell - - - - - Glandular cell of colon epithelium. Example: Goblet cells; enterocytes or absorptive cells; enteroendocrine and M cells. - NPX:PDR - - - - - colon glandular cells - CALOHA:TS-1274 - + @@ -45197,23 +18401,7 @@ plexiform layer using GABA. - Glandular cell of duodenal epithelium. Example: Enterocytes, Goblet cells, enteroendocrine cells; Paneth cells; M cells; Brunner's gland cell. - CALOHA:TS-1275 - duodenum glandular cells - duodenum glandular cell - - - - - Glandular cell of duodenal epithelium. Example: Enterocytes, Goblet cells, enteroendocrine cells; Paneth cells; M cells; Brunner's gland cell. - NPX:PDR - - - - - duodenum glandular cells - CALOHA:TS-1275 - + @@ -45222,30 +18410,7 @@ plexiform layer using GABA. - Glandular cell of epididymal epithelium. - CALOHA:TS-1276 - epididymal glandular cell - epididymis glandular cells - epididymis glandular cell - - - - - Glandular cell of epididymal epithelium. - NPX:PDR - - - - - epididymal glandular cell - CALOHA:TS-1276 - - - - - epididymis glandular cells - CALOHA:TS-1276 - + @@ -45253,37 +18418,7 @@ plexiform layer using GABA. - Glandular cell of oviduct epithelium. Example: peg cells, ciliated cells. - CALOHA:TS-1277 - fallopian tube glandular cell - fallopian tube glandular cells - uterine tube glandular cell - oviduct glandular cell - - - - - Glandular cell of oviduct epithelium. Example: peg cells, ciliated cells. - NPX:PDR;HPA:HPA - - - - - fallopian tube glandular cell - CALOHA:TS-1277 - - - - - fallopian tube glandular cells - CALOHA:TS-1277 - - - - - uterine tube glandular cell - CALOHA:TS-1277 - + @@ -45292,37 +18427,7 @@ plexiform layer using GABA. - Glandular cell of gall bladder epithelium. - CALOHA:TS-1278 - gall bladder glandular cells - gallbladder glandular cell - gallbladder glandular cells - gall bladder glandular cell - - - - - Glandular cell of gall bladder epithelium. - NPX:PDR - - - - - gall bladder glandular cells - CALOHA:TS-1278 - - - - - gallbladder glandular cell - CALOHA:TS-1278 - - - - - gallbladder glandular cells - CALOHA:TS-1278 - + @@ -45330,30 +18435,7 @@ plexiform layer using GABA. - Glandular cell of parathyroid epithelium. Example: Parathyroid chief cell and parathyroid oxyphil cells. - CALOHA:TS-1279 - parathyroid gland glandular cell - parathyroid gland glandular cells - parathyroid glandular cell - - - - - Glandular cell of parathyroid epithelium. Example: Parathyroid chief cell and parathyroid oxyphil cells. - NPX:PDR;HPA:HPA - - - - - parathyroid gland glandular cell - CALOHA:TS-1279 - - - - - parathyroid gland glandular cells - CALOHA:TS-1279 - + @@ -45361,30 +18443,7 @@ plexiform layer using GABA. - Glandular cell of rectal epithelium. Example: Goblet cell; enterocytes or absorptive cells; enteroendocrine and M cells. - CALOHA:TS-1281 - rectal glandular cell - rectum glandular cells - rectum glandular cell - - - - - Glandular cell of rectal epithelium. Example: Goblet cell; enterocytes or absorptive cells; enteroendocrine and M cells. - NPX:PDR - - - - - rectal glandular cell - CALOHA:TS-1281 - - - - - rectum glandular cells - CALOHA:TS-1281 - + @@ -45394,23 +18453,7 @@ plexiform layer using GABA. - Glandular cell of salivary gland. Example: Serous cells, mucous cells, cuboidal epithelial cells of the intercalated ducts, simple cuboidal epithelium of the striated ducts, epithelial cells of excretory ducts. - CALOHA:TS-1282 - salivary gland glandular cells - salivary gland glandular cell - - - - - Glandular cell of salivary gland. Example: Serous cells, mucous cells, cuboidal epithelial cells of the intercalated ducts, simple cuboidal epithelium of the striated ducts, epithelial cells of excretory ducts. - NPX:PDR;HPA:HPA - - - - - salivary gland glandular cells - CALOHA:TS-1282 - + @@ -45419,23 +18462,7 @@ plexiform layer using GABA. - Glandular cell of seminal vesicle epithelium. - CALOHA:TS-1283 - seminal vesicle glandular cells - seminal vesicle glandular cell - - - - - Glandular cell of seminal vesicle epithelium. - NPX:PDR - - - - - seminal vesicle glandular cells - CALOHA:TS-1283 - + @@ -45444,38 +18471,7 @@ plexiform layer using GABA. - A glandular cell found in the epithelium of the small intestine. Example: Enterocytes, Goblet cells, enteroendocrine cells; Paneth cells; M cells; Somatostatin-secreting Cells (D-cells) . - CALOHA:TS-1286 - FMA:86928 - small bowel glandular cell - small intestinal glandular cell - small intestine glandular cells - small intestine glandular cell - - - - - A glandular cell found in the epithelium of the small intestine. Example: Enterocytes, Goblet cells, enteroendocrine cells; Paneth cells; M cells; Somatostatin-secreting Cells (D-cells) . - NCI_Thesaurus:Small_Intestinal_Glandular_Cell;NPX:PDR - - - - - small bowel glandular cell - CALOHA:TS-1286 - - - - - small intestinal glandular cell - CALOHA:TS-1286 - - - - - small intestine glandular cells - CALOHA:TS-1286 - + @@ -45485,31 +18481,7 @@ plexiform layer using GABA. - Glandular cell of exocrine pancreas epithelium. Example: pancreatic acinar cell, glandular cells in pancreatic canaliculi, glandular cells in pancreatic ducts. - BTO:0000028 - CALOHA:TS-1242 - exocrine pancreas glandular cell - pancreas exocrine glandular cells - pancreas exocrine glandular cell - - - - - Glandular cell of exocrine pancreas epithelium. Example: pancreatic acinar cell, glandular cells in pancreatic canaliculi, glandular cells in pancreatic ducts. - NPX:PDR;HPA:HPA - - - - - exocrine pancreas glandular cell - CALOHA:TS-1242 - - - - - pancreas exocrine glandular cells - CALOHA:TS-1242 - + @@ -45517,37 +18489,7 @@ plexiform layer using GABA. - Hormone secreting cell located in the cortex of adrenal gland. Glandular cells in the adrenal cortex secrete mineralocorticoids, glucocorticoids and androgens. - CALOHA:TS-2177 - adrenal gland glandular cells - adrenal glandular cell - suprarenal gland glandular cell - adrenal gland glandular cell - - - - - Hormone secreting cell located in the cortex of adrenal gland. Glandular cells in the adrenal cortex secrete mineralocorticoids, glucocorticoids and androgens. - NPX:PDR - - - - - adrenal gland glandular cells - CALOHA:TS-2177 - - - - - adrenal glandular cell - CALOHA:TS-2177 - - - - - suprarenal gland glandular cell - CALOHA:TS-2177 - + @@ -45556,30 +18498,7 @@ plexiform layer using GABA. - Endothelial cells forming the walls of the capillaries within the cerebral cortex. - CALOHA:TS-2372 - cerebral cortex endothelial cells - endothelial cells of cerebral cortex - cerebral cortex endothelial cell - - - - - Endothelial cells forming the walls of the capillaries within the cerebral cortex. - NPX:PDR - - - - - cerebral cortex endothelial cells - CALOHA:TS-2372 - - - - - endothelial cells of cerebral cortex - CALOHA:TS-2372 - + @@ -45587,23 +18506,7 @@ plexiform layer using GABA. - Circulating macrophages and tissue macrophages (alveolar macrophages) of lung. - CALOHA:TS-0576 - lung macrophages - lung macrophage - - - - - Circulating macrophages and tissue macrophages (alveolar macrophages) of lung. - NPX:PDR;HPA:HPA - - - - - lung macrophages - CALOHA:TS-0576 - + @@ -45611,16 +18514,7 @@ plexiform layer using GABA. - Keratinocyte from foreskin. - CALOHA:TS-0385 - foreskin keratinocyte - - - - Keratinocyte from foreskin. - NPX:PDR - @@ -45628,16 +18522,7 @@ plexiform layer using GABA. - Chondrocyte forming the hyaline cartilage found in joints. - CALOHA:TS-0056 - articular chondrocyte - - - - Chondrocyte forming the hyaline cartilage found in joints. - NPX:PDR - @@ -45645,17 +18530,7 @@ plexiform layer using GABA. - Fibroblast from foreskin. - CALOHA:TS-0384 - BJ fibroblast - foreskin fibroblast - - - - Fibroblast from foreskin. - NPX:PDR - @@ -45663,16 +18538,7 @@ plexiform layer using GABA. - Fibroblast from muscle organ. - CALOHA:TS-0643 - muscle fibroblast - - - - Fibroblast from muscle organ. - NPX:PDR - @@ -45681,30 +18547,7 @@ plexiform layer using GABA. - Hematopoietic cells resident in the bone marrow. Include: hematopoietic stem cells (lymphoid stem cells and myeloid stem cells) and the precursor cells for thrombocytes, erythrocytes, basophils, neutrophils, eosinophils, monocytes and lymphocytes. - CALOHA:TS-2109 - bone marrow hematopoietic cells - bone marrow poietic cells - bone marrow hematopoietic cell - - - - - Hematopoietic cells resident in the bone marrow. Include: hematopoietic stem cells (lymphoid stem cells and myeloid stem cells) and the precursor cells for thrombocytes, erythrocytes, basophils, neutrophils, eosinophils, monocytes and lymphocytes. - NPX:PDR - - - - - bone marrow hematopoietic cells - CALOHA:TS-2109 - - - - - bone marrow poietic cells - CALOHA:TS-2109 - + @@ -45712,24 +18555,7 @@ plexiform layer using GABA. - Neuron of the cerebellum. - CALOHA:TS-2359 - FMA:84665 - cerebellum neuron - cerebellar neuron - - - - - Neuron of the cerebellum. - NPX:PDR - - - - - cerebellum neuron - CALOHA:TS-2359 - + @@ -45738,20 +18564,7 @@ plexiform layer using GABA. - Any melanocyte that is part of a epidermis. - TermGenie - 2014-02-03T23:03:09Z - cell - CL:2000000 - These cells are found primarily, but not exclusively, in primates including humans - epidermal melanocyte - - - - Any melanocyte that is part of a epidermis. - GOC:TermGenie - @@ -45760,19 +18573,7 @@ plexiform layer using GABA. - A leukocyte with a single non-segmented nucleus in the mature form found in the circulatory pool of blood. - TermGenie - 2014-02-11T17:29:04Z - cell - CL:2000001 - peripheral blood mononuclear cell - - - - A leukocyte with a single non-segmented nucleus in the mature form found in the circulatory pool of blood. - GOC:TermGenie - @@ -45780,39 +18581,15 @@ plexiform layer using GABA. - Any native cell that is part of a decidua. - TermGenie - 2014-02-20T23:06:41Z - cell - CL:2000002 - decidua cell - - - - Any native cell that is part of a decidua. - GOC:TermGenie - - - Any cell that is part of a pituitary gland. - TermGenie - 2014-03-26T22:14:56Z - cell - CL:2000004 - pituitary gland cell + - - - - Any cell that is part of a pituitary gland. - GOC:TermGenie - @@ -45820,19 +18597,7 @@ plexiform layer using GABA. - Any macroglial cell that is part of a brain. - TermGenie - 2014-03-28T21:35:27Z - cell - CL:2000005 - brain macroglial cell - - - - Any macroglial cell that is part of a brain. - GOC:TermGenie - @@ -45840,19 +18605,7 @@ plexiform layer using GABA. - Any germinal center B cell that is part of a tonsil. - TermGenie - 2014-03-28T21:35:33Z - cell - CL:2000006 - tonsil germinal center B cell - - - - Any germinal center B cell that is part of a tonsil. - GOC:TermGenie - @@ -45860,19 +18613,7 @@ plexiform layer using GABA. - Chondrocyte forming the hyaline cartilage found in the knee joint. - TermGenie - 2014-06-04T14:40:11Z - cell - CL:2000007 - articular chondrocyte of knee joint - - - - Chondrocyte forming the hyaline cartilage found in the knee joint. - GOC:TermGenie - @@ -45880,40 +18621,13 @@ plexiform layer using GABA. - Any blood vessel endothelial cell that is part of a microvascular endothelium. - TermGenie - 2014-06-04T15:07:42Z - cell - CL:2000008 - microvascular endothelial cell - - - - Any blood vessel endothelial cell that is part of a microvascular endothelium. - GOC:TermGenie - - - Any blood vessel endothelial cell that is part of a microvascular endothelium. - CL:2000008 - TermGenie - 2014-06-04T15:09:18Z - cell - CL:2000009 - obsolete microvascular endothelium blood vessel endothelial cell - true - - - - - Any blood vessel endothelial cell that is part of a microvascular endothelium. - GOC:TermGenie - + @@ -45921,19 +18635,7 @@ plexiform layer using GABA. - Any blood vessel endothelial cell that is part of a dermis. - TermGenie - 2014-06-04T15:12:06Z - cell - CL:2000010 - dermis blood vessel endothelial cell - - - - Any blood vessel endothelial cell that is part of a dermis. - GOC:TermGenie - @@ -45941,19 +18643,7 @@ plexiform layer using GABA. - Any endothelial cell of lymphatic vessel that is part of a dermis. - TermGenie - 2014-06-04T15:15:08Z - cell - CL:2000011 - dermis lymphatic vessel endothelial cell - - - - Any endothelial cell of lymphatic vessel that is part of a dermis. - GOC:TermGenie - @@ -45961,19 +18651,7 @@ plexiform layer using GABA. - Any skin fibroblast that is part of a pedal digit skin. - TermGenie - 2014-06-04T15:16:44Z - cell - CL:2000012 - fibroblast of pedal digit skin - - - - Any skin fibroblast that is part of a pedal digit skin. - GOC:TermGenie - @@ -45981,19 +18659,7 @@ plexiform layer using GABA. - Any skin fibroblast that is part of a skin of abdomen. - TermGenie - 2014-06-04T15:18:16Z - cell - CL:2000013 - fibroblast of skin of abdomen - - - - Any skin fibroblast that is part of a skin of abdomen. - GOC:TermGenie - @@ -46001,19 +18667,7 @@ plexiform layer using GABA. - Any skin fibroblast that is part of a upper leg skin. - TermGenie - 2014-06-04T15:19:44Z - cell - CL:2000014 - fibroblast of upper leg skin - - - - Any skin fibroblast that is part of a upper leg skin. - GOC:TermGenie - @@ -46021,19 +18675,7 @@ plexiform layer using GABA. - Any skin fibroblast that is part of a arm. - TermGenie - 2014-06-04T15:29:06Z - cell - CL:2000015 - fibroblast of arm - - - - Any skin fibroblast that is part of a arm. - GOC:TermGenie - @@ -46041,19 +18683,7 @@ plexiform layer using GABA. - Any lung endothelial cell that is part of a microvascular endothelium. - TermGenie - 2014-06-04T16:00:56Z - cell - CL:2000016 - lung microvascular endothelial cell - - - - Any lung endothelial cell that is part of a microvascular endothelium. - GOC:TermGenie - @@ -46061,19 +18691,7 @@ plexiform layer using GABA. - Any fibroblast that is part of a periodontal ligament. - TermGenie - 2014-06-04T16:50:33Z - cell - CL:2000017 - fibroblast of peridontal ligament - - - - Any fibroblast that is part of a periodontal ligament. - GOC:TermGenie - @@ -46082,19 +18700,7 @@ plexiform layer using GABA. - Any endothelial cell of artery that is part of a coronary artery. - TermGenie - 2014-06-04T17:08:47Z - cell - CL:2000018 - endothelial cell of coronary artery - - - - Any endothelial cell of artery that is part of a coronary artery. - GOC:TermGenie - @@ -46102,19 +18708,7 @@ plexiform layer using GABA. - Any photoreceptor cell that is part of a compound eye. - TermGenie - 2014-06-24T23:16:45Z - cell - CL:2000019 - compound eye photoreceptor cell - - - - Any photoreceptor cell that is part of a compound eye. - GOC:TermGenie - @@ -46122,19 +18716,7 @@ plexiform layer using GABA. - Any native cell that is part of a inner cell mass. - TermGenie - 2014-06-24T23:16:53Z - cell - CL:2000020 - inner cell mass native cell - - - - Any native cell that is part of a inner cell mass. - GOC:TermGenie - @@ -46142,19 +18724,7 @@ plexiform layer using GABA. - Any native cell that is part of a sebaceous gland. - TermGenie - 2014-06-24T23:17:00Z - cell - CL:2000021 - sebaceous gland native cell - - - - Any native cell that is part of a sebaceous gland. - GOC:TermGenie - @@ -46162,19 +18732,7 @@ plexiform layer using GABA. - Any native cell that is part of a cardiac septum. - TermGenie - 2014-06-24T23:17:07Z - cell - CL:2000022 - cardiac septum native cell - - - - Any native cell that is part of a cardiac septum. - GOC:TermGenie - @@ -46182,19 +18740,7 @@ plexiform layer using GABA. - Any interneuron that is part of a spinal cord ventral column. - TermGenie - 2014-06-25T00:23:36Z - cell - CL:2000023 - spinal cord ventral column interneuron - - - - Any interneuron that is part of a spinal cord ventral column. - GOC:TermGenie - @@ -46202,19 +18748,7 @@ plexiform layer using GABA. - Any neuron that is part of a spinal cord medial motor column. - TermGenie - 2014-06-25T00:23:43Z - cell - CL:2000024 - spinal cord medial motor column neuron - - - - Any neuron that is part of a spinal cord medial motor column. - GOC:TermGenie - @@ -46222,39 +18756,13 @@ plexiform layer using GABA. - Any oligodendrocyte that is part of a spinal cord. - TermGenie - 2014-06-25T00:23:50Z - cell - CL:2000025 - spinal cord oligodendrocyte - - - - Any oligodendrocyte that is part of a spinal cord. - GOC:TermGenie - - - Any Golgi cell that is part of a cerebellum. - TermGenie - 2014-06-25T00:23:57Z - cell - CL:2000026 - obsolete cerebellum Golgi cell - true - - - - - Any Golgi cell that is part of a cerebellum. - GOC:TermGenie - + @@ -46263,19 +18771,7 @@ plexiform layer using GABA. - Any basket cell that is part of a cerebellum. - TermGenie - 2014-06-25T00:24:03Z - cell - CL:2000027 - cerebellum basket cell - - - - Any basket cell that is part of a cerebellum. - GOC:TermGenie - @@ -46284,19 +18780,7 @@ plexiform layer using GABA. - Any glutamatergic neuron that is part of a cerebellum. - TermGenie - 2014-06-25T00:24:10Z - cell - CL:2000028 - cerebellum glutamatergic neuron - - - - Any glutamatergic neuron that is part of a cerebellum. - GOC:TermGenie - @@ -46304,39 +18788,15 @@ plexiform layer using GABA. - Any neuron that is part of a central nervous system. - TermGenie - 2014-06-25T01:17:43Z - cell - CL:2000029 - central nervous system neuron - - - - Any neuron that is part of a central nervous system. - GOC:TermGenie - - - Any native cell that is part of a hypothalamus. - TermGenie - 2014-06-25T01:17:50Z - cell - CL:2000030 - hypothalamus native cell + - - - - Any native cell that is part of a hypothalamus. - GOC:TermGenie - @@ -46344,19 +18804,7 @@ plexiform layer using GABA. - Any neuron that is part of a lateral line ganglion. - TermGenie - 2014-06-25T01:17:57Z - cell - CL:2000031 - lateral line ganglion neuron - - - - Any neuron that is part of a lateral line ganglion. - GOC:TermGenie - @@ -46364,19 +18812,7 @@ plexiform layer using GABA. - Any neuron that is part of a peripheral nervous system. - TermGenie - 2014-06-25T02:28:17Z - cell - CL:2000032 - peripheral nervous system neuron - - - - Any neuron that is part of a peripheral nervous system. - GOC:TermGenie - @@ -46384,19 +18820,7 @@ plexiform layer using GABA. - Any basal cell of epidermis that is part of a limb. - TermGenie - 2014-06-25T02:28:25Z - cell - CL:2000033 - limb basal cell of epidermis - - - - Any basal cell of epidermis that is part of a limb. - GOC:TermGenie - @@ -46404,19 +18828,7 @@ plexiform layer using GABA. - Any neuromast hair cell that is part of a anterior lateral line. - TermGenie - 2014-06-25T03:44:37Z - cell - CL:2000034 - anterior lateral line neuromast hair cell - - - - Any neuromast hair cell that is part of a anterior lateral line. - GOC:TermGenie - @@ -46424,19 +18836,7 @@ plexiform layer using GABA. - Any neuromast mantle cell that is part of a anterior lateral line. - TermGenie - 2014-06-25T03:44:44Z - cell - CL:2000035 - anterior lateral line neuromast mantle cell - - - - Any neuromast mantle cell that is part of a anterior lateral line. - GOC:TermGenie - @@ -46444,19 +18844,7 @@ plexiform layer using GABA. - Any neuromast support cell that is part of a anterior lateral line. - TermGenie - 2014-06-25T03:44:51Z - cell - CL:2000036 - anterior lateral line neuromast support cell - - - - Any neuromast support cell that is part of a anterior lateral line. - GOC:TermGenie - @@ -46464,19 +18852,7 @@ plexiform layer using GABA. - Any neuromast hair cell that is part of a posterior lateral line. - TermGenie - 2014-06-25T03:44:57Z - cell - CL:2000037 - posterior lateral line neuromast hair cell - - - - Any neuromast hair cell that is part of a posterior lateral line. - GOC:TermGenie - @@ -46484,19 +18860,7 @@ plexiform layer using GABA. - Any neuromast mantle cell that is part of a posterior lateral line. - TermGenie - 2014-06-25T03:45:04Z - cell - CL:2000038 - posterior lateral line neuromast mantle cell - - - - Any neuromast mantle cell that is part of a posterior lateral line. - GOC:TermGenie - @@ -46504,19 +18868,7 @@ plexiform layer using GABA. - Any neuromast support cell that is part of a posterior lateral line. - TermGenie - 2014-06-25T03:45:11Z - cell - CL:2000039 - posterior lateral line neuromast support cell - - - - Any neuromast support cell that is part of a posterior lateral line. - GOC:TermGenie - @@ -46525,19 +18877,7 @@ plexiform layer using GABA. - Any microvascular endothelial cell that is part of a urinary bladder. - TermGenie - 2014-07-09T00:04:47Z - cell - CL:2000040 - bladder microvascular endothelial cell - - - - Any microvascular endothelial cell that is part of a urinary bladder. - GOC:TermGenie - @@ -46545,19 +18885,7 @@ plexiform layer using GABA. - Any dermis lymphatic vessel endothelial cell that is part of a microvascular endothelium. - TermGenie - 2014-07-09T00:09:54Z - cell - CL:2000041 - dermis microvascular lymphatic vessel endothelial cell - - - - Any dermis lymphatic vessel endothelial cell that is part of a microvascular endothelium. - GOC:TermGenie - @@ -46565,19 +18893,7 @@ plexiform layer using GABA. - Any fibroblast that is part of a embryo. - TermGenie - 2014-07-09T00:12:00Z - cell - CL:2000042 - embryonic fibroblast - - - - Any fibroblast that is part of a embryo. - GOC:TermGenie - @@ -46585,19 +18901,7 @@ plexiform layer using GABA. - Any pericyte cell that is part of a brain. - TermGenie - 2014-07-09T00:18:22Z - cell - CL:2000043 - brain pericyte - - - - Any pericyte cell that is part of a brain. - GOC:TermGenie - @@ -46606,19 +18910,7 @@ plexiform layer using GABA. - Any microvascular endothelial cell that is part of a brain. - TermGenie - 2014-07-09T00:24:53Z - cell - CL:2000044 - brain microvascular endothelial cell - - - - Any microvascular endothelial cell that is part of a brain. - GOC:TermGenie - @@ -46626,19 +18918,7 @@ plexiform layer using GABA. - Any melanocyte that is part of a prepuce of penis. - TermGenie - 2014-07-09T00:45:07Z - cell - CL:2000045 - foreskin melanocyte - - - - Any melanocyte that is part of a prepuce of penis. - GOC:TermGenie - @@ -46646,19 +18926,7 @@ plexiform layer using GABA. - Any cardiac muscle cell that is part of a cardiac ventricle. - TermGenie - 2014-08-12T20:50:28Z - cell - CL:2000046 - ventricular cardiac muscle cell - - - - Any cardiac muscle cell that is part of a cardiac ventricle. - GOC:TermGenie - @@ -46667,19 +18935,7 @@ plexiform layer using GABA. - Any motor neuron that is part of a brainstem. - TermGenie - 2014-10-02T23:52:53Z - cell - CL:2000047 - brainstem motor neuron - - - - Any motor neuron that is part of a brainstem. - GOC:TermGenie - @@ -46687,19 +18943,7 @@ plexiform layer using GABA. - Any spinal cord motor neuron that is part of a ventral horn of spinal cord. - TermGenie - 2014-10-03T00:26:27Z - cell - CL:2000048 - ventral horn of spinal cord spinal cord motor neuron - - - - Any spinal cord motor neuron that is part of a ventral horn of spinal cord. - GOC:TermGenie - @@ -46707,41 +18951,13 @@ plexiform layer using GABA. - Any pyramidal cell that is part of a primary motor cortex. - TermGenie - 2014-10-06T17:39:04Z - cell - CL:2000049 - http://www.ncbi.nlm.nih.gov/pubmed/12524689 - primary motor cortex pyramidal cell - - - - Any pyramidal cell that is part of a primary motor cortex. - GOC:TermGenie - - - Any retinal ganglion cell that is part of a retina. - TermGenie - 2014-10-06T17:43:59Z - cell - CL:2000050 - http://www.ncbi.nlm.nih.gov/pubmed/2889210 - obsolete retina retinal ganglion cell - true - - - - - Any retinal ganglion cell that is part of a retina. - GOC:TermGenie - + @@ -46749,19 +18965,7 @@ plexiform layer using GABA. - Any fibroblast that is part of a spleen. - TermGenie - 2014-10-06T18:58:47Z - cell - CL:2000051 - splenic fibroblast - - - - Any fibroblast that is part of a spleen. - GOC:TermGenie - @@ -46770,20 +18974,7 @@ plexiform layer using GABA. - Any endothelial cell of artery that is part of a umbilical cord. - TermGenie - 2014-10-06T19:01:48Z - cell - CL:2000052 - http://www.sciencellonline.com/site/productInformation.php?keyword=8010 - umbilical artery endothelial cell - - - - Any endothelial cell of artery that is part of a umbilical cord. - GOC:TermGenie - @@ -46791,20 +18982,7 @@ plexiform layer using GABA. - Any endothelial cell that is part of a spleen. - TermGenie - 2014-10-06T19:06:04Z - cell - CL:2000053 - http://www.sciencellonline.com/site/productInformation.php?keyword=5500 - splenic endothelial cell - - - - Any endothelial cell that is part of a spleen. - GOC:TermGenie - @@ -46812,20 +18990,7 @@ plexiform layer using GABA. - A large, granular, liver specific natural killer cell that adheres to the endothelial cells of the hepatic sinusoid. - 2014-10-06T19:08:51Z - cell - CL:2000054 - Pit cells are named for the presence of large cytoplasmic granules that resemble pits (pips) of fruit. - hepatic pit cell - - - - A large, granular, liver specific natural killer cell that adheres to the endothelial cells of the hepatic sinusoid. - GOC:dos - PMID:9408963 - @@ -46833,20 +18998,7 @@ plexiform layer using GABA. - Any dendritic cell that is part of a liver. - TermGenie - 2014-10-06T19:16:11Z - cell - CL:2000055 - http://www.jleukbio.org/content/66/2/322.abstract - liver dendritic cell - - - - Any dendritic cell that is part of a liver. - GOC:TermGenie - @@ -46855,19 +19007,7 @@ plexiform layer using GABA. - Any pyramidal cell that is part of a regional part of cerebral cortex. - TermGenie - 2014-10-06T19:20:41Z - cell - CL:2000056 - Meynert cell - - - - Any pyramidal cell that is part of a regional part of cerebral cortex. - GOC:TermGenie - @@ -46876,20 +19016,7 @@ plexiform layer using GABA. - Any osteoblast that is part of a femur. - TermGenie - 2014-10-06T19:29:45Z - cell - CL:2000057 - http://www.sciencellonline.com/site/productInformation.php?keyword=4610 - femural osteoblast - - - - Any osteoblast that is part of a femur. - GOC:TermGenie - @@ -46897,20 +19024,7 @@ plexiform layer using GABA. - Any osteoblast that is part of a skull. - TermGenie - 2014-10-06T19:48:30Z - cell - CL:2000058 - http://www.sciencellonline.com/site/productInformation.php?keyword=4600 - calvarial osteoblast - - - - Any osteoblast that is part of a skull. - GOC:TermGenie - @@ -46918,20 +19032,7 @@ plexiform layer using GABA. - Any microvascular endothelial cell that is part of a prostate gland. - TermGenie - 2014-10-07T17:46:27Z - cell - CL:2000059 - http://www.sciencellonline.com/site/productInformation.php?keyword=4400 - prostate gland microvascular endothelial cell - - - - Any microvascular endothelial cell that is part of a prostate gland. - GOC:TermGenie - @@ -46939,20 +19040,7 @@ plexiform layer using GABA. - Any trophoblast cell that is part of a placenta. - TermGenie - 2014-10-07T17:48:27Z - cell - CL:2000060 - http://www.sciencellonline.com/site/productInformation.php?keyword=7120 - placental villous trophoblast - - - - Any trophoblast cell that is part of a placenta. - GOC:TermGenie - @@ -46960,20 +19048,7 @@ plexiform layer using GABA. - Any mesenchymal stem cell that is part of a placenta. - TermGenie - 2014-10-07T17:51:11Z - cell - CL:2000061 - http://www.sciencellonline.com/site/productInformation.php?keyword=7140 - placental amniotic mesenchymal stromal cell - - - - Any mesenchymal stem cell that is part of a placenta. - GOC:TermGenie - @@ -46982,20 +19057,7 @@ plexiform layer using GABA. - Any capillary endothelial cell that is part of a placenta. - TermGenie - 2014-10-07T17:55:56Z - cell - CL:2000062 - http://www.ncbi.nlm.nih.gov/books/NBK53245/ - placental villus capillary endothelial cell - - - - Any capillary endothelial cell that is part of a placenta. - GOC:TermGenie - @@ -47003,20 +19065,7 @@ plexiform layer using GABA. - Any fibroblast that is part of a female gonad. - TermGenie - 2014-10-07T17:57:42Z - cell - CL:2000063 - http://www.sciencellonline.com/site/productInformation.php?keyword=7330 - ovarian fibroblast - - - - Any fibroblast that is part of a female gonad. - GOC:TermGenie - @@ -47024,20 +19073,7 @@ plexiform layer using GABA. - Any epithelial cell that is part of a female gonad. - TermGenie - 2014-10-07T17:59:13Z - cell - CL:2000064 - http://www.sciencellonline.com/site/productInformation.php?keyword=7310 - ovarian surface epithelial cell - - - - Any epithelial cell that is part of a female gonad. - GOC:TermGenie - @@ -47046,20 +19082,7 @@ plexiform layer using GABA. - Any microvascular endothelial cell that is part of a female urethra. - TermGenie - 2014-10-07T18:18:01Z - cell - CL:2000065 - http://www.sciencellonline.com/site/productInformation.php?keyword=7300 - ovarian microvascular endothelial cell - - - - Any microvascular endothelial cell that is part of a female urethra. - GOC:TermGenie - @@ -47067,20 +19090,7 @@ plexiform layer using GABA. - Any fibroblast that is part of a cardiac ventricle. - TermGenie - 2014-10-07T18:35:38Z - cell - CL:2000066 - http://www.sciencellonline.com/site/productInformation.php?keyword=6310 - cardiac ventricle fibroblast - - - - Any fibroblast that is part of a cardiac ventricle. - GOC:TermGenie - @@ -47088,20 +19098,7 @@ plexiform layer using GABA. - Any fibroblast that is part of a cardiac atrium. - TermGenie - 2014-10-07T18:36:54Z - cell - CL:2000067 - http://www.sciencellonline.com/site/productInformation.php?keyword=6320 - cardiac atrium fibroblast - - - - Any fibroblast that is part of a cardiac atrium. - GOC:TermGenie - @@ -47109,20 +19106,7 @@ plexiform layer using GABA. - Any fibroblast that is part of a pericardium. - TermGenie - 2014-10-07T18:38:06Z - cell - CL:2000068 - http://www.sciencellonline.com/site/productInformation.php?keyword=6430 - pericardium fibroblast - - - - Any fibroblast that is part of a pericardium. - GOC:TermGenie - @@ -47130,20 +19114,7 @@ plexiform layer using GABA. - Any fibroblast that is part of a gallbladder. - TermGenie - 2014-10-07T18:41:43Z - cell - CL:2000069 - http://www.sciencellonline.com/site/productInformation.php?keyword=5430 - gallbladder fibroblast - - - - Any fibroblast that is part of a gallbladder. - GOC:TermGenie - @@ -47151,20 +19122,7 @@ plexiform layer using GABA. - Any fibroblast that is part of a optic choroid. - TermGenie - 2014-10-07T18:50:43Z - cell - CL:2000070 - http://www.sciencellonline.com/site/productInformation.php?keyword=6620 - optic choroid fibroblast - - - - Any fibroblast that is part of a optic choroid. - GOC:TermGenie - @@ -47172,20 +19130,7 @@ plexiform layer using GABA. - Any microvascular endothelial cell that is part of a breast. - TermGenie - 2014-10-07T19:55:30Z - cell - CL:2000071 - http://www.sciencellonline.com/site/productInformation.php?keyword=7600 - mammary microvascular endothelial cell - - - - Any microvascular endothelial cell that is part of a breast. - GOC:TermGenie - @@ -47194,20 +19139,7 @@ plexiform layer using GABA. - Any microvascular endothelial cell that is part of a adipose tissue. - TermGenie - 2014-10-07T22:13:45Z - cell - CL:2000072 - http://www.sciencellonline.com/site/productInformation.php?keyword=7200 - adipose microvascular endothelial cell - - - - Any microvascular endothelial cell that is part of a adipose tissue. - GOC:TermGenie - @@ -47215,19 +19147,7 @@ plexiform layer using GABA. - Any migratory neural crest cell that is part of a cardiac neural crest. - TermGenie - 2014-11-05T01:18:43Z - cell - CL:2000073 - migratory cardiac neural crest cell - - - - Any migratory neural crest cell that is part of a cardiac neural crest. - GOC:TermGenie - @@ -47235,20 +19155,7 @@ plexiform layer using GABA. - Any leukocyte that is part of a spleen. - TermGenie - 2014-11-05T01:26:50Z - cell - CL:2000074 - Splenocytes is a vague term that refers to any one of the different white blood cell types in the spleen. This name is seen many references as such and is not explained further, necessitating a need for this terminology. - splenocyte - - - - Any leukocyte that is part of a spleen. - GOC:TermGenie - @@ -47256,19 +19163,7 @@ plexiform layer using GABA. - Any endodermal cell that is part of a anterior visceral endoderm. - TermGenie - 2014-11-05T01:34:13Z - cell - CL:2000075 - anterior visceral endoderm cell - - - - Any endodermal cell that is part of a anterior visceral endoderm. - GOC:TermGenie - @@ -47276,19 +19171,7 @@ plexiform layer using GABA. - Any vein endothelial cell that is part of a hindlimb stylopod. - TermGenie - 2014-12-02T18:40:47Z - cell - CL:2000076 - hindlimb stylopod vein endothelial cell - - - - Any vein endothelial cell that is part of a hindlimb stylopod. - GOC:TermGenie - @@ -47297,19 +19180,7 @@ plexiform layer using GABA. - Any striated muscle cell that is part of a skeletal muscle tissue of pectoralis major. - TermGenie - 2014-12-02T18:48:17Z - cell - CL:2000077 - skeletal muscle tissue of pectoralis major striated muscle cell - - - - Any striated muscle cell that is part of a skeletal muscle tissue of pectoralis major. - GOC:TermGenie - @@ -47317,19 +19188,7 @@ plexiform layer using GABA. - Any pericyte cell that is part of a placenta. - TermGenie - 2014-12-02T18:51:03Z - cell - CL:2000078 - placental pericyte - - - - Any pericyte cell that is part of a placenta. - GOC:TermGenie - @@ -47337,19 +19196,7 @@ plexiform layer using GABA. - Any mesenchymal stem cell of the bone marrow that is part of a femur. - TermGenie - 2014-12-02T19:07:31Z - cell - CL:2000079 - mesenchymal stem cell of femoral bone marrow - - - - Any mesenchymal stem cell of the bone marrow that is part of a femur. - GOC:TermGenie - @@ -47357,19 +19204,7 @@ plexiform layer using GABA. - Any mesenchymal stem cell of adipose that is part of a abdomen. - TermGenie - 2014-12-02T19:10:34Z - cell - CL:2000080 - mesenchymal stem cell of abdominal adipose - - - - Any mesenchymal stem cell of adipose that is part of a abdomen. - GOC:TermGenie - @@ -47377,19 +19212,7 @@ plexiform layer using GABA. - Any melanocyte of skin that is part of a skin of face. - TermGenie - 2014-12-02T19:10:40Z - cell - CL:2000081 - melanocyte of skin of face - - - - Any melanocyte of skin that is part of a skin of face. - GOC:TermGenie - @@ -47398,19 +19221,7 @@ plexiform layer using GABA. - Any melanocyte of skin that is part of a skin of prepuce of penis. - TermGenie - 2014-12-02T19:10:45Z - cell - CL:2000082 - melanocyte of foreskin - - - - Any melanocyte of skin that is part of a skin of prepuce of penis. - GOC:TermGenie - @@ -47418,19 +19229,7 @@ plexiform layer using GABA. - Any hair follicle dermal papilla cell that is part of a scalp. - TermGenie - 2014-12-02T19:10:50Z - cell - CL:2000083 - hair follicle dermal papilla cell of scalp - - - - Any hair follicle dermal papilla cell that is part of a scalp. - GOC:TermGenie - @@ -47439,19 +19238,7 @@ plexiform layer using GABA. - Any goblet cell that is part of a conjunctiva. - TermGenie - 2014-12-02T19:28:38Z - cell - CL:2000084 - conjunctiva goblet cell - - - - Any goblet cell that is part of a conjunctiva. - GOC:TermGenie - @@ -47460,19 +19247,7 @@ plexiform layer using GABA. - Any mononuclear cell that is part of a umbilical cord. - TermGenie - 2014-12-02T20:14:16Z - cell - CL:2000085 - mononuclear cell of umbilical cord - - - - Any mononuclear cell that is part of a umbilical cord. - GOC:TermGenie - @@ -47481,19 +19256,7 @@ plexiform layer using GABA. - Any basket cell that is part of a neocortex. - TermGenie - 2014-12-24T00:37:19Z - cell - CL:2000086 - neocortex basket cell - - - - Any basket cell that is part of a neocortex. - GOC:TermGenie - @@ -47502,19 +19265,7 @@ plexiform layer using GABA. - Any basket cell that is part of a dentate gyrus of hippocampal formation. - TermGenie - 2014-12-24T00:37:24Z - cell - CL:2000087 - dentate gyrus of hippocampal formation basket cell - - - - Any basket cell that is part of a dentate gyrus of hippocampal formation. - GOC:TermGenie - @@ -47523,19 +19274,7 @@ plexiform layer using GABA. - Any basket cell that is part of a Ammon's horn. - TermGenie - 2014-12-24T00:37:30Z - cell - CL:2000088 - Ammon's horn basket cell - - - - Any basket cell that is part of a Ammon's horn. - GOC:TermGenie - @@ -47543,20 +19282,7 @@ plexiform layer using GABA. - The principal cell type of the dentate gyrus. - TermGenie - 2015-02-23T05:48:23Z - cell - CL:2000089 - The granule cell has a characteristic cone-shaped tree of spiny apical dendrites. - dentate gyrus of hippocampal formation granule cell - - - - The principal cell type of the dentate gyrus. - GOC:TermGenie - @@ -47565,19 +19291,7 @@ plexiform layer using GABA. - Any stellate cell that is part of a dentate gyrus of hippocampal formation. - TermGenie - 2015-02-23T05:48:40Z - cell - CL:2000090 - dentate gyrus of hippocampal formation stellate cell - - - - Any stellate cell that is part of a dentate gyrus of hippocampal formation. - GOC:TermGenie - @@ -47585,19 +19299,7 @@ plexiform layer using GABA. - Any microvascular endothelial cell that is part of a endometrial blood vessel. - TermGenie - 2015-03-31T21:02:36Z - cell - CL:2000091 - endometrial microvascular endothelial cells - - - - Any microvascular endothelial cell that is part of a endometrial blood vessel. - GOC:TermGenie - @@ -47606,19 +19308,7 @@ plexiform layer using GABA. - Any keratinocyte that is part of a hair follicle. - TermGenie - 2015-03-31T21:07:02Z - cell - CL:2000092 - hair follicular keratinocyte - - - - Any keratinocyte that is part of a hair follicle. - GOC:TermGenie - @@ -47626,19 +19316,7 @@ plexiform layer using GABA. - Any fibroblast of lung that is part of a bronchus. - TermGenie - 2015-03-31T21:16:22Z - cell - CL:2000093 - bronchus fibroblast of lung - - - - Any fibroblast of lung that is part of a bronchus. - GOC:TermGenie - @@ -47646,19 +19324,7 @@ plexiform layer using GABA. - Any epithelial cell of viscerocranial mucosa that is part of a nasal cavity respiratory epithelium. - TermGenie - 2015-03-31T22:25:17Z - cell - CL:2000094 - nasal cavity respiratory epithelium epithelial cell of viscerocranial mucosa - - - - Any epithelial cell of viscerocranial mucosa that is part of a nasal cavity respiratory epithelium. - GOC:TermGenie - @@ -47667,19 +19333,7 @@ plexiform layer using GABA. - Any hematopoietic stem cell that is part of a umbilical cord blood. - TermGenie - 2015-05-26T18:58:34Z - cell - CL:2000095 - cord blood hematopoietic stem cell - - - - Any hematopoietic stem cell that is part of a umbilical cord blood. - GOC:TermGenie - @@ -47688,19 +19342,7 @@ plexiform layer using GABA. - Any fibroblast that is part of a reticular layer of dermis. - TermGenie - 2015-08-11T16:28:16Z - cell - CL:2000096 - reticular layer of dermis fibroblast - - - - Any fibroblast that is part of a reticular layer of dermis. - GOC:TermGenie - @@ -47709,22 +19351,10 @@ plexiform layer using GABA. - Any dopaminergic neuron that is part of a midbrain. - TermGenie - 2015-12-03T16:42:40Z - cell - CL:2000097 - midbrain dopaminergic neuron - - - - - Any dopaminergic neuron that is part of a midbrain. - GOC:TermGenie - + - + diff --git a/src/ontology/cl.owl b/src/ontology/cl.owl index 95a05cf4a..1f364b14c 100644 --- a/src/ontology/cl.owl +++ b/src/ontology/cl.owl @@ -28,7 +28,7 @@ xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#" xmlns:ncbitaxon="http://purl.obolibrary.org/obo/ncbitaxon#"> - + Alexander Diehl Ceri van Slyke Chris Mungall @@ -3423,7 +3423,7 @@ boundary_of: http://purl.obolibrary.org/obo/RO_0002000 Process(P2) is directly regulated by process(P1) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2. - GOC:dos + GOC:dos @@ -3442,7 +3442,7 @@ boundary_of: http://purl.obolibrary.org/obo/RO_0002000 Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1. - GOC:dos + GOC:dos @@ -3461,7 +3461,7 @@ boundary_of: http://purl.obolibrary.org/obo/RO_0002000 Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1. - GOC:dos + GOC:dos @@ -3482,7 +3482,7 @@ boundary_of: http://purl.obolibrary.org/obo/RO_0002000 A 'has effector activity' B if A and B are GO molecular functions (GO_0003674), A 'has component activity' B and B is the effector (output function) of B. Each compound function has only one effector activity. - GOC:dos + GOC:dos @@ -5971,7 +5971,7 @@ Each of these 3 primitives can be composed to yield a cross-product of different c executes activity in d if and only if c enables p and p occurs_in d. Assuming no action at a distance by gene products, if a gene product enables (is capable of) a process that occurs in some structure, it must have at least some part in that structure. GOC:cjm - GOC:dos + GOC:dos @@ -23349,9 +23349,13 @@ Covers cells actively being cultured or stored in a quiescent state for future u - + + false + http://purl.obolibrary.org/obo/DDANAT_0000002 cell + Obsoleted becuase this term has an overly general name, no definition, and by it's classification appears to refer to a very specific cell type in dictystelium. If needed, the term should be in DDANAT - probably as a subclass of http://purl.obolibrary.org/obo/DDANAT_0000002 anterior cell + true @@ -56350,7 +56354,7 @@ radial glial cells acting as neural progenitors throughout life. A CD8-positive, alpha beta memory T cell with the phenotype CD45RA-positive, CD45RO-negative, and CCR7-negative. GOC:add - GOC:dos + GOC:dos PMID:15032595 PMID:16237082 @@ -72754,7 +72758,7 @@ radial glial cells acting as neural progenitors throughout life. A transversely striated, synctial muscle cell, formed by the fusion of myoblasts. - GOC:dos + GOC:dos GOC:tfm ISBN:0323052908 PMID:22274696 @@ -86081,7 +86085,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u Any hematopoietic cell that is a precursor of some other hematopoietic cell type. - GOC:dos + GOC:dos @@ -86181,7 +86185,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u A muscle cell that is part of some somatic muscle. - GOC:dos + GOC:dos @@ -86251,7 +86255,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u A muscle cell that is part of some visceral muscle - GOC:dos + GOC:dos @@ -86287,7 +86291,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u A visceral muscle cell that is striated. Examples include the visceral muscle cells of arhtropods. - GOC:dos + GOC:dos @@ -86328,7 +86332,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u A visceral muscle that is transversely striated. Examples include the visceral muscle cells of arthropods. - GOC:dos + GOC:dos @@ -86604,7 +86608,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u A skeletal muscle satellite cell that undergoes symmetric division to produce two adult skeleltal muscle myoblasts. - GOC:dos + GOC:dos PMID:23303905 @@ -86711,7 +86715,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u An endocrine cell that is part of the pancreas. - GOC:dos + GOC:dos @@ -86745,7 +86749,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u A neuron that release noradrenaline (noriphinephrine) as a neurotransmitter. - GOC:dos + GOC:dos @@ -86779,7 +86783,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u An epithelial cell that is part of the epithelium of a tracheal tube in an open tracheal system, such as that found in insects. - GOC:dos + GOC:dos @@ -88432,7 +88436,7 @@ plexiform layer using GABA. A cell that, by division or terminal differentiation, can give rise to other cell types. - GOC:dos + GOC:dos @@ -103123,7 +103127,7 @@ plexiform layer using GABA. A large, granular, liver specific natural killer cell that adheres to the endothelial cells of the hepatic sinusoid. - GOC:dos + GOC:dos PMID:9408963 @@ -104992,14 +104996,6 @@ plexiform layer using GABA. - - - - - - - - @@ -106581,7 +106577,7 @@ plexiform layer using GABA. The vesicular release of dopamine. from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. - GOC:dos + GOC:dos GOC:dph @@ -116871,7 +116867,7 @@ plexiform layer using GABA. The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. - GOC:dos + GOC:dos GOC:go_curators @@ -117526,7 +117522,7 @@ plexiform layer using GABA. The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter, pore or motor protein. - GOC:dos + GOC:dos GOC:dph GOC:jl GOC:mah @@ -118765,7 +118761,7 @@ plexiform layer using GABA. A mitotic cell cycle in which chromosomes are replicated and sister chromatids separate, but spindle formation, nuclear membrane breakdown and nuclear division do not occur, resulting in an increased number of chromosomes in the cell. GOC:curators - GOC:dos + GOC:dos GOC:expert_vm @@ -119249,7 +119245,7 @@ plexiform layer using GABA. Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions. - GOC:dos + GOC:dos GOC:mah @@ -119337,7 +119333,7 @@ plexiform layer using GABA. The vesicular release of acetylcholine from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. - GOC:dos + GOC:dos Wikipedia:Cholinergic @@ -121118,7 +121114,7 @@ plexiform layer using GABA. The series of events in which an ultraviolet radiation (UV light) stimulus is received and converted into a molecular signal. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers. - GOC:dos + GOC:dos GOC:go_curators GOC:hb ISBN:0198506732 @@ -121142,7 +121138,7 @@ plexiform layer using GABA. The series of events in which a gravitational stimulus is received and converted into a molecular signal. - GOC:dos + GOC:dos GOC:hb @@ -125034,7 +125030,7 @@ plexiform layer using GABA. A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. - GOC:dos + GOC:dos GOC:mah ISBN:0815316194 @@ -125058,7 +125054,7 @@ plexiform layer using GABA. The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. - GOC:dos + GOC:dos GOC:go_curators @@ -129915,7 +129911,7 @@ plexiform layer using GABA. A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle. - GOC:dos + GOC:dos GOC:mah @@ -129974,7 +129970,7 @@ plexiform layer using GABA. The component of the plasma membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. - GOC:dos + GOC:dos GOC:mah @@ -130064,7 +130060,7 @@ plexiform layer using GABA. The component of the organelle membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. - GOC:dos + GOC:dos GOC:mah @@ -130096,7 +130092,7 @@ plexiform layer using GABA. The component of the organelle membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. - GOC:dos + GOC:dos GOC:mah @@ -135971,7 +135967,7 @@ plexiform layer using GABA. A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. - GOC:dos + GOC:dos GOC:mah @@ -138226,7 +138222,7 @@ plexiform layer using GABA. The vesicular release of glutamate from a presynapse, across a chemical synapse, the subsequent activation of glutamate receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. - GOC:dos + GOC:dos @@ -139685,7 +139681,7 @@ plexiform layer using GABA. response to chemical stimulus - GOC:dos + GOC:dos @@ -154990,7 +154986,7 @@ plexiform layer using GABA. The series of events involved in sensory perception in which a sensory stimulus is received and converted into a molecular signal. GOC:ai - GOC:dos + GOC:dos GOC:dph @@ -155034,7 +155030,7 @@ plexiform layer using GABA. The series of events in which a chemical stimulus is received and converted into a molecular signal as part of sensory perception. GOC:ai - GOC:dos + GOC:dos @@ -155078,7 +155074,7 @@ plexiform layer using GABA. The series of events involved in visual perception in which a light stimulus is received and converted into a molecular signal. GOC:ai - GOC:dos + GOC:dos @@ -155477,7 +155473,7 @@ plexiform layer using GABA. The series of events in which a temperature stimulus is received and converted into a molecular signal as part of thermoception. GOC:ai - GOC:dos + GOC:dos @@ -155528,7 +155524,7 @@ plexiform layer using GABA. The series of events in which a temperature stimulus is received and converted into a molecular signal as part of sensory perception. GOC:ai - GOC:dos + GOC:dos @@ -155571,7 +155567,7 @@ plexiform layer using GABA. The series of events in which a light stimulus is received by a cell and converted into a molecular signal as part of the sensory perception of light. GOC:ai - GOC:dos + GOC:dos @@ -155614,7 +155610,7 @@ plexiform layer using GABA. The series of events in which a mechanical stimulus is received and converted into a molecular signal as part of sensory perception. GOC:ai - GOC:dos + GOC:dos @@ -155679,7 +155675,7 @@ plexiform layer using GABA. The series of events involved in the perception of touch in which a mechanical stimulus is received and converted into a molecular signal. GOC:ai - GOC:dos + GOC:dos @@ -155700,7 +155696,7 @@ plexiform layer using GABA. The series of events by which a mechanical stimulus is received and converted into a molecular signal. GOC:ai - GOC:dos + GOC:dos @@ -157356,7 +157352,7 @@ plexiform layer using GABA. Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation. GOC:ai - GOC:dos + GOC:dos @@ -157550,7 +157546,7 @@ plexiform layer using GABA. Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation. GOC:ai - GOC:dos + GOC:dos @@ -159239,7 +159235,7 @@ plexiform layer using GABA. Any process, occuring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation. GOC:ai - GOC:dos + GOC:dos GOC:dph GOC:tb @@ -160023,7 +160019,7 @@ plexiform layer using GABA. The vesicular release of gamma-aminobutyric acid (GABA). from a presynapse, across a chemical synapse, the subsequent activation of GABA receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. - GOC:dos + GOC:dos ISBN:0126603030 @@ -160980,7 +160976,7 @@ plexiform layer using GABA. The vesicular release of glycine from a presynapse, across a chemical synapse, the subsequent activation of glycine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. - GOC:dos + GOC:dos @@ -161173,7 +161169,7 @@ plexiform layer using GABA. A compound molecular function in which an effector function is controlled by one or more regulatory components. - GOC:dos + GOC:dos GOC:pdt @@ -165407,7 +165403,7 @@ plexiform layer using GABA. The series of events involved in the perception of gravity in which a sensory mechanical stimulus is received and converted into a molecular signal. - GOC:dos + GOC:dos GOC:mah @@ -167743,7 +167739,7 @@ plexiform layer using GABA. All of the contents of a cilium, excluding the plasma membrane surrounding the cilium. GOC:BHF GOC:cilia - GOC:dos + GOC:dos PMID:17895364 @@ -168151,7 +168147,7 @@ plexiform layer using GABA. Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism. - GOC:dos + GOC:dos @@ -168172,7 +168168,7 @@ plexiform layer using GABA. The lipid bilayer that forms the outer-most layer of an organelle. - GOC:dos + GOC:dos @@ -168213,7 +168209,7 @@ plexiform layer using GABA. A membrane that is a part of a larger membrane. Examples include the apical region of the plasma membrane of an epithelial cell and the various regions of the endoplasmic reticulum membrane. - GOC:dos + GOC:dos @@ -168248,7 +168244,7 @@ plexiform layer using GABA. A membrane that is a (regional) part of the plasma membrane. - GOC:dos + GOC:dos @@ -168281,7 +168277,7 @@ plexiform layer using GABA. The attachment of one cell to another cell via adhesion molecules. - GOC:dos + GOC:dos @@ -168375,7 +168371,7 @@ plexiform layer using GABA. The process in which an anion is transported across a membrane. - GOC:dos + GOC:dos GOC:vw @@ -168395,7 +168391,7 @@ plexiform layer using GABA. The directed movement of some substance from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis. - GOC:dos + GOC:dos @@ -168420,7 +168416,7 @@ plexiform layer using GABA. Any process that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance. - GOC:dos + GOC:dos @@ -168445,7 +168441,7 @@ plexiform layer using GABA. A molecular function that modulates the activity of a gene product or complex. Examples include enzyme regulators and channel regulators. - GOC:dos + GOC:dos GOC:pt @@ -168467,7 +168463,7 @@ plexiform layer using GABA. The part of a synapse that is part of the presynaptic cell. - GOC:dos + GOC:dos @@ -168487,7 +168483,7 @@ plexiform layer using GABA. The part of a synapse that is part of the post-synaptic cell. - GOC:dos + GOC:dos @@ -168518,7 +168514,7 @@ plexiform layer using GABA. Any protein complex that is part of a membrane. - GOC:dos + GOC:dos @@ -168548,7 +168544,7 @@ plexiform layer using GABA. Any protein complex that is part of the plasma membrane. - GOC:dos + GOC:dos @@ -168583,7 +168579,7 @@ plexiform layer using GABA. Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by the renal system. - GOC:dos + GOC:dos @@ -168604,7 +168600,7 @@ plexiform layer using GABA. Any protein complex that is part of the plasma membrane and which functions as a receptor. - GOC:dos + GOC:dos @@ -168624,7 +168620,7 @@ plexiform layer using GABA. Any lipid bilayer that completely encloses some structure, and all the proteins embedded in it or attached to it. Examples include the plasma membrane and most organelle membranes. - GOC:dos + GOC:dos @@ -168643,7 +168639,7 @@ plexiform layer using GABA. The process in which genetic material, in the form of nuclear chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. Nuclear chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles. - GOC:dos + GOC:dos @@ -168681,7 +168677,7 @@ plexiform layer using GABA. Any process that modulates the frequency, rate or extent of excitatory postsynaptic potential (EPSP). EPSP is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential. - GOC:dos + GOC:dos @@ -168720,7 +168716,7 @@ plexiform layer using GABA. Any process that modulates the frequency, rate or extent of inhibitory postsynaptic potential (IPSP). IPSP is a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential. - GOC:dos + GOC:dos @@ -168796,7 +168792,7 @@ plexiform layer using GABA. The actin cytoskeleton that is part of a postsynapse - GOC:dos + GOC:dos @@ -168833,7 +168829,7 @@ plexiform layer using GABA. Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. - GOC:dos + GOC:dos GOC:dph GOC:go_curators GOC:tb @@ -168855,7 +168851,7 @@ plexiform layer using GABA. Cell-cell signaling from pre to post-synapse, across the synaptic cleft - GOC:dos + GOC:dos @@ -168892,7 +168888,7 @@ plexiform layer using GABA. The component of the postsynaptic membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. - GOC:dos + GOC:dos GOC:mah @@ -168928,7 +168924,7 @@ plexiform layer using GABA. Synaptic transmission that results in an excitatory postsynaptic potential. - GOC:dos + GOC:dos @@ -168963,7 +168959,7 @@ plexiform layer using GABA. Synaptic transmission that results in an inhibitory postsynaptic potential. - GOC:dos + GOC:dos @@ -168999,7 +168995,7 @@ plexiform layer using GABA. Any vesicle-mediated transport that occurs in a synapse - GOC:dos + GOC:dos @@ -169030,7 +169026,7 @@ plexiform layer using GABA. The component of the postsynaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. - GOC:dos + GOC:dos @@ -169048,7 +169044,7 @@ plexiform layer using GABA. A cellular component that consists of an indeterminate number of proteins or macromolecular complexes, organized into a regular, higher-order structure such as a polymer, sheet, network or a fiber. - GOC:dos + GOC:dos @@ -169066,7 +169062,7 @@ plexiform layer using GABA. A polymeric supramolecular structure. - GOC:dos + GOC:dos @@ -169190,7 +169186,7 @@ plexiform layer using GABA. The actin cytoskeleton that is part of a presynapse - GOC:dos + GOC:dos @@ -169228,7 +169224,7 @@ plexiform layer using GABA. Any process, acting in the postsynapse that results in modulation of chemical synaptic transmission. - GOC:dos + GOC:dos @@ -169266,7 +169262,7 @@ plexiform layer using GABA. Any process, acting in the presynapse that results in modulation of chemical synaptic transmission. - GOC:dos + GOC:dos @@ -169302,7 +169298,7 @@ plexiform layer using GABA. Any process that modulates the frequency, rate or extent of trans-synaptic signaling. - GOC:dos + GOC:dos @@ -169342,7 +169338,7 @@ plexiform layer using GABA. The component of the synaptic membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. - GOC:dos + GOC:dos GOC:mah @@ -169361,7 +169357,7 @@ plexiform layer using GABA. A cytoplasmic, membrane bound vesicle that is capable of fusing to the plasma membrane to release its contents into the extracellular space. - GOC:dos + GOC:dos @@ -169381,7 +169377,7 @@ plexiform layer using GABA. A polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure. - GOC:dos + GOC:dos @@ -169400,7 +169396,7 @@ plexiform layer using GABA. A component of the cytoskeleton consisting of a homo or heteropolymeric fiber constructed from an indeterminate number of protein subunits. - GOC:dos + GOC:dos @@ -169443,7 +169439,7 @@ plexiform layer using GABA. A G protein-coupled receptor activity occurring in the postsynaptic membrane that is part of a GPCR signaling pathway that positively regulates ion channel activity in the postsynaptic membrane. - GOC:dos + GOC:dos @@ -169490,7 +169486,7 @@ plexiform layer using GABA. The pathway leading to secretion of a neurotransmitter from the presynapse as part of synaptic transmission. - GOC:dos + GOC:dos @@ -169509,7 +169505,7 @@ plexiform layer using GABA. Cell-cell signaling to, from or or within a synapse. - GOC:dos + GOC:dos @@ -169528,7 +169524,7 @@ plexiform layer using GABA. Cell-cell signaling in either direction across the synaptic cleft. - GOC:dos + GOC:dos @@ -169560,7 +169556,7 @@ plexiform layer using GABA. Cell-cell signaling between presynapse and postsynapse, across the synaptic cleft, that modulates the synaptic transmission properties of the synapse. - GOC:dos + GOC:dos @@ -169609,7 +169605,7 @@ plexiform layer using GABA. The part of synaptic transmission occurring in the post-synapse: a signal transduction pathway consisting of neurotransmitter receptor activation and its effects on postsynaptic membrane potential and the ionic composition of the postsynaptic cytosol. - GOC:dos + GOC:dos @@ -169645,7 +169641,7 @@ plexiform layer using GABA. Any (proper) part of the cytoplasm of a single cell of sufficient size to still be considered cytoplasm" - GOC:dos + GOC:dos @@ -169683,7 +169679,7 @@ plexiform layer using GABA. The portion of the cytoskeleton contained within the presynapse. - GOC:dos + GOC:dos @@ -169720,7 +169716,7 @@ plexiform layer using GABA. The portion of the cytoskeleton contained within the postsynapse. - GOC:dos + GOC:dos PMID:19889835 @@ -169757,7 +169753,7 @@ plexiform layer using GABA. Any process that modulates synaptic transmission by regulating a catabolic process occurring at a presynapse. - GOC:dos + GOC:dos @@ -169793,7 +169789,7 @@ plexiform layer using GABA. Any process that modulates synaptic transmission by regulating a catabolic process occurring at a postsynapse. - GOC:dos + GOC:dos @@ -169846,7 +169842,7 @@ plexiform layer using GABA. Any signal release from a synapse. - GOC:dos + GOC:dos @@ -169879,7 +169875,7 @@ plexiform layer using GABA. The component of the synaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. - GOC:dos + GOC:dos @@ -547305,7 +547301,7 @@ plexiform layer using GABA. A muscle organ that consists of skeletal muscle tissue ensheathed in epimysium, that develops from myotome and that is innervated by some somatic motor neuron. Skeletal muscles are typically attached (via a tendon) to a bone but there are exceptions (e.g. intrinsic tongue muscles). - GOC:dos + GOC:dos @@ -557924,7 +557920,7 @@ plexiform layer using GABA. An exocrine gland that is part of a integumental system. - GOC:dos + GOC:dos